TNF receptor-like family

DO

Disease Ontology (DO)

	DO term	FDR (all)	SDDO (four levels)	Annotation (direct or inherited)
Disease Ontology (DO)	disease of anatomical entity	0	--	Direct
Disease Ontology (DO)	bone inflammation disease	0.000000000002282	--	Direct
Disease Ontology (DO)	musculoskeletal system disease	0.000000184	--	Direct
Disease Ontology (DO)	kidney disease	0.0000002031	--	Direct
Disease Ontology (DO)	spondyloarthropathy	0.00003029	--	Direct
Disease Ontology (DO)	agammaglobulinemia	0.00003542	--	Direct
Disease Ontology (DO)	pancreatic adenocarcinoma	0.00004836	--	Direct
Disease Ontology (DO)	vascular disease	0.00005575	--	Direct
Disease Ontology (DO)	bone resorption disease	0.00005892	--	Direct
Disease Ontology (DO)	alopecia	0.00008959	--	Direct
Disease Ontology (DO)	breast cancer	0.0001206	--	Direct
Disease Ontology (DO)	endocrine system disease	0.0001552	--	Direct
Disease Ontology (DO)	arteriosclerotic cardiovascular disease	0.0002669	--	Direct
Disease Ontology (DO)	pancreatic cancer	0.00029	--	Direct
Disease Ontology (DO)	immune system cancer	0.0005219	--	Direct
Disease Ontology (DO)	immune system disease	0.0006865	--	Direct
Disease Ontology (DO)	demyelinating disease	0.003036	--	Inherited
Disease Ontology (DO)	thoracic cancer	0.003556	--	Inherited
Disease Ontology (DO)	cardiovascular system disease	0.02093	--	Inherited
Disease Ontology (DO)	B cell deficiency	0.02376	--	Inherited
Disease Ontology (DO)	hair disease	0.03828	--	Inherited
Disease Ontology (DO)	arteriosclerosis	0.05345	--	Inherited
Disease Ontology (DO)	cancer	0.06678	--	Inherited
Disease Ontology (DO)	disease of cellular proliferation	0.07805	--	Inherited
Disease Ontology (DO)	autoimmune disease of endocrine system	0.09741	--	Inherited
Disease Ontology (DO)	bone marrow cancer	0.1179	--	Inherited
Disease Ontology (DO)	central nervous system disease	0.1419	--	Inherited
Disease Ontology (DO)	bone disease	0.2105	--	Inherited
Disease Ontology (DO)	intestinal disease	0.2248	--	Inherited
Disease Ontology (DO)	hypersensitivity reaction disease	0.2306	--	Inherited
Disease Ontology (DO)	pancreatic carcinoma	1	--	Inherited
Disease Ontology (DO)	organ system cancer	0.006323	Least Informative	Inherited
Disease Ontology (DO)	nervous system disease	0.5745	Least Informative	Inherited
Disease Ontology (DO)	connective tissue disease	0.00000000000101	Moderately Informative	Direct
Disease Ontology (DO)	disease by infectious agent	0.0000007239	Moderately Informative	Direct
Disease Ontology (DO)	hypersensitivity reaction type II disease	0.0000009591	Moderately Informative	Direct
Disease Ontology (DO)	hematologic cancer	0.000005252	Moderately Informative	Direct
Disease Ontology (DO)	urinary system disease	0.00004813	Moderately Informative	Direct
Disease Ontology (DO)	integumentary system disease	0.000161	Moderately Informative	Direct
Disease Ontology (DO)	gastrointestinal system disease	0.004173	Moderately Informative	Inherited
Disease Ontology (DO)	neurodegenerative disease	0.008729	Moderately Informative	Inherited
Disease Ontology (DO)	artery disease	0.6807	Moderately Informative	Inherited
Disease Ontology (DO)	arthritis	0.0000000000009404	Informative	Direct
Disease Ontology (DO)	lupus erythematosus	0.0000000006775	Informative	Direct
Disease Ontology (DO)	breast carcinoma	0.00002527	Informative	Direct
Disease Ontology (DO)	multiple sclerosis	0.0001273	Informative	Direct
Disease Ontology (DO)	hypotrichosis	0.0001443	Informative	Direct
Disease Ontology (DO)	atherosclerosis	0.0002617	Informative	Direct
Disease Ontology (DO)	myeloid neoplasm	0.0003402	Informative	Direct
Disease Ontology (DO)	inflammatory bowel disease	0.0009399	Informative	Direct
Disease Ontology (DO)	endocrine gland cancer	0.02862	Informative	Inherited
Disease Ontology (DO)	arthropathy	0.1112	Informative	Inherited
Disease Ontology (DO)	Graves' disease	0.0007054	Highly Informative	Direct
Disease Ontology (DO)	primary immunodeficiency disease	0.05408	Highly Informative	Inherited
Disease Ontology (DO)	bone remodeling disease	0.1381	Highly Informative	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

HP

Human Phenotype (HP)

	HP term	FDR (all)	SDHP (four levels)	Annotation (direct or inherited)
	Variable expressivity	0	--	Direct
	Phenotypic variability	1	--	Inherited
Phenotypic Abnormality (PA)	Abnormal immunoglobulin level	0.00008469	--	Direct
Phenotypic Abnormality (PA)	Abnormality of B cell physiology	0.00009097	--	Direct
Phenotypic Abnormality (PA)	Abnormal cellular phenotype	0.0003205	--	Direct
Phenotypic Abnormality (PA)	Abnormal spleen morphology	0.0004032	--	Direct
Phenotypic Abnormality (PA)	Visceromegaly	0.002169	--	Inherited
Phenotypic Abnormality (PA)	Abnormality of humoral immunity	0.003146	--	Inherited
Phenotypic Abnormality (PA)	Abnormality of abdomen morphology	0.003545	--	Inherited
Phenotypic Abnormality (PA)	Abnormal lymphocyte physiology	0.004287	--	Inherited
Phenotypic Abnormality (PA)	Abnormality of the spleen	0.01266	--	Inherited
Phenotypic Abnormality (PA)	Skin nodule	0.01405	--	Inherited
Phenotypic Abnormality (PA)	Abnormality of the vasculature	0.2825	--	Inherited
Phenotypic Abnormality (PA)	Abnormality of the skin	0.3707	--	Inherited
Phenotypic Abnormality (PA)	Abnormality of skin morphology	0.9517	--	Inherited
Phenotypic Abnormality (PA)	Abnormality of the cardiovascular system	0.03001	Least Informative	Inherited
Phenotypic Abnormality (PA)	Abnormality of the immune system	0.06209	Least Informative	Inherited
Phenotypic Abnormality (PA)	Abnormality of metabolism/homeostasis	0.08287	Least Informative	Inherited
Phenotypic Abnormality (PA)	Abnormality of the integument	0.09639	Least Informative	Inherited
Phenotypic Abnormality (PA)	Abnormality of the digestive system	0.509	Least Informative	Inherited
Phenotypic Abnormality (PA)	Abnormality of the lymphatic system	0.0001996	Moderately Informative	Direct
Phenotypic Abnormality (PA)	Abnormality of immune system physiology	0.0191	Moderately Informative	Inherited
Phenotypic Abnormality (PA)	Abnormality of the abdominal organs	0.03304	Moderately Informative	Inherited
Phenotypic Abnormality (PA)	Localized skin lesion	0.03361	Moderately Informative	Inherited
Phenotypic Abnormality (PA)	Splenomegaly	0.0001123	Informative	Direct
Phenotypic Abnormality (PA)	Abnormal cellular physiology	0.0009945	Informative	Direct
Phenotypic Abnormality (PA)	Subcutaneous nodule	0.0009902	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

MP

Mouse Phenotype (MP)

	MP term	FDR (all)	SDMP (four levels)	Annotation (direct or inherited)
Mammalian Phenotype (MP)	abnormal spleen secondary B follicle morphology	0.0000000000001996	--	Direct
Mammalian Phenotype (MP)	abnormal spleen B cell follicle morphology	0.000000000006928	--	Direct
Mammalian Phenotype (MP)	abnormal lymphocyte physiology	0.0000000008056	--	Direct
Mammalian Phenotype (MP)	increased leukocyte cell number	0.0000000008186	--	Direct
Mammalian Phenotype (MP)	abnormal spleen white pulp morphology	0.000000003566	--	Direct
Mammalian Phenotype (MP)	abnormal mononuclear cell morphology	0.000000008195	--	Direct
Mammalian Phenotype (MP)	abnormal immune system physiology	0.00000002492	--	Direct
Mammalian Phenotype (MP)	abnormal leukocyte morphology	0.0000000574	--	Direct
Mammalian Phenotype (MP)	abnormal immune system cell morphology	0.00000006433	--	Direct
Mammalian Phenotype (MP)	abnormal interleukin secretion	0.0000001006	--	Direct
Mammalian Phenotype (MP)	abnormal blood cell physiology	0.0000001205	--	Direct
Mammalian Phenotype (MP)	abnormal IgG1 level	0.0000001234	--	Direct
Mammalian Phenotype (MP)	absent lymph node germinal center	0.0000005328	--	Direct
Mammalian Phenotype (MP)	abnormal Peyer's patch morphology	0.0000006164	--	Direct
Mammalian Phenotype (MP)	increased susceptibility to autoimmune disorder	0.0000007597	--	Direct
Mammalian Phenotype (MP)	abnormal hematopoietic cell morphology	0.000002164	--	Direct
Mammalian Phenotype (MP)	abnormal negative T cell selection	0.000002909	--	Direct
Mammalian Phenotype (MP)	autoimmune response	0.000008275	--	Direct
Mammalian Phenotype (MP)	abnormal self tolerance	0.000008633	--	Direct
Mammalian Phenotype (MP)	abnormal lymph node germinal center morphology	0.000009052	--	Direct
Mammalian Phenotype (MP)	abnormal lymph node secondary follicle morphology	0.00001037	--	Direct
Mammalian Phenotype (MP)	abnormal nervous system regeneration	0.00001079	--	Direct
Mammalian Phenotype (MP)	pulmonary fibrosis	0.00002351	--	Direct
Mammalian Phenotype (MP)	abnormal definitive hematopoiesis	0.00003121	--	Direct
Mammalian Phenotype (MP)	abnormal bronchial provocation	0.0000531	--	Direct
Mammalian Phenotype (MP)	abnormal phagocyte morphology	0.0000603	--	Direct
Mammalian Phenotype (MP)	abnormal lymph node B cell domain morphology	0.0000722	--	Direct
Mammalian Phenotype (MP)	abnormal IgG2a level	0.00009797	--	Direct
Mammalian Phenotype (MP)	decreased inflammatory response	0.0001303	--	Direct
Mammalian Phenotype (MP)	abnormal intercellular signaling peptide or protein level	0.0001619	--	Direct
Mammalian Phenotype (MP)	enlarged thymus	0.0002374	--	Direct
Mammalian Phenotype (MP)	abnormal bone remodeling	0.0002903	--	Direct
Mammalian Phenotype (MP)	cortical renal glomerulopathies	0.0003057	--	Direct
Mammalian Phenotype (MP)	increased CD4-positive, alpha beta T cell number	0.0003769	--	Direct
Mammalian Phenotype (MP)	abnormal thymus epithelium morphology	0.0004313	--	Direct
Mammalian Phenotype (MP)	abnormal acute inflammation	0.0004826	--	Direct
Mammalian Phenotype (MP)	abnormal liver physiology	0.0008158	--	Direct
Mammalian Phenotype (MP)	increased anti-nuclear antigen antibody level	0.0008409	--	Direct
Mammalian Phenotype (MP)	abnormal ocular surface morphology	0.000909	--	Direct
Mammalian Phenotype (MP)	abnormal gut-associated lymphoid tissue morphology	0.001047	--	Inherited
Mammalian Phenotype (MP)	abnormal humoral immune response	0.001517	--	Inherited
Mammalian Phenotype (MP)	abnormal viscerocranium morphology	0.001754	--	Inherited
Mammalian Phenotype (MP)	craniofacial phenotype	0.002544	--	Inherited
Mammalian Phenotype (MP)	abnormal renal corpuscle morphology	0.003266	--	Inherited
Mammalian Phenotype (MP)	abnormal T cell selection	0.005737	--	Inherited
Mammalian Phenotype (MP)	abnormal cranium morphology	0.005909	--	Inherited
Mammalian Phenotype (MP)	abnormal CD4-positive, alpha beta T cell number	0.006842	--	Inherited
Mammalian Phenotype (MP)	abnormal hematopoietic system physiology	0.00726	--	Inherited
Mammalian Phenotype (MP)	abnormal kidney morphology	0.01452	--	Inherited
Mammalian Phenotype (MP)	abnormal skeleton morphology	0.01553	--	Inherited
Mammalian Phenotype (MP)	abnormal immune tolerance	0.01623	--	Inherited
Mammalian Phenotype (MP)	respiratory system inflammation	0.01762	--	Inherited
Mammalian Phenotype (MP)	skeleton phenotype	0.02183	--	Inherited
Mammalian Phenotype (MP)	abnormal immune system morphology	0.03252	--	Inherited
Mammalian Phenotype (MP)	integument phenotype	0.03689	--	Inherited
Mammalian Phenotype (MP)	abnormal immune cell physiology	0.04146	--	Inherited
Mammalian Phenotype (MP)	homeostasis/metabolism phenotype	0.04299	--	Inherited
Mammalian Phenotype (MP)	abnormal B cell physiology	0.04322	--	Inherited
Mammalian Phenotype (MP)	abnormal cell-mediated immunity	0.04425	--	Inherited
Mammalian Phenotype (MP)	abnormal hemopoiesis	0.04806	--	Inherited
Mammalian Phenotype (MP)	renal/urinary system phenotype	0.04809	--	Inherited
Mammalian Phenotype (MP)	abnormal adaptive immunity	0.05083	--	Inherited
Mammalian Phenotype (MP)	abnormal kidney cortex morphology	0.07178	--	Inherited
Mammalian Phenotype (MP)	abnormal craniofacial bone morphology	0.0827	--	Inherited
Mammalian Phenotype (MP)	increased alpha-beta T cell number	0.08666	--	Inherited
Mammalian Phenotype (MP)	abnormal lymph node cortex morphology	0.08819	--	Inherited
Mammalian Phenotype (MP)	abnormal hematopoietic cell number	0.09235	--	Inherited
Mammalian Phenotype (MP)	abnormal CD8-positive, alpha-beta T cell physiology	0.102	--	Inherited
Mammalian Phenotype (MP)	abnormal leukocyte cell number	0.1087	--	Inherited
Mammalian Phenotype (MP)	abnormal thymus lobule morphology	0.1091	--	Inherited
Mammalian Phenotype (MP)	abnormal leukopoiesis	0.11	--	Inherited
Mammalian Phenotype (MP)	vision/eye phenotype	0.111	--	Inherited
Mammalian Phenotype (MP)	abnormal nervous system physiology	0.1133	--	Inherited
Mammalian Phenotype (MP)	abnormal myeloid leukocyte morphology	0.1269	--	Inherited
Mammalian Phenotype (MP)	abnormal skeleton physiology	0.1574	--	Inherited
Mammalian Phenotype (MP)	abnormal interferon secretion	0.1574	--	Inherited
Mammalian Phenotype (MP)	abnormal lymphocyte morphology	0.1575	--	Inherited
Mammalian Phenotype (MP)	abnormal nephron morphology	0.1661	--	Inherited
Mammalian Phenotype (MP)	abnormal response to infection	0.1723	--	Inherited
Mammalian Phenotype (MP)	abnormal T cell activation	0.1763	--	Inherited
Mammalian Phenotype (MP)	abnormal respiratory system physiology	0.1839	--	Inherited
Mammalian Phenotype (MP)	abnormal lymph node size	0.2066	--	Inherited
Mammalian Phenotype (MP)	abnormal respiration	0.2425	--	Inherited
Mammalian Phenotype (MP)	abnormal IgG2 level	0.2501	--	Inherited
Mammalian Phenotype (MP)	abnormal hematopoietic system morphology/development	0.2524	--	Inherited
Mammalian Phenotype (MP)	abnormal lung morphology	0.3335	--	Inherited
Mammalian Phenotype (MP)	abnormal cytokine secretion	0.3353	--	Inherited
Mammalian Phenotype (MP)	abnormal lymphopoiesis	0.3453	--	Inherited
Mammalian Phenotype (MP)	increased autoantibody level	0.3779	--	Inherited
Mammalian Phenotype (MP)	decreased susceptibility to autoimmune disorder	0.4153	--	Inherited
Mammalian Phenotype (MP)	increased inflammatory response	0.4165	--	Inherited
Mammalian Phenotype (MP)	abnormal respiratory system morphology	0.4503	--	Inherited
Mammalian Phenotype (MP)	increased T cell number	0.4759	--	Inherited
Mammalian Phenotype (MP)	abnormal spleen size	0.5627	--	Inherited
Mammalian Phenotype (MP)	abnormal gland morphology	0.6242	--	Inherited
Mammalian Phenotype (MP)	abnormal T cell number	0.7118	--	Inherited
Mammalian Phenotype (MP)	abnormal IgG level	0.7664	--	Inherited
Mammalian Phenotype (MP)	abnormal effector T cell morphology	0.9637	--	Inherited
Mammalian Phenotype (MP)	abnormal alpha-beta T cell morphology	0.991	--	Inherited
Mammalian Phenotype (MP)	hematopoietic system phenotype	0.000002446	Least Informative	Direct
Mammalian Phenotype (MP)	immune system phenotype	0.000003257	Least Informative	Direct
Mammalian Phenotype (MP)	endocrine/exocrine gland phenotype	0.01048	Least Informative	Inherited
Mammalian Phenotype (MP)	abnormal homeostasis	0.3481	Least Informative	Inherited
Mammalian Phenotype (MP)	nervous system phenotype	0.5111	Least Informative	Inherited
Mammalian Phenotype (MP)	increased hematopoietic cell number	0.00000000591	Moderately Informative	Direct
Mammalian Phenotype (MP)	abnormal lymphocyte cell number	0.000000006679	Moderately Informative	Direct
Mammalian Phenotype (MP)	abnormal leukocyte physiology	0.00000004073	Moderately Informative	Direct
Mammalian Phenotype (MP)	abnormal bone structure	0.00007259	Moderately Informative	Direct
Mammalian Phenotype (MP)	altered susceptibility to infection	0.0005267	Moderately Informative	Direct
Mammalian Phenotype (MP)	abnormal craniofacial morphology	0.002491	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal immune serum protein physiology	0.002723	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal endocrine gland morphology	0.01426	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal renal/urinary system morphology	0.02	Moderately Informative	Inherited
Mammalian Phenotype (MP)	liver/biliary system phenotype	0.02	Moderately Informative	Inherited
Mammalian Phenotype (MP)	respiratory system phenotype	0.03479	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal protein level	0.05298	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal immune system organ morphology	0.06477	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal blood cell morphology/development	0.07029	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal eye morphology	0.08697	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal skin morphology	0.1589	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal professional antigen presenting cell physiology	0.2621	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal axial skeleton morphology	0.3064	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal blood cell morphology	0.3463	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal T cell morphology	0.6031	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal inflammatory response	0.6316	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal myeloid cell morphology	0.7851	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal interferon-gamma secretion	0.000011	Informative	Direct
Mammalian Phenotype (MP)	abnormal jaw morphology	0.0009907	Informative	Direct
Mammalian Phenotype (MP)	abnormal renal glomerulus morphology	0.002479	Informative	Inherited
Mammalian Phenotype (MP)	abnormal lymph node morphology	0.00649	Informative	Inherited
Mammalian Phenotype (MP)	abnormal thymus morphology	0.008982	Informative	Inherited
Mammalian Phenotype (MP)	increased lymphocyte cell number	0.009375	Informative	Inherited
Mammalian Phenotype (MP)	abnormal CD4-positive, alpha beta T cell morphology	0.01141	Informative	Inherited
Mammalian Phenotype (MP)	abnormal hepatobiliary system physiology	0.01399	Informative	Inherited
Mammalian Phenotype (MP)	abnormal immunoglobulin level	0.01754	Informative	Inherited
Mammalian Phenotype (MP)	abnormal spleen morphology	0.027	Informative	Inherited
Mammalian Phenotype (MP)	abnormal response to injury	0.0534	Informative	Inherited
Mammalian Phenotype (MP)	abnormal skin appearance	0.1329	Informative	Inherited
Mammalian Phenotype (MP)	altered susceptibility to bacterial infection	0.1423	Informative	Inherited
Mammalian Phenotype (MP)	altered susceptibility to autoimmune disorder	0.3365	Informative	Inherited
Mammalian Phenotype (MP)	abnormal T cell differentiation	0.3606	Informative	Inherited
Mammalian Phenotype (MP)	abnormal lymph organ size	0.3635	Informative	Inherited
Mammalian Phenotype (MP)	abnormal respiratory function	0.3865	Informative	Inherited
Mammalian Phenotype (MP)	increased susceptibility to infection	0.4634	Informative	Inherited
Mammalian Phenotype (MP)	abnormal T cell physiology	0.6126	Informative	Inherited
Mammalian Phenotype (MP)	abnormal alpha-beta T cell number	0.7315	Informative	Inherited
Mammalian Phenotype (MP)	abnormal spleen germinal center morphology	0.000000000000149	Highly Informative	Direct
Mammalian Phenotype (MP)	decreased acute inflammation	0.00000006578	Highly Informative	Direct
Mammalian Phenotype (MP)	decreased susceptibility to experimental autoimmune encephalomyelitis	0.00002355	Highly Informative	Direct
Mammalian Phenotype (MP)	abnormal IgG2b level	0.00002741	Highly Informative	Direct
Mammalian Phenotype (MP)	enlarged spleen	0.0000321	Highly Informative	Direct
Mammalian Phenotype (MP)	abnormal T cell proliferation	0.0000358	Highly Informative	Direct
Mammalian Phenotype (MP)	abnormal airway responsiveness	0.00004892	Highly Informative	Direct
Mammalian Phenotype (MP)	abnormal thymus medulla morphology	0.00007747	Highly Informative	Direct
Mammalian Phenotype (MP)	skin lesions	0.00008467	Highly Informative	Direct
Mammalian Phenotype (MP)	increased susceptibility to bacterial infection	0.0001357	Highly Informative	Direct
Mammalian Phenotype (MP)	abnormal cytotoxic T cell physiology	0.0003016	Highly Informative	Direct
Mammalian Phenotype (MP)	abnormal body temperature homeostasis	0.0003232	Highly Informative	Direct
Mammalian Phenotype (MP)	altered response to CNS ischemic injury	0.0004643	Highly Informative	Direct
Mammalian Phenotype (MP)	enlarged lymph nodes	0.000479	Highly Informative	Direct
Mammalian Phenotype (MP)	lung inflammation	0.000597	Highly Informative	Direct
Mammalian Phenotype (MP)	abnormal myelination	0.0006132	Highly Informative	Direct
Mammalian Phenotype (MP)	abnormal thymus size	0.616	Highly Informative	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

ZA

Zebrafish Anatomy (ZA)

	ZA term	FDR (all)	SDZA (four levels)	Annotation (direct or inherited)
Zebrafish Anatomy (ZA)	whole organism	0	--	Direct
Zebrafish Anatomy (ZA)	anatomical group	0	--	Direct
Zebrafish Anatomy (ZA)	anatomical structure	1	--	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

XA

Xenopus Anatomy (XA)

	XA term	FDR (all)	SDXA (four levels)	Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)	head region	0	--	Direct
Xenopus ANatomical entity (XAN)	trunk region	0	--	Direct
Xenopus ANatomical entity (XAN)	central nervous system	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical structure	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical group	0	--	Direct
Xenopus ANatomical entity (XAN)	organism subdivision	0	--	Direct
Xenopus ANatomical entity (XAN)	compound organ	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical region	0	--	Direct
Xenopus ANatomical entity (XAN)	multicellular anatomical structure	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical system	1	--	Inherited
Xenopus ANatomical entity (XAN)	whole organism	1	--	Inherited
Xenopus ANatomical entity (XAN)	nervous system	0	Least Informative	Direct
Xenopus ANatomical entity (XAN)	head	0	Least Informative	Direct
Xenopus ANatomical entity (XAN)	trunk	0	Least Informative	Direct
Xenopus ANatomical entity (XAN)	cavitated compound organ	0	Least Informative	Direct

	XA term	FDR (all)	SDXA (four levels)	Annotation (direct or inherited)
Xenopus DEvelopment stage (XDE)	NF stage	0	--	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

CD

CTD Diseases (CD)

	CD term	FDR (all)	SDCD (four levels)	Annotation (direct or inherited)
CTD Diseases (CD)	Immune System Diseases	0.0000008805	Moderately Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

CC

CTD Chemicals (CC)

	CC term	FDR (all)	SDCC (four levels)	Annotation (direct or inherited)
CTD Chemicals (CC)	Heterocyclic Compounds, Fused-Ring	0	--	Direct
CTD Chemicals (CC)	Hexanols	0	--	Direct
CTD Chemicals (CC)	Carboxylic Acids	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds, 1-Ring	0	--	Direct
CTD Chemicals (CC)	Hydrocarbons	0	--	Direct
CTD Chemicals (CC)	Hydrocarbons, Aromatic	0	--	Direct
CTD Chemicals (CC)	Hydrocarbons, Cyclic	0	--	Direct
CTD Chemicals (CC)	Inorganic Chemicals	0	--	Direct
CTD Chemicals (CC)	Menthol	0	--	Direct
CTD Chemicals (CC)	Organic Chemicals	0	--	Direct
CTD Chemicals (CC)	Polycyclic Compounds	0	--	Direct
CTD Chemicals (CC)	Fatty Alcohols	0.000000000000001158	--	Direct
CTD Chemicals (CC)	butylphen	0.00000000002888	--	Direct
CTD Chemicals (CC)	Fluorine Compounds	0.000000008001	--	Direct
CTD Chemicals (CC)	Hydrofluoric Acid	0.00000003716	--	Direct
CTD Chemicals (CC)	2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyc	0.00000004049	--	Direct
CTD Chemicals (CC)	alpha-Chlorohydrin	0.00000004066	--	Direct
CTD Chemicals (CC)	4-(3-(1-adamantyl)-4-hydroxyphenyl)-3-chlorocinnamic acid	0.00000004556	--	Direct
CTD Chemicals (CC)	Amidines	0.0000001188	--	Direct
CTD Chemicals (CC)	dioscin	0.0000001955	--	Direct
CTD Chemicals (CC)	Melitten	0.0000004953	--	Direct
CTD Chemicals (CC)	Pyridinium Compounds	0.0000005049	--	Direct
CTD Chemicals (CC)	HhAntag691	0.0000008046	--	Direct
CTD Chemicals (CC)	Magnesium Oxide	0.000001042	--	Direct
CTD Chemicals (CC)	Nystatin	0.000002095	--	Direct
CTD Chemicals (CC)	Heptanes	0.000002315	--	Direct
CTD Chemicals (CC)	aloe emodin	0.000002862	--	Direct
CTD Chemicals (CC)	Metformin	0.000003946	--	Direct
CTD Chemicals (CC)	Pentoxifylline	0.000004035	--	Direct
CTD Chemicals (CC)	Hydrocarbons, Alicyclic	0.00000636	--	Direct
CTD Chemicals (CC)	Epoxy Compounds	0.0000121	--	Direct
CTD Chemicals (CC)	Nonidet P-40	0.00001242	--	Direct
CTD Chemicals (CC)	Paclitaxel	0.00001323	--	Direct
CTD Chemicals (CC)	licochalcone A	0.00001455	--	Direct
CTD Chemicals (CC)	Quinolines	0.00001713	--	Direct
CTD Chemicals (CC)	Theobromine	0.00001785	--	Direct
CTD Chemicals (CC)	Isoindoles	0.00001842	--	Direct
CTD Chemicals (CC)	2-(3'-methoxyphenyl)-6-pyrrolidinyl-4-quinazolinone	0.00003165	--	Direct
CTD Chemicals (CC)	Spirostans	0.00003426	--	Direct
CTD Chemicals (CC)	fludarabine	0.00003518	--	Direct
CTD Chemicals (CC)	Hydroxybenzoates	0.00005036	--	Direct
CTD Chemicals (CC)	Polyunsaturated Alkamides	0.00005181	--	Direct
CTD Chemicals (CC)	Ozone	0.00007296	--	Direct
CTD Chemicals (CC)	Polybrominated Biphenyls	0.0000778	--	Direct
CTD Chemicals (CC)	3,4,5,4'-tetramethoxystilbene	0.00009109	--	Direct
CTD Chemicals (CC)	Antigens	0.00009671	--	Direct
CTD Chemicals (CC)	Benzophenones	0.00009697	--	Direct
CTD Chemicals (CC)	Isobutyrates	0.00009969	--	Direct
CTD Chemicals (CC)	Titanium	0.0001303	--	Direct
CTD Chemicals (CC)	Polysaccharides	0.0001326	--	Direct
CTD Chemicals (CC)	Fluorouracil	0.0001881	--	Direct
CTD Chemicals (CC)	Stilbenes	0.0001947	--	Direct
CTD Chemicals (CC)	sanguinarine	0.0002146	--	Direct
CTD Chemicals (CC)	Flavones	0.0002842	--	Direct
CTD Chemicals (CC)	Vidarabine	0.000427	--	Direct
CTD Chemicals (CC)	Chlorambucil	0.0004446	--	Direct
CTD Chemicals (CC)	Pterins	0.0005406	--	Direct
CTD Chemicals (CC)	Aniline Compounds	0.0006254	--	Direct
CTD Chemicals (CC)	Glycoconjugates	0.0007	--	Direct
CTD Chemicals (CC)	mercuric bromide	0.0008834	--	Direct
CTD Chemicals (CC)	Aspirin	0.0009338	--	Direct
CTD Chemicals (CC)	Phenylpropionates	0.0009385	--	Direct
CTD Chemicals (CC)	Chromones	0.00118	--	Inherited
CTD Chemicals (CC)	Phenanthridines	0.002091	--	Inherited
CTD Chemicals (CC)	Deoxycytidine	0.002377	--	Inherited
CTD Chemicals (CC)	Hydrocarbons, Acyclic	0.002623	--	Inherited
CTD Chemicals (CC)	Cycloparaffins	0.002695	--	Inherited
CTD Chemicals (CC)	Butyrates	0.002859	--	Inherited
CTD Chemicals (CC)	Bromides	0.003586	--	Inherited
CTD Chemicals (CC)	Hydrobromic Acid	0.004845	--	Inherited
CTD Chemicals (CC)	Bacterial Toxins	0.007522	--	Inherited
CTD Chemicals (CC)	Polyketides	0.007913	--	Inherited
CTD Chemicals (CC)	Taxoids	0.008534	--	Inherited
CTD Chemicals (CC)	Metalloids	0.00905	--	Inherited
CTD Chemicals (CC)	Endotoxins	0.0117	--	Inherited
CTD Chemicals (CC)	Arthropod Venoms	0.01224	--	Inherited
CTD Chemicals (CC)	Sulfonamides	0.01555	--	Inherited
CTD Chemicals (CC)	Oxygen Compounds	0.01597	--	Inherited
CTD Chemicals (CC)	Flavonols	0.03611	--	Inherited
CTD Chemicals (CC)	Quinones	0.0368	--	Inherited
CTD Chemicals (CC)	Pyrimidinones	0.04264	--	Inherited
CTD Chemicals (CC)	Cholestanes	0.05093	--	Inherited
CTD Chemicals (CC)	Lipids	0.05195	--	Inherited
CTD Chemicals (CC)	Octoxynol	0.05334	--	Inherited
CTD Chemicals (CC)	Glycosides	0.06225	--	Inherited
CTD Chemicals (CC)	Peptides	0.07843	--	Inherited
CTD Chemicals (CC)	Fatty Acids, Volatile	0.09128	--	Inherited
CTD Chemicals (CC)	Ribonucleosides	0.09598	--	Inherited
CTD Chemicals (CC)	Pyrimidine Nucleosides	0.1209	--	Inherited
CTD Chemicals (CC)	Toxins, Biological	0.1659	--	Inherited
CTD Chemicals (CC)	Biguanides	0.1661	--	Inherited
CTD Chemicals (CC)	Phenyl Ethers	0.202	--	Inherited
CTD Chemicals (CC)	Alkenes	0.2244	--	Inherited
CTD Chemicals (CC)	Propiophenones	0.2828	--	Inherited
CTD Chemicals (CC)	Nitrogen Mustard Compounds	0.3271	--	Inherited
CTD Chemicals (CC)	Antigens, Bacterial	0.3454	--	Inherited
CTD Chemicals (CC)	Ethylene Glycols	0.3663	--	Inherited
CTD Chemicals (CC)	Polysaccharides, Bacterial	0.3786	--	Inherited
CTD Chemicals (CC)	Nucleic Acids, Nucleotides, and Nucleosides	0.3997	--	Inherited
CTD Chemicals (CC)	Acids, Acyclic	0.4026	--	Inherited
CTD Chemicals (CC)	Pyrans	0.4029	--	Inherited
CTD Chemicals (CC)	Transition Elements	0.506	--	Inherited
CTD Chemicals (CC)	Benzene Derivatives	0.6102	--	Inherited
CTD Chemicals (CC)	Fatty Acids	0.6302	--	Inherited
CTD Chemicals (CC)	Heterocyclic Compounds, 2-Ring	0.915	--	Inherited
CTD Chemicals (CC)	Acids, Noncarboxylic	1	--	Inherited
CTD Chemicals (CC)	Anions	1	--	Inherited
CTD Chemicals (CC)	Ions	1	--	Inherited
CTD Chemicals (CC)	Steroids	1	--	Inherited
CTD Chemicals (CC)	Electrolytes	0	Least Informative	Direct
CTD Chemicals (CC)	Polycyclic Aromatic Hydrocarbons	0	Least Informative	Direct
CTD Chemicals (CC)	Macrocyclic Compounds	0	Least Informative	Direct
CTD Chemicals (CC)	Terpenes	0.00005742	Least Informative	Direct
CTD Chemicals (CC)	Fused-Ring Compounds	0.005532	Least Informative	Inherited
CTD Chemicals (CC)	Phenols	0.01013	Least Informative	Inherited
CTD Chemicals (CC)	Elements	0.01241	Least Informative	Inherited
CTD Chemicals (CC)	Azoles	0.01505	Least Informative	Inherited
CTD Chemicals (CC)	Acids	0.0417	Least Informative	Inherited
CTD Chemicals (CC)	Complex Mixtures	0.04176	Least Informative	Inherited
CTD Chemicals (CC)	Amides	0.05754	Least Informative	Inherited
CTD Chemicals (CC)	Sulfur Compounds	0.08777	Least Informative	Inherited
CTD Chemicals (CC)	Amines	0.08812	Least Informative	Inherited
CTD Chemicals (CC)	Carbohydrates	0.09528	Least Informative	Inherited
CTD Chemicals (CC)	Acids, Carbocyclic	0.1012	Least Informative	Inherited
CTD Chemicals (CC)	Amino Acids, Peptides, and Proteins	0.1166	Least Informative	Inherited
CTD Chemicals (CC)	Biological Factors	0.1565	Least Informative	Inherited
CTD Chemicals (CC)	Metals	0.2231	Least Informative	Inherited
CTD Chemicals (CC)	Benzopyrans	0.2837	Least Informative	Inherited
CTD Chemicals (CC)	Indoles	0.3153	Least Informative	Inherited
CTD Chemicals (CC)	Pyrimidines	0.6065	Least Informative	Inherited
CTD Chemicals (CC)	Monoterpenes	0.000000000000001158	Moderately Informative	Direct
CTD Chemicals (CC)	Alcohols	0.0000000002184	Moderately Informative	Direct
CTD Chemicals (CC)	Cyclohexanes	0.00000005137	Moderately Informative	Direct
CTD Chemicals (CC)	Catechols	0.0000003158	Moderately Informative	Direct
CTD Chemicals (CC)	Arsenicals	0.0000005502	Moderately Informative	Direct
CTD Chemicals (CC)	Gases	0.000001888	Moderately Informative	Direct
CTD Chemicals (CC)	Piperidines	0.000007564	Moderately Informative	Direct
CTD Chemicals (CC)	Fatty Acids, Unsaturated	0.00002142	Moderately Informative	Direct
CTD Chemicals (CC)	Imidazoles	0.0000244	Moderately Informative	Direct
CTD Chemicals (CC)	Biphenyl Compounds	0.0000943	Moderately Informative	Direct
CTD Chemicals (CC)	Anilides	0.0004166	Moderately Informative	Direct
CTD Chemicals (CC)	Benzylidene Compounds	0.000522	Moderately Informative	Direct
CTD Chemicals (CC)	Hydrocarbons, Halogenated	0.0007176	Moderately Informative	Direct
CTD Chemicals (CC)	Flavonoids	0.001126	Moderately Informative	Inherited
CTD Chemicals (CC)	Pyridines	0.003049	Moderately Informative	Inherited
CTD Chemicals (CC)	Organophosphorus Compounds	0.003348	Moderately Informative	Inherited
CTD Chemicals (CC)	Heterocyclic Compounds, 3-Ring	0.00724	Moderately Informative	Inherited
CTD Chemicals (CC)	Ethers	0.01655	Moderately Informative	Inherited
CTD Chemicals (CC)	Pigments, Biological	0.02411	Moderately Informative	Inherited
CTD Chemicals (CC)	Lactones	0.02541	Moderately Informative	Inherited
CTD Chemicals (CC)	Heterocyclic Compounds, 4 or More Rings	0.03115	Moderately Informative	Inherited
CTD Chemicals (CC)	Benzoates	0.03939	Moderately Informative	Inherited
CTD Chemicals (CC)	Pyrazoles	0.05553	Moderately Informative	Inherited
CTD Chemicals (CC)	Alkanes	0.08372	Moderately Informative	Inherited
CTD Chemicals (CC)	Alkaloids	0.08978	Moderately Informative	Inherited
CTD Chemicals (CC)	Hydroxy Acids	0.09987	Moderately Informative	Inherited
CTD Chemicals (CC)	Diterpenes	0.1121	Moderately Informative	Inherited
CTD Chemicals (CC)	Oxides	0.1155	Moderately Informative	Inherited
CTD Chemicals (CC)	Sulfones	0.1173	Moderately Informative	Inherited
CTD Chemicals (CC)	Sesquiterpenes	0.226	Moderately Informative	Inherited
CTD Chemicals (CC)	Purines	0.3131	Moderately Informative	Inherited
CTD Chemicals (CC)	Nucleosides	0.5918	Moderately Informative	Inherited
CTD Chemicals (CC)	Biological Products	0.7309	Moderately Informative	Inherited
CTD Chemicals (CC)	Polyenes	0.9341	Moderately Informative	Inherited
CTD Chemicals (CC)	Cyclohexane Monoterpenes	0	Informative	Direct
CTD Chemicals (CC)	Cyclohexanols	0	Informative	Direct
CTD Chemicals (CC)	Silver Compounds	0.0000000008498	Informative	Direct
CTD Chemicals (CC)	Diarylheptanoids	0.00000001329	Informative	Direct
CTD Chemicals (CC)	Guanidines	0.00000004767	Informative	Direct
CTD Chemicals (CC)	Organophosphonates	0.0000008548	Informative	Direct
CTD Chemicals (CC)	Arsenic Trioxide	0.000001199	Informative	Direct
CTD Chemicals (CC)	Stilbestrols	0.000002117	Informative	Direct
CTD Chemicals (CC)	Hydrocarbons, Brominated	0.00001175	Informative	Direct
CTD Chemicals (CC)	Pteridines	0.00002264	Informative	Direct
CTD Chemicals (CC)	Amino Sugars	0.00002544	Informative	Direct
CTD Chemicals (CC)	Venoms	0.00003385	Informative	Direct
CTD Chemicals (CC)	Piperazines	0.00004159	Informative	Direct
CTD Chemicals (CC)	Azepines	0.00004807	Informative	Direct
CTD Chemicals (CC)	Imides	0.0001323	Informative	Direct
CTD Chemicals (CC)	Pyrrolidines	0.0001485	Informative	Direct
CTD Chemicals (CC)	Solanaceous Alkaloids	0.0001854	Informative	Direct
CTD Chemicals (CC)	Lipopolysaccharides	0.0002081	Informative	Direct
CTD Chemicals (CC)	Polyphenols	0.0002149	Informative	Direct
CTD Chemicals (CC)	Imines	0.0002423	Informative	Direct
CTD Chemicals (CC)	Quinolones	0.0002591	Informative	Direct
CTD Chemicals (CC)	Quercetin	0.0003314	Informative	Direct
CTD Chemicals (CC)	Alkynes	0.0004495	Informative	Direct
CTD Chemicals (CC)	Nitroso Compounds	0.0004625	Informative	Direct
CTD Chemicals (CC)	Ketones	0.0005328	Informative	Direct
CTD Chemicals (CC)	Quinazolines	0.0007539	Informative	Direct
CTD Chemicals (CC)	Isocyanates	0.0007984	Informative	Direct
CTD Chemicals (CC)	Thiophenes	0.0009309	Informative	Direct
CTD Chemicals (CC)	Fibric Acids	0.001117	Informative	Inherited
CTD Chemicals (CC)	Chalcogens	0.001188	Informative	Inherited
CTD Chemicals (CC)	Metals, Light	0.001347	Informative	Inherited
CTD Chemicals (CC)	Bridged-Ring Compounds	0.001787	Informative	Inherited
CTD Chemicals (CC)	Purine Nucleosides	0.002658	Informative	Inherited
CTD Chemicals (CC)	Ethers, Cyclic	0.005516	Informative	Inherited
CTD Chemicals (CC)	Cyclodecanes	0.006251	Informative	Inherited
CTD Chemicals (CC)	Glycols	0.006282	Informative	Inherited
CTD Chemicals (CC)	Uracil	0.007479	Informative	Inherited
CTD Chemicals (CC)	Isoquinolines	0.0107	Informative	Inherited
CTD Chemicals (CC)	Macrolides	0.01136	Informative	Inherited
CTD Chemicals (CC)	Anthracenes	0.01743	Informative	Inherited
CTD Chemicals (CC)	Deoxyribonucleosides	0.01897	Informative	Inherited
CTD Chemicals (CC)	Coumarins	0.03661	Informative	Inherited
CTD Chemicals (CC)	Piperidones	0.04268	Informative	Inherited
CTD Chemicals (CC)	Halogenated Diphenyl Ethers	0.05073	Informative	Inherited
CTD Chemicals (CC)	Mustard Compounds	0.09086	Informative	Inherited
CTD Chemicals (CC)	Cinnamates	0.1104	Informative	Inherited
CTD Chemicals (CC)	Purinones	0.1134	Informative	Inherited
CTD Chemicals (CC)	Cytidine	0.3167	Informative	Inherited
CTD Chemicals (CC)	Isoflavones	0.446	Informative	Inherited
CTD Chemicals (CC)	Salicylates	0.9484	Informative	Inherited
CTD Chemicals (CC)	5-OH-BDE-47	0.0000000000009247	Highly Informative	Direct
CTD Chemicals (CC)	Vemurafenib	0.000000000002304	Highly Informative	Direct
CTD Chemicals (CC)	osthol	0.000000003295	Highly Informative	Direct
CTD Chemicals (CC)	Fluorides	0.00000002652	Highly Informative	Direct
CTD Chemicals (CC)	2-anisidine	0.00000005542	Highly Informative	Direct
CTD Chemicals (CC)	Diosgenin	0.0000004953	Highly Informative	Direct
CTD Chemicals (CC)	Bee Venoms	0.0000008016	Highly Informative	Direct
CTD Chemicals (CC)	Celecoxib	0.00000127	Highly Informative	Direct
CTD Chemicals (CC)	Polyethylenes	0.000001933	Highly Informative	Direct
CTD Chemicals (CC)	Antimicrobial Cationic Peptides	0.000005908	Highly Informative	Direct
CTD Chemicals (CC)	Polyethylene Glycols	0.00001147	Highly Informative	Direct
CTD Chemicals (CC)	Fenofibrate	0.00002648	Highly Informative	Direct
CTD Chemicals (CC)	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole	0.00004011	Highly Informative	Direct
CTD Chemicals (CC)	Genistein	0.00007051	Highly Informative	Direct
CTD Chemicals (CC)	Ibuprofen	0.0001264	Highly Informative	Direct
CTD Chemicals (CC)	3,5-bis(2-fluorobenzylidene)piperidin-4-one	0.0001409	Highly Informative	Direct
CTD Chemicals (CC)	Paraquat	0.0001581	Highly Informative	Direct
CTD Chemicals (CC)	Chlorohydrins	0.0001656	Highly Informative	Direct
CTD Chemicals (CC)	Parabens	0.0001926	Highly Informative	Direct
CTD Chemicals (CC)	Plant Exudates	0.0001982	Highly Informative	Direct
CTD Chemicals (CC)	gemcitabine	0.0002317	Highly Informative	Direct
CTD Chemicals (CC)	2,2',4,4'-tetrabromodiphenyl ether	0.0002544	Highly Informative	Direct
CTD Chemicals (CC)	Benzophenanthridines	0.0002548	Highly Informative	Direct
CTD Chemicals (CC)	Arsenic	0.0004579	Highly Informative	Direct
CTD Chemicals (CC)	Aripiprazole	0.0004634	Highly Informative	Direct
CTD Chemicals (CC)	Oxygen	0.000577	Highly Informative	Direct
CTD Chemicals (CC)	Bromine Compounds	0.0019	Highly Informative	Inherited
CTD Chemicals (CC)	Mercury Compounds	0.003586	Highly Informative	Inherited
CTD Chemicals (CC)	Chalcones	0.003596	Highly Informative	Inherited
CTD Chemicals (CC)	Adenosine	0.009267	Highly Informative	Inherited
CTD Chemicals (CC)	Quinazolinones	0.02541	Highly Informative	Inherited
CTD Chemicals (CC)	Magnesium Compounds	0.03426	Highly Informative	Inherited
CTD Chemicals (CC)	Adamantane	0.03668	Highly Informative	Inherited
CTD Chemicals (CC)	Arabinonucleosides	0.04714	Highly Informative	Inherited
CTD Chemicals (CC)	Anthraquinones	0.06197	Highly Informative	Inherited
CTD Chemicals (CC)	Propylene Glycols	0.07	Highly Informative	Inherited
CTD Chemicals (CC)	Xanthines	0.2837	Highly Informative	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

Distribution on sTOL

Plot distribution on species Tree Of Life (sTOL) for this domain, i.e., present or absent across genomes/tips

Plot tree as:

Download Newick format tree:

Browsing in TREE OF LIFE:

(show help)

LINKOUT

TNF receptor-like family