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    > SCOP hierarchy > Inositol polyphosphate 5-phosphatase (IPP5) family

  
  

Inositol polyphosphate 5-phosphatase (IPP5) family

Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   DNase I-like [ 56218]
Superfamily:   DNase I-like [ 56219] (3)
Family:   Inositol polyphosphate 5-phosphatase (IPP5) [ 64422] (2)

HP

Human Phenotype (HP)

HP term FDR (all) SDHP (four levels) Annotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of head or neck0--Direct
Phenotypic Abnormality (PA)Abnormality of the head0--Direct
Phenotypic Abnormality (PA)Abnormality of the skeletal system0--Direct
Phenotypic Abnormality (PA)Abnormal skull morphology0--Direct
Phenotypic Abnormality (PA)Growth abnormality0--Direct
Phenotypic Abnormality (PA)Abnormal muscle tone0--Direct
Phenotypic Abnormality (PA)Abnormal axial skeleton morphology0--Direct
Phenotypic Abnormality (PA)Abnormality of the curvature of the vertebral column0--Direct
Phenotypic Abnormality (PA)Abnormal muscle physiology0--Direct
Phenotypic Abnormality (PA)Abnormal eye morphology0--Direct
Phenotypic Abnormality (PA)Elevated serum creatine kinase0.0005435--Direct
Phenotypic Abnormality (PA)Abnormal circulating creatine kinase concentration0.0005787--Direct
Phenotypic Abnormality (PA)Abnormality of circulating enzyme level0.0006396--Direct
Phenotypic Abnormality (PA)Abnormality of the synovia0.0007849--Direct
Phenotypic Abnormality (PA)Abnormality of the hip bone0.002721--Inherited
Phenotypic Abnormality (PA)Abnormality of pelvic girdle bone morphology0.05076--Inherited
Phenotypic Abnormality (PA)Abnormality of lower limb joint0.112--Inherited
Phenotypic Abnormality (PA)Abnormal appendicular skeleton morphology0.1208--Inherited
Phenotypic Abnormality (PA)Abnormality of the eye0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the musculature0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of limbs0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of metabolism/homeostasis0.08298Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the vertebral column0Moderately InformativeDirect
Phenotypic Abnormality (PA)Muscular hypotonia0Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the lower limb0Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormal circulating metabolite concentration0.005275Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal joint morphology0.1613Moderately InformativeInherited
Phenotypic Abnormality (PA)Scoliosis0InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the hip joint0.0007028InformativeDirect
Phenotypic Abnormality (PA)Abnormality of long bone morphology0.07315InformativeInherited
Phenotypic Abnormality (PA)Abnormal circulating protein level0.09498InformativeInherited
Phenotypic Abnormality (PA)Abnormal vertebral morphology0.1043InformativeInherited
Phenotypic Abnormality (PA)Abnormality of epiphysis morphology0.0003299Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormal form of the vertebral bodies0.0007707Highly InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

MP

Mouse Phenotype (MP)

MP term FDR (all) SDMP (four levels) Annotation (direct or inherited)
Mammalian Phenotype (MP)abnormal postnatal growth/weight/body size0--Direct
Mammalian Phenotype (MP)abnormal body weight0.0001824--Direct
Mammalian Phenotype (MP)abnormal postnatal growth0.07074--Inherited
Mammalian Phenotype (MP)growth/size/body region phenotype0Least InformativeDirect
Mammalian Phenotype (MP)abnormal body size0.5325Moderately InformativeInherited
Mammalian Phenotype (MP)postnatal growth retardation0.0006044InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

WP

Worm Phenotype (WP)

WP term FDR (all) SDWP (four levels) Annotation (direct or inherited)
Worm Phenotype (WP)growth variant0--Direct
Worm Phenotype (WP)developmental timing variant0--Direct
Worm Phenotype (WP)general pace of development variant0--Direct
Worm Phenotype (WP)postembryonic development variant0--Direct
Worm Phenotype (WP)embryonic lethal0--Direct
Worm Phenotype (WP)lethal0--Direct
Worm Phenotype (WP)fertility variant0--Direct
Worm Phenotype (WP)retarded heterochronic variations0--Direct
Worm Phenotype (WP)behavior variant0--Direct
Worm Phenotype (WP)development variant0--Direct
Worm Phenotype (WP)morphology variant0--Direct
Worm Phenotype (WP)organism development variant0--Direct
Worm Phenotype (WP)cell morphology variant0--Direct
Worm Phenotype (WP)organ system morphology variant0--Direct
Worm Phenotype (WP)organism morphology variant0--Direct
Worm Phenotype (WP)organ system physiology variant0--Direct
Worm Phenotype (WP)organism physiology variant0--Direct
Worm Phenotype (WP)organism homeostasis metabolism variant0--Direct
Worm Phenotype (WP)reproductive system physiology variant0--Direct
Worm Phenotype (WP)maternal sterile0--Direct
Worm Phenotype (WP)hermaphrodite sterile0--Direct
Worm Phenotype (WP)gene expression variant0--Direct
Worm Phenotype (WP)embryonic development variant0--Direct
Worm Phenotype (WP)larval development variant0--Direct
Worm Phenotype (WP)hermaphrodite fertility variant0--Direct
Worm Phenotype (WP)developmental growth variant0--Direct
Worm Phenotype (WP)larval growth variant0--Direct
Worm Phenotype (WP)sterile progeny0--Direct
Worm Phenotype (WP)hermaphrodite fertility reduced0--Direct
Worm Phenotype (WP)fertility reduced0--Direct
Worm Phenotype (WP)physiology variant1--Inherited
Worm Phenotype (WP)sterile1--Inherited
Worm Phenotype (WP)organism metabolism processing variant0Least InformativeDirect
Worm Phenotype (WP)slow growth0Least InformativeDirect
Worm Phenotype (WP)larval lethal0Least InformativeDirect
Worm Phenotype (WP)larval arrest0Least InformativeDirect
Worm Phenotype (WP)progeny variant0Least InformativeDirect
Worm Phenotype (WP)organism behavior variant0Least InformativeDirect
Worm Phenotype (WP)cell physiology variant0Least InformativeDirect
Worm Phenotype (WP)organism environmental stimulus response variant0Least InformativeDirect
Worm Phenotype (WP)protein expression variant0Moderately InformativeDirect
Worm Phenotype (WP)cell type morphology variant0Moderately InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

YP

Yeast Phenotype (YP)

YP term FDR (all) SDYP (four levels) Annotation (direct or inherited)
Yeast Phenotype (YP)competitive fitness0--Direct
Yeast Phenotype (YP)fitness0--Direct
Yeast Phenotype (YP)hyperosmotic stress resistance0.00009737--Direct
Yeast Phenotype (YP)stress resistance0.7673--Inherited
Yeast Phenotype (YP)cellular processes0.8217--Inherited
Yeast Phenotype (YP)resistance to chemicals0.5898Least InformativeInherited
Yeast Phenotype (YP)development0.04424Moderately InformativeInherited
Yeast Phenotype (YP)lifespan0.0181InformativeInherited
Yeast Phenotype (YP)osmotic stress resistance0.0001053Highly InformativeDirect
Yeast Phenotype (YP)replicative lifespan0.0001826Highly InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

FP

Fly Phenotype (FP)

FP term FDR (all) SDFP (four levels) Annotation (direct or inherited)
Fly Phenotype (FP)viable0Least InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

FA

Fly Anatomy (FA)

FA term FDR (all) SDFA (four levels) Annotation (direct or inherited)
Fly Anatomy (FA)organism0--Direct
Fly Anatomy (FA)organ system0--Direct
Fly Anatomy (FA)cell0--Direct
Fly Anatomy (FA)non-connected functional system0--Direct
Fly Anatomy (FA)sensory system0--Direct
Fly Anatomy (FA)multicellular structure0--Direct
Fly Anatomy (FA)anatomical structure1--Inherited
Fly Anatomy (FA)material anatomical entity1--Inherited
Fly Anatomy (FA)larva0Least InformativeDirect
Fly Anatomy (FA)anatomical group0Least InformativeDirect
Fly Anatomy (FA)somatic cell0Least InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

XA

Xenopus Anatomy (XA)

XA term FDR (all) SDXA (four levels) Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)trunk region0--Direct
Xenopus ANatomical entity (XAN)anatomical structure0--Direct
Xenopus ANatomical entity (XAN)anatomical group0--Direct
Xenopus ANatomical entity (XAN)organism subdivision0--Direct
Xenopus ANatomical entity (XAN)compound organ0--Direct
Xenopus ANatomical entity (XAN)anatomical region0--Direct
Xenopus ANatomical entity (XAN)multicellular anatomical structure0--Direct
Xenopus ANatomical entity (XAN)anatomical system1--Inherited
Xenopus ANatomical entity (XAN)whole organism1--Inherited
Xenopus ANatomical entity (XAN)urogenital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)trunk0Least InformativeDirect
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

AP

Arabidopsis Plant Ontology (AP)

AP term FDR (all) SDAP (four levels) Annotation (direct or inherited)
Plant ANatomical entity (PAN)plant organ0--Direct
Plant ANatomical entity (PAN)multi-tissue plant structure0--Direct
Plant ANatomical entity (PAN)collective plant structure0--Direct
Plant ANatomical entity (PAN)trichoblast0.00001073--Direct
Plant ANatomical entity (PAN)root hair cell0.00003923--Direct
Plant ANatomical entity (PAN)root epidermis0.0003247--Direct
Plant ANatomical entity (PAN)root system0.02393--Inherited
Plant ANatomical entity (PAN)portion of plant tissue0.6549--Inherited
Plant ANatomical entity (PAN)plant cell0.7709--Inherited
Plant ANatomical entity (PAN)epidermal cell0.7881--Inherited
Plant ANatomical entity (PAN)epidermis0.8374--Inherited
Plant ANatomical entity (PAN)plant structure1--Inherited
Plant ANatomical entity (PAN)collective plant organ structure1--Inherited
Plant ANatomical entity (PAN)root epidermal cell0.000129Highly InformativeDirect
 
AP term FDR (all) SDAP (four levels) Annotation (direct or inherited)
Plant structure DEvelopment stage (PDE)sporophyte vegetative stage0.9332--Inherited
Plant structure DEvelopment stage (PDE)whole plant development stage0.9364--Inherited
Plant structure DEvelopment stage (PDE)life of whole plant stage1--Inherited
Plant structure DEvelopment stage (PDE)sporophyte development stage1--Inherited
Plant structure DEvelopment stage (PDE)seedling development stage0.000352InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

EC

Enzyme Commission (EC)

EC term FDR (all) SDEC (four levels) Annotation (direct or inherited)
Enzyme Commission (EC)Phosphoinositide 5-phosphatase0--Direct
Enzyme Commission (EC)Inositol-polyphosphate 5-phosphatase0--Direct
Enzyme Commission (EC)Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase0--Direct
Enzyme Commission (EC)Hydrolases0Least InformativeDirect
Enzyme Commission (EC)Acting on ester bonds0Moderately InformativeDirect
Enzyme Commission (EC)Phosphoric monoester hydrolases0InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

CC

CTD Chemicals (CC)

CC term FDR (all) SDCC (four levels) Annotation (direct or inherited)
CTD Chemicals (CC)Heterocyclic Compounds0--Direct
CTD Chemicals (CC)Heterocyclic Compounds, 1-Ring0--Direct
CTD Chemicals (CC)Hydrocarbons0--Direct
CTD Chemicals (CC)Inorganic Chemicals0--Direct
CTD Chemicals (CC)Organic Chemicals0--Direct
CTD Chemicals (CC)Pyrimidines0Least InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

Distribution on sTOL

Plot distribution on species Tree Of Life (sTOL) for this domain, i.e., present or absent across genomes/tips
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Locations of visitors to this page Using dcGO in your work, please cite Nucleic Acids Research 2013, 41(Database issue):D536-44.
On questions and detailed information, please contact Dr. Hai Fang or Prof. Julian Gough