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DnaQ-like 3'-5' exonuclease family

Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Ribonuclease H-like motif [ 53066] (7)
Superfamily:   Ribonuclease H-like [ 53098] (14)
Family:   DnaQ-like 3'-5' exonuclease [ 53118] (15)

HP

Human Phenotype (HP)

HP term FDR (all) SDHP (four levels) Annotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormal large intestine morphology0.0008866--Direct
Phenotypic Abnormality (PA)Abnormality of skin morphology0.01837--Inherited
Phenotypic Abnormality (PA)Abnormality of the skin0.02579--Inherited
Phenotypic Abnormality (PA)Abnormality of the vasculature0.06858--Inherited
Phenotypic Abnormality (PA)Generalized abnormality of skin0.3189--Inherited
Phenotypic Abnormality (PA)Morphological abnormality of the gastrointestinal tract0.3593--Inherited
Phenotypic Abnormality (PA)Abnormality of the integument0.05646Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the digestive system0.07845Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cardiovascular system0.225Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the gastrointestinal tract0.006528Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of digestive system morphology0.05201Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the voice0.0004185InformativeDirect
Phenotypic Abnormality (PA)Vascular skin abnormality0.02776InformativeInherited
Phenotypic Abnormality (PA)Abnormal intestine morphology0.2829InformativeInherited
Phenotypic Abnormality (PA)Telangiectasia0.0001032Highly InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

MP

Mouse Phenotype (MP)

MP term FDR (all) SDMP (four levels) Annotation (direct or inherited)
Mammalian Phenotype (MP)increased thymus tumor incidence0.0001584--Direct
Mammalian Phenotype (MP)increased lymphoma incidence0.002408--Inherited
Mammalian Phenotype (MP)increased tumor incidence0.01313--Inherited
Mammalian Phenotype (MP)abnormal tumor incidence0.02018--Inherited
Mammalian Phenotype (MP)altered tumor susceptibility0.02129--Inherited
Mammalian Phenotype (MP)abnormal gland morphology0.1061--Inherited
Mammalian Phenotype (MP)abnormal classified tumor incidence0.3914--Inherited
Mammalian Phenotype (MP)abnormal organ/body region tumor incidence0.4873--Inherited
Mammalian Phenotype (MP)increased classified tumor incidence0.5306--Inherited
Mammalian Phenotype (MP)increased organ/body region tumor incidence0.6249--Inherited
Mammalian Phenotype (MP)endocrine/exocrine gland phenotype0.1351Least InformativeInherited
Mammalian Phenotype (MP)neoplasm0.02915Moderately InformativeInherited
Mammalian Phenotype (MP)increased hemolymphoid system tumor incidence0.004436InformativeInherited
Mammalian Phenotype (MP)increased gland tumor incidence0.009792InformativeInherited
Mammalian Phenotype (MP)increased malignant tumor incidence0.01005InformativeInherited
Mammalian Phenotype (MP)increased T cell derived lymphoma incidence0.0001522Highly InformativeDirect
Mammalian Phenotype (MP)increased sarcoma incidence0.0004595Highly InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

WP

Worm Phenotype (WP)

WP term FDR (all) SDWP (four levels) Annotation (direct or inherited)
Worm Phenotype (WP)embryonic lethal0--Direct
Worm Phenotype (WP)lethal0--Direct
Worm Phenotype (WP)development variant0--Direct
Worm Phenotype (WP)morphology variant0--Direct
Worm Phenotype (WP)organism development variant0--Direct
Worm Phenotype (WP)embryonic development variant0--Direct
Worm Phenotype (WP)RNAi response variant0.0006954--Direct
Worm Phenotype (WP)embryonic cell physiology variant0.002672--Inherited
Worm Phenotype (WP)cell component morphology variant0.1077--Inherited
Worm Phenotype (WP)cell morphology variant0.2284--Inherited
Worm Phenotype (WP)organism physiology variant0.2539--Inherited
Worm Phenotype (WP)physiology variant1--Inherited
Worm Phenotype (WP)organism homeostasis metabolism variant1--Inherited
Worm Phenotype (WP)cell physiology variant0.04312Least InformativeInherited
Worm Phenotype (WP)cell organization biogenesis variant0.04096Moderately InformativeInherited
Worm Phenotype (WP)embryonic cell organization biogenesis variant0.0005568InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

YP

Yeast Phenotype (YP)

YP term FDR (all) SDYP (four levels) Annotation (direct or inherited)
Yeast Phenotype (YP)cellular processes0--Direct
Yeast Phenotype (YP)stress resistance0--Direct
Yeast Phenotype (YP)competitive fitness0--Direct
Yeast Phenotype (YP)fitness0--Direct
Yeast Phenotype (YP)resistance to chemicals0Least InformativeDirect
Yeast Phenotype (YP)chromosome/plasmid maintenance0.06273InformativeInherited
Yeast Phenotype (YP)mutation frequency0.00003403Highly InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

FA

Fly Anatomy (FA)

FA term FDR (all) SDFA (four levels) Annotation (direct or inherited)
Fly Anatomy (FA)organism0--Direct
Fly Anatomy (FA)multicellular structure0--Direct
Fly Anatomy (FA)anatomical structure1--Inherited
Fly Anatomy (FA)material anatomical entity1--Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

ZA

Zebrafish Anatomy (ZA)

ZA term FDR (all) SDZA (four levels) Annotation (direct or inherited)
Zebrafish Anatomy (ZA)whole organism0--Direct
Zebrafish Anatomy (ZA)anatomical structure1--Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

XA

Xenopus Anatomy (XA)

XA term FDR (all) SDXA (four levels) Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)anatomical structure0--Direct
 
XA term FDR (all) SDXA (four levels) Annotation (direct or inherited)
Xenopus DEvelopment stage (XDE)NF stage0--Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

AP

Arabidopsis Plant Ontology (AP)

AP term FDR (all) SDAP (four levels) Annotation (direct or inherited)
Plant ANatomical entity (PAN)plant cell0--Direct
Plant ANatomical entity (PAN)shoot system0--Direct
Plant ANatomical entity (PAN)collective plant structure0--Direct
Plant ANatomical entity (PAN)plant structure1--Inherited
Plant ANatomical entity (PAN)collective plant organ structure1--Inherited
 
AP term FDR (all) SDAP (four levels) Annotation (direct or inherited)
Plant structure DEvelopment stage (PDE)floral organ differentiation stage0--Direct
Plant structure DEvelopment stage (PDE)collective plant organ structure development stage0--Direct
Plant structure DEvelopment stage (PDE)plant organ development stage0--Direct
Plant structure DEvelopment stage (PDE)reproductive shoot system development stage0--Direct
Plant structure DEvelopment stage (PDE)collective phyllome structure development stage0--Direct
Plant structure DEvelopment stage (PDE)floral organ formation stage0--Direct
Plant structure DEvelopment stage (PDE)flower development stage1--Inherited
Plant structure DEvelopment stage (PDE)shoot system development stage1--Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

EC

Enzyme Commission (EC)

EC term FDR (all) SDEC (four levels) Annotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorus-containing groups0--Direct
Enzyme Commission (EC)Exodeoxyribonuclease I0.0000000003603--Direct
Enzyme Commission (EC)Ribonuclease D0.0000000006231--Direct
Enzyme Commission (EC)Ribonuclease H0.000000003143--Direct
Enzyme Commission (EC)Poly(A)-specific ribonuclease0.0000001901--Direct
Enzyme Commission (EC)Exodeoxyribonuclease III0.0000006872--Direct
Enzyme Commission (EC)Exodeoxyribonucleases producing 5'-phosphomonoesters0.000006089--Direct
Enzyme Commission (EC)Endoribonucleases producing 5'-phosphomonoesters0.9516--Inherited
Enzyme Commission (EC)Transferases0Least InformativeDirect
Enzyme Commission (EC)Hydrolases0.004738Least InformativeInherited
Enzyme Commission (EC)Nucleotidyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Acting on ester bonds0Moderately InformativeDirect
Enzyme Commission (EC)DNA-directed DNA polymerase0InformativeDirect
Enzyme Commission (EC)Exoribonucleases producing 5'-phosphomonoesters0Highly InformativeDirect

LINKTO: Domain2BO Download and Domain2BO Algorithm

CC

CTD Chemicals (CC)

CC term FDR (all) SDCC (four levels) Annotation (direct or inherited)
CTD Chemicals (CC)Heterocyclic Compounds, Fused-Ring0--Direct
CTD Chemicals (CC)Heterocyclic Compounds0--Direct
CTD Chemicals (CC)Heterocyclic Compounds, 1-Ring0--Direct
CTD Chemicals (CC)Organic Chemicals0--Direct

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Distribution on sTOL

Plot distribution on species Tree Of Life (sTOL) for this domain, i.e., present or absent across genomes/tips
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