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Actin depolymerizing proteins superfamily

Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Gelsolin-like [ 55752] (3)
Superfamily:   Actin depolymerizing proteins [ 55753] (2)
Families:   Gelsolin-like [ 55754] (4)
  Cofilin-like [ 55762] (7)

HP

Human Phenotype (HP)

HP term FDR (all) SDHP (four levels) Annotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of head or neck0--Direct
Phenotypic Abnormality (PA)Abnormality of the mouth0--Direct
Phenotypic Abnormality (PA)Abnormality of the face0--Direct
Phenotypic Abnormality (PA)Abnormality of the nervous system0--Direct
Phenotypic Abnormality (PA)Abnormal peripheral nervous system morphology0--Direct
Phenotypic Abnormality (PA)Abnormal muscle physiology0--Direct
Phenotypic Abnormality (PA)Abnormal oral morphology0--Direct
Phenotypic Abnormality (PA)Abnormality of the head0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the eye0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of metabolism/homeostasis0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the musculature0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of nervous system physiology0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of nervous system morphology0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the digestive system0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the respiratory system0Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormal eye physiology0Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormality of movement0Moderately InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

WP

Worm Phenotype (WP)

WP term FDR (all) SDWP (four levels) Annotation (direct or inherited)
Worm Phenotype (WP)postembryonic development variant0--Direct
Worm Phenotype (WP)embryonic lethal0--Direct
Worm Phenotype (WP)lethal0--Direct
Worm Phenotype (WP)fertility variant0--Direct
Worm Phenotype (WP)development variant0--Direct
Worm Phenotype (WP)morphology variant0--Direct
Worm Phenotype (WP)organism development variant0--Direct
Worm Phenotype (WP)organism morphology variant0--Direct
Worm Phenotype (WP)organ system physiology variant0--Direct
Worm Phenotype (WP)reproductive system physiology variant0--Direct
Worm Phenotype (WP)maternal sterile0--Direct
Worm Phenotype (WP)hermaphrodite sterile0--Direct
Worm Phenotype (WP)embryonic development variant0--Direct
Worm Phenotype (WP)hermaphrodite fertility variant0--Direct
Worm Phenotype (WP)hermaphrodite fertility reduced0--Direct
Worm Phenotype (WP)fertility reduced0--Direct
Worm Phenotype (WP)physiology variant1--Inherited
Worm Phenotype (WP)sterile1--Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

YP

Yeast Phenotype (YP)

YP term FDR (all) SDYP (four levels) Annotation (direct or inherited)
Yeast Phenotype (YP)cellular processes0--Direct
Yeast Phenotype (YP)stress resistance0--Direct
Yeast Phenotype (YP)competitive fitness0--Direct
Yeast Phenotype (YP)fitness0--Direct
Yeast Phenotype (YP)resistance to chemicals0Least InformativeDirect
Yeast Phenotype (YP)metabolism and growth0Least InformativeDirect
Yeast Phenotype (YP)intracellular transport0.001344InformativeInherited
Yeast Phenotype (YP)endocytosis0.00009326Highly InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

FA

Fly Anatomy (FA)

FA term FDR (all) SDFA (four levels) Annotation (direct or inherited)
Fly Anatomy (FA)organism0--Direct
Fly Anatomy (FA)multicellular structure0--Direct
Fly Anatomy (FA)somatic cell of ovariole0.002599--Inherited
Fly Anatomy (FA)egg chamber0.009571--Inherited
Fly Anatomy (FA)ovariole0.01831--Inherited
Fly Anatomy (FA)ovary0.02104--Inherited
Fly Anatomy (FA)germline cyst0.02208--Inherited
Fly Anatomy (FA)female reproductive system0.02222--Inherited
Fly Anatomy (FA)female organism0.02804--Inherited
Fly Anatomy (FA)reproductive system0.05235--Inherited
Fly Anatomy (FA)somatic cell0.1205--Inherited
Fly Anatomy (FA)portion of tissue0.1316--Inherited
Fly Anatomy (FA)organ system0.5433--Inherited
Fly Anatomy (FA)anatomical structure1--Inherited
Fly Anatomy (FA)material anatomical entity1--Inherited
Fly Anatomy (FA)cell0.1796Least InformativeInherited
Fly Anatomy (FA)multi-tissue structure0.4767Least InformativeInherited
Fly Anatomy (FA)epithelium0.009678Moderately InformativeInherited
Fly Anatomy (FA)female-specific anatomical entity0.02361Moderately InformativeInherited
Fly Anatomy (FA)gonad0.0507Moderately InformativeInherited
Fly Anatomy (FA)female germline cyst0.01024InformativeInherited
Fly Anatomy (FA)epithelial cell0.01206InformativeInherited
Fly Anatomy (FA)follicle cell0.0009855Highly InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

ZA

Zebrafish Anatomy (ZA)

ZA term FDR (all) SDZA (four levels) Annotation (direct or inherited)
Zebrafish Anatomy (ZA)anatomical group0--Direct
Zebrafish Anatomy (ZA)anatomical structure1--Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

XA

Xenopus Anatomy (XA)

XA term FDR (all) SDXA (four levels) Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)anatomical structure0--Direct
Xenopus ANatomical entity (XAN)anatomical group0--Direct
Xenopus ANatomical entity (XAN)bone element0.0000875--Direct
Xenopus ANatomical entity (XAN)skeletal tissue0.00009674--Direct
Xenopus ANatomical entity (XAN)skeleton0.0001806--Direct
Xenopus ANatomical entity (XAN)skeletal element0.001849--Inherited
Xenopus ANatomical entity (XAN)anatomical cluster0.3011--Inherited
Xenopus ANatomical entity (XAN)compound organ0.34--Inherited
Xenopus ANatomical entity (XAN)multicellular anatomical structure0.7117--Inherited
Xenopus ANatomical entity (XAN)anatomical system1--Inherited
Xenopus ANatomical entity (XAN)whole organism1--Inherited
Xenopus ANatomical entity (XAN)tissue0.05426Least InformativeInherited
Xenopus ANatomical entity (XAN)musculoskeletal system0.008614Moderately InformativeInherited
Xenopus ANatomical entity (XAN)connective tissue0.0006338InformativeDirect
Xenopus ANatomical entity (XAN)skeletal system0.001144InformativeInherited
Xenopus ANatomical entity (XAN)solid compound organ0.01845InformativeInherited
Xenopus ANatomical entity (XAN)bone tissue0.00008409Highly InformativeDirect
 
XA term FDR (all) SDXA (four levels) Annotation (direct or inherited)
Xenopus DEvelopment stage (XDE)NF stage0--Direct
Xenopus DEvelopment stage (XDE)metamorphosing tadpole stage0.003534--Inherited
Xenopus DEvelopment stage (XDE)tadpole stage0.008122--Inherited
Xenopus DEvelopment stage (XDE)post-embryonic stage0.009481Least InformativeInherited
Xenopus DEvelopment stage (XDE)climax stage0.001627Moderately InformativeInherited
Xenopus DEvelopment stage (XDE)NF stage 660.0003579InformativeDirect

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AP

Arabidopsis Plant Ontology (AP)

AP term FDR (all) SDAP (four levels) Annotation (direct or inherited)
Plant ANatomical entity (PAN)plant cell0--Direct
Plant ANatomical entity (PAN)shoot system0--Direct
Plant ANatomical entity (PAN)plant organ0--Direct
Plant ANatomical entity (PAN)multi-tissue plant structure0--Direct
Plant ANatomical entity (PAN)collective plant structure0--Direct
Plant ANatomical entity (PAN)plant structure1--Inherited
Plant ANatomical entity (PAN)collective plant organ structure1--Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

KW

UniProtKB KeyWords (KW)

KW term FDR (all) SDKW (four levels) Annotation (direct or inherited)
Molecular functionActin-binding0Highly InformativeDirect

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CC

CTD Chemicals (CC)

CC term FDR (all) SDCC (four levels) Annotation (direct or inherited)
CTD Chemicals (CC)Heterocyclic Compounds, Fused-Ring0--Direct
CTD Chemicals (CC)Heterocyclic Compounds0--Direct
CTD Chemicals (CC)Heterocyclic Compounds, 1-Ring0--Direct
CTD Chemicals (CC)Heterocyclic Compounds, 2-Ring0--Direct
CTD Chemicals (CC)Hydrocarbons0--Direct
CTD Chemicals (CC)Hydrocarbons, Aromatic0--Direct
CTD Chemicals (CC)Hydrocarbons, Cyclic0--Direct
CTD Chemicals (CC)Inorganic Chemicals0--Direct
CTD Chemicals (CC)Organic Chemicals0--Direct
CTD Chemicals (CC)Tobacco Smoke Pollution0.0000003089--Direct
CTD Chemicals (CC)Complex Mixtures0.00339Least InformativeInherited
CTD Chemicals (CC)Particulate Matter0.004782Moderately InformativeInherited
CTD Chemicals (CC)Smoke0.000001392InformativeDirect

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Distribution on sTOL

Plot distribution on species Tree Of Life (sTOL) for this domain, i.e., present or absent across genomes/tips
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