DNA replication initiator (cdc21/cdc54) N-terminal domain family

SCOP classification

• Root: SCOP hierarchy in SUPERFAMILY [ 0] (11)
• Class: All beta proteins [ 48724] (174)
• Fold: OB-fold [ 50198] (16)
• Superfamily: Nucleic acid-binding proteins [ 50249] (16)
• Family: DNA replication initiator (cdc21/cdc54) N-terminal domain [ 89332]

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Family statistics

	Genomes (128)	Uniprot 2018_03 genome	PDB chains (SCOP 1.75)
Domains	134	873	1
Proteins	134	873	1

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Enzyme Commission (EC)

Highlighted in gray are those with FDR_all>0.001

	EC term	FDR (all)	IC level	SDEO level	Annotation (direct or inherited)
Enzyme Commission (EC)	DNA helicase	0	1.223	--	DIRECT
Enzyme Commission (EC)	Hydrolases	0	0.01852	--	DIRECT
Enzyme Commission (EC)	Acting on acid anhydrides	0	0.7283	Least Informative	DIRECT
Enzyme Commission (EC)	Acting on acid anhydrides; involved in cellular an	0	1.001	Moderately Informative	DIRECT

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Disease Ontology (DO)

Highlighted in gray are those with FDR_all>0.001

	DO term	FDR (all)	IC level	SDDO level	Annotation (direct or inherited)
Disease Ontology (DO)	disease of cellular proliferation	0	0.2322	--	DIRECT
Disease Ontology (DO)	cancer	0	0.2555	--	DIRECT

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Mouse Phenotype (MP)

Highlighted in gray are those with FDR_all>0.001

	MP term	FDR (all)	IC level	SDMP level	Annotation (direct or inherited)
Mammalian Phenotype (MP)	abnormal chromosome stability	0.00000000000002751	1.825	--	DIRECT
Mammalian Phenotype (MP)	decreased fibroblast proliferation	0.000000009476	2.603	--	DIRECT
Mammalian Phenotype (MP)	abnormal pluripotent precursor cell morphology	0.00000002416	2.603	--	DIRECT
Mammalian Phenotype (MP)	abnormal fibroblast proliferation	0.00000004883	2.603	--	DIRECT
Mammalian Phenotype (MP)	spontaneous chromosome breakage	0.0000002446	2.603	--	DIRECT
Mammalian Phenotype (MP)	increased classified tumor incidence	0.000001657	1.324	--	DIRECT
Mammalian Phenotype (MP)	abnormal classified tumor incidence	0.000001771	1.324	--	DIRECT
Mammalian Phenotype (MP)	increased organ/body region tumor incidence	0.000002484	1.223	--	DIRECT
Mammalian Phenotype (MP)	abnormal organ/body region tumor incidence	0.000002892	1.223	--	DIRECT
Mammalian Phenotype (MP)	increased tumor incidence	0.000006669	1.172	--	DIRECT
Mammalian Phenotype (MP)	abnormal tumor incidence	0.00001481	1.141	--	DIRECT
Mammalian Phenotype (MP)	altered tumor susceptibility	0.00001641	1.141	--	DIRECT
Mammalian Phenotype (MP)	reticulocytosis	0.00002293	2.302	--	DIRECT
Mammalian Phenotype (MP)	abnormal reticulocyte cell number	0.00003243	2.302	--	DIRECT
Mammalian Phenotype (MP)	abnormal erythroid lineage cell morphology	0.000299	1.457	--	DIRECT
Mammalian Phenotype (MP)	increased myeloid cell number	0.0008106	2.302	--	DIRECT
Mammalian Phenotype (MP)	abnormal cell physiology	0.002172	0.6209	--	INHERITED FROM: decreased cell proliferation || abnormal chromosome stability || decreased fibroblast proliferation || chromosomal instability || spontaneous chromosome breakage || abnormal fibroblast proliferation
Mammalian Phenotype (MP)	abnormal hematopoietic cell morphology	0.006358	0.7167	--	INHERITED FROM: abnormal reticulocyte cell number || increased myeloid cell number || abnormal erythroid lineage cell morphology || reticulocytosis
Mammalian Phenotype (MP)	preweaning lethality	0.008342	0.7055	--	INHERITED FROM: postnatal lethality, incomplete penetrance || prenatal lethality
Mammalian Phenotype (MP)	abnormal reticulocyte morphology	0.008967	2.302	--	INHERITED FROM: abnormal reticulocyte cell number || reticulocytosis
Mammalian Phenotype (MP)	abnormal hematopoietic system morphology/development	0.0112	0.6686	--	INHERITED FROM: reticulocytosis || increased myeloid cell number || abnormal erythroid lineage cell morphology || abnormal reticulocyte cell number
Mammalian Phenotype (MP)	abnormal gland morphology	0.0152	0.7519	--	INHERITED FROM: increased gland tumor incidence
Mammalian Phenotype (MP)	abnormal survival	0.01847	0.6441	--	INHERITED FROM: prenatal lethality || postnatal lethality, incomplete penetrance
Mammalian Phenotype (MP)	abnormal cell proliferation	0.02571	1.324	--	INHERITED FROM: decreased cell proliferation || decreased fibroblast proliferation || abnormal fibroblast proliferation
Mammalian Phenotype (MP)	embryo phenotype	0.03614	0.8708	--	INHERITED FROM: abnormal pluripotent precursor cell morphology
Mammalian Phenotype (MP)	abnormal myeloid cell number	0.04301	1.758	--	INHERITED FROM: reticulocytosis || abnormal reticulocyte cell number || increased myeloid cell number
Mammalian Phenotype (MP)	abnormal cell morphology	0.08146	1.324	--	INHERITED FROM: abnormal cell nucleus morphology
Mammalian Phenotype (MP)	abnormal embryonic tissue morphology	0.4355	1.281	--	INHERITED FROM: abnormal pluripotent precursor cell morphology
Mammalian Phenotype (MP)	chromosome breakage	0.7988	2.302	--	INHERITED FROM: spontaneous chromosome breakage
Mammalian Phenotype (MP)	abnormal hematopoietic cell number	0.9293	0.8473	--	INHERITED FROM: abnormal reticulocyte cell number || increased myeloid cell number || reticulocytosis
Mammalian Phenotype (MP)	cellular phenotype	0.004735	0.5387	Least Informative	INHERITED FROM: chromosomal instability || decreased fibroblast proliferation || abnormal chromosome stability || abnormal cell nucleus morphology || abnormal fibroblast proliferation || spontaneous chromosome breakage || decreased cell proliferation
Mammalian Phenotype (MP)	endocrine/exocrine gland phenotype	0.02092	0.6947	Least Informative	INHERITED FROM: increased gland tumor incidence
Mammalian Phenotype (MP)	hematopoietic system phenotype	0.02155	0.5945	Least Informative	INHERITED FROM: reticulocytosis || increased myeloid cell number || abnormal erythroid lineage cell morphology || abnormal reticulocyte cell number
Mammalian Phenotype (MP)	mortality/aging	0.02731	0.5424	Least Informative	INHERITED FROM: postnatal lethality, incomplete penetrance || prenatal lethality
Mammalian Phenotype (MP)	neoplasm	0.00002984	1.035	Moderately Informative	DIRECT
Mammalian Phenotype (MP)	prenatal lethality	0.0002667	0.9129	Moderately Informative	DIRECT
Mammalian Phenotype (MP)	abnormal embryo morphology	0.01606	1.112	Moderately Informative	INHERITED FROM: abnormal pluripotent precursor cell morphology
Mammalian Phenotype (MP)	increased hematopoietic cell number	0.06167	1.188	Moderately Informative	INHERITED FROM: reticulocytosis || increased myeloid cell number
Mammalian Phenotype (MP)	abnormal myeloid cell morphology	0.1858	0.9904	Moderately Informative	INHERITED FROM: reticulocytosis || abnormal reticulocyte cell number || abnormal erythroid lineage cell morphology || increased myeloid cell number
Mammalian Phenotype (MP)	lethality during fetal growth through weaning	0.3016	1.035	Moderately Informative	INHERITED FROM: postnatal lethality, incomplete penetrance
Mammalian Phenotype (MP)	decreased cell proliferation	0.00002657	1.603	Informative	DIRECT
Mammalian Phenotype (MP)	increased gland tumor incidence	0.0001124	1.649	Informative	DIRECT
Mammalian Phenotype (MP)	postnatal lethality	0.02549	1.524	Informative	INHERITED FROM: postnatal lethality, incomplete penetrance
Mammalian Phenotype (MP)	chromosomal instability	0.0000000000000236	1.825	Highly Informative	DIRECT
Mammalian Phenotype (MP)	abnormal cell nucleus morphology	0.000002389	1.825	Highly Informative	DIRECT
Mammalian Phenotype (MP)	postnatal lethality, incomplete penetrance	0.0002448	1.825	Highly Informative	DIRECT

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Worm Phenotype (WP)

Highlighted in gray are those with FDR_all>0.001

	WP term	FDR (all)	IC level	SDWP level	Annotation (direct or inherited)
Worm Phenotype (WP)	embryonic lethal	0	0.046	--	DIRECT
Worm Phenotype (WP)	lethal	0	0.00521	--	DIRECT
Worm Phenotype (WP)	fertility variant	0	0.05937	--	DIRECT
Worm Phenotype (WP)	development variant	0	0.001482	--	DIRECT
Worm Phenotype (WP)	morphology variant	0	0.046	--	DIRECT
Worm Phenotype (WP)	organism development variant	0	0.00297	--	DIRECT
Worm Phenotype (WP)	organ system morphology variant	0	0.7516	--	DIRECT
Worm Phenotype (WP)	organ system physiology variant	0	0.04518	--	DIRECT
Worm Phenotype (WP)	organism physiology variant	0	0.1342	--	DIRECT
Worm Phenotype (WP)	organism homeostasis metabolism variant	0	0.1444	--	DIRECT
Worm Phenotype (WP)	reproductive system physiology variant	0	0.05515	--	DIRECT
Worm Phenotype (WP)	embryonic development variant	0	0.04518	--	DIRECT
Worm Phenotype (WP)	fertility reduced	0	0.06449	--	DIRECT
Worm Phenotype (WP)	sister chromatid segregation defective early emb	0.000000000003108	2.468	--	DIRECT
Worm Phenotype (WP)	hydroxyurea hypersensitive	0.000000000004784	2.769	--	DIRECT
Worm Phenotype (WP)	exaggerated asynchrony early emb	0.000000000008632	2.769	--	DIRECT
Worm Phenotype (WP)	nuclear appearance number defective early emb	0.00000000002961	2.292	--	DIRECT
Worm Phenotype (WP)	hydroxyurea response variant	0.0000000001215	2.769	--	DIRECT
Worm Phenotype (WP)	relative cell cycle timing defective early emb	0.0000000001403	2.468	--	DIRECT
Worm Phenotype (WP)	cytokinesis defective early emb	0.0000000007719	1.866	--	DIRECT
Worm Phenotype (WP)	nucleus reforms cell division remnant early emb	0.0000000009276	2.468	--	DIRECT
Worm Phenotype (WP)	cell cycle timing defective early emb	0.000000001777	2.468	--	DIRECT
Worm Phenotype (WP)	cytokinesis variant	0.000000002215	1.689	--	DIRECT
Worm Phenotype (WP)	chromosome segregation variant	0.000000005163	1.814	--	DIRECT
Worm Phenotype (WP)	multiple cytoplasmic cavities early emb	0.000000006006	2.292	--	DIRECT
Worm Phenotype (WP)	male gonad development variant	0.00000004515	1.924	--	DIRECT
Worm Phenotype (WP)	nuclear number variant	0.00000007249	1.866	--	DIRECT
Worm Phenotype (WP)	somatic gonad morphology variant	0.0000001033	1.866	--	DIRECT
Worm Phenotype (WP)	cytoplasmic morphology defective early emb	0.0000002114	2.167	--	DIRECT
Worm Phenotype (WP)	no differentiated gametes	0.000000436	1.814	--	DIRECT
Worm Phenotype (WP)	no germ line	0.000000446	1.814	--	DIRECT
Worm Phenotype (WP)	somatic gonad development variant	0.000001443	1.655	--	DIRECT
Worm Phenotype (WP)	embryonic cell physiology variant	0.00001005	1.538	--	DIRECT
Worm Phenotype (WP)	multiple nuclei early emb	0.00001308	2.292	--	DIRECT
Worm Phenotype (WP)	cell cycle defective early emb	0.00001343	2.468	--	DIRECT
Worm Phenotype (WP)	nuclear division variant	0.00002858	1.866	--	DIRECT
Worm Phenotype (WP)	protruding vulva	0.00004357	1.623	--	DIRECT
Worm Phenotype (WP)	reproductive system development variant	0.00007454	1.156	--	DIRECT
Worm Phenotype (WP)	cell component morphology variant	0.0001119	0.8392	--	DIRECT
Worm Phenotype (WP)	nuclear position defective early emb	0.0002225	2.468	--	DIRECT
Worm Phenotype (WP)	cell morphology variant	0.0003856	0.7558	--	DIRECT
Worm Phenotype (WP)	nuclear envelope organization variant	0.0006596	2.769	--	DIRECT
Worm Phenotype (WP)	cytoplasmic appearance variant	0.006574	1.99	--	INHERITED FROM: multiple cytoplasmic cavities early emb || cytoplasmic morphology defective early emb
Worm Phenotype (WP)	gametogenesis variant	0.05552	1.013	--	INHERITED FROM: germ cell differentiation variant || no germ line || no differentiated gametes || germ cell development variant || no oocytes
Worm Phenotype (WP)	nuclear number defective early emb	0.06501	2.292	--	INHERITED FROM: multiple nuclei early emb
Worm Phenotype (WP)	drug response variant	0.1946	1.135	--	INHERITED FROM: drug hypersensitive || hydroxyurea hypersensitive || hydroxyurea response variant
Worm Phenotype (WP)	gonad morphology variant	0.2051	1.306	--	INHERITED FROM: gonad arm morphology variant || somatic gonad morphology variant
Worm Phenotype (WP)	hermaphrodite reproductive system morphology variant	0.439	1.426	--	INHERITED FROM: protruding vulva || vulva morphology variant
Worm Phenotype (WP)	organelle organization biogenesis variant	0.7113	1.306	--	INHERITED FROM: nuclear position defective early emb || nucleus reforms cell division remnant early emb
Worm Phenotype (WP)	physiology variant	1	0	--	INHERITED FROM: multiple nuclei || nuclear division variant || hydroxyurea response variant || relative cell cycle timing defective early emb || somatic gonad development variant || reproductive system physiology variant || early embryonic lethal || no oocytes || embryonic cell organization biogenesis variant || drug hypersensitive || organism homeostasis metabolism variant || hydroxyurea hypersensitive || nuclear appearance number defective early emb || no differentiated gametes || lethal || cell cycle timing defective early emb || organism physiology variant || cytokinesis defective early emb || cytokinesis variant emb || sister chromatid segregation defective early emb || germ cell development variant || germ cell differentiation variant || embryonic cell physiology variant || male gonad development variant || no germ line || multiple cytoplasmic cavities early emb || development variant || chromosome segregation variant || male somatic gonad development variant || reproductive system development variant || cell physiology variant || embryonic development variant || embryonic lethal || multiple nuclei early emb || fertility variant || nuclear position defective early emb || cytoplasmic morphology defective early emb || nucleus defective early emb || cell cycle defective early emb || nucleus reforms cell division remnant early emb || exaggerated asynchrony early emb || gonad development variant || organ system physiology variant || nuclear number variant || organism development variant || cytokinesis variant || fertility reduced || cell development variant
Worm Phenotype (WP)	cell physiology variant	0	0.5955	Least Informative	DIRECT
Worm Phenotype (WP)	cell development variant	0.0004937	0.6752	Least Informative	DIRECT
Worm Phenotype (WP)	organism environmental stimulus response variant	0.02739	0.6614	Least Informative	INHERITED FROM: hydroxyurea response variant || drug hypersensitive || hydroxyurea hypersensitive
Worm Phenotype (WP)	reproductive system morphology variant	0	1.078	Moderately Informative	DIRECT
Worm Phenotype (WP)	early embryonic lethal	0.000001153	1.178	Moderately Informative	DIRECT
Worm Phenotype (WP)	cell organization biogenesis variant	0.000001355	1.135	Moderately Informative	DIRECT
Worm Phenotype (WP)	germ cell differentiation variant	0.00004171	1.167	Moderately Informative	DIRECT
Worm Phenotype (WP)	cell type morphology variant	0.00007101	0.8878	Moderately Informative	DIRECT
Worm Phenotype (WP)	germ cell development variant	0.0003248	1.013	Moderately Informative	DIRECT
Worm Phenotype (WP)	organ system development variant	0.001104	0.9113	Moderately Informative	INHERITED FROM: somatic gonad development variant || gonad development variant || reproductive system development variant || male somatic gonad development variant || male gonad development variant
Worm Phenotype (WP)	chemical response variant	0.001271	0.9053	Moderately Informative	INHERITED FROM: hydroxyurea response variant || hydroxyurea hypersensitive || drug hypersensitive
Worm Phenotype (WP)	cell division variant	0.006541	1.036	Moderately Informative	INHERITED FROM: sister chromatid segregation defective early emb || multiple nuclei early emb || cytokinesis defective early emb || cytokinesis variant || cytokinesis variant emb
Worm Phenotype (WP)	cell cycle variant	0.0125	1.225	Moderately Informative	INHERITED FROM: cell cycle defective early emb || exaggerated asynchrony early emb || relative cell cycle timing defective early emb || cell cycle timing defective early emb
Worm Phenotype (WP)	cell homeostasis metabolism variant	0.01718	1.036	Moderately Informative	INHERITED FROM: chromosome segregation variant || sister chromatid segregation defective early emb
Worm Phenotype (WP)	cytokinesis variant emb	0.000000001891	1.689	Informative	DIRECT
Worm Phenotype (WP)	embryonic cell organization biogenesis variant	0.000000008509	1.538	Informative	DIRECT
Worm Phenotype (WP)	gonad development variant	0.000003596	1.538	Informative	DIRECT
Worm Phenotype (WP)	drug hypersensitive	0.00002789	1.689	Informative	DIRECT
Worm Phenotype (WP)	vulva morphology variant	0.00007808	1.426	Informative	DIRECT
Worm Phenotype (WP)	nuclear positioning variant	0.002903	1.623	Informative	INHERITED FROM: nucleus reforms cell division remnant early emb || nuclear position defective early emb
Worm Phenotype (WP)	chemical hypersensitive	0.02115	1.388	Informative	INHERITED FROM: hydroxyurea hypersensitive
Worm Phenotype (WP)	embryonic cell morphology variant	0.00000000004169	2.167	Highly Informative	DIRECT
Worm Phenotype (WP)	nucleus defective early emb	0.00000000006071	2.167	Highly Informative	DIRECT
Worm Phenotype (WP)	multiple nuclei	0.00000002174	1.924	Highly Informative	DIRECT
Worm Phenotype (WP)	male somatic gonad development variant	0.00000002679	2.07	Highly Informative	DIRECT
Worm Phenotype (WP)	gonad arm morphology variant	0.00000005705	1.866	Highly Informative	DIRECT
Worm Phenotype (WP)	no oocytes	0.0000003445	1.814	Highly Informative	DIRECT
Worm Phenotype (WP)	nuclear appearance variant	0.0009797	1.814	Highly Informative	DIRECT
Worm Phenotype (WP)	cytoplasmic appearance defective early emb	0.007422	1.99	Highly Informative	INHERITED FROM: multiple cytoplasmic cavities early emb || cytoplasmic morphology defective early emb

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Fly Anatomy (FA)

Highlighted in gray are those with FDR_all>0.001

	FA term	FDR (all)	IC level	SDFA level	Annotation (direct or inherited)
Fly Anatomy (FA)	organism	0	0.06695	--	DIRECT
Fly Anatomy (FA)	larval imaginal tissue	0	1.435	--	DIRECT
Fly Anatomy (FA)	imaginal tissue	0	1.435	--	DIRECT
Fly Anatomy (FA)	multicellular structure	0	0.008955	--	DIRECT
Fly Anatomy (FA)	anatomical structure	1	0	--	INHERITED FROM: organism || larva || multi-tissue structure || imaginal disc || larval imaginal tissue || multicellular structure
Fly Anatomy (FA)	material anatomical entity	1	0	--	INHERITED FROM: multicellular structure || developing material anatomical entity || larval imaginal tissue || imaginal disc || multi-tissue structure || imaginal tissue || larva || organism
Fly Anatomy (FA)	larva	0	0.3763	Least Informative	DIRECT
Fly Anatomy (FA)	multi-tissue structure	0	0.6038	Least Informative	DIRECT
Fly Anatomy (FA)	developing material anatomical entity	0	0.8329	Moderately Informative	DIRECT
Fly Anatomy (FA)	imaginal disc	0	1.435	Informative	DIRECT

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Xenopus Anatomy (XA)

Highlighted in gray are those with FDR_all>0.001

	XA term	FDR (all)	IC level	SDXA level	Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)	genital system	0	0.5751	--	DIRECT
Xenopus ANatomical entity (XAN)	anatomical structure	0	0	--	DIRECT
Xenopus ANatomical entity (XAN)	anatomical group	0	0.1408	--	DIRECT
Xenopus ANatomical entity (XAN)	organism subdivision	0	0.1679	--	DIRECT
Xenopus ANatomical entity (XAN)	compound organ	0	0.2177	--	DIRECT
Xenopus ANatomical entity (XAN)	anatomical region	0	0.1803	--	DIRECT
Xenopus ANatomical entity (XAN)	multicellular anatomical structure	0	0.1131	--	DIRECT
Xenopus ANatomical entity (XAN)	anatomical system	1	0.283	--	INHERITED FROM: urogenital system || genital system
Xenopus ANatomical entity (XAN)	whole organism	1	0.0884	--	INHERITED FROM: urogenital system || genital system || anatomical group || cavitated compound organ || multicellular anatomical structure || compound organ || anatomical region || organism subdivision
Xenopus ANatomical entity (XAN)	urogenital system	0	0.4777	Least Informative	DIRECT
Xenopus ANatomical entity (XAN)	cavitated compound organ	0	0.2685	Least Informative	DIRECT
Xenopus DEvelopment stage (XDE)	NF stage	0	0.01895	--	DIRECT

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Arabidopsis Plant Ontology (AP)

Highlighted in gray are those with FDR_all>0.001

	AP term	FDR (all)	IC level	SDAP level	Annotation (direct or inherited)
Plant ANatomical entity (PAN)	guard cell	0	0.2279	--	DIRECT
Plant ANatomical entity (PAN)	stomatal complex	0	0.2279	--	DIRECT
Plant ANatomical entity (PAN)	epidermal cell	0	0.2152	--	DIRECT
Plant ANatomical entity (PAN)	epidermis	0	0.2046	--	DIRECT
Plant ANatomical entity (PAN)	shoot epidermis	0	0.2224	--	DIRECT
Plant ANatomical entity (PAN)	plant cell	0	0.1228	--	DIRECT
Plant ANatomical entity (PAN)	shoot system	0	0.05272	--	DIRECT
Plant ANatomical entity (PAN)	portion of plant tissue	0	0.1621	--	DIRECT
Plant ANatomical entity (PAN)	plant organ	0	0.2391	--	DIRECT
Plant ANatomical entity (PAN)	shoot epidermal cell	0	0.227	--	DIRECT
Plant ANatomical entity (PAN)	multi-tissue plant structure	0	0.2335	--	DIRECT
Plant ANatomical entity (PAN)	collective plant structure	0	0.01555	--	DIRECT
Plant ANatomical entity (PAN)	plant structure	1	0	--	INHERITED FROM: collective plant structure || multi-tissue plant structure || guard cell || shoot system || portion of plant tissue || stomatal complex || plant organ || epidermis || epidermal cell || shoot epidermal cell || plant cell || shoot epidermis
Plant ANatomical entity (PAN)	collective plant organ structure	1	0.03998	--	INHERITED FROM: guard cell || shoot epidermal cell || stomatal complex || shoot system || shoot epidermis
Plant structure DEvelopment stage (PDE)	whole plant inflorescence detectable stage	0	2.835	--	DIRECT
Plant structure DEvelopment stage (PDE)	sporophyte reproductive stage	0	2.835	--	DIRECT
Plant structure DEvelopment stage (PDE)	whole plant development stage	0.7427	0.1547	--	INHERITED FROM: sporophyte reproductive stage || whole plant inflorescence detectable stage
Plant structure DEvelopment stage (PDE)	life of whole plant stage	1	0.1584	--	INHERITED FROM: whole plant inflorescence detectable stage || sporophyte reproductive stage
Plant structure DEvelopment stage (PDE)	sporophyte development stage	1	0.1584	--	INHERITED FROM: sporophyte reproductive stage || whole plant inflorescence detectable stage

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Enzyme Commission (EC)

Highlighted in gray are those with FDR_all>0.001

	EC term	FDR (all)	IC level	SDEC level	Annotation (direct or inherited)
Enzyme Commission (EC)	DNA helicase	0	1.639	--	DIRECT
Enzyme Commission (EC)	Hydrolases	0	0.4043	Least Informative	DIRECT
Enzyme Commission (EC)	Acting on acid anhydrides	0	1.133	Moderately Informative	DIRECT
Enzyme Commission (EC)	Acting on ATP; involved in cellular and subcellular movement	0	1.385	Informative	DIRECT

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