Pyridoxal-dependent decarboxylase family

DO

Disease Ontology (DO)

	DO term	FDR (all)	SDDO (four levels)	Annotation (direct or inherited)
Disease Ontology (DO)	substance-related disorder	0.01321	--	Inherited
Disease Ontology (DO)	disease of mental health	0.001232	Moderately Informative	Inherited
Disease Ontology (DO)	substance dependence	0.0001293	Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

HP

Human Phenotype (HP)

	HP term	FDR (all)	SDHP (four levels)	Annotation (direct or inherited)
Phenotypic Abnormality (PA)	Abnormality of the nervous system	0	--	Direct
Phenotypic Abnormality (PA)	Abnormality of nervous system physiology	0	Least Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

MP

Mouse Phenotype (MP)

	MP term	FDR (all)	SDMP (four levels)	Annotation (direct or inherited)
Mammalian Phenotype (MP)	abnormal neurotransmitter level	0.00001749	--	Direct
Mammalian Phenotype (MP)	increased anxiety-related response	0.00008264	--	Direct
Mammalian Phenotype (MP)	abnormal palate morphology	0.0003136	--	Direct
Mammalian Phenotype (MP)	abnormal fear/anxiety-related behavior	0.0006052	--	Direct
Mammalian Phenotype (MP)	abnormal facial morphology	0.004389	--	Inherited
Mammalian Phenotype (MP)	abnormal nervous system physiology	0.01376	--	Inherited
Mammalian Phenotype (MP)	craniofacial phenotype	0.01529	--	Inherited
Mammalian Phenotype (MP)	digestive/alimentary phenotype	0.02913	--	Inherited
Mammalian Phenotype (MP)	behavior/neurological phenotype	0.07306	--	Inherited
Mammalian Phenotype (MP)	growth/size/body region phenotype	0.03021	Least Informative	Inherited
Mammalian Phenotype (MP)	nervous system phenotype	0.08333	Least Informative	Inherited
Mammalian Phenotype (MP)	abnormal synaptic transmission	0.0003908	Moderately Informative	Direct
Mammalian Phenotype (MP)	abnormal craniofacial morphology	0.01514	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal digestive system morphology	0.01529	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal head morphology	0.04068	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal behavior	1	Moderately Informative	Inherited
Mammalian Phenotype (MP)	abnormal mouth morphology	0.001654	Informative	Inherited
Mammalian Phenotype (MP)	abnormal emotion/affect behavior	0.009812	Informative	Inherited
Mammalian Phenotype (MP)	abnormal CNS synaptic transmission	0.7117	Informative	Inherited
Mammalian Phenotype (MP)	abnormal inhibitory postsynaptic currents	0.00000579	Highly Informative	Direct
Mammalian Phenotype (MP)	cleft palate	0.0002107	Highly Informative	Direct
Mammalian Phenotype (MP)	abnormal anxiety-related response	0.0004156	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

WP

Worm Phenotype (WP)

	WP term	FDR (all)	SDWP (four levels)	Annotation (direct or inherited)
Worm Phenotype (WP)	postembryonic development variant	0	--	Direct
Worm Phenotype (WP)	embryonic lethal	0	--	Direct
Worm Phenotype (WP)	lethal	0	--	Direct
Worm Phenotype (WP)	fertility variant	0	--	Direct
Worm Phenotype (WP)	development variant	0	--	Direct
Worm Phenotype (WP)	morphology variant	0	--	Direct
Worm Phenotype (WP)	organism development variant	0	--	Direct
Worm Phenotype (WP)	organism morphology variant	0	--	Direct
Worm Phenotype (WP)	organ system physiology variant	0	--	Direct
Worm Phenotype (WP)	reproductive system physiology variant	0	--	Direct
Worm Phenotype (WP)	maternal sterile	0	--	Direct
Worm Phenotype (WP)	hermaphrodite sterile	0	--	Direct
Worm Phenotype (WP)	embryonic development variant	0	--	Direct
Worm Phenotype (WP)	hermaphrodite fertility variant	0	--	Direct
Worm Phenotype (WP)	hermaphrodite fertility reduced	0	--	Direct
Worm Phenotype (WP)	fertility reduced	0	--	Direct
Worm Phenotype (WP)	body posture amplitude increased	0.0000009565	--	Direct
Worm Phenotype (WP)	path curvature decreased	0.000002321	--	Direct
Worm Phenotype (WP)	forward locomotion increased	0.000002935	--	Direct
Worm Phenotype (WP)	backward locomotion variant	0.000003303	--	Direct
Worm Phenotype (WP)	reversal variant	0.00000378	--	Direct
Worm Phenotype (WP)	forward point velocity increased	0.00000408	--	Direct
Worm Phenotype (WP)	localized movement variant	0.000004199	--	Direct
Worm Phenotype (WP)	roaming increased	0.000004525	--	Direct
Worm Phenotype (WP)	backward point velocity increased	0.000004525	--	Direct
Worm Phenotype (WP)	carbon dioxide response variant	0.000006075	--	Direct
Worm Phenotype (WP)	directionality variant	0.000006549	--	Direct
Worm Phenotype (WP)	body bend variant	0.00001163	--	Direct
Worm Phenotype (WP)	sinusoidal movement variant	0.00001237	--	Direct
Worm Phenotype (WP)	turning frequency variant	0.00007207	--	Direct
Worm Phenotype (WP)	activity level variant	0.0002607	--	Direct
Worm Phenotype (WP)	anesthetic response variant	0.001476	--	Inherited
Worm Phenotype (WP)	locomotion variant	0.02942	--	Inherited
Worm Phenotype (WP)	behavior variant	0.05552	--	Inherited
Worm Phenotype (WP)	drug response variant	0.1223	--	Inherited
Worm Phenotype (WP)	organism homeostasis metabolism variant	0.4714	--	Inherited
Worm Phenotype (WP)	organism physiology variant	0.4902	--	Inherited
Worm Phenotype (WP)	turning variant	0.4955	--	Inherited
Worm Phenotype (WP)	tail movement variant	0.7141	--	Inherited
Worm Phenotype (WP)	physiology variant	1	--	Inherited
Worm Phenotype (WP)	sterile	1	--	Inherited
Worm Phenotype (WP)	organism environmental stimulus response variant	0.006395	Least Informative	Inherited
Worm Phenotype (WP)	organism behavior variant	0.05447	Least Informative	Inherited
Worm Phenotype (WP)	chemical response variant	0.05706	Moderately Informative	Inherited
Worm Phenotype (WP)	movement variant	0.1482	Moderately Informative	Inherited
Worm Phenotype (WP)	foraging behavior variant	0.000001355	Informative	Direct
Worm Phenotype (WP)	head movement variant	0.00000378	Informative	Direct
Worm Phenotype (WP)	locomotor coordination variant	0.00008192	Informative	Direct
Worm Phenotype (WP)	tail bend angle variant	0.0000832	Informative	Direct
Worm Phenotype (WP)	egg laying variant	0.0001434	Informative	Direct
Worm Phenotype (WP)	forward locomotion variant	0.0003209	Informative	Direct
Worm Phenotype (WP)	body posture variant	0.0008003	Informative	Direct
Worm Phenotype (WP)	velocity of movement variant	0.04276	Informative	Inherited
Worm Phenotype (WP)	amplitude of sinusoidal movement variant	0.000003985	Highly Informative	Direct
Worm Phenotype (WP)	carbon dioxide avoidance variant	0.000005522	Highly Informative	Direct
Worm Phenotype (WP)	body posture wavelength variant	0.00005455	Highly Informative	Direct
Worm Phenotype (WP)	forward point velocity variant	0.00006052	Highly Informative	Direct
Worm Phenotype (WP)	body posture amplitude variant	0.00006694	Highly Informative	Direct
Worm Phenotype (WP)	backward point velocity variant	0.00006861	Highly Informative	Direct
Worm Phenotype (WP)	egg laying response to drug variant	0.0001727	Highly Informative	Direct
Worm Phenotype (WP)	roaming variant	0.02057	Highly Informative	Inherited
Worm Phenotype (WP)	foraging hyperactive	0.03485	Highly Informative	Inherited
Worm Phenotype (WP)	path curvature variant	0.05511	Highly Informative	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

FA

Fly Anatomy (FA)

	FA term	FDR (all)	SDFA (four levels)	Annotation (direct or inherited)
Fly Anatomy (FA)	organism	0	--	Direct
Fly Anatomy (FA)	organ system	0	--	Direct
Fly Anatomy (FA)	multicellular structure	0	--	Direct
Fly Anatomy (FA)	anatomical structure	1	--	Inherited
Fly Anatomy (FA)	material anatomical entity	1	--	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

ZA

Zebrafish Anatomy (ZA)

	ZA term	FDR (all)	SDZA (four levels)	Annotation (direct or inherited)
Zebrafish Anatomy (ZA)	compound organ	0	--	Direct
Zebrafish Anatomy (ZA)	whole organism	0	--	Direct
Zebrafish Anatomy (ZA)	anatomical system	0	--	Direct
Zebrafish Anatomy (ZA)	anatomical group	0	--	Direct
Zebrafish Anatomy (ZA)	anatomical structure	1	--	Inherited
Zebrafish Anatomy (ZA)	multi-tissue structure	0	Least Informative	Direct
Zebrafish Anatomy (ZA)	cavitated compound organ	0	Least Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

XA

Xenopus Anatomy (XA)

	XA term	FDR (all)	SDXA (four levels)	Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)	anatomical structure	0	--	Direct
Xenopus ANatomical entity (XAN)	organism subdivision	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical region	0	--	Direct
Xenopus ANatomical entity (XAN)	multicellular anatomical structure	0	--	Direct
Xenopus ANatomical entity (XAN)	whole organism	1	--	Inherited

	XA term	FDR (all)	SDXA (four levels)	Annotation (direct or inherited)
Xenopus DEvelopment stage (XDE)	NF stage	0	--	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

AP

Arabidopsis Plant Ontology (AP)

	AP term	FDR (all)	SDAP (four levels)	Annotation (direct or inherited)
Plant ANatomical entity (PAN)	shoot system	0	--	Direct
Plant ANatomical entity (PAN)	collective plant structure	0	--	Direct
Plant ANatomical entity (PAN)	plant structure	1	--	Inherited
Plant ANatomical entity (PAN)	collective plant organ structure	1	--	Inherited

	AP term	FDR (all)	SDAP (four levels)	Annotation (direct or inherited)
Plant structure DEvelopment stage (PDE)	whole plant development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	sporophyte vegetative stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	floral organ differentiation stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	corolla development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	flowering stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	plant embryo stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	collective plant organ structure development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	plant organ development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	reproductive shoot system development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	collective phyllome structure development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	phyllome development stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	floral organ formation stage	0	--	Direct
Plant structure DEvelopment stage (PDE)	leaf development stage	1	--	Inherited
Plant structure DEvelopment stage (PDE)	flower development stage	1	--	Inherited
Plant structure DEvelopment stage (PDE)	life of whole plant stage	1	--	Inherited
Plant structure DEvelopment stage (PDE)	shoot system development stage	1	--	Inherited
Plant structure DEvelopment stage (PDE)	sporophyte development stage	1	--	Inherited
Plant structure DEvelopment stage (PDE)	4 leaf senescence stage	0	Least Informative	Direct
Plant structure DEvelopment stage (PDE)	E expanded cotyledon stage	0	Least Informative	Direct
Plant structure DEvelopment stage (PDE)	F mature embryo stage	0	Least Informative	Direct
Plant structure DEvelopment stage (PDE)	C globular stage	0	Least Informative	Direct
Plant structure DEvelopment stage (PDE)	D bilateral stage	0	Least Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

EC

Enzyme Commission (EC)

	EC term	FDR (all)	SDEC (four levels)	Annotation (direct or inherited)
Enzyme Commission (EC)	Carbon-carbon lyases	0	--	Direct
Enzyme Commission (EC)	Glutamate decarboxylase	0	--	Direct
Enzyme Commission (EC)	Tyrosine decarboxylase	0	--	Direct
Enzyme Commission (EC)	Aromatic-L-amino-acid decarboxylase	0	--	Direct
Enzyme Commission (EC)	Sphinganine-1-phosphate aldolase	0	--	Direct
Enzyme Commission (EC)	Aspartate 1-decarboxylase	0.00000000000001351	--	Direct
Enzyme Commission (EC)	Sulfinoalanine decarboxylase	0.0000000002451	--	Direct
Enzyme Commission (EC)	Histidine decarboxylase	0.00000007136	--	Direct
Enzyme Commission (EC)	3,4-dihydroxyphenylacetaldehyde synthase	0.0000002296	--	Direct
Enzyme Commission (EC)	L-tryptophan decarboxylase	0.000003137	--	Direct
Enzyme Commission (EC)	Diaminobutyrate decarboxylase	0.000003137	--	Direct
Enzyme Commission (EC)	Lyases	0	Moderately Informative	Direct
Enzyme Commission (EC)	Carboxy-lyases	0.00000000502	Informative	Direct
Enzyme Commission (EC)	Aldehyde-lyases	0.8812	Highly Informative	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

CC

CTD Chemicals (CC)

	CC term	FDR (all)	SDCC (four levels)	Annotation (direct or inherited)
CTD Chemicals (CC)	Heterocyclic Compounds, Fused-Ring	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds, 1-Ring	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds, 2-Ring	0	--	Direct
CTD Chemicals (CC)	Inorganic Chemicals	0	--	Direct
CTD Chemicals (CC)	Elements	0	Least Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

Distribution on sTOL

Plot distribution on species Tree Of Life (sTOL) for this domain, i.e., present or absent across genomes/tips

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Pyridoxal-dependent decarboxylase family