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Enzyme Commission (EC): Acting on ATP; involved in cellular and subcellular movement  
(show info)
Biomedical Ontology
Like Gene Ontology (GO), biomedical ontology such as phenotype ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Biomedical ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI’s thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology Based on YP which is the major contributor to the ‘Ascomycete phenotype ontology’, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- UniProtKB KeyWords (KW) Ontology Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- CTD Diseases (CD) Ontology CD is MEDIC disease vocabulary that is modified by CTD from the "Diseases" [C] branch of Medical Subject Headings (MeSH), combined with genetic disorders from the Online Mendelian Inheritance in OMIM database.
- CTD Chemicals (CC) Ontology CC is chemical vocabulary that is adapted by CTD from the "Chemicals and Drugs" category and Supplementary Concept Records of Medical Subject Headings (MeSH, a hierarchical vocabulary used to index articles for MEDLINE/PubMed).
Jump to [ Top · Hierarchy · Annotations ]
Root: EC Hierarchy (from IntEnz release 70)
Jump to [ Top · Hierarchy ]
Supra-domain (Single)( show details)
Highlighted in gray are those with FDR>0.001
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Duplex) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
52540,49899 52540 - P-loop containing nucleoside triphosphate hydrolases 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
100920,100934 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
116846,52540 116846 - MIT domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53300,100939 53300 - vWA-like 100939 - SPOC domain-like | 0 | DIRECT |
100939,101420 100939 - SPOC domain-like 101420 - C-terminal domain of Ku80 | 0 | DIRECT |
55608,56712 55608 - Homing endonucleases 56712 - Prokaryotic type I DNA topoisomerase | 0 | DIRECT |
143076,101816 143076 - Coronavirus NSP8-like 101816 - Replicase NSP9 | 0 | DIRECT |
158702,52540 158702 - Sec63 N-terminal domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,-8 52540 - P-loop containing nucleoside triphosphate hydrolases -8 - ECOD | 0 | DIRECT |
52980,47781 52980 - Restriction endonuclease-like 47781 - RuvA domain 2-like | 0 | DIRECT |
52540,47819 52540 - P-loop containing nucleoside triphosphate hydrolases 47819 - HRDC-like | 0 | DIRECT |
100939,68906 100939 - SPOC domain-like 68906 - SAP domain | 0 | DIRECT |
53067,100920 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
53335,56672 53335 - S-adenosyl-L-methionine-dependent methyltransferases 56672 - DNA/RNA polymerases | 0 | DIRECT |
52540,142877 52540 - P-loop containing nucleoside triphosphate hydrolases 142877 - EndoU-like | 0 | DIRECT |
53335,142877 53335 - S-adenosyl-L-methionine-dependent methyltransferases 142877 - EndoU-like | 0 | DIRECT |
54160,54160 54160 - Chromo domain-like 54160 - Chromo domain-like | 0 | DIRECT |
56731,52540 56731 - DNA primase core 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,56712 52540 - P-loop containing nucleoside triphosphate hydrolases 56712 - Prokaryotic type I DNA topoisomerase | 0 | DIRECT |
46785,158702 46785 - "Winged helix" DNA-binding domain 158702 - Sec63 N-terminal domain-like | 0 | DIRECT |
56983,81296 56983 - Viral glycoprotein, central and dimerisation domains 81296 - E set domains | 0 | DIRECT |
52540,54928 52540 - P-loop containing nucleoside triphosphate hydrolases 54928 - RNA-binding domain, RBD | 0 | DIRECT |
53335,52949 53335 - S-adenosyl-L-methionine-dependent methyltransferases 52949 - Macro domain-like | 0 | DIRECT |
54585,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
160481,160481 160481 - BRK domain-like 160481 - BRK domain-like | 0 | DIRECT |
52540,-9 52540 - P-loop containing nucleoside triphosphate hydrolases -9 - PDB | 0 | DIRECT |
52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
46785,47819 46785 - "Winged helix" DNA-binding domain 47819 - HRDC-like | 0 | DIRECT |
47781,46929 47781 - RuvA domain 2-like 46929 - DNA helicase RuvA subunit, C-terminal domain | 0 | DIRECT |
-9,52540 -9 - PDB 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
55464,52540 55464 - Origin of replication-binding domain, RBD-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
101816,144246 101816 - Replicase NSP9 144246 - Coronavirus NSP10-like | 0 | DIRECT |
140367,143076 140367 - Coronavirus NSP7-like 143076 - Coronavirus NSP8-like | 0 | DIRECT |
56672,52540 56672 - DNA/RNA polymerases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
49899,52540 49899 - Concanavalin A-like lectins/glucanases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50916,46785 50916 - Rap30/74 interaction domains 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
48024,52540 48024 - N-terminal domain of DnaB helicase 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,46785 52540 - P-loop containing nucleoside triphosphate hydrolases 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
52540,57756 52540 - P-loop containing nucleoside triphosphate hydrolases 57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
50692,54585 50692 - ADC-like 54585 - Cdc48 domain 2-like | 0 | DIRECT |
54160,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50249,47781 50249 - Nucleic acid-binding proteins 47781 - RuvA domain 2-like | 0 | DIRECT |
52540,48403 52540 - P-loop containing nucleoside triphosphate hydrolases 48403 - Ankyrin repeat | 0 | DIRECT |
158702,81296 158702 - Sec63 N-terminal domain-like 81296 - E set domains | 0 | DIRECT |
50249,52540 50249 - Nucleic acid-binding proteins 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,51294 52540 - P-loop containing nucleoside triphosphate hydrolases 51294 - Hedgehog/intein (Hint) domain | 1.78e-16 | DIRECT |
52540,56672 52540 - P-loop containing nucleoside triphosphate hydrolases 56672 - DNA/RNA polymerases | 0.0000000000003263 | DIRECT |
51197,52540 51197 - Clavaminate synthase-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.000000000000555 | DIRECT |
51294,55608 51294 - Hedgehog/intein (Hint) domain 55608 - Homing endonucleases | 0.0000000001732 | DIRECT |
56712,51294 56712 - Prokaryotic type I DNA topoisomerase 51294 - Hedgehog/intein (Hint) domain | 0.0000002745 | DIRECT |
-8,52540 -8 - ECOD 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.0000002745 | DIRECT |
159936,52949 159936 - NSP3A-like 52949 - Macro domain-like | 0.0000003089 | DIRECT |
159936,53335 159936 - NSP3A-like 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0.000003864 | DIRECT |
55608,52540 55608 - Homing endonucleases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.00001707 | DIRECT |
50494,52540 50494 - Trypsin-like serine proteases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.00002862 | DIRECT |
48403,52540 48403 - Ankyrin repeat 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.48 | INHERITED FROM: RNA helicase |
57756,57756 57756 - Retrovirus zinc finger-like domains 57756 - Retrovirus zinc finger-like domains | 0.9854 | INHERITED FROM: RNA helicase |
56672,88633 56672 - DNA/RNA polymerases 88633 - Positive stranded ssRNA viruses | 1 | INHERITED FROM: RNA helicase |
53067,53067 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain | 1 | INHERITED FROM: Non-chaperonin molecular chaperone ATPase |
50494,56672 50494 - Trypsin-like serine proteases 56672 - DNA/RNA polymerases | 1 | INHERITED FROM: RNA helicase |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
52540,49899 52540 - P-loop containing nucleoside triphosphate hydrolases 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
100920,100934 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
116846,52540 116846 - MIT domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53300,100939 53300 - vWA-like 100939 - SPOC domain-like | 0 | Direct |
100939,101420 100939 - SPOC domain-like 101420 - C-terminal domain of Ku80 | 0 | Direct |
55608,56712 55608 - Homing endonucleases 56712 - Prokaryotic type I DNA topoisomerase | 0 | Direct |
143076,101816 143076 - Coronavirus NSP8-like 101816 - Replicase NSP9 | 0 | Direct |
158702,52540 158702 - Sec63 N-terminal domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,-8 52540 - P-loop containing nucleoside triphosphate hydrolases -8 - ECOD | 0 | Direct |
52980,47781 52980 - Restriction endonuclease-like 47781 - RuvA domain 2-like | 0 | Direct |
52540,47819 52540 - P-loop containing nucleoside triphosphate hydrolases 47819 - HRDC-like | 0 | Direct |
100939,68906 100939 - SPOC domain-like 68906 - SAP domain | 0 | Direct |
53067,100920 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
53335,56672 53335 - S-adenosyl-L-methionine-dependent methyltransferases 56672 - DNA/RNA polymerases | 0 | Direct |
52540,142877 52540 - P-loop containing nucleoside triphosphate hydrolases 142877 - EndoU-like | 0 | Direct |
53335,142877 53335 - S-adenosyl-L-methionine-dependent methyltransferases 142877 - EndoU-like | 0 | Direct |
54160,54160 54160 - Chromo domain-like 54160 - Chromo domain-like | 0 | Direct |
56731,52540 56731 - DNA primase core 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,56712 52540 - P-loop containing nucleoside triphosphate hydrolases 56712 - Prokaryotic type I DNA topoisomerase | 0 | Direct |
46785,158702 46785 - "Winged helix" DNA-binding domain 158702 - Sec63 N-terminal domain-like | 0 | Direct |
56983,81296 56983 - Viral glycoprotein, central and dimerisation domains 81296 - E set domains | 0 | Direct |
52540,54928 52540 - P-loop containing nucleoside triphosphate hydrolases 54928 - RNA-binding domain, RBD | 0 | Direct |
53335,52949 53335 - S-adenosyl-L-methionine-dependent methyltransferases 52949 - Macro domain-like | 0 | Direct |
54585,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
160481,160481 160481 - BRK domain-like 160481 - BRK domain-like | 0 | Direct |
52540,-9 52540 - P-loop containing nucleoside triphosphate hydrolases -9 - PDB | 0 | Direct |
52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
46785,47819 46785 - "Winged helix" DNA-binding domain 47819 - HRDC-like | 0 | Direct |
47781,46929 47781 - RuvA domain 2-like 46929 - DNA helicase RuvA subunit, C-terminal domain | 0 | Direct |
-9,52540 -9 - PDB 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
55464,52540 55464 - Origin of replication-binding domain, RBD-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
101816,144246 101816 - Replicase NSP9 144246 - Coronavirus NSP10-like | 0 | Direct |
140367,143076 140367 - Coronavirus NSP7-like 143076 - Coronavirus NSP8-like | 0 | Direct |
56672,52540 56672 - DNA/RNA polymerases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
49899,52540 49899 - Concanavalin A-like lectins/glucanases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50916,46785 50916 - Rap30/74 interaction domains 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
48024,52540 48024 - N-terminal domain of DnaB helicase 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,46785 52540 - P-loop containing nucleoside triphosphate hydrolases 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
52540,57756 52540 - P-loop containing nucleoside triphosphate hydrolases 57756 - Retrovirus zinc finger-like domains | 0 | Direct |
50692,54585 50692 - ADC-like 54585 - Cdc48 domain 2-like | 0 | Direct |
54160,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50249,47781 50249 - Nucleic acid-binding proteins 47781 - RuvA domain 2-like | 0 | Direct |
52540,48403 52540 - P-loop containing nucleoside triphosphate hydrolases 48403 - Ankyrin repeat | 0 | Direct |
158702,81296 158702 - Sec63 N-terminal domain-like 81296 - E set domains | 0 | Direct |
50249,52540 50249 - Nucleic acid-binding proteins 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,51294 52540 - P-loop containing nucleoside triphosphate hydrolases 51294 - Hedgehog/intein (Hint) domain | 1.78e-16 | Direct |
52540,56672 52540 - P-loop containing nucleoside triphosphate hydrolases 56672 - DNA/RNA polymerases | 0.0000000000003263 | Direct |
51197,52540 51197 - Clavaminate synthase-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.000000000000555 | Direct |
51294,55608 51294 - Hedgehog/intein (Hint) domain 55608 - Homing endonucleases | 0.0000000001732 | Direct |
56712,51294 56712 - Prokaryotic type I DNA topoisomerase 51294 - Hedgehog/intein (Hint) domain | 0.0000002745 | Direct |
-8,52540 -8 - ECOD 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.0000002745 | Direct |
159936,52949 159936 - NSP3A-like 52949 - Macro domain-like | 0.0000003089 | Direct |
159936,53335 159936 - NSP3A-like 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0.000003864 | Direct |
55608,52540 55608 - Homing endonucleases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.00001707 | Direct |
50494,52540 50494 - Trypsin-like serine proteases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.00002862 | Direct |
48403,52540 48403 - Ankyrin repeat 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.48 | Inherited |
57756,57756 57756 - Retrovirus zinc finger-like domains 57756 - Retrovirus zinc finger-like domains | 0.9854 | Inherited |
56672,88633 56672 - DNA/RNA polymerases 88633 - Positive stranded ssRNA viruses | 1 | Inherited |
53067,53067 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain | 1 | Inherited |
50494,56672 50494 - Trypsin-like serine proteases 56672 - DNA/RNA polymerases | 1 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Triple) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50249,47781,46929 50249 - Nucleic acid-binding proteins 47781 - RuvA domain 2-like 46929 - DNA helicase RuvA subunit, C-terminal domain | 0 | DIRECT |
158702,52540,52540 158702 - Sec63 N-terminal domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54160,54160,52540 54160 - Chromo domain-like 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53300,100939,101420 53300 - vWA-like 100939 - SPOC domain-like 101420 - C-terminal domain of Ku80 | 0 | DIRECT |
52540,52540,142877 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 142877 - EndoU-like | 0 | DIRECT |
46785,158702,81296 46785 - "Winged helix" DNA-binding domain 158702 - Sec63 N-terminal domain-like 81296 - E set domains | 0 | DIRECT |
51197,52540,56672 51197 - Clavaminate synthase-like 52540 - P-loop containing nucleoside triphosphate hydrolases 56672 - DNA/RNA polymerases | 0 | DIRECT |
50692,54585,52540 50692 - ADC-like 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53067,53067,100920 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
52540,46785,47819 52540 - P-loop containing nucleoside triphosphate hydrolases 46785 - "Winged helix" DNA-binding domain 47819 - HRDC-like | 0 | DIRECT |
52540,56712,51294 52540 - P-loop containing nucleoside triphosphate hydrolases 56712 - Prokaryotic type I DNA topoisomerase 51294 - Hedgehog/intein (Hint) domain | 0 | DIRECT |
52540,52540,56712 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 56712 - Prokaryotic type I DNA topoisomerase | 0 | DIRECT |
52540,52540,56672 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 56672 - DNA/RNA polymerases | 0 | DIRECT |
48024,52540,51294 48024 - N-terminal domain of DnaB helicase 52540 - P-loop containing nucleoside triphosphate hydrolases 51294 - Hedgehog/intein (Hint) domain | 0 | DIRECT |
52540,52540,46785 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
52540,46785,158702 52540 - P-loop containing nucleoside triphosphate hydrolases 46785 - "Winged helix" DNA-binding domain 158702 - Sec63 N-terminal domain-like | 0 | DIRECT |
52540,52540,47819 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 47819 - HRDC-like | 0 | DIRECT |
56672,52540,52540 56672 - DNA/RNA polymerases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
140367,143076,101816 140367 - Coronavirus NSP7-like 143076 - Coronavirus NSP8-like 101816 - Replicase NSP9 | 0 | DIRECT |
54160,52540,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50494,52540,52540 50494 - Trypsin-like serine proteases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50249,52540,52540 50249 - Nucleic acid-binding proteins 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
143076,101816,144246 143076 - Coronavirus NSP8-like 101816 - Replicase NSP9 144246 - Coronavirus NSP10-like | 0 | DIRECT |
46785,158702,52540 46785 - "Winged helix" DNA-binding domain 158702 - Sec63 N-terminal domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54585,52540,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53300,100939,68906 53300 - vWA-like 100939 - SPOC domain-like 68906 - SAP domain | 0 | DIRECT |
52540,49899,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 49899 - Concanavalin A-like lectins/glucanases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51197,52540,52540 51197 - Clavaminate synthase-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,48403,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 48403 - Ankyrin repeat 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53067,100920,100934 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
52540,51294,55608 52540 - P-loop containing nucleoside triphosphate hydrolases 51294 - Hedgehog/intein (Hint) domain 55608 - Homing endonucleases | 0.0000000008533 | DIRECT |
52540,52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.0000002745 | DIRECT |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50249,47781,46929 50249 - Nucleic acid-binding proteins 47781 - RuvA domain 2-like 46929 - DNA helicase RuvA subunit, C-terminal domain | 0 | Direct |
158702,52540,52540 158702 - Sec63 N-terminal domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54160,54160,52540 54160 - Chromo domain-like 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53300,100939,101420 53300 - vWA-like 100939 - SPOC domain-like 101420 - C-terminal domain of Ku80 | 0 | Direct |
52540,52540,142877 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 142877 - EndoU-like | 0 | Direct |
46785,158702,81296 46785 - "Winged helix" DNA-binding domain 158702 - Sec63 N-terminal domain-like 81296 - E set domains | 0 | Direct |
51197,52540,56672 51197 - Clavaminate synthase-like 52540 - P-loop containing nucleoside triphosphate hydrolases 56672 - DNA/RNA polymerases | 0 | Direct |
50692,54585,52540 50692 - ADC-like 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53067,53067,100920 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
52540,46785,47819 52540 - P-loop containing nucleoside triphosphate hydrolases 46785 - "Winged helix" DNA-binding domain 47819 - HRDC-like | 0 | Direct |
52540,56712,51294 52540 - P-loop containing nucleoside triphosphate hydrolases 56712 - Prokaryotic type I DNA topoisomerase 51294 - Hedgehog/intein (Hint) domain | 0 | Direct |
52540,52540,56712 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 56712 - Prokaryotic type I DNA topoisomerase | 0 | Direct |
52540,52540,56672 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 56672 - DNA/RNA polymerases | 0 | Direct |
48024,52540,51294 48024 - N-terminal domain of DnaB helicase 52540 - P-loop containing nucleoside triphosphate hydrolases 51294 - Hedgehog/intein (Hint) domain | 0 | Direct |
52540,52540,46785 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
52540,46785,158702 52540 - P-loop containing nucleoside triphosphate hydrolases 46785 - "Winged helix" DNA-binding domain 158702 - Sec63 N-terminal domain-like | 0 | Direct |
52540,52540,47819 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 47819 - HRDC-like | 0 | Direct |
56672,52540,52540 56672 - DNA/RNA polymerases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
140367,143076,101816 140367 - Coronavirus NSP7-like 143076 - Coronavirus NSP8-like 101816 - Replicase NSP9 | 0 | Direct |
54160,52540,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50494,52540,52540 50494 - Trypsin-like serine proteases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50249,52540,52540 50249 - Nucleic acid-binding proteins 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
143076,101816,144246 143076 - Coronavirus NSP8-like 101816 - Replicase NSP9 144246 - Coronavirus NSP10-like | 0 | Direct |
46785,158702,52540 46785 - "Winged helix" DNA-binding domain 158702 - Sec63 N-terminal domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54585,52540,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53300,100939,68906 53300 - vWA-like 100939 - SPOC domain-like 68906 - SAP domain | 0 | Direct |
52540,49899,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 49899 - Concanavalin A-like lectins/glucanases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51197,52540,52540 51197 - Clavaminate synthase-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,48403,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 48403 - Ankyrin repeat 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53067,100920,100934 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
52540,51294,55608 52540 - P-loop containing nucleoside triphosphate hydrolases 51294 - Hedgehog/intein (Hint) domain 55608 - Homing endonucleases | 0.0000000008533 | Direct |
52540,52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.0000002745 | Direct |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Plot distribution on species Tree Of Life (sTOL) for Superfamily and/or Family domains annotated by this EC term
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Plot tree as:
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Download Newick format tree:
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( show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domain
architecture data for all genomes in SUPERFAMILY. The PAUP
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
Plot distribution on species Tree Of Life (sTOL) for single supra-domains annotated by this EC term
 |
Plot tree as:
| |
Download Newick format tree:
| |
Browsing in TREE OF LIFE:
|
( show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
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