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Thioesterase/thiol ester dehydrase-isomerase superfamily

Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Thioesterase/thiol ester dehydrase-isomerase [ 54636]
Superfamily:   Thioesterase/thiol ester dehydrase-isomerase [ 54637] (8)
Families:   4HBT-like [ 54638] (18)
  beta-Hydroxydecanol thiol ester dehydrase [ 54641]
  Acyl-CoA thioesterase [ 54644] (2)
  MaoC-like [ 82636] (6)
  PaaI/YdiI-like [ 89902] (14)
  FabZ-like [ 110902]
  TTHA0967-like [ 143187] (2)
  Acyl-ACP thioesterase-like [ 143190] (2)

MP

Mouse Phenotype (MP)

MP term FDR (all) SDMP (four levels) Annotation (direct or inherited)
Mammalian Phenotype (MP)abnormal liver morphology0--Direct
Mammalian Phenotype (MP)abnormal hepatobiliary system morphology0--Direct
Mammalian Phenotype (MP)abnormal lipid level0.00008286--Direct
Mammalian Phenotype (MP)homeostasis/metabolism phenotype0.06593--Inherited
Mammalian Phenotype (MP)abnormal homeostasis0.0391Least InformativeInherited
Mammalian Phenotype (MP)liver/biliary system phenotype0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal lipid homeostasis0.0001129Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal fatty acid level0.00000004197Highly InformativeDirect

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WP

Worm Phenotype (WP)

WP term FDR (all) SDWP (four levels) Annotation (direct or inherited)
Worm Phenotype (WP)postembryonic development variant0--Direct
Worm Phenotype (WP)embryonic lethal0--Direct
Worm Phenotype (WP)lethal0--Direct
Worm Phenotype (WP)fertility variant0--Direct
Worm Phenotype (WP)development variant0--Direct
Worm Phenotype (WP)morphology variant0--Direct
Worm Phenotype (WP)organism development variant0--Direct
Worm Phenotype (WP)organism morphology variant0--Direct
Worm Phenotype (WP)organ system physiology variant0--Direct
Worm Phenotype (WP)reproductive system physiology variant0--Direct
Worm Phenotype (WP)maternal sterile0--Direct
Worm Phenotype (WP)hermaphrodite sterile0--Direct
Worm Phenotype (WP)embryonic development variant0--Direct
Worm Phenotype (WP)hermaphrodite fertility variant0--Direct
Worm Phenotype (WP)hermaphrodite fertility reduced0--Direct
Worm Phenotype (WP)fertility reduced0--Direct
Worm Phenotype (WP)physiology variant1--Inherited
Worm Phenotype (WP)sterile1--Inherited

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YP

Yeast Phenotype (YP)

YP term FDR (all) SDYP (four levels) Annotation (direct or inherited)
Yeast Phenotype (YP)competitive fitness0--Direct
Yeast Phenotype (YP)fitness0--Direct

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XA

Xenopus Anatomy (XA)

XA term FDR (all) SDXA (four levels) Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)head region0--Direct
Xenopus ANatomical entity (XAN)trunk region0--Direct
Xenopus ANatomical entity (XAN)genital system0--Direct
Xenopus ANatomical entity (XAN)central nervous system0--Direct
Xenopus ANatomical entity (XAN)anatomical structure0--Direct
Xenopus ANatomical entity (XAN)anatomical group0--Direct
Xenopus ANatomical entity (XAN)organism subdivision0--Direct
Xenopus ANatomical entity (XAN)compound organ0--Direct
Xenopus ANatomical entity (XAN)anatomical region0--Direct
Xenopus ANatomical entity (XAN)multicellular anatomical structure0--Direct
Xenopus ANatomical entity (XAN)anatomical system1--Inherited
Xenopus ANatomical entity (XAN)whole organism1--Inherited
Xenopus ANatomical entity (XAN)urogenital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)nervous system0Least InformativeDirect
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)trunk0Least InformativeDirect
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect
 
XA term FDR (all) SDXA (four levels) Annotation (direct or inherited)
Xenopus DEvelopment stage (XDE)NF stage0--Direct

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AP

Arabidopsis Plant Ontology (AP)

AP term FDR (all) SDAP (four levels) Annotation (direct or inherited)
Plant ANatomical entity (PAN)shoot system0--Direct
Plant ANatomical entity (PAN)portion of plant tissue0--Direct
Plant ANatomical entity (PAN)collective plant structure0--Direct
Plant ANatomical entity (PAN)plant structure1--Inherited
Plant ANatomical entity (PAN)collective plant organ structure1--Inherited
 
AP term FDR (all) SDAP (four levels) Annotation (direct or inherited)
Plant structure DEvelopment stage (PDE)whole plant development stage0--Direct
Plant structure DEvelopment stage (PDE)sporophyte vegetative stage0--Direct
Plant structure DEvelopment stage (PDE)floral organ differentiation stage0--Direct
Plant structure DEvelopment stage (PDE)corolla development stage0--Direct
Plant structure DEvelopment stage (PDE)flowering stage0--Direct
Plant structure DEvelopment stage (PDE)plant embryo stage0--Direct
Plant structure DEvelopment stage (PDE)collective plant organ structure development stage0--Direct
Plant structure DEvelopment stage (PDE)plant organ development stage0--Direct
Plant structure DEvelopment stage (PDE)reproductive shoot system development stage0--Direct
Plant structure DEvelopment stage (PDE)collective phyllome structure development stage0--Direct
Plant structure DEvelopment stage (PDE)floral organ formation stage0--Direct
Plant structure DEvelopment stage (PDE)flower development stage1--Inherited
Plant structure DEvelopment stage (PDE)life of whole plant stage1--Inherited
Plant structure DEvelopment stage (PDE)shoot system development stage1--Inherited
Plant structure DEvelopment stage (PDE)sporophyte development stage1--Inherited

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EC

Enzyme Commission (EC)

EC term FDR (all) SDEC (four levels) Annotation (direct or inherited)
Enzyme Commission (EC)(3R)-hydroxyacyl-CoA dehydrogenase0--Direct
Enzyme Commission (EC)1,4-dihydroxy-2-naphthoyl-CoA hydrolase0--Direct
Enzyme Commission (EC)Hydro-lyases0--Direct
Enzyme Commission (EC)3-hydroxyacyl-[acyl-carrier-protein] dehydratase0--Direct
Enzyme Commission (EC)Trans-2-decenoyl-[acyl-carrier-protein] isomerase0--Direct
Enzyme Commission (EC)Enoyl-[acyl-carrier-protein] reductase (NADH)0.0000000000002639--Direct
Enzyme Commission (EC)Enoyl-CoA hydratase 20.0000000003981--Direct
Enzyme Commission (EC)Carnitine 3-dehydrogenase0.000000009221--Direct
Enzyme Commission (EC)Acting on ester bonds0.0000006046--Direct
Enzyme Commission (EC)Palmitoyl-CoA hydrolase0.00002329--Direct
Enzyme Commission (EC)hydratase0.0001816--Direct
Enzyme Commission (EC)2-methylfumaryl-CoA hydratase0.0001816--Direct
Enzyme Commission (EC)3-hydroxybutyryl-CoA dehydratase0.0001816--Direct
Enzyme Commission (EC)Acting on the CH-CH group of donors0.4306--Inherited
Enzyme Commission (EC)Transferases1--Inherited
Enzyme Commission (EC)Acyltransferases1--Inherited
Enzyme Commission (EC)Lyases0Least InformativeDirect
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Carbon-oxygen lyases0Moderately InformativeDirect
Enzyme Commission (EC)Isomerases0Moderately InformativeDirect
Enzyme Commission (EC)Acting on the CH-OH group of donors1Moderately InformativeInherited
Enzyme Commission (EC)Transferring groups other than amino-acyl groups1Moderately InformativeInherited
Enzyme Commission (EC)Thiolester hydrolases0InformativeDirect
Enzyme Commission (EC)Intramolecular oxidoreductases0InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0.011InformativeInherited
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor1InformativeInherited
Enzyme Commission (EC)[Acyl-carrier-protein] S-acetyltransferase0Highly InformativeDirect
Enzyme Commission (EC)Transposing C=C bonds0Highly InformativeDirect
Enzyme Commission (EC)Fatty-acyl-CoA synthase system0.00000000000001461Highly InformativeDirect
Enzyme Commission (EC)[Acyl-carrier-protein] S-malonyltransferase0.00000000000003901Highly InformativeDirect
Enzyme Commission (EC)Oleoyl-[acyl-carrier-protein] hydrolase0.0001382Highly InformativeDirect

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KW

UniProtKB KeyWords (KW)

KW term FDR (all) SDKW (four levels) Annotation (direct or inherited)
Molecular functionHydrolase0.000000001864Least InformativeDirect

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CD

CTD Diseases (CD)

CD term FDR (all) SDCD (four levels) Annotation (direct or inherited)
CTD Diseases (CD)Digestive System Diseases0Least InformativeDirect
CTD Diseases (CD)Liver Diseases0Moderately InformativeDirect

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CC

CTD Chemicals (CC)

CC term FDR (all) SDCC (four levels) Annotation (direct or inherited)
CTD Chemicals (CC)Heterocyclic Compounds0--Direct
CTD Chemicals (CC)Heterocyclic Compounds, 1-Ring0--Direct
CTD Chemicals (CC)Hydrocarbons0--Direct
CTD Chemicals (CC)Hydrocarbons, Aromatic0--Direct
CTD Chemicals (CC)Hydrocarbons, Cyclic0--Direct
CTD Chemicals (CC)Inorganic Chemicals0--Direct
CTD Chemicals (CC)Organic Chemicals0--Direct
CTD Chemicals (CC)Polycyclic Compounds0--Direct
CTD Chemicals (CC)Oleic Acid0.00006316--Direct
CTD Chemicals (CC)GW 40640.0001026--Direct
CTD Chemicals (CC)Oleic Acids0.0001076--Direct
CTD Chemicals (CC)Hydrocarbons, Fluorinated0.01713--Inherited
CTD Chemicals (CC)Lipids0.2942--Inherited
CTD Chemicals (CC)Fatty Acids0.8718--Inherited
CTD Chemicals (CC)Azoles0Least InformativeDirect
CTD Chemicals (CC)Sulfur Compounds0.09399Least InformativeInherited
CTD Chemicals (CC)Amines0.5995Least InformativeInherited
CTD Chemicals (CC)Fatty Acids, Unsaturated0.01776Moderately InformativeInherited
CTD Chemicals (CC)Hydrocarbons, Halogenated0.03613Moderately InformativeInherited
CTD Chemicals (CC)Thiazoles0.1707Moderately InformativeInherited
CTD Chemicals (CC)Hydroxylamines0.4676Moderately InformativeInherited
CTD Chemicals (CC)Oximes0.0000583InformativeDirect
CTD Chemicals (CC)Fatty Acids, Monounsaturated0.0007951InformativeDirect
CTD Chemicals (CC)Fluorocarbons0.0008147InformativeDirect
CTD Chemicals (CC)Isoxazoles0.05688InformativeInherited
CTD Chemicals (CC)6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime0.000001426Highly InformativeDirect

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Distribution on sTOL

Plot distribution on species Tree Of Life (sTOL) for this domain, i.e., present or absent across genomes/tips
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