Proprotein convertase P-domain family

DO

Disease Ontology (DO)

	DO term	FDR (all)	SDDO (four levels)	Annotation (direct or inherited)
Disease Ontology (DO)	disease of cellular proliferation	0	--	Direct
Disease Ontology (DO)	cancer	0	--	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

MP

Mouse Phenotype (MP)

	MP term	FDR (all)	SDMP (four levels)	Annotation (direct or inherited)
Mammalian Phenotype (MP)	abnormal digit morphology	0.0002682	--	Direct
Mammalian Phenotype (MP)	embryonic lethality prior to tooth bud stage	0.0003109	--	Direct
Mammalian Phenotype (MP)	abnormal limb morphology	0.005347	--	Inherited
Mammalian Phenotype (MP)	embryonic lethality	0.008236	--	Inherited
Mammalian Phenotype (MP)	preweaning lethality	0.1416	--	Inherited
Mammalian Phenotype (MP)	abnormal survival	0.2119	--	Inherited
Mammalian Phenotype (MP)	mortality/aging	0.2574	Least Informative	Inherited
Mammalian Phenotype (MP)	limbs/digits/tail phenotype	0.01071	Moderately Informative	Inherited
Mammalian Phenotype (MP)	prenatal lethality	0.02397	Moderately Informative	Inherited
Mammalian Phenotype (MP)	embryonic lethality prior to organogenesis	0.0002074	Informative	Direct
Mammalian Phenotype (MP)	abnormal autopod morphology	0.0005174	Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

WP

Worm Phenotype (WP)

	WP term	FDR (all)	SDWP (four levels)	Annotation (direct or inherited)
Worm Phenotype (WP)	growth variant	0	--	Direct
Worm Phenotype (WP)	postembryonic development variant	0	--	Direct
Worm Phenotype (WP)	embryonic lethal	0	--	Direct
Worm Phenotype (WP)	lethal	0	--	Direct
Worm Phenotype (WP)	fertility variant	0	--	Direct
Worm Phenotype (WP)	development variant	0	--	Direct
Worm Phenotype (WP)	morphology variant	0	--	Direct
Worm Phenotype (WP)	organism development variant	0	--	Direct
Worm Phenotype (WP)	organ system morphology variant	0	--	Direct
Worm Phenotype (WP)	organism morphology variant	0	--	Direct
Worm Phenotype (WP)	organ system physiology variant	0	--	Direct
Worm Phenotype (WP)	organism physiology variant	0	--	Direct
Worm Phenotype (WP)	organism homeostasis metabolism variant	0	--	Direct
Worm Phenotype (WP)	reproductive system physiology variant	0	--	Direct
Worm Phenotype (WP)	maternal sterile	0	--	Direct
Worm Phenotype (WP)	hermaphrodite sterile	0	--	Direct
Worm Phenotype (WP)	embryonic development variant	0	--	Direct
Worm Phenotype (WP)	larval development variant	0	--	Direct
Worm Phenotype (WP)	hermaphrodite fertility variant	0	--	Direct
Worm Phenotype (WP)	developmental growth variant	0	--	Direct
Worm Phenotype (WP)	larval growth variant	0	--	Direct
Worm Phenotype (WP)	hermaphrodite fertility reduced	0	--	Direct
Worm Phenotype (WP)	fertility reduced	0	--	Direct
Worm Phenotype (WP)	basement membrane remodeling variant	0	--	Direct
Worm Phenotype (WP)	body length variant	0.000151	--	Direct
Worm Phenotype (WP)	hermaphrodite reproductive system morphology variant	0.0001548	--	Direct
Worm Phenotype (WP)	body width variant	0.0002175	--	Direct
Worm Phenotype (WP)	body size variant	0.0003429	--	Direct
Worm Phenotype (WP)	body morphology variant	0.0004572	--	Direct
Worm Phenotype (WP)	physiology variant	1	--	Inherited
Worm Phenotype (WP)	sterile	1	--	Inherited
Worm Phenotype (WP)	larval arrest	0	Least Informative	Direct
Worm Phenotype (WP)	pericellular component development variant	0	Moderately Informative	Direct
Worm Phenotype (WP)	organism segment morphology variant	0.0008675	Moderately Informative	Direct
Worm Phenotype (WP)	body region morphology variant	0.0008786	Moderately Informative	Direct
Worm Phenotype (WP)	reproductive system morphology variant	0.2106	Moderately Informative	Inherited
Worm Phenotype (WP)	vulva morphology variant	0.0001529	Informative	Direct
Worm Phenotype (WP)	dumpy	0.000005692	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

ZA

Zebrafish Anatomy (ZA)

	ZA term	FDR (all)	SDZA (four levels)	Annotation (direct or inherited)
Zebrafish Anatomy (ZA)	whole organism	0	--	Direct
Zebrafish Anatomy (ZA)	anatomical system	0	--	Direct
Zebrafish Anatomy (ZA)	anatomical group	0	--	Direct
Zebrafish Anatomy (ZA)	anatomical structure	1	--	Inherited
Zebrafish Anatomy (ZA)	organism subdivision	0	Least Informative	Direct
Zebrafish Anatomy (ZA)	anatomical cluster	0	Least Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

XA

Xenopus Anatomy (XA)

	XA term	FDR (all)	SDXA (four levels)	Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)	anatomical structure	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical group	0	--	Direct
Xenopus ANatomical entity (XAN)	organism subdivision	0	--	Direct
Xenopus ANatomical entity (XAN)	compound organ	0	--	Direct
Xenopus ANatomical entity (XAN)	anatomical region	0	--	Direct
Xenopus ANatomical entity (XAN)	multicellular anatomical structure	0	--	Direct
Xenopus ANatomical entity (XAN)	whole organism	1	--	Inherited
Xenopus ANatomical entity (XAN)	cavitated compound organ	0	Least Informative	Direct
Xenopus ANatomical entity (XAN)	embryo	0.6292	Least Informative	Inherited
Xenopus ANatomical entity (XAN)	tissue	0.9202	Least Informative	Inherited
Xenopus ANatomical entity (XAN)	animal hemisphere	0.0004608	Informative	Direct
Xenopus ANatomical entity (XAN)	notochord	0.0007199	Informative	Direct
Xenopus ANatomical entity (XAN)	vegetal hemisphere	0.000002144	Highly Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

EC

Enzyme Commission (EC)

	EC term	FDR (all)	SDEC (four levels)	Annotation (direct or inherited)
Enzyme Commission (EC)	Furin	0	--	Direct
Enzyme Commission (EC)	Proprotein convertase 2	0.00000000000004039	--	Direct
Enzyme Commission (EC)	Proprotein convertase 1	0.00000000006756	--	Direct
Enzyme Commission (EC)	Hydrolases	0	Least Informative	Direct
Enzyme Commission (EC)	Acting on peptide bonds (peptidases)	0	Moderately Informative	Direct
Enzyme Commission (EC)	Serine endopeptidases	0.0000000000006736	Informative	Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

CC

CTD Chemicals (CC)

	CC term	FDR (all)	SDCC (four levels)	Annotation (direct or inherited)
CTD Chemicals (CC)	Heterocyclic Compounds, Fused-Ring	0	--	Direct
CTD Chemicals (CC)	Carboxylic Acids	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds, 1-Ring	0	--	Direct
CTD Chemicals (CC)	Heterocyclic Compounds, 2-Ring	0	--	Direct
CTD Chemicals (CC)	Inorganic Chemicals	0	--	Direct
CTD Chemicals (CC)	Mycotoxins	0	--	Direct
CTD Chemicals (CC)	Organic Chemicals	0	--	Direct
CTD Chemicals (CC)	Polycyclic Compounds	0	--	Direct
CTD Chemicals (CC)	Pyrans	0	--	Direct
CTD Chemicals (CC)	Toxins, Biological	0	--	Direct
CTD Chemicals (CC)	Aflatoxin B1	0	--	Direct
CTD Chemicals (CC)	Amino Acids, Aromatic	0.0002397	--	Direct
CTD Chemicals (CC)	Aspirin	0.0005738	--	Direct
CTD Chemicals (CC)	Hydroxybenzoates	0.003101	--	Inherited
CTD Chemicals (CC)	Benzene Derivatives	0.261	--	Inherited
CTD Chemicals (CC)	Hydrocarbons, Aromatic	0.5397	--	Inherited
CTD Chemicals (CC)	Hydrocarbons, Cyclic	0.5731	--	Inherited
CTD Chemicals (CC)	Hydrocarbons	0.6966	--	Inherited
CTD Chemicals (CC)	Benzopyrans	0	Least Informative	Direct
CTD Chemicals (CC)	Biological Factors	0	Least Informative	Direct
CTD Chemicals (CC)	Electrolytes	0	Least Informative	Direct
CTD Chemicals (CC)	Indoles	0	Least Informative	Direct
CTD Chemicals (CC)	Amino Acids, Peptides, and Proteins	0.03164	Least Informative	Inherited
CTD Chemicals (CC)	Phenols	0.081	Least Informative	Inherited
CTD Chemicals (CC)	Acids, Carbocyclic	0.0822	Least Informative	Inherited
CTD Chemicals (CC)	Aflatoxins	0	Moderately Informative	Direct
CTD Chemicals (CC)	Benzoates	0.02009	Moderately Informative	Inherited
CTD Chemicals (CC)	Amino Acids	0.05662	Moderately Informative	Inherited
CTD Chemicals (CC)	Hydroxy Acids	0.2148	Moderately Informative	Inherited
CTD Chemicals (CC)	Amino Acids, Cyclic	0.00038	Informative	Direct
CTD Chemicals (CC)	Salicylates	0.001278	Informative	Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

Distribution on sTOL

Plot distribution on species Tree Of Life (sTOL) for this domain, i.e., present or absent across genomes/tips

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Proprotein convertase P-domain family