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Zn-dependent exopeptidases superfamily

Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Phosphorylase/hydrolase-like [ 53162] (8)
Superfamily:   Zn-dependent exopeptidases [ 53187] (9)
Families:   Pancreatic carboxypeptidases [ 53188] (4)
  Carboxypeptidase T [ 53198]
  Leucine aminopeptidase, C-terminal domain [ 53201]
  Bacterial dinuclear zinc exopeptidases [ 53204] (17)
  FolH catalytic domain-like [ 53210] (2)
  N-acetylmuramoyl-L-alanine amidase-like [ 102517] (2)
  AstE/AspA-like [ 142526] (2)
  Glutaminyl-peptide cyclotransferase-like [ 142532]
  FGase-like [ 159652] (2)

MP

Mouse Phenotype (MP)

MP term FDR (all) SDMP (four levels) Annotation (direct or inherited)
Mammalian Phenotype (MP)decreased prepulse inhibition0.0001254--Direct
Mammalian Phenotype (MP)abnormal prepulse inhibition0.0004976--Direct
Mammalian Phenotype (MP)abnormal synaptic transmission0.05678--Inherited
Mammalian Phenotype (MP)nervous system phenotype0.2599Least InformativeInherited
Mammalian Phenotype (MP)abnormal nervous system physiology0.4818Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal CNS synaptic transmission0.03937InformativeInherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

WP

Worm Phenotype (WP)

WP term FDR (all) SDWP (four levels) Annotation (direct or inherited)
Worm Phenotype (WP)lethal0--Direct
Worm Phenotype (WP)development variant0--Direct
Worm Phenotype (WP)organism development variant0--Direct
Worm Phenotype (WP)physiology variant1--Inherited
Worm Phenotype (WP)pericellular component development variant0Moderately InformativeDirect
Worm Phenotype (WP)basement membrane remodeling variant0InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

YP

Yeast Phenotype (YP)

YP term FDR (all) SDYP (four levels) Annotation (direct or inherited)
Yeast Phenotype (YP)cellular processes0--Direct
Yeast Phenotype (YP)stress resistance0--Direct
Yeast Phenotype (YP)resistance to chemicals0Least InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

FA

Fly Anatomy (FA)

FA term FDR (all) SDFA (four levels) Annotation (direct or inherited)
Fly Anatomy (FA)multicellular structure0--Direct
Fly Anatomy (FA)anatomical structure1--Inherited
Fly Anatomy (FA)material anatomical entity1--Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

ZA

Zebrafish Anatomy (ZA)

ZA term FDR (all) SDZA (four levels) Annotation (direct or inherited)
Zebrafish Anatomy (ZA)whole organism0--Direct
Zebrafish Anatomy (ZA)anatomical structure1--Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

XA

Xenopus Anatomy (XA)

XA term FDR (all) SDXA (four levels) Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)anatomical structure0--Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

AP

Arabidopsis Plant Ontology (AP)

AP term FDR (all) SDAP (four levels) Annotation (direct or inherited)
Plant ANatomical entity (PAN)plant cell0--Direct
Plant ANatomical entity (PAN)shoot system0--Direct
Plant ANatomical entity (PAN)collective plant structure0--Direct
Plant ANatomical entity (PAN)plant structure1--Inherited
Plant ANatomical entity (PAN)collective plant organ structure1--Inherited
 
AP term FDR (all) SDAP (four levels) Annotation (direct or inherited)
Plant structure DEvelopment stage (PDE)floral organ differentiation stage0--Direct
Plant structure DEvelopment stage (PDE)collective plant organ structure development stage0--Direct
Plant structure DEvelopment stage (PDE)plant organ development stage0--Direct
Plant structure DEvelopment stage (PDE)reproductive shoot system development stage0--Direct
Plant structure DEvelopment stage (PDE)collective phyllome structure development stage0--Direct
Plant structure DEvelopment stage (PDE)floral organ formation stage0--Direct
Plant structure DEvelopment stage (PDE)flower development stage1--Inherited
Plant structure DEvelopment stage (PDE)shoot system development stage1--Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

EC

Enzyme Commission (EC)

EC term FDR (all) SDEC (four levels) Annotation (direct or inherited)
Enzyme Commission (EC)Glutaminyl-peptide cyclotransferase0--Direct
Enzyme Commission (EC)Leucyl aminopeptidase0--Direct
Enzyme Commission (EC)Bacterial leucyl aminopeptidase0--Direct
Enzyme Commission (EC)Acetylornithine deacetylase0--Direct
Enzyme Commission (EC)Succinyl-diaminopimelate desuccinylase0--Direct
Enzyme Commission (EC)N-acetyldiaminopimelate deacetylase0--Direct
Enzyme Commission (EC)Succinylglutamate desuccinylase0--Direct
Enzyme Commission (EC)Aspartoacylase0.00000000000004992--Direct
Enzyme Commission (EC)Allantoate deiminase0.00000000000008437--Direct
Enzyme Commission (EC)Tripeptide aminopeptidase0.00000000005914--Direct
Enzyme Commission (EC)Cytosol nonspecific dipeptidase0.0000000008885--Direct
Enzyme Commission (EC)N-acyl-aliphatic-L-amino acid amidohydrolase0.00003238--Direct
Enzyme Commission (EC)Beta-Ala-His dipeptidase0.00003445--Direct
Enzyme Commission (EC)N-acyl-aromatic-L-amino acid amidohydrolase0.00003654--Direct
Enzyme Commission (EC)N-carbamoyl-L-amino-acid hydrolase0.0007948--Direct
Enzyme Commission (EC)PepB aminopeptidase0.0008344--Direct
Enzyme Commission (EC)Transferases1--Inherited
Enzyme Commission (EC)Acyltransferases1--Inherited
Enzyme Commission (EC)Hydrolases0Least InformativeDirect
Enzyme Commission (EC)Acting on peptide bonds (peptidases)0Moderately InformativeDirect
Enzyme Commission (EC)Acting on carbon-nitrogen bonds, other than peptide bonds0Moderately InformativeDirect
Enzyme Commission (EC)Aminoacyltransferases0.8614Moderately InformativeInherited
Enzyme Commission (EC)In linear amides0InformativeDirect
Enzyme Commission (EC)Aminopeptidases0Highly InformativeDirect
Enzyme Commission (EC)Metallocarboxypeptidases0Highly InformativeDirect
Enzyme Commission (EC)Dipeptidases1Highly InformativeInherited
Enzyme Commission (EC)In linear amidines1Highly InformativeInherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

KW

UniProtKB KeyWords (KW)

KW term FDR (all) SDKW (four levels) Annotation (direct or inherited)
Molecular functionHydrolase0Least InformativeDirect

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CC

CTD Chemicals (CC)

CC term FDR (all) SDCC (four levels) Annotation (direct or inherited)
CTD Chemicals (CC)Organic Chemicals0--Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

Distribution on sTOL

Plot distribution on species Tree Of Life (sTOL) for this domain, i.e., present or absent across genomes/tips
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