Class II aaRS ABD-related superfamily

HP

Human Phenotype (HP)

	HP term	FDR (all)	SDHP (four levels)	Annotation (direct or inherited)
Phenotypic Abnormality (PA)	Abnormality of the musculature of the limbs	0.0003835	--	Direct
Phenotypic Abnormality (PA)	Abnormality of the musculature	0.165	Least Informative	Inherited
Phenotypic Abnormality (PA)	Abnormality of limbs	0.1652	Least Informative	Inherited
Phenotypic Abnormality (PA)	Abnormal skeletal muscle morphology	0.1792	Moderately Informative	Inherited

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WP

Worm Phenotype (WP)

	WP term	FDR (all)	SDWP (four levels)	Annotation (direct or inherited)
Worm Phenotype (WP)	growth variant	0	--	Direct
Worm Phenotype (WP)	slow growth	0	--	Direct
Worm Phenotype (WP)	developmental timing variant	0	--	Direct
Worm Phenotype (WP)	postembryonic development variant	0	--	Direct
Worm Phenotype (WP)	embryonic lethal	0	--	Direct
Worm Phenotype (WP)	lethal	0	--	Direct
Worm Phenotype (WP)	transgene expression variant	0	--	Direct
Worm Phenotype (WP)	development variant	0	--	Direct
Worm Phenotype (WP)	morphology variant	0	--	Direct
Worm Phenotype (WP)	organism development variant	0	--	Direct
Worm Phenotype (WP)	organ system physiology variant	0	--	Direct
Worm Phenotype (WP)	organism physiology variant	0	--	Direct
Worm Phenotype (WP)	organism homeostasis metabolism variant	0	--	Direct
Worm Phenotype (WP)	reproductive system physiology variant	0	--	Direct
Worm Phenotype (WP)	gene expression variant	0	--	Direct
Worm Phenotype (WP)	embryonic development variant	0	--	Direct
Worm Phenotype (WP)	oxygen response variant	0.00000000289	--	Direct
Worm Phenotype (WP)	receptor mediated endocytosis defective	0.00000002278	--	Direct
Worm Phenotype (WP)	hermaphrodite physiology variant	0.00000003837	--	Direct
Worm Phenotype (WP)	sexually dimorphic physiology variant	0.00000009973	--	Direct
Worm Phenotype (WP)	germ cell physiology variant	0.0000001672	--	Direct
Worm Phenotype (WP)	gonad morphology variant	0.0001205	--	Direct
Worm Phenotype (WP)	response to bacteria variant	0.0003088	--	Direct
Worm Phenotype (WP)	vesicle trafficking variant	0.0003436	--	Direct
Worm Phenotype (WP)	cell type morphology variant	0.0006393	--	Direct
Worm Phenotype (WP)	cell component morphology variant	0.0009961	--	Direct
Worm Phenotype (WP)	behavior variant	0.06728	--	Inherited
Worm Phenotype (WP)	gametogenesis variant	0.06776	--	Inherited
Worm Phenotype (WP)	physiology variant	1	--	Inherited
Worm Phenotype (WP)	organism metabolism processing variant	0	Least Informative	Direct
Worm Phenotype (WP)	general pace of development variant	0	Least Informative	Direct
Worm Phenotype (WP)	retarded heterochronic variations	0	Least Informative	Direct
Worm Phenotype (WP)	cell physiology variant	0.0000529	Least Informative	Direct
Worm Phenotype (WP)	cell morphology variant	0.003217	Least Informative	Inherited
Worm Phenotype (WP)	cell development variant	0.004602	Least Informative	Inherited
Worm Phenotype (WP)	organism environmental stimulus response variant	0.01639	Least Informative	Inherited
Worm Phenotype (WP)	organ system morphology variant	0.02122	Least Informative	Inherited
Worm Phenotype (WP)	organism behavior variant	0.06543	Least Informative	Inherited
Worm Phenotype (WP)	pattern of transgene expression variant	0	Moderately Informative	Direct
Worm Phenotype (WP)	endocytic transport variant	0.0000001932	Moderately Informative	Direct
Worm Phenotype (WP)	germ cell morphology variant	0.00002907	Moderately Informative	Direct
Worm Phenotype (WP)	feeding behavior variant	0.0001003	Moderately Informative	Direct
Worm Phenotype (WP)	germ cell differentiation variant	0.0001898	Moderately Informative	Direct
Worm Phenotype (WP)	early embryonic lethal	0.0002566	Moderately Informative	Direct
Worm Phenotype (WP)	organism stress response variant	0.0006112	Moderately Informative	Direct
Worm Phenotype (WP)	reproductive system morphology variant	0.002277	Moderately Informative	Inherited
Worm Phenotype (WP)	level of transgene expression variant	0.3236	Moderately Informative	Inherited
Worm Phenotype (WP)	hypoxia response variant	0.000000001139	Informative	Direct
Worm Phenotype (WP)	oocyte physiology variant	0.00000002874	Informative	Direct
Worm Phenotype (WP)	endocytic transport defect	0.0000001692	Informative	Direct
Worm Phenotype (WP)	avoids bacterial lawn	0.000009031	Informative	Direct
Worm Phenotype (WP)	transgene expression increased	0.00003302	Informative	Direct
Worm Phenotype (WP)	germ cell cytoplasmic morphology variant	0.005889	Informative	Inherited
Worm Phenotype (WP)	hypoxia resistant	0.0000000000002196	Highly Informative	Direct
Worm Phenotype (WP)	cell differentiation variant	0.00001756	Highly Informative	Direct
Worm Phenotype (WP)	cytoplasmic processing body variant	0.00003332	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

YP

Yeast Phenotype (YP)

	YP term	FDR (all)	SDYP (four levels)	Annotation (direct or inherited)
Yeast Phenotype (YP)	cellular processes	0	--	Direct
Yeast Phenotype (YP)	colony appearance	0.0004943	--	Direct
Yeast Phenotype (YP)	culture appearance	0.004271	--	Inherited
Yeast Phenotype (YP)	morphology	0.03851	Moderately Informative	Inherited
Yeast Phenotype (YP)	colony sectoring	0.000471	Highly Informative	Direct

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FP

Fly Phenotype (FP)

	FP term	FDR (all)	SDFP (four levels)	Annotation (direct or inherited)
Fly Phenotype (FP)	phenotype	0	--	Direct
Fly Phenotype (FP)	increased mortality	0	Least Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

FA

Fly Anatomy (FA)

	FA term	FDR (all)	SDFA (four levels)	Annotation (direct or inherited)
Fly Anatomy (FA)	somatic cell	0	--	Direct
Fly Anatomy (FA)	anatomical structure	1	--	Inherited
Fly Anatomy (FA)	material anatomical entity	1	--	Inherited
Fly Anatomy (FA)	cell	0	Least Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

ZA

Zebrafish Anatomy (ZA)

	ZA term	FDR (all)	SDZA (four levels)	Annotation (direct or inherited)
Zebrafish Anatomy (ZA)	whole organism	0	--	Direct
Zebrafish Anatomy (ZA)	anatomical system	0	--	Direct
Zebrafish Anatomy (ZA)	cavitated compound organ	0	--	Direct
Zebrafish Anatomy (ZA)	anatomical group	0	--	Direct
Zebrafish Anatomy (ZA)	anatomical structure	1	--	Inherited
Zebrafish Anatomy (ZA)	nervous system	0	Least Informative	Direct
Zebrafish Anatomy (ZA)	compound organ	0	Least Informative	Direct
Zebrafish Anatomy (ZA)	organism subdivision	0	Least Informative	Direct
Zebrafish Anatomy (ZA)	multi-tissue structure	0	Least Informative	Direct
Zebrafish Anatomy (ZA)	cardiovascular system	0	Moderately Informative	Direct
Zebrafish Anatomy (ZA)	head	0	Moderately Informative	Direct
Zebrafish Anatomy (ZA)	trunk	0	Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

XA

Xenopus Anatomy (XA)

	XA term	FDR (all)	SDXA (four levels)	Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)	genital system	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical structure	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical group	0	--	Direct
Xenopus ANatomical entity (XAN)	organism subdivision	0	--	Direct
Xenopus ANatomical entity (XAN)	compound organ	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical region	0	--	Direct
Xenopus ANatomical entity (XAN)	multicellular anatomical structure	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical system	1	--	Inherited
Xenopus ANatomical entity (XAN)	whole organism	1	--	Inherited
Xenopus ANatomical entity (XAN)	urogenital system	0	Least Informative	Direct

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AP

Arabidopsis Plant Ontology (AP)

	AP term	FDR (all)	SDAP (four levels)	Annotation (direct or inherited)
Plant ANatomical entity (PAN)	stomatal complex	0	--	Direct
Plant ANatomical entity (PAN)	epidermal cell	0	--	Direct
Plant ANatomical entity (PAN)	epidermis	0	--	Direct
Plant ANatomical entity (PAN)	shoot epidermis	0	--	Direct
Plant ANatomical entity (PAN)	plant cell	0	--	Direct
Plant ANatomical entity (PAN)	shoot system	0	--	Direct
Plant ANatomical entity (PAN)	portion of plant tissue	0	--	Direct
Plant ANatomical entity (PAN)	shoot epidermal cell	0	--	Direct
Plant ANatomical entity (PAN)	collective plant structure	0	--	Direct
Plant ANatomical entity (PAN)	plant structure	1	--	Inherited
Plant ANatomical entity (PAN)	collective plant organ structure	1	--	Inherited
Plant ANatomical entity (PAN)	guard cell	0	Least Informative	Direct

	AP term	FDR (all)	SDAP (four levels)	Annotation (direct or inherited)
Plant structure DEvelopment stage (PDE)	sporophyte vegetative stage	0.507	--	Inherited
Plant structure DEvelopment stage (PDE)	whole plant development stage	0.5098	--	Inherited
Plant structure DEvelopment stage (PDE)	life of whole plant stage	1	--	Inherited
Plant structure DEvelopment stage (PDE)	sporophyte development stage	1	--	Inherited
Plant structure DEvelopment stage (PDE)	0 seed germination stage	0.0000006417	Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

EC

Enzyme Commission (EC)

	EC term	FDR (all)	SDEC (four levels)	Annotation (direct or inherited)
Enzyme Commission (EC)	Ligases forming aminoacyl-tRNA and related compounds	0	--	Direct
Enzyme Commission (EC)	Proline--tRNA ligase	0	--	Direct
Enzyme Commission (EC)	Histidine--tRNA ligase	0	--	Direct
Enzyme Commission (EC)	Threonine--tRNA ligase	0	--	Direct
Enzyme Commission (EC)	Ligases	0	Moderately Informative	Direct
Enzyme Commission (EC)	Forming carbon-oxygen bonds	0	Informative	Direct

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CD

CTD Diseases (CD)

	CD term	FDR (all)	SDCD (four levels)	Annotation (direct or inherited)
CTD Diseases (CD)	Nervous System Diseases	0.02474	Least Informative	Inherited
CTD Diseases (CD)	Neuromuscular Diseases	0.0001019	Moderately Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

CC

CTD Chemicals (CC)

	CC term	FDR (all)	SDCC (four levels)	Annotation (direct or inherited)
CTD Chemicals (CC)	Carboxylic Acids	0	--	Direct
CTD Chemicals (CC)	Inorganic Chemicals	0	--	Direct
CTD Chemicals (CC)	Organic Chemicals	0	--	Direct
CTD Chemicals (CC)	Polycyclic Compounds	0	--	Direct
CTD Chemicals (CC)	Cidofovir	0.0003787	--	Direct
CTD Chemicals (CC)	Acetaldehyde	0.001921	--	Inherited
CTD Chemicals (CC)	Diphosphonates	0.09103	--	Inherited
CTD Chemicals (CC)	Heterocyclic Compounds	0.7489	--	Inherited
CTD Chemicals (CC)	Heterocyclic Compounds, 1-Ring	0.9471	--	Inherited
CTD Chemicals (CC)	Pyrimidines	0.4024	Least Informative	Inherited
CTD Chemicals (CC)	Organophosphorus Compounds	0.03953	Moderately Informative	Inherited
CTD Chemicals (CC)	Pyrimidinones	0.1162	Moderately Informative	Inherited
CTD Chemicals (CC)	Aldehydes	0.4794	Moderately Informative	Inherited
CTD Chemicals (CC)	Organophosphonates	0.5667	Informative	Inherited
CTD Chemicals (CC)	Clodronic Acid	0.0001939	Highly Informative	Direct
CTD Chemicals (CC)	chloroacetaldehyde	0.0005662	Highly Informative	Direct
CTD Chemicals (CC)	Cytosine	0.001754	Highly Informative	Inherited

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Distribution on sTOL

Plot distribution on species Tree Of Life (sTOL) for this domain, i.e., present or absent across genomes/tips

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Class II aaRS ABD-related superfamily