Kringle modules family

DO

Disease Ontology (DO)

	DO term	FDR (all)	SDDO (four levels)	Annotation (direct or inherited)
Disease Ontology (DO)	arteriosclerotic cardiovascular disease	0.000001997	--	Direct
Disease Ontology (DO)	myocardial infarction	0.00001002	--	Direct
Disease Ontology (DO)	cerebral degeneration	0.00005036	--	Direct
Disease Ontology (DO)	blood coagulation disease	0.0002161	--	Direct
Disease Ontology (DO)	vascular disease	0.0005149	--	Direct
Disease Ontology (DO)	central nervous system disease	0.001056	--	Inherited
Disease Ontology (DO)	pancreatic adenocarcinoma	0.001746	--	Inherited
Disease Ontology (DO)	cardiovascular system disease	0.001861	--	Inherited
Disease Ontology (DO)	arteriosclerosis	0.002784	--	Inherited
Disease Ontology (DO)	breast ductal carcinoma	0.003698	--	Inherited
Disease Ontology (DO)	pancreatic cancer	0.005391	--	Inherited
Disease Ontology (DO)	breast cancer	0.069	--	Inherited
Disease Ontology (DO)	thoracic cancer	0.1564	--	Inherited
Disease Ontology (DO)	disease of anatomical entity	0.1742	--	Inherited
Disease Ontology (DO)	cancer	0.4064	--	Inherited
Disease Ontology (DO)	disease of cellular proliferation	0.4367	--	Inherited
Disease Ontology (DO)	brain disease	0.4522	--	Inherited
Disease Ontology (DO)	pancreatic carcinoma	1	--	Inherited
Disease Ontology (DO)	nervous system disease	0.0121	Least Informative	Inherited
Disease Ontology (DO)	organ system cancer	0.0902	Least Informative	Inherited
Disease Ontology (DO)	artery disease	0.0001827	Moderately Informative	Direct
Disease Ontology (DO)	hematopoietic system disease	0.0118	Moderately Informative	Inherited
Disease Ontology (DO)	atherosclerosis	0.000001955	Informative	Direct
Disease Ontology (DO)	coronary artery disease	0.02079	Informative	Inherited
Disease Ontology (DO)	breast carcinoma	0.03901	Informative	Inherited
Disease Ontology (DO)	endocrine gland cancer	0.05745	Informative	Inherited
Disease Ontology (DO)	leukodystrophy	0.00002088	Highly Informative	Direct
Disease Ontology (DO)	pancreatic ductal adenocarcinoma	0.0003738	Highly Informative	Direct
Disease Ontology (DO)	invasive ductal carcinoma	0.0008141	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

HP

Human Phenotype (HP)

	HP term	FDR (all)	SDHP (four levels)	Annotation (direct or inherited)
Phenotypic Abnormality (PA)	Venous thrombosis	0.001251	--	Inherited
Phenotypic Abnormality (PA)	Abnormal thrombosis	0.02131	--	Inherited
Phenotypic Abnormality (PA)	Abnormality of blood and blood-forming tissues	0.02868	Moderately Informative	Inherited
Phenotypic Abnormality (PA)	Abnormality of coagulation	0.000823	Informative	Direct
Phenotypic Abnormality (PA)	Deep venous thrombosis	0.000004176	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

MP

Mouse Phenotype (MP)

	MP term	FDR (all)	SDMP (four levels)	Annotation (direct or inherited)
Mammalian Phenotype (MP)	decreased susceptibility to induced choroidal neovascularization	0.0000002191	--	Direct
Mammalian Phenotype (MP)	choroidal neovascularization	0.000001693	--	Direct
Mammalian Phenotype (MP)	abnormal acute phase protein level	0.000005981	--	Direct
Mammalian Phenotype (MP)	rectal prolapse	0.000009979	--	Direct
Mammalian Phenotype (MP)	abnormal choroid vasculature morphology	0.00002404	--	Direct
Mammalian Phenotype (MP)	abnormal rectum morphology	0.00003158	--	Direct
Mammalian Phenotype (MP)	abnormal optic choroid morphology	0.00003158	--	Direct
Mammalian Phenotype (MP)	pathological neovascularization	0.0003584	--	Direct
Mammalian Phenotype (MP)	polydactyly	0.0004613	--	Direct
Mammalian Phenotype (MP)	respiratory distress	0.0005538	--	Direct
Mammalian Phenotype (MP)	abnormal hemostasis	0.0007027	--	Direct
Mammalian Phenotype (MP)	liver fibrosis	0.0007431	--	Direct
Mammalian Phenotype (MP)	abnormal uvea morphology	0.00235	--	Inherited
Mammalian Phenotype (MP)	digestive/alimentary phenotype	0.003572	--	Inherited
Mammalian Phenotype (MP)	abnormal digit morphology	0.006936	--	Inherited
Mammalian Phenotype (MP)	abnormal liver morphology	0.01709	--	Inherited
Mammalian Phenotype (MP)	abnormal cardiovascular system morphology	0.02257	--	Inherited
Mammalian Phenotype (MP)	abnormal hepatobiliary system morphology	0.02348	--	Inherited
Mammalian Phenotype (MP)	abnormal limb morphology	0.02369	--	Inherited
Mammalian Phenotype (MP)	skeleton phenotype	0.02863	--	Inherited
Mammalian Phenotype (MP)	abnormal immune system physiology	0.1327	--	Inherited
Mammalian Phenotype (MP)	vision/eye phenotype	0.1672	--	Inherited
Mammalian Phenotype (MP)	abnormal respiratory system physiology	0.1839	--	Inherited
Mammalian Phenotype (MP)	homeostasis/metabolism phenotype	0.195	--	Inherited
Mammalian Phenotype (MP)	abnormal respiration	0.2425	--	Inherited
Mammalian Phenotype (MP)	abnormal blood homeostasis	0.2505	--	Inherited
Mammalian Phenotype (MP)	abnormal skeleton morphology	0.9709	--	Inherited
Mammalian Phenotype (MP)	cardiovascular system phenotype	0.07141	Least Informative	Inherited
Mammalian Phenotype (MP)	immune system phenotype	0.3659	Least Informative	Inherited
Mammalian Phenotype (MP)	abnormal homeostasis	0.9565	Least Informative	Inherited
Mammalian Phenotype (MP)	respiratory system phenotype	0.01771	Moderately Informative	Inherited
Mammalian Phenotype (MP)	liver/biliary system phenotype	0.03533	Moderately Informative	Inherited
Mammalian Phenotype (MP)	limbs/digits/tail phenotype	0.04908	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal protein level	0.07219	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal eye morphology	0.137	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal bone structure	0.2254	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal blood vessel morphology	0.3222	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal cardiovascular system physiology	0.3772	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal immune serum protein physiology	0.4514	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal digestive system morphology	0.9003	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal eyelid morphology	0.0005751	Informative	Direct
Mammalian Phenotype (MP)	abnormal blood coagulation	0.0006759	Informative	Direct
Mammalian Phenotype (MP)	abnormal respiratory function	0.003763	Informative	Inherited
Mammalian Phenotype (MP)	abnormal innate immunity	0.03263	Informative	Inherited
Mammalian Phenotype (MP)	abnormal blood vessel physiology	0.06946	Informative	Inherited
Mammalian Phenotype (MP)	abnormal intestine morphology	0.1108	Informative	Inherited
Mammalian Phenotype (MP)	abnormal autopod morphology	0.1266	Informative	Inherited
Mammalian Phenotype (MP)	abnormal bone volume	0.0009441	Highly Informative	Direct
Mammalian Phenotype (MP)	abnormal breathing pattern	0.001908	Highly Informative	Inherited
Mammalian Phenotype (MP)	abnormal large intestine morphology	0.002481	Highly Informative	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

XA

Xenopus Anatomy (XA)

	XA term	FDR (all)	SDXA (four levels)	Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)	anatomical structure	0	--	Direct
Xenopus ANatomical entity (XAN)	neural plate	0.05597	--	Inherited
Xenopus ANatomical entity (XAN)	primary germ layer	0.7159	--	Inherited
Xenopus ANatomical entity (XAN)	multicellular anatomical structure	0.787	--	Inherited
Xenopus ANatomical entity (XAN)	whole organism	1	--	Inherited
Xenopus ANatomical entity (XAN)	embryo	0.5605	Least Informative	Inherited
Xenopus ANatomical entity (XAN)	tissue	0.6664	Least Informative	Inherited
Xenopus ANatomical entity (XAN)	ectoderm	1	Moderately Informative	Inherited
Xenopus ANatomical entity (XAN)	neuroectoderm	0.1469	Informative	Inherited
Xenopus ANatomical entity (XAN)	neural groove	0.0001596	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

EC

Enzyme Commission (EC)

	EC term	FDR (all)	SDEC (four levels)	Annotation (direct or inherited)
Enzyme Commission (EC)	Plasmin	0	--	Direct
Enzyme Commission (EC)	T-plasminogen activator	0.000000000000001283	--	Direct
Enzyme Commission (EC)	U-plasminogen activator	0.00000000000002706	--	Direct
Enzyme Commission (EC)	Coagulation factor XIIa	0.0000000002006	--	Direct
Enzyme Commission (EC)	Thrombin	0.0000000002006	--	Direct
Enzyme Commission (EC)	Protein-tyrosine kinases	0.0000000005556	--	Direct
Enzyme Commission (EC)	Transferring phosphorus-containing groups	0.7069	--	Inherited
Enzyme Commission (EC)	Hydrolases	0	Least Informative	Direct
Enzyme Commission (EC)	Transferases	1	Least Informative	Inherited
Enzyme Commission (EC)	Acting on peptide bonds (peptidases)	0	Moderately Informative	Direct
Enzyme Commission (EC)	Serine endopeptidases	0	Informative	Direct
Enzyme Commission (EC)	Receptor protein-tyrosine kinase	0.00000000001543	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

CD

CTD Diseases (CD)

	CD term	FDR (all)	SDCD (four levels)	Annotation (direct or inherited)
CTD Diseases (CD)	Embolism and Thrombosis	0.00000000008692	--	Direct
CTD Diseases (CD)	Intracranial Thrombosis	0.0000001605	--	Direct
CTD Diseases (CD)	Stroke	0.00004297	--	Direct
CTD Diseases (CD)	Cerebral Arterial Diseases	0.00005692	--	Direct
CTD Diseases (CD)	Cerebral Infarction	0.00006156	--	Direct
CTD Diseases (CD)	Hematologic Diseases	0.0003603	--	Direct
CTD Diseases (CD)	Infarction	0.001903	--	Inherited
CTD Diseases (CD)	Cardiovascular Diseases	0.004636	--	Inherited
CTD Diseases (CD)	Ischemia	0.007113	--	Inherited
CTD Diseases (CD)	Intracranial Arterial Diseases	0.01401	--	Inherited
CTD Diseases (CD)	Brain Infarction	0.0154	--	Inherited
CTD Diseases (CD)	Blood Coagulation Disorders	0.01865	--	Inherited
CTD Diseases (CD)	Thromboembolism	0.02132	--	Inherited
CTD Diseases (CD)	Pathologic Processes	0.11	--	Inherited
CTD Diseases (CD)	Central Nervous System Diseases	0.112	--	Inherited
CTD Diseases (CD)	Congenital, Hereditary, and Neonatal Diseases and Abnormalities	0.1327	--	Inherited
CTD Diseases (CD)	Neurologic Manifestations	0.1685	--	Inherited
CTD Diseases (CD)	Brain Ischemia	0.1715	--	Inherited
CTD Diseases (CD)	Neoplasms	0.197	Least Informative	Inherited
CTD Diseases (CD)	Genetic Diseases, Inborn	0.2584	Least Informative	Inherited
CTD Diseases (CD)	Pathological Conditions, Signs and Symptoms	0.3466	Least Informative	Inherited
CTD Diseases (CD)	Nervous System Diseases	0.3477	Least Informative	Inherited
CTD Diseases (CD)	Hemic and Lymphatic Diseases	0.003849	Moderately Informative	Inherited
CTD Diseases (CD)	Brain Diseases	0.06746	Moderately Informative	Inherited
CTD Diseases (CD)	Vascular Diseases	0.08074	Moderately Informative	Inherited
CTD Diseases (CD)	Signs and Symptoms	0.204	Moderately Informative	Inherited
CTD Diseases (CD)	Blood Coagulation Disorders, Inherited	0.00007305	Informative	Direct
CTD Diseases (CD)	Hemorrhage	0.0009645	Informative	Direct
CTD Diseases (CD)	Cerebrovascular Disorders	0.004859	Informative	Inherited
CTD Diseases (CD)	Necrosis	0.01097	Informative	Inherited
CTD Diseases (CD)	Neoplastic Processes	0.01503	Informative	Inherited
CTD Diseases (CD)	Coagulation Protein Disorders	0.000004819	Highly Informative	Direct
CTD Diseases (CD)	Infarction, Middle Cerebral Artery	0.00002591	Highly Informative	Direct
CTD Diseases (CD)	Pain	0.0002142	Highly Informative	Direct
CTD Diseases (CD)	Neoplasm Metastasis	0.0005732	Highly Informative	Direct
CTD Diseases (CD)	Intracranial Embolism and Thrombosis	0.0008396	Highly Informative	Direct
CTD Diseases (CD)	Thrombophilia	0.0009946	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

CC

CTD Chemicals (CC)

	CC term	FDR (all)	SDCC (four levels)	Annotation (direct or inherited)
CTD Chemicals (CC)	Heterocyclic Compounds, Fused-Ring	0	--	Direct
CTD Chemicals (CC)	Carboxylic Acids	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds, 1-Ring	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds, 2-Ring	0	--	Direct
CTD Chemicals (CC)	Inorganic Chemicals	0	--	Direct
CTD Chemicals (CC)	Organic Chemicals	0	--	Direct
CTD Chemicals (CC)	Polycyclic Compounds	0	--	Direct
CTD Chemicals (CC)	Pyrans	0	--	Direct
CTD Chemicals (CC)	Toxins, Biological	0	--	Direct
CTD Chemicals (CC)	ethinyl estradiol-desogestrel combination	0.000000472	--	Direct
CTD Chemicals (CC)	Medroxyprogesterone Acetate	0.00001197	--	Direct
CTD Chemicals (CC)	Medroxyprogesterone	0.00001244	--	Direct
CTD Chemicals (CC)	6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid	0.00003273	--	Direct
CTD Chemicals (CC)	Oxygen Compounds	0.0005387	--	Direct
CTD Chemicals (CC)	Estradiol	0.0007211	--	Direct
CTD Chemicals (CC)	Norpregnenes	0.0007814	--	Direct
CTD Chemicals (CC)	Gonadal Hormones	0.001519	--	Inherited
CTD Chemicals (CC)	Hormones, Hormone Substitutes, and Hormone Antagonists	0.001892	--	Inherited
CTD Chemicals (CC)	Pregnenediones	0.002321	--	Inherited
CTD Chemicals (CC)	Hydroxyprogesterones	0.00262	--	Inherited
CTD Chemicals (CC)	Polysaccharides	0.003411	--	Inherited
CTD Chemicals (CC)	Norpregnatrienes	0.004115	--	Inherited
CTD Chemicals (CC)	Pregnenes	0.009249	--	Inherited
CTD Chemicals (CC)	Pharmacologic Actions	0.009672	--	Inherited
CTD Chemicals (CC)	Estrogenic Steroids, Alkylated	0.0433	--	Inherited
CTD Chemicals (CC)	Corpus Luteum Hormones	0.04972	--	Inherited
CTD Chemicals (CC)	Progesterone Congeners	0.05209	--	Inherited
CTD Chemicals (CC)	Physiological Effects of Drugs	0.05458	--	Inherited
CTD Chemicals (CC)	Estradiol Congeners	0.1474	--	Inherited
CTD Chemicals (CC)	Estrenes	1	--	Inherited
CTD Chemicals (CC)	Hormones	1	--	Inherited
CTD Chemicals (CC)	Norpregnanes	1	--	Inherited
CTD Chemicals (CC)	Steroids	1	--	Inherited
CTD Chemicals (CC)	Benzopyrans	0	Least Informative	Direct
CTD Chemicals (CC)	Biological Factors	0	Least Informative	Direct
CTD Chemicals (CC)	Electrolytes	0	Least Informative	Direct
CTD Chemicals (CC)	Chemical Actions and Uses	0.01657	Least Informative	Inherited
CTD Chemicals (CC)	Fused-Ring Compounds	0.03031	Least Informative	Inherited
CTD Chemicals (CC)	Carbohydrates	0.3011	Least Informative	Inherited
CTD Chemicals (CC)	Gases	0.0002047	Moderately Informative	Direct
CTD Chemicals (CC)	Estranes	0.05171	Moderately Informative	Inherited
CTD Chemicals (CC)	Pregnanes	0.4273	Moderately Informative	Inherited
CTD Chemicals (CC)	Gonadal Steroid Hormones	1	Moderately Informative	Inherited
CTD Chemicals (CC)	Acids, Heterocyclic	0.0005347	Informative	Direct
CTD Chemicals (CC)	Progesterone	0.001524	Informative	Inherited
CTD Chemicals (CC)	Quinazolines	0.01573	Informative	Inherited
CTD Chemicals (CC)	Norsteroids	0.05285	Informative	Inherited
CTD Chemicals (CC)	Chromans	0.1929	Informative	Inherited
CTD Chemicals (CC)	Gestodene	0.0000003506	Highly Informative	Direct
CTD Chemicals (CC)	Desogestrel	0.000003682	Highly Informative	Direct
CTD Chemicals (CC)	Quinazolinones	0.00003947	Highly Informative	Direct
CTD Chemicals (CC)	Norgestrel	0.0004042	Highly Informative	Direct
CTD Chemicals (CC)	Glycosaminoglycans	0.0009919	Highly Informative	Direct
CTD Chemicals (CC)	Ethinyl Estradiol	1	Highly Informative	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

Distribution on sTOL

Plot distribution on species Tree Of Life (sTOL) for this domain, i.e., present or absent across genomes/tips

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LINKOUT

Kringle modules family