Saposin superfamily

DO

Disease Ontology (DO)

	DO term	FDR (all)	SDDO (four levels)	Annotation (direct or inherited)
Disease Ontology (DO)	disease of cellular proliferation	0	--	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

HP

Human Phenotype (HP)

	HP term	FDR (all)	SDHP (four levels)	Annotation (direct or inherited)
Mode of Inheritance (MI)	Autosomal recessive inheritance	0	--	Direct

	HP term	FDR (all)	SDHP (four levels)	Annotation (direct or inherited)
Phenotypic Abnormality (PA)	Abnormality of the skeletal system	0	--	Direct
Phenotypic Abnormality (PA)	Abnormal respiratory system morphology	0	--	Direct
Phenotypic Abnormality (PA)	Abnormality of the cardiovascular system	0	Least Informative	Direct
Phenotypic Abnormality (PA)	Abnormality of metabolism/homeostasis	0	Least Informative	Direct
Phenotypic Abnormality (PA)	Abnormality of skeletal morphology	0	Least Informative	Direct
Phenotypic Abnormality (PA)	Abnormality of the respiratory system	0	Moderately Informative	Direct
Phenotypic Abnormality (PA)	Abnormality of the vasculature	0	Moderately Informative	Direct
Phenotypic Abnormality (PA)	Abnormal lung morphology	0	Informative	Direct
Phenotypic Abnormality (PA)	Functional respiratory abnormality	0	Informative	Direct
Phenotypic Abnormality (PA)	Respiratory insufficiency	0	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

WP

Worm Phenotype (WP)

	WP term	FDR (all)	SDWP (four levels)	Annotation (direct or inherited)
Worm Phenotype (WP)	lethal	0	--	Direct
Worm Phenotype (WP)	development variant	0	--	Direct
Worm Phenotype (WP)	organism development variant	0	--	Direct
Worm Phenotype (WP)	increased pathogen survival	0.00000000000003527	--	Direct
Worm Phenotype (WP)	pathogen load variant	0.00000000127	--	Direct
Worm Phenotype (WP)	radiation induced germ cell apoptosis variant	0.000001751	--	Direct
Worm Phenotype (WP)	germ cell resistant ionizing radiation	0.00001294	--	Direct
Worm Phenotype (WP)	cell ionizing radiation response variant	0.002544	--	Inherited
Worm Phenotype (WP)	transgene expression variant	0.005558	--	Inherited
Worm Phenotype (WP)	gene expression variant	0.02037	--	Inherited
Worm Phenotype (WP)	germ cell physiology variant	0.1426	--	Inherited
Worm Phenotype (WP)	programmed cell death variant	0.2016	--	Inherited
Worm Phenotype (WP)	cell death variant	0.2239	--	Inherited
Worm Phenotype (WP)	reproductive system physiology variant	0.7837	--	Inherited
Worm Phenotype (WP)	organ system physiology variant	0.7867	--	Inherited
Worm Phenotype (WP)	behavior variant	0.8202	--	Inherited
Worm Phenotype (WP)	organism homeostasis metabolism variant	0.9479	--	Inherited
Worm Phenotype (WP)	organism physiology variant	0.9619	--	Inherited
Worm Phenotype (WP)	physiology variant	1	--	Inherited
Worm Phenotype (WP)	organism metabolism processing variant	0.06781	Least Informative	Inherited
Worm Phenotype (WP)	organism environmental stimulus response variant	0.1095	Least Informative	Inherited
Worm Phenotype (WP)	organism behavior variant	0.8138	Least Informative	Inherited
Worm Phenotype (WP)	cell physiology variant	1	Least Informative	Inherited
Worm Phenotype (WP)	level of transgene expression variant	0.000006782	Moderately Informative	Direct
Worm Phenotype (WP)	organism stress response variant	0.004527	Moderately Informative	Inherited
Worm Phenotype (WP)	apoptosis variant	0.1746	Moderately Informative	Inherited
Worm Phenotype (WP)	cell homeostasis metabolism variant	0.464	Moderately Informative	Inherited
Worm Phenotype (WP)	transgene expression reduced	0.0009418	Informative	Direct
Worm Phenotype (WP)	egg laying variant	0.02933	Informative	Inherited
Worm Phenotype (WP)	organism ionizing radiation response variant	0.08195	Informative	Inherited
Worm Phenotype (WP)	cell stress response variant	0.09039	Informative	Inherited
Worm Phenotype (WP)	organism pathogen response variant	0.1801	Informative	Inherited
Worm Phenotype (WP)	fewer eggs laid	0.000000001501	Highly Informative	Direct
Worm Phenotype (WP)	mutagen induced apoptosis variant	0.00001294	Highly Informative	Direct
Worm Phenotype (WP)	germ cell ionizing radiation response variant	0.0008987	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

AP

Arabidopsis Plant Ontology (AP)

	AP term	FDR (all)	SDAP (four levels)	Annotation (direct or inherited)
Plant ANatomical entity (PAN)	stomatal complex	0	--	Direct
Plant ANatomical entity (PAN)	epidermal cell	0	--	Direct
Plant ANatomical entity (PAN)	shoot internode	0	--	Direct
Plant ANatomical entity (PAN)	epidermis	0	--	Direct
Plant ANatomical entity (PAN)	phyllome	0	--	Direct
Plant ANatomical entity (PAN)	shoot epidermis	0	--	Direct
Plant ANatomical entity (PAN)	plant cell	0	--	Direct
Plant ANatomical entity (PAN)	shoot system	0	--	Direct
Plant ANatomical entity (PAN)	portion of plant tissue	0	--	Direct
Plant ANatomical entity (PAN)	plant organ	0	--	Direct
Plant ANatomical entity (PAN)	vascular leaf	0	--	Direct
Plant ANatomical entity (PAN)	stem	0	--	Direct
Plant ANatomical entity (PAN)	leaf apex	0	--	Direct
Plant ANatomical entity (PAN)	stem internode	0	--	Direct
Plant ANatomical entity (PAN)	cardinal organ part	0	--	Direct
Plant ANatomical entity (PAN)	plant axis	0	--	Direct
Plant ANatomical entity (PAN)	collective leaf structure	0	--	Direct
Plant ANatomical entity (PAN)	reproductive shoot system	0	--	Direct
Plant ANatomical entity (PAN)	phyllome apex	0	--	Direct
Plant ANatomical entity (PAN)	shoot epidermal cell	0	--	Direct
Plant ANatomical entity (PAN)	multi-tissue plant structure	0	--	Direct
Plant ANatomical entity (PAN)	collective plant structure	0	--	Direct
Plant ANatomical entity (PAN)	plant structure	1	--	Inherited
Plant ANatomical entity (PAN)	collective plant organ structure	1	--	Inherited
Plant ANatomical entity (PAN)	guard cell	0	Least Informative	Direct
Plant ANatomical entity (PAN)	flower	0	Least Informative	Direct
Plant ANatomical entity (PAN)	collective phyllome structure	0	Least Informative	Direct
Plant ANatomical entity (PAN)	shoot axis	0	Least Informative	Direct
Plant ANatomical entity (PAN)	leaf	0	Least Informative	Direct
Plant ANatomical entity (PAN)	cardinal part of multi-tissue plant structure	0	Least Informative	Direct

	AP term	FDR (all)	SDAP (four levels)	Annotation (direct or inherited)
Plant structure DEvelopment stage (PDE)	whole plant development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	1 main shoot growth stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	leaf production stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	sporophyte vegetative stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	floral organ differentiation stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	corolla development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	collective plant organ structure development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	plant organ development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	reproductive shoot system development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	collective phyllome structure development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	floral organ formation stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	flower development stage	1	--	Inherited
Plant structure DEvelopment stage (PDE)	life of whole plant stage	1	--	Inherited
Plant structure DEvelopment stage (PDE)	shoot system development stage	1	--	Inherited
Plant structure DEvelopment stage (PDE)	sporophyte development stage	1	--	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

EC

Enzyme Commission (EC)

	EC term	FDR (all)	SDEC (four levels)	Annotation (direct or inherited)
Enzyme Commission (EC)	Sphingomyelin phosphodiesterase	0	--	Direct
Enzyme Commission (EC)	Acyloxyacyl hydrolase	2.574e-16	--	Direct
Enzyme Commission (EC)	Acting on ester bonds	0.000008629	--	Direct
Enzyme Commission (EC)	Hydrolases	0	Least Informative	Direct
Enzyme Commission (EC)	Phosphoric diester hydrolases	0.000000009605	Informative	Direct
Enzyme Commission (EC)	Carboxylic ester hydrolases	0.2506	Informative	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

CC

CTD Chemicals (CC)

	CC term	FDR (all)	SDCC (four levels)	Annotation (direct or inherited)
CTD Chemicals (CC)	Benzene Derivatives	0	--	Direct
CTD Chemicals (CC)	Carboxylic Acids	0	--	Direct
CTD Chemicals (CC)	Hydrocarbons	0	--	Direct
CTD Chemicals (CC)	Hydrocarbons, Aromatic	0	--	Direct
CTD Chemicals (CC)	Hydrocarbons, Cyclic	0	--	Direct
CTD Chemicals (CC)	Organic Chemicals	0	--	Direct
CTD Chemicals (CC)	Acids, Acyclic	0	Least Informative	Direct