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  Home > SCOP hierarchy > 2let A: PDB entry domain

2let A: PDB entry domain

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Small proteins [ 56992] (90)
Fold:   Knottins (small inhibitors, toxins, lectins) [ 57015] (19)
Superfamily:   Plant inhibitors of proteinases and amylases [ 57027]
Family:   Plant inhibitors of proteinases and amylases [ 57028] (3)
Protein:   Trypsin inhibitor [57029]
   
PDB Entry Domain:   2let A: [ 44072]
  SUPERFAMILY domain annotation for 2leta
  PDB structure summary for 2let

 InterPro annotation
Cross references IPR011052 SSF57027 Protein matches
Abstract

This family includes inhibitors of proteinases and amylases, such as trypsin inhibitors [PubMed12198301], carboxypeptidase A inhibitors [PubMed12557184], and alpha-amylase inhibitors (AAI) [PubMed11298757]. The proteins display a knottins-like (small inhibitors, toxins, lectins) disulphide-bound fold, containing a beta-hairpin with two adjacent disulphides.

More information about this protein can be found at Protein of the Month: alpha-Amylase.


InterPro database
PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.
   
Superfamily level     Family level

Alignments of sequences to 13 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Plant inhibitors of proteinases and amylases domain.
   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Internal database links ]
Please cite: Gough, J., Karplus, K., Hughey, R. and Chothia, C. (2001). "Assignment of Homology to Genome Sequences using a Library of Hidden Markov Models that Represent all Proteins of Known Structure." J. Mol. Biol., 313(4), 903-919.

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© Copyright 2013 The SUPERFAMILY authors and Julian Gough.