dcGO - A comprehensive domain-centric ontology resource for post-genomic research on functions, phenotypes, diseases and more   
  
  

TK C-terminal domain-like superfamily

Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   TK C-terminal domain-like [ 52921]
Superfamily:   TK C-terminal domain-like [ 52922] (3)
Families:   Transketolase C-terminal domain-like [ 52923] (2)
  Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain [ 52926] (4)
  Pyruvate-ferredoxin oxidoreductase, PFOR, domain II [ 52931]

HP

Human Phenotype (HP)

HP term FDR (all) SDHP (four levels) Annotation (direct or inherited)
Mode of Inheritance (MI)Autosomal recessive inheritance0--Direct
 
HP term FDR (all) SDHP (four levels) Annotation (direct or inherited)
Phenotypic Abnormality (PA)Muscular hypotonia0--Direct
Phenotypic Abnormality (PA)Abnormal muscle physiology0--Direct
Phenotypic Abnormality (PA)Abnormality of the musculature0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormal muscle tone0Moderately InformativeDirect
Phenotypic Abnormality (PA)Generalized hypotonia0Highly InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

WP

Worm Phenotype (WP)

WP term FDR (all) SDWP (four levels) Annotation (direct or inherited)
Worm Phenotype (WP)growth variant0--Direct
Worm Phenotype (WP)slow growth0--Direct
Worm Phenotype (WP)developmental timing variant0--Direct
Worm Phenotype (WP)postembryonic development variant0--Direct
Worm Phenotype (WP)embryonic lethal0--Direct
Worm Phenotype (WP)lethal0--Direct
Worm Phenotype (WP)fertility variant0--Direct
Worm Phenotype (WP)transgene expression variant0--Direct
Worm Phenotype (WP)development variant0--Direct
Worm Phenotype (WP)morphology variant0--Direct
Worm Phenotype (WP)organism development variant0--Direct
Worm Phenotype (WP)organism morphology variant0--Direct
Worm Phenotype (WP)organ system physiology variant0--Direct
Worm Phenotype (WP)organism physiology variant0--Direct
Worm Phenotype (WP)organism homeostasis metabolism variant0--Direct
Worm Phenotype (WP)reproductive system physiology variant0--Direct
Worm Phenotype (WP)maternal sterile0--Direct
Worm Phenotype (WP)hermaphrodite sterile0--Direct
Worm Phenotype (WP)gene expression variant0--Direct
Worm Phenotype (WP)embryonic development variant0--Direct
Worm Phenotype (WP)hermaphrodite fertility variant0--Direct
Worm Phenotype (WP)hermaphrodite fertility reduced0--Direct
Worm Phenotype (WP)fertility reduced0--Direct
Worm Phenotype (WP)physiology variant1--Inherited
Worm Phenotype (WP)sterile1--Inherited
Worm Phenotype (WP)organism metabolism processing variant0Least InformativeDirect
Worm Phenotype (WP)general pace of development variant0Least InformativeDirect
Worm Phenotype (WP)retarded heterochronic variations0Least InformativeDirect
Worm Phenotype (WP)larval development variant0Least InformativeDirect
Worm Phenotype (WP)level of transgene expression variant0Moderately InformativeDirect
Worm Phenotype (WP)transgene expression increased0InformativeDirect

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YP

Yeast Phenotype (YP)

YP term FDR (all) SDYP (four levels) Annotation (direct or inherited)
Yeast Phenotype (YP)cellular processes0--Direct
Yeast Phenotype (YP)stress resistance0--Direct
Yeast Phenotype (YP)resistance to chemicals0Least InformativeDirect
Yeast Phenotype (YP)metabolism and growth0.252Least InformativeInherited
Yeast Phenotype (YP)nutrient utilization0.002472Moderately InformativeInherited
Yeast Phenotype (YP)utilization of nitrogen source0.0005799InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

XA

Xenopus Anatomy (XA)

XA term FDR (all) SDXA (four levels) Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)head region0--Direct
Xenopus ANatomical entity (XAN)trunk region0--Direct
Xenopus ANatomical entity (XAN)liver and biliary system0--Direct
Xenopus ANatomical entity (XAN)genital system0--Direct
Xenopus ANatomical entity (XAN)male genitalia0--Direct
Xenopus ANatomical entity (XAN)central nervous system0--Direct
Xenopus ANatomical entity (XAN)anatomical structure0--Direct
Xenopus ANatomical entity (XAN)anatomical group0--Direct
Xenopus ANatomical entity (XAN)male organism0--Direct
Xenopus ANatomical entity (XAN)primary germ layer0--Direct
Xenopus ANatomical entity (XAN)cell0--Direct
Xenopus ANatomical entity (XAN)organism subdivision0--Direct
Xenopus ANatomical entity (XAN)compound organ0--Direct
Xenopus ANatomical entity (XAN)egg0--Direct
Xenopus ANatomical entity (XAN)gonad0--Direct
Xenopus ANatomical entity (XAN)gamete0--Direct
Xenopus ANatomical entity (XAN)anatomical cluster0--Direct
Xenopus ANatomical entity (XAN)anatomical region0--Direct
Xenopus ANatomical entity (XAN)multicellular anatomical structure0--Direct
Xenopus ANatomical entity (XAN)anatomical system1--Inherited
Xenopus ANatomical entity (XAN)whole organism1--Inherited
Xenopus ANatomical entity (XAN)embryo0Least InformativeDirect
Xenopus ANatomical entity (XAN)urogenital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)nervous system0Least InformativeDirect
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)trunk0Least InformativeDirect
Xenopus ANatomical entity (XAN)tissue0Least InformativeDirect
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect
Xenopus ANatomical entity (XAN)ectoderm0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)germ cell0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)alimentary system0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)testis0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)viscus0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)solid compound organ0InformativeDirect
Xenopus ANatomical entity (XAN)liver0Highly InformativeDirect
Xenopus ANatomical entity (XAN)pancreas0.00009252Highly InformativeDirect
 
XA term FDR (all) SDXA (four levels) Annotation (direct or inherited)
Xenopus DEvelopment stage (XDE)tadpole stage0--Direct
Xenopus DEvelopment stage (XDE)metamorphosing tadpole stage0--Direct
Xenopus DEvelopment stage (XDE)NF stage0--Direct
Xenopus DEvelopment stage (XDE)post-embryonic stage0Least InformativeDirect
Xenopus DEvelopment stage (XDE)unspecified stage0Moderately InformativeDirect
Xenopus DEvelopment stage (XDE)climax stage0Moderately InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

AP

Arabidopsis Plant Ontology (AP)

AP term FDR (all) SDAP (four levels) Annotation (direct or inherited)
Plant ANatomical entity (PAN)phyllome0--Direct
Plant ANatomical entity (PAN)shoot system0--Direct
Plant ANatomical entity (PAN)plant organ0--Direct
Plant ANatomical entity (PAN)plant embryo0--Direct
Plant ANatomical entity (PAN)sporophyll0--Direct
Plant ANatomical entity (PAN)stamen0--Direct
Plant ANatomical entity (PAN)sepal0--Direct
Plant ANatomical entity (PAN)stem0--Direct
Plant ANatomical entity (PAN)perianth0--Direct
Plant ANatomical entity (PAN)calyx0--Direct
Plant ANatomical entity (PAN)androecium0--Direct
Plant ANatomical entity (PAN)plant axis0--Direct
Plant ANatomical entity (PAN)reproductive shoot system0--Direct
Plant ANatomical entity (PAN)multi-tissue plant structure0--Direct
Plant ANatomical entity (PAN)collective plant structure0--Direct
Plant ANatomical entity (PAN)plant structure1--Inherited
Plant ANatomical entity (PAN)collective plant organ structure1--Inherited
Plant ANatomical entity (PAN)whole plant0Least InformativeDirect
Plant ANatomical entity (PAN)microsporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)flower0Least InformativeDirect
Plant ANatomical entity (PAN)collective phyllome structure0Least InformativeDirect
Plant ANatomical entity (PAN)shoot axis0Least InformativeDirect
 
AP term FDR (all) SDAP (four levels) Annotation (direct or inherited)
Plant structure DEvelopment stage (PDE)whole plant development stage0--Direct
Plant structure DEvelopment stage (PDE)sporophyte vegetative stage0--Direct
Plant structure DEvelopment stage (PDE)flowering stage0--Direct
Plant structure DEvelopment stage (PDE)plant embryo stage0--Direct
Plant structure DEvelopment stage (PDE)collective plant organ structure development stage0--Direct
Plant structure DEvelopment stage (PDE)reproductive shoot system development stage0--Direct
Plant structure DEvelopment stage (PDE)flower development stage1--Inherited
Plant structure DEvelopment stage (PDE)life of whole plant stage1--Inherited
Plant structure DEvelopment stage (PDE)shoot system development stage1--Inherited
Plant structure DEvelopment stage (PDE)sporophyte development stage1--Inherited
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)seed development stage0.00001712InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

EC

Enzyme Commission (EC)

EC term FDR (all) SDEC (four levels) Annotation (direct or inherited)
Enzyme Commission (EC)With a disulfide as acceptor0--Direct
Enzyme Commission (EC)Transferases0--Direct
Enzyme Commission (EC)Transferring aldehyde or ketonic groups0--Direct
Enzyme Commission (EC)1-deoxy-D-xylulose-5-phosphate synthase0--Direct
Enzyme Commission (EC)Transketolase0.000000000005558--Direct
Enzyme Commission (EC)Pyruvate dehydrogenase (acetyl-transferring)0.000000001465--Direct
Enzyme Commission (EC)Oxidoreductases0.00197Least InformativeInherited
Enzyme Commission (EC)Acting on the aldehyde or oxo group of donors0InformativeDirect
Enzyme Commission (EC)With an iron-sulfur protein as acceptor0Highly InformativeDirect
Enzyme Commission (EC)Transketolases and transaldolases1Highly InformativeInherited

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CD

CTD Diseases (CD)

CD term FDR (all) SDCD (four levels) Annotation (direct or inherited)
CTD Diseases (CD)Brain Diseases0--Direct
CTD Diseases (CD)Central Nervous System Diseases0--Direct
CTD Diseases (CD)Metabolic Diseases0--Direct
CTD Diseases (CD)Nervous System Diseases0Least InformativeDirect
CTD Diseases (CD)Nutritional and Metabolic Diseases0Least InformativeDirect
CTD Diseases (CD)Brain Diseases, Metabolic0InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

CC

CTD Chemicals (CC)

CC term FDR (all) SDCC (four levels) Annotation (direct or inherited)
CTD Chemicals (CC)Heterocyclic Compounds, Fused-Ring0--Direct
CTD Chemicals (CC)Carboxylic Acids0--Direct
CTD Chemicals (CC)Fatty Acids0--Direct
CTD Chemicals (CC)Heterocyclic Compounds0--Direct
CTD Chemicals (CC)Heterocyclic Compounds, 1-Ring0--Direct
CTD Chemicals (CC)Heterocyclic Compounds, 2-Ring0--Direct
CTD Chemicals (CC)Inorganic Chemicals0--Direct
CTD Chemicals (CC)Lipids0--Direct
CTD Chemicals (CC)Organic Chemicals0--Direct
CTD Chemicals (CC)Pentanoic Acids0--Direct
CTD Chemicals (CC)Valerates0--Direct
CTD Chemicals (CC)Valproic Acid0--Direct
CTD Chemicals (CC)Retinoids0.09265--Inherited
CTD Chemicals (CC)Cyclohexenes0.09707--Inherited
CTD Chemicals (CC)Polyenes0.1045--Inherited
CTD Chemicals (CC)Alkenes0.109--Inherited
CTD Chemicals (CC)Cyclohexanes0.124--Inherited
CTD Chemicals (CC)Cycloparaffins0.1746--Inherited
CTD Chemicals (CC)Hydrocarbons, Alicyclic0.1746--Inherited
CTD Chemicals (CC)Pigments, Biological0.1776--Inherited
CTD Chemicals (CC)Hydrocarbons, Cyclic0.7197--Inherited
CTD Chemicals (CC)Hydrocarbons0.8181--Inherited
CTD Chemicals (CC)Polycyclic Compounds0.9893--Inherited
CTD Chemicals (CC)Acids, Acyclic0Least InformativeDirect
CTD Chemicals (CC)Elements0Least InformativeDirect
CTD Chemicals (CC)Fatty Acids, Volatile0Least InformativeDirect
CTD Chemicals (CC)Terpenes0.2471Least InformativeInherited
CTD Chemicals (CC)Hydrocarbons, Acyclic0.3266Least InformativeInherited
CTD Chemicals (CC)Biological Factors0.4049Least InformativeInherited
CTD Chemicals (CC)Macrocyclic Compounds0.5777Least InformativeInherited
CTD Chemicals (CC)Carotenoids0.0965Moderately InformativeInherited
CTD Chemicals (CC)Isotretinoin0.0001794Highly InformativeDirect

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Distribution on sTOL

Plot distribution on species Tree Of Life (sTOL) for this domain, i.e., present or absent across genomes/tips
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