Ubiquitin-like superfamily

DO

Disease Ontology (DO)

	DO term	FDR (all)	SDDO (four levels)	Annotation (direct or inherited)
Disease Ontology (DO)	pilocytic astrocytoma	0.0004511	--	Direct
Disease Ontology (DO)	disease of cellular proliferation	0.009963	--	Inherited
Disease Ontology (DO)	astrocytoma	0.3051	--	Inherited
Disease Ontology (DO)	cancer	0.8504	--	Inherited
Disease Ontology (DO)	cell type cancer	0.5555	Moderately Informative	Inherited
Disease Ontology (DO)	malignant glioma	0.5741	Informative	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

HP

Human Phenotype (HP)

	HP term	FDR (all)	SDHP (four levels)	Annotation (direct or inherited)
Mode of Inheritance (MI)	Somatic mutation	0.0004828	Informative	Direct

	HP term	FDR (all)	SDHP (four levels)	Annotation (direct or inherited)
Phenotypic Abnormality (PA)	Oligodontia	0.00005251	--	Direct
Phenotypic Abnormality (PA)	Alveolar cell carcinoma	0.0006111	--	Direct
Phenotypic Abnormality (PA)	Neoplasm of the tracheobronchial system	0.003198	--	Inherited
Phenotypic Abnormality (PA)	Neoplasm of the lung	0.02	--	Inherited
Phenotypic Abnormality (PA)	Neoplasm of the respiratory system	0.02179	--	Inherited
Phenotypic Abnormality (PA)	Reduced number of teeth	0.08864	--	Inherited
Phenotypic Abnormality (PA)	Abnormal respiratory system morphology	0.183	--	Inherited
Phenotypic Abnormality (PA)	Abnormal number of teeth	0.1944	--	Inherited
Phenotypic Abnormality (PA)	Abnormality of the mouth	0.3191	--	Inherited
Phenotypic Abnormality (PA)	Abnormality of head or neck	0.4513	--	Inherited
Phenotypic Abnormality (PA)	Abnormal oral morphology	0.483	--	Inherited
Phenotypic Abnormality (PA)	Abnormality of the face	0.5293	--	Inherited
Phenotypic Abnormality (PA)	Neoplasm by anatomical site	0.7179	--	Inherited
Phenotypic Abnormality (PA)	Abnormality of the head	0.4308	Least Informative	Inherited
Phenotypic Abnormality (PA)	Neoplasm	0.1412	Moderately Informative	Inherited
Phenotypic Abnormality (PA)	Abnormality of the respiratory system	0.3727	Moderately Informative	Inherited
Phenotypic Abnormality (PA)	Abnormal oral cavity morphology	1	Moderately Informative	Inherited
Phenotypic Abnormality (PA)	Abnormality of the upper respiratory tract	0.2448	Informative	Inherited
Phenotypic Abnormality (PA)	Abnormality of the dentition	0.3721	Informative	Inherited
Phenotypic Abnormality (PA)	Abnormal lung morphology	0.5888	Informative	Inherited
Phenotypic Abnormality (PA)	Abnormal tracheobronchial morphology	0.2198	Highly Informative	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

MP

Mouse Phenotype (MP)

	MP term	FDR (all)	SDMP (four levels)	Annotation (direct or inherited)
Mammalian Phenotype (MP)	abnormal amniotic cavity morphology	0.000692	--	Direct
Mammalian Phenotype (MP)	abnormal tumor incidence	0.3726	--	Inherited
Mammalian Phenotype (MP)	altered tumor susceptibility	0.3914	--	Inherited
Mammalian Phenotype (MP)	increased classified tumor incidence	0.4581	--	Inherited
Mammalian Phenotype (MP)	abnormal classified tumor incidence	0.6933	--	Inherited
Mammalian Phenotype (MP)	increased tumor incidence	0.9901	--	Inherited
Mammalian Phenotype (MP)	embryo phenotype	0.2532	Moderately Informative	Inherited
Mammalian Phenotype (MP)	neoplasm	0.5116	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal extraembryonic tissue morphology	0.0224	Informative	Inherited
Mammalian Phenotype (MP)	increased hamartoma incidence	0.000801	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

WP

Worm Phenotype (WP)

	WP term	FDR (all)	SDWP (four levels)	Annotation (direct or inherited)
Worm Phenotype (WP)	lethal	0	--	Direct
Worm Phenotype (WP)	development variant	0	--	Direct
Worm Phenotype (WP)	organism development variant	0	--	Direct
Worm Phenotype (WP)	protein aggregation variant	0.0000001265	--	Direct
Worm Phenotype (WP)	protein protein interaction variant	0.0000001955	--	Direct
Worm Phenotype (WP)	muscle system physiology variant	0.0000006786	--	Direct
Worm Phenotype (WP)	body behavior variant	0.0000006962	--	Direct
Worm Phenotype (WP)	organism segment behavior variant	0.00000142	--	Direct
Worm Phenotype (WP)	organism region behavior variant	0.000002923	--	Direct
Worm Phenotype (WP)	heteroplasmy	0.00001564	--	Direct
Worm Phenotype (WP)	fewer seam cells	0.00007312	--	Direct
Worm Phenotype (WP)	muscle dystrophy	0.001822	--	Inherited
Worm Phenotype (WP)	cell number variant	0.01584	--	Inherited
Worm Phenotype (WP)	organ system development variant	0.1081	--	Inherited
Worm Phenotype (WP)	organ system physiology variant	0.3619	--	Inherited
Worm Phenotype (WP)	behavior variant	0.3896	--	Inherited
Worm Phenotype (WP)	embryonic development variant	0.3974	--	Inherited
Worm Phenotype (WP)	organism physiology variant	0.4027	--	Inherited
Worm Phenotype (WP)	morphology variant	0.45	--	Inherited
Worm Phenotype (WP)	organism homeostasis metabolism variant	0.8489	--	Inherited
Worm Phenotype (WP)	physiology variant	1	--	Inherited
Worm Phenotype (WP)	cell morphology variant	0.0003729	Least Informative	Direct
Worm Phenotype (WP)	organism metabolism processing variant	0.001275	Least Informative	Inherited
Worm Phenotype (WP)	cell physiology variant	0.006513	Least Informative	Inherited
Worm Phenotype (WP)	cell development variant	0.01635	Least Informative	Inherited
Worm Phenotype (WP)	organism behavior variant	0.3739	Least Informative	Inherited
Worm Phenotype (WP)	protein interaction variant	0.00004565	Moderately Informative	Direct
Worm Phenotype (WP)	muscle cell physiology variant	0.0002359	Informative	Direct
Worm Phenotype (WP)	epithelial system development variant	0.1823	Informative	Inherited
Worm Phenotype (WP)	body muscle dystrophy	0.0000001518	Highly Informative	Direct
Worm Phenotype (WP)	gastrulation variant	0.000139	Highly Informative	Direct
Worm Phenotype (WP)	cell polarity variant	0.0005498	Highly Informative	Direct
Worm Phenotype (WP)	epithelial development variant	0.006089	Highly Informative	Inherited
Worm Phenotype (WP)	cell number decreased	0.2244	Highly Informative	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

YP

Yeast Phenotype (YP)

	YP term	FDR (all)	SDYP (four levels)	Annotation (direct or inherited)
Yeast Phenotype (YP)	competitive fitness	0	--	Direct
Yeast Phenotype (YP)	fitness	0	--	Direct
Yeast Phenotype (YP)	sporulation	0.0003679	--	Direct
Yeast Phenotype (YP)	development	0.02225	--	Inherited
Yeast Phenotype (YP)	metabolism and growth	0.1854	Least Informative	Inherited
Yeast Phenotype (YP)	protein/peptide accumulation	0.0001303	Highly Informative	Direct
Yeast Phenotype (YP)	sexual cycle	0.02105	Highly Informative	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

ZA

Zebrafish Anatomy (ZA)

	ZA term	FDR (all)	SDZA (four levels)	Annotation (direct or inherited)
Zebrafish Anatomy (ZA)	whole organism	0	--	Direct
Zebrafish Anatomy (ZA)	anatomical structure	1	--	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

XA

Xenopus Anatomy (XA)

	XA term	FDR (all)	SDXA (four levels)	Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)	anatomical structure	0	--	Direct
Xenopus ANatomical entity (XAN)	central nervous system	0.0001991	--	Direct
Xenopus ANatomical entity (XAN)	head region	0.00085	--	Direct
Xenopus ANatomical entity (XAN)	multicellular anatomical structure	0.02109	--	Inherited
Xenopus ANatomical entity (XAN)	anatomical group	0.07279	--	Inherited
Xenopus ANatomical entity (XAN)	anatomical region	0.1093	--	Inherited
Xenopus ANatomical entity (XAN)	compound organ	0.3164	--	Inherited
Xenopus ANatomical entity (XAN)	organism subdivision	0.6386	--	Inherited
Xenopus ANatomical entity (XAN)	anatomical system	1	--	Inherited
Xenopus ANatomical entity (XAN)	whole organism	1	--	Inherited
Xenopus ANatomical entity (XAN)	head	0.0009265	Least Informative	Direct
Xenopus ANatomical entity (XAN)	nervous system	0.00166	Least Informative	Inherited
Xenopus ANatomical entity (XAN)	cavitated compound organ	0.2455	Least Informative	Inherited
Xenopus ANatomical entity (XAN)	brain	0.0002655	Moderately Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

AP

Arabidopsis Plant Ontology (AP)

	AP term	FDR (all)	SDAP (four levels)	Annotation (direct or inherited)
Plant ANatomical entity (PAN)	plant cell	0.6529	--	Inherited
Plant ANatomical entity (PAN)	plant structure	1	--	Inherited
Plant ANatomical entity (PAN)	pollen tube cell	0.0000007609	Informative	Direct
Plant ANatomical entity (PAN)	gamete	0.0005298	Informative	Direct

	AP term	FDR (all)	SDAP (four levels)	Annotation (direct or inherited)
Plant structure DEvelopment stage (PDE)	androecium development stage	0.000008512	--	Direct
Plant structure DEvelopment stage (PDE)	floral organ differentiation stage	0.09055	--	Inherited
Plant structure DEvelopment stage (PDE)	plant organ development stage	0.1343	--	Inherited
Plant structure DEvelopment stage (PDE)	collective phyllome structure development stage	0.1397	--	Inherited
Plant structure DEvelopment stage (PDE)	floral organ formation stage	0.1798	--	Inherited
Plant structure DEvelopment stage (PDE)	reproductive shoot system development stage	0.1866	--	Inherited
Plant structure DEvelopment stage (PDE)	collective plant organ structure development stage	0.2377	--	Inherited
Plant structure DEvelopment stage (PDE)	flower development stage	1	--	Inherited
Plant structure DEvelopment stage (PDE)	shoot system development stage	1	--	Inherited
Plant structure DEvelopment stage (PDE)	pollen development stage	0.000003323	Moderately Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

EC

Enzyme Commission (EC)

	EC term	FDR (all)	SDEC (four levels)	Annotation (direct or inherited)
Enzyme Commission (EC)	Phosphatidylinositol-4,5-bisphosphate 3-kinase	0	--	Direct
Enzyme Commission (EC)	Phosphatidylinositol-4-phosphate 3-kinase	0	--	Direct
Enzyme Commission (EC)	Ubiquitinyl hydrolase 1	0	--	Direct
Enzyme Commission (EC)	Very-long-chain enoyl-CoA reductase	0.00000000000003439	--	Direct
Enzyme Commission (EC)	1-phosphatidylinositol 4-kinase	0.00000000009506	--	Direct
Enzyme Commission (EC)	Phosphatidylinositol 3-kinase	0.000000002038	--	Direct
Enzyme Commission (EC)	RBR-type E3 ubiquitin transferase	0.00000003747	--	Direct
Enzyme Commission (EC)	Transferases	0.000002716	--	Direct
Enzyme Commission (EC)	Acyltransferases	0.0001528	--	Direct
Enzyme Commission (EC)	Acting on the CH-CH group of donors	0.005616	--	Inherited
Enzyme Commission (EC)	Acting on ester bonds	0.06331	--	Inherited
Enzyme Commission (EC)	Transferring phosphorus-containing groups	0.0000000001648	Least Informative	Direct
Enzyme Commission (EC)	Hydrolases	0.0000000008392	Least Informative	Direct
Enzyme Commission (EC)	Oxidoreductases	1	Least Informative	Inherited
Enzyme Commission (EC)	Aminoacyltransferases	0	Moderately Informative	Direct
Enzyme Commission (EC)	Acting on peptide bonds (peptidases)	2.574e-16	Moderately Informative	Direct
Enzyme Commission (EC)	Protein-serine/threonine kinases	0.0000000002786	Moderately Informative	Direct
Enzyme Commission (EC)	Phosphoric monoester hydrolases	0.000000002276	Moderately Informative	Direct
Enzyme Commission (EC)	Phosphotransferases with an alcohol group as acceptor	0.0000004051	Moderately Informative	Direct
Enzyme Commission (EC)	Omega peptidases	0	Informative	Direct
Enzyme Commission (EC)	Protein-tyrosine-phosphatase	0.000001851	Informative	Direct
Enzyme Commission (EC)	Protein-tyrosine kinases	0.000008754	Informative	Direct
Enzyme Commission (EC)	With NAD(+) or NADP(+) as acceptor	0.00005231	Informative	Direct
Enzyme Commission (EC)	Phosphoric diester hydrolases	0.003827	Informative	Inherited
Enzyme Commission (EC)	Non-specific protein-tyrosine kinase	0.000000000001552	Highly Informative	Direct
Enzyme Commission (EC)	Phosphoinositide phospholipase C	0.00000001195	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

CC

CTD Chemicals (CC)

	CC term	FDR (all)	SDCC (four levels)	Annotation (direct or inherited)
CTD Chemicals (CC)	Niclosamide	0.0001384	--	Direct
CTD Chemicals (CC)	Salicylamides	0.0004593	--	Direct
CTD Chemicals (CC)	Onium Compounds	0.0009716	--	Direct
CTD Chemicals (CC)	Polycyclic Compounds	0.007737	--	Inherited
CTD Chemicals (CC)	Pyrenes	0.01468	--	Inherited
CTD Chemicals (CC)	Heterocyclic Compounds	0.04324	--	Inherited
CTD Chemicals (CC)	Alkylmercury Compounds	0.09671	--	Inherited
CTD Chemicals (CC)	Organic Chemicals	0.1769	--	Inherited
CTD Chemicals (CC)	Hydrocarbons	0.1976	--	Inherited
CTD Chemicals (CC)	Inorganic Chemicals	0.2112	--	Inherited
CTD Chemicals (CC)	Heterocyclic Compounds, 2-Ring	0.3142	--	Inherited
CTD Chemicals (CC)	Heterocyclic Compounds, Bridged-Ring	0.3477	--	Inherited
CTD Chemicals (CC)	Hydrocarbons, Cyclic	0.4396	--	Inherited
CTD Chemicals (CC)	Heterocyclic Compounds, 1-Ring	0.548	--	Inherited
CTD Chemicals (CC)	Hydrocarbons, Aromatic	0.6071	--	Inherited
CTD Chemicals (CC)	Heterocyclic Compounds, Fused-Ring	0.7627	--	Inherited
CTD Chemicals (CC)	Aniline Compounds	1	--	Inherited
CTD Chemicals (CC)	Methylmercury Compounds	1	--	Inherited
CTD Chemicals (CC)	Sulfones	1	--	Inherited
CTD Chemicals (CC)	Amines	0.0001785	Least Informative	Direct
CTD Chemicals (CC)	Polycyclic Aromatic Hydrocarbons	0.1316	Least Informative	Inherited
CTD Chemicals (CC)	Sulfur Compounds	0.2599	Least Informative	Inherited
CTD Chemicals (CC)	Amides	0.4356	Least Informative	Inherited
CTD Chemicals (CC)	Pyrimidines	0.5666	Least Informative	Inherited
CTD Chemicals (CC)	Azoles	0.705	Least Informative	Inherited
CTD Chemicals (CC)	Benzopyrenes	0.0006906	Moderately Informative	Direct
CTD Chemicals (CC)	Organometallic Compounds	0.05527	Moderately Informative	Inherited
CTD Chemicals (CC)	Anilides	0.09967	Moderately Informative	Inherited
CTD Chemicals (CC)	Thiazoles	0.7352	Moderately Informative	Inherited
CTD Chemicals (CC)	Sulfonamides	1	Moderately Informative	Inherited
CTD Chemicals (CC)	Salicylanilides	0.0004779	Informative	Direct
CTD Chemicals (CC)	Benzothiazoles	0.004994	Informative	Inherited
CTD Chemicals (CC)	Triazines	0.4627	Informative	Inherited
CTD Chemicals (CC)	Bridged Bicyclo Compounds, Heterocyclic	0.9788	Informative	Inherited
CTD Chemicals (CC)	Organomercury Compounds	1	Informative	Inherited
CTD Chemicals (CC)	N-(6-(6-chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)benzo(d)thiazol-2-yl)acetamide	0.00000118	Highly Informative	Direct
CTD Chemicals (CC)	ZSTK474	0.000004713	Highly Informative	Direct
CTD Chemicals (CC)	1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1	0.00005804	Highly Informative	Direct
CTD Chemicals (CC)	methylmercury II	0.0008307	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

Distribution on sTOL

Plot distribution on species Tree Of Life (sTOL) for this domain, i.e., present or absent across genomes/tips

Plot tree as:

Download Newick format tree:

Browsing in TREE OF LIFE:

(show help)

LINKOUT

Ubiquitin-like superfamily