Trehalose-6-phosphate synthase, OtsA family

SCOP classification

• Root: SCOP hierarchy in SUPERFAMILY [ 0] (11)
• Class: Alpha and beta proteins (a/b) [ 51349] (147)
• Fold: UDP-Glycosyltransferase/glycogen phosphorylase [ 53755]
• Superfamily: UDP-Glycosyltransferase/glycogen phosphorylase [ 53756] (11)
• Family: Trehalose-6-phosphate synthase, OtsA [ 82540]

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Family statistics

	Genomes (1,211)	Uniprot 2018_03 genome	PDB chains (SCOP 1.75)
Domains	2,812	13,578	2
Proteins	2,809	13,561	2

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Enzyme Commission (EC)

Highlighted in gray are those with FDR_all>0.001

	EC term	FDR (all)	IC level	SDEO level	Annotation (direct or inherited)
Enzyme Commission (EC)	Alpha,alpha-trehalose-phosphate synthase (UDP-form	0	2.741	--	DIRECT
Enzyme Commission (EC)	Transferases	0	0	--	DIRECT
Enzyme Commission (EC)	Glycosyltransferases	0	0.993	Moderately Informative	DIRECT
Enzyme Commission (EC)	Hexosyltransferases	0	1.264	Informative	DIRECT

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Yeast Phenotype (YP)

Highlighted in gray are those with FDR_all>0.001

	YP term	FDR (all)	IC level	SDYP level	Annotation (direct or inherited)
Yeast Phenotype (YP)	cellular processes	0	0.09186	--	DIRECT
Yeast Phenotype (YP)	stress resistance	0	0.1452	--	DIRECT
Yeast Phenotype (YP)	competitive fitness	0	0.1116	--	DIRECT
Yeast Phenotype (YP)	fitness	0	0.1096	--	DIRECT
Yeast Phenotype (YP)	chronological lifespan	0	1.666	--	DIRECT
Yeast Phenotype (YP)	development	0	1.143	Moderately Informative	DIRECT
Yeast Phenotype (YP)	lifespan	0	1.403	Informative	DIRECT

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Arabidopsis Plant Ontology (AP)

Highlighted in gray are those with FDR_all>0.001

	AP term	FDR (all)	IC level	SDAP level	Annotation (direct or inherited)
Plant ANatomical entity (PAN)	plant cell	0	0.1228	--	DIRECT
Plant ANatomical entity (PAN)	collective plant structure	0	0.01555	--	DIRECT
Plant ANatomical entity (PAN)	plant organ	0	0.2391	--	DIRECT
Plant ANatomical entity (PAN)	multi-tissue plant structure	0	0.2335	--	DIRECT
Plant ANatomical entity (PAN)	plant axis	0	0.3257	--	DIRECT
Plant ANatomical entity (PAN)	vascular leaf primordium	0	2.299	--	DIRECT
Plant ANatomical entity (PAN)	whole plant	0	0.3507	--	DIRECT
Plant ANatomical entity (PAN)	shoot axis	0	0.3985	--	DIRECT
Plant ANatomical entity (PAN)	shoot system	0	0.05272	--	DIRECT
Plant ANatomical entity (PAN)	primordium	0.00000000000001148	1.822	--	DIRECT
Plant ANatomical entity (PAN)	cardinal part of multi-tissue plant structure	0.1156	0.437	--	INHERITED FROM: root tip
Plant ANatomical entity (PAN)	leaf	0.1165	0.4282	--	INHERITED FROM: rosette leaf
Plant ANatomical entity (PAN)	root system	0.1369	0.4584	--	INHERITED FROM: root tip
Plant ANatomical entity (PAN)	cardinal organ part	0.3179	0.4385	--	INHERITED FROM: root tip
Plant ANatomical entity (PAN)	phyllome	0.351	0.3234	--	INHERITED FROM: rosette leaf
Plant ANatomical entity (PAN)	portion of plant tissue	0.5108	0.1621	--	INHERITED FROM: phyllome primordium || primordium || vascular leaf primordium
Plant ANatomical entity (PAN)	collective plant organ structure	1	0.03998	--	INHERITED FROM: phyllome primordium || rosette leaf || vegetative shoot apex || shoot apex || root tip || vascular leaf primordium || shoot axis || shoot system
Plant ANatomical entity (PAN)	plant structure	1	0	--	INHERITED FROM: rosette leaf || primordium || collective plant structure || multi-tissue plant structure || shoot apex || shoot system || plant organ || whole plant || phyllome primordium || plant ovule || vegetative shoot apex || vascular leaf primordium || root tip || plant axis || plant cell || shoot axis
Plant ANatomical entity (PAN)	shoot apex	0	0.481	Least Informative	DIRECT
Plant ANatomical entity (PAN)	vascular leaf	0.1088	0.437	Least Informative	INHERITED FROM: rosette leaf
Plant ANatomical entity (PAN)	portion of meristem tissue	0.1971	0.5892	Least Informative	INHERITED FROM: primordium || phyllome primordium || vascular leaf primordium
Plant ANatomical entity (PAN)	root	0.4973	0.4679	Least Informative	INHERITED FROM: root tip
Plant ANatomical entity (PAN)	root tip	0.000000000000651	1.725	Informative	DIRECT
Plant ANatomical entity (PAN)	rosette leaf	0.000003901	1.725	Informative	DIRECT
Plant ANatomical entity (PAN)	vegetative shoot apex	0.000000000000001862	2.123	Highly Informative	DIRECT
Plant ANatomical entity (PAN)	phyllome primordium	0.000000000000002793	2.123	Highly Informative	DIRECT
Plant ANatomical entity (PAN)	plant ovule	0.0000245	1.901	Highly Informative	DIRECT
Plant structure DEvelopment stage (PDE)	floral organ differentiation stage	0	0.07163	--	DIRECT
Plant structure DEvelopment stage (PDE)	floral organ formation stage	0	0.07163	--	DIRECT
Plant structure DEvelopment stage (PDE)	collective plant organ structure development stage	0	0.0282	--	DIRECT
Plant structure DEvelopment stage (PDE)	corolla development stage	0	0.1484	--	DIRECT
Plant structure DEvelopment stage (PDE)	flowering stage	0	0.1648	--	DIRECT
Plant structure DEvelopment stage (PDE)	sporophyte vegetative stage	0	0.1593	--	DIRECT
Plant structure DEvelopment stage (PDE)	phyllome development stage	0	0.3879	--	DIRECT
Plant structure DEvelopment stage (PDE)	collective phyllome structure development stage	0	0.07163	--	DIRECT
Plant structure DEvelopment stage (PDE)	reproductive shoot system development stage	0	0.0371	--	DIRECT
Plant structure DEvelopment stage (PDE)	1 main shoot growth stage	0	0.3245	--	DIRECT
Plant structure DEvelopment stage (PDE)	whole plant development stage	0	0.1547	--	DIRECT
Plant structure DEvelopment stage (PDE)	plant organ development stage	0	0.06127	--	DIRECT
Plant structure DEvelopment stage (PDE)	plant embryo stage	0	0.2319	--	DIRECT
Plant structure DEvelopment stage (PDE)	leaf development stage	1	0.3879	--	INHERITED FROM: 4 leaf senescence stage
Plant structure DEvelopment stage (PDE)	shoot system development stage	1	0.02956	--	INHERITED FROM: phyllome development stage || reproductive shoot system development stage || floral organ formation stage || floral organ differentiation stage || flowering stage || corolla development stage || plant organ development stage || 4 leaf senescence stage
Plant structure DEvelopment stage (PDE)	sporophyte development stage	1	0.1584	--	INHERITED FROM: LP.08 eight leaves visible stage || LP.12 twelve leaves visible stage || E expanded cotyledon stage || LP.10 ten leaves visible stage || LP.06 six leaves visible stage || sporophyte vegetative stage || C globular stage || 1 main shoot growth stage || D bilateral stage || F mature embryo stage || LP.04 four leaves visible stage || plant embryo stage || LP.02 two leaves visible stage
Plant structure DEvelopment stage (PDE)	leaf production stage	1	0.3272	--	INHERITED FROM: LP.02 two leaves visible stage || LP.10 ten leaves visible stage || LP.04 four leaves visible stage || LP.08 eight leaves visible stage || LP.12 twelve leaves visible stage || LP.06 six leaves visible stage
Plant structure DEvelopment stage (PDE)	life of whole plant stage	1	0.1584	--	INHERITED FROM: sporophyte vegetative stage || C globular stage || LP.10 ten leaves visible stage || E expanded cotyledon stage || LP.12 twelve leaves visible stage || F mature embryo stage || LP.04 four leaves visible stage || D bilateral stage || LP.06 six leaves visible stage || LP.08 eight leaves visible stage || LP.02 two leaves visible stage || plant embryo stage || 1 main shoot growth stage
Plant structure DEvelopment stage (PDE)	flower development stage	1	0.05402	--	INHERITED FROM: corolla development stage || flowering stage || floral organ differentiation stage || floral organ formation stage
Plant structure DEvelopment stage (PDE)	LP.10 ten leaves visible stage	0	0.4234	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	E expanded cotyledon stage	0	0.2861	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	LP.12 twelve leaves visible stage	0	0.479	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	LP.08 eight leaves visible stage	0	0.4752	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	C globular stage	0	0.3087	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	LP.06 six leaves visible stage	0	0.4268	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	D bilateral stage	0	0.301	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	4 leaf senescence stage	0	0.3895	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	LP.02 two leaves visible stage	0	0.4603	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	F mature embryo stage	0	0.3205	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	LP.04 four leaves visible stage	0	0.3479	Least Informative	DIRECT

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Enzyme Commission (EC)

Highlighted in gray are those with FDR_all>0.001

	EC term	FDR (all)	IC level	SDEC level	Annotation (direct or inherited)
Enzyme Commission (EC)	Hexosyltransferases	0	1.65	--	DIRECT
Enzyme Commission (EC)	Alpha,alpha-trehalose-phosphate synthase (UDP-forming)	0	2.929	--	DIRECT
Enzyme Commission (EC)	Alpha,alpha-trehalose-phosphate synthase (ADP-forming)	0	3.23	--	DIRECT
Enzyme Commission (EC)	Trehalose-phosphatase	0.000000000006261	2.929	--	DIRECT
Enzyme Commission (EC)	Glucosylglycerol-phosphate synthase	0.000001981	3.23	--	DIRECT
Enzyme Commission (EC)	Transferases	0	0.3972	Least Informative	DIRECT
Enzyme Commission (EC)	Hydrolases	1	0.4043	Least Informative	INHERITED FROM: Trehalose-phosphatase
Enzyme Commission (EC)	Acting on ester bonds	0.3595	0.8756	Moderately Informative	INHERITED FROM: Trehalose-phosphatase
Enzyme Commission (EC)	Glycosyltransferases	0	1.378	Informative	DIRECT
Enzyme Commission (EC)	Phosphoric monoester hydrolases	0.005568	1.338	Informative	INHERITED FROM: Trehalose-phosphatase

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