SPOC domain-like superfamily

DO

Disease Ontology (DO)

	DO term	FDR (all)	SDDO (four levels)	Annotation (direct or inherited)
Disease Ontology (DO)	disease of cellular proliferation	0	--	Direct
Disease Ontology (DO)	cancer	0	--	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

MP

Mouse Phenotype (MP)

	MP term	FDR (all)	SDMP (four levels)	Annotation (direct or inherited)
Mammalian Phenotype (MP)	abnormal leukocyte cell number	0	--	Direct
Mammalian Phenotype (MP)	decreased leukocyte cell number	0	--	Direct
Mammalian Phenotype (MP)	abnormal immune system morphology	0	--	Direct
Mammalian Phenotype (MP)	abnormal immune system cell morphology	0	--	Direct
Mammalian Phenotype (MP)	abnormal lymphocyte cell number	0	--	Direct
Mammalian Phenotype (MP)	abnormal definitive hematopoiesis	0	--	Direct
Mammalian Phenotype (MP)	abnormal hematopoietic system morphology/development	0	--	Direct
Mammalian Phenotype (MP)	abnormal lymphopoiesis	0	--	Direct
Mammalian Phenotype (MP)	abnormal lymphocyte morphology	0	--	Direct
Mammalian Phenotype (MP)	abnormal B cell morphology	0	--	Direct
Mammalian Phenotype (MP)	decreased lymphocyte cell number	0	--	Direct
Mammalian Phenotype (MP)	abnormal leukopoiesis	0	--	Direct
Mammalian Phenotype (MP)	abnormal leukocyte morphology	0	--	Direct
Mammalian Phenotype (MP)	increased hematopoietic cell number	0	--	Direct
Mammalian Phenotype (MP)	decreased hematopoietic cell number	0	--	Direct
Mammalian Phenotype (MP)	abnormal hematopoietic cell morphology	0	--	Direct
Mammalian Phenotype (MP)	abnormal hemopoiesis	0	--	Direct
Mammalian Phenotype (MP)	increased classified tumor incidence	0.0004648	--	Direct
Mammalian Phenotype (MP)	abnormal classified tumor incidence	0.0004835	--	Direct
Mammalian Phenotype (MP)	increased organ/body region tumor incidence	0.0005744	--	Direct
Mammalian Phenotype (MP)	abnormal organ/body region tumor incidence	0.0006211	--	Direct
Mammalian Phenotype (MP)	increased tumor incidence	0.0009392	--	Direct
Mammalian Phenotype (MP)	abnormal tumor incidence	0.0014	--	Inherited
Mammalian Phenotype (MP)	altered tumor susceptibility	0.001477	--	Inherited
Mammalian Phenotype (MP)	immune system phenotype	0	Least Informative	Direct
Mammalian Phenotype (MP)	hematopoietic system phenotype	0	Least Informative	Direct
Mammalian Phenotype (MP)	abnormal blood cell morphology/development	0	Moderately Informative	Direct
Mammalian Phenotype (MP)	abnormal immune system organ morphology	0	Moderately Informative	Direct
Mammalian Phenotype (MP)	abnormal mononuclear cell morphology	0	Moderately Informative	Direct
Mammalian Phenotype (MP)	abnormal hematopoietic cell number	0	Moderately Informative	Direct
Mammalian Phenotype (MP)	abnormal blood cell morphology	0	Moderately Informative	Direct
Mammalian Phenotype (MP)	neoplasm	0.002	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal spleen morphology	0	Informative	Direct
Mammalian Phenotype (MP)	abnormal B cell differentiation	0	Informative	Direct
Mammalian Phenotype (MP)	increased hemolymphoid system tumor incidence	0.00004743	Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

WP

Worm Phenotype (WP)

	WP term	FDR (all)	SDWP (four levels)	Annotation (direct or inherited)
Worm Phenotype (WP)	growth variant	0	--	Direct
Worm Phenotype (WP)	slow growth	0	--	Direct
Worm Phenotype (WP)	developmental timing variant	0	--	Direct
Worm Phenotype (WP)	postembryonic development variant	0	--	Direct
Worm Phenotype (WP)	embryonic lethal	0	--	Direct
Worm Phenotype (WP)	larval arrest	0	--	Direct
Worm Phenotype (WP)	lethal	0	--	Direct
Worm Phenotype (WP)	progeny variant	0	--	Direct
Worm Phenotype (WP)	fertility variant	0	--	Direct
Worm Phenotype (WP)	development variant	0	--	Direct
Worm Phenotype (WP)	morphology variant	0	--	Direct
Worm Phenotype (WP)	organism development variant	0	--	Direct
Worm Phenotype (WP)	organism morphology variant	0	--	Direct
Worm Phenotype (WP)	organ system physiology variant	0	--	Direct
Worm Phenotype (WP)	organism physiology variant	0	--	Direct
Worm Phenotype (WP)	organism homeostasis metabolism variant	0	--	Direct
Worm Phenotype (WP)	reproductive system physiology variant	0	--	Direct
Worm Phenotype (WP)	maternal sterile	0	--	Direct
Worm Phenotype (WP)	hermaphrodite sterile	0	--	Direct
Worm Phenotype (WP)	embryonic development variant	0	--	Direct
Worm Phenotype (WP)	hermaphrodite fertility variant	0	--	Direct
Worm Phenotype (WP)	developmental growth variant	0	--	Direct
Worm Phenotype (WP)	hermaphrodite fertility reduced	0	--	Direct
Worm Phenotype (WP)	fertility reduced	0	--	Direct
Worm Phenotype (WP)	physiology variant	1	--	Inherited
Worm Phenotype (WP)	sterile	1	--	Inherited
Worm Phenotype (WP)	general pace of development variant	0	Least Informative	Direct
Worm Phenotype (WP)	larval lethal	0	Least Informative	Direct
Worm Phenotype (WP)	retarded heterochronic variations	0	Least Informative	Direct
Worm Phenotype (WP)	larval development variant	0	Least Informative	Direct
Worm Phenotype (WP)	larval growth variant	0	Least Informative	Direct
Worm Phenotype (WP)	sterile progeny	0	Moderately Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

FP

Fly Phenotype (FP)

	FP term	FDR (all)	SDFP (four levels)	Annotation (direct or inherited)
Fly Phenotype (FP)	phenotype	0	--	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

FA

Fly Anatomy (FA)

	FA term	FDR (all)	SDFA (four levels)	Annotation (direct or inherited)
Fly Anatomy (FA)	organism	0	--	Direct
Fly Anatomy (FA)	tagma	0	--	Direct
Fly Anatomy (FA)	adult thorax	0	--	Direct
Fly Anatomy (FA)	adult sense organ	0	--	Direct
Fly Anatomy (FA)	sense organ	0	--	Direct
Fly Anatomy (FA)	external sensory organ	0	--	Direct
Fly Anatomy (FA)	anatomical group	0	--	Direct
Fly Anatomy (FA)	non-connected functional system	0	--	Direct
Fly Anatomy (FA)	multicellular structure	0	--	Direct
Fly Anatomy (FA)	anatomical structure	1	--	Inherited
Fly Anatomy (FA)	material anatomical entity	1	--	Inherited
Fly Anatomy (FA)	anterior-posterior subdivision of organism	1	--	Inherited
Fly Anatomy (FA)	adult	0	Least Informative	Direct
Fly Anatomy (FA)	organism subdivision	0	Least Informative	Direct
Fly Anatomy (FA)	thorax	0	Moderately Informative	Direct
Fly Anatomy (FA)	adult tagma	0	Moderately Informative	Direct
Fly Anatomy (FA)	sensory system	0	Moderately Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

XA

Xenopus Anatomy (XA)

	XA term	FDR (all)	SDXA (four levels)	Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)	trunk region	0	--	Direct
Xenopus ANatomical entity (XAN)	genital system	0	--	Direct
Xenopus ANatomical entity (XAN)	male genitalia	0	--	Direct
Xenopus ANatomical entity (XAN)	central nervous system	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical structure	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical group	0	--	Direct
Xenopus ANatomical entity (XAN)	male organism	0	--	Direct
Xenopus ANatomical entity (XAN)	primary germ layer	0	--	Direct
Xenopus ANatomical entity (XAN)	cell	0	--	Direct
Xenopus ANatomical entity (XAN)	organism subdivision	0	--	Direct
Xenopus ANatomical entity (XAN)	compound organ	0	--	Direct
Xenopus ANatomical entity (XAN)	gonad	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical region	0	--	Direct
Xenopus ANatomical entity (XAN)	multicellular anatomical structure	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical system	1	--	Inherited
Xenopus ANatomical entity (XAN)	whole organism	1	--	Inherited
Xenopus ANatomical entity (XAN)	embryo	0	Least Informative	Direct
Xenopus ANatomical entity (XAN)	urogenital system	0	Least Informative	Direct
Xenopus ANatomical entity (XAN)	nervous system	0	Least Informative	Direct
Xenopus ANatomical entity (XAN)	trunk	0	Least Informative	Direct
Xenopus ANatomical entity (XAN)	tissue	0	Least Informative	Direct
Xenopus ANatomical entity (XAN)	cavitated compound organ	0	Least Informative	Direct
Xenopus ANatomical entity (XAN)	ectoderm	0	Moderately Informative	Direct
Xenopus ANatomical entity (XAN)	germ cell	0	Moderately Informative	Direct
Xenopus ANatomical entity (XAN)	testis	0	Moderately Informative	Direct
Xenopus ANatomical entity (XAN)	anatomical entity in vitro	0	Informative	Direct

	XA term	FDR (all)	SDXA (four levels)	Annotation (direct or inherited)
Xenopus DEvelopment stage (XDE)	tadpole stage	0	--	Direct
Xenopus DEvelopment stage (XDE)	metamorphosing tadpole stage	0	--	Direct
Xenopus DEvelopment stage (XDE)	NF stage	0	--	Direct
Xenopus DEvelopment stage (XDE)	post-embryonic stage	0	Least Informative	Direct
Xenopus DEvelopment stage (XDE)	climax stage	0	Moderately Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

EC

Enzyme Commission (EC)

	EC term	FDR (all)	SDEC (four levels)	Annotation (direct or inherited)
Enzyme Commission (EC)	Acting on ATP; involved in cellular and subcellular movement	0	--	Direct
Enzyme Commission (EC)	Hydrolases	0	Least Informative	Direct
Enzyme Commission (EC)	Acting on acid anhydrides	0	Moderately Informative	Direct
Enzyme Commission (EC)	DNA helicase	0	Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

CD

CTD Diseases (CD)

	CD term	FDR (all)	SDCD (four levels)	Annotation (direct or inherited)
CTD Diseases (CD)	Neoplasms by Site	0	--	Direct
CTD Diseases (CD)	Neoplasms	0	Least Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

CC

CTD Chemicals (CC)

	CC term	FDR (all)	SDCC (four levels)	Annotation (direct or inherited)
CTD Chemicals (CC)	Heterocyclic Compounds, Fused-Ring	0	--	Direct
CTD Chemicals (CC)	Carboxylic Acids	0	--	Direct
CTD Chemicals (CC)	Glycosides	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds, 1-Ring	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds, 2-Ring	0	--	Direct
CTD Chemicals (CC)	Hydrocarbons	0	--	Direct
CTD Chemicals (CC)	Inorganic Chemicals	0	--	Direct
CTD Chemicals (CC)	Lipids	0	--	Direct
CTD Chemicals (CC)	Nucleic Acids, Nucleotides, and Nucleosides	0	--	Direct
CTD Chemicals (CC)	Organic Chemicals	0	--	Direct
CTD Chemicals (CC)	Polycyclic Compounds	0	--	Direct
CTD Chemicals (CC)	Pyrans	0	--	Direct
CTD Chemicals (CC)	Enzyme Inhibitors	0.0001658	--	Direct
CTD Chemicals (CC)	Ethanol	0.0007879	--	Direct
CTD Chemicals (CC)	Pharmacologic Actions	0.1684	--	Inherited
CTD Chemicals (CC)	Acids, Noncarboxylic	1	--	Inherited
CTD Chemicals (CC)	Acids	0	Least Informative	Direct
CTD Chemicals (CC)	Benzopyrans	0	Least Informative	Direct
CTD Chemicals (CC)	Carbohydrates	0	Least Informative	Direct
CTD Chemicals (CC)	Electrolytes	0	Least Informative	Direct
CTD Chemicals (CC)	Elements	0	Least Informative	Direct
CTD Chemicals (CC)	Pyrimidines	0	Least Informative	Direct
CTD Chemicals (CC)	Sulfur Compounds	0	Least Informative	Direct
CTD Chemicals (CC)	Chemical Actions and Uses	0.1997	Least Informative	Inherited
CTD Chemicals (CC)	Nucleosides	0	Moderately Informative	Direct
CTD Chemicals (CC)	Sulfur Acids	0	Moderately Informative	Direct
CTD Chemicals (CC)	Nitrogen Compounds	0	Moderately Informative	Direct
CTD Chemicals (CC)	Molecular Mechanisms of Pharmacological Action	0.0001885	Moderately Informative	Direct
CTD Chemicals (CC)	Alcohols	0.005813	Moderately Informative	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

Distribution on sTOL

Plot distribution on species Tree Of Life (sTOL) for this domain, i.e., present or absent across genomes/tips

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SPOC domain-like superfamily