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CTD Chemicals (CC): Eicosanoids  
(show info)
Biomedical Ontology
Like Gene Ontology (GO), biomedical ontology such as phenotype ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Biomedical ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI’s thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology Based on YP which is the major contributor to the ‘Ascomycete phenotype ontology’, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- UniProtKB KeyWords (KW) Ontology Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- CTD Diseases (CD) Ontology CD is MEDIC disease vocabulary that is modified by CTD from the "Diseases" [C] branch of Medical Subject Headings (MeSH), combined with genetic disorders from the Online Mendelian Inheritance in OMIM database.
- CTD Chemicals (CC) Ontology CC is chemical vocabulary that is adapted by CTD from the "Chemicals and Drugs" category and Supplementary Concept Records of Medical Subject Headings (MeSH, a hierarchical vocabulary used to index articles for MEDLINE/PubMed).
Jump to [ Top · Hierarchy · Annotations ]
Root: CC Hierarchy (CTD chemicals from Comparative Toxicogenomics Database)
| Shortest distance to current term (+ for parents, - for children) |
CC term [CC ID] <#Children> |
#Domains (Superfamily|Family) |
#Supra-domain (Single|Duplex|Triple) |
| + + + + 4: | Chemicals [MESH:D] <13> |
| + + + 3: | Biological Factors [MESH:D001685] <39> | (253|342) |
(261|248|150) |
| + + + 3: | Lipids [MESH:D008055] <125> | (304|430) |
(309|270|137) |
| + + 2: | Inflammation Mediators [MESH:D018836] <3> | (39|39) |
(41|20|10) |
| + + 2: | Fatty Acids [MESH:D005227] <230> | (246|355) |
(248|222|117) |
| + 1: | Fatty Acids, Unsaturated [MESH:D005231] <444> | (60|64) |
(61|33|11) |
| + 1: | Autacoids [MESH:D012898] <6> | (37|37) |
(38|17|7) |
| 0: | Eicosanoids [MESH:D015777] <14> | (30|33) |
(31|16|7) |
| - 1: | Arachidonic Acids [MESH:D001095] <94> | (16|18) |
(16|8|3) |
| - 1: | 8,11,14-Eicosatrienoic Acid [MESH:D015126] <50> | (1|1) |
(1|0|0) |
| - 1: | Eicosapentaenoic Acid [MESH:D015118] <37> | (1|0) |
(1|0|0) |
| - 1: | Prostaglandins [MESH:D011453] <31> | (18|20) |
(20|5|2) |
| - 1: | Leukotrienes [MESH:D015289] <15> | (2|2) |
(2|1|0) |
| - 1: | Lipoxins [MESH:D044045] <14> | (0|0) |
(0|1|1) |
| - 1: | 5,8,11,14-Eicosatetraynoic Acid [MESH:D015117] <3> | (0|0) |
(0|0|0) |
| - 1: | (8-hydroxymethylen)trieicosanyl acetate [MESH:C534089] | (0|0) |
(0|0|0) |
| - 1: | 14-ethyl-2,5,11-trimethyl-4,13,19,20-tetraoxa-tricyclo(14.2.1.1(7,10))eicosane-3,12-dione [MESH:C526293] | (0|0) |
(0|0|0) |
| - 1: | N1-(4-isothiocyanatobenzyl)-3,6,10,13,16,19-hexaaza bicyclo(6.6.6)icosane-1,8-diamine [MESH:C584874] | (0|0) |
(0|0|0) |
| - 1: | U 49619 [MESH:C062714] | (0|0) |
(0|0|0) |
| - 1: | lipoxin C4 [MESH:C073550] | (0|0) |
(0|0|0) |
| - 1: | methyl 6-eicosanyl-2-hydroxy-4-methoxybenzoate [MESH:C503470] | (0|0) |
(0|0|0) |
| - 1: | solandelactone F [MESH:C523382] | (0|0) |
(0|0|0) |
Jump to [ Top · Hierarchy ]
Superfamily( show details)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| Lipoxigenase | 0.000001846 | DIRECT |
| GST C-terminal domain-like | 0.000002268 | DIRECT |
| Cytochrome P450 | 0.00002221 | DIRECT |
| MAPEG domain-like | 0.0001164 | DIRECT |
| Integrin domains | 0.000684 | DIRECT |
| Calcium-dependent phosphotriesterase | 0.000762 | DIRECT |
| Heme-dependent peroxidases | 0.001182 | INHERITED FROM: Arachidonic Acid || Arachidonic Acids |
| 4-helical cytokines | 0.001322 | INHERITED FROM: Dinoprostone || Leukotriene D4 || 15-deoxy-delta(12,14)-prostaglandin J2 |
| Cystine-knot cytokines | 0.002505 | INHERITED FROM: Dinoprostone |
| ABC transporter transmembrane region | 0.002597 | INHERITED FROM: Leukotriene C4 || SRS-A |
| Interleukin 8-like chemokines | 0.005782 | INHERITED FROM: Prostaglandins || Dinoprostone |
| Metalloproteases ("zincins"), catalytic domain | 0.0354 | INHERITED FROM: anandamide || methanandamide |
| Hemopexin-like domain | 0.04537 | INHERITED FROM: anandamide || methanandamide |
| PGBD-like | 0.04537 | INHERITED FROM: anandamide || methanandamide |
| Kringle-like | 0.08221 | INHERITED FROM: Prostaglandins || 15-deoxyprostaglandin J2 |
| Arginase/deacetylase | 0.09945 | INHERITED FROM: Prostaglandins D || Prostaglandins || 15-deoxy-delta(12,14)-prostaglandin J2 |
| Cytokine | 0.1034 | INHERITED FROM: Dinoprostone |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.1034 | INHERITED FROM: Arachidonic Acid || Arachidonic Acids || 15-hydroxy-5,8,11,13-eicosatetraenoic acid || Hydroxyeicosatetraenoic Acids || Prostaglandins B |
| Nuclear receptor ligand-binding domain | 0.1042 | INHERITED FROM: Arachidonic Acid || Dinoprostone |
| p53-like transcription factors | 0.1274 | INHERITED FROM: 15-deoxy-delta(12,14)-prostaglandin J2 |
| Thioredoxin-like | 0.1415 | INHERITED FROM: 9-deoxy-delta-9-prostaglandin D2 || Prostaglandins A |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0.1435 | INHERITED FROM: Arachidonic Acid |
| Bcl-2 inhibitors of programmed cell death | 0.1676 | INHERITED FROM: clavulone II || Prostaglandins A || Arachidonic Acids |
| Cyclin-like | 0.1897 | INHERITED FROM: Prostaglandins |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.2253 | INHERITED FROM: Arachidonic Acid |
| Inhibitor of apoptosis (IAP) repeat | 0.2397 | INHERITED FROM: Prostaglandins D || Prostaglandins || 15-deoxy-delta(12,14)-prostaglandin J2 |
| DEATH domain | 0.2631 | INHERITED FROM: 15-deoxy-delta(12,14)-prostaglandin J2 |
| Caspase-like | 0.3859 | INHERITED FROM: Arachidonic Acid || Prostaglandins D || Prostaglandins || clavulone II || Prostaglandins A || 15-deoxy-delta(12,14)-prostaglandin J2 |
| alpha/beta-Hydrolases | 0.6501 | INHERITED FROM: prostaglandin E2 glyceryl ester || Prostaglandins F |
| P-loop containing nucleoside triphosphate hydrolases | 1 | INHERITED FROM: isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate |
LINKTO: Domain2BO Download and Domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Family( show details)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | DIRECT |
| Glutathione S-transferase (GST), C-terminal domain | 0.0000001725 | DIRECT |
| Animal lipoxigenases | 0.000002491 | DIRECT |
| Glutathione S-transferase (GST), N-terminal domain | 0.00000537 | DIRECT |
| Cytochrome P450 | 0.0000785 | DIRECT |
| Lipoxigenase N-terminal domain | 0.0003122 | DIRECT |
| Integrin domains | 0.001064 | INHERITED FROM: Arachidonic Acids |
| Myeloperoxidase-like | 0.001514 | INHERITED FROM: Arachidonic Acid || Arachidonic Acids |
| Histone deacetylase, HDAC | 0.002224 | INHERITED FROM: Prostaglandins D || Prostaglandins || 15-deoxy-delta(12,14)-prostaglandin J2 |
| Gonadodropin/Follitropin | 0.002224 | INHERITED FROM: Prostaglandins |
| Fibronectin type II module | 0.003115 | INHERITED FROM: Prostaglandins |
| ABC transporter transmembrane region | 0.006434 | INHERITED FROM: Leukotriene C4 || SRS-A |
| Interleukin 8-like chemokines | 0.007421 | INHERITED FROM: Prostaglandins || Dinoprostone |
| ABC transporter ATPase domain-like | 0.01916 | INHERITED FROM: Leukotriene C4 || SRS-A |
| Hemopexin-like domain | 0.05033 | INHERITED FROM: anandamide || methanandamide |
| Short-chain cytokines | 0.05033 | INHERITED FROM: Dinoprostone || Prostaglandins E |
| MMP N-terminal domain | 0.05033 | INHERITED FROM: anandamide || methanandamide |
| Platelet-derived growth factor-like | 0.05286 | INHERITED FROM: Dinoprostone || Prostaglandins E |
| Interferons/interleukin-10 (IL-10) | 0.05286 | INHERITED FROM: Prostaglandins || Dinoprostone || Prostaglandins E |
| Rel/Dorsal transcription factors, DNA-binding domain | 0.05286 | INHERITED FROM: Arachidonic Acids |
| Long-chain cytokines | 0.05286 | INHERITED FROM: Prostaglandins || Dinoprostone |
| Nuclear receptor | 0.0928 | INHERITED FROM: Arachidonic Acid || Dinoprostone |
| Acetylcholinesterase-like | 0.1015 | INHERITED FROM: Prostaglandins |
| Interleukin-1 (IL-1) | 0.1015 | INHERITED FROM: Prostaglandins || Dinoprostone || Prostaglandins E |
| UDPGT-like | 0.1128 | INHERITED FROM: Arachidonic Acid || Arachidonic Acids || 15-hydroxy-5,8,11,13-eicosatetraenoic acid || Hydroxyeicosatetraenoic Acids || Prostaglandins B |
| Matrix metalloproteases, catalytic domain | 0.1128 | INHERITED FROM: anandamide || methanandamide |
| Nuclear receptor ligand-binding domain | 0.1306 | INHERITED FROM: Arachidonic Acid || Dinoprostone |
| NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0.1493 | INHERITED FROM: Arachidonic Acids |
| Bcl-2 inhibitors of programmed cell death | 0.1779 | INHERITED FROM: clavulone II || Prostaglandins A || Arachidonic Acids |
| Cyclin | 0.1957 | INHERITED FROM: Prostaglandins |
| Inhibitor of apoptosis (IAP) repeat | 0.2456 | INHERITED FROM: Prostaglandins D || Prostaglandins || 15-deoxy-delta(12,14)-prostaglandin J2 |
| Caspase catalytic domain | 0.2714 | INHERITED FROM: Arachidonic Acid || Prostaglandins D || Prostaglandins || clavulone II || Prostaglandins A || 15-deoxy-delta(12,14)-prostaglandin J2 |
| EGF-type module | 0.2976 | INHERITED FROM: Prostaglandins || Dinoprostone |
LINKTO: Domain2BO Download and Domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Single)( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Lipoxigenase | 0.0000008633 | DIRECT |
| GST C-terminal domain-like | 0.000001067 | DIRECT |
| Cytochrome P450 | 0.00001123 | DIRECT |
| MAPEG domain-like | 0.00006273 | DIRECT |
| Integrin domains | 0.0004006 | DIRECT |
| Calcium-dependent phosphotriesterase | 0.0004488 | DIRECT |
| Heme-dependent peroxidases | 0.0007118 | DIRECT |
| 4-helical cytokines | 0.0008011 | DIRECT |
| Cystine-knot cytokines | 0.001565 | INHERITED FROM: Dinoprostone |
| ABC transporter transmembrane region | 0.001626 | INHERITED FROM: SRS-A || Leukotriene C4 |
| Interleukin 8-like chemokines | 0.003775 | INHERITED FROM: Prostaglandins || Dinoprostone |
| Metalloproteases ("zincins"), catalytic domain | 0.02569 | INHERITED FROM: anandamide || methanandamide |
| Hemopexin-like domain | 0.0334 | INHERITED FROM: anandamide || methanandamide |
| PGBD-like | 0.0334 | INHERITED FROM: anandamide || methanandamide |
| Kringle-like | 0.06255 | INHERITED FROM: Prostaglandins || Dinoprostone || 15-deoxyprostaglandin J2 |
| Arginase/deacetylase | 0.07644 | INHERITED FROM: Prostaglandins || 15-deoxy-delta(12,14)-prostaglandin J2 || Prostaglandins D |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.07961 | INHERITED FROM: Arachidonic Acid || Arachidonic Acids || 15-hydroxy-5,8,11,13-eicosatetraenoic acid || Hydroxyeicosatetraenoic Acids || Prostaglandins B |
| Cytokine | 0.07961 | INHERITED FROM: Dinoprostone |
| Nuclear receptor ligand-binding domain | 0.0803 | INHERITED FROM: Arachidonic Acid || Dinoprostone |
| p53-like transcription factors | 0.09924 | INHERITED FROM: 15-deoxy-delta(12,14)-prostaglandin J2 |
| Thioredoxin-like | 0.111 | INHERITED FROM: Prostaglandins A || 9-deoxy-delta-9-prostaglandin D2 |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0.1126 | INHERITED FROM: Arachidonic Acid |
| Bcl-2 inhibitors of programmed cell death | 0.1328 | INHERITED FROM: Arachidonic Acids || clavulone II || Prostaglandins A |
| Cyclin-like | 0.1517 | INHERITED FROM: Prostaglandins |
| Leucine zipper domain | 0.1573 | INHERITED FROM: Dinoprostone |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.1826 | INHERITED FROM: Arachidonic Acid || Dinoprostone |
| Inhibitor of apoptosis (IAP) repeat | 0.195 | INHERITED FROM: Prostaglandins || 15-deoxy-delta(12,14)-prostaglandin J2 || Prostaglandins D |
| DEATH domain | 0.2155 | INHERITED FROM: 15-deoxy-delta(12,14)-prostaglandin J2 |
| Caspase-like | 0.3258 | INHERITED FROM: Prostaglandins || Arachidonic Acid || clavulone II || 15-deoxy-delta(12,14)-prostaglandin J2 || Prostaglandins A || Prostaglandins D |
| alpha/beta-Hydrolases | 0.5785 | INHERITED FROM: prostaglandin E2 glyceryl ester || Prostaglandins F |
| P-loop containing nucleoside triphosphate hydrolases | 0.9556 | INHERITED FROM: isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Duplex) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
52833,47616 52833 - Thioredoxin-like 47616 - GST C-terminal domain-like | 0.0000000313 | DIRECT |
49723,48484 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain) 48484 - Lipoxigenase | 0.0000008633 | DIRECT |
47986,47986 47986 - DEATH domain 47986 - DEATH domain | 0.0001384 | DIRECT |
52540,90123 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0.0004488 | DIRECT |
90123,52540 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.001626 | INHERITED FROM: SRS-A || Leukotriene C4 |
81324,81324 81324 - Voltage-gated potassium channels 81324 - Voltage-gated potassium channels | 0.002793 | INHERITED FROM: Arachidonic Acid || Arachidonic Acids |
69318,69179 69318 - Integrin alpha N-terminal domain 69179 - Integrin domains | 0.007084 | INHERITED FROM: Arachidonic Acids |
69179,69179 69179 - Integrin domains 69179 - Integrin domains | 0.007084 | INHERITED FROM: Arachidonic Acids |
57440,57440 57440 - Kringle-like 57440 - Kringle-like | 0.01763 | INHERITED FROM: Prostaglandins || Dinoprostone || 15-deoxyprostaglandin J2 |
47090,55486 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain | 0.0334 | INHERITED FROM: anandamide || methanandamide |
47954,47954 47954 - Cyclin-like 47954 - Cyclin-like | 0.0334 | INHERITED FROM: Prostaglandins |
49417,81296 49417 - p53-like transcription factors 81296 - E set domains | 0.03721 | INHERITED FROM: Arachidonic Acids |
57716,48508 57716 - Glucocorticoid receptor-like (DNA-binding domain) 48508 - Nuclear receptor ligand-binding domain | 0.07576 | INHERITED FROM: Arachidonic Acid |
57924,57924 57924 - Inhibitor of apoptosis (IAP) repeat 57924 - Inhibitor of apoptosis (IAP) repeat | 0.07644 | INHERITED FROM: Prostaglandins || 15-deoxy-delta(12,14)-prostaglandin J2 || Prostaglandins D |
47986,52129 47986 - DEATH domain 52129 - Caspase-like | 0.195 | INHERITED FROM: Prostaglandins || 15-deoxy-delta(12,14)-prostaglandin J2 || Prostaglandins D |
48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin | 0.7939 | INHERITED FROM: Lipoxins |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
52833,47616 52833 - Thioredoxin-like 47616 - GST C-terminal domain-like | 0.0000000313 | Direct |
49723,48484 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain) 48484 - Lipoxigenase | 0.0000008633 | Direct |
47986,47986 47986 - DEATH domain 47986 - DEATH domain | 0.0001384 | Direct |
52540,90123 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0.0004488 | Direct |
90123,52540 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.001626 | Inherited |
81324,81324 81324 - Voltage-gated potassium channels 81324 - Voltage-gated potassium channels | 0.002793 | Inherited |
69318,69179 69318 - Integrin alpha N-terminal domain 69179 - Integrin domains | 0.007084 | Inherited |
69179,69179 69179 - Integrin domains 69179 - Integrin domains | 0.007084 | Inherited |
57440,57440 57440 - Kringle-like 57440 - Kringle-like | 0.01763 | Inherited |
47090,55486 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain | 0.0334 | Inherited |
47954,47954 47954 - Cyclin-like 47954 - Cyclin-like | 0.0334 | Inherited |
49417,81296 49417 - p53-like transcription factors 81296 - E set domains | 0.03721 | Inherited |
57716,48508 57716 - Glucocorticoid receptor-like (DNA-binding domain) 48508 - Nuclear receptor ligand-binding domain | 0.07576 | Inherited |
57924,57924 57924 - Inhibitor of apoptosis (IAP) repeat 57924 - Inhibitor of apoptosis (IAP) repeat | 0.07644 | Inherited |
47986,52129 47986 - DEATH domain 52129 - Caspase-like | 0.195 | Inherited |
48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin | 0.7939 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Triple) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
57924,57924,57924 57924 - Inhibitor of apoptosis (IAP) repeat 57924 - Inhibitor of apoptosis (IAP) repeat 57924 - Inhibitor of apoptosis (IAP) repeat | 0.00000472 | DIRECT |
57440,57440,57440 57440 - Kringle-like 57440 - Kringle-like 57440 - Kringle-like | 0.0001384 | DIRECT |
52540,90123,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.0004488 | DIRECT |
90123,52540,90123 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0.0004488 | DIRECT |
69179,69179,69179 69179 - Integrin domains 69179 - Integrin domains 69179 - Integrin domains | 0.004627 | INHERITED FROM: Arachidonic Acids |
69318,69179,69179 69318 - Integrin alpha N-terminal domain 69179 - Integrin domains 69179 - Integrin domains | 0.007084 | INHERITED FROM: Arachidonic Acids |
48726,48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin 48726 - Immunoglobulin | 0.5624 | INHERITED FROM: Lipoxins |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
57924,57924,57924 57924 - Inhibitor of apoptosis (IAP) repeat 57924 - Inhibitor of apoptosis (IAP) repeat 57924 - Inhibitor of apoptosis (IAP) repeat | 0.00000472 | Direct |
57440,57440,57440 57440 - Kringle-like 57440 - Kringle-like 57440 - Kringle-like | 0.0001384 | Direct |
52540,90123,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.0004488 | Direct |
90123,52540,90123 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0.0004488 | Direct |
69179,69179,69179 69179 - Integrin domains 69179 - Integrin domains 69179 - Integrin domains | 0.004627 | Inherited |
69318,69179,69179 69318 - Integrin alpha N-terminal domain 69179 - Integrin domains 69179 - Integrin domains | 0.007084 | Inherited |
48726,48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin 48726 - Immunoglobulin | 0.5624 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Plot distribution on species Tree Of Life (sTOL) for Superfamily and/or Family domains annotated by this CC term
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Plot tree as:
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Download Newick format tree:
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( show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domain
architecture data for all genomes in SUPERFAMILY. The PAUP
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
Plot distribution on species Tree Of Life (sTOL) for single supra-domains annotated by this CC term
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Plot tree as:
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Download Newick format tree:
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Browsing in TREE OF LIFE:
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( show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
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