Formate/glycerate dehydrogenase catalytic domain-like superfamily

HP

Human Phenotype (HP)

	HP term	FDR (all)	SDHP (four levels)	Annotation (direct or inherited)
Phenotypic Abnormality (PA)	Abnormal circulating carboxylic acid concentration	0.004946	--	Inherited
Phenotypic Abnormality (PA)	Abnormality of metabolism/homeostasis	0.06015	Least Informative	Inherited
Phenotypic Abnormality (PA)	Abnormal circulating metabolite concentration	0.09726	Moderately Informative	Inherited
Phenotypic Abnormality (PA)	Abnormality of serum amino acid level	0.000196	Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

MP

Mouse Phenotype (MP)

	MP term	FDR (all)	SDMP (four levels)	Annotation (direct or inherited)
Mammalian Phenotype (MP)	abnormal embryonic neuroepithelium morphology	0.00002669	--	Direct
Mammalian Phenotype (MP)	abnormal embryonic tissue morphology	0.01538	--	Inherited
Mammalian Phenotype (MP)	abnormal embryo morphology	0.03511	--	Inherited
Mammalian Phenotype (MP)	abnormal nervous system morphology	0.184	--	Inherited
Mammalian Phenotype (MP)	nervous system phenotype	0.2766	Least Informative	Inherited
Mammalian Phenotype (MP)	abnormal nervous system development	0.02806	Moderately Informative	Inherited
Mammalian Phenotype (MP)	embryo phenotype	0.06633	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal neural tube morphology	0.003521	Informative	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

WP

Worm Phenotype (WP)

	WP term	FDR (all)	SDWP (four levels)	Annotation (direct or inherited)
Worm Phenotype (WP)	growth variant	0	--	Direct
Worm Phenotype (WP)	postembryonic development variant	0	--	Direct
Worm Phenotype (WP)	embryonic lethal	0	--	Direct
Worm Phenotype (WP)	larval arrest	0	--	Direct
Worm Phenotype (WP)	lethal	0	--	Direct
Worm Phenotype (WP)	fertility variant	0	--	Direct
Worm Phenotype (WP)	development variant	0	--	Direct
Worm Phenotype (WP)	morphology variant	0	--	Direct
Worm Phenotype (WP)	organism development variant	0	--	Direct
Worm Phenotype (WP)	organism morphology variant	0	--	Direct
Worm Phenotype (WP)	organ system physiology variant	0	--	Direct
Worm Phenotype (WP)	organism physiology variant	0	--	Direct
Worm Phenotype (WP)	organism homeostasis metabolism variant	0	--	Direct
Worm Phenotype (WP)	reproductive system physiology variant	0	--	Direct
Worm Phenotype (WP)	maternal sterile	0	--	Direct
Worm Phenotype (WP)	hermaphrodite sterile	0	--	Direct
Worm Phenotype (WP)	embryonic development variant	0	--	Direct
Worm Phenotype (WP)	hermaphrodite fertility variant	0	--	Direct
Worm Phenotype (WP)	developmental growth variant	0	--	Direct
Worm Phenotype (WP)	hermaphrodite fertility reduced	0	--	Direct
Worm Phenotype (WP)	fertility reduced	0	--	Direct
Worm Phenotype (WP)	physiology variant	1	--	Inherited
Worm Phenotype (WP)	sterile	1	--	Inherited
Worm Phenotype (WP)	larval lethal	0	Least Informative	Direct
Worm Phenotype (WP)	larval development variant	0	Least Informative	Direct
Worm Phenotype (WP)	larval growth variant	0	Least Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

YP

Yeast Phenotype (YP)

	YP term	FDR (all)	SDYP (four levels)	Annotation (direct or inherited)
Yeast Phenotype (YP)	competitive fitness	0	--	Direct
Yeast Phenotype (YP)	fitness	0	--	Direct
Yeast Phenotype (YP)	metabolism and growth	0	Least Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

ZA

Zebrafish Anatomy (ZA)

	ZA term	FDR (all)	SDZA (four levels)	Annotation (direct or inherited)
Zebrafish Anatomy (ZA)	whole organism	0	--	Direct
Zebrafish Anatomy (ZA)	anatomical structure	1	--	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

XA

Xenopus Anatomy (XA)

	XA term	FDR (all)	SDXA (four levels)	Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)	trunk region	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical structure	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical group	0	--	Direct
Xenopus ANatomical entity (XAN)	organism subdivision	0	--	Direct
Xenopus ANatomical entity (XAN)	compound organ	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical region	0	--	Direct
Xenopus ANatomical entity (XAN)	multicellular anatomical structure	0	--	Direct
Xenopus ANatomical entity (XAN)	whole organism	1	--	Inherited
Xenopus ANatomical entity (XAN)	trunk	0	Least Informative	Direct
Xenopus ANatomical entity (XAN)	cavitated compound organ	0	Least Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

AP

Arabidopsis Plant Ontology (AP)

	AP term	FDR (all)	SDAP (four levels)	Annotation (direct or inherited)
Plant ANatomical entity (PAN)	stomatal complex	0	--	Direct
Plant ANatomical entity (PAN)	epidermal cell	0	--	Direct
Plant ANatomical entity (PAN)	epidermis	0	--	Direct
Plant ANatomical entity (PAN)	shoot epidermis	0	--	Direct
Plant ANatomical entity (PAN)	plant cell	0	--	Direct
Plant ANatomical entity (PAN)	shoot system	0	--	Direct
Plant ANatomical entity (PAN)	portion of plant tissue	0	--	Direct
Plant ANatomical entity (PAN)	plant organ	0	--	Direct
Plant ANatomical entity (PAN)	stem	0	--	Direct
Plant ANatomical entity (PAN)	plant axis	0	--	Direct
Plant ANatomical entity (PAN)	shoot epidermal cell	0	--	Direct
Plant ANatomical entity (PAN)	multi-tissue plant structure	0	--	Direct
Plant ANatomical entity (PAN)	collective plant structure	0	--	Direct
Plant ANatomical entity (PAN)	vascular system	0.004792	--	Inherited
Plant ANatomical entity (PAN)	plant structure	1	--	Inherited
Plant ANatomical entity (PAN)	collective plant organ structure	1	--	Inherited
Plant ANatomical entity (PAN)	guard cell	0	Least Informative	Direct
Plant ANatomical entity (PAN)	shoot axis	0	Least Informative	Direct
Plant ANatomical entity (PAN)	whole plant	0.08546	Least Informative	Inherited
Plant ANatomical entity (PAN)	portion of vascular tissue	0.0008212	Informative	Direct
Plant ANatomical entity (PAN)	vascular bundle	0.000004694	Highly Informative	Direct

	AP term	FDR (all)	SDAP (four levels)	Annotation (direct or inherited)
Plant structure DEvelopment stage (PDE)	whole plant development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	1 main shoot growth stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	leaf production stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	sporophyte vegetative stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	floral organ differentiation stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	corolla development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	flowering stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	plant embryo stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	collective plant organ structure development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	plant organ development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	reproductive shoot system development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	collective phyllome structure development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	phyllome development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	floral organ formation stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	leaf development stage	1	--	Inherited
Plant structure DEvelopment stage (PDE)	flower development stage	1	--	Inherited
Plant structure DEvelopment stage (PDE)	life of whole plant stage	1	--	Inherited
Plant structure DEvelopment stage (PDE)	shoot system development stage	1	--	Inherited
Plant structure DEvelopment stage (PDE)	sporophyte development stage	1	--	Inherited
Plant structure DEvelopment stage (PDE)	4 leaf senescence stage	0	Least Informative	Direct
Plant structure DEvelopment stage (PDE)	C globular stage	0	Least Informative	Direct
Plant structure DEvelopment stage (PDE)	LP.12 twelve leaves visible stage	0	Least Informative	Direct
Plant structure DEvelopment stage (PDE)	LP.10 ten leaves visible stage	0	Least Informative	Direct
Plant structure DEvelopment stage (PDE)	LP.04 four leaves visible stage	0	Least Informative	Direct
Plant structure DEvelopment stage (PDE)	LP.06 six leaves visible stage	0	Least Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

EC

Enzyme Commission (EC)

	EC term	FDR (all)	SDEC (four levels)	Annotation (direct or inherited)
Enzyme Commission (EC)	D-lactate dehydrogenase	0	--	Direct
Enzyme Commission (EC)	4-phosphoerythronate dehydrogenase	0	--	Direct
Enzyme Commission (EC)	2-oxoglutarate reductase	0	--	Direct
Enzyme Commission (EC)	Glyoxylate reductase (NADP(+))	0	--	Direct
Enzyme Commission (EC)	Hydroxypyruvate reductase	0	--	Direct
Enzyme Commission (EC)	Phosphoglycerate dehydrogenase	0	--	Direct
Enzyme Commission (EC)	Formate dehydrogenase	0	--	Direct
Enzyme Commission (EC)	Alanine dehydrogenase	0	--	Direct
Enzyme Commission (EC)	Thioether and trialkylsulfonium hydrolases	0	--	Direct
Enzyme Commission (EC)	Proton-translocating NAD(P)(+) transhydrogenase	0	--	Direct
Enzyme Commission (EC)	Saccharopine dehydrogenase (NAD(+), L-lysine-forming)	0.00000000000000252	--	Direct
Enzyme Commission (EC)	Glyoxylate reductase	0.00000000000005473	--	Direct
Enzyme Commission (EC)	Saccharopine dehydrogenase (NADP(+), L-lysine-forming)	0.0000000002014	--	Direct
Enzyme Commission (EC)	Saccharopine dehydrogenase (NAD(+), L-glutamate-forming)	0.0000000002014	--	Direct
Enzyme Commission (EC)	Hydron translocation or charge separation linked to oxidoreductase reactions	0.000000003518	--	Direct
Enzyme Commission (EC)	With NAD(+) or NADP(+) as acceptor	0.00000001318	--	Direct
Enzyme Commission (EC)	Glycerate dehydrogenase	0.00000008459	--	Direct
Enzyme Commission (EC)	N(5)-(carboxyethyl)ornithine synthase	0.0000002269	--	Direct
Enzyme Commission (EC)	Gluconate 2-dehydrogenase	0.0000009013	--	Direct
Enzyme Commission (EC)	Translocases	0.8401	--	Inherited
Enzyme Commission (EC)	Oxidoreductases	0	Least Informative	Direct
Enzyme Commission (EC)	Hydrolases	0	Least Informative	Direct
Enzyme Commission (EC)	Acting on the CH-OH group of donors	0	Moderately Informative	Direct
Enzyme Commission (EC)	With NAD(+) or NADP(+) as acceptor	0	Informative	Direct
Enzyme Commission (EC)	Acting on the CH-NH(2) group of donors	0.01026	Informative	Inherited
Enzyme Commission (EC)	Catalysing the translocation of hydrons	0.07234	Informative	Inherited
Enzyme Commission (EC)	Acting on the CH-NH group of donors	0.2363	Informative	Inherited
Enzyme Commission (EC)	Acting on CH or CH(2) groups	0.4411	Informative	Inherited
Enzyme Commission (EC)	With NAD(+) or NADP(+) as acceptor	0	Highly Informative	Direct
Enzyme Commission (EC)	Acting on ether bonds	0	Highly Informative	Direct
Enzyme Commission (EC)	With NAD(+) or NADP(+) as acceptor	0.0000000009247	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

CC

CTD Chemicals (CC)

	CC term	FDR (all)	SDCC (four levels)	Annotation (direct or inherited)
CTD Chemicals (CC)	Heterocyclic Compounds, Fused-Ring	0	--	Direct
CTD Chemicals (CC)	Benzene Derivatives	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds, 1-Ring	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds, 2-Ring	0	--	Direct
CTD Chemicals (CC)	Hydrocarbons	0	--	Direct
CTD Chemicals (CC)	Hydrocarbons, Aromatic	0	--	Direct
CTD Chemicals (CC)	Hydrocarbons, Cyclic	0	--	Direct
CTD Chemicals (CC)	Inorganic Chemicals	0	--	Direct
CTD Chemicals (CC)	Organic Chemicals	0	--	Direct
CTD Chemicals (CC)	Polycyclic Compounds	0	--	Direct
CTD Chemicals (CC)	Electrolytes	0	Least Informative	Direct
CTD Chemicals (CC)	Polycyclic Aromatic Hydrocarbons	0	Least Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

Distribution on sTOL

Plot distribution on species Tree Of Life (sTOL) for this domain, i.e., present or absent across genomes/tips

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Formate/glycerate dehydrogenase catalytic domain-like superfamily