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Skp1 dimerisation domain-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Skp1 dimerisation domain-like [ 81384]
Superfamily:   Skp1 dimerisation domain-like [ 81382]
Families:   Skp1 dimerisation domain-like [ 81380] (2)

Superfamily statistics
Genomes (487) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 2,339 5,048 5
Proteins 2,284 4,942 5

Functional annotation
General category General
Detailed category Protein interaction

Function annotation of SCOP domain superfamilies

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)larval development variant0Least InformativeDirect
Worm Phenotype (WP)larval growth variant0Least InformativeDirect
Worm Phenotype (WP)cell development variant0.00000000000003349Least InformativeDirect
Worm Phenotype (WP)cell physiology variant0.00000000006739Least InformativeDirect
Worm Phenotype (WP)cell morphology variant0.0000000122Least InformativeDirect
Worm Phenotype (WP)organism environmental stimulus response variant0.000001863Least InformativeDirect
Worm Phenotype (WP)organism metabolism processing variant0.671Least InformativeInherited
Worm Phenotype (WP)germ cell differentiation variant0Moderately InformativeDirect
Worm Phenotype (WP)body region morphology variant0Moderately InformativeDirect
Worm Phenotype (WP)organism segment morphology variant0Moderately InformativeDirect
Worm Phenotype (WP)early embryonic lethal4.49e-16Moderately InformativeDirect
Worm Phenotype (WP)cell organization biogenesis variant8.972e-16Moderately InformativeDirect
Worm Phenotype (WP)apoptosis variant0.0000000000000277Moderately InformativeDirect
Worm Phenotype (WP)germ cell development variant0.0000000000004518Moderately InformativeDirect
Worm Phenotype (WP)cell cycle variant0.0000000678Moderately InformativeDirect
Worm Phenotype (WP)cell division variant0.00001805Moderately InformativeDirect
Worm Phenotype (WP)protein interaction variant0.02721Moderately InformativeInherited
Worm Phenotype (WP)cell homeostasis metabolism variant1Moderately InformativeInherited
Worm Phenotype (WP)early larval arrest0InformativeDirect
Worm Phenotype (WP)neuron migration variant0InformativeDirect
Worm Phenotype (WP)cytoskeleton organization biogenesis variant0InformativeDirect
Worm Phenotype (WP)accumulated germline cell corpses0InformativeDirect
Worm Phenotype (WP)meiotic chromosome organization variant0InformativeDirect
Worm Phenotype (WP)pachytene progression during oogenesis variant0InformativeDirect
Worm Phenotype (WP)embryonic cell organization biogenesis variant0InformativeDirect
Worm Phenotype (WP)chemical hypersensitive0.00000007136InformativeDirect
Worm Phenotype (WP)chromosome segregation variant0.0009272InformativeDirect
Worm Phenotype (WP)mitotic spindle defective early emb0Highly InformativeDirect
Worm Phenotype (WP)L1 larval development variant0Highly InformativeDirect
Worm Phenotype (WP)cytoplasmic appearance defective early emb0Highly InformativeDirect
Worm Phenotype (WP)apoptosis increased0Highly InformativeDirect
Worm Phenotype (WP)cell proliferation increased0Highly InformativeDirect
Worm Phenotype (WP)spindle position variant0Highly InformativeDirect
Worm Phenotype (WP)embryonic arrest0Highly InformativeDirect
Worm Phenotype (WP)cytoplasmic streaming defective0Highly InformativeDirect
Worm Phenotype (WP)body axis morphology variant0Highly InformativeDirect
Worm Phenotype (WP)resistant to protein aggregation induced paralysis0.000000001166Highly InformativeDirect
Worm Phenotype (WP)X chromosome nondisjunction0.00001786Highly InformativeDirect

Document: WP annotation of SCOP domains

Fly Phenotype (FP)

(show details) Document: FP annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)seed1Least InformativeInherited
Plant ANatomical entity (PAN)portion of meristem tissue1Least InformativeInherited
Plant ANatomical entity (PAN)root system1Least InformativeInherited
Plant ANatomical entity (PAN)shoot axis1Least InformativeInherited
Plant ANatomical entity (PAN)cardinal part of multi-tissue plant structure1Least InformativeInherited
Plant ANatomical entity (PAN)fruit0InformativeDirect
Plant ANatomical entity (PAN)portion of ground tissue0.001754InformativeInherited
Plant ANatomical entity (PAN)primary root0.000002058Highly InformativeDirect
Plant ANatomical entity (PAN)lateral root0.00001215Highly InformativeDirect
Plant ANatomical entity (PAN)cortex0.00002659Highly InformativeDirect
Plant ANatomical entity (PAN)shoot apical meristem0.0001984Highly InformativeDirect
Plant structure DEvelopment stage (PDE)seedling development stage0.000001646InformativeDirect

Document: AP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Worm Phenotype (WP) · Fly Phenotype (FP) · Arabidopsis Plant Ontology (AP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Alignments of sequences to 4 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.

Browse and view proteins in genomes which have different domain combinations including a Skp1 dimerisation domain-like domain.

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.

Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 4 hidden Markov models representing the Skp1 dimerisation domain-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.

Jump to [ Top of page · SCOP classification · Functional annotation · Worm Phenotype (WP) · Fly Phenotype (FP) · Arabidopsis Plant Ontology (AP) · Internal database links ]