Mammalian Phenotype (MP): abnormal blood vessel morphology 

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children)	MP term [MP ID] <#Children>	#Domains (Superfamily|Family)	#Supra-domain (Single|Duplex|Triple)
+ + + 3:	mammalian phenotype [MP:0000001] <29>
+ + 2:	cardiovascular system phenotype [MP:0005385] <2>	(67|85)	(77|57|35)
+ 1:	abnormal cardiovascular system morphology [MP:0002127] <7>	(48|65)	(53|44|33)
0:	abnormal blood vessel morphology [MP:0001614] <29>	(31|38)	(36|27|24)
- 1:	abnormal vein morphology [MP:0002725] <17>	(2|2)	(2|4|2)
- 1:	abnormal artery morphology [MP:0002191] <10>	(17|20)	(19|16|17)
- 1:	abnormal vascular development [MP:0000259] <9>	(13|24)	(18|13|5)
- 1:	abnormal kidney blood vessel morphology [MP:0000530] <7>	(5|5)	(5|0|0)
- 1:	abnormal capillary morphology [MP:0003658] <6>	(5|5)	(5|0|0)
- 1:	abnormal vascular smooth muscle morphology [MP:0005592] <6>	(0|0)	(1|1|0)
- 1:	abnormal blood vessel endothelium morphology [MP:0009489] <4>	(0|1)	(0|0|0)
- 1:	abnormal retinal vasculature morphology [MP:0002792] <4>	(4|3)	(4|3|1)
- 1:	arteriovenous malformation [MP:0006093] <4>	(0|0)	(0|1|1)
- 1:	vasculature congestion [MP:0000255] <4>	(4|5)	(4|0|1)
- 1:	abnormal intersomitic vessel morphology [MP:0012253] <3>	(1|0)	(2|0|0)
- 1:	abnormal liver vasculature morphology [MP:0009820] <3>	(4|4)	(4|0|0)
- 1:	abnormal lung vasculature morphology [MP:0004007] <3>	(4|4)	(4|0|0)
- 1:	vascular stenosis [MP:0005412] <3>	(0|0)	(0|0|1)
- 1:	abnormal choroid vasculature morphology [MP:0006237] <2>	(3|2)	(3|2|1)
- 1:	abnormal placenta vasculature [MP:0003231] <2>	(1|2)	(1|0|0)
- 1:	abnormal blood vessel elastic tissue morphology [MP:0006083] <1>	(0|2)	(0|3|2)
- 1:	abnormal conjunctival vasculature morphology [MP:0006192] <1>	(0|0)	(0|0|0)
- 1:	abnormal cranial blood vasculature morphology [MP:0014012] <1>	(0|0)	(0|0|0)
- 1:	dilated vasculature [MP:0004938] <1>	(0|1)	(0|0|0)
- 1:	abnormal pericyte morphology [MP:0003719]	(0|0)	(0|0|0)
- 1:	abnormal perivascular macrophage morphology [MP:0008242]	(0|0)	(0|0|0)
- 1:	abnormal stria vascularis vasculature morphology [MP:0004368]	(0|0)	(0|0|0)
- 1:	abnormal urinary bladder blood vessel morphology [MP:0011773]	(0|0)	(0|0|0)
- 1:	atretic vasculature [MP:0000265]	(0|0)	(0|0|0)
- 1:	hemangioma [MP:0014086]	(0|0)	(0|0|0)
- 1:	perivascular fibrosis [MP:0011749]	(4|4)	(4|0|0)
- 1:	vascular diverticulum [MP:0013869]	(0|0)	(0|0|0)
- 1:	vasculature degeneration [MP:0012562]	(0|0)	(0|0|0)

Superfamily

Highlighted in gray are those with FDR_all>0.001

SCOP term	FDR (all)	Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain	0	DIRECT
EGF/Laminin	0.0000146	DIRECT
Calcium-dependent phosphotriesterase	0.0001678	DIRECT
Integrin beta tail domain	0.000756	DIRECT
Notch domain	0.0008755	DIRECT
FnI-like domain	0.005379	INHERITED FROM: abnormal angiogenesis
YWTD domain	0.0107	INHERITED FROM: abnormal systemic artery morphology || abnormal aorta morphology
Cytokine	0.01573	INHERITED FROM: aberrant origin of the right subclavian artery || abnormal right subclavian artery morphology || abnormal aortic arch and aortic arch branch attachment
Integrin domains	0.02221	INHERITED FROM: abnormal glomerular capillary morphology
Growth factor receptor domain	0.02947	INHERITED FROM: abnormal cardinal vein morphology || abnormal aorta morphology || abnormal aorta tunica media morphology
p53-like transcription factors	0.03407	INHERITED FROM: abnormal vascular development
Tetraspanin	0.05046	INHERITED FROM: abnormal retinal vasculature morphology
PYP-like sensor domain (PAS domain)	0.06155	INHERITED FROM: abnormal vascular regression
PGBD-like	0.08535	INHERITED FROM: abnormal induced retinal neovascularization || decreased angiogenesis || retinal neovascularization || aortic aneurysm
Hemopexin-like domain	0.1172	INHERITED FROM: decreased angiogenesis || aortic aneurysm
Metalloproteases ("zincins"), catalytic domain	0.1707	INHERITED FROM: retinal neovascularization || decreased susceptibility to induced choroidal neovascularization
Homeodomain-like	0.1889	INHERITED FROM: abnormal stapedial artery morphology || retroesophageal right subclavian artery || abnormal right subclavian artery morphology
TB module/8-cys domain	0.2189	INHERITED FROM: abnormal systemic artery morphology || abnormal artery morphology || abnormal aorta morphology || abnormal aorta tunica media morphology
Nuclear receptor ligand-binding domain	0.2361	INHERITED FROM: abnormal stapedial artery morphology || absent fetal ductus arteriosus || persistent right dorsal aorta || altered susceptibility to atherosclerosis
Glucocorticoid receptor-like (DNA-binding domain)	0.2926	INHERITED FROM: absent fetal ductus arteriosus
Interleukin 8-like chemokines	0.2954	INHERITED FROM: decreased susceptibility to atherosclerosis || atherosclerotic lesions || altered susceptibility to atherosclerosis
Kringle-like	0.2954	INHERITED FROM: decreased susceptibility to atherosclerosis || abnormal choroid vasculature morphology || atherosclerotic lesions || choroidal neovascularization || decreased susceptibility to induced choroidal neovascularization
Flavoproteins	0.2976	INHERITED FROM: abnormal liver vasculature morphology || abnormal kidney blood vessel morphology || vasculature congestion || abnormal lung vasculature morphology || abnormal capillary morphology || glomerular capillary thrombosis || visceral vascular congestion || abnormal coronary artery morphology || pulmonary vascular congestion || perivascular fibrosis || arteriosclerosis || abnormal glomerular capillary morphology || liver vascular congestion || abnormal kidney thrombosis || abnormal kidney capillary morphology
Riboflavin synthase domain-like	0.3449	INHERITED FROM: abnormal artery morphology || glomerular capillary thrombosis || visceral vascular congestion || pulmonary vascular congestion || perivascular fibrosis || abnormal glomerular capillary morphology || liver vascular congestion || abnormal kidney thrombosis || abnormal kidney capillary morphology
Ferredoxin reductase-like, C-terminal NADP-linked domain	0.3449	INHERITED FROM: abnormal artery morphology || glomerular capillary thrombosis || visceral vascular congestion || pulmonary vascular congestion || perivascular fibrosis || abnormal glomerular capillary morphology || liver vascular congestion || abnormal kidney thrombosis || abnormal kidney capillary morphology
Frizzled cysteine-rich domain	0.3619	INHERITED FROM: disorganized yolk sac vascular plexus
E set domains	0.3676	INHERITED FROM: abnormal intersomitic vessel morphology
Snake toxin-like	0.3686	INHERITED FROM: abnormal aortic arch morphology
SH3-domain	0.4816	INHERITED FROM: abnormal vascular endothelial cell development
Trypsin-like serine proteases	0.7562	INHERITED FROM: choroidal neovascularization || decreased susceptibility to induced choroidal neovascularization
Protein kinase-like (PK-like)	0.9538	INHERITED FROM: abnormal placenta vasculature

Family

Highlighted in gray are those with FDR_all>0.001

SCOP term	FDR (all)	Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain	0	DIRECT
Interleukin-1 (IL-1)	0	DIRECT
Integrin beta EGF-like domains	0.000114	DIRECT
Integrin beta tail domain	0.0005412	DIRECT
Pointed domain	0.0005412	DIRECT
Notch domain	0.0006104	DIRECT
EGF-type module	0.001066	INHERITED FROM: abnormal cardinal vein morphology || abnormal aorta elastic fiber morphology || abnormal vascular plexus formation || abnormal aorta morphology || abnormal aorta tunica media morphology
Erythroid transcription factor GATA-1	0.001528	INHERITED FROM: abnormal systemic artery morphology || abnormal aorta morphology || abnormal thoracic aorta morphology
Hypoxia-inducible factor Hif2a, C-terminal domain	0.001804	INHERITED FROM: abnormal vascular regression
YWTD domain	0.008838	INHERITED FROM: abnormal systemic artery morphology || abnormal aorta morphology || abnormal descending aorta morphology
ets domain	0.01378	INHERITED FROM: abnormal vascular endothelial cell morphology || abnormal vascular development
Integrin domains	0.01783	INHERITED FROM: abnormal glomerular capillary morphology
Forkhead DNA-binding domain	0.01886	INHERITED FROM: abnormal aortic arch morphology
Transforming growth factor (TGF)-beta	0.04725	INHERITED FROM: absent vitelline blood vessels
MMP N-terminal domain	0.07178	INHERITED FROM: abnormal induced retinal neovascularization || decreased angiogenesis || retinal neovascularization || aortic aneurysm
Fibroblast growth factors (FGF)	0.07178	INHERITED FROM: aberrant origin of the right subclavian artery || abnormal subclavian artery morphology || abnormal right subclavian artery morphology || abnormal aortic arch and aortic arch branch attachment
Matrix metalloproteases, catalytic domain	0.07178	INHERITED FROM: abnormal induced retinal neovascularization || decreased angiogenesis || retinal neovascularization || aortic aneurysm
Linker histone H1/H5	0.07842	INHERITED FROM: absent vitelline blood vessels || abnormal vitelline vasculature morphology
Hemopexin-like domain	0.1009	INHERITED FROM: decreased angiogenesis || aortic aneurysm
DBL homology domain (DH-domain)	0.1218	INHERITED FROM: abnormal vascular endothelial cell migration
Homeodomain	0.1253	INHERITED FROM: abnormal systemic artery morphology || retroesophageal right subclavian artery
ZZ domain	0.1953	INHERITED FROM: abnormal vitelline vasculature morphology
TB module/8-cys domain	0.1953	INHERITED FROM: abnormal systemic artery morphology || abnormal artery morphology || abnormal aorta morphology || abnormal aorta tunica media morphology
Nuclear receptor ligand-binding domain	0.2262	INHERITED FROM: abnormal stapedial artery morphology || absent fetal ductus arteriosus || persistent right dorsal aorta || altered susceptibility to atherosclerosis
Nuclear receptor	0.2262	INHERITED FROM: abnormal stapedial artery morphology || absent fetal ductus arteriosus || persistent right dorsal aorta || altered susceptibility to atherosclerosis
Fibronectin type III	0.2282	INHERITED FROM: absent organized vascular network
NADPH-cytochrome p450 reductase-like	0.2715	INHERITED FROM: abnormal liver vasculature morphology || abnormal artery morphology || abnormal kidney blood vessel morphology || vasculature congestion || abnormal lung vasculature morphology || abnormal capillary morphology || glomerular capillary thrombosis || visceral vascular congestion || abnormal coronary artery morphology || pulmonary vascular congestion || perivascular fibrosis || abnormal angiogenesis || arteriosclerosis || abnormal glomerular capillary morphology || liver vascular congestion || abnormal kidney thrombosis || abnormal kidney capillary morphology
NADPH-cytochrome p450 reductase FAD-binding domain-like	0.2715	INHERITED FROM: abnormal liver vasculature morphology || abnormal artery morphology || abnormal kidney blood vessel morphology || vasculature congestion || abnormal lung vasculature morphology || abnormal capillary morphology || glomerular capillary thrombosis || visceral vascular congestion || abnormal coronary artery morphology || pulmonary vascular congestion || perivascular fibrosis || abnormal angiogenesis || arteriosclerosis || abnormal glomerular capillary morphology || liver vascular congestion || abnormal kidney thrombosis || abnormal kidney capillary morphology
Cytochrome p450 reductase N-terminal domain-like	0.2715	INHERITED FROM: abnormal liver vasculature morphology || abnormal artery morphology || abnormal kidney blood vessel morphology || vasculature congestion || abnormal lung vasculature morphology || abnormal capillary morphology || glomerular capillary thrombosis || visceral vascular congestion || abnormal coronary artery morphology || pulmonary vascular congestion || perivascular fibrosis || abnormal angiogenesis || arteriosclerosis || abnormal glomerular capillary morphology || liver vascular congestion || abnormal kidney thrombosis || abnormal kidney capillary morphology
Interleukin 8-like chemokines	0.2874	INHERITED FROM: decreased susceptibility to atherosclerosis || atherosclerotic lesions || altered susceptibility to atherosclerosis
Growth factor receptor domain	0.3106	INHERITED FROM: abnormal cardinal vein morphology || abnormal aorta elastic fiber morphology || abnormal aorta morphology || abnormal aorta tunica media morphology
Kringle modules	0.3222	INHERITED FROM: abnormal choroid vasculature morphology || choroidal neovascularization || decreased susceptibility to induced choroidal neovascularization
Frizzled cysteine-rich domain	0.343	INHERITED FROM: disorganized yolk sac vascular plexus
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain	0.4106	INHERITED FROM: abnormal dorsal aorta morphology || abnormal placental labyrinth vasculature morphology
Eukaryotic proteases	0.4183	INHERITED FROM: abnormal choroid vasculature morphology || choroidal neovascularization || decreased susceptibility to induced choroidal neovascularization
SH3-domain	0.5234	INHERITED FROM: abnormal vascular endothelial cell development
LIM domain	0.8368	INHERITED FROM: vasculature congestion || visceral vascular congestion
Protein kinases, catalytic subunit	0.8915	INHERITED FROM: abnormal placenta vasculature

Supra-domain (Single|Duplex|Triple)

Supra-domain (Single)

Highlighted in gray are those with FDR>0.001

Supra-domain (Single)	FDR (all)	Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain	0	DIRECT
EGF/Laminin	0.000006487	DIRECT
Calcium-dependent phosphotriesterase	0.00008416	DIRECT
Integrin beta tail domain	0.0004063	DIRECT
Notch domain	0.0004738	DIRECT
FnI-like domain	0.003231	INHERITED FROM: abnormal angiogenesis
YWTD domain	0.006714	INHERITED FROM: abnormal systemic artery morphology || abnormal aorta morphology || abnormal descending aorta morphology
Cytokine	0.01013	INHERITED FROM: abnormal aortic arch and aortic arch branch attachment || abnormal right subclavian artery morphology || aberrant origin of the right subclavian artery
Integrin domains	0.0147	INHERITED FROM: abnormal glomerular capillary morphology || abnormal angiogenesis
Growth factor receptor domain	0.02002	INHERITED FROM: abnormal aorta morphology || abnormal cardinal vein morphology || abnormal aorta tunica media morphology
p53-like transcription factors	0.02338	INHERITED FROM: abnormal artery development || abnormal vascular development
Tetraspanin	0.03565	INHERITED FROM: abnormal retinal vasculature morphology
PYP-like sensor domain (PAS domain)	0.04444	INHERITED FROM: abnormal vascular regression
PGBD-like	0.06338	INHERITED FROM: abnormal induced retinal neovascularization || retinal neovascularization || aortic aneurysm || decreased angiogenesis
4-helical cytokines	0.07127	INHERITED FROM: atherosclerotic lesions
Hemopexin-like domain	0.09024	INHERITED FROM: aortic aneurysm || decreased angiogenesis
DBL homology domain (DH-domain)	0.09636	INHERITED FROM: abnormal vascular endothelial cell migration
Metalloproteases ("zincins"), catalytic domain	0.1367	INHERITED FROM: retinal neovascularization || decreased susceptibility to induced choroidal neovascularization
Homeodomain-like	0.1532	INHERITED FROM: abnormal right subclavian artery morphology || abnormal stapedial artery morphology || abnormal aortic arch morphology || retroesophageal right subclavian artery
Fibronectin type III	0.1668	INHERITED FROM: absent organized vascular network
TB module/8-cys domain	0.1807	INHERITED FROM: abnormal systemic artery morphology || abnormal aorta morphology || abnormal artery morphology || abnormal aorta tunica media morphology
Nuclear receptor ligand-binding domain	0.1968	INHERITED FROM: absent fetal ductus arteriosus || abnormal stapedial artery morphology || altered susceptibility to atherosclerosis || persistent right dorsal aorta
Glucocorticoid receptor-like (DNA-binding domain)	0.2498	INHERITED FROM: absent fetal ductus arteriosus
Kringle-like	0.2524	INHERITED FROM: choroidal neovascularization || decreased susceptibility to induced choroidal neovascularization || decreased susceptibility to atherosclerosis || abnormal choroid vasculature morphology || atherosclerotic lesions
Interleukin 8-like chemokines	0.2524	INHERITED FROM: decreased susceptibility to atherosclerosis || altered susceptibility to atherosclerosis || atherosclerotic lesions
Flavoproteins	0.2544	INHERITED FROM: vasculature congestion || abnormal liver vasculature morphology || abnormal glomerular capillary morphology || abnormal kidney capillary morphology || abnormal coronary artery morphology || abnormal kidney blood vessel morphology || arteriosclerosis || glomerular capillary thrombosis || abnormal kidney thrombosis || abnormal capillary morphology || perivascular fibrosis || visceral vascular congestion || abnormal lung vasculature morphology || liver vascular congestion || pulmonary vascular congestion
Riboflavin synthase domain-like	0.2995	INHERITED FROM: abnormal liver vasculature morphology || abnormal glomerular capillary morphology || abnormal kidney capillary morphology || glomerular capillary thrombosis || abnormal kidney thrombosis || abnormal artery morphology || perivascular fibrosis || visceral vascular congestion || liver vascular congestion || pulmonary vascular congestion
Ferredoxin reductase-like, C-terminal NADP-linked domain	0.2995	INHERITED FROM: abnormal liver vasculature morphology || abnormal glomerular capillary morphology || abnormal kidney capillary morphology || glomerular capillary thrombosis || abnormal kidney thrombosis || abnormal artery morphology || perivascular fibrosis || visceral vascular congestion || liver vascular congestion || pulmonary vascular congestion
Frizzled cysteine-rich domain	0.3162	INHERITED FROM: disorganized yolk sac vascular plexus
E set domains	0.3217	INHERITED FROM: abnormal intersomitic vessel morphology
Snake toxin-like	0.3228	INHERITED FROM: abnormal pharyngeal arch artery morphology || abnormal aortic arch morphology
Ankyrin repeat	0.4274	INHERITED FROM: abnormal intersomitic vessel morphology
SH3-domain	0.4339	INHERITED FROM: abnormal vascular endothelial cell development
Trypsin-like serine proteases	0.7182	INHERITED FROM: choroidal neovascularization || decreased susceptibility to induced choroidal neovascularization || abnormal choroid vasculature morphology
PH domain-like	0.8454	INHERITED FROM: abnormal vascular endothelial cell development
Protein kinase-like (PK-like)	0.9328	INHERITED FROM: abnormal placenta vasculature

Supra-domain (Duplex) in N- to C-terminal order

Highlighted in gray are those with FDR>0.001

Supra-domain (Duplex) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
57196,90193 57196 - EGF/Laminin 90193 - Notch domain	0	DIRECT
90193,90193 90193 - Notch domain 90193 - Notch domain	0	DIRECT
57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin	0.000000639	DIRECT
57196,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain	0.00000118	DIRECT
57440,57440 57440 - Kringle-like 57440 - Kringle-like	0.000002153	DIRECT
55550,50044 55550 - SH2 domain 50044 - SH3-domain	0.0002654	DIRECT
53300,69179 53300 - vWA-like 69179 - Integrin domains	0.0004063	DIRECT
57603,57603 57603 - FnI-like domain 57603 - FnI-like domain	0.0004063	DIRECT
57196,69687 57196 - EGF/Laminin 69687 - Integrin beta tail domain	0.0004063	DIRECT
57440,50494 57440 - Kringle-like 50494 - Trypsin-like serine proteases	0.001156	INHERITED FROM: choroidal neovascularization || decreased susceptibility to induced choroidal neovascularization || abnormal choroid vasculature morphology
57196,57581 57196 - EGF/Laminin 57581 - TB module/8-cys domain	0.001888	INHERITED FROM: abnormal systemic artery morphology || abnormal aorta morphology || abnormal artery morphology || abnormal aorta tunica media morphology
57581,57196 57581 - TB module/8-cys domain 57196 - EGF/Laminin	0.001888	INHERITED FROM: abnormal systemic artery morphology || abnormal aorta morphology || abnormal artery morphology || abnormal aorta tunica media morphology
49785,57184 49785 - Galactose-binding domain-like 57184 - Growth factor receptor domain	0.002577	INHERITED FROM: abnormal angiogenesis
63825,57196 63825 - YWTD domain 57196 - EGF/Laminin	0.002577	INHERITED FROM: abnormal systemic artery morphology || abnormal aorta morphology || abnormal descending aorta morphology
57424,57184 57424 - LDL receptor-like module 57184 - Growth factor receptor domain	0.0047	INHERITED FROM: abnormal systemic artery morphology || abnormal aorta morphology
57184,63825 57184 - Growth factor receptor domain 63825 - YWTD domain	0.0047	INHERITED FROM: abnormal systemic artery morphology || abnormal aorta morphology
47459,55785 47459 - HLH, helix-loop-helix DNA-binding domain 55785 - PYP-like sensor domain (PAS domain)	0.005207	INHERITED FROM: abnormal vascular regression
57184,57196 57184 - Growth factor receptor domain 57196 - EGF/Laminin	0.01013	INHERITED FROM: abnormal aorta morphology || abnormal blood vessel elastic tissue morphology || abnormal aorta elastic fiber morphology || abnormal aorta tunica media morphology
57184,57184 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain	0.02137	INHERITED FROM: abnormal aorta morphology || abnormal aorta elastic fiber morphology || abnormal aorta tunica media morphology
57716,48508 57716 - Glucocorticoid receptor-like (DNA-binding domain) 48508 - Nuclear receptor ligand-binding domain	0.055	INHERITED FROM: absent fetal ductus arteriosus || abnormal stapedial artery morphology || abnormal pharyngeal arch artery morphology || right aortic arch || persistent right dorsal aorta
47090,55486 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain	0.06338	INHERITED FROM: abnormal induced retinal neovascularization || retinal neovascularization || aortic aneurysm || decreased angiogenesis
48065,50729 48065 - DBL homology domain (DH-domain) 50729 - PH domain-like	0.07711	INHERITED FROM: abnormal vascular endothelial cell migration
49854,49854 49854 - Spermadhesin, CUB domain 49854 - Spermadhesin, CUB domain	0.128	INHERITED FROM: abnormal dorsal aorta morphology
57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module	0.2297	INHERITED FROM: abnormal systemic artery morphology || abnormal aorta morphology
48726,49265 48726 - Immunoglobulin 49265 - Fibronectin type III	0.2524	INHERITED FROM: absent organized vascular network
49265,49265 49265 - Fibronectin type III 49265 - Fibronectin type III	0.2741	INHERITED FROM: absent organized vascular network
52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases	0.7511	INHERITED FROM: abnormal inferior vena cava morphology

Supra-domain (Triple) in N- to C-terminal order

Highlighted in gray are those with FDR>0.001

Supra-domain (Triple) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
57184,57196,57184 57184 - Growth factor receptor domain 57196 - EGF/Laminin 57184 - Growth factor receptor domain	0	DIRECT
57196,90193,90193 57196 - EGF/Laminin 90193 - Notch domain 90193 - Notch domain	0	DIRECT
57196,57184,57196 57196 - EGF/Laminin 57184 - Growth factor receptor domain 57196 - EGF/Laminin	0.0000108	DIRECT
57196,57184,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain	0.00008416	DIRECT
57603,57603,57603 57603 - FnI-like domain 57603 - FnI-like domain 57603 - FnI-like domain	0.00008416	DIRECT
57184,57196,57196 57184 - Growth factor receptor domain 57196 - EGF/Laminin 57196 - EGF/Laminin	0.00008611	DIRECT
57196,57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin 57196 - EGF/Laminin	0.0001403	DIRECT
57184,57184,57184 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain	0.0004063	DIRECT
57184,57184,57196 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain 57196 - EGF/Laminin	0.0004063	DIRECT
57196,57196,69687 57196 - EGF/Laminin 57196 - EGF/Laminin 69687 - Integrin beta tail domain	0.0004063	DIRECT
57440,57440,50494 57440 - Kringle-like 57440 - Kringle-like 50494 - Trypsin-like serine proteases	0.0004738	DIRECT
57440,57440,57440 57440 - Kringle-like 57440 - Kringle-like 57440 - Kringle-like	0.0004738	DIRECT
57196,57196,57581 57196 - EGF/Laminin 57196 - EGF/Laminin 57581 - TB module/8-cys domain	0.0004738	DIRECT
57581,57196,57196 57581 - TB module/8-cys domain 57196 - EGF/Laminin 57196 - EGF/Laminin	0.0004738	DIRECT
57196,57196,57184 57196 - EGF/Laminin 57196 - EGF/Laminin 57184 - Growth factor receptor domain	0.0007164	DIRECT
57424,57424,57184 57424 - LDL receptor-like module 57424 - LDL receptor-like module 57184 - Growth factor receptor domain	0.001888	INHERITED FROM: abnormal systemic artery morphology || abnormal aorta morphology
57424,57184,63825 57424 - LDL receptor-like module 57184 - Growth factor receptor domain 63825 - YWTD domain	0.001888	INHERITED FROM: abnormal systemic artery morphology || abnormal aorta morphology
57196,57581,57184 57196 - EGF/Laminin 57581 - TB module/8-cys domain 57184 - Growth factor receptor domain	0.002481	INHERITED FROM: abnormal systemic artery morphology || abnormal aorta morphology || abnormal artery morphology
57581,57196,57581 57581 - TB module/8-cys domain 57196 - EGF/Laminin 57581 - TB module/8-cys domain	0.008207	INHERITED FROM: abnormal systemic artery morphology || abnormal aorta morphology || abnormal artery morphology
63825,57196,63825 63825 - YWTD domain 57196 - EGF/Laminin 63825 - YWTD domain	0.01758	INHERITED FROM: abnormal systemic artery morphology || abnormal aorta morphology
48726,49265,49265 48726 - Immunoglobulin 49265 - Fibronectin type III 49265 - Fibronectin type III	0.1807	INHERITED FROM: absent organized vascular network
57424,57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module 57424 - LDL receptor-like module	0.2297	INHERITED FROM: abnormal systemic artery morphology || abnormal aorta morphology
52540,52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases	0.2544	INHERITED FROM: abnormal systemic artery morphology || abnormal aorta morphology || abnormal inferior vena cava morphology || abnormal vein morphology || abnormal vena cava morphology
57716,57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain)	0.6377	INHERITED FROM: vasculature congestion || visceral vascular congestion