PAZ domain superfamily

DO

Disease Ontology (DO)

	DO term	FDR (all)	SDDO (four levels)	Annotation (direct or inherited)
Disease Ontology (DO)	disease of cellular proliferation	0	--	Direct
Disease Ontology (DO)	cancer	0	--	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

MP

Mouse Phenotype (MP)

	MP term	FDR (all)	SDMP (four levels)	Annotation (direct or inherited)
Mammalian Phenotype (MP)	epidermal cyst	0.00000006908	--	Direct
Mammalian Phenotype (MP)	abnormal meiosis	0.0000001029	--	Direct
Mammalian Phenotype (MP)	hair follicle degeneration	0.0000004794	--	Direct
Mammalian Phenotype (MP)	decreased testis weight	0.0000007622	--	Direct
Mammalian Phenotype (MP)	decreased germ cell number	0.00001837	--	Direct
Mammalian Phenotype (MP)	abnormal hair follicle development	0.00002137	--	Direct
Mammalian Phenotype (MP)	abnormal testis size	0.00003568	--	Direct
Mammalian Phenotype (MP)	small gonad	0.00003918	--	Direct
Mammalian Phenotype (MP)	abnormal male germ cell morphology	0.00004099	--	Direct
Mammalian Phenotype (MP)	abnormal primary sex determination	0.00004636	--	Direct
Mammalian Phenotype (MP)	abnormal testis morphology	0.0001074	--	Direct
Mammalian Phenotype (MP)	abnormal gametogenesis	0.0002002	--	Direct
Mammalian Phenotype (MP)	abnormal male reproductive system morphology	0.0002966	--	Direct
Mammalian Phenotype (MP)	abnormal skin condition	0.0009041	--	Direct
Mammalian Phenotype (MP)	endocrine/exocrine gland phenotype	0.004226	--	Inherited
Mammalian Phenotype (MP)	reproductive system phenotype	0.01514	--	Inherited
Mammalian Phenotype (MP)	abnormal sex gland morphology	0.02287	--	Inherited
Mammalian Phenotype (MP)	abnormal skin morphology	0.03583	--	Inherited
Mammalian Phenotype (MP)	abnormal skin adnexa morphology	0.04371	--	Inherited
Mammalian Phenotype (MP)	abnormal male genitalia morphology	1	--	Inherited
Mammalian Phenotype (MP)	cellular phenotype	0.04221	Least Informative	Inherited
Mammalian Phenotype (MP)	abnormal reproductive system morphology	0.002424	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal gland morphology	0.002849	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal reproductive system physiology	0.006527	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal cell morphology	0.009254	Moderately Informative	Inherited
Mammalian Phenotype (MP)	integument phenotype	0.1689	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal sex determination	0.00006213	Informative	Direct
Mammalian Phenotype (MP)	abnormal spermatogenesis	0.0000737	Informative	Direct
Mammalian Phenotype (MP)	abnormal germ cell morphology	0.00007833	Informative	Direct
Mammalian Phenotype (MP)	abnormal male reproductive gland morphology	0.0002083	Informative	Direct
Mammalian Phenotype (MP)	abnormal internal male genitalia morphology	0.0002624	Informative	Direct
Mammalian Phenotype (MP)	abnormal epidermal layer morphology	0.002325	Informative	Inherited
Mammalian Phenotype (MP)	abnormal testis weight	0.000001087	Highly Informative	Direct
Mammalian Phenotype (MP)	decreased male germ cell number	0.000009801	Highly Informative	Direct
Mammalian Phenotype (MP)	small testis	0.00002566	Highly Informative	Direct
Mammalian Phenotype (MP)	thick epidermis	0.00005665	Highly Informative	Direct
Mammalian Phenotype (MP)	abnormal male reproductive system physiology	0.0005006	Highly Informative	Direct
Mammalian Phenotype (MP)	abnormal hair follicle morphology	0.0005935	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

WP

Worm Phenotype (WP)

	WP term	FDR (all)	SDWP (four levels)	Annotation (direct or inherited)
Worm Phenotype (WP)	lethal	0	--	Direct
Worm Phenotype (WP)	development variant	0	--	Direct
Worm Phenotype (WP)	organism development variant	0	--	Direct
Worm Phenotype (WP)	21U RNA expression variant	0.000000000001298	--	Direct
Worm Phenotype (WP)	siRNA expression variant	0.0000001801	--	Direct
Worm Phenotype (WP)	alae absent	0.0000009001	--	Direct
Worm Phenotype (WP)	somatic transgene silencing variant	0.00001052	--	Direct
Worm Phenotype (WP)	alae variant	0.00001453	--	Direct
Worm Phenotype (WP)	RNAi enhanced	0.00003431	--	Direct
Worm Phenotype (WP)	breaks in alae	0.00008008	--	Direct
Worm Phenotype (WP)	spermatogenesis variant	0.00008008	--	Direct
Worm Phenotype (WP)	cuticle morphology variant	0.002075	--	Inherited
Worm Phenotype (WP)	gene expression variant	0.005399	--	Inherited
Worm Phenotype (WP)	gametogenesis variant	0.02276	--	Inherited
Worm Phenotype (WP)	organism homeostasis metabolism variant	0.9837	--	Inherited
Worm Phenotype (WP)	organism physiology variant	0.9948	--	Inherited
Worm Phenotype (WP)	mRNA expression variant	1	--	Inherited
Worm Phenotype (WP)	physiology variant	1	--	Inherited
Worm Phenotype (WP)	morphology variant	1	--	Inherited
Worm Phenotype (WP)	organism metabolism processing variant	0.0253	Least Informative	Inherited
Worm Phenotype (WP)	cell development variant	0.3994	Least Informative	Inherited
Worm Phenotype (WP)	pericellular component development variant	0.03171	Moderately Informative	Inherited
Worm Phenotype (WP)	germ cell differentiation variant	0.8751	Moderately Informative	Inherited
Worm Phenotype (WP)	RNA expression variant	0.00000000000004508	Informative	Direct
Worm Phenotype (WP)	maintenance of gene silencing variant	0.0000000007787	Informative	Direct
Worm Phenotype (WP)	pericellular component morphology variant	0.003014	Informative	Inherited
Worm Phenotype (WP)	RNAi response variant	0.0000000002671	Highly Informative	Direct
Worm Phenotype (WP)	mRNA levels increased	0.00000521	Highly Informative	Direct
Worm Phenotype (WP)	cuticle development variant	0.0001617	Highly Informative	Direct
Worm Phenotype (WP)	alae morphology variant	0.0004407	Highly Informative	Direct
Worm Phenotype (WP)	transgene silencing variant	0.7424	Highly Informative	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

FP

Fly Phenotype (FP)

	FP term	FDR (all)	SDFP (four levels)	Annotation (direct or inherited)
Fly Phenotype (FP)	phenotype	0.5003	--	Inherited
Fly Phenotype (FP)	modifier of variegation	0.000009335	Informative	Direct
Fly Phenotype (FP)	cell cycle defective	0.00002606	Informative	Direct
Fly Phenotype (FP)	suppressor of variegation	0.000004456	Highly Informative	Direct
Fly Phenotype (FP)	mitotic cell cycle defective	0.000005466	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

FA

Fly Anatomy (FA)

	FA term	FDR (all)	SDFA (four levels)	Annotation (direct or inherited)
Fly Anatomy (FA)	organism	0	--	Direct
Fly Anatomy (FA)	multicellular structure	0	--	Direct
Fly Anatomy (FA)	stage 5 embryo	0.00002968	--	Direct
Fly Anatomy (FA)	pole cell	0.0001366	--	Direct
Fly Anatomy (FA)	blastoderm embryo	0.0002299	--	Direct
Fly Anatomy (FA)	gastrula embryo	0.004387	--	Inherited
Fly Anatomy (FA)	late embryo	0.4769	--	Inherited
Fly Anatomy (FA)	anatomical structure	1	--	Inherited
Fly Anatomy (FA)	material anatomical entity	1	--	Inherited
Fly Anatomy (FA)	cell	0.2961	Least Informative	Inherited
Fly Anatomy (FA)	embryo	0.05495	Moderately Informative	Inherited
Fly Anatomy (FA)	germline cell	0.001637	Informative	Inherited
Fly Anatomy (FA)	dorsal closure embryo	0.02146	Informative	Inherited
Fly Anatomy (FA)	extended germ band embryo	0.02785	Informative	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

ZA

Zebrafish Anatomy (ZA)

	ZA term	FDR (all)	SDZA (four levels)	Annotation (direct or inherited)
Zebrafish Anatomy (ZA)	whole organism	0	--	Direct
Zebrafish Anatomy (ZA)	anatomical structure	1	--	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

XA

Xenopus Anatomy (XA)

	XA term	FDR (all)	SDXA (four levels)	Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)	trunk region	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical structure	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical group	0	--	Direct
Xenopus ANatomical entity (XAN)	organism subdivision	0	--	Direct
Xenopus ANatomical entity (XAN)	compound organ	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical region	0	--	Direct
Xenopus ANatomical entity (XAN)	multicellular anatomical structure	0	--	Direct
Xenopus ANatomical entity (XAN)	whole organism	1	--	Inherited
Xenopus ANatomical entity (XAN)	trunk	0	Least Informative	Direct
Xenopus ANatomical entity (XAN)	cavitated compound organ	0	Least Informative	Direct

	XA term	FDR (all)	SDXA (four levels)	Annotation (direct or inherited)
Xenopus DEvelopment stage (XDE)	NF stage	0	--	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

AP

Arabidopsis Plant Ontology (AP)

	AP term	FDR (all)	SDAP (four levels)	Annotation (direct or inherited)
Plant structure DEvelopment stage (PDE)	whole plant development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	sporophyte vegetative stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	floral organ differentiation stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	corolla development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	flowering stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	plant embryo stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	collective plant organ structure development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	plant organ development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	reproductive shoot system development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	collective phyllome structure development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	floral organ formation stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	flower development stage	1	--	Inherited
Plant structure DEvelopment stage (PDE)	life of whole plant stage	1	--	Inherited
Plant structure DEvelopment stage (PDE)	shoot system development stage	1	--	Inherited
Plant structure DEvelopment stage (PDE)	sporophyte development stage	1	--	Inherited
Plant structure DEvelopment stage (PDE)	C globular stage	0	Least Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

EC

Enzyme Commission (EC)

	EC term	FDR (all)	SDEC (four levels)	Annotation (direct or inherited)
Enzyme Commission (EC)	Acting on ester bonds	0	--	Direct
Enzyme Commission (EC)	Argonaute-2	0	--	Direct
Enzyme Commission (EC)	Hydrolases	0	Least Informative	Direct
Enzyme Commission (EC)	Endoribonucleases producing 5'-phosphomonoesters	0	Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

CD

CTD Diseases (CD)

	CD term	FDR (all)	SDCD (four levels)	Annotation (direct or inherited)
CTD Diseases (CD)	Oligospermia	0.00000002004	--	Direct
CTD Diseases (CD)	Infertility	0.00005924	--	Direct
CTD Diseases (CD)	Genital Diseases, Male	0.02767	--	Inherited
CTD Diseases (CD)	Male Urogenital Diseases	0.1308	--	Inherited
CTD Diseases (CD)	Female Urogenital Diseases	0.1781	--	Inherited
CTD Diseases (CD)	Female Urogenital Diseases and Pregnancy Complications	0.2037	Least Informative	Inherited
CTD Diseases (CD)	Genital Diseases, Female	0.01673	Moderately Informative	Inherited
CTD Diseases (CD)	Infertility, Male	0.0000217	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

CC

CTD Chemicals (CC)

	CC term	FDR (all)	SDCC (four levels)	Annotation (direct or inherited)
CTD Chemicals (CC)	Heterocyclic Compounds, Fused-Ring	0	--	Direct
CTD Chemicals (CC)	Carboxylic Acids	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds, 1-Ring	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds, 2-Ring	0	--	Direct
CTD Chemicals (CC)	Organic Chemicals	0	--	Direct
CTD Chemicals (CC)	Polycyclic Compounds	0	--	Direct
CTD Chemicals (CC)	Pyrans	0	--	Direct
CTD Chemicals (CC)	Acids, Acyclic	0	Least Informative	Direct
CTD Chemicals (CC)	Benzopyrans	0	Least Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

Distribution on sTOL

Plot distribution on species Tree Of Life (sTOL) for this domain, i.e., present or absent across genomes/tips

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PAZ domain superfamily