SCOP hierarchy

A

Superfamily	Description [Sunid] (#Children)
Prefixed with A	alpha/beta-Hydrolases [ 53474] (41)
	ARM repeat [ 48371] (23)
	ACT-like [ 55021] (14)
	Actin-like ATPase domain [ 53067] (14)
	Acyl-CoA N-acyltransferases (Nat) [ 55729] (10)
	Aldolase [ 51569] (8)
	Antimicrobial beta-hairpin [ 58252] (8)
	alpha/beta knot [ 75217] (8)
	ADP-ribosylation [ 56399] (7)
	Adenine nucleotide alpha hydrolases-like [ 52402] (6)
	Alkaline phosphatase-like [ 53649] (5)
	Alpha-L RNA-binding motif [ 55174] (5)
	Aminoacid dehydrogenase-like, N-terminal domain [ 53223] (5)
	Antimicrobial helix [ 58269] (5)
	Arabinanase/levansucrase/invertase [ 75005] (5)
	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [ 55874] (4)
	AhpD-like [ 69118] (4)
	all-alpha NTP pyrophosphatases [ 101386] (4)
	A virus capsid protein alpha-helical domain [ 48345] (3)
	ACP-like [ 47336] (3)
	ADC-like [ 50692] (3)
	AF0104/ALDC/Ptd012-like [ 117856] (3)
	AbrB/MazE/MraZ-like [ 89447] (3)
	Acid phosphatase/Vanadium-dependent haloperoxidase [ 48317] (3)
	Acid proteases [ 50630] (3)
	AF2212/PG0164-like [ 141694] (2)
	ALDH-like [ 53720] (2)
	Actin depolymerizing proteins [ 55753] (2)
	Actin-crosslinking proteins [ 50405] (2)
	Activating enzymes of the ubiquitin-like proteins [ 69572] (2)
	Acyl-CoA dehydrogenase C-terminal domain-like [ 47203] (2)
	Acyl-CoA dehydrogenase NM domain-like [ 56645] (2)
	Acylphosphatase/BLUF domain-like [ 54975] (2)
	Aerolisin/ETX pore-forming domain [ 56973] (2)
	Alanine racemase C-terminal domain-like [ 50621] (2)
	AlbA-like [ 82704] (2)
	An anticodon-binding domain of class I aminoacyl-tRNA synthetases [ 48163] (2)
	ApbE-like [ 143631] (2)
	AraD/HMP-PK domain-like [ 53639] (2)
	ArfGap/RecO-like zinc finger [ 57863] (2)
	Arginase/deacetylase [ 52768] (2)
	alpha-catenin/vinculin-like [ 47220] (2)
	alpha-helical ferredoxin [ 46548] (2)
	A DNA-binding domain in eukaryotic transcription factors [ 47454] (1)
	A heparin-binding domain [ 56491] (1)
	A middle domain of Talin 1 [ 109880] (1)
	ABC transporter involved in vitamin B12 uptake, BtuC [ 81345] (1)
	ABC transporter transmembrane region [ 90123] (1)
	ADC synthase [ 56322] (1)
	ADP-ribosylglycohydrolase [ 101478] (1)
	AF0625-like [ 142535] (1)
	AF0941-like [ 140726] (1)
	AF1104-like [ 111321] (1)
	AF1531-like [ 160975] (1)
	AF1782-like [ 158372] (1)
	AF1862-like [ 158568] (1)
	AF2331-like [ 143995] (1)
	AFP III-like domain [ 51269] (1)
	AGR C 984p-like [ 158837] (1)
	AMMECR1-like [ 143447] (1)
	AMPKBI-like [ 160219] (1)
	AN1-like Zinc finger [ 118310] (1)
	ARID-like [ 46774] (1)
	ASF1-like [ 101546] (1)
	ATP synthase [ 58141] (1)
	ATP synthase (F1-ATPase), gamma subunit [ 52943] (1)
	ATP synthase B chain-like [ 161060] (1)
	ATP synthase D chain-like [ 161065] (1)
	ATP synthase beta chain, mitochondrial prepeptide [ 103737] (1)
	ATP-dependent DNA ligase DNA-binding domain [ 117018] (1)
	ATP12-like [ 160909] (1)
	AXH domain [ 102031] (1)
	AbfB domain [ 110221] (1)
	Accessory protein X4 (ORF8, ORF7a) [ 117066] (1)
	Acetamidase/Formamidase-like [ 141130] (1)
	Acetoacetate decarboxylase-like [ 160104] (1)
	Acetyl-CoA synthetase-like [ 56801] (1)
	Acetylcholine receptor fragment (residues alpha 67-76) [ 58615] (1)
	Aconitase B, N-terminal domain [ 74778] (1)
	Aconitase iron-sulfur domain [ 53732] (1)
	Actin-binding peptides [ 70018] (1)
	Actinoxanthin-like [ 49319] (1)
	Activator of Hsp90 ATPase, Aha1 [ 103111] (1)
	Acyl-CoA binding protein [ 47027] (1)
	Ada DNA repair protein, N-terminal domain (N-Ada 10) [ 57884] (1)
	Adenylylcyclase toxin (the edema factor) [ 81298] (1)
	Adhesin YadA, collagen-binding domain [ 101967] (1)
	Adsorption protein p2 [ 89428] (1)
	Agglutinin [ 50382] (1)
	Agglutinin HPA-like [ 141086] (1)
	Agouti-related protein [ 57055] (1)
	Aldehyde ferredoxin oxidoreductase, C-terminal domains [ 48310] (1)
	Aldehyde ferredoxin oxidoreductase, N-terminal domain [ 56228] (1)
	Allene oxide cyclase-like [ 141493] (1)
	Allophycocyanin linker chain (domain) [ 54580] (1)
	Alpha subunit of glutamate synthase, C-terminal domain [ 69336] (1)
	Alpha-2,3/8-sialyltransferase CstII [ 102414] (1)
	Alpha-hemoglobin stabilizing protein AHSP [ 109751] (1)
	Alpha-lytic protease prodomain [ 54806] (1)
	Alpha-macroglobulin receptor domain [ 49410] (1)
	Amb V allergen [ 57296] (1)
	Amidase signature (AS) enzymes [ 75304] (1)
	Amine oxidase N-terminal region [ 54416] (1)
	Amine oxidase catalytic domain [ 49998] (1)
	Aminomethyltransferase beta-barrel domain [ 101790] (1)
	Aminopeptidase/glucanase lid domain [ 101821] (1)
	Ammonium transporter [ 111352] (1)
	Amphiphilic (amphipathic) alpha helix [ 58799] (1)
	Amyloid beta a4 protein copper binding domain (domain 2) [ 89811] (1)
	Amyloid peptides [ 58605] (1)
	An insect antifreeze protein [ 51177] (1)
	Anaphylotoxins (complement system) [ 47686] (1)
	Angiotensin [ 90270] (1)
	Ankyrin repeat [ 48403] (1)
	Annexin [ 47874] (1)
	Antennapedia homeodomain fragments [ 70048] (1)
	Anthrax protective antigen [ 56988] (1)
	Anti-lipopolysaccharide factor [ 54757] (1)
	Anti-sigma factor AsiA [ 69070] (1)
	Anti-sigma factor FlgM [ 101498] (1)
	Antibiotic binding domain of TipA-like multidrug resistance regulators [ 89082] (1)
	Anticancer peptides [ 118391] (1)
	Anticodon-binding domain of PheRS [ 54991] (1)
	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases [ 47323] (1)
	Antifreeze polypeptide HPLC-6 [ 58410] (1)
	Antifungal protein (AGAFP) [ 57598] (1)
	Antigen MPT63/MPB63 (immunoprotective extracellular protein) [ 81982] (1)
	Antimicrobial peptide HP(2-20) [ 90276] (1)
	Antivirulence factor [ 103383] (1)
	ApaG-like [ 110069] (1)
	Api92-like [ 160940] (1)
	Apical membrane antigen 1 [ 82910] (1)
	Apolipophorin-III [ 47857] (1)
	Apolipoprotein [ 47162] (1)
	Apolipoprotein A-I [ 58113] (1)
	Apolipoprotein A-II [ 82936] (1)
	Apyrase [ 101887] (1)
	Aquaporin-like [ 81338] (1)
	Archaeal IMP cyclohydrolase PurO [ 75569] (1)
	Argininosuccinate synthetase, C-terminal domain [ 69864] (1)
	Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain [ 55190] (1)
	Aromatic aminoacid monoxygenases, catalytic and oligomerization domains [ 56534] (1)
	Aromatic compound dioxygenase [ 49482] (1)
	Arp2/3 complex 16 kDa subunit ARPC5 [ 69103] (1)
	Arp2/3 complex 21 kDa subunit ARPC3 [ 69060] (1)
	Arp2/3 complex subunits [ 69645] (1)
	Artificial ankyrin repeat proteins [ 83018] (1)
	Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain [ 57825] (1)
	Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain [ 54893] (1)
	Aspartate receptor, ligand-binding domain [ 47170] (1)
	Aspartate/glutamate racemase [ 53681] (1)
	Aspartate/ornithine carbamoyltransferase [ 53671] (1)
	Assembly domain of cartilage oligomeric matrix protein [ 58006] (1)
	At5g01610-like [ 141562] (1)
	AtpF-like [ 159468] (1)
	Atrial natriuretic peptide [ 58433] (1)
	AttH-like [ 159245] (1)
	Atu1913-like [ 141099] (1)
	Autotransporter [ 103515] (1)
	Ava3019-like [ 160532] (1)
	Avidin/streptavidin [ 50876] (1)
	Avirulence protein AvrPto [ 116854] (1)
	a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) [ 81648] (1)
	alpha-2a adrenergic receptor pepride t3-i2 [ 75757] (1)
	alpha-Amylase inhibitor tendamistat [ 49498] (1)
	alpha-D-mannose-specific plant lectins [ 51110] (1)
	alpha-helical hairpin of p8mtcp1 [ 58784] (1)
	alpha-ketoacid dehydrogenase kinase, N-terminal domain [ 69012] (1)
	alpha-lactalbumin peptide model [ 58683] (1)
	alpha2d [ 58883] (1)
	anthrax toxin protective antigen-receptor complex [ 111490] (1)

B

Superfamily	Description [Sunid] (#Children)
Prefixed with B	Bet v1-like [ 55961] (10)
	beta-beta-alpha zinc fingers [ 57667] (7)
	Bacterial adhesins [ 49401] (6)
	BRCT domain [ 52113] (5)
	BAR/IMD domain-like [ 103657] (4)
	Bacterial luciferase-like [ 51679] (4)
	Barwin-like endoglucanases [ 50685] (4)
	BPTI-like [ 57362] (3)
	Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin [ 47699] (3)
	beta-N-acetylhexosaminidase-like domain [ 55545] (3)
	beta-lactamase/transpeptidase-like [ 56601] (3)
	B12-dependent dehydatase associated subunit [ 52968] (2)
	Bacterial enterotoxins [ 50203] (2)
	Bacterial hemolysins [ 58100] (2)
	Bacterial immunoglobulin/albumin-binding domains [ 46997] (2)
	Bacteriocin immunity protein-like [ 109797] (2)
	Bacteriophage trimeric proteins domain [ 141658] (2)
	beta and beta-prime subunits of DNA dependent RNA-polymerase [ 64484] (2)
	beta-Barrel protease inhibitors [ 50882] (2)
	2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain [ 64158] (1)
	B-box zinc-binding domain [ 57845] (1)
	B-form DNA mimic Ocr [ 101059] (1)
	BAG domain [ 63491] (1)
	BAH domain [ 82061] (1)
	BAS1536-like [ 140500] (1)
	BB1717-like [ 143081] (1)
	BB2672-like [ 160519] (1)
	BC4932-like [ 159121] (1)
	BEACH domain [ 81837] (1)
	BH2638-like [ 158504] (1)
	BH3618-like [ 141457] (1)
	BH3703-like [ 160424] (1)
	BH3980-like [ 158560] (1)
	BLRF2-like [ 160459] (1)
	BRCA2 BRC4 repeat [ 82986] (1)
	BRCA2 helical domain [ 81872] (1)
	BRCA2 tower domain [ 81878] (1)
	BRK domain-like [ 160481] (1)
	BSD domain-like [ 140383] (1)
	BT0923-like [ 160574] (1)
	BTG domain-like [ 160696] (1)
	BTV NS2-like ssRNA-binding domain [ 110132] (1)
	Bacillus cereus metalloprotein-like [ 158430] (1)
	Bacillus phage protein [ 111074] (1)
	Bacterial GAP domain [ 47233] (1)
	Bacterial aa3 type cytochrome c oxidase subunit IV [ 81469] (1)
	Bacterial ba3 type cytochrome c oxidase subunit IIa [ 81473] (1)
	Bacterial exopeptidase dimerisation domain [ 55031] (1)
	Bacterial fluorinating enzyme, C-terminal domain [ 101852] (1)
	Bacterial fluorinating enzyme, N-terminal domain [ 102522] (1)
	Bacterial muramidases [ 48435] (1)
	Bacterial photosystem II reaction centre, L and M subunits [ 81483] (1)
	Bacterial polysaccharide co-polymerase-like [ 160355] (1)
	Bactericidal permeability-increasing protein, BPI [ 55394] (1)
	Bacteriochlorophyll A protein [ 51081] (1)
	Bacteriocin AS-48 [ 47869] (1)
	Bacteriophage HK97 procapsid (prohead II) [ 64612] (1)
	Bacteriophage T4 3D cryo-EM reconstruction [ 103675] (1)
	Baculovirus p35 protein [ 49894] (1)
	Band 7/SPFH domain [ 117892] (1)
	Barrier-to-autointegration factor, BAF [ 47798] (1)
	Barstar fragment [ 83003] (1)
	Barstar-related [ 52038] (1)
	Baseplate structural protein gp11 [ 56558] (1)
	Baseplate structural protein gp8 [ 89433] (1)
	Bcl-2 inhibitors of programmed cell death [ 56854] (1)
	Bcr-Abl oncoprotein oligomerization domain [ 69036] (1)
	Beta-D-glucan exohydrolase, C-terminal domain [ 52279] (1)
	Beta-galactosidase LacA, domain 3 [ 117100] (1)
	Beta-sheet designs [ 75790] (1)
	Bhpbr3, the Baff-binding loop of br3 embedded in a beta-hairpin peptide [ 82993] (1)
	Blood clotting [ 58188] (1)
	Blood coagulation inhibitor (disintegrin) [ 57552] (1)
	BolA-like [ 82657] (1)
	Bowman-Birk inhibitor, BBI [ 57247] (1)
	Box B RNA-binding N peptide [ 58339] (1)
	Bradykinin [ 58513] (1)
	Bromelain inhibitor VI (cysteine protease inhibitor) [ 57243] (1)
	Bromodomain [ 47370] (1)
	Bubble protein [ 103565] (1)
	beta-Catenine bound non-globular protein regions [ 58754] (1)
	beta-Galactosidase/glucuronidase domain [ 49303] (1)
	beta-Roll [ 51120] (1)
	beta-carbonic anhydrase, cab [ 53056] (1)
	beta-catenin-interacting protein ICAT [ 81730] (1)
	beta-hairpin design [ 64693] (1)
	beta-lactamase-inhibitor protein, BLIP [ 55648] (1)
	beta-sandwich domain of Sec23/24 [ 81995] (1)

C

Superfamily	Description [Sunid] (#Children)
Prefixed with C	Concanavalin A-like lectins/glucanases [ 49899] (25)
	Cysteine proteinases [ 54001] (22)
	Clavaminate synthase-like [ 51197] (13)
	Composite domain of metallo-dependent hydrolases [ 51338] (11)
	Class I glutamine amidotransferase-like [ 52317] (9)
	C-type lectin-like [ 56436] (8)
	Cytochrome c [ 46626] (8)
	CheY-like [ 52172] (7)
	Conotoxins [ 58465] (7)
	Cupredoxins [ 49503] (7)
	Cystine-knot cytokines [ 57501] (7)
	Cystatin/monellin [ 54403] (6)
	Cytidine deaminase-like [ 53927] (5)
	Chorismate mutase II [ 48600] (4)
	Class II aaRS and biotin synthetases [ 55681] (4)
	ClpP/crotonase [ 52096] (4)
	Cobalamin (vitamin B12)-dependent enzymes [ 51703] (4)
	Cyclophilin-like [ 50891] (4)
	Cyclotides [ 57038] (4)
	C-terminal domain of transcriptional repressors [ 50037] (3)
	C-terminal effector domain of the bipartite response regulators [ 46894] (3)
	CBD9-like [ 49344] (3)
	CNF1/YfiH-like putative cysteine hydrolases [ 64438] (3)
	Calcium-dependent phosphotriesterase [ 63829] (3)
	Carbamate kinase-like [ 53633] (3)
	Carbohydrate-binding domain [ 49384] (3)
	Cell growth inhibitor/plasmid maintenance toxic component [ 50118] (3)
	Chelatase [ 53800] (3)
	Chorismate lyase-like [ 64288] (3)
	Chromo domain-like [ 54160] (3)
	Clathrin adaptor appendage domain [ 49348] (3)
	CoA-dependent acyltransferases [ 52777] (3)
	Cyclin-like [ 47954] (3)
	Cysteine-rich domain [ 57889] (3)
	cAMP-binding domain-like [ 51206] (3)
	C2 domain (Calcium/lipid-binding domain, CaLB) [ 49562] (2)
	CAD & PB1 domains [ 54277] (2)
	CYTH-like phosphatases [ 55154] (2)
	Cadherin-like [ 49313] (2)
	Carbohydrate phosphatase [ 56655] (2)
	Carbon-nitrogen hydrolase [ 56317] (2)
	Carboxypeptidase regulatory domain-like [ 49464] (2)
	Caspase-like [ 52129] (2)
	Chondroitin AC/alginate lyase [ 48230] (2)
	Class II aaRS ABD-related [ 52954] (2)
	ClpS-like [ 54736] (2)
	Cobalamin adenosyltransferase-like [ 89028] (2)
	Colicin D/E5 nuclease domain [ 102824] (2)
	Conantokin [ 58495] (2)
	Crisp domain-like [ 57546] (2)
	Cullin repeat-like [ 74788] (2)
	Cysteine alpha-hairpin motif [ 47072] (2)
	Cytochrome b5-like heme/steroid binding domain [ 55856] (2)
	Cytochromes [ 47175] (2)
	Cytokine [ 50353] (2)
	Cytolysin/lectin [ 63724] (2)
	3-carboxy-cis,cis-mucoante lactonizing enzyme [ 75011] (1)
	C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase [ 51004] (1)
	C-terminal UvrC-binding domain of UvrB [ 46600] (1)
	C-terminal autoproteolytic domain of nucleoporin nup98 [ 82215] (1)
	C-terminal domain of B transposition protein [ 47681] (1)
	C-terminal domain of DFF45/ICAD (DFF-C domain) [ 81783] (1)
	C-terminal domain of Ku80 [ 101420] (1)
	C-terminal domain of PLC-beta [ 69989] (1)
	C-terminal domain of ProRS [ 64586] (1)
	C-terminal domain of RNA polymerase alpha subunit [ 47789] (1)
	C-terminal domain of adenylylcyclase associated protein [ 69340] (1)
	C-terminal domain of alpha and beta subunits of F1 ATP synthase [ 47917] (1)
	C-terminal domain of arginine repressor [ 55252] (1)
	C-terminal domain of mollusc hemocyanin [ 81277] (1)
	C-terminal fragment of thermolysin [ 63388] (1)
	C-terminal, gelsolin-like domain of Sec23/24 [ 82754] (1)
	CAC2185-like [ 142795] (1)
	CAPPD, an extracellular domain of amyloid beta A4 protein [ 109843] (1)
	CATH [ -7] (1)
	CBS-domain pair [ 54631] (1)
	CCCH zinc finger [ 90229] (1)
	CCHHC domain [ 103637] (1)
	CD4 and CD8 receptor regions [ 58636] (1)
	CHY zinc finger-like [ 161219] (1)
	CI-2 family of serine protease inhibitors [ 54654] (1)
	CO dehydrogenase ISP C-domain like [ 47741] (1)
	CO dehydrogenase flavoprotein C-terminal domain-like [ 55447] (1)
	CO dehydrogenase molybdoprotein N-domain-like [ 54665] (1)
	CPE0013-like [ 160148] (1)
	CRAL/TRIO N-terminal domain [ 46938] (1)
	CRAL/TRIO domain [ 52087] (1)
	CRISPR-associated protein [ 117987] (1)
	CSL zinc finger [ 144217] (1)
	CV3147-like [ 160991] (1)
	Cag-Z [ 109839] (1)
	CalX-like [ 141072] (1)
	Calcium ATPase, transduction domain A [ 81653] (1)
	Calcium ATPase, transmembrane domain M [ 81665] (1)
	Calcium-mediated lectin [ 82026] (1)
	Calcyclin-binding protein-like [ 140106] (1)
	Calmodulin [ 58908] (1)
	Calpain large subunit, middle domain (domain III) [ 49758] (1)
	Calponin-homology domain, CH-domain [ 47576] (1)
	Cannabinoid receptor 1 (CB1) fragment [ 83008] (1)
	Cap-Gly domain [ 74924] (1)
	Capsid protein major homology region peptide analog [ 58630] (1)
	CarD-like [ 141259] (1)
	Carbamoyl phosphate synthetase, large subunit connection domain [ 48108] (1)
	Carbamoyl phosphate synthetase, small subunit N-terminal domain [ 52021] (1)
	Carbohydrate binding domain [ 51055] (1)
	Carbonic anhydrase [ 51069] (1)
	Carboxypeptidase A prodomain-based design [ 103790] (1)
	Carboxypeptidase inhibitor [ 57620] (1)
	Casein kinase II beta subunit [ 57798] (1)
	Catestatin fragment from chromogranin A [ 75762] (1)
	Cation efflux protein cytoplasmic domain-like [ 160240] (1)
	Cation efflux protein transmembrane domain-like [ 161111] (1)
	CbiD-like [ 111342] (1)
	CbiG N-terminal domain-like [ 159672] (1)
	CcmK-like [ 143414] (1)
	CdCA1 repeat-like [ 159779] (1)
	Cdc48 domain 2-like [ 54585] (1)
	Cell cycle regulatory proteins [ 55637] (1)
	Cell division protein MinE topological specificity domain [ 55229] (1)
	Cell division protein ZapA-like [ 102829] (1)
	Cell wall binding repeat [ 69360] (1)
	Cell-division inhibitor MinC, C-terminal domain [ 63848] (1)
	Cell-division inhibitor MinC, N-terminal domain [ 64043] (1)
	Cell-division protein ZipA, C-terminal domain [ 64383] (1)
	Cellulose docking domain, dockering [ 64571] (1)
	Cellulose-binding domain [ 57180] (1)
	Cgl1923-like [ 159659] (1)
	ChaB-like [ 140376] (1)
	Chalcone isomerase [ 54626] (1)
	Chaperone J-domain [ 46565] (1)
	CheC-like [ 103039] (1)
	CheW-like [ 50341] (1)
	CheY-binding domain of CheA [ 55052] (1)
	Chemosensory protein Csp2 [ 100910] (1)
	Chemotaxis phosphatase CheZ [ 75708] (1)
	Chemotaxis receptor methyltransferase CheR, N-terminal domain [ 47757] (1)
	Chicken cartilage matrix protein [ 58002] (1)
	Chitinase insertion domain [ 54556] (1)
	Chlorophyll a-b binding protein [ 103511] (1)
	Cholecystokinin A receptor, N-domain [ 57642] (1)
	Cholecystokinin receptor fragments [ 64649] (1)
	Chorismate synthase, AroC [ 103263] (1)
	Chromosomal protein MC1 [ 102875] (1)
	CinA-like [ 142433] (1)
	Citrate synthase [ 48256] (1)
	Class II MHC-associated invariant chain ectoplasmic trimerization domain [ 48305] (1)
	Clathrin heavy-chain terminal domain [ 50989] (1)
	Clc chloride channel [ 81340] (1)
	Cloacin translocation domain [ 69369] (1)
	Cloroperoxidase [ 47571] (1)
	Clostridium neurotoxins, "coiled-coil" domain [ 58091] (1)
	Cna protein B-type domain [ 49478] (1)
	CoA-transferase family III (CaiB/BaiF) [ 89796] (1)
	CoaB-like [ 102645] (1)
	Coagulation factor VIII, membrane-binding peptide [ 58369] (1)
	Coat protein-binding domain of bacteriophage P22 scaffolding protein [ 58688] (1)
	CobE/GbiG C-terminal domain-like [ 159664] (1)
	Cobalamin (vitamin B12)-binding domain [ 52242] (1)
	CofD-like [ 142338] (1)
	CofE-like [ 144010] (1)
	Coiled serine [ 58813] (1)
	Coiled-coil dimerization domain from cortexillin I [ 58018] (1)
	Coiled-coil domain of nucleotide exchange factor GrpE [ 58014] (1)
	Colicin [ 56837] (1)
	Colicin D immunity protein [ 101125] (1)
	Colicin E immunity proteins [ 47345] (1)
	Colicin E3 immunity protein [ 54552] (1)
	Colicin E3 receptor domain [ 69985] (1)
	Colicin Ia, N-terminal domain [ 58096] (1)
	Colipase-like [ 57190] (1)
	Collagen fibre [ 144297] (1)
	Collagen-binding domain [ 89260] (1)
	Collagen-like peptides [ 58806] (1)
	ComB-like [ 142823] (1)
	Complement control module/SCR domain [ 57535] (1)
	Compstatin [ 58438] (1)
	Computational models partly based on experimental data [ 58199] (1)
	Connexin43 [ 118220] (1)
	Conserved core of transcriptional regulatory protein vp16 [ 56548] (1)
	Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 [ 47676] (1)
	Contryphan-R [ 58503] (1)
	Copper amine oxidase, domain N [ 55383] (1)
	Coproporphyrinogen III oxidase [ 102886] (1)
	CorA soluble domain-like [ 143865] (1)
	Core binding factor beta, CBF [ 50723] (1)
	Coronavirus NSP10-like [ 144246] (1)
	Coronavirus NSP7-like [ 140367] (1)
	Coronavirus NSP8-like [ 143076] (1)
	Coronavirus RNA-binding domain [ 110304] (1)
	Coronavirus S2 glycoprotein [ 111474] (1)
	Corticotropin releasing hormone [ 58385] (1)
	Crambin-like [ 57429] (1)
	Creatinase/aminopeptidase [ 55920] (1)
	Creatinase/prolidase N-terminal domain [ 53092] (1)
	Creatininase [ 102215] (1)
	Cro lambda fold design [ 144350] (1)
	Cross-reactive peptides from 60S acidic ribosomal protein p2 [ 103769] (1)
	Crustacean CHH/MIH/GIH neurohormone [ 81778] (1)
	Cryptochrome/photolyase FAD-binding domain [ 48173] (1)
	Cryptochrome/photolyase, N-terminal domain [ 52425] (1)
	CsrA-like [ 117130] (1)
	Ctag/Cox11 [ 110111] (1)
	Cu,Zn superoxide dismutase-like [ 49329] (1)
	Cullin homology domain [ 75632] (1)
	CutC-like [ 110395] (1)
	Cyanase C-terminal domain [ 55234] (1)
	Cyanovirin-N [ 51322] (1)
	Cysteine-rich DNA binding domain, (DM domain) [ 82927] (1)
	CytB endotoxin-like [ 55676] (1)
	Cytochrome P450 [ 48264] (1)
	Cytochrome b559 subunits [ 161045] (1)
	Cytochrome c oxidase subunit E [ 48479] (1)
	Cytochrome c oxidase subunit I-like [ 81442] (1)
	Cytochrome c oxidase subunit II-like, transmembrane region [ 81464] (1)
	Cytochrome c oxidase subunit III-like [ 81452] (1)
	Cytochrome c oxidase subunit h [ 47694] (1)
	Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor [ 81496] (1)
	Cytochrome f subunit of the cytochrome b6f complex, transmembrane anchor [ 103431] (1)
	Cytochrome f, large domain [ 49441] (1)
	cAMP and cGMP phosphodiesterase (PDE) fragments [ 58651] (1)
	clathrin assemblies [ 111485] (1)

D

Superfamily	Description [Sunid] (#Children)
Prefixed with D	Dimeric alpha+beta barrel [ 54909] (23)
	DHS-like NAD/FAD-binding domain [ 52467] (6)
	DNA-glycosylase [ 48150] (6)
	DNA/RNA polymerases [ 56672] (6)
	DEATH domain [ 47986] (4)
	DNA ligase/mRNA capping enzyme, catalytic domain [ 56091] (4)
	DNA-binding domain [ 54171] (4)
	Diaminopimelate epimerase-like [ 54506] (4)
	DinB/YfiT-like putative metalloenzymes [ 109854] (4)
	DNase I-like [ 56219] (3)
	Defensin-like [ 57392] (3)
	dsRNA-binding domain-like [ 54768] (3)
	DAK1/DegV-like [ 82549] (2)
	DHH phosphoesterases [ 64182] (2)
	DNA breaking-rejoining enzymes [ 56349] (2)
	DNA clamp [ 55979] (2)
	DNA methylase specificity domain [ 116734] (2)
	DNA primase core [ 56731] (2)
	DNA-binding pseudobarrel domain [ 101936] (2)
	Dehydroquinate synthase-like [ 56796] (2)
	Di-copper centre-containing domain [ 48056] (2)
	Dihydrofolate reductase-like [ 53597] (2)
	Dihydropteroate synthetase-like [ 51717] (2)
	DmpA/ArgJ-like [ 56266] (2)
	DsrEFH-like [ 75169] (2)
	Duplicated hybrid motif [ 51261] (2)
	1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain [ 69055] (1)
	D-aminoacid aminotransferase-like PLP-dependent enzymes [ 56752] (1)
	D-aminopeptidase, middle and C-terminal domains [ 50886] (1)
	D-lysine 5,6-aminomutase beta subunit KamE, N-terminal domain [ 117778] (1)
	D-ribose-5-phosphate isomerase (RpiA), lid domain [ 75445] (1)
	DBL homology domain (DH-domain) [ 48065] (1)
	DEK C-terminal domain [ 109715] (1)
	DLC [ 54648] (1)
	DNA damage-inducible protein DinI [ 54857] (1)
	DNA helicase RuvA subunit, C-terminal domain [ 46929] (1)
	DNA mismatch repair protein MutL [ 118116] (1)
	DNA polymerase III chi subunit [ 102400] (1)
	DNA polymerase III psi subunit [ 102220] (1)
	DNA polymerase III theta subunit-like [ 46575] (1)
	DNA polymerase beta, N-terminal domain-like [ 47802] (1)
	DNA primase DnaG, C-terminal domain [ 117023] (1)
	DNA repair protein MutS, domain I [ 55271] (1)
	DNA repair protein MutS, domain II [ 53150] (1)
	DNA repair protein MutS, domain III [ 48334] (1)
	DNA terminal protein [ 140919] (1)
	DNA topoisomerase I domain [ 55869] (1)
	DNA topoisomerase IV, alpha subunit [ 56726] (1)
	DNA-binding C-terminal domain of the transcription factor MotA [ 69652] (1)
	DNA-binding domain of EIN3-like [ 116768] (1)
	DNA-binding domain of Mlu1-box binding protein MBP1 [ 54616] (1)
	DNA-binding domain of intron-encoded endonucleases [ 64496] (1)
	DNA-binding domain of retroviral integrase [ 50122] (1)
	DNA-binding domains of HMG-I(Y) [ 58349] (1)
	DNA-binding protein LAG-1 (CSL) [ 110217] (1)
	DNA-binding protein Tfx [ 89915] (1)
	DOPA-like [ 143410] (1)
	DPP6 N-terminal domain-like [ 82171] (1)
	DPY module [ 90148] (1)
	DR1885-like metal-binding protein [ 110087] (1)
	DTD-like [ 69500] (1)
	DUSP-like [ 143791] (1)
	Dcp2 domain-like [ 140586] (1)
	Delta-sleep-inducing peptide immunoreactive peptide [ 58026] (1)
	DeoB insert domain-like [ 143856] (1)
	Designed EF-hand type cation-binding loop [ 111555] (1)
	Designed four-helix bundle protein [ 58833] (1)
	Designed heterodimeric coiled-coil [ 58823] (1)
	Designed single chain three-helix bundle [ 58840] (1)
	Designed trimeric coiled-coil [ 100904] (1)
	Dextranase, N-terminal domain [ 101596] (1)
	DhaL-like [ 101473] (1)
	Dhaf3308-like [ 159713] (1)
	Dimerisation domain of CENP-B [ 101160] (1)
	Dimerization cofactor of HNF-1 alpha [ 100957] (1)
	Dimerization motif of sir4 [ 90242] (1)
	Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit [ 47391] (1)
	Diol dehydratase, gamma subunit [ 47148] (1)
	Dipeptide transport protein [ 63992] (1)
	Dipeptidyl peptidase I (cathepsin C), exclusion domain [ 75001] (1)
	Diphtheria toxin, C-terminal domain [ 49380] (1)
	Diphtheria toxin, middle domain [ 56845] (1)
	DnaD domain-like [ 158499] (1)
	DnaJ/Hsp40 cysteine-rich domain [ 57938] (1)
	DnaK suppressor protein DksA, alpha-hairpin domain [ 109635] (1)
	Docking domain A of the erythromycin polyketide synthase (DEBS) [ 101166] (1)
	Docking domain B of the erythromycin polyketide synthase (DEBS) [ 101173] (1)
	Dodecin-like [ 89807] (1)
	Dom34/Pelota N-terminal domain-like [ 159065] (1)
	Domain from hypothetical 2610208m17rik protein [ 109779] (1)
	Domain of early E2A DNA-binding protein, ADDBP [ 47724] (1)
	Domain of poly(ADP-ribose) polymerase [ 47587] (1)
	Domain of the SRP/SRP receptor G-proteins [ 47364] (1)
	Double Clp-N motif [ 81923] (1)
	Double-stranded DNA-binding domain [ 46950] (1)
	Doublecortin (DC) [ 89837] (1)
	DsbB-like [ 158442] (1)
	DsbC/DsbG N-terminal domain-like [ 54423] (1)
	DsrC, the gamma subunit of dissimilatory sulfite reductase [ 69721] (1)
	Duffy binding domain-like [ 140924] (1)
	Dystroglycan, domain 2 [ 111006] (1)
	dUTPase-like [ 51283] (1)
	delta-Endotoxin (insectocide), N-terminal domain [ 56849] (1)
	delta-Endotoxin (insectocide), middle domain [ 51096] (1)
	delta-Toxin [ 58308] (1)

E

Superfamily	Description [Sunid] (#Children)
Prefixed with E	E set domains [ 81296] (23)
	EF-hand [ 47473] (11)
	EGF/Laminin [ 57196] (7)
	ENTH/VHS domain [ 48464] (4)
	Electron transport accessory proteins [ 50090] (4)
	EF-G C-terminal domain-like [ 54980] (3)
	Endosomal sorting complex assembly domain [ 140111] (3)
	EreA/ChaN-like [ 159501] (3)
	E2F-DP heterodimerization region [ 144074] (2)
	EPT/RTPC-like [ 55205] (2)
	EndoU-like [ 142877] (2)
	Enolase C-terminal domain-like [ 51604] (2)
	EspA/CesA-like [ 116927] (2)
	eIF4e-like [ 55418] (2)
	E2 regulatory, transactivation domain [ 51332] (1)
	E6 C-terminal domain-like [ 161229] (1)
	E7 C-terminal domain-like [ 161234] (1)
	EAL domain-like [ 141868] (1)
	EB1 dimerisation domain-like [ 140612] (1)
	ECOD [ -8] (1)
	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain [ 50465] (1)
	EF2458-like [ 140404] (1)
	EF2947-like [ 140607] (1)
	ENT-like [ 158639] (1)
	ENV polyprotein, receptor-binding domain [ 49830] (1)
	ERH-like [ 143875] (1)
	ERO1-like [ 110019] (1)
	ERP29 C domain-like [ 47933] (1)
	EV matrix protein [ 50012] (1)
	Ecotin, trypsin inhibitor [ 49772] (1)
	Ectatomin subunits [ 47401] (1)
	Eea1 homodimerisation domain [ 69979] (1)
	Efb C-domain-like [ 158366] (1)
	Eferin C-derminal domain-like [ 144270] (1)
	Elafin-like [ 57256] (1)
	Electron transport chains [ 58147] (1)
	Elongation factor TFIIS domain 2 [ 46942] (1)
	Elongation factor Ts (EF-Ts), dimerisation domain [ 54713] (1)
	Endothelin-like [ 58450] (1)
	Enolase N-terminal domain-like [ 54826] (1)
	Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain [ 47831] (1)
	Enzyme IIa from lactose specific PTS, IIa-lac [ 46973] (1)
	Ep-cadherin [ 103682] (1)
	Epsilon subunit of F1F0-ATP synthase C-terminal domain [ 46604] (1)
	Epsilon subunit of F1F0-ATP synthase N-terminal domain [ 51344] (1)
	Epsilon subunit of mitochondrial F1F0-ATP synthase [ 48690] (1)
	Erythropoietin (EPO) mimetic peptides [ 58893] (1)
	EscU C-terminal domain-like [ 160544] (1)
	EspE N-terminal domain-like [ 160246] (1)
	EsxAB dimer-like [ 140453] (1)
	Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment [ 56741] (1)
	Eukaryotic DNA topoisomerase I, dispensable insert domain [ 46596] (1)
	Eukaryotic RPB5 N-terminal domain [ 53036] (1)
	Eukaryotic initiation factor 4f subunit eIF4g, eIF4e-binding domain [ 101489] (1)
	Eukaryotic type KH-domain (KH-domain type I) [ 54791] (1)
	EutN/CcmL-like [ 159133] (1)
	Exotoxin A, middle domain [ 56864] (1)
	Expressed protein At2g23090/F21P24.15 [ 118359] (1)
	Extracellular hemoglobin linker subunit, receptor domain [ 141480] (1)
	Ezrin-radixin-moesin binding phosphoprotein 50 (ebp50) fragments [ 111539] (1)
	eEF-1beta-like [ 54984] (1)
	eEF1-gamma domain [ 89942] (1)
	eIF-2-alpha, C-terminal domain [ 110993] (1)
	eIF1-like [ 55159] (1)
	eIF2alpha middle domain-like [ 116742] (1)

F

Superfamily	Description [Sunid] (#Children)
Prefixed with F	Ferritin-like [ 47240] (9)
	FAD/NAD(P)-binding domain [ 51905] (8)
	Flavoproteins [ 52218] (8)
	FAD-linked reductases, C-terminal domain [ 54373] (7)
	4Fe-4S ferredoxins [ 54862] (6)
	Ferredoxin reductase-like, C-terminal NADP-linked domain [ 52343] (5)
	FAD-binding/transporter-associated domain-like [ 56176] (4)
	FAD-linked oxidases, C-terminal domain [ 55103] (4)
	FMN-binding split barrel [ 50475] (4)
	FKBP-like [ 54534] (3)
	FYVE/PHD zinc finger [ 57903] (3)
	FabD/lysophospholipase-like [ 52151] (3)
	Families 57/38 glycoside transferase middle domain [ 88688] (3)
	Formate/glycerate dehydrogenase catalytic domain-like [ 52283] (3)
	2Fe-2S ferredoxin-like [ 54292] (2)
	FAD-linked oxidoreductase [ 51730] (2)
	FMN-dependent nitroreductase-like [ 55469] (2)
	FMT C-terminal domain-like [ 50486] (2)
	FYSH domain [ 89895] (2)
	Family A G protein-coupled receptor-like [ 81321] (2)
	Fe-S cluster assembly (FSCA) domain-like [ 117916] (2)
	Fibre shaft of virus attachment proteins [ 51225] (2)
	FnI-like domain [ 57603] (2)
	Folate-binding domain [ 103025] (2)
	Frataxin/Nqo15-like [ 55387] (2)
	FucI/AraA C-terminal domain-like [ 50443] (2)
	FucI/AraA N-terminal and middle domains [ 53743] (2)
	Fumarate reductase respiratory complex transmembrane subunits [ 81343] (2)
	F-box domain [ 81383] (1)
	F1 ATPase inhibitor, IF1, C-terminal domain [ 64602] (1)
	F1F0 ATP synthase subunit A [ 81336] (1)
	F1F0 ATP synthase subunit B, membrane domain [ 81573] (1)
	F1F0 ATP synthase subunit C [ 81333] (1)
	F420-dependent methylenetetrahydromethanopterin dehydrogenase (MTD) [ 102324] (1)
	FAD-dependent thiol oxidase [ 69000] (1)
	FAD/NAD-linked reductases, dimerisation (C-terminal) domain [ 55424] (1)
	FAH [ 56529] (1)
	FAS1 domain [ 82153] (1)
	FAT domain of focal adhesion kinase [ 68993] (1)
	FF domain [ 81698] (1)
	FGAM synthase PurL, linker domain [ 109736] (1)
	FHV B2 protein-like [ 140506] (1)
	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) [ 47212] (1)
	FLJ32549 C-terminal domain-like [ 160651] (1)
	FLJ32549 domain-like [ 158548] (1)
	FMN-linked oxidoreductases [ 51395] (1)
	Family 10 polysaccharide lyase [ 81853] (1)
	Fatty acid synthase [ 144302] (1)
	FdhE-like [ 144020] (1)
	Fe,Mn superoxide dismutase (SOD), C-terminal domain [ 54719] (1)
	Fe,Mn superoxide dismutase (SOD), N-terminal domain [ 46609] (1)
	Fe-only hydrogenase [ 53920] (1)
	Fe-only hydrogenase smaller subunit [ 48674] (1)
	Ferredoxin chloroplastic transit peptide [ 58556] (1)
	Ferredoxin thioredoxin reductase (FTR), catalytic beta chain [ 57662] (1)
	Fertilization protein [ 47082] (1)
	Fibrinogen C-terminal domain-like [ 56496] (1)
	Fibrinogen coiled-coil and central regions [ 58010] (1)
	Fibritin [ 58046] (1)
	Fibronectin type III [ 49265] (1)
	Fic-like [ 140931] (1)
	FimD N-terminal domain-like [ 141729] (1)
	FinO-like [ 48657] (1)
	FlaG-like [ 160214] (1)
	Flagellar export chaperone FliS [ 101116] (1)
	Flagellar hook protein flgE [ 117143] (1)
	Flagellar transcriptional activator FlhD [ 63592] (1)
	Flavivirus capsid protein C [ 101257] (1)
	FlgN-like [ 140566] (1)
	FlhC-like [ 160930] (1)
	FliG [ 48029] (1)
	FomD-like [ 159234] (1)
	Formate dehydrogenase/DMSO reductase, domains 1-3 [ 53706] (1)
	Formiminotransferase domain of formiminotransferase-cyclodeaminase. [ 55116] (1)
	Formin homology 2 domain (FH2 domain) [ 101447] (1)
	Formylmethanofuran:tetrahydromethanopterin formyltransferase [ 55112] (1)
	Formyltransferase [ 53328] (1)
	Fragments of TNF receptors [ 111534] (1)
	Fragments of apolipoproteins [ 58580] (1)
	Fragments of bowman-birk inhibitor [ 58575] (1)
	Fragments of the L-type calcium channel alpha subunit Cav.1 (dihydropyridine receptor) [ 58739] (1)
	Frizzled cysteine-rich domain [ 63501] (1)
	FtsH protease domain-like [ 140990] (1)
	Fucose-specific lectin [ 89372] (1)
	FumA C-terminal domain-like [ 117457] (1)
	Fumarylacetoacetate hydrolase, FAH, N-terminal domain [ 63433] (1)
	Functional domain of the splicing factor Prp18 [ 47938] (1)
	Fungal elicitin [ 48647] (1)
	Fungal immunomodulatory protein, FIP [ 101542] (1)
	FwdE-like [ 143555] (1)
	FxFG nucleoporin repeats [ 58749] (1)
	Fzo-like conserved region [ 111479] (1)
	flu NP-like [ 161003] (1)

G

Superfamily	Description [Sunid] (#Children)
Prefixed with G	Galactose-binding domain-like [ 49785] (32)
	Glucocorticoid receptor-like (DNA-binding domain) [ 57716] (18)
	Galactose mutarotase-like [ 74650] (11)
	Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [ 54593] (10)
	Glutathione synthetase ATP-binding domain-like [ 56059] (9)
	Glycoside hydrolase/deacetylase [ 88713] (8)
	GHMP Kinase, C-terminal domain [ 55060] (7)
	gamma-Crystallin-like [ 49695] (6)
	GlnB-like [ 54913] (5)
	Glutamine synthetase/guanido kinase [ 55931] (5)
	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain [ 55347] (5)
	Glycosyl hydrolase domain [ 51011] (5)
	GAF domain-like [ 55781] (4)
	GINS helical bundle-like [ 158573] (4)
	Globin-like [ 46458] (4)
	Group II dsDNA viruses VP [ 49749] (3)
	G protein-binding domain [ 103652] (2)
	GAD domain-like [ 55261] (2)
	GAT-like domain [ 89009] (2)
	GFP-like [ 54511] (2)
	GST C-terminal domain-like [ 47616] (2)
	GTPase activation domain, GAP [ 48350] (2)
	GatB/YqeY motif [ 89095] (2)
	GroEL apical domain-like [ 52029] (2)
	GroEL equatorial domain-like [ 48592] (2)
	GroEL-intermediate domain like [ 54849] (2)
	GroES-like [ 50129] (2)
	Gurmarin-like [ 57048] (2)
	GAS2 domain-like [ 143575] (1)
	GCM domain [ 90073] (1)
	GDNF receptor-like [ 110035] (1)
	GIY-YIG endonuclease [ 82771] (1)
	GK1464-like [ 143579] (1)
	GLA-domain [ 57630] (1)
	GMP synthetase C-terminal dimerisation domain [ 54810] (1)
	GRIP domain [ 101283] (1)
	GTF2I-like repeat [ 117773] (1)
	GTP cyclohydrolase I feedback regulatory protein, GFRP [ 69761] (1)
	GUN4-like [ 140869] (1)
	GYF domain [ 55277] (1)
	Galactose oxidase, central domain [ 50965] (1)
	Gam-like [ 161266] (1)
	Gametocyte protein Pfg27 [ 89162] (1)
	Gamma-glutamyl cyclotransferase-like [ 110857] (1)
	Ganglioside M2 (gm2) activator [ 63707] (1)
	GatD N-terminal domain-like [ 141300] (1)
	Gated mechanosensitive channel [ 81330] (1)
	GckA/TtuD-like [ 82544] (1)
	Gelsolin fragment (residues 150-169) [ 58610] (1)
	Geminin coiled-coil domain [ 111469] (1)
	General secretion pathway protein M, EpsM [ 103054] (1)
	Genome linked protein vpg [ 144331] (1)
	GlcG-like [ 143744] (1)
	GlpP-like [ 110391] (1)
	Glu-tRNAGln amidotransferase C subunit [ 141000] (1)
	Glucose permease domain IIB [ 55604] (1)
	Glutaminase/Asparaginase [ 53774] (1)
	Glutamine synthetase, N-terminal domain [ 54368] (1)
	Glutamyl tRNA-reductase catalytic, N-terminal domain [ 69742] (1)
	Glutamyl tRNA-reductase dimerization domain [ 69075] (1)
	Glycerate kinase I [ 110738] (1)
	Glycerol-3-phosphate (1)-acyltransferase [ 69593] (1)
	Glycogen synthesis protein GlgS [ 109747] (1)
	Glycolipid transfer protein, GLTP [ 110004] (1)
	Glycosyl hydrolases family 6, cellulases [ 51989] (1)
	Glytm1bzip [ 70054] (1)
	GntR ligand-binding domain-like [ 48008] (1)
	Granulin repeat [ 57277] (1)
	GreA transcript cleavage protein, N-terminal domain [ 46557] (1)
	GroE chaperon [ 69999] (1)
	GroES fragments [ 58646] (1)
	Group I dsDNA viruses [ 88648] (1)
	Group V grass pollen allergen [ 81736] (1)
	Growth factor receptor domain [ 57184] (1)
	GspK insert domain-like [ 158544] (1)
	Guanido kinase N-terminal domain [ 48034] (1)
	Guanosine diphospho-D-mannose pyrophosphorylase/mannose-6-phosphate isomerase linker domain [ 159283] (1)
	GyrA/ParC C-terminal domain-like [ 101904] (1)
	gene 59 helicase assembly protein [ 48493] (1)
	gp120 core [ 56502] (1)
	gp5 N-terminal domain-like [ 69255] (1)
	gp9 [ 50017] (1)
	gpW/gp25-like [ 160719] (1)

H

Superfamily	Description [Sunid] (#Children)
Prefixed with H	HAD-like [ 56784] (25)
	Homeodomain-like [ 46689] (19)
	His-Me finger endonucleases [ 54060] (6)
	Histidine-containing phosphotransfer domain, HPT domain [ 47226] (6)
	HD-domain/PDEase-like [ 109604] (5)
	Hedgehog/DD-peptidase [ 55166] (5)
	"Helical backbone" metal receptor [ 53807] (4)
	HIT-like [ 54197] (4)
	HRDC-like [ 47819] (4)
	HSP20-like chaperones [ 49764] (4)
	Heme oxygenase-like [ 48613] (4)
	Histone-fold [ 47113] (4)
	4-helical cytokines [ 47266] (3)
	Hairpin loop containing domain-like [ 57414] (3)
	Heme-dependent peroxidases [ 48113] (3)
	HIT/MYND zinc finger-like [ 144232] (2)
	Hedgehog/intein (Hint) domain [ 51294] (2)
	Heme iron utilization protein-like [ 144064] (2)
	Heme-dependent catalase-like [ 56634] (2)
	Homing endonucleases [ 55608] (2)
	HprK N-terminal domain-like [ 75138] (2)
	HybD-like [ 53163] (2)
	HydA/Nqo6-like [ 56770] (2)
	HydB/Nqo4-like [ 56762] (2)
	6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK [ 55083] (1)
	H-NS histone-like proteins [ 81273] (1)
	HAMP domain-like [ 158472] (1)
	HAND domain of the nucleosome remodeling ATPase ISWI [ 101224] (1)
	HBS1-like domain [ 109732] (1)
	HCP-like [ 81901] (1)
	HI0933 insert domain-like [ 160996] (1)
	HIN-2000 domain-like [ 159141] (1)
	HIPIP (high potential iron protein) [ 57652] (1)
	HIV integrase-binding domain [ 140576] (1)
	HIV-1 Nef protein fragments [ 58658] (1)
	HIV-1 REV fragments [ 58326] (1)
	HIV-1 VPU cytoplasmic domain [ 57647] (1)
	HIV-1 envelope gp120 protein fragments [ 58663] (1)
	HIV-1 gp41 fragments [ 70011] (1)
	HLH, helix-loop-helix DNA-binding domain [ 47459] (1)
	HMA, heavy metal-associated domain [ 55008] (1)
	HMG-box [ 47095] (1)
	HMG-box transcription factor 1 fragments [ 111524] (1)
	HP0062-like [ 158414] (1)
	HP0242-like [ 158752] (1)
	HP1531-like [ 140496] (1)
	HPr-like [ 55594] (1)
	HR1 repeat [ 46585] (1)
	HSC20 (HSCB), C-terminal oligomerisation domain [ 47144] (1)
	HSP33 redox switch-like [ 118352] (1)
	HSP40/DnaJ peptide-binding domain [ 49493] (1)
	HSP90 C-terminal domain [ 110942] (1)
	HTLV-1 peptide [ 58344] (1)
	Hcp1-like [ 141452] (1)
	Head and neck region of the ectodomain of NDV fusion glycoprotein [ 69922] (1)
	Head decoration protein D (gpD, major capsid protein D) [ 51274] (1)
	Head domain of nucleotide exchange factor GrpE [ 51064] (1)
	Head morphogenesis protein gp7 [ 90246] (1)
	Head-binding domain of phage P22 tailspike protein [ 51327] (1)
	Head-to-tail joining protein W, gpW [ 64210] (1)
	Heat shock protein 70kD (HSP70), C-terminal subdomain [ 100934] (1)
	Heat shock protein 70kD (HSP70), peptide-binding domain [ 100920] (1)
	Heat-stable enterotoxin (HSE) [ 58458] (1)
	Heat-stable enterotoxin B [ 57007] (1)
	Hect, E3 ligase catalytic domain [ 56204] (1)
	Helical domain of Sec23/24 [ 81811] (1)
	Helical scaffold and wing domains of SecA [ 81886] (1)
	Helicase [ 58136] (1)
	HemD-like [ 69618] (1)
	Heme chaperone CcmE [ 82093] (1)
	Heme-binding protein A (HasA) [ 54621] (1)
	Hemerythrin-like [ 47188] (1)
	Hemocyanin, N-terminal domain [ 48050] (1)
	Hemolysin expression modulating protein HHA [ 68989] (1)
	Hemolytic lectin CEL-III, C-terminal domain [ 111265] (1)
	Hemopexin-like domain [ 50923] (1)
	Heparin binding site of non collagenous domain I (nc1) of collagen facit xiv [ 58641] (1)
	Heparin-binding domain from vascular endothelial growth factor [ 57593] (1)
	Hepatitis B viral capsid (hbcag) [ 47852] (1)
	Hepatitis C virus N-terminal capsid protein fragment 2-45 [ 58668] (1)
	Her-1 [ 110014] (1)
	Hermes dimerisation domain [ 140996] (1)
	Herpes virus serine proteinase, assemblin [ 50789] (1)
	HesB-like domain [ 89360] (1)
	Heterotrimerisation domain of extracellular hemoglobin linker subunits [ 144276] (1)
	HisI-like [ 141734] (1)
	Histone H3 C-terminal fragment 130-135 [ 58713] (1)
	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain [ 82185] (1)
	HlyD-like secretion proteins [ 111369] (1)
	Holliday junction resolvase RusA [ 103084] (1)
	Homo-oligomeric flavin-containing Cys decarboxylases, HFCD [ 52507] (1)
	Homocysteine S-methyltransferase [ 82282] (1)
	Homodimeric domain of signal transducing histidine kinase [ 47384] (1)
	Hook domain [ 116907] (1)
	Hormone receptor domain [ 111418] (1)
	Hsp33 domain [ 64397] (1)
	Hsp90 co-chaperone CDC37 [ 101391] (1)
	Htr2 transmembrane domain-like [ 158212] (1)
	Human glutathione reductase (HGR) inhibitor [ 58703] (1)
	HupF/HypC-like [ 159127] (1)
	Hut operon positive regulatory protein HutP [ 111064] (1)
	Hyaluronate lyase-like, C-terminal domain [ 49863] (1)
	Hyaluronidase post-catalytic domain-like [ 140657] (1)
	Hybrid and chimeric proteins [ 58790] (1)
	Hydrophobin II, HfbII [ 101751] (1)
	Hypothetical membrane protein Ta0354, soluble domain [ 116858] (1)
	Hypothetical protein AF0491, middle domain [ 109728] (1)
	Hypothetical protein At3g22680 [ 109920] (1)
	Hypothetical protein D-63 [ 109801] (1)
	Hypothetical protein HI1480 [ 103277] (1)
	Hypothetical protein MG354 [ 110009] (1)
	Hypothetical protein MPN330 [ 116965] (1)
	Hypothetical protein MTH1184 [ 57821] (1)
	Hypothetical protein MTH1880 [ 75412] (1)
	Hypothetical protein MTH393 [ 101332] (1)
	Hypothetical protein MTH538 [ 52206] (1)
	Hypothetical protein MTH677 [ 110783] (1)
	Hypothetical protein MTH777 (MT0777) [ 75181] (1)
	Hypothetical protein MTH865 [ 69025] (1)
	Hypothetical protein PA1324 [ 117074] (1)
	Hypothetical protein PF0899 [ 111057] (1)
	Hypothetical protein PH1602 [ 103365] (1)
	Hypothetical protein SAV1430 [ 110836] (1)
	Hypothetical protein ST1625 [ 101424] (1)
	Hypothetical protein TM0160 [ 103256] (1)
	Hypothetical protein TM0875 [ 90064] (1)
	Hypothetical protein TM1070 [ 89232] (1)
	Hypothetical protein TT1725 [ 103007] (1)
	Hypothetical protein Ta0289 C-terminal domain [ 103623] (1)
	Hypothetical protein Ta1206 [ 102891] (1)
	Hypothetical protein VC0424 [ 89946] (1)
	Hypothetical protein YfhH [ 101697] (1)
	Hypothetical protein YgiW [ 101756] (1)
	Hypothetical protein YhaI [ 109915] (1)
	Hypothetical protein YjbJ [ 69047] (1)
	Hypothetical protein YjiA, C-terminal domain [ 90002] (1)
	Hypothetical protein Yml108w [ 89975] (1)
	Hypothetical protein YoaG [ 103063] (1)
	Hypothetical protein YojF [ 89442] (1)
	Hypothetical protein YqbG [ 116915] (1)
	Hypothetical protein YwqG [ 103032] (1)
	Hypothetical protein c14orf129, hspc210 [ 103107] (1)
	Hypothetical protein yfbM [ 111069] (1)
	helix-turn-helix motif [ 58878] (1)

I

Superfamily	Description [Sunid] (#Children)
Prefixed with I	Isocitrate/Isopropylmalate dehydrogenase-like [ 53659] (5)
	Immunoglobulin [ 48726] (4)
	ISP domain [ 50022] (3)
	ITPase-like [ 52972] (3)
	IHF-like DNA-binding proteins [ 47729] (2)
	Indolic compounds 2,3-dioxygenase-like [ 140959] (2)
	Insect toxins [ 58400] (2)
	Invertebrate chitin-binding proteins [ 57625] (2)
	2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain [ 110921] (1)
	I/LWEQ domain [ 109885] (1)
	ICP-like [ 141066] (1)
	IFN mimetic syr6 [ 75780] (1)
	IL-1 receptor type 1 antagonist peptide AF10847 [ 58898] (1)
	IP3 receptor type 1 binding core, domain 2 [ 100909] (1)
	ISP transmembrane anchor [ 81502] (1)
	ISY1 domain-like [ 140102] (1)
	IVS-encoded protein-like [ 158446] (1)
	Ilarvirus coat protein N-terminal fragment [ 118396] (1)
	IlvD/EDD N-terminal domain-like [ 143975] (1)
	ImmE5-like [ 143469] (1)
	Immunodominant region of protein G of BRSV [ 58508] (1)
	Immunoglobulin-binding domains [ 54358] (1)
	Immunoreceptor tyrosine kinase activation motif, ITAM [ 58693] (1)
	ImpE-like [ 144059] (1)
	In vitro evolution products [ 103780] (1)
	Inactivation gate of potassium and sodium channels [ 58359] (1)
	Indigoidine synthase A-like [ 110581] (1)
	Influenza hemagglutinin (stalk) [ 58064] (1)
	Influenza hemagglutinin fragments [ 64632] (1)
	Influenza virus matrix protein M1 [ 48145] (1)
	Inhibitor of apoptosis (IAP) repeat [ 57924] (1)
	Inhibitor of mammalian ribonucleotide reductase [ 58926] (1)
	Inhibitor of vertebrate lysozyme, Ivy [ 89872] (1)
	Initiation factor IF2/eIF5b, domain 3 [ 52156] (1)
	Inorganic pyrophosphatase [ 50324] (1)
	Inosine monophosphate dehydrogenase (IMPDH) [ 51412] (1)
	Inovirus (filamentous phage) major coat protein [ 57987] (1)
	Insect cysteine-rich antifreeze protein [ 51156] (1)
	Insect pheromone/odorant-binding proteins [ 47565] (1)
	Insert subdomain of RNA polymerase alpha subunit [ 56553] (1)
	Insulin-like [ 56994] (1)
	Integrin alpha N-terminal domain [ 69318] (1)
	Integrin beta tail domain [ 69687] (1)
	Integrin domains [ 69179] (1)
	Integrin fragments [ 58698] (1)
	Integrin-binding RGD peptide [ 64683] (1)
	Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain [ 48340] (1)
	Interleukin 8-like chemokines [ 54117] (1)
	Intermediate filament protein, coiled coil region [ 64593] (1)
	Invasin/intimin cell-adhesion fragments [ 49373] (1)
	Invasion protein A (SipA) , C-terminal actin binding domain [ 101312] (1)
	IpaD-like [ 140693] (1)
	IpsF-like [ 69765] (1)
	Iron-dependent repressor protein, dimerization domain [ 47979] (1)
	Iron-sulfur subunit of formate dehydrogenase N, transmembrane anchor [ 81597] (1)
	IscX-like [ 140319] (1)
	Isochorismatase-like hydrolases [ 52499] (1)
	Isolated insulin B-chain [ 58774] (1)

J

Superfamily	Description [Sunid] (#Children)
Prefixed with J	JAB1/MPN domain [ 102712] (1)
	Jann2411-like [ 160904] (1)
	Jann4075-like [ 158587] (1)

K

Superfamily	Description [Sunid] (#Children)
Prefixed with K	KA1-like [ 103243] (2)
	KaiA/RbsU domain [ 101215] (2)
	Kazal-type serine protease inhibitors [ 100895] (2)
	Kinetochore globular domain [ 143026] (2)
	Kringle-like [ 57440] (2)
	14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) [ 81524] (1)
	39 kda initiator binding protein, IBP39, C-terminal domains [ 103409] (1)
	KRAB domain (Kruppel-associated box) [ 109640] (1)
	Kelch motif [ 117281] (1)
	Killer toxin KP6 alpha-subunit [ 55056] (1)
	Kinase-associated protein B-like [ 141251] (1)
	Kix domain of CBP (creb binding protein) [ 47040] (1)
	KorB DNA-binding domain-like [ 109709] (1)

L

Superfamily	Description [Sunid] (#Children)
Prefixed with L	lambda repressor-like DNA-binding domains [ 47413] (13)
	Lysozyme-like [ 53955] (11)
	Lipocalins [ 50814] (9)
	L domain-like [ 52058] (8)
	LigT-like [ 55144] (4)
	L30e-like [ 55315] (3)
	Lantibiotic peptides [ 58244] (3)
	LeuD/IlvD-like [ 52016] (3)
	Ligand-binding domain in the NO signalling and Golgi transport [ 111126] (3)
	Lipase/lipooxygenase domain (PLAT/LH2 domain) [ 49723] (3)
	L-aspartase-like [ 48557] (2)
	L28p-like [ 143800] (2)
	L9 N-domain-like [ 55658] (2)
	LDH C-terminal domain-like [ 56327] (2)
	Leech antihemostatic proteins [ 57262] (2)
	Leukocidin-like [ 56959] (2)
	LexA/Signal peptidase [ 51306] (2)
	Lipoxigenase [ 48484] (2)
	LuxS/MPP-like metallohydrolase [ 63411] (2)
	L,D-transpeptidase catalytic domain-like [ 141523] (1)
	L,D-transpeptidase pre-catalytic domain-like [ 143985] (1)
	L-A virus major coat protein [ 82856] (1)
	L-sulfolactate dehydrogenase-like [ 89733] (1)
	L21p-like [ 141091] (1)
	L27 domain [ 101288] (1)
	L35p-like [ 143034] (1)
	LCCL domain [ 69848] (1)
	LD-carboxypeptidase A C-terminal domain-like [ 141986] (1)
	LDL receptor-like module [ 57424] (1)
	LEA14-like [ 117070] (1)
	LEM domain [ 63451] (1)
	Lag-3 N-terminal region [ 158851] (1)
	Lamin A/C globular tail domain [ 74853] (1)
	LanC-like [ 158745] (1)
	LemA-like [ 140478] (1)
	Lesion bypass DNA polymerase (Y-family), little finger domain [ 100879] (1)
	Leucine zipper domain [ 57959] (1)
	Leucocin-like bacteriocin [ 100899] (1)
	Leukotriene A4 hydrolase N-terminal domain [ 63737] (1)
	LigA subunit of an aromatic-ring-opening dioxygenase LigAB [ 48076] (1)
	LigB-like [ 53213] (1)
	Light-harvesting complex subunits [ 56918] (1)
	Lipase chaperone-like [ 158855] (1)
	Liposaccharide-binding protein CAP18 (residues 106-137) [ 58390] (1)
	Lipovitellin-phosvitin complex, superhelical domain [ 48431] (1)
	Lipovitellin-phosvitin complex; beta-sheet shell regions [ 56968] (1)
	Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain [ 109925] (1)
	LmbE-like [ 102588] (1)
	Lp2179-like [ 160800] (1)
	Lumazine synthase [ 52121] (1)
	LysM domain [ 54106] (1)
	lambda integrase-like, N-terminal domain [ 47823] (1)

M

Superfamily	Description [Sunid] (#Children)
Prefixed with M	Metallo-dependent hydrolases [ 51556] (18)
	Metalloproteases ("zincins"), catalytic domain [ 55486] (17)
	Metallo-hydrolase/oxidoreductase [ 56281] (14)
	Metallo-dependent phosphatases [ 56300] (12)
	MoaD/ThiS [ 54285] (4)
	Mog1p/PsbP-like [ 55724] (4)
	Mss4-like [ 51316] (4)
	MOP-like [ 50331] (3)
	Methylglyoxal synthase-like [ 52335] (3)
	Microbial ribonucleases [ 53933] (3)
	Multiheme cytochromes [ 48695] (3)
	MCP/YpsA-like [ 102405] (2)
	MFS general substrate transporter [ 103473] (2)
	MTH1187/YkoF-like [ 89957] (2)
	Macro domain-like [ 52949] (2)
	Macrocyclic bacteriocins [ 58279] (2)
	Mediator hinge subcomplex-like [ 140718] (2)
	Membrane ion channel-forming peptide antibiotics containing D-aminoacids [ 58233] (2)
	Methionine synthase activation domain-like [ 56507] (2)
	Methyl-coenzyme M reductase subunits [ 55088] (2)
	Midkine [ 57288] (2)
	Molybdenum cofactor biosynthesis proteins [ 53218] (2)
	MurD-like peptide ligases, catalytic domain [ 53623] (2)
	MurD-like peptide ligases, peptide-binding domain [ 53244] (2)
	2-methylcitrate dehydratase PrpD [ 103378] (1)
	MAD protein fragments [ 111529] (1)
	MAL13P1.257-like [ 141678] (1)
	MAPEG domain-like [ 161084] (1)
	MAST3 pre-PK domain-like [ 140482] (1)
	MFPT repeat-like [ 141739] (1)
	MG296-like [ 158715] (1)
	MHC antigen-recognition domain [ 54452] (1)
	MIR domain [ 82109] (1)
	MIT domain [ 116846] (1)
	MIT domain-like [ 140361] (1)
	MK0786-like [ 143560] (1)
	MM3350-like [ 159941] (1)
	MOSC N-terminal domain-like [ 141673] (1)
	MPN010-like [ 144266] (1)
	MTH1598-like [ 69819] (1)
	MTH889-like [ 160363] (1)
	MTH938-like [ 64076] (1)
	MW0975(SA0943)-like [ 140423] (1)
	Magnesium transport protein CorA, transmembrane region [ 144083] (1)
	Mago nashi protein [ 89817] (1)
	Major capsid protein VP5 [ 103417] (1)
	Major capsid protein gp5 [ 56563] (1)
	Major surface antigen p30, SAG1 [ 74877] (1)
	MalF N-terminal region-like [ 160964] (1)
	Malate synthase G [ 51645] (1)
	Mannose 6-phosphate receptor domain [ 50911] (1)
	Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain [ 109775] (1)
	Mannose-binding lectins [ 51101] (1)
	Marinostatin, MstI [ 103764] (1)
	MbtH-like [ 160582] (1)
	Mechanosensitive channel protein MscS (YggB), C-terminal domain [ 82689] (1)
	Mechanosensitive channel protein MscS (YggB), transmembrane region [ 82861] (1)
	Membrane ion ATPase [ 82941] (1)
	Membrane penetration protein mu1 [ 69908] (1)
	Membrane-bound antimicrobial peptides [ 58443] (1)
	MesJ substrate recognition domain-like [ 82829] (1)
	MetI-like [ 161098] (1)
	Metal cation-transporting ATPase, ATP-binding domain N [ 81660] (1)
	Metal-binding peptide from MerP [ 103759] (1)
	Metalloporphyrin-binding designed peptides [ 90315] (1)
	Metallothionein [ 57868] (1)
	Methane monooxygenase hydrolase, gamma subunit [ 47152] (1)
	Methanol dehydrogenase subunit [ 48666] (1)
	Methenyltetrahydrofolate cyclohydrolase-like [ 101262] (1)
	Methenyltetrahydromethanopterin cyclohydrolase [ 56199] (1)
	Methionine synthase domain [ 47644] (1)
	Methionyl-tRNA synthetase (MetRS), Zn-domain [ 57770] (1)
	Methuselah ectodomain [ 63877] (1)
	Methyl-accepting chemotaxis protein (MCP) signaling domain [ 58104] (1)
	Methyl-coenzyme M reductase alpha and beta chain C-terminal domain [ 48081] (1)
	Methylamine dehydrogenase, L chain [ 57561] (1)
	Methylated DNA-protein cysteine methyltransferase domain [ 53155] (1)
	Methylated DNA-protein cysteine methyltransferase, C-terminal domain [ 46767] (1)
	Methylesterase CheB, C-terminal domain [ 52738] (1)
	MgtE N-terminal domain-like [ 158791] (1)
	MgtE membrane domain-like [ 161093] (1)
	Mib/herc2 domain-like [ 159034] (1)
	Microbial and mitochondrial ADK, insert "zinc finger" domain [ 57774] (1)
	Microcin leader peptide [ 58564] (1)
	Microtubule complexes [ 58194] (1)
	Mini-collagen I, C-terminal domain [ 103589] (1)
	Mitochondrial ATP synthase coupling factor 6 [ 111357] (1)
	Mitochondrial carrier [ 103506] (1)
	Mitochondrial cytochrome c oxidase subunit IV [ 81406] (1)
	Mitochondrial cytochrome c oxidase subunit VIIIb (aka IX) [ 81431] (1)
	Mitochondrial cytochrome c oxidase subunit VIIa [ 81419] (1)
	Mitochondrial cytochrome c oxidase subunit VIIb [ 81423] (1)
	Mitochondrial cytochrome c oxidase subunit VIIc (aka VIIIa) [ 81427] (1)
	Mitochondrial cytochrome c oxidase subunit VIa [ 81411] (1)
	Mitochondrial cytochrome c oxidase subunit VIc [ 81415] (1)
	Mitochondrial glycoprotein MAM33-like [ 54529] (1)
	Mitochondrial import receptor subunit Tom20 [ 47157] (1)
	Mitotic arrest deficient-like 1, Mad1 [ 75704] (1)
	MoaD-related protein, C-terminal domain [ 103239] (1)
	Mob1/phocein [ 101152] (1)
	MoeA C-terminal domain-like [ 63867] (1)
	MoeA N-terminal region -like [ 63882] (1)
	Moesin tail domain [ 48678] (1)
	Mollusk pheromone [ 90183] (1)
	Molybdenum cofactor biosynthesis protein C, MoaC [ 55040] (1)
	Molybdenum cofactor-binding domain [ 56003] (1)
	Molybdopterin synthase subunit MoaE [ 54690] (1)
	Monomethylamine methyltransferase MtmB [ 75098] (1)
	Monooxygenase (hydroxylase) regulatory protein [ 56029] (1)
	MtlR-like [ 158668] (1)
	MukF C-terminal domain-like [ 140570] (1)
	Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains [ 82714] (1)
	Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains [ 82693] (1)
	Multidrug efflux transporter AcrB transmembrane domain [ 82866] (1)
	Multidrug resistance ABC transporter [ 64607] (1)
	Multidrug resistance efflux transporter EmrE [ 103481] (1)
	Multimerization domain of the phosphoprotein from sendai virus [ 58034] (1)
	MurCD N-terminal domain [ 51984] (1)
	MurE/MurF N-terminal domain [ 63418] (1)
	Muscle protein complexes [ 64617] (1)
	MxiH-like [ 140129] (1)
	Myosin S1 fragment, N-terminal domain [ 50084] (1)
	Myosin phosphatase inhibitor 17kDa protein, CPI-17 [ 81790] (1)
	Myosin rod fragments [ 90257] (1)
	mRNA decapping enzyme DcpS N-terminal domain [ 102860] (1)
	mu transposase, C-terminal domain [ 50610] (1)

N

Superfamily	Description [Sunid] (#Children)
Prefixed with N	NTF2-like [ 54427] (30)
	Nucleotide-diphospho-sugar transferases [ 53448] (19)
	Nucleic acid-binding proteins [ 50249] (16)
	Nucleotidyltransferase [ 81301] (14)
	NAD(P)-binding Rossmann-fold domains [ 51735] (12)
	NagB/RpiA/CoA transferase-like [ 100950] (8)
	N-terminal nucleophile aminohydrolases (Ntn hydrolases) [ 56235] (7)
	Nudix [ 55811] (7)
	Nucleotidylyl transferase [ 52374] (5)
	Nucleotidyltransferase substrate binding subunit/domain [ 81593] (4)
	N-(deoxy)ribosyltransferase-like [ 52309] (3)
	Non-globular alpha+beta subunits of globular proteins [ 56568] (3)
	Nucleotide-binding domain [ 51971] (3)
	NusB-like [ 48013] (3)
	NAD kinase/diacylglycerol kinase-like [ 111331] (2)
	Nicotinate/Quinolinate PRTase C-terminal domain-like [ 51690] (2)
	Nicotinate/Quinolinate PRTase N-terminal domain-like [ 54675] (2)
	Nitrite/Sulfite reductase N-terminal domain-like [ 55124] (2)
	Nitrogenase accessory factor-like [ 53146] (2)
	NosL/MerB-like [ 160387] (2)
	Nucleocapsid protein dimerization domain [ 103068] (2)
	Nucleotide cyclase [ 55073] (2)
	5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain [ 55816] (1)
	N-acetylmuramoyl-L-alanine amidase-like [ 55846] (1)
	N-terminal Zn binding domain of HIV integrase [ 46919] (1)
	N-terminal coiled coil domain from apc [ 58050] (1)
	N-terminal domain of DnaB helicase [ 48024] (1)
	N-terminal domain of MutM-like DNA repair proteins [ 81624] (1)
	N-terminal domain of adenylylcyclase associated protein, CAP [ 101278] (1)
	N-terminal domain of alpha and beta subunits of F1 ATP synthase [ 50615] (1)
	N-terminal domain of bifunctional PutA protein [ 81935] (1)
	N-terminal domain of cbl (N-cbl) [ 47668] (1)
	N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 [ 55481] (1)
	N-terminal domain of the delta subunit of the F1F0-ATP synthase [ 47928] (1)
	N-terminal domains of the minor coat protein g3p [ 50176] (1)
	N-terminal fragment of gastric H/K-ATPase [ 82998] (1)
	N-terminal hairpin of ubiquitin (residues 1-17) [ 58779] (1)
	N-terminal, cytoplasmic domain of anti-sigmaE factor RseA [ 89069] (1)
	N-terminal, heterodimerisation domain of RBP7 (RpoE) [ 88798] (1)
	N-utilization substance G protein NusG, N-terminal domain [ 82679] (1)
	N-utilization substance G protein NusG, insert domain [ 82004] (1)
	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) [ 52255] (1)
	NAC domain [ 101941] (1)
	NAD(P)-linked oxidoreductase [ 51430] (1)
	NAD-binding domain of HMG-CoA reductase [ 55035] (1)
	NADH pyrophosphatase intervening domain [ 116738] (1)
	NAP-like [ 143113] (1)
	NE0471 N-terminal domain-like [ 143880] (1)
	NE1680-like [ 160766] (1)
	NEAT domain-like [ 158911] (1)
	NHL repeat [ 101898] (1)
	NIF3 (NGG1p interacting factor 3)-like [ 102705] (1)
	NMB0488-like [ 160207] (1)
	NMB0513-like [ 160472] (1)
	NOB1 zinc finger-like [ 144206] (1)
	NRDP1 C-terminal domain-like [ 160088] (1)
	NSFL1 (p97 ATPase) cofactor p47, SEP domain [ 102848] (1)
	NSP3 homodimer [ 69903] (1)
	NSP3A-like [ 159936] (1)
	NTR, cyclotide processing element [ 111517] (1)
	NadA-like [ 142754] (1)
	NblA-like [ 109859] (1)
	Necrosis inducing protein 1, NIP1 [ 103580] (1)
	Neurophysin II [ 49606] (1)
	Neurotoxin B-IV [ 57011] (1)
	Neurotoxin III (ATX III) [ 57419] (1)
	Neurotransmitter-gated ion-channel transmembrane pore [ 90112] (1)
	New fold designs [ 103775] (1)
	NfeD domain-like [ 141322] (1)
	Nickel-containing superoxide dismutase, NiSOD [ 109770] (1)
	Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) [ 52733] (1)
	Nicotinic receptor ligand binding domain-like [ 63712] (1)
	NifT/FixU-like [ 159203] (1)
	NinB [ 103370] (1)
	Nitric oxide (NO) synthase oxygenase domain [ 56512] (1)
	Nitrile hydratase alpha chain [ 56209] (1)
	Nitrite and sulphite reductase 4Fe-4S domain-like [ 56014] (1)
	Nitrous oxide reductase, N-terminal domain [ 50974] (1)
	Non-heme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) [ 81531] (1)
	Nonstructural protein ns2, Nep, M1-binding domain [ 101156] (1)
	Nop domain [ 89124] (1)
	Nop10-like SnoRNP [ 144210] (1)
	Notch domain [ 90193] (1)
	Nqo1 FMN-binding domain-like [ 142019] (1)
	Nqo1 middle domain-like [ 142984] (1)
	Nqo1C-terminal domain-like [ 140490] (1)
	Nqo5-like [ 143243] (1)
	Ns1 effector domain-like [ 143021] (1)
	Nuclear receptor coactivator Src-1 [ 48682] (1)
	Nuclear receptor coactivator interlocking domain [ 69125] (1)
	Nuclear receptor ligand-binding domain [ 48508] (1)
	Nuclease A inhibitor (NuiA) [ 82602] (1)
	Nucleoplasmin-like core domain [ 69203] (1)
	Nucleoporin domain [ 117289] (1)
	Nucleoside diphosphate kinase, NDK [ 54919] (1)
	Nucleoside hydrolase [ 53590] (1)
	Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain [ 47648] (1)
	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain [ 52418] (1)

O

Superfamily	Description [Sunid] (#Children)
Prefixed with O	Origin of replication-binding domain, RBD-like [ 55464] (5)
	omega toxin-like [ 57059] (5)
	OMPA-like [ 56925] (4)
	OMPT-like [ 69917] (2)
	OsmC-like [ 82784] (2)
	ORC1-binding domain [ 144005] (1)
	Obg GTP-binding protein C-terminal domain [ 102741] (1)
	Obg GTP-binding protein N-terminal domain [ 82051] (1)
	Octreotide (Sandostatine), a somatostatine analogue [ 58903] (1)
	Olfactory marker protein [ 63697] (1)
	Oligomerization domain of hepatitis delta antigen [ 58108] (1)
	Oligosaccharyltransferase subunit ost4p [ 103464] (1)
	Oligoxyloglucan reducing end-specific cellobiohydrolase [ 110296] (1)
	OmpA-like [ 103088] (1)
	OmpH-like [ 111384] (1)
	Oncogene products [ 50904] (1)
	Orange carotenoid protein, N-terminal domain [ 81930] (1)
	Orange domain-like [ 158457] (1)
	Ornithine decarboxylase C-terminal domain [ 55904] (1)
	Osmotin, thaumatin-like protein [ 49870] (1)
	Outer arm dynein light chain 1 [ 52075] (1)
	Outer capsid protein sigma 3 [ 64465] (1)
	Outer membrane efflux proteins (OEP) [ 56954] (1)
	Outer membrane lipoprotein [ 58042] (1)
	Outer membrane phospholipase A (OMPLA) [ 56931] (1)
	Outer surface protein [ 51087] (1)
	Outer surface protein C (OspC) [ 63515] (1)
	Oxidoreductase molybdopterin-binding domain [ 56524] (1)
	Oxygen-evolving enhancer protein 3, [ 101112] (1)
	Oxysterol-binding protein-like [ 144000] (1)
	occludin/ELL-like [ 144292] (1)

P

Superfamily	Description [Sunid] (#Children)
Prefixed with P	P-loop containing nucleoside triphosphate hydrolases [ 52540] (24)
	PH domain-like [ 50729] (13)
	PUA domain-like [ 88697] (13)
	6-phosphogluconate dehydrogenase C-terminal domain-like [ 48179] (12)
	Pectin lyase-like [ 51126] (11)
	PLP-dependent transferases [ 53383] (9)
	Positive stranded ssRNA viruses [ 88633] (9)
	PreATP-grasp domain [ 52440] (8)
	PYP-like sensor domain (PAS domain) [ 55785] (7)
	Pentein [ 55909] (7)
	Phosphoenolpyruvate/pyruvate domain [ 51621] (7)
	Pili subunits [ 54523] (7)
	Protein kinase-like (PK-like) [ 56112] (7)
	Putative DNA-binding domain [ 46955] (7)
	p53-like transcription factors [ 49417] (7)
	PDZ domain-like [ 50156] (6)
	(Phosphotyrosine protein) phosphatases II [ 52799] (5)
	PAP/OAS1 substrate-binding domain [ 81631] (5)
	PFL-like glycyl radical enzymes [ 51998] (5)
	Phage fibre proteins [ 69349] (5)
	Phospholipase D/nuclease [ 56024] (5)
	Pre-PUA domain [ 88802] (5)
	PRC-barrel domain [ 50346] (4)
	ParB/Sulfiredoxin [ 110849] (4)
	Porins [ 56935] (4)
	PriA/YqbF domain [ 160059] (4)
	Probable bacterial effector-binding domain [ 55136] (4)
	Prokaryotic SH3-related domain [ 82057] (4)
	Pseudouridine synthase [ 55120] (4)
	PLC-like phosphodiesterases [ 51695] (3)
	Periplasmic binding protein-like II [ 53850] (3)
	Phage tail proteins [ 69279] (3)
	Phosphoglycerate mutase-like [ 53254] (3)
	Phospholipase A2, PLA2 [ 48619] (3)
	Prim-pol domain [ 56747] (3)
	Prismane protein-like [ 56821] (3)
	Prokaryotic lipoproteins and lipoprotein localization factors [ 89392] (3)
	Protease propeptides/inhibitors [ 54897] (3)
	4'-phosphopantetheinyl transferase [ 56214] (2)
	PAP/Archaeal CCA-adding enzyme, C-terminal domain [ 55003] (2)
	PE/PPE dimer-like [ 140459] (2)
	PEBP-like [ 49777] (2)
	PEP carboxykinase-like [ 53795] (2)
	PGBD-like [ 47090] (2)
	PHM/PNGase F [ 49742] (2)
	PHP domain-like [ 89550] (2)
	PHP14-like [ 143724] (2)
	PIN domain-like [ 88723] (2)
	PK C-terminal domain-like [ 52935] (2)
	PK beta-barrel domain-like [ 50800] (2)
	PLP-binding barrel [ 51419] (2)
	POZ domain [ 54695] (2)
	PRTase-like [ 53271] (2)
	PTS system IIB component-like [ 52794] (2)
	PTS system fructose IIA component-like [ 53062] (2)
	PapD-like [ 49354] (2)
	Penicillin-binding protein associated domain [ 69189] (2)
	Peptidase/esterase 'gauge' domain [ 50993] (2)
	Phage tail protein-like [ 143749] (2)
	PheT/TilS domain [ 56037] (2)
	Phoshotransferase/anion transport protein [ 55804] (2)
	Phosphohistidine domain [ 52009] (2)
	Phospholipase C/P1 nuclease [ 48537] (2)
	PilZ domain-like [ 141371] (2)
	Plant lectins/antimicrobial peptides [ 57016] (2)
	Polo-box domain [ 82615] (2)
	PsbU/PolX domain-like [ 81585] (2)
	PurS-like [ 82697] (2)
	Pyruvoyl-dependent histidine and arginine decarboxylases [ 56271] (2)
	post-AAA+ oligomerization domain-like [ 48019] (2)
	post-HMGL domain-like [ 89000] (2)
	14-3-3 protein [ 48445] (1)
	P-domain of calnexin/calreticulin [ 63887] (1)
	P27(KIP1) fragment 22-106 [ 58673] (1)
	P40 nucleoprotein [ 101399] (1)
	PA domain [ 52025] (1)
	PA1123-like [ 160477] (1)
	PA1994-like [ 159275] (1)
	PA2021-like [ 141447] (1)
	PA2201 C-terminal domain-like [ 140731] (1)
	PA2201 N-terminal domain-like [ 140486] (1)
	PABC (PABP) domain [ 63570] (1)
	PAH2 domain [ 47762] (1)
	PAZ domain [ 101690] (1)
	PB2 C-terminal domain-like [ 160453] (1)
	PCD-like [ 55248] (1)
	PDB [ -9] (1)
	PEP carboxykinase N-terminal domain [ 68923] (1)
	PF0523-like [ 143870] (1)
	PG0775 C-terminal domain-like [ 158494] (1)
	PG0816-like [ 140753] (1)
	PG1388-like [ 160925] (1)
	PG1857-like [ 160448] (1)
	PH0156-like [ 160945] (1)
	PH0987 N-terminal domain-like [ 160467] (1)
	PH1570-like [ 159902] (1)
	PHL pollen allergen [ 49590] (1)
	PKD domain [ 49299] (1)
	PMP inhibitors [ 57283] (1)
	PMT central region-like [ 158842] (1)
	PP2C-like [ 81606] (1)
	PPK N-terminal domain-like [ 140356] (1)
	PR-1-like [ 55797] (1)
	PRP4-like [ 158230] (1)
	PSP1-like [ 58313] (1)
	PSPTO4464-like [ 158710] (1)
	PSTPO5379-like [ 160920] (1)
	PTPA-like [ 140984] (1)
	PTS IIb component [ 52728] (1)
	PTS-regulatory domain, PRD [ 63520] (1)
	PTSIIA/GutA-like [ 141530] (1)
	PUG domain-like [ 143503] (1)
	PW2, a tryptophan-rich anticocidial peptide [ 75797] (1)
	PWI domain [ 101233] (1)
	PX domain [ 64268] (1)
	Papillomavirus e6-interacting peptide of e6ap [ 58769] (1)
	Parathyroid hormone fragments (residues between 1 and 39) [ 58379] (1)
	Penaeidin-3a [ 103727] (1)
	Penicillin binding protein dimerisation domain [ 56519] (1)
	Penicillin-binding protein 2x (pbp-2x), c-terminal domain [ 54184] (1)
	Pentapeptide repeat-like [ 141571] (1)
	Pepsin inhibitor-3 [ 55149] (1)
	Peptide antagonists of IGF-1 [ 64688] (1)
	Peptide deformylase [ 56420] (1)
	Peptide derived from p-21 activated kinase [ 58723] (1)
	Peptide f (amphiphilic octadecapeptide) [ 58847] (1)
	Peptide hormones [ 58284] (1)
	Peptide methionine sulfoxide reductase [ 55068] (1)
	Peptidoglycan deacetylase N-terminal noncatalytic region [ 144015] (1)
	Peptidyl-tRNA hydrolase II [ 102462] (1)
	Peptidyl-tRNA hydrolase domain-like [ 110916] (1)
	Peptidyl-tRNA hydrolase-like [ 53178] (1)
	Peptidylarginine deiminase Pad4, middle domain [ 110083] (1)
	Perfringolysin [ 56978] (1)
	Peridinin-chlorophyll protein [ 48608] (1)
	Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex [ 47005] (1)
	Periplasmic binding protein-like I [ 53822] (1)
	Periplasmic chaperone C-domain [ 49584] (1)
	PetG subunit of the cytochrome b6f complex [ 103446] (1)
	PetL subunit of the cytochrome b6f complex [ 103436] (1)
	PetM subunit of the cytochrome b6f complex [ 103441] (1)
	PetN subunit of the cytochrome b6f complex [ 103451] (1)
	Phage replication organizer domain [ 140713] (1)
	Phase 1 flagellin [ 64518] (1)
	Phenylalanine zipper [ 109805] (1)
	Pheromone ER-23 [ 69964] (1)
	Pheromone-binding domain of LuxR-like quorum-sensing transcription factors [ 75516] (1)
	PhnH-like [ 159709] (1)
	PhoU-like [ 109755] (1)
	Phosphocholine cytidylyltransferase membrane-binding peptides [ 58374] (1)
	Phosphofructokinase [ 53784] (1)
	Phosphoglucomutase, C-terminal domain [ 55957] (1)
	Phosphoglucomutase, first 3 domains [ 53738] (1)
	Phosphoglycerate kinase [ 53748] (1)
	Phospholamban fragments [ 58569] (1)
	Phosphoprotein M1, C-terminal domain [ 118173] (1)
	Phosphoprotein XD domain [ 101089] (1)
	Phosphoprotein oligomerization domain-like [ 160892] (1)
	Phosphotyrosine protein phosphatases I [ 52788] (1)
	Photosystem I reaction center subunit X, PsaK [ 81563] (1)
	Photosystem I reaction center subunit XI, PsaL [ 81568] (1)
	Photosystem I subunit PsaD [ 64234] (1)
	Photosystem I subunits PsaA/PsaB [ 81558] (1)
	Photosystem II 10 kDa phosphoprotein PsbH [ 161025] (1)
	Photosystem II antenna protein-like [ 161077] (1)
	Photosystem II reaction center protein I, PsbI [ 161041] (1)
	Photosystem II reaction center protein J, PsbJ [ 161021] (1)
	Photosystem II reaction center protein K, PsbK [ 161037] (1)
	Photosystem II reaction center protein L, PsbL [ 161017] (1)
	Photosystem II reaction center protein M, PsbM [ 161033] (1)
	Photosystem II reaction center protein T, PsbT [ 161029] (1)
	Photosystem II reaction centre subunit H, transmembrane region [ 81490] (1)
	Photosystems [ 58156] (1)
	PhtA domain-like [ 142887] (1)
	Pilin fragments [ 58421] (1)
	Pituitary adenylate cyclase activating polypeptide, pacap21 [ 64644] (1)
	Plakin repeat [ 75399] (1)
	Plant inhibitors of proteinases and amylases [ 57027] (1)
	Plant invertase/pectin methylesterase inhibitor [ 101148] (1)
	Plant proteinase inhibitors [ 100897] (1)
	Plasmid maintenance system epsilon/zeta, antidote epsilon subunit [ 81710] (1)
	Plexin repeat [ 103575] (1)
	Plus3-like [ 159042] (1)
	Pollen allergen ole e 6 [ 111388] (1)
	Poly A polymerase C-terminal region-like [ 81891] (1)
	Poly(A) polymerase catalytic subunit-like [ 160957] (1)
	Polymorphic antigen SPAM-H1 (residues 90-127) [ 58395] (1)
	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 [ 46915] (1)
	Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain [ 54782] (1)
	Potassium channel toxins [ 75739] (1)
	Pre-protein crosslinking domain of SecA [ 81767] (1)
	Precorrin-8X methylmutase CbiC/CobH [ 63965] (1)
	Prefoldin [ 46579] (1)
	Prenyltransferase-like [ 143492] (1)
	Prepeptide of 5-ALAS [ 70028] (1)
	Preprotein translocase SecE subunit [ 103456] (1)
	Preprotein translocase SecY subunit [ 103491] (1)
	PriB N-terminal domain-like [ 140914] (1)
	Prion protein fragments [ 70038] (1)
	Prion-like [ 54098] (1)
	Probable ACP-binding domain of malonyl-CoA ACP transacylase [ 55048] (1)
	Probable GTPase Der, C-terminal domain [ 82653] (1)
	Profilin (actin-binding protein) [ 55770] (1)
	Programmed cell death protein 5 fragments [ 144336] (1)
	Proguanylin [ 89890] (1)
	Prokaryotic ribosomal protein L17 [ 64263] (1)
	Prokaryotic type I DNA topoisomerase [ 56712] (1)
	Prokaryotic type KH domain (KH-domain type II) [ 54814] (1)
	Proline pipe [ 58600] (1)
	Proline/betaine transporter ProP, C-terminal cytoplasmic domain [ 103661] (1)
	Proteasome activator [ 47216] (1)
	Protein A Ig(Fc)-binding domain mimics [ 58864] (1)
	Protein HNS-dependent expression A; HdeA [ 47752] (1)
	Protein prenylyltransferase [ 48439] (1)
	Protein serine/threonine phosphatase 2C, C-terminal domain [ 81601] (1)
	Protein-L-isoaspartyl O-methyltransferase, C-terminal domain [ 68930] (1)
	Proteinase A inhibitor IA3 [ 48686] (1)
	Proteins of incorrect, partial and unknown sequence [ 58208] (1)
	Proto-oncogene tyrosine-protein kinase lck CD4/CD8 interacting region [ 103749] (1)
	Proton glutamate symport protein [ 118215] (1)
	Protozoan pheromone proteins [ 47014] (1)
	PrpR receptor domain-like [ 159800] (1)
	PsbZ-like [ 161055] (1)
	Pseudo ankyrin repeat-like [ 140860] (1)
	PspA lactotransferrin-binding region [ 161270] (1)
	PurM C-terminal domain-like [ 56042] (1)
	PurM N-terminal domain-like [ 55326] (1)
	Purine and uridine phosphorylases [ 53167] (1)
	Purple acid phosphatase, N-terminal domain [ 49363] (1)
	Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) [ 101353] (1)
	Putative cyclase [ 102198] (1)
	Putative dsDNA mimic [ 102816] (1)
	Putative glucosidase YicI, C-terminal domain [ 117125] (1)
	Putative isomerase YbhE [ 101908] (1)
	Putative methyltransferase TM0872, insert domain [ 81799] (1)
	Putative modulator of DNA gyrase, PmbA/TldD [ 111283] (1)
	Putative transcriptional regulator TM1602, C-terminal domain [ 75500] (1)
	Pym (Within the bgcn gene intron protein, WIBG), N-terminal domain [ 101931] (1)
	Pyridoxine 5'-phosphate synthase [ 63892] (1)
	Pyrimidine nucleoside phosphorylase C-terminal domain [ 54680] (1)
	Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) [ 53182] (1)
	Pyruvate-ferredoxin oxidoreductase, PFOR, domain III [ 53323] (1)
	p53 tetramerization domain [ 47719] (1)
	pak1 autoregulatory domain [ 58729] (1)

Q

Superfamily	Description [Sunid] (#Children)
Prefixed with Q	QueA-like [ 111337] (1)
	Quinohemoprotein amine dehydrogenase A chain, domain 3 [ 69298] (1)
	Quinohemoprotein amine dehydrogenase C chain [ 69131] (1)
	Quinoprotein alcohol dehydrogenase-like [ 50998] (1)

R

Superfamily	Description [Sunid] (#Children)
Prefixed with R	Restriction endonuclease-like [ 52980] (33)
	RmlC-like cupins [ 51182] (24)
	Ribonuclease H-like [ 53098] (14)
	Ribosomal protein S5 domain 2-like [ 54211] (12)
	Ribbon-helix-helix [ 47598] (11)
	RuvA domain 2-like [ 47781] (7)
	RING/U-box [ 57850] (6)
	Retroviral matrix proteins [ 47836] (6)
	Ribulose-phoshate binding barrel [ 51366] (6)
	RNA-binding domain, RBD [ 54928] (5)
	Ribokinase-like [ 53613] (5)
	Rhodanese/Cell cycle control phosphatase [ 52821] (4)
	RNI-like [ 52047] (3)
	Rad51 N-terminal domain-like [ 47794] (3)
	Radical SAM enzymes [ 102114] (3)
	Riboflavin synthase domain-like [ 63380] (3)
	Ribosomal proteins S24e, L23 and L15e [ 54189] (3)
	Ribosome and ribosomal fragments [ 58119] (3)
	Ricin B-like lectins [ 50370] (3)
	Rubredoxin-like [ 57802] (3)
	RBP11-like subunits of RNA polymerase [ 55257] (2)
	RCC1/BLIP-II [ 50985] (2)
	RL5-like [ 55282] (2)
	RNA polymerase subunits [ 63393] (2)
	RNase III domain-like [ 69065] (2)
	RPB6/omega subunit-like [ 63562] (2)
	RelE-like [ 143011] (2)
	Reovirus inner layer core protein p3 [ 56831] (2)
	Retrovirus capsid dimerization domain-like [ 47353] (2)
	Rho N-terminal domain-like [ 68912] (2)
	Riboflavin kinase-like [ 82114] (2)
	Ribosomal L27 protein-like [ 110324] (2)
	Ribosomal protein L16p/L10e [ 54686] (2)
	Ribosomal protein L25-like [ 50715] (2)
	Ribosome inactivating proteins (RIP) [ 56371] (2)
	Rof/RNase P subunit-like [ 101744] (2)
	Rotavirus nonstructural proteins [ 58030] (2)
	Rudiment single hybrid motif [ 51246] (2)
	(2r)-phospho-3-sulfolactate synthase ComA [ 102110] (1)
	R1 subunit of ribonucleotide reductase, N-terminal domain [ 48168] (1)
	R3H domain [ 82708] (1)
	RAP domain-like [ 47045] (1)
	RGC domain-like [ 143885] (1)
	RILP dimerisation region [ 161256] (1)
	RNA 3'-terminal phosphate cyclase, RPTC, insert domain [ 52913] (1)
	RNA bacteriophage capsid protein [ 55405] (1)
	RNA polymerase [ 58181] (1)
	RNA polymerase subunit RPB10 [ 46924] (1)
	RNA-binding protein She2p [ 116942] (1)
	RNase A-like [ 54076] (1)
	ROP protein [ 47380] (1)
	RP71935 [ 58428] (1)
	RPA2825-like [ 158634] (1)
	RPB5-like RNA polymerase subunit [ 55287] (1)
	RSG-1.2 peptide [ 58330] (1)
	RUN domain-like [ 140741] (1)
	Rab geranylgeranyltransferase alpha-subunit, insert domain [ 49594] (1)
	Rabenosyn-5 Rab-binding domain-like [ 140125] (1)
	Rack1 interaction site of the CAMP-specific phosphodiesterase pde4d5. [ 70023] (1)
	Rad50 coiled-coil Zn hook [ 75712] (1)
	RalF, C-terminal domain [ 118104] (1)
	Ran binding protein zinc finger-like [ 90209] (1)
	Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain [ 69099] (1)
	Rap/Ran-GAP [ 111347] (1)
	Rap30/74 interaction domains [ 50916] (1)
	Ras GEF [ 48366] (1)
	RbcX-like [ 158615] (1)
	RbsD-like [ 102546] (1)
	Rbstp2229 protein [ 111171] (1)
	RecA protein, C-terminal domain [ 54752] (1)
	RecG, N-terminal domain [ 69008] (1)
	Receptor-binding domain of short tail fibre protein gp12 [ 88874] (1)
	Recombination endonuclease VII, C-terminal and dimerization domains [ 68918] (1)
	Recombination protein RecR [ 111304] (1)
	Regulator of G-protein signaling, RGS [ 48097] (1)
	Regulatory factor Nef [ 55671] (1)
	Regulatory protein AraC [ 51215] (1)
	RelB-like [ 141004] (1)
	Release factor [ 75620] (1)
	Reovirus components [ 58176] (1)
	Replicase NSP9 [ 101816] (1)
	Replication modulator SeqA, C-terminal DNA-binding domain [ 82808] (1)
	Replication terminator protein (Tus) [ 56596] (1)
	Replisome organizer (g39p helicase loader/inhibitor protein) [ 89064] (1)
	Resistin [ 111423] (1)
	Resolvase-like [ 53041] (1)
	Respiratory nitrate reductase 1 gamma chain [ 103501] (1)
	Retinoblastoma-associated protein RB1 fragments [ 144326] (1)
	Retro-GCN4 leucine zipper [ 58852] (1)
	Retrovirus capsid protein, N-terminal core domain [ 47943] (1)
	Retrovirus zinc finger-like domains [ 57756] (1)
	Rhabdovirus nucleoprotein-like [ 140809] (1)
	Rhomboid-like [ 144091] (1)
	RibA-like [ 142695] (1)
	Ribonuclease PH domain 2-like [ 55666] (1)
	Ribonuclease Rh-like [ 55895] (1)
	Ribonuclease domain of colicin E3 [ 63840] (1)
	Ribose/Galactose isomerase RpiB/AlsB [ 89623] (1)
	Ribosomal L11/L12e N-terminal domain [ 54747] (1)
	Ribosomal protein L1 [ 56808] (1)
	Ribosomal protein L10 [ 64659] (1)
	Ribosomal protein L10-like [ 160369] (1)
	Ribosomal protein L11, C-terminal domain [ 46906] (1)
	Ribosomal protein L13 [ 52161] (1)
	Ribosomal protein L14 [ 50193] (1)
	Ribosomal protein L19 (L19e) [ 48140] (1)
	Ribosomal protein L20 [ 74731] (1)
	Ribosomal protein L22 [ 54843] (1)
	Ribosomal protein L29 (L29p) [ 46561] (1)
	Ribosomal protein L30p/L7e [ 55129] (1)
	Ribosomal protein L31e [ 54575] (1)
	Ribosomal protein L32e [ 52042] (1)
	Ribosomal protein L34p [ 144321] (1)
	Ribosomal protein L36 [ 57840] (1)
	Ribosomal protein L39e [ 48662] (1)
	Ribosomal protein L4 [ 52166] (1)
	Ribosomal protein L6 [ 56053] (1)
	Ribosomal protein L7/12, oligomerisation (N-terminal) domain [ 48300] (1)
	Ribosomal protein L9 C-domain [ 55653] (1)
	Ribosomal protein S10 [ 54999] (1)
	Ribosomal protein S16 [ 54565] (1)
	Ribosomal protein S18 [ 46911] (1)
	Ribosomal protein S19 [ 54570] (1)
	Ribosomal protein S2 [ 52313] (1)
	Ribosomal protein S20 [ 46992] (1)
	Ribosomal protein S21p [ 161308] (1)
	Ribosomal protein S3 C-terminal domain [ 54821] (1)
	Ribosomal protein S6 [ 54995] (1)
	Ribosomal protein S7 [ 47973] (1)
	Ribosomal protein S8 [ 56047] (1)
	Ribosomal proteins L15p and L18e [ 52080] (1)
	Ribosome binding protein Y (YfiA homologue) [ 69754] (1)
	Ribosome recycling factor, RRF [ 55194] (1)
	Ribosome-binding factor A, RbfA [ 89919] (1)
	Right-handed coiled coil [ 58888] (1)
	Rnp2-like [ 160350] (1)
	Roadblock/LC7 domain [ 103196] (1)
	Rotavirus NSP2 fragment, C-terminal domain [ 75347] (1)
	Rotavirus NSP2 fragment, N-terminal domain [ 75574] (1)
	RplX-like [ 160374] (1)
	Rps17e-like [ 116820] (1)
	RraA-like [ 89562] (1)
	RuBisCO, large subunit, small (N-terminal) domain [ 54966] (1)
	RuBisCO, small subunit [ 55239] (1)
	RuBisCo LSMT C-terminal, substrate-binding domain [ 81822] (1)
	RuBisCo, C-terminal domain [ 51649] (1)
	Rv1873-like [ 140736] (1)
	Rv2632c-like [ 143212] (1)
	Rv2827c C-terminal domain-like [ 160887] (1)

S

Superfamily	Description [Sunid] (#Children)
Prefixed with S	S-adenosyl-L-methionine-dependent methyltransferases [ 53335] (57)
	SGNH hydrolase [ 52266] (9)
	Six-hairpin glycosidases [ 48208] (9)
	Sm-like ribonucleoproteins [ 50182] (6)
	Scorpion toxin-like [ 57095] (5)
	SCP-like [ 55718] (4)
	SMAD/FHA domain [ 49879] (4)
	SNARE-like [ 64356] (4)
	Saposin [ 47862] (4)
	ssDNA-binding transcriptional regulator domain [ 54447] (4)
	S13-like H2TH domain [ 46946] (3)
	S15/NS1 RNA-binding domain [ 47060] (3)
	SAICAR synthase-like [ 56104] (3)
	SAM/Pointed domain [ 47769] (3)
	SET domain [ 82199] (3)
	SIS domain [ 53697] (3)
	SPOC domain-like [ 100939] (3)
	Sensory domain-like [ 103190] (3)
	Sigma3 and sigma4 domains of RNA polymerase sigma factors [ 88659] (3)
	Snake toxin-like [ 57302] (3)
	Starch-binding domain-like [ 49452] (3)
	SufE/NifU [ 82649] (3)
	ssDNA viruses [ 88645] (3)
	S-adenosylmethionine decarboxylase [ 56276] (2)
	SAND domain-like [ 63763] (2)
	SRCR-like [ 56487] (2)
	STI-like [ 50386] (2)
	Scorpion toxin-based designs [ 58918] (2)
	Sec63 N-terminal domain-like [ 158702] (2)
	SecB-like [ 54611] (2)
	Serine metabolism enzymes domain [ 143548] (2)
	Serine protease inhibitors [ 57567] (2)
	Sialidases [ 50939] (2)
	SpoIIaa-like [ 52091] (2)
	SspB-like [ 101738] (2)
	Subdomain of clathrin and coatomer appendage domain [ 55711] (2)
	Subtilisin-like [ 52743] (2)
	Subunits of heterodimeric actin filament capping protein Capz [ 90096] (2)
	Synthetic high affinity IgE receptor antagonists [ 64704] (2)
	'SARS ORF9b-like [ 141666] (1)
	30S ribosomal protein THX [ 58322] (1)
	S-adenosylmethionine synthetase [ 55973] (1)
	SAP domain [ 68906] (1)
	SARS Nsp1-like [ 160099] (1)
	SARS receptor-binding domain-like [ 143587] (1)
	SBT domain [ 103612] (1)
	SEA domain [ 82671] (1)
	SH2 domain [ 55550] (1)
	SH3-domain [ 50044] (1)
	SMAD MH1 domain [ 56366] (1)
	SMI1/KNR4-like [ 160631] (1)
	SMR domain-like [ 160443] (1)
	SMc04008-like [ 158757] (1)
	SNARE fusion complex [ 58038] (1)
	SNF-like [ 161070] (1)
	SO1590-like [ 159238] (1)
	SO2669-like [ 158418] (1)
	SOCS box-like [ 158235] (1)
	SP0561-like [ 140683] (1)
	SP0830-like [ 160379] (1)
	SPy1572-like [ 140121] (1)
	SRF-like [ 55455] (1)
	SRP19 [ 69695] (1)
	SSO1389-like [ 160980] (1)
	SSo0622-like [ 111278] (1)
	STAT [ 47655] (1)
	STIV B116-like [ 143602] (1)
	SWIB/MDM2 domain [ 47592] (1)
	SacY-like RNA-binding domain [ 50151] (1)
	Sama2622-like [ 158675] (1)
	Satellite viruses [ 88650] (1)
	Satiety factor CART (cocaine and amphetamine regulated transcript) [ 64546] (1)
	Scaffolding protein gpD of bacteriophage procapsid [ 48045] (1)
	Sec-C motif [ 103642] (1)
	Sec-beta subunit [ 103460] (1)
	Sec1/munc18-like (SM) proteins [ 56815] (1)
	Sec2 N-terminal region [ 144284] (1)
	Sec7 domain [ 48425] (1)
	Second domain of FERM [ 47031] (1)
	Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor [ 49447] (1)
	Sema domain [ 101912] (1)
	Serpins [ 56574] (1)
	Serum albumin-like [ 48552] (1)
	Seven-hairpin glycosidases [ 48225] (1)
	Sheep myeloid antimicrobial peptide SMAP29 based peptides [ 75752] (1)
	Shew3726-like [ 160272] (1)
	Sigma2 domain of RNA polymerase sigma factors [ 88946] (1)
	Signal peptide-binding domain [ 47446] (1)
	Signal recognition particle (SRP) complex [ 103692] (1)
	Signal recognition particle alu RNA binding heterodimer, SRP9/14 [ 54762] (1)
	SinR repressor dimerisation domain-like [ 47406] (1)
	Single hybrid motif [ 51230] (1)
	SipA N-terminal domain-like [ 140746] (1)
	SirA-like [ 64307] (1)
	Siroheme synthase middle domains-like [ 75615] (1)
	Skp1 dimerisation domain-like [ 81382] (1)
	Smac/diablo [ 46984] (1)
	Smad-binding domain of Sara [ 58718] (1)
	Small protein B (SmpB) [ 74982] (1)
	Small subunit C-terminal inhibitory peptide of ribonucleotide reductase [ 58708] (1)
	Small-conductance potassium channel [ 81327] (1)
	Smc hinge domain [ 75553] (1)
	Smp-1-like [ 101601] (1)
	Smr-associated domain-like [ 158949] (1)
	Soluble domain of poliovirus core protein 3a [ 89043] (1)
	Soluble quinoprotein glucose dehydrogenase [ 50952] (1)
	Soluble secreted chemokine inhibitor, VCCI [ 49889] (1)
	Somatomedin B domain [ 90188] (1)
	SopE-like GEF domain [ 81832] (1)
	Sortase [ 63817] (1)
	Spectrin repeat [ 46966] (1)
	Spermadhesin, CUB domain [ 49854] (1)
	SpoVG-like [ 160537] (1)
	Sporulation inhibitor Sda [ 100985] (1)
	Sporulation related repeat [ 110997] (1)
	Sporulation response regulatory protein Spo0B [ 55890] (1)
	Stabilizer of iron transporter SufD [ 101960] (1)
	Staphylocoagulase [ 101094] (1)
	Staphylococcal nuclease [ 50199] (1)
	Staphylokinase/streptokinase [ 54328] (1)
	Stathmin [ 101494] (1)
	Substrate-binding domain of HMG-CoA reductase [ 56542] (1)
	Subtilisin inhibitor [ 55399] (1)
	Subunit III of photosystem I reaction centre, PsaF [ 81536] (1)
	Subunit IX of photosystem I reaction centre, PsaJ [ 81544] (1)
	Subunit PsaX of photosystem I reaction centre [ 81552] (1)
	Subunit VIII of photosystem I reaction centre, PsaI [ 81540] (1)
	Subunit X (non-heme 7 kDa protein) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) [ 81514] (1)
	Subunit XI (6.4 kDa protein) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) [ 81518] (1)
	Subunit XII of photosystem I reaction centre, PsaM [ 81548] (1)
	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain [ 46977] (1)
	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain [ 56425] (1)
	Succinyl-CoA synthetase domains [ 52210] (1)
	Sulfolobus fructose-1,6-bisphosphatase-like [ 111249] (1)
	Superantigen (mitogen) Ypm [ 101606] (1)
	Superantigen MAM [ 101344] (1)
	Superantigen toxins, C-terminal domain [ 54334] (1)
	Supernatant protein factor (SPF), C-terminal domain [ 101576] (1)
	Superoxide reductase-like [ 49367] (1)
	Suppressor of Fused, N-terminal domain [ 103359] (1)
	SurE-like [ 64167] (1)
	Surface presentation of antigens (SPOA) [ 101801] (1)
	Surp module (SWAP domain) [ 109905] (1)
	Swiveling domain of dehydratase reactivase alpha subunit [ 82317] (1)
	Synaptobrevin-II fragments [ 58759] (1)
	Syndecan-4 cytoplasmic domain [ 64639] (1)
	Synuclein [ 118375] (1)

T

Superfamily	Description [Sunid] (#Children)
Prefixed with T	Thioredoxin-like [ 52833] (23)
	(Trans)glycosidases [ 51445] (14)
	TPR-like [ 48452] (8)
	Thiamin diphosphate-binding fold (THDP-binding) [ 52518] (8)
	Thioesterase/thiol ester dehydrase-isomerase [ 54637] (8)
	Trimeric LpxA-like enzymes [ 51161] (8)
	Translation proteins SH3-like domain [ 50104] (7)
	Tautomerase/MIF [ 55331] (6)
	Translation proteins [ 50447] (6)
	Terpenoid synthases [ 48576] (5)
	Terpenoid cyclases/Protein prenyltransferases [ 48239] (4)
	Tetrahydrobiopterin biosynthesis enzymes-like [ 55620] (4)
	Trypsin-like serine proteases [ 50494] (4)
	Tudor/PWWP/MBT [ 63748] (4)
	tRNA-binding arm [ 46589] (4)
	THUMP domain-like [ 143437] (3)
	TIMP-like [ 50242] (3)
	TK C-terminal domain-like [ 52922] (3)
	TrpR-like [ 48295] (3)
	Type III secretion system domain [ 140591] (3)
	TATA-box binding protein-like [ 55945] (2)
	TGS-like [ 81271] (2)
	TNF receptor-like [ 57586] (2)
	TRAF domain-like [ 49599] (2)
	TRAP-like [ 51219] (2)
	TTHA0583/YokD-like [ 110710] (2)
	TTHA1013/TTHA0281-like [ 143100] (2)
	TerB-like [ 158682] (2)
	Thiolase-like [ 53901] (2)
	ThrRS/AlaRS common domain [ 55186] (2)
	TolA/TonB C-terminal domain [ 74653] (2)
	Translational machinery components [ 53137] (2)
	Transmembrane di-heme cytochromes [ 81342] (2)
	Triger factor/SurA peptide-binding domain-like [ 109998] (2)
	Troponin coil-coiled subunits [ 90250] (2)
	Tubby C-terminal domain-like [ 54518] (2)
	Type III secretory system chaperone-like [ 69635] (2)
	5' to 3' exonuclease, C-terminal subdomain [ 47807] (1)
	T-antigen specific domain-like [ 161240] (1)
	T4 endonuclease V [ 47077] (1)
	TAF(II)230 TBP-binding fragment [ 47055] (1)
	TAFH domain-like [ 158553] (1)
	TAT peptides [ 58334] (1)
	TAZ (CH) Zn-binding domain based design [ 75785] (1)
	TAZ domain [ 57933] (1)
	TB module/8-cys domain [ 57581] (1)
	TBP-binding domain of the transcription factor IIIb Brf1 subunit [ 90298] (1)
	TBP-interacting protein-like [ 159612] (1)
	TFB5-like [ 142897] (1)
	TH (toxin hand)-motif beta-sheet mini-protein designs [ 64674] (1)
	TM0693-like [ 140560] (1)
	TM0957-like [ 141318] (1)
	TM1457-like [ 118010] (1)
	TM1622-like [ 143477] (1)
	TM1631-like [ 117396] (1)
	TM1646-like [ 158397] (1)
	TMV-like viral coat proteins [ 47195] (1)
	TNF-like [ 49842] (1)
	TPR domain-based design [ 90308] (1)
	TRADD, N-terminal domain [ 55044] (1)
	TRCF domain-like [ 143517] (1)
	TROVE domain-like [ 140864] (1)
	TSP type-3 repeat [ 103647] (1)
	TSP-1 type 1 repeat [ 82895] (1)
	TSP9-like [ 144256] (1)
	TT1751-like [ 103247] (1)
	TTHA0068-like [ 140663] (1)
	TTHA1528-like [ 143592] (1)
	TTHC002-like [ 160761] (1)
	TTP0101/SSO1404-like [ 143430] (1)
	Ta0600-like [ 158436] (1)
	Ta1353-like [ 103165] (1)
	Tachylectin-2 [ 50934] (1)
	Taf5 N-terminal domain-like [ 160897] (1)
	Telomeric repeat binding factor (TRF) dimerisation domain [ 63600] (1)
	Tertiapin [ 58405] (1)
	Tetrabrachion [ 58054] (1)
	Tetracyclin repressor-like, C-terminal domain [ 48498] (1)
	Tetramerization domain of the Mnt repressor [ 58059] (1)
	Tetrapyrrole methylase [ 53790] (1)
	Tetraspanin [ 48652] (1)
	Tex N-terminal region-like [ 158832] (1)
	The spindle assembly checkpoint protein mad2 [ 56019] (1)
	Thermophilic metalloprotease-like [ 144052] (1)
	Thermostable heterotrimeric coiled coil [ 58828] (1)
	Thermostable phytase (3-phytase) [ 50956] (1)
	ThiG-like [ 110399] (1)
	Thiamin phosphate synthase [ 51391] (1)
	Thiamin pyrophosphokinase, catalytic domain [ 63999] (1)
	Thiamin pyrophosphokinase, substrate-binding domain [ 63862] (1)
	Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) [ 74863] (1)
	Thrombomodulin EGF domain fragment (residues 409-426) [ 58620] (1)
	Thymidylate synthase-complementing protein Thy1 [ 69796] (1)
	Thymidylate synthase/dCMP hydroxymethylase [ 55831] (1)
	Thyroglobulin type-1 domain [ 57610] (1)
	Tim10-like [ 144122] (1)
	Tlp20, baculovirus telokin-like protein [ 51289] (1)
	TmoB-like [ 110814] (1)
	TolB, C-terminal domain [ 50960] (1)
	TolB, N-terminal domain [ 52964] (1)
	Toll/Interleukin receptor TIR domain [ 52200] (1)
	Tombusvirus P19 core protein, VP19 [ 103145] (1)
	Topoisomerase V catalytic domain-like [ 140979] (1)
	Toprim domain [ 110455] (1)
	TorD-like [ 89155] (1)
	Tp47 lipoprotein, N-terminal domain [ 82220] (1)
	Tp47 lipoprotein, middle and C-terminal domains [ 81986] (1)
	TraM-like [ 140581] (1)
	Transactivation domain [ 74800] (1)
	Transactivation protein TAT [ 58594] (1)
	Transcription factor IIA (TFIIA), alpha-helical domain [ 47396] (1)
	Transcription factor IIA (TFIIA), beta-barrel domain [ 50784] (1)
	Transcription factor NusA, N-terminal domain [ 69705] (1)
	Transcription factor STAT-4 N-domain [ 48092] (1)
	Transcriptional repressor TraM [ 109631] (1)
	Transducin (alpha subunit), insertion domain [ 47895] (1)
	Transducin (heterotrimeric G protein), gamma chain [ 48670] (1)
	Transducin alpha-1 subunit rhodopsin binding domain (res. 340-350) [ 58678] (1)
	Transducin gamma-t1 subunit rhodopsin bound fragment (res. 60-71) [ 90291] (1)
	Transferrin receptor-like dimerisation domain [ 47672] (1)
	Transferrin receptor-transferrin complex [ 103687] (1)
	Transglutaminase, two C-terminal domains [ 49309] (1)
	Translation initiation factor 2 beta, aIF2beta, N-terminal domain [ 100966] (1)
	Translation initiation factor IF3, C-terminal domain [ 55200] (1)
	Translation initiation factor IF3, N-terminal domain [ 54364] (1)
	Translational regulator protein regA [ 55064] (1)
	Translin [ 74784] (1)
	Translocated intimin receptor (tir) intimin-binding domain [ 58734] (1)
	Transmembrane helical fragments [ 58518] (1)
	Transposase IS200-like [ 143422] (1)
	Transthyretin (synonym: prealbumin) [ 49472] (1)
	Trefoil [ 57492] (1)
	Tricorn protease N-terminal domain [ 69304] (1)
	Tricorn protease domain 2 [ 69322] (1)
	Trigger factor ribosome-binding domain [ 102735] (1)
	Trimeric adhesin [ 101999] (1)
	Trimerization domain of TRAF [ 57953] (1)
	Triosephosphate isomerase (TIM) [ 51351] (1)
	Triple coiled coil domain of C-type lectins [ 57944] (1)
	TrkA C-terminal domain-like [ 116726] (1)
	Trm112p-like [ 158997] (1)
	TrmB C-terminal domain-like [ 159071] (1)
	TrmE connector domain [ 116878] (1)
	Tropomyosin [ 57997] (1)
	Troponin I fragments [ 58415] (1)
	Trp-cage miniprotein [ 75770] (1)
	Trypsin inhibitor SFTIf-1 [ 64654] (1)
	Tryptophan synthase beta subunit-like PLP-dependent enzymes [ 53686] (1)
	Tsx-like channel [ 111364] (1)
	Tubulin C-terminal domain-like [ 55307] (1)
	Tubulin chaperone cofactor A [ 46988] (1)
	Tubulin nucleotide-binding domain-like [ 52490] (1)
	Tumor suppressor gene product Apc [ 82931] (1)
	Tumor suppressor p53 fragments [ 58744] (1)
	Tumor suppressor protein p19-ARF fragment [ 70043] (1)
	Type I dockerin domain [ 63446] (1)
	Type II 3-dehydroquinate dehydratase [ 52304] (1)
	Type II DNA topoisomerase [ 56719] (1)
	Type X cellulose binding domain, CBDX [ 57615] (1)
	Typo IV secretion system protein TraC [ 101082] (1)
	t-snare proteins [ 47661] (1)
	tRNA-guanine transglycosylase [ 51713] (1)
	tRNA-intron endonuclease N-terminal domain-like [ 55267] (1)
	tRNA-intron endonuclease catalytic domain-like [ 53032] (1)
	the cytoplasmic N-terminus of the bk beta-subunit kcnmb2 [ 70033] (1)

U

Superfamily	Description [Sunid] (#Children)
Prefixed with U	UDP-Glycosyltransferase/glycogen phosphorylase [ 53756] (11)
	Ubiquitin-like [ 54236] (8)
	UBA-like [ 46934] (4)
	UBC-like [ 54495] (4)
	Uracil-DNA glycosylase-like [ 52141] (4)
	UROD/MetE-like [ 51726] (2)
	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain [ 52413] (1)
	USP8 N-terminal domain-like [ 140856] (1)
	UbiD C-terminal domain-like [ 143968] (1)
	Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) [ 81508] (1)
	Ubiquitin [ 144345] (1)
	Ubiquitin interacting motif (UIM) [ 90303] (1)
	Undecaprenyl diphosphate synthase [ 64005] (1)
	Upper collar protein gp10 (connector protein) [ 56826] (1)
	UraD-Like [ 158694] (1)
	Uracil-DNA glycosylase inhibitor protein [ 54441] (1)
	Urease metallochaperone UreE, C-terminal domain [ 69737] (1)
	Urease metallochaperone UreE, N-terminal domain [ 69287] (1)
	Urease, beta-subunit [ 51278] (1)
	Urease, gamma-subunit [ 54111] (1)
	Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain [ 56194] (1)
	Urocanase [ 111326] (1)
	Uteroglobin-like [ 48201] (1)

V

Superfamily	Description [Sunid] (#Children)
Prefixed with V	vWA-like [ 53300] (5)
	Viral protein domain [ 49818] (3)
	Virus attachment protein globular domain [ 49835] (3)
	Viral glycoprotein ectodomain-like [ 161008] (2)
	V-region of surface antigen I/II (SA I/II, PAC) [ 74914] (1)
	V-type ATP synthase subunit C [ 103486] (1)
	V-type ATPase subunit E-like [ 160527] (1)
	VC0467-like [ 143456] (1)
	VHL [ 49468] (1)
	VHP, Villin headpiece domain [ 47050] (1)
	VMIP-II fragment [ 58764] (1)
	VP4 membrane interaction domain [ 111379] (1)
	VPA0735-like [ 160935] (1)
	VPR protein fragments [ 58354] (1)
	VPS28 C-terminal domain-like [ 140427] (1)
	VPS9 domain [ 109993] (1)
	VSV matrix protein [ 75404] (1)
	Vacuolar ATP synthase subunit C [ 118203] (1)
	Vacuolar targeting peptide from NA-PROPI (residues 29-54) [ 58560] (1)
	ValRS/IleRS/LeuRS editing domain [ 50677] (1)
	Vanabin-like [ 144129] (1)
	Variable surface antigen VlsE [ 74748] (1)
	Variant surface glycoprotein (N-terminal domain) [ 58087] (1)
	Variant surface glycoprotein MITAT 1.2, VSG 221, C-terminal domain [ 118251] (1)
	Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain [ 118370] (1)
	VhTI-like [ 161148] (1)
	Viral DNA-binding domain [ 54957] (1)
	Viral chemokine binding protein m3 [ 82046] (1)
	Viral glycoprotein, central and dimerisation domains [ 56983] (1)
	Viral leader polypeptide zinc finger [ 144251] (1)
	Viral ssDNA binding protein [ 118208] (1)
	Virulence-associated V antigen [ 103388] (1)
	Virus ectodomain [ 58069] (1)
	Virus envelope proteins [ 75719] (1)
	Viruses and virus-receptor complexes [ 58163] (1)
	Vitelline membrane outer protein-I (VMO-I) [ 51092] (1)
	Vng1086c-like [ 140371] (1)
	Voltage-gated potassium channels [ 81324] (1)

W

Superfamily	Description [Sunid] (#Children)
Prefixed with W	"Winged helix" DNA-binding domain [ 46785] (84)
	WD40 repeat-like [ 50978] (2)
	WGR domain-like [ 142921] (1)
	WRKY DNA-binding domain [ 118290] (1)
	WSSV envelope protein-like [ 158974] (1)
	WW domain [ 51045] (1)
	WW domain-based designs [ 58913] (1)
	WWE domain [ 117839] (1)
	Wiscott-Aldrich syndrome protein, WASP, C-terminal domain [ 47912] (1)

X

Superfamily	Description [Sunid] (#Children)
Prefixed with X	Xylose isomerase-like [ 51658] (7)
	XCC0632-like [ 159594] (2)
	X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain [ 81761] (1)
	XPC-binding domain [ 101238] (1)
	XRCC4, C-terminal oligomerization domain [ 58022] (1)
	XRCC4, N-terminal domain [ 50809] (1)
	XisI-like [ 143847] (1)
	XkdW-like [ 159865] (1)
	XseB-like [ 116842] (1)

Y

Superfamily	Description [Sunid] (#Children)
Prefixed with Y	YVTN repeat-like/Quinoprotein amine dehydrogenase [ 50969] (3)
	YcfA/nrd intein domain [ 54786] (3)
	YbeD/HP0495-like [ 117991] (2)
	Yeast killer toxins [ 55221] (2)
	YgaC/TfoX-N like [ 159894] (2)
	YheA/YmcA-like [ 158622] (2)
	YjgF-like [ 55298] (2)
	YktB/PF0168-like [ 142913] (2)
	YrdC/RibB [ 55821] (2)
	YAP1 redox domain [ 111430] (1)
	YNR034W-A-like [ 160683] (1)
	YWTD domain [ 63825] (1)
	YacF-like [ 160950] (1)
	YaeB-like [ 118196] (1)
	YajQ-like [ 89963] (1)
	YbaB-like [ 82607] (1)
	YbaK/ProRS associated domain [ 55826] (1)
	YbiA-like [ 143990] (1)
	YbjQ-like [ 117782] (1)
	YccV-like [ 141255] (1)
	YceI-like [ 101874] (1)
	YcfC-like [ 101322] (1)
	YcgL-like [ 160191] (1)
	YdfO-like [ 160419] (1)
	YdgH-like [ 159871] (1)
	YdhA-like [ 141488] (1)
	YdhG-like [ 159888] (1)
	YebC-like [ 75625] (1)
	YeeU-like [ 143737] (1)
	YefM-like [ 143120] (1)
	YegP-like [ 160113] (1)
	YehR-like [ 160704] (1)
	YehU-like [ 118001] (1)
	YejL-like [ 158651] (1)
	YerB-like [ 159774] (1)
	YfbU-like [ 116960] (1)
	YfgJ-like [ 161187] (1)
	YfmB-like [ 140688] (1)
	YgbK-like [ 142764] (1)
	YgfB-like [ 101327] (1)
	YgfY-like [ 109910] (1)
	YggU-like [ 69786] (1)
	YggX-like [ 111148] (1)
	YhbC-like, C-terminal domain [ 74942] (1)
	YhbC-like, N-terminal domain [ 75420] (1)
	YhbY-like [ 75471] (1)
	YidB-like [ 140804] (1)
	YjbQ-like [ 111038] (1)
	YjbR-like [ 142906] (1)
	YjeF N-terminal domain-like [ 64153] (1)
	YkuJ-like [ 143567] (1)
	YkvR-like [ 159173] (1)
	YlxR-like [ 64376] (1)
	YmcC-like [ 159270] (1)
	YnzC-like [ 158221] (1)
	YoaC-like [ 140670] (1)
	YojJ-like [ 143597] (1)
	YonK-like [ 160570] (1)
	YopH tyrosine phosphatase N-terminal domain [ 64449] (1)
	YopT-like [ 159222] (1)
	YopX-like [ 159006] (1)
	YorP-like [ 159038] (1)
	YozE-like [ 140652] (1)
	YppE-like [ 140415] (1)
	Ypt/Rab-GAP domain of gyp1p [ 47923] (1)
	YqaI-like [ 160713] (1)
	YqcC-like [ 158452] (1)
	YqgQ-like [ 158379] (1)
	YueI-like [ 160515] (1)
	YugE-like [ 116922] (1)
	YugN-like [ 160755] (1)
	YutG-like [ 101307] (1)
	YvfG-like [ 158388] (1)
	YwmB-like [ 143842] (1)

Z

Superfamily	Description [Sunid] (#Children)
Prefixed with Z	Zn-dependent exopeptidases [ 53187] (9)
	Zn-binding ribosomal proteins [ 57829] (8)
	Zinc beta-ribbon [ 57783] (5)
	Zinc domain conserved in yeast copper-regulated transcription factors [ 57879] (1)
	Zinc finger based beta-beta-alpha motif [ 58869] (1)
	Zinc finger design [ 58857] (1)
	Zinc finger domain of DNA polymerase-alpha [ 90234] (1)
	Zinc hairpin stack [ 161245] (1)
	Zinc-binding domain of translation initiation factor 2 beta [ 75689] (1)
	Zn-binding domains of ADDBP [ 57917] (1)
	Zn-finger domain of Sec23/24 [ 82919] (1)
	Zn2/Cys6 DNA-binding domain [ 57701] (1)

LINKOUT

SCOP hierarchy

Using a sunid (e.g., "81318") or a keyword (e.g., "RUNT domain"):

All superfamilies in alphabetic order (A to Z Index)

A

B

C

D

E

F

G

H

I

J

K

L

M

N

O

P

Q

R

S

T

U

V

W

X

Y

Z