SUPERFAMILY 1.75 HMM library and genome assignments server

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DEATH effector domain, DED family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   DEATH domain [ 47985]
Superfamily:   DEATH domain [ 47986] (4)
Family:   DEATH effector domain, DED [ 81388] (2)

Family statistics
Genomes (53) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 64 151 3
Proteins 64 151 3

Disease Ontology (DO)

show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)organ system cancer0Least InformativeDirect
Disease Ontology (DO)cell type cancer0Moderately InformativeDirect
Disease Ontology (DO)benign neoplasm0Moderately InformativeDirect
Disease Ontology (DO)lower respiratory tract disease0.0007261Moderately InformativeDirect
Disease Ontology (DO)hematologic cancer0.006024Moderately InformativeInherited
Disease Ontology (DO)cell type benign neoplasm0InformativeDirect
Disease Ontology (DO)myeloid neoplasm0.00009433InformativeDirect
Disease Ontology (DO)lung carcinoma0.0002319InformativeDirect
Disease Ontology (DO)multiple myeloma0.00002075Highly InformativeDirect

Document: DO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0Least InformativeDirect
Enzyme Commission (EC)Acting on peptide bonds (peptidases)0Moderately InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Enzyme Commission (EC) ]

Internal database links

Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Superfamily level     Family level

Alignments of sequences to 24 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.

Superfamily level

Browse and view proteins in genomes which have different domain combinations including a DEATH domain domain.

Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.

Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Enzyme Commission (EC) · Internal database links ]