CoA-dependent acyltransferases superfamily

DO

Disease Ontology (DO)

	DO term	FDR (all)	SDDO (four levels)	Annotation (direct or inherited)
Disease Ontology (DO)	autoimmune disease of urogenital tract	0.00001077	--	Direct
Disease Ontology (DO)	hepatobiliary disease	0.002651	--	Inherited
Disease Ontology (DO)	hypersensitivity reaction disease	0.03732	--	Inherited
Disease Ontology (DO)	liver cirrhosis	0.05072	--	Inherited
Disease Ontology (DO)	immune system disease	0.1057	--	Inherited
Disease Ontology (DO)	disease of anatomical entity	0.1754	--	Inherited
Disease Ontology (DO)	gastrointestinal system disease	0.02476	Moderately Informative	Inherited
Disease Ontology (DO)	hypersensitivity reaction type II disease	0.02602	Moderately Informative	Inherited
Disease Ontology (DO)	liver disease	0.002256	Informative	Inherited
Disease Ontology (DO)	primary biliary cirrhosis	0.00001077	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

HP

Human Phenotype (HP)

	HP term	FDR (all)	SDHP (four levels)	Annotation (direct or inherited)
Phenotypic Abnormality (PA)	Abnormality of the nervous system	0	--	Direct
Phenotypic Abnormality (PA)	Abnormality of nervous system physiology	0	Least Informative	Direct
Phenotypic Abnormality (PA)	Abnormality of higher mental function	0.3949	Moderately Informative	Inherited
Phenotypic Abnormality (PA)	Reduced consciousness/confusion	0.05126	Informative	Inherited
Phenotypic Abnormality (PA)	Coma	0.0006131	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

MP

Mouse Phenotype (MP)

	MP term	FDR (all)	SDMP (four levels)	Annotation (direct or inherited)
Mammalian Phenotype (MP)	homeostasis/metabolism phenotype	0	--	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

WP

Worm Phenotype (WP)

	WP term	FDR (all)	SDWP (four levels)	Annotation (direct or inherited)
Worm Phenotype (WP)	embryonic lethal	0	--	Direct
Worm Phenotype (WP)	lethal	0	--	Direct
Worm Phenotype (WP)	fertility variant	0	--	Direct
Worm Phenotype (WP)	development variant	0	--	Direct
Worm Phenotype (WP)	organism development variant	0	--	Direct
Worm Phenotype (WP)	organ system physiology variant	0	--	Direct
Worm Phenotype (WP)	reproductive system physiology variant	0	--	Direct
Worm Phenotype (WP)	maternal sterile	0	--	Direct
Worm Phenotype (WP)	hermaphrodite sterile	0	--	Direct
Worm Phenotype (WP)	embryonic development variant	0	--	Direct
Worm Phenotype (WP)	hermaphrodite fertility variant	0	--	Direct
Worm Phenotype (WP)	hermaphrodite fertility reduced	0	--	Direct
Worm Phenotype (WP)	fertility reduced	0	--	Direct
Worm Phenotype (WP)	larval physiology variant	0.008834	--	Inherited
Worm Phenotype (WP)	postembryonic development variant	0.599	--	Inherited
Worm Phenotype (WP)	organism homeostasis metabolism variant	0.8082	--	Inherited
Worm Phenotype (WP)	organism physiology variant	0.8267	--	Inherited
Worm Phenotype (WP)	physiology variant	1	--	Inherited
Worm Phenotype (WP)	sterile	1	--	Inherited
Worm Phenotype (WP)	organism metabolism processing variant	0.0003892	Least Informative	Direct
Worm Phenotype (WP)	larval development variant	0.5051	Least Informative	Inherited
Worm Phenotype (WP)	dauer larva physiology variant	1	Informative	Inherited
Worm Phenotype (WP)	dauer development variant	0.000251	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

YP

Yeast Phenotype (YP)

	YP term	FDR (all)	SDYP (four levels)	Annotation (direct or inherited)
Yeast Phenotype (YP)	cellular processes	0	--	Direct
Yeast Phenotype (YP)	stress resistance	0	--	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

FA

Fly Anatomy (FA)

	FA term	FDR (all)	SDFA (four levels)	Annotation (direct or inherited)
Fly Anatomy (FA)	skeletal muscle of mesothorax	0.0001705	--	Direct
Fly Anatomy (FA)	skeletal muscle of thorax	0.0002103	--	Direct
Fly Anatomy (FA)	adult somatic muscle	0.0003447	--	Direct
Fly Anatomy (FA)	adult muscle system	0.0004666	--	Direct
Fly Anatomy (FA)	somatic muscle	0.008766	--	Inherited
Fly Anatomy (FA)	muscle cell	0.01027	--	Inherited
Fly Anatomy (FA)	adult mesothoracic segment	0.2081	--	Inherited
Fly Anatomy (FA)	adult thoracic segment	0.2277	--	Inherited
Fly Anatomy (FA)	adult thorax	0.2318	--	Inherited
Fly Anatomy (FA)	mesothoracic segment	0.2576	--	Inherited
Fly Anatomy (FA)	thoracic segment	0.2924	--	Inherited
Fly Anatomy (FA)	somatic cell	0.4506	--	Inherited
Fly Anatomy (FA)	segment	0.4562	--	Inherited
Fly Anatomy (FA)	organ system	0.5466	--	Inherited
Fly Anatomy (FA)	tagma	0.7013	--	Inherited
Fly Anatomy (FA)	organism	0.8465	--	Inherited
Fly Anatomy (FA)	multicellular structure	0.9599	--	Inherited
Fly Anatomy (FA)	anatomical structure	1	--	Inherited
Fly Anatomy (FA)	material anatomical entity	1	--	Inherited
Fly Anatomy (FA)	anterior-posterior subdivision of organism	1	--	Inherited
Fly Anatomy (FA)	cell	0.559	Least Informative	Inherited
Fly Anatomy (FA)	organism subdivision	0.7025	Least Informative	Inherited
Fly Anatomy (FA)	adult	0.7259	Least Informative	Inherited
Fly Anatomy (FA)	thorax	0.2992	Moderately Informative	Inherited
Fly Anatomy (FA)	adult segment	0.3224	Moderately Informative	Inherited
Fly Anatomy (FA)	adult tagma	0.5311	Moderately Informative	Inherited
Fly Anatomy (FA)	syncytium	0.008766	Informative	Inherited
Fly Anatomy (FA)	muscle system	0.01219	Informative	Inherited
Fly Anatomy (FA)	flight muscle	0.0001565	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

ZA

Zebrafish Anatomy (ZA)

	ZA term	FDR (all)	SDZA (four levels)	Annotation (direct or inherited)
Zebrafish Anatomy (ZA)	whole organism	0	--	Direct
Zebrafish Anatomy (ZA)	anatomical system	0	--	Direct
Zebrafish Anatomy (ZA)	anatomical group	0	--	Direct
Zebrafish Anatomy (ZA)	anatomical structure	1	--	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

XA

Xenopus Anatomy (XA)

	XA term	FDR (all)	SDXA (four levels)	Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)	trunk region	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical structure	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical group	0	--	Direct
Xenopus ANatomical entity (XAN)	organism subdivision	0	--	Direct
Xenopus ANatomical entity (XAN)	compound organ	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical cluster	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical region	0	--	Direct
Xenopus ANatomical entity (XAN)	multicellular anatomical structure	0	--	Direct
Xenopus ANatomical entity (XAN)	whole organism	1	--	Inherited
Xenopus ANatomical entity (XAN)	trunk	0	Least Informative	Direct
Xenopus ANatomical entity (XAN)	tissue	0	Least Informative	Direct
Xenopus ANatomical entity (XAN)	cavitated compound organ	0	Least Informative	Direct

	XA term	FDR (all)	SDXA (four levels)	Annotation (direct or inherited)
Xenopus DEvelopment stage (XDE)	tadpole stage	0	--	Direct
Xenopus DEvelopment stage (XDE)	post-embryonic stage	0	Least Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

AP

Arabidopsis Plant Ontology (AP)

	AP term	FDR (all)	SDAP (four levels)	Annotation (direct or inherited)
Plant ANatomical entity (PAN)	collective plant structure	0	--	Direct
Plant ANatomical entity (PAN)	plant structure	1	--	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

EC

Enzyme Commission (EC)

	EC term	FDR (all)	SDEC (four levels)	Annotation (direct or inherited)
Enzyme Commission (EC)	Oxoglutarate dehydrogenase (succinyl-transferring)	0	--	Direct
Enzyme Commission (EC)	Transferases	0	--	Direct
Enzyme Commission (EC)	2-hydroxy-3-oxoadipate synthase	0	--	Direct
Enzyme Commission (EC)	Acyltransferases	0	--	Direct
Enzyme Commission (EC)	Dihydrolipoyllysine-residue acetyltransferase	0	--	Direct
Enzyme Commission (EC)	Diacylglycerol O-acyltransferase	0	--	Direct
Enzyme Commission (EC)	Carnitine O-palmitoyltransferase	0	--	Direct
Enzyme Commission (EC)	Chloramphenicol O-acetyltransferase	0	--	Direct
Enzyme Commission (EC)	Dihydrolipoyllysine-residue succinyltransferase	0	--	Direct
Enzyme Commission (EC)	2-oxoglutarate decarboxylase	0	--	Direct
Enzyme Commission (EC)	N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase	0	--	Direct
Enzyme Commission (EC)	L-2-aminoadipate reductase	5.111e-16	--	Direct
Enzyme Commission (EC)	L-aminoadipate-semialdehyde dehydrogenase	0.000000000000007987	--	Direct
Enzyme Commission (EC)	Phenylalanine racemase (ATP-hydrolyzing)	0.0000000000002003	--	Direct
Enzyme Commission (EC)	Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase	0.000000000001861	--	Direct
Enzyme Commission (EC)	Choline O-acetyltransferase	0.00000000002274	--	Direct
Enzyme Commission (EC)	Carnitine O-acetyltransferase	0.00000000002274	--	Direct
Enzyme Commission (EC)	With a disulfide as acceptor	0.0000000005166	--	Direct
Enzyme Commission (EC)	Phenolphthiocerol/phthiocerol/phthiodiolone dimycocerosyl transferase	0.00000004064	--	Direct
Enzyme Commission (EC)	Carnitine O-octanoyltransferase	0.0000004904	--	Direct
Enzyme Commission (EC)	Transferring aldehyde or ketonic groups	0.005037	--	Inherited
Enzyme Commission (EC)	Forming carbon-nitrogen bonds	1	--	Inherited
Enzyme Commission (EC)	Oxidoreductases	1	Least Informative	Inherited
Enzyme Commission (EC)	Lyases	1	Least Informative	Inherited
Enzyme Commission (EC)	Transferring groups other than amino-acyl groups	0	Moderately Informative	Direct
Enzyme Commission (EC)	Carbon-carbon lyases	0.1925	Moderately Informative	Inherited
Enzyme Commission (EC)	Isomerases	1	Moderately Informative	Inherited
Enzyme Commission (EC)	Ligases	1	Moderately Informative	Inherited
Enzyme Commission (EC)	Acting on the aldehyde or oxo group of donors	0.000001423	Informative	Direct
Enzyme Commission (EC)	Racemases and epimerases	0.003381	Informative	Inherited
Enzyme Commission (EC)	Carboxy-lyases	0.02916	Informative	Inherited
Enzyme Commission (EC)	Acid--amino-acid ligases (peptide synthases)	0.09337	Informative	Inherited
Enzyme Commission (EC)	Lovastatin nonaketide synthase	0.00001779	Highly Informative	Direct
Enzyme Commission (EC)	Acting on amino acids and derivatives	0.00005874	Highly Informative	Direct
Enzyme Commission (EC)	With NAD(+) or NADP(+) as acceptor	1	Highly Informative	Inherited
Enzyme Commission (EC)	Transketolases and transaldolases	1	Highly Informative	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

CC

CTD Chemicals (CC)

	CC term	FDR (all)	SDCC (four levels)	Annotation (direct or inherited)
CTD Chemicals (CC)	Heterocyclic Compounds, Fused-Ring	0	--	Direct
CTD Chemicals (CC)	Fatty Acids	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds, 1-Ring	0	--	Direct
CTD Chemicals (CC)	Hydrocarbons	0	--	Direct
CTD Chemicals (CC)	Inorganic Chemicals	0	--	Direct
CTD Chemicals (CC)	Lipids	0	--	Direct
CTD Chemicals (CC)	Organic Chemicals	0	--	Direct
CTD Chemicals (CC)	Oleic Acids	0.0001616	--	Direct
CTD Chemicals (CC)	Hydrocarbons, Fluorinated	0.0001927	--	Direct
CTD Chemicals (CC)	Cholanes	0.0003351	--	Direct
CTD Chemicals (CC)	Cholic Acids	0.0003351	--	Direct
CTD Chemicals (CC)	Bile Acids and Salts	0.0003656	--	Direct
CTD Chemicals (CC)	Polyenes	0.02248	--	Inherited
CTD Chemicals (CC)	Cyclohexanes	0.03177	--	Inherited
CTD Chemicals (CC)	Pigments, Biological	0.04638	--	Inherited
CTD Chemicals (CC)	Hydrocarbons, Alicyclic	0.06391	--	Inherited
CTD Chemicals (CC)	Retinoids	0.06704	--	Inherited
CTD Chemicals (CC)	Cycloparaffins	0.1787	--	Inherited
CTD Chemicals (CC)	Alkenes	0.276	--	Inherited
CTD Chemicals (CC)	Polycyclic Compounds	0.3961	--	Inherited
CTD Chemicals (CC)	Carboxylic Acids	0.518	--	Inherited
CTD Chemicals (CC)	Cyclohexenes	0.7428	--	Inherited
CTD Chemicals (CC)	Hydrocarbons, Cyclic	0.9702	--	Inherited
CTD Chemicals (CC)	Steroids	1	--	Inherited
CTD Chemicals (CC)	Hydrocarbons, Acyclic	0.04285	Least Informative	Inherited
CTD Chemicals (CC)	Terpenes	0.07757	Least Informative	Inherited
CTD Chemicals (CC)	Biological Factors	0.1085	Least Informative	Inherited
CTD Chemicals (CC)	Macrocyclic Compounds	0.1209	Least Informative	Inherited
CTD Chemicals (CC)	Acids, Acyclic	0.2587	Least Informative	Inherited
CTD Chemicals (CC)	Fused-Ring Compounds	0.8732	Least Informative	Inherited
CTD Chemicals (CC)	Fatty Acids, Unsaturated	0.049	Moderately Informative	Inherited
CTD Chemicals (CC)	Hydrocarbons, Halogenated	0.06429	Moderately Informative	Inherited
CTD Chemicals (CC)	Carotenoids	0.4829	Moderately Informative	Inherited
CTD Chemicals (CC)	Caprylates	0.00002827	Informative	Direct
CTD Chemicals (CC)	Deoxycholic Acid	0.0001045	Informative	Direct
CTD Chemicals (CC)	Fluorocarbons	0.0001404	Informative	Direct
CTD Chemicals (CC)	Triazines	0.0008307	Informative	Direct
CTD Chemicals (CC)	Fatty Acids, Monounsaturated	0.001172	Informative	Inherited
CTD Chemicals (CC)	perfluorooctanoic acid	0.000007927	Highly Informative	Direct
CTD Chemicals (CC)	Isotretinoin	0.0001289	Highly Informative	Direct
CTD Chemicals (CC)	Atrazine	0.0004141	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

Distribution on sTOL

Plot distribution on species Tree Of Life (sTOL) for this domain, i.e., present or absent across genomes/tips

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CoA-dependent acyltransferases superfamily