Noggin family

SCOP classification

• Root: SCOP hierarchy in SUPERFAMILY [ 0] (11)
• Class: Small proteins [ 56992] (90)
• Fold: Cystine-knot cytokines [ 57500]
• Superfamily: Cystine-knot cytokines [ 57501] (7)
• Family: Noggin [ 82904]

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Family statistics

	Genomes (62)	Uniprot 2018_03 genome	PDB chains (SCOP 1.75)
Domains	101	275	1
Proteins	101	275	1

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Xenopus Anatomy (XA)

Highlighted in gray are those with FDR_all>0.001

	XA term	FDR (all)	IC level	SDXA level	Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)	compound organ	0	0.2177	--	DIRECT
Xenopus ANatomical entity (XAN)	neural fold	0	1.824	--	DIRECT
Xenopus ANatomical entity (XAN)	primary germ layer	0	0.6748	--	DIRECT
Xenopus ANatomical entity (XAN)	pre-chordal neural plate	0	1.824	--	DIRECT
Xenopus ANatomical entity (XAN)	anatomical group	0	0.1408	--	DIRECT
Xenopus ANatomical entity (XAN)	head region	0	0.4759	--	DIRECT
Xenopus ANatomical entity (XAN)	organism subdivision	0	0.1679	--	DIRECT
Xenopus ANatomical entity (XAN)	visual system	0	1.321	--	DIRECT
Xenopus ANatomical entity (XAN)	anatomical structure	0	0	--	DIRECT
Xenopus ANatomical entity (XAN)	multicellular anatomical structure	0	0.1131	--	DIRECT
Xenopus ANatomical entity (XAN)	anatomical region	0	0.1803	--	DIRECT
Xenopus ANatomical entity (XAN)	neural plate	0	1.635	--	DIRECT
Xenopus ANatomical entity (XAN)	central nervous system	0	0.5841	--	DIRECT
Xenopus ANatomical entity (XAN)	anatomical system	1	0.283	--	INHERITED FROM: neural tube || nervous system || forebrain || brain || optic vesicle || musculoskeletal system || sensory system || central nervous system || visual system
Xenopus ANatomical entity (XAN)	whole organism	1	0.0884	--	INHERITED FROM: neural plate || head region || brain || forebrain || nervous system || anterior neural fold || neural tube || anatomical group || cavitated compound organ || multicellular anatomical structure || mesoderm || ectoderm || compound organ || tissue || anatomical region || central nervous system || pre-chordal neural plate || visual system || neural fold || sensory system || multi-tissue structure || neuroectoderm || primordium || musculoskeletal system || organism subdivision || embryonic structure || optic vesicle || head || primary germ layer
Xenopus ANatomical entity (XAN)	embryo	0	0.5979	Least Informative	DIRECT
Xenopus ANatomical entity (XAN)	cavitated compound organ	0	0.2685	Least Informative	DIRECT
Xenopus ANatomical entity (XAN)	nervous system	0	0.5619	Least Informative	DIRECT
Xenopus ANatomical entity (XAN)	head	0	0.4777	Least Informative	DIRECT
Xenopus ANatomical entity (XAN)	tissue	0	0.4672	Least Informative	DIRECT
Xenopus ANatomical entity (XAN)	multi-tissue structure	0	1.066	Moderately Informative	DIRECT
Xenopus ANatomical entity (XAN)	sensory system	0	1.158	Moderately Informative	DIRECT
Xenopus ANatomical entity (XAN)	embryonic structure	0	1.149	Moderately Informative	DIRECT
Xenopus ANatomical entity (XAN)	brain	0	0.7859	Moderately Informative	DIRECT
Xenopus ANatomical entity (XAN)	musculoskeletal system	0	1.087	Moderately Informative	DIRECT
Xenopus ANatomical entity (XAN)	ectoderm	0	0.9357	Moderately Informative	DIRECT
Xenopus ANatomical entity (XAN)	neuroectoderm	0	1.374	Informative	DIRECT
Xenopus ANatomical entity (XAN)	mesoderm	0	1.285	Informative	DIRECT
Xenopus ANatomical entity (XAN)	forebrain	0	1.786	Highly Informative	DIRECT
Xenopus ANatomical entity (XAN)	primordium	0	1.751	Highly Informative	DIRECT
Xenopus ANatomical entity (XAN)	neural tube	0	1.824	Highly Informative	DIRECT
Xenopus ANatomical entity (XAN)	anterior neural fold	0	1.911	Highly Informative	DIRECT
Xenopus ANatomical entity (XAN)	optic vesicle	0	1.911	Highly Informative	DIRECT
Xenopus DEvelopment stage (XDE)	NF stage	0	0.01895	--	DIRECT
Xenopus DEvelopment stage (XDE)	embryonic stage	0	1.006	Moderately Informative	DIRECT

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