SUPERFAMILY 1.75 HMM library and genome assignments server

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OsmC-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   OsmC-like [ 82783]
Superfamily:   OsmC-like [ 82784] (2)
Families:   Ohr/OsmC resistance proteins [ 82785] (7)
  YhfA-like [ 90027] (2)

Superfamily statistics
Genomes (1,963) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 4,963 46,624 13
Proteins 4,956 46,487 13

Functional annotation
General category Regulation
Detailed category Other regulatory function

Function annotation of SCOP domain superfamilies

InterPro annotation
Cross references IPR003718 SSF82784 Protein matches
Abstract Osmotically inducible protein C (OsmC)) is a stress -induced protein found in Escherichia coli. The transcription of the osmC gene of Escherichia coli is regulated as a function of the phase of growth and is induced during the decelerating phase, before entry into stationary phase. The transcription is initiated by two overlapping promoters, osmCp1 and osmCp2 [PubMed8820643].

An organic hydroperoxide detoxification protein (OHR) from Xanthomonas campestris pv. phaseoli is highly induced by organic hydroperoxides, weakly induced by H2O2, and not induced at all by a superoxide generator. Ohr may be a new type of organic hydroperoxide detoxification protein [PubMed9573147].

InterPro database

PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Alignments of sequences to 16 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.

Browse and view proteins in genomes which have different domain combinations including a OsmC-like domain.

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.

Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 16 hidden Markov models representing the OsmC-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Internal database links ]