dcGO - A comprehensive domain-centric ontology resource for post-genomic research on functions, phenotypes, diseases and more   
  
  

BRK domain-like superfamily

Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   GYF/BRK domain-like [ 55276] (2)
Superfamily:   BRK domain-like [ 160481]
Families:   BRK domain-like [ 160482] (2)

HP

Human Phenotype (HP)

HP term FDR (all) SDHP (four levels) Annotation (direct or inherited)
Mode of Inheritance (MI)Autosomal dominant inheritance0Least InformativeDirect
 
HP term FDR (all) SDHP (four levels) Annotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of body height0--Direct
Phenotypic Abnormality (PA)Abnormality of head or neck0--Direct
Phenotypic Abnormality (PA)Abnormality of skull size0--Direct
Phenotypic Abnormality (PA)Abnormality of the face0--Direct
Phenotypic Abnormality (PA)Abnormality of the orbital region0--Direct
Phenotypic Abnormality (PA)Abnormality of the nervous system0--Direct
Phenotypic Abnormality (PA)Abnormality of the skeletal system0--Direct
Phenotypic Abnormality (PA)Abnormality of the foot0--Direct
Phenotypic Abnormality (PA)Abnormal axial skeleton morphology0--Direct
Phenotypic Abnormality (PA)Abnormality of the ocular adnexa0--Direct
Phenotypic Abnormality (PA)Sparse hair0.000359--Direct
Phenotypic Abnormality (PA)Abnormality of hair density0.0004015--Direct
Phenotypic Abnormality (PA)Aplasia/hypoplasia involving bones of the lower limbs0.0004752--Direct
Phenotypic Abnormality (PA)Abnormality of skeletal maturation0.0006223--Direct
Phenotypic Abnormality (PA)Abnormality of mouth size0.0006305--Direct
Phenotypic Abnormality (PA)Aplasia/hypoplasia involving bones of the extremities0.003151--Inherited
Phenotypic Abnormality (PA)Abnormal hair morphology0.02001--Inherited
Phenotypic Abnormality (PA)Abnormality of the hand0.03367--Inherited
Phenotypic Abnormality (PA)Aplasia/hypoplasia involving the skeleton0.07811--Inherited
Phenotypic Abnormality (PA)Abnormal oral morphology0.09158--Inherited
Phenotypic Abnormality (PA)Abnormality of limb bone0.147--Inherited
Phenotypic Abnormality (PA)Abnormal appendicular skeleton morphology0.2192--Inherited
Phenotypic Abnormality (PA)Abnormality of the mouth0.4863--Inherited
Phenotypic Abnormality (PA)Abnormality of the head0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of nervous system physiology0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of limbs0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the integument0.1721Least InformativeInherited
Phenotypic Abnormality (PA)Abnormal skull morphology0Moderately InformativeDirect
Phenotypic Abnormality (PA)Growth abnormality0Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the lower limb0Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormality of higher mental function0Moderately InformativeDirect
Phenotypic Abnormality (PA)Neurodevelopmental abnormality0Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormal ocular adnexa morphology0Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormality of skin adnexa morphology0.02906Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of limb bone morphology0.04332Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skeletal physiology0.1541Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the upper limb0.4159Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal oral cavity morphology1Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the nose0InformativeDirect
Phenotypic Abnormality (PA)Abnormal eyelid morphology0InformativeDirect
Phenotypic Abnormality (PA)Intellectual disability0InformativeDirect
Phenotypic Abnormality (PA)Seizures0InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the palm0.0005405InformativeDirect
Phenotypic Abnormality (PA)Aplasia/hypoplasia of the extremities0.04414InformativeInherited
Phenotypic Abnormality (PA)Abnormal lower limb bone morphology0.06211InformativeInherited
Phenotypic Abnormality (PA)Delayed skeletal maturation0.00044Highly InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

ZA

Zebrafish Anatomy (ZA)

ZA term FDR (all) SDZA (four levels) Annotation (direct or inherited)
Zebrafish Anatomy (ZA)brain0--Direct
Zebrafish Anatomy (ZA)whole organism0--Direct
Zebrafish Anatomy (ZA)visual system0--Direct
Zebrafish Anatomy (ZA)anatomical system0--Direct
Zebrafish Anatomy (ZA)cavitated compound organ0--Direct
Zebrafish Anatomy (ZA)anatomical group0--Direct
Zebrafish Anatomy (ZA)electrically active cell0--Direct
Zebrafish Anatomy (ZA)anatomical structure1--Inherited
Zebrafish Anatomy (ZA)nervous system0Least InformativeDirect
Zebrafish Anatomy (ZA)compound organ0Least InformativeDirect
Zebrafish Anatomy (ZA)organism subdivision0Least InformativeDirect
Zebrafish Anatomy (ZA)multi-tissue structure0Least InformativeDirect
Zebrafish Anatomy (ZA)cell0Least InformativeDirect
Zebrafish Anatomy (ZA)central nervous system0Moderately InformativeDirect
Zebrafish Anatomy (ZA)sensory system0Moderately InformativeDirect
Zebrafish Anatomy (ZA)head0Moderately InformativeDirect
Zebrafish Anatomy (ZA)eye0InformativeDirect
Zebrafish Anatomy (ZA)digestive system0InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

XA

Xenopus Anatomy (XA)

XA term FDR (all) SDXA (four levels) Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)head region0--Direct
Xenopus ANatomical entity (XAN)trunk region0--Direct
Xenopus ANatomical entity (XAN)genital system0--Direct
Xenopus ANatomical entity (XAN)male genitalia0--Direct
Xenopus ANatomical entity (XAN)central nervous system0--Direct
Xenopus ANatomical entity (XAN)anatomical structure0--Direct
Xenopus ANatomical entity (XAN)anatomical group0--Direct
Xenopus ANatomical entity (XAN)male organism0--Direct
Xenopus ANatomical entity (XAN)organism subdivision0--Direct
Xenopus ANatomical entity (XAN)compound organ0--Direct
Xenopus ANatomical entity (XAN)gonad0--Direct
Xenopus ANatomical entity (XAN)anatomical region0--Direct
Xenopus ANatomical entity (XAN)multicellular anatomical structure0--Direct
Xenopus ANatomical entity (XAN)otic vesicle0.000579--Direct
Xenopus ANatomical entity (XAN)anatomical system1--Inherited
Xenopus ANatomical entity (XAN)whole organism1--Inherited
Xenopus ANatomical entity (XAN)urogenital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)nervous system0Least InformativeDirect
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)trunk0Least InformativeDirect
Xenopus ANatomical entity (XAN)tissue0Least InformativeDirect
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect
Xenopus ANatomical entity (XAN)brain0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)testis0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)sensory system0.005864Moderately InformativeInherited
Xenopus ANatomical entity (XAN)multi-tissue structure0.007496Moderately InformativeInherited
Xenopus ANatomical entity (XAN)vestibuloauditory system0.0001327InformativeDirect
Xenopus ANatomical entity (XAN)forebrain0.0005119InformativeDirect
Xenopus ANatomical entity (XAN)midbrain0.0003158Highly InformativeDirect
Xenopus ANatomical entity (XAN)hindbrain0.0004706Highly InformativeDirect
 
XA term FDR (all) SDXA (four levels) Annotation (direct or inherited)
Xenopus DEvelopment stage (XDE)NF stage0--Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

EC

Enzyme Commission (EC)

EC term FDR (all) SDEC (four levels) Annotation (direct or inherited)
Enzyme Commission (EC)Acting on ATP; involved in cellular and subcellular movement0--Direct
Enzyme Commission (EC)Hydrolases0Least InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides0Moderately InformativeDirect
Enzyme Commission (EC)DNA helicase0InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

CD

CTD Diseases (CD)

CD term FDR (all) SDCD (four levels) Annotation (direct or inherited)
CTD Diseases (CD)Signs and Symptoms0.0422--Inherited
CTD Diseases (CD)Nervous System Diseases0.1313Least InformativeInherited
CTD Diseases (CD)Pathological Conditions, Signs and Symptoms0.2825Least InformativeInherited
CTD Diseases (CD)Neurologic Manifestations0.01994Moderately InformativeInherited
CTD Diseases (CD)Mental Disorders0.02949Moderately InformativeInherited
CTD Diseases (CD)Neurobehavioral Manifestations0.002027InformativeInherited
CTD Diseases (CD)Neurodevelopmental Disorders0.006438InformativeInherited
CTD Diseases (CD)Intellectual Disability0.0009874Highly InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

CC

CTD Chemicals (CC)

CC term FDR (all) SDCC (four levels) Annotation (direct or inherited)
CTD Chemicals (CC)Heterocyclic Compounds, 1-Ring0--Direct
CTD Chemicals (CC)Carboxylic Acids0--Direct
CTD Chemicals (CC)Polycyclic Compounds0--Direct
CTD Chemicals (CC)Heterocyclic Compounds, 2-Ring0--Direct
CTD Chemicals (CC)Hydrocarbons, Cyclic0--Direct
CTD Chemicals (CC)Glycosides0--Direct
CTD Chemicals (CC)Pyrenes0--Direct
CTD Chemicals (CC)Heterocyclic Compounds, Fused-Ring0--Direct
CTD Chemicals (CC)Heterocyclic Compounds0--Direct
CTD Chemicals (CC)Organic Chemicals0--Direct
CTD Chemicals (CC)Hydrocarbons0--Direct
CTD Chemicals (CC)Hydrocarbons, Aromatic0--Direct
CTD Chemicals (CC)Inorganic Chemicals0--Direct
CTD Chemicals (CC)epigallocatechin gallate0.0009877--Direct
CTD Chemicals (CC)Chromones0.03666--Inherited
CTD Chemicals (CC)Pyrans0.4936--Inherited
CTD Chemicals (CC)Pyrimidines0Least InformativeDirect
CTD Chemicals (CC)Sulfur Compounds0Least InformativeDirect
CTD Chemicals (CC)Electrolytes0Least InformativeDirect
CTD Chemicals (CC)Carbohydrates0Least InformativeDirect
CTD Chemicals (CC)Amines0Least InformativeDirect
CTD Chemicals (CC)Polycyclic Aromatic Hydrocarbons0Least InformativeDirect
CTD Chemicals (CC)Benzopyrans0.5456Least InformativeInherited
CTD Chemicals (CC)Benzopyrenes0Moderately InformativeDirect
CTD Chemicals (CC)Flavonoids0.03615Moderately InformativeInherited
CTD Chemicals (CC)Chromans0.007579InformativeInherited
CTD Chemicals (CC)Catechin0.02202Highly InformativeInherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

Distribution on sTOL

Plot distribution on species Tree Of Life (sTOL) for this domain, i.e., present or absent across genomes/tips
Plot tree as:   Download Newick format tree:   Browsing in TREE OF LIFE:
(show help)