ISP transmembrane anchor superfamily

SCOP classification

• Root: SCOP hierarchy in SUPERFAMILY [ 0] (11)
• Class: Membrane and cell surface proteins and peptides [ 56835] (58)
• Fold: Single transmembrane helix [ 81407] (38)
• Superfamily: ISP transmembrane anchor [ 81502]
• Families: ISP transmembrane anchor [ 81501] (2)

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Superfamily statistics

	Genomes (450)	Uniprot 2018_03 genome	PDB chains (SCOP 1.75)
Domains	623	1,896	4
Proteins	623	1,892	4

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Functional annotation

• General category: Metabolism
• Detailed category: Energy

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Enzyme Commission (EC)

Highlighted in gray are those with FDR_all>0.001

	EC term	FDR (all)	IC level	SDEO level	Annotation (direct or inherited)
Enzyme Commission (EC)	Acting on diphenols and related substances as dono	0	1.782	--	DIRECT
Enzyme Commission (EC)	Oxidoreductases	0	0.2975	Least Informative	DIRECT
Enzyme Commission (EC)	With a cytochrome as acceptor	0	2.083	Highly Informative	DIRECT

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Enzyme Commission (EC)

Highlighted in gray are those with FDR_all>0.001

	EC term	FDR (all)	IC level	SDEC level	Annotation (direct or inherited)
Enzyme Commission (EC)	Hydron translocation or charge separation linked to oxidoreductase reactions	0	1.651	--	DIRECT
Enzyme Commission (EC)	Translocases	0	1.339	--	DIRECT
Enzyme Commission (EC)	Catalysing the translocation of hydrons	0	1.505	Informative	DIRECT
Enzyme Commission (EC)	Quinol--cytochrome-c reductase	0	2.174	Highly Informative	DIRECT

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InterPro annotation

• Cross references: IPR004192 SSF81502 Protein matches
• Abstract: The ubiquinol cytochrome c reductase (cytochrome bc1) complex is a respiratory chain that generates an elctrochemical potential coupled to ATP synthesis. The bc1 complex contains 11 subunits, 3 respiratory subunits (cytochrome B, cytochrome C1, Rieske protein), 2 core proteins and 6 low-molecular weight proteins. Each subunit of the cytochrome bc1 complex provides a single helix (this family) to make up the transmembrane region of the complex.

InterPro database

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