SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from supfam.org. Please contact us if you experience any problems.


Tudor domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   SH3-like barrel [ 50036] (21)
Superfamily:   Tudor/PWWP/MBT [ 63748] (4)
Family:   Tudor domain [ 63749] (7)


Family statistics
Genomes (67) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 557 1,333 16
Proteins 443 1,082 11


Enzyme Commission (EC)

(
show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on acid anhydrides0.0000000000002646Least InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides; involved in cellular an0Moderately InformativeDirect
Enzyme Commission (EC)RNA helicase0InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details) Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cellular phenotype0.00808Least InformativeInherited
Mammalian Phenotype (MP)endocrine/exocrine gland phenotype0.008505Least InformativeInherited
Mammalian Phenotype (MP)abnormal cell death0.1192Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal reproductive system physiology0.1648Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal reproductive system morphology0.2119Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal primary sex determination0.00009505InformativeDirect
Mammalian Phenotype (MP)abnormal male reproductive system physiology0.2484InformativeInherited
Mammalian Phenotype (MP)abnormal germ cell morphology0.2871InformativeInherited
Mammalian Phenotype (MP)abnormal spermatogenesis0.2941InformativeInherited
Mammalian Phenotype (MP)abnormal testis morphology0.3121InformativeInherited
Mammalian Phenotype (MP)arrest of spermatogenesis0.0000000484Highly InformativeDirect
Mammalian Phenotype (MP)male infertility0.00001194Highly InformativeDirect
Mammalian Phenotype (MP)small testis0.00004505Highly InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)cell0Least InformativeDirect
Zebrafish Anatomy (ZA)motile cell0.0005292InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)trunk0Least InformativeDirect
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect
Xenopus ANatomical entity (XAN)urogenital system0.1017Least InformativeInherited
Xenopus ANatomical entity (XAN)germ cell0.002308Moderately InformativeInherited

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0.000000004515Least InformativeDirect
Enzyme Commission (EC)Oxidoreductases0.1215Least InformativeInherited
Enzyme Commission (EC)Acting on acid anhydrides0.00000181Moderately InformativeDirect
Enzyme Commission (EC)Acting on ester bonds0.2785Moderately InformativeInherited
Enzyme Commission (EC)Acting on ATP; involved in cellular and subcellular movement7.357e-16InformativeDirect
Enzyme Commission (EC)Acting on the CH-CH group of donors0.0000006461InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0.0000000079Highly InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 46 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Tudor/PWWP/MBT domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]