SNARE fusion complex superfamily

DO

Disease Ontology (DO)

	DO term	FDR (all)	SDDO (four levels)	Annotation (direct or inherited)
Disease Ontology (DO)	parathyroid adenoma	0.000000003575	--	Direct
Disease Ontology (DO)	disease of cellular proliferation	1	--	Inherited
Disease Ontology (DO)	benign neoplasm	0.0422	Moderately Informative	Inherited
Disease Ontology (DO)	organ system benign neoplasm	0.002863	Informative	Inherited
Disease Ontology (DO)	endocrine organ benign neoplasm	0.00009375	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

HP

Human Phenotype (HP)

	HP term	FDR (all)	SDHP (four levels)	Annotation (direct or inherited)
Phenotypic Abnormality (PA)	Abnormality of the nervous system	0	--	Direct
Phenotypic Abnormality (PA)	Abnormality of the skeletal system	0	--	Direct
Phenotypic Abnormality (PA)	Abnormal axial skeleton morphology	0	--	Direct
Phenotypic Abnormality (PA)	Abnormal muscle physiology	0	--	Direct
Phenotypic Abnormality (PA)	EEG with spike-wave complexes	0.00000926	--	Direct
Phenotypic Abnormality (PA)	Poor head control	0.0001769	--	Direct
Phenotypic Abnormality (PA)	Long face	0.0002817	--	Direct
Phenotypic Abnormality (PA)	Prenatal movement abnormality	0.0003706	--	Direct
Phenotypic Abnormality (PA)	Reduced tendon reflexes	0.0003759	--	Direct
Phenotypic Abnormality (PA)	EEG with generalized epileptiform discharges	0.000497	--	Direct
Phenotypic Abnormality (PA)	Hip dislocation	0.0005754	--	Direct
Phenotypic Abnormality (PA)	Interictal EEG abnormality	0.0006111	--	Direct
Phenotypic Abnormality (PA)	Lower extremity joint dislocation	0.000969	--	Direct
Phenotypic Abnormality (PA)	Abnormality of the hip joint	0.001203	--	Inherited
Phenotypic Abnormality (PA)	EEG abnormality	0.004364	--	Inherited
Phenotypic Abnormality (PA)	Abnormality of the hip bone	0.004364	--	Inherited
Phenotypic Abnormality (PA)	Large face	0.01963	--	Inherited
Phenotypic Abnormality (PA)	Abnormality of the face	0.1564	--	Inherited
Phenotypic Abnormality (PA)	Abnormality of head or neck	0.2145	--	Inherited
Phenotypic Abnormality (PA)	Muscle weakness	0.2296	--	Inherited
Phenotypic Abnormality (PA)	Abnormal appendicular skeleton morphology	0.4234	--	Inherited
Phenotypic Abnormality (PA)	Abnormality of central nervous system electrophysiology	0.6334	--	Inherited
Phenotypic Abnormality (PA)	Interictal epileptiform activity	1	--	Inherited
Phenotypic Abnormality (PA)	Abnormality of the musculature	0	Least Informative	Direct
Phenotypic Abnormality (PA)	Abnormality of skeletal morphology	0	Least Informative	Direct
Phenotypic Abnormality (PA)	Abnormality of nervous system physiology	0	Least Informative	Direct
Phenotypic Abnormality (PA)	Abnormality of the head	0.2095	Least Informative	Inherited
Phenotypic Abnormality (PA)	Abnormality of limbs	0.229	Least Informative	Inherited
Phenotypic Abnormality (PA)	Abnormality of higher mental function	0	Moderately Informative	Direct
Phenotypic Abnormality (PA)	Abnormality of movement	0	Moderately Informative	Direct
Phenotypic Abnormality (PA)	Abnormality of the lower limb	0.1109	Moderately Informative	Inherited
Phenotypic Abnormality (PA)	Abnormal joint morphology	0.1812	Moderately Informative	Inherited
Phenotypic Abnormality (PA)	Seizures	0	Informative	Direct
Phenotypic Abnormality (PA)	Abnormality of the synovia	0.001333	Informative	Inherited
Phenotypic Abnormality (PA)	Abnormal nervous system electrophysiology	0.002077	Informative	Inherited
Phenotypic Abnormality (PA)	Joint dislocation	0.00249	Informative	Inherited
Phenotypic Abnormality (PA)	Abnormal facial shape	0.004291	Informative	Inherited
Phenotypic Abnormality (PA)	Abnormality of pelvic girdle bone morphology	0.007172	Informative	Inherited
Phenotypic Abnormality (PA)	Abnormality of lower limb joint	0.009124	Informative	Inherited
Phenotypic Abnormality (PA)	Abnormality of prenatal development or birth	0.02377	Informative	Inherited
Phenotypic Abnormality (PA)	Neurological speech impairment	0.07819	Informative	Inherited
Phenotypic Abnormality (PA)	Abnormal reflex	0.1842	Informative	Inherited
Phenotypic Abnormality (PA)	Areflexia	0.00001345	Highly Informative	Direct
Phenotypic Abnormality (PA)	Decreased fetal movement	0.0002887	Highly Informative	Direct
Phenotypic Abnormality (PA)	Dysarthria	0.0004026	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

MP

Mouse Phenotype (MP)

	MP term	FDR (all)	SDMP (four levels)	Annotation (direct or inherited)
Mammalian Phenotype (MP)	abnormal neurotransmitter secretion	0.00007651	--	Direct
Mammalian Phenotype (MP)	abnormal axon extension	0.0004687	--	Direct
Mammalian Phenotype (MP)	abnormal paired-pulse facilitation	0.01147	--	Inherited
Mammalian Phenotype (MP)	abnormal neuron differentiation	0.03896	--	Inherited
Mammalian Phenotype (MP)	abnormal synaptic transmission	0.04399	--	Inherited
Mammalian Phenotype (MP)	abnormal cell physiology	0.7653	--	Inherited
Mammalian Phenotype (MP)	abnormal nervous system morphology	0.8869	--	Inherited
Mammalian Phenotype (MP)	nervous system phenotype	0.1911	Least Informative	Inherited
Mammalian Phenotype (MP)	cellular phenotype	0.8686	Least Informative	Inherited
Mammalian Phenotype (MP)	abnormal nervous system physiology	0.04937	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal neuron morphology	0.3801	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal nervous system development	0.4498	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal cell differentiation	0.06472	Informative	Inherited
Mammalian Phenotype (MP)	enhanced paired-pulse facilitation	0.00006378	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

WP

Worm Phenotype (WP)

	WP term	FDR (all)	SDWP (four levels)	Annotation (direct or inherited)
Worm Phenotype (WP)	lethal	0	--	Direct
Worm Phenotype (WP)	fertility variant	0	--	Direct
Worm Phenotype (WP)	development variant	0	--	Direct
Worm Phenotype (WP)	morphology variant	0	--	Direct
Worm Phenotype (WP)	organism development variant	0	--	Direct
Worm Phenotype (WP)	organ system physiology variant	0	--	Direct
Worm Phenotype (WP)	reproductive system physiology variant	0	--	Direct
Worm Phenotype (WP)	fertility reduced	0	--	Direct
Worm Phenotype (WP)	lysosome morphology variant	0.00000000000348	--	Direct
Worm Phenotype (WP)	cell component morphology variant	0.2446	--	Inherited
Worm Phenotype (WP)	physiology variant	1	--	Inherited
Worm Phenotype (WP)	cell morphology variant	0.0004585	Least Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

FP

Fly Phenotype (FP)

	FP term	FDR (all)	SDFP (four levels)	Annotation (direct or inherited)
Fly Phenotype (FP)	uncoordinated	0.000418	--	Direct
Fly Phenotype (FP)	increased mortality during development	0.0009431	--	Direct
Fly Phenotype (FP)	phenotype	0.1555	--	Inherited
Fly Phenotype (FP)	increased mortality	0.003864	Least Informative	Inherited
Fly Phenotype (FP)	behavior defective	0.4601	Moderately Informative	Inherited
Fly Phenotype (FP)	neurophysiology defective	0.0006937	Informative	Direct
Fly Phenotype (FP)	locomotor behavior defective	0.1743	Highly Informative	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

FA

Fly Anatomy (FA)

	FA term	FDR (all)	SDFA (four levels)	Annotation (direct or inherited)
Fly Anatomy (FA)	organism	0	--	Direct
Fly Anatomy (FA)	multicellular structure	0	--	Direct
Fly Anatomy (FA)	anatomical structure	1	--	Inherited
Fly Anatomy (FA)	material anatomical entity	1	--	Inherited
Fly Anatomy (FA)	larva	0	Least Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

ZA

Zebrafish Anatomy (ZA)

	ZA term	FDR (all)	SDZA (four levels)	Annotation (direct or inherited)
Zebrafish Anatomy (ZA)	brain	0	--	Direct
Zebrafish Anatomy (ZA)	hindbrain	0	--	Direct
Zebrafish Anatomy (ZA)	whole organism	0	--	Direct
Zebrafish Anatomy (ZA)	anatomical system	0	--	Direct
Zebrafish Anatomy (ZA)	cavitated compound organ	0	--	Direct
Zebrafish Anatomy (ZA)	anatomical group	0	--	Direct
Zebrafish Anatomy (ZA)	anatomical structure	1	--	Inherited
Zebrafish Anatomy (ZA)	nervous system	0	Least Informative	Direct
Zebrafish Anatomy (ZA)	compound organ	0	Least Informative	Direct
Zebrafish Anatomy (ZA)	multi-tissue structure	0	Least Informative	Direct
Zebrafish Anatomy (ZA)	central nervous system	0	Moderately Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

XA

Xenopus Anatomy (XA)

	XA term	FDR (all)	SDXA (four levels)	Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)	anatomical structure	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical group	0	--	Direct
Xenopus ANatomical entity (XAN)	multicellular anatomical structure	0	--	Direct
Xenopus ANatomical entity (XAN)	whole organism	1	--	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

AP

Arabidopsis Plant Ontology (AP)

	AP term	FDR (all)	SDAP (four levels)	Annotation (direct or inherited)
Plant ANatomical entity (PAN)	plant cell	0.0646	--	Inherited
Plant ANatomical entity (PAN)	plant structure	1	--	Inherited
Plant ANatomical entity (PAN)	pollen tube cell	0.0000001036	Informative	Direct

	AP term	FDR (all)	SDAP (four levels)	Annotation (direct or inherited)
Plant structure DEvelopment stage (PDE)	floral organ differentiation stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	collective plant organ structure development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	plant organ development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	reproductive shoot system development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	collective phyllome structure development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	floral organ formation stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	androecium development stage	0.000005469	--	Direct
Plant structure DEvelopment stage (PDE)	flower development stage	1	--	Inherited
Plant structure DEvelopment stage (PDE)	shoot system development stage	1	--	Inherited
Plant structure DEvelopment stage (PDE)	pollen development stage	0.00000189	Moderately Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

CD

CTD Diseases (CD)

	CD term	FDR (all)	SDCD (four levels)	Annotation (direct or inherited)
CTD Diseases (CD)	Psychotic Disorders	0.000008134	--	Direct
CTD Diseases (CD)	Bipolar and Related Disorders	0.0001824	--	Direct
CTD Diseases (CD)	Mental Disorders	0.1231	Moderately Informative	Inherited
CTD Diseases (CD)	Schizophrenia Spectrum and Other Psychotic Disorders	0.003315	Highly Informative	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

CC

CTD Chemicals (CC)

	CC term	FDR (all)	SDCC (four levels)	Annotation (direct or inherited)
CTD Chemicals (CC)	Heterocyclic Compounds	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds, 1-Ring	0	--	Direct
CTD Chemicals (CC)	Hydrocarbons	0	--	Direct
CTD Chemicals (CC)	Inorganic Chemicals	0	--	Direct
CTD Chemicals (CC)	Organic Chemicals	0	--	Direct
CTD Chemicals (CC)	Heroin	0.000005503	--	Direct
CTD Chemicals (CC)	Lactic Acid	0.0003004	--	Direct
CTD Chemicals (CC)	Morphinans	0.0004946	--	Direct
CTD Chemicals (CC)	Opiate Alkaloids	0.00123	--	Inherited
CTD Chemicals (CC)	Hydrocarbons, Aromatic	0.08104	--	Inherited
CTD Chemicals (CC)	Polycyclic Compounds	0.08435	--	Inherited
CTD Chemicals (CC)	Carboxylic Acids	0.1721	--	Inherited
CTD Chemicals (CC)	Heterocyclic Compounds, Bridged-Ring	0.3419	--	Inherited
CTD Chemicals (CC)	Heterocyclic Compounds, Fused-Ring	0.55	--	Inherited
CTD Chemicals (CC)	Hydrocarbons, Cyclic	0.8362	--	Inherited
CTD Chemicals (CC)	Polycyclic Aromatic Hydrocarbons	0.7159	Least Informative	Inherited
CTD Chemicals (CC)	Alkaloids	0.3702	Moderately Informative	Inherited
CTD Chemicals (CC)	Hydroxy Acids	0.3909	Moderately Informative	Inherited
CTD Chemicals (CC)	Heterocyclic Compounds, 4 or More Rings	0.6926	Moderately Informative	Inherited
CTD Chemicals (CC)	Phenanthrenes	0.03986	Informative	Inherited
CTD Chemicals (CC)	Morphine Derivatives	0.0001954	Highly Informative	Direct
CTD Chemicals (CC)	Lactates	0.000318	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

Distribution on sTOL

Plot distribution on species Tree Of Life (sTOL) for this domain, i.e., present or absent across genomes/tips

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SNARE fusion complex superfamily