Arginase/deacetylase superfamily

DO

Disease Ontology (DO)

	DO term	FDR (all)	SDDO (four levels)	Annotation (direct or inherited)
Disease Ontology (DO)	cancer	0.01813	--	Inherited
Disease Ontology (DO)	disease of cellular proliferation	0.02123	--	Inherited
Disease Ontology (DO)	immune system cancer	0.7543	--	Inherited
Disease Ontology (DO)	organ system cancer	0.4675	Least Informative	Inherited
Disease Ontology (DO)	hematologic cancer	0.4181	Moderately Informative	Inherited
Disease Ontology (DO)	lymphoma	0.002098	Informative	Inherited
Disease Ontology (DO)	Hodgkin's lymphoma	0.0001664	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

HP

Human Phenotype (HP)

	HP term	FDR (all)	SDHP (four levels)	Annotation (direct or inherited)
Phenotypic Abnormality (PA)	Abnormality of the nervous system	0	--	Direct
Phenotypic Abnormality (PA)	Growth delay	0	--	Direct
Phenotypic Abnormality (PA)	Short foot	0.00001897	--	Direct
Phenotypic Abnormality (PA)	Aplasia/Hypoplasia involving bones of the feet	0.0002149	--	Direct
Phenotypic Abnormality (PA)	Aplasia/hypoplasia involving bones of the lower limbs	0.0004752	--	Direct
Phenotypic Abnormality (PA)	Aplasia/hypoplasia involving bones of the extremities	0.003151	--	Inherited
Phenotypic Abnormality (PA)	Aplasia/hypoplasia involving the skeleton	0.01762	--	Inherited
Phenotypic Abnormality (PA)	Abnormality of the foot	0.0285	--	Inherited
Phenotypic Abnormality (PA)	Abnormality of the hand	0.03367	--	Inherited
Phenotypic Abnormality (PA)	Abnormality of limb bone	0.04332	--	Inherited
Phenotypic Abnormality (PA)	Abnormal appendicular skeleton morphology	0.05293	--	Inherited
Phenotypic Abnormality (PA)	Abnormality of the skeletal system	0.277	--	Inherited
Phenotypic Abnormality (PA)	Abnormality of nervous system physiology	0	Least Informative	Direct
Phenotypic Abnormality (PA)	Abnormality of limbs	0.1053	Least Informative	Inherited
Phenotypic Abnormality (PA)	Abnormality of skeletal morphology	0.2525	Least Informative	Inherited
Phenotypic Abnormality (PA)	Growth abnormality	0	Moderately Informative	Direct
Phenotypic Abnormality (PA)	Abnormality of higher mental function	0	Moderately Informative	Direct
Phenotypic Abnormality (PA)	Neurodevelopmental abnormality	0	Moderately Informative	Direct
Phenotypic Abnormality (PA)	Abnormality of the upper limb	0.04175	Moderately Informative	Inherited
Phenotypic Abnormality (PA)	Abnormality of limb bone morphology	0.04332	Moderately Informative	Inherited
Phenotypic Abnormality (PA)	Abnormality of the lower limb	0.04577	Moderately Informative	Inherited
Phenotypic Abnormality (PA)	Intellectual disability	0	Informative	Direct
Phenotypic Abnormality (PA)	Abnormality of the palm	0.0005405	Informative	Direct
Phenotypic Abnormality (PA)	Abnormal lower limb bone morphology	0.003761	Informative	Inherited
Phenotypic Abnormality (PA)	Aplasia/hypoplasia of the extremities	0.003814	Informative	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

MP

Mouse Phenotype (MP)

	MP term	FDR (all)	SDMP (four levels)	Annotation (direct or inherited)
Mammalian Phenotype (MP)	increased fibroblast apoptosis	0.00001073	--	Direct
Mammalian Phenotype (MP)	abnormal fibroblast apoptosis	0.00004771	--	Direct
Mammalian Phenotype (MP)	increased cell death	0.08553	--	Inherited
Mammalian Phenotype (MP)	abnormal apoptosis	0.2103	--	Inherited
Mammalian Phenotype (MP)	abnormal cell physiology	0.6868	--	Inherited
Mammalian Phenotype (MP)	cellular phenotype	0.4905	Least Informative	Inherited
Mammalian Phenotype (MP)	abnormal cell death	0.2575	Moderately Informative	Inherited
Mammalian Phenotype (MP)	increased apoptosis	0.0845	Informative	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

WP

Worm Phenotype (WP)

	WP term	FDR (all)	SDWP (four levels)	Annotation (direct or inherited)
Worm Phenotype (WP)	growth variant	0	--	Direct
Worm Phenotype (WP)	postembryonic development variant	0	--	Direct
Worm Phenotype (WP)	embryonic lethal	0	--	Direct
Worm Phenotype (WP)	larval arrest	0	--	Direct
Worm Phenotype (WP)	lethal	0	--	Direct
Worm Phenotype (WP)	progeny variant	0	--	Direct
Worm Phenotype (WP)	fertility variant	0	--	Direct
Worm Phenotype (WP)	development variant	0	--	Direct
Worm Phenotype (WP)	morphology variant	0	--	Direct
Worm Phenotype (WP)	organism development variant	0	--	Direct
Worm Phenotype (WP)	organism morphology variant	0	--	Direct
Worm Phenotype (WP)	organ system physiology variant	0	--	Direct
Worm Phenotype (WP)	organism physiology variant	0	--	Direct
Worm Phenotype (WP)	organism homeostasis metabolism variant	0	--	Direct
Worm Phenotype (WP)	reproductive system physiology variant	0	--	Direct
Worm Phenotype (WP)	maternal sterile	0	--	Direct
Worm Phenotype (WP)	hermaphrodite sterile	0	--	Direct
Worm Phenotype (WP)	embryonic development variant	0	--	Direct
Worm Phenotype (WP)	hermaphrodite fertility variant	0	--	Direct
Worm Phenotype (WP)	developmental growth variant	0	--	Direct
Worm Phenotype (WP)	hermaphrodite fertility reduced	0	--	Direct
Worm Phenotype (WP)	fertility reduced	0	--	Direct
Worm Phenotype (WP)	protein acetylation variant	0	--	Direct
Worm Phenotype (WP)	rays displaced	0.0000000000006544	--	Direct
Worm Phenotype (WP)	protein metabolism variant	0.000000000009886	--	Direct
Worm Phenotype (WP)	sexually dimorphic morphology variant	0.00000001449	--	Direct
Worm Phenotype (WP)	organism UV response variant	0.000004562	--	Direct
Worm Phenotype (WP)	male nervous system morphology variant	0.00003736	--	Direct
Worm Phenotype (WP)	light response variant	0.00004669	--	Direct
Worm Phenotype (WP)	gene expression variant	0.00009084	--	Direct
Worm Phenotype (WP)	organ system development variant	0.007914	--	Inherited
Worm Phenotype (WP)	behavior variant	0.02839	--	Inherited
Worm Phenotype (WP)	physiology variant	1	--	Inherited
Worm Phenotype (WP)	sterile	1	--	Inherited
Worm Phenotype (WP)	larval development variant	0	Least Informative	Direct
Worm Phenotype (WP)	larval growth variant	0	Least Informative	Direct
Worm Phenotype (WP)	cell physiology variant	0.00001384	Least Informative	Direct
Worm Phenotype (WP)	organ system morphology variant	0.0007766	Least Informative	Direct
Worm Phenotype (WP)	organism metabolism processing variant	0.0009659	Least Informative	Direct
Worm Phenotype (WP)	organism behavior variant	0.02745	Least Informative	Inherited
Worm Phenotype (WP)	organism environmental stimulus response variant	0.1302	Least Informative	Inherited
Worm Phenotype (WP)	sterile progeny	0	Moderately Informative	Direct
Worm Phenotype (WP)	metabolic pathway variant	0.0000000001815	Moderately Informative	Direct
Worm Phenotype (WP)	protein expression variant	0.0000000008383	Moderately Informative	Direct
Worm Phenotype (WP)	cell homeostasis metabolism variant	0.00000001346	Moderately Informative	Direct
Worm Phenotype (WP)	nervous system morphology variant	0.0000005635	Moderately Informative	Direct
Worm Phenotype (WP)	reproductive system development variant	0.1789	Moderately Informative	Inherited
Worm Phenotype (WP)	organism stress response variant	0.2239	Moderately Informative	Inherited
Worm Phenotype (WP)	protein modification variant	0	Informative	Direct
Worm Phenotype (WP)	male morphology variant	0.000000009385	Informative	Direct
Worm Phenotype (WP)	sensillum morphology variant	0.00000001822	Informative	Direct
Worm Phenotype (WP)	vulva development variant	0.0002504	Informative	Direct
Worm Phenotype (WP)	spontaneous mutation rate increased	0.00000002361	Highly Informative	Direct
Worm Phenotype (WP)	organism UV hypersensitive	0.000001437	Highly Informative	Direct
Worm Phenotype (WP)	male ray morphology variant	0.001058	Highly Informative	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

YP

Yeast Phenotype (YP)

	YP term	FDR (all)	SDYP (four levels)	Annotation (direct or inherited)
Yeast Phenotype (YP)	cellular processes	0	--	Direct
Yeast Phenotype (YP)	stress resistance	0	--	Direct
Yeast Phenotype (YP)	resistance to chemicals	0	Least Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

FA

Fly Anatomy (FA)

	FA term	FDR (all)	SDFA (four levels)	Annotation (direct or inherited)
Fly Anatomy (FA)	organism	0	--	Direct
Fly Anatomy (FA)	tagma	0	--	Direct
Fly Anatomy (FA)	embryonic/larval nervous system	0	--	Direct
Fly Anatomy (FA)	adult nervous system	0	--	Direct
Fly Anatomy (FA)	organ system	0	--	Direct
Fly Anatomy (FA)	multicellular structure	0	--	Direct
Fly Anatomy (FA)	somatic cell	0	--	Direct
Fly Anatomy (FA)	anatomical structure	1	--	Inherited
Fly Anatomy (FA)	material anatomical entity	1	--	Inherited
Fly Anatomy (FA)	anterior-posterior subdivision of organism	1	--	Inherited
Fly Anatomy (FA)	larva	0	Least Informative	Direct
Fly Anatomy (FA)	adult	0	Least Informative	Direct
Fly Anatomy (FA)	nervous system	0	Least Informative	Direct
Fly Anatomy (FA)	cell	0	Least Informative	Direct
Fly Anatomy (FA)	organism subdivision	0	Least Informative	Direct
Fly Anatomy (FA)	adult tagma	0	Moderately Informative	Direct
Fly Anatomy (FA)	neuron	0	Moderately Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

ZA

Zebrafish Anatomy (ZA)

	ZA term	FDR (all)	SDZA (four levels)	Annotation (direct or inherited)
Zebrafish Anatomy (ZA)	whole organism	0	--	Direct
Zebrafish Anatomy (ZA)	anatomical system	0	--	Direct
Zebrafish Anatomy (ZA)	cavitated compound organ	0	--	Direct
Zebrafish Anatomy (ZA)	anatomical group	0	--	Direct
Zebrafish Anatomy (ZA)	lateral line	0.000005644	--	Direct
Zebrafish Anatomy (ZA)	peripheral nervous system	0.0002911	--	Direct
Zebrafish Anatomy (ZA)	fin	0.0009099	--	Direct
Zebrafish Anatomy (ZA)	anatomical structure	1	--	Inherited
Zebrafish Anatomy (ZA)	compound organ	0	Least Informative	Direct
Zebrafish Anatomy (ZA)	organism subdivision	0	Least Informative	Direct
Zebrafish Anatomy (ZA)	multi-tissue structure	0	Least Informative	Direct
Zebrafish Anatomy (ZA)	nervous system	0.3164	Least Informative	Inherited
Zebrafish Anatomy (ZA)	sensory system	0.1032	Moderately Informative	Inherited
Zebrafish Anatomy (ZA)	portion of tissue	0.2157	Moderately Informative	Inherited
Zebrafish Anatomy (ZA)	post-vent region	0	Informative	Direct
Zebrafish Anatomy (ZA)	surface structure	0.0251	Informative	Inherited
Zebrafish Anatomy (ZA)	lateral line system	0.00006805	Highly Informative	Direct
Zebrafish Anatomy (ZA)	median fin	0.0001196	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

XA

Xenopus Anatomy (XA)

	XA term	FDR (all)	SDXA (four levels)	Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)	anatomical structure	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical group	0	--	Direct
Xenopus ANatomical entity (XAN)	organism subdivision	0	--	Direct
Xenopus ANatomical entity (XAN)	compound organ	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical region	0	--	Direct
Xenopus ANatomical entity (XAN)	multicellular anatomical structure	0	--	Direct
Xenopus ANatomical entity (XAN)	whole organism	1	--	Inherited
Xenopus ANatomical entity (XAN)	tissue	0	Least Informative	Direct
Xenopus ANatomical entity (XAN)	cavitated compound organ	0	Least Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

AP

Arabidopsis Plant Ontology (AP)

	AP term	FDR (all)	SDAP (four levels)	Annotation (direct or inherited)
Plant ANatomical entity (PAN)	shoot system	0	--	Direct
Plant ANatomical entity (PAN)	collective plant structure	0	--	Direct
Plant ANatomical entity (PAN)	plant structure	1	--	Inherited
Plant ANatomical entity (PAN)	collective plant organ structure	1	--	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

EC

Enzyme Commission (EC)

	EC term	FDR (all)	SDEC (four levels)	Annotation (direct or inherited)
Enzyme Commission (EC)	Histone deacetylase	0	--	Direct
Enzyme Commission (EC)	Formimidoylglutamase	0	--	Direct
Enzyme Commission (EC)	Acetylputrescine deacetylase	0.0000000000008091	--	Direct
Enzyme Commission (EC)	Agmatinase	0.00000000001088	--	Direct
Enzyme Commission (EC)	Arginase	0.00000000003925	--	Direct
Enzyme Commission (EC)	Acetylspermidine deacetylase	0.000000004681	--	Direct
Enzyme Commission (EC)	Hydrolases	0	Least Informative	Direct
Enzyme Commission (EC)	Acting on carbon-nitrogen bonds, other than peptide bonds	0	Moderately Informative	Direct
Enzyme Commission (EC)	In linear amides	1	Informative	Inherited
Enzyme Commission (EC)	In linear amidines	0	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

KW

UniProtKB KeyWords (KW)

	KW term	FDR (all)	SDKW (four levels)	Annotation (direct or inherited)
Biological process	Acetoin catabolism	0	Moderately Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

CD

CTD Diseases (CD)

	CD term	FDR (all)	SDCD (four levels)	Annotation (direct or inherited)
CTD Diseases (CD)	Hypertension, Pulmonary	0.0000677	--	Direct
CTD Diseases (CD)	Lung Diseases	0.000255	--	Direct
CTD Diseases (CD)	Respiratory Tract Diseases	0.0005666	Moderately Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

CC

CTD Chemicals (CC)

	CC term	FDR (all)	SDCC (four levels)	Annotation (direct or inherited)
CTD Chemicals (CC)	Benzene Derivatives	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds, 1-Ring	0	--	Direct
CTD Chemicals (CC)	Hydrocarbons	0	--	Direct
CTD Chemicals (CC)	Hydrocarbons, Aromatic	0	--	Direct
CTD Chemicals (CC)	Hydrocarbons, Cyclic	0	--	Direct
CTD Chemicals (CC)	Inorganic Chemicals	0	--	Direct
CTD Chemicals (CC)	Organic Chemicals	0	--	Direct
CTD Chemicals (CC)	Polycyclic Compounds	0	--	Direct
CTD Chemicals (CC)	trapoxin B	0.00000000003533	--	Direct
CTD Chemicals (CC)	ginsenoside Rh2	0.000000004077	--	Direct
CTD Chemicals (CC)	mocetinostat	0.00000001134	--	Direct
CTD Chemicals (CC)	polyphenon E	0.0000001256	--	Direct
CTD Chemicals (CC)	Crotalid Venoms	0.0000001684	--	Direct
CTD Chemicals (CC)	methoxyacetic acid	0.000000967	--	Direct
CTD Chemicals (CC)	Viper Venoms	0.000001381	--	Direct
CTD Chemicals (CC)	Heptanes	0.00001086	--	Direct
CTD Chemicals (CC)	Prostaglandins D	0.00003343	--	Direct
CTD Chemicals (CC)	Estradiol	0.00004233	--	Direct
CTD Chemicals (CC)	Estradiol Congeners	0.00005435	--	Direct
CTD Chemicals (CC)	Isocyanates	0.0004179	--	Direct
CTD Chemicals (CC)	Aniline Compounds	0.0004189	--	Direct
CTD Chemicals (CC)	Gonadal Hormones	0.0006939	--	Direct
CTD Chemicals (CC)	Hormones, Hormone Substitutes, and Hormone Antagonists	0.0008657	--	Direct
CTD Chemicals (CC)	Physiological Effects of Drugs	0.0008912	--	Direct
CTD Chemicals (CC)	Isoquinolines	0.001256	--	Inherited
CTD Chemicals (CC)	Chromones	0.001866	--	Inherited
CTD Chemicals (CC)	Berberine Alkaloids	0.002907	--	Inherited
CTD Chemicals (CC)	Pharmacologic Actions	0.02214	--	Inherited
CTD Chemicals (CC)	Benzamides	0.06864	--	Inherited
CTD Chemicals (CC)	Eicosanoids	0.09945	--	Inherited
CTD Chemicals (CC)	Fatty Acids	0.1101	--	Inherited
CTD Chemicals (CC)	Lipids	0.1664	--	Inherited
CTD Chemicals (CC)	Carboxylic Acids	0.4191	--	Inherited
CTD Chemicals (CC)	Pyrans	0.4274	--	Inherited
CTD Chemicals (CC)	Heterocyclic Compounds, 2-Ring	0.4484	--	Inherited
CTD Chemicals (CC)	Glycosides	0.5813	--	Inherited
CTD Chemicals (CC)	Heterocyclic Compounds, Fused-Ring	0.7597	--	Inherited
CTD Chemicals (CC)	Toxins, Biological	0.9055	--	Inherited
CTD Chemicals (CC)	Estrenes	1	--	Inherited
CTD Chemicals (CC)	Hormones	1	--	Inherited
CTD Chemicals (CC)	Autacoids	1	--	Inherited
CTD Chemicals (CC)	Steroids	1	--	Inherited
CTD Chemicals (CC)	Prostaglandin D2	1	--	Inherited
CTD Chemicals (CC)	Phenols	0	Least Informative	Direct
CTD Chemicals (CC)	Fused-Ring Compounds	0.008685	Least Informative	Inherited
CTD Chemicals (CC)	Hydrocarbons, Acyclic	0.01074	Least Informative	Inherited
CTD Chemicals (CC)	Amides	0.02083	Least Informative	Inherited
CTD Chemicals (CC)	Sulfur Compounds	0.03034	Least Informative	Inherited
CTD Chemicals (CC)	Amines	0.03187	Least Informative	Inherited
CTD Chemicals (CC)	Chemical Actions and Uses	0.03512	Least Informative	Inherited
CTD Chemicals (CC)	Biological Factors	0.05292	Least Informative	Inherited
CTD Chemicals (CC)	Complex Mixtures	0.08052	Least Informative	Inherited
CTD Chemicals (CC)	Fatty Acids, Volatile	0.08899	Least Informative	Inherited
CTD Chemicals (CC)	Pyrimidines	0.08964	Least Informative	Inherited
CTD Chemicals (CC)	Acids, Carbocyclic	0.1464	Least Informative	Inherited
CTD Chemicals (CC)	Acids, Acyclic	0.1687	Least Informative	Inherited
CTD Chemicals (CC)	Terpenes	0.1687	Least Informative	Inherited
CTD Chemicals (CC)	Benzopyrans	0.2572	Least Informative	Inherited
CTD Chemicals (CC)	Carbohydrates	0.6559	Least Informative	Inherited
CTD Chemicals (CC)	Catechols	0.0001652	Moderately Informative	Direct
CTD Chemicals (CC)	Anilides	0.0003044	Moderately Informative	Direct
CTD Chemicals (CC)	Flavonoids	0.001808	Moderately Informative	Inherited
CTD Chemicals (CC)	Heterocyclic Compounds, 4 or More Rings	0.005903	Moderately Informative	Inherited
CTD Chemicals (CC)	Estranes	0.01253	Moderately Informative	Inherited
CTD Chemicals (CC)	Inflammation Mediators	0.01404	Moderately Informative	Inherited
CTD Chemicals (CC)	Organometallic Compounds	0.01665	Moderately Informative	Inherited
CTD Chemicals (CC)	Fatty Acids, Unsaturated	0.01904	Moderately Informative	Inherited
CTD Chemicals (CC)	Acetates	0.02461	Moderately Informative	Inherited
CTD Chemicals (CC)	Alkaloids	0.02905	Moderately Informative	Inherited
CTD Chemicals (CC)	Alkanes	0.2072	Moderately Informative	Inherited
CTD Chemicals (CC)	Benzoates	0.3009	Moderately Informative	Inherited
CTD Chemicals (CC)	Gonadal Steroid Hormones	1	Moderately Informative	Inherited
CTD Chemicals (CC)	Diarylheptanoids	0.0000004826	Informative	Direct
CTD Chemicals (CC)	Saponins	0.000252	Informative	Direct
CTD Chemicals (CC)	Boron Compounds	0.0005283	Informative	Direct
CTD Chemicals (CC)	Prostaglandins	0.0006472	Informative	Direct
CTD Chemicals (CC)	Isothiocyanates	0.0009763	Informative	Direct
CTD Chemicals (CC)	Benzylisoquinolines	0.001047	Informative	Inherited
CTD Chemicals (CC)	Venoms	0.001058	Informative	Inherited
CTD Chemicals (CC)	Triterpenes	0.01189	Informative	Inherited
CTD Chemicals (CC)	Hydroquinones	0.01242	Informative	Inherited
CTD Chemicals (CC)	Chromans	0.159	Informative	Inherited
CTD Chemicals (CC)	monomethylarsonous acid	0.000000001018	Highly Informative	Direct
CTD Chemicals (CC)	Curcumin	0.000000138	Highly Informative	Direct
CTD Chemicals (CC)	Benzothiepins	0.0000002601	Highly Informative	Direct
CTD Chemicals (CC)	Berberine	0.000003066	Highly Informative	Direct
CTD Chemicals (CC)	sulforafan	0.000008658	Highly Informative	Direct
CTD Chemicals (CC)	Intercellular Signaling Peptides and Proteins	0.000009039	Highly Informative	Direct
CTD Chemicals (CC)	15-deoxy-delta(12,14)-prostaglandin J2	0.000009086	Highly Informative	Direct
CTD Chemicals (CC)	Ginsenosides	0.00002691	Highly Informative	Direct
CTD Chemicals (CC)	hydroquinone	0.00004658	Highly Informative	Direct
CTD Chemicals (CC)	Snake Venoms	0.0001627	Highly Informative	Direct
CTD Chemicals (CC)	Catechin	0.3723	Highly Informative	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

Distribution on sTOL

Plot distribution on species Tree Of Life (sTOL) for this domain, i.e., present or absent across genomes/tips

Plot tree as:

Download Newick format tree:

Browsing in TREE OF LIFE:

(show help)

LINKOUT

Arginase/deacetylase superfamily