L30e-like superfamily

MP

Mouse Phenotype (MP)

	MP term	FDR (all)	SDMP (four levels)	Annotation (direct or inherited)
Mammalian Phenotype (MP)	increased anti-histone antibody level	0.00000004029	--	Direct
Mammalian Phenotype (MP)	increased anti-double stranded DNA antibody level	0.00003239	--	Direct
Mammalian Phenotype (MP)	increased IgG1 level	0.00004865	--	Direct
Mammalian Phenotype (MP)	glomerulonephritis	0.00007461	--	Direct
Mammalian Phenotype (MP)	increased IgM level	0.0001244	--	Direct
Mammalian Phenotype (MP)	increased autoantibody level	0.0002026	--	Direct
Mammalian Phenotype (MP)	increased hematopoietic cell number	0.0002249	--	Direct
Mammalian Phenotype (MP)	cortical renal glomerulopathies	0.0003686	--	Direct
Mammalian Phenotype (MP)	kidney inflammation	0.0004057	--	Direct
Mammalian Phenotype (MP)	abnormal IgM level	0.0008076	--	Direct
Mammalian Phenotype (MP)	abnormal leukocyte cell number	0.001251	--	Inherited
Mammalian Phenotype (MP)	increased immunoglobulin level	0.001728	--	Inherited
Mammalian Phenotype (MP)	abnormal renal glomerulus morphology	0.001968	--	Inherited
Mammalian Phenotype (MP)	abnormal leukocyte morphology	0.002305	--	Inherited
Mammalian Phenotype (MP)	abnormal immune system cell morphology	0.002416	--	Inherited
Mammalian Phenotype (MP)	abnormal kidney cortex morphology	0.003128	--	Inherited
Mammalian Phenotype (MP)	abnormal self tolerance	0.00408	--	Inherited
Mammalian Phenotype (MP)	abnormal immune tolerance	0.004355	--	Inherited
Mammalian Phenotype (MP)	abnormal IgG level	0.004566	--	Inherited
Mammalian Phenotype (MP)	abnormal nephron morphology	0.006112	--	Inherited
Mammalian Phenotype (MP)	abnormal immune system morphology	0.006565	--	Inherited
Mammalian Phenotype (MP)	abnormal immunoglobulin level	0.008607	--	Inherited
Mammalian Phenotype (MP)	abnormal hematopoietic cell morphology	0.008835	--	Inherited
Mammalian Phenotype (MP)	abnormal hematopoietic system morphology/development	0.01527	--	Inherited
Mammalian Phenotype (MP)	abnormal B cell physiology	0.01536	--	Inherited
Mammalian Phenotype (MP)	abnormal kidney morphology	0.027	--	Inherited
Mammalian Phenotype (MP)	abnormal lymphocyte physiology	0.05239	--	Inherited
Mammalian Phenotype (MP)	increased inflammatory response	0.05404	--	Inherited
Mammalian Phenotype (MP)	renal/urinary system phenotype	0.06225	--	Inherited
Mammalian Phenotype (MP)	abnormal immune cell physiology	0.11	--	Inherited
Mammalian Phenotype (MP)	abnormal cell-mediated immunity	0.1117	--	Inherited
Mammalian Phenotype (MP)	abnormal adaptive immunity	0.1156	--	Inherited
Mammalian Phenotype (MP)	abnormal blood cell physiology	0.1258	--	Inherited
Mammalian Phenotype (MP)	abnormal hematopoietic system physiology	0.5619	--	Inherited
Mammalian Phenotype (MP)	abnormal immune system physiology	0.8691	--	Inherited
Mammalian Phenotype (MP)	hematopoietic system phenotype	0.02813	Least Informative	Inherited
Mammalian Phenotype (MP)	immune system phenotype	0.0303	Least Informative	Inherited
Mammalian Phenotype (MP)	abnormal hematopoietic cell number	0.002529	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal renal/urinary system physiology	0.01663	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal renal/urinary system morphology	0.03338	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal professional antigen presenting cell physiology	0.04409	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal immune serum protein physiology	0.05743	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal inflammatory response	0.07893	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal leukocyte physiology	0.1055	Moderately Informative	Inherited
Mammalian Phenotype (MP)	increased leukocyte cell number	0.00009811	Informative	Direct
Mammalian Phenotype (MP)	abnormal renal corpuscle morphology	0.002511	Informative	Inherited
Mammalian Phenotype (MP)	autoimmune response	0.004009	Informative	Inherited
Mammalian Phenotype (MP)	abnormal kidney physiology	0.004009	Informative	Inherited
Mammalian Phenotype (MP)	abnormal humoral immune response	0.01085	Informative	Inherited
Mammalian Phenotype (MP)	increased anti-nuclear antigen antibody level	0.00009908	Highly Informative	Direct
Mammalian Phenotype (MP)	renal/urinary system inflammation	0.0004796	Highly Informative	Direct
Mammalian Phenotype (MP)	increased IgG level	0.0007057	Highly Informative	Direct
Mammalian Phenotype (MP)	abnormal IgG1 level	0.0008302	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

WP

Worm Phenotype (WP)

	WP term	FDR (all)	SDWP (four levels)	Annotation (direct or inherited)
Worm Phenotype (WP)	growth variant	0	--	Direct
Worm Phenotype (WP)	postembryonic development variant	0	--	Direct
Worm Phenotype (WP)	embryonic lethal	0	--	Direct
Worm Phenotype (WP)	lethal	0	--	Direct
Worm Phenotype (WP)	fertility variant	0	--	Direct
Worm Phenotype (WP)	development variant	0	--	Direct
Worm Phenotype (WP)	morphology variant	0	--	Direct
Worm Phenotype (WP)	organism development variant	0	--	Direct
Worm Phenotype (WP)	organ system physiology variant	0	--	Direct
Worm Phenotype (WP)	organism physiology variant	0	--	Direct
Worm Phenotype (WP)	organism homeostasis metabolism variant	0	--	Direct
Worm Phenotype (WP)	reproductive system physiology variant	0	--	Direct
Worm Phenotype (WP)	maternal sterile	0	--	Direct
Worm Phenotype (WP)	hermaphrodite sterile	0	--	Direct
Worm Phenotype (WP)	embryonic development variant	0	--	Direct
Worm Phenotype (WP)	hermaphrodite fertility variant	0	--	Direct
Worm Phenotype (WP)	hermaphrodite fertility reduced	0	--	Direct
Worm Phenotype (WP)	fertility reduced	0	--	Direct
Worm Phenotype (WP)	rachis narrow	0.000001963	--	Direct
Worm Phenotype (WP)	mRNA surveillance defective	0.000003045	--	Direct
Worm Phenotype (WP)	nuclei small	0.000008588	--	Direct
Worm Phenotype (WP)	meiotic progression prophase variant	0.0000111	--	Direct
Worm Phenotype (WP)	meiotic progression during oogenesis variant	0.00002306	--	Direct
Worm Phenotype (WP)	germ cell compartment morphology variant	0.00003455	--	Direct
Worm Phenotype (WP)	oogenesis variant	0.00008159	--	Direct
Worm Phenotype (WP)	meiosis variant	0.0002352	--	Direct
Worm Phenotype (WP)	gonad morphology variant	0.0002502	--	Direct
Worm Phenotype (WP)	gene expression variant	0.001648	--	Inherited
Worm Phenotype (WP)	RNA metabolism variant	0.001722	--	Inherited
Worm Phenotype (WP)	response to bacteria variant	0.007002	--	Inherited
Worm Phenotype (WP)	cell type morphology variant	0.01238	--	Inherited
Worm Phenotype (WP)	cell component morphology variant	0.01719	--	Inherited
Worm Phenotype (WP)	gametogenesis variant	0.06776	--	Inherited
Worm Phenotype (WP)	behavior variant	0.1112	--	Inherited
Worm Phenotype (WP)	transgene expression variant	0.5166	--	Inherited
Worm Phenotype (WP)	physiology variant	1	--	Inherited
Worm Phenotype (WP)	sterile	1	--	Inherited
Worm Phenotype (WP)	cell physiology variant	0.0003441	Least Informative	Direct
Worm Phenotype (WP)	cell development variant	0.01055	Least Informative	Inherited
Worm Phenotype (WP)	organism metabolism processing variant	0.01125	Least Informative	Inherited
Worm Phenotype (WP)	organism environmental stimulus response variant	0.03513	Least Informative	Inherited
Worm Phenotype (WP)	organ system morphology variant	0.03783	Least Informative	Inherited
Worm Phenotype (WP)	cell morphology variant	0.04097	Least Informative	Inherited
Worm Phenotype (WP)	organism behavior variant	0.1084	Least Informative	Inherited
Worm Phenotype (WP)	germ cell differentiation variant	0.000391	Moderately Informative	Direct
Worm Phenotype (WP)	early embryonic lethal	0.0005252	Moderately Informative	Direct
Worm Phenotype (WP)	pattern of transgene expression variant	0.0008126	Moderately Informative	Direct
Worm Phenotype (WP)	metabolic pathway variant	0.0009659	Moderately Informative	Direct
Worm Phenotype (WP)	germ cell morphology variant	0.001158	Moderately Informative	Inherited
Worm Phenotype (WP)	germ cell development variant	0.003171	Moderately Informative	Inherited
Worm Phenotype (WP)	reproductive system morphology variant	0.004431	Moderately Informative	Inherited
Worm Phenotype (WP)	feeding behavior variant	0.006177	Moderately Informative	Inherited
Worm Phenotype (WP)	cell cycle variant	0.03758	Moderately Informative	Inherited
Worm Phenotype (WP)	cell homeostasis metabolism variant	0.07622	Moderately Informative	Inherited
Worm Phenotype (WP)	cell division variant	0.1435	Moderately Informative	Inherited
Worm Phenotype (WP)	pachytene progression during oogenesis variant	0.000002293	Informative	Direct
Worm Phenotype (WP)	diplotene progression during oogenesis variant	0.000002447	Informative	Direct
Worm Phenotype (WP)	germ cell compartment expansion variant	0.00001236	Informative	Direct
Worm Phenotype (WP)	rachis morphology variant	0.00001373	Informative	Direct
Worm Phenotype (WP)	oocyte morphology variant	0.00009011	Informative	Direct
Worm Phenotype (WP)	avoids bacterial lawn	0.0004813	Informative	Direct
Worm Phenotype (WP)	RNA expression variant	0.01859	Informative	Inherited
Worm Phenotype (WP)	gonad vesiculated	0.0000005255	Highly Informative	Direct
Worm Phenotype (WP)	pachytene region organization variant	0.000001253	Highly Informative	Direct
Worm Phenotype (WP)	oocyte number decreased	0.000002722	Highly Informative	Direct
Worm Phenotype (WP)	RNA processing variant	0.00001039	Highly Informative	Direct
Worm Phenotype (WP)	nuclear appearance variant	0.005016	Highly Informative	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

YP

Yeast Phenotype (YP)

	YP term	FDR (all)	SDYP (four levels)	Annotation (direct or inherited)
Yeast Phenotype (YP)	cellular processes	0	--	Direct
Yeast Phenotype (YP)	stress resistance	0	--	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

FP

Fly Phenotype (FP)

	FP term	FDR (all)	SDFP (four levels)	Annotation (direct or inherited)
Fly Phenotype (FP)	phenotype	0	--	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

FA

Fly Anatomy (FA)

	FA term	FDR (all)	SDFA (four levels)	Annotation (direct or inherited)
Fly Anatomy (FA)	organism	0	--	Direct
Fly Anatomy (FA)	organ system	0	--	Direct
Fly Anatomy (FA)	multicellular structure	0	--	Direct
Fly Anatomy (FA)	anatomical structure	1	--	Inherited
Fly Anatomy (FA)	material anatomical entity	1	--	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

XA

Xenopus Anatomy (XA)

	XA term	FDR (all)	SDXA (four levels)	Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)	head region	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical structure	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical group	0	--	Direct
Xenopus ANatomical entity (XAN)	organism subdivision	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical region	0	--	Direct
Xenopus ANatomical entity (XAN)	multicellular anatomical structure	0	--	Direct
Xenopus ANatomical entity (XAN)	whole organism	1	--	Inherited
Xenopus ANatomical entity (XAN)	head	0	Least Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

EC

Enzyme Commission (EC)

	EC term	FDR (all)	SDEC (four levels)	Annotation (direct or inherited)
Enzyme Commission (EC)	Methyltransferases	0	--	Direct
Enzyme Commission (EC)	23S rRNA (guanosine(2251)-2'-O)-methyltransferase	0	--	Direct
Enzyme Commission (EC)	Transferases	0.00000000003133	--	Direct
Enzyme Commission (EC)	Acting on ester bonds	0.07769	--	Inherited
Enzyme Commission (EC)	Hydrolases	1	Least Informative	Inherited
Enzyme Commission (EC)	Transferring one-carbon groups	0	Moderately Informative	Direct
Enzyme Commission (EC)	Endoribonucleases producing 5'-phosphomonoesters	0.0001591	Informative	Direct
Enzyme Commission (EC)	Ribonuclease P	0.0000001117	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

CC

CTD Chemicals (CC)

	CC term	FDR (all)	SDCC (four levels)	Annotation (direct or inherited)
CTD Chemicals (CC)	Heterocyclic Compounds, Fused-Ring	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds, 1-Ring	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds, 2-Ring	0	--	Direct
CTD Chemicals (CC)	Inorganic Chemicals	0	--	Direct
CTD Chemicals (CC)	Organic Chemicals	0	--	Direct
CTD Chemicals (CC)	Uracil	0.05506	--	Inherited
CTD Chemicals (CC)	Quinolines	0.178	--	Inherited
CTD Chemicals (CC)	Hydrocarbons, Chlorinated	0.4112	--	Inherited
CTD Chemicals (CC)	Hydrocarbons	0.4501	--	Inherited
CTD Chemicals (CC)	Toxins, Biological	0.9859	--	Inherited
CTD Chemicals (CC)	Pyrimidines	0.6066	Least Informative	Inherited
CTD Chemicals (CC)	Azoles	1	Least Informative	Inherited
CTD Chemicals (CC)	Biological Factors	1	Least Informative	Inherited
CTD Chemicals (CC)	Hydrocarbons, Halogenated	0.007035	Moderately Informative	Inherited
CTD Chemicals (CC)	Bacterial Toxins	0.07537	Moderately Informative	Inherited
CTD Chemicals (CC)	Pyrimidinones	0.08605	Moderately Informative	Inherited
CTD Chemicals (CC)	Pyrroles	0.4497	Moderately Informative	Inherited
CTD Chemicals (CC)	Benzimidazoles	0.004439	Informative	Inherited
CTD Chemicals (CC)	Quinolones	0.008567	Informative	Inherited
CTD Chemicals (CC)	Piperazines	0.02119	Informative	Inherited
CTD Chemicals (CC)	5-(4-methylpiperazin-1-yl)-2-(2'-(3,4-dimethoxyphenyl)-5'-benzimidazolyl)benzimidazole	0.0000007907	Highly Informative	Direct
CTD Chemicals (CC)	7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one	0.00002517	Highly Informative	Direct
CTD Chemicals (CC)	chloropicrin	0.00005306	Highly Informative	Direct
CTD Chemicals (CC)	cylindrospermopsin	0.0006593	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

Distribution on sTOL

Plot distribution on species Tree Of Life (sTOL) for this domain, i.e., present or absent across genomes/tips

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L30e-like superfamily