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Enzyme Commission (EC): Carbon-oxygen lyases 
(show info)
Biomedical Ontology
Like Gene Ontology (GO), biomedical ontology such as phenotype ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Biomedical ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI’s thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology Based on YP which is the major contributor to the ‘Ascomycete phenotype ontology’, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- UniProtKB KeyWords (KW) Ontology Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- CTD Diseases (CD) Ontology CD is MEDIC disease vocabulary that is modified by CTD from the "Diseases" [C] branch of Medical Subject Headings (MeSH), combined with genetic disorders from the Online Mendelian Inheritance in OMIM database.
- CTD Chemicals (CC) Ontology CC is chemical vocabulary that is adapted by CTD from the "Chemicals and Drugs" category and Supplementary Concept Records of Medical Subject Headings (MeSH, a hierarchical vocabulary used to index articles for MEDLINE/PubMed).
Jump to [ Top · Hierarchy · Annotations ]
Root: EC Hierarchy (from IntEnz release 70)
Jump to [ Top · Hierarchy ]
Superfamily( show details)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| PCD-like | 0 | DIRECT |
| Xylose isomerase-like | 0 | DIRECT |
| Urocanase | 0 | DIRECT |
| Methylglyoxal synthase-like | 0 | DIRECT |
| Bacterial muramidases | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| Lysozyme-like | 0 | DIRECT |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
| Enolase N-terminal domain-like | 0 | DIRECT |
| Chondroitin AC/alginate lyase | 0 | DIRECT |
| Aconitase B, N-terminal domain | 0 | DIRECT |
| Chorismate synthase, AroC | 0 | DIRECT |
| ClpP/crotonase | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| Indigoidine synthase A-like | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| beta-carbonic anhydrase, cab | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
| LeuD/IlvD-like | 0 | DIRECT |
| FumA C-terminal domain-like | 0 | DIRECT |
| lambda repressor-like DNA-binding domains | 0 | DIRECT |
| Hyaluronate lyase-like, C-terminal domain | 0 | DIRECT |
| Type II 3-dehydroquinate dehydratase | 0 | DIRECT |
| Ribosomal protein S3 C-terminal domain | 0 | DIRECT |
| AraD/HMP-PK domain-like | 0 | DIRECT |
| S13-like H2TH domain | 0 | DIRECT |
| Enolase C-terminal domain-like | 0 | DIRECT |
| HemD-like | 0 | DIRECT |
| N-terminal domain of MutM-like DNA repair proteins | 0 | DIRECT |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
| Pectin lyase-like | 0 | DIRECT |
| IlvD/EDD N-terminal domain-like | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| Ribosomal protein S5 domain 2-like | 0 | DIRECT |
| DNA-glycosylase | 0 | DIRECT |
| AttH-like | 0 | DIRECT |
| Prokaryotic type KH domain (KH-domain type II) | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| Cyanase C-terminal domain | 0 | DIRECT |
| Dehydroquinate synthase-like | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| YjeF N-terminal domain-like | 0.0000000000001663 | DIRECT |
| Nitrile hydratase alpha chain | 0.000000000004869 | DIRECT |
| Ribokinase-like | 0.000000000005454 | DIRECT |
| Starch-binding domain-like | 0.00000000008802 | DIRECT |
| Electron transport accessory proteins | 0.000000002626 | DIRECT |
| Chorismate mutase II | 0.000000006424 | DIRECT |
| TATA-box binding protein-like | 0.00000005336 | DIRECT |
| Galactose mutarotase-like | 0.0000003408 | DIRECT |
| HSP20-like chaperones | 0.00008667 | DIRECT |
| Barwin-like endoglucanases | 0.0001891 | DIRECT |
| DNase I-like | 0.0007123 | DIRECT |
| SCP-like | 0.001621 | INHERITED FROM: hydratase || Hydro-lyases || Enoyl-CoA hydratase 2 |
| 2-methylcitrate dehydratase PrpD | 0.007637 | INHERITED FROM: Hydro-lyases || 2-methylcitrate dehydratase || Aconitate hydratase |
| Cytochrome P450 | 0.03005 | INHERITED FROM: Hydroperoxide dehydratase || Colneleate synthase || Hydro-lyases || Hydroperoxy icosatetraenoate dehydratase |
| CBS-domain pair | 0.03689 | INHERITED FROM: Cystathionine beta-synthase |
| Ran binding protein zinc finger-like | 0.0616 | INHERITED FROM: DNA-(apurinic or apyrimidinic site) lyase || Other carbon-oxygen lyases |
| FAH | 0.09093 | INHERITED FROM: Hydro-lyases || 2-oxopent-4-enoate hydratase |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0.1387 | INHERITED FROM: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase |
| FabD/lysophospholipase-like | 0.1397 | INHERITED FROM: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase |
| Carbon-nitrogen hydrolase | 0.1883 | INHERITED FROM: 3-cyanoalanine hydratase || Cyanide hydratase |
| ACP-like | 0.2215 | INHERITED FROM: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase |
| NTF2-like | 0.2215 | INHERITED FROM: Scytalone dehydratase |
| HAD-like | 0.2872 | INHERITED FROM: Imidazoleglycerol-phosphate dehydratase || Methylthioribulose 1-phosphate dehydratase |
| Bet v1-like | 0.302 | INHERITED FROM: (S)-norcoclaurine synthase |
| ACT-like | 0.3148 | INHERITED FROM: Prephenate dehydratase || Arogenate dehydratase |
| Lipoxigenase | 0.3599 | INHERITED FROM: Hydroperoxy icosatetraenoate dehydratase |
| Diaminopimelate epimerase-like | 0.3705 | INHERITED FROM: Trans-L-3-hydroxyproline dehydratase |
| EPT/RTPC-like | 0.376 | INHERITED FROM: Acting on phosphates || 3-dehydroquinate synthase || 3-dehydroquinate dehydratase |
| Galactose-binding domain-like | 0.4158 | INHERITED FROM: Acting on polysaccharides || Chondroitin-sulfate-ABC exolyase || Rhamnogalacturonan endolyase |
| UBA-like | 0.4281 | INHERITED FROM: N-acetylmuramic acid 6-phosphate etherase |
| SMAD/FHA domain | 0.4811 | INHERITED FROM: DNA-(apurinic or apyrimidinic site) lyase || Other carbon-oxygen lyases |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0.7352 | INHERITED FROM: Hydroperoxy icosatetraenoate dehydratase |
| RmlC-like cupins | 0.804 | INHERITED FROM: Ectoine synthase || Hydro-lyases |
| Aminoacid dehydrogenase-like, N-terminal domain | 0.9294 | INHERITED FROM: Acting on phosphates || 3-dehydroquinate synthase || 3-dehydroquinate dehydratase |
| Triosephosphate isomerase (TIM) | 0.9932 | INHERITED FROM: Acting on phosphates || Methylglyoxal synthase |
| L-aspartase-like | 1 | INHERITED FROM: Fumarate hydratase || Hydro-lyases |
| alpha/beta-Hydrolases | 1 | INHERITED FROM: Tuliposide A-converting enzyme || 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase || Other carbon-oxygen lyases |
| FAD/NAD(P)-binding domain | 1 | INHERITED FROM: Oleate hydratase |
| PLP-dependent transferases | 1 | INHERITED FROM: Ethanolamine-phosphate phospho-lyase |
| Aldolase | 1 | INHERITED FROM: 5-dehydro-4-deoxyglucarate dehydratase || 3-dehydroquinate synthase || Porphobilinogen synthase || 3-dehydroquinate dehydratase || Hydro-lyases || (5-formylfuran-3-yl)methyl phosphate synthase |
| Tetrahydrobiopterin biosynthesis enzymes-like | 1 | INHERITED FROM: 6-pyruvoyltetrahydropterin synthase |
| Class I glutamine amidotransferase-like | 1 | INHERITED FROM: D-lactate dehydratase |
| P-loop containing nucleoside triphosphate hydrolases | 1 | INHERITED FROM: 3-dehydroquinate synthase |
| Ribulose-phoshate binding barrel | 1 | INHERITED FROM: Tryptophan synthase || 5,6,7,8-tetrahydromethanopterin hydro-lyase || Hydro-lyases || (5-formylfuran-3-yl)methyl phosphate synthase |
| NAD(P)-binding Rossmann-fold domains | 1 | INHERITED FROM: Enoyl-CoA hydratase || hydratase || dTDP-glucose 4,6-dehydratase || UDP-N-acetylglucosamine 4,6-dehydratase (inverting) || UDP-glucose 4,6-dehydratase || GDP-mannose 4,6-dehydratase || 3-dehydroquinate synthase || 3-dehydroquinate dehydratase || Enoyl-CoA hydratase 2 |
LINKTO: Domain2BO Download and Domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Family( show details)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| HCDH C-domain-like | 0 | DIRECT |
| Rhamnogalacturonase B, RhgB, middle domain | 0 | DIRECT |
| D-glucarate dehydratase-like | 0 | DIRECT |
| Terpenoid cyclase N-terminal domain | 0 | DIRECT |
| Cyanase C-terminal domain | 0 | DIRECT |
| UxuA-like | 0 | DIRECT |
| Ribosomal protein S3 C-terminal domain | 0 | DIRECT |
| Bacterial muramidases | 0 | DIRECT |
| IlvD/EDD C-terminal domain-like | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| Scytalone dehydratase | 0 | DIRECT |
| Bacterial muramidase, catalytic domain | 0 | DIRECT |
| FumA C-terminal domain-like | 0 | DIRECT |
| Terpenoid cyclase C-terminal domain | 0 | DIRECT |
| 6-phosphogluconate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| beta-Hydroxydecanol thiol ester dehydrase | 0 | DIRECT |
| FabZ-like | 0 | DIRECT |
| C-terminal, Zn-finger domain of MutM-like DNA repair proteins | 0 | DIRECT |
| lvD/EDD N-terminal domain-like | 0 | DIRECT |
| Cyanase N-terminal domain | 0 | DIRECT |
| Hyaluronate lyase-like, central domain | 0 | DIRECT |
| Nitrile hydratase beta chain | 0 | DIRECT |
| AraD-like aldolase/epimerase | 0 | DIRECT |
| Aristolochene/pentalenene synthase | 0 | DIRECT |
| Dimeric chorismate mutase | 0 | DIRECT |
| YjeF C-terminal domain-like | 0 | DIRECT |
| Hypothetical protein VC1974 | 0 | DIRECT |
| Dehydroquinate synthase, DHQS | 0 | DIRECT |
| LeuD-like | 0 | DIRECT |
| Rhamnogalacturonase B, RhgB, N-terminal domain | 0 | DIRECT |
| MaoC-like | 0 | DIRECT |
| AttH-like | 0 | DIRECT |
| mono-SIS domain | 0 | DIRECT |
| 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) | 0 | DIRECT |
| Hyaluronate lyase-like catalytic, N-terminal domain | 0 | DIRECT |
| HemD-like | 0 | DIRECT |
| Alginate lyase A1-III | 0 | DIRECT |
| MLTA-like | 0 | DIRECT |
| Rhamnogalacturonase B, RhgB, C-terminal domain | 0 | DIRECT |
| Formaldehyde-activating enzyme, FAE | 0 | DIRECT |
| Hyaluronate lyase-like, C-terminal domain | 0 | DIRECT |
| N-terminal domain of MutM-like DNA repair proteins | 0 | DIRECT |
| Chorismate synthase, AroC | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| Type II 3-dehydroquinate dehydratase | 0 | DIRECT |
| Trichodiene synthase | 0 | DIRECT |
| Crotonase-like | 0 | DIRECT |
| Enolase N-terminal domain-like | 0 | DIRECT |
| Methylglyoxal synthase, MgsA | 0 | DIRECT |
| Prokaryotic type KH domain (KH-domain type II) | 0 | DIRECT |
| Histidinol phosphatase-like | 0 | DIRECT |
| Pectate lyase-like | 0 | DIRECT |
| PCD-like | 0 | DIRECT |
| Endonuclease III | 0 | DIRECT |
| Enolase | 0 | DIRECT |
| Urocanase | 0 | DIRECT |
| Indigoidine synthase A-like | 0 | DIRECT |
| AgoG-like | 0 | DIRECT |
| beta-carbonic anhydrase, cab | 0 | DIRECT |
| Middle domain of MutM-like DNA repair proteins | 0 | DIRECT |
| Pectate transeliminase | 0 | DIRECT |
| Pectin lyase | 0 | DIRECT |
| Chondroitin ABC lyase I, N-terminal domain | 0 | DIRECT |
| Aconitase B, N-terminal domain | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| Imidazole glycerol phosphate dehydratase | 0 | DIRECT |
| Phosphate binding protein-like | 5.532e-16 | DIRECT |
| Shikimate kinase (AroK) | 0.000000000000001463 | DIRECT |
| DNase I-like | 0.00000000000001797 | DIRECT |
| Proline racemase | 0.0000000000001325 | DIRECT |
| YjeF N-terminal domain-like | 0.0000000000005668 | DIRECT |
| Phenylalanine metabolism regulatory domain | 0.000000000002454 | DIRECT |
| Nitrile hydratase alpha chain | 0.000000000006128 | DIRECT |
| Shikimate dehydrogenase-like | 0.00000000002744 | DIRECT |
| Tryptophan biosynthesis enzymes | 0.00000001882 | DIRECT |
| Co-chaperone p23-like | 0.00000006216 | DIRECT |
| DNA repair glycosylase, N-terminal domain | 0.00000006216 | DIRECT |
| DNA repair glycosylase, 2 C-terminal domains | 0.0000002264 | DIRECT |
| Acyl-carrier protein (ACP) | 0.0000002309 | DIRECT |
| DJ-1/PfpI | 0.000007246 | DIRECT |
| Thioesterase domain of polypeptide, polyketide and fatty acid synthases | 0.0001042 | DIRECT |
| FabD-like | 0.000178 | DIRECT |
| Carboxylesterase | 0.0008217 | DIRECT |
| Sterol carrier protein, SCP | 0.001689 | INHERITED FROM: hydratase || Hydro-lyases || Enoyl-CoA hydratase 2 |
| 2-methylcitrate dehydratase PrpD | 0.006482 | INHERITED FROM: Hydro-lyases || 2-methylcitrate dehydratase || Aconitate hydratase |
| Animal lipoxigenases | 0.008202 | INHERITED FROM: Hydroperoxy icosatetraenoate dehydratase |
| Terpene synthases | 0.02332 | INHERITED FROM: Squalene--hopanol cyclase |
| CBS-domain pair | 0.03615 | INHERITED FROM: Cystathionine beta-synthase |
| Ran binding protein zinc finger-like | 0.06445 | INHERITED FROM: DNA-(apurinic or apyrimidinic site) lyase || Other carbon-oxygen lyases |
| Cytochrome P450 | 0.07241 | INHERITED FROM: Hydroperoxide dehydratase || Colneleate synthase || Hydro-lyases || Hydroperoxy icosatetraenoate dehydratase |
| FAH | 0.1044 | INHERITED FROM: Hydro-lyases || 2-oxopent-4-enoate hydratase |
| Tyrosine-dependent oxidoreductases | 0.1505 | INHERITED FROM: hydratase || dTDP-glucose 4,6-dehydratase || UDP-N-acetylglucosamine 4,6-dehydratase (inverting) || UDP-glucose 4,6-dehydratase || GDP-mannose 4,6-dehydratase || Hydro-lyases || Enoyl-CoA hydratase 2 |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0.1895 | INHERITED FROM: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase |
| Enolase-phosphatase E1 | 0.2741 | INHERITED FROM: Methylthioribulose 1-phosphate dehydratase |
| Enolpyruvate transferase, EPT | 0.2803 | INHERITED FROM: Acting on phosphates || 3-dehydroquinate synthase || 3-dehydroquinate dehydratase |
| Lipoxigenase N-terminal domain | 0.4143 | INHERITED FROM: Hydroperoxy icosatetraenoate dehydratase |
| FHA domain | 0.4542 | INHERITED FROM: DNA-(apurinic or apyrimidinic site) lyase || Other carbon-oxygen lyases |
| Triosephosphate isomerase (TIM) | 0.9886 | INHERITED FROM: Acting on phosphates || Methylglyoxal synthase |
| 6-pyruvoyl tetrahydropterin synthase | 0.9924 | INHERITED FROM: Acting on phosphates || 6-pyruvoyltetrahydropterin synthase |
| Thiolase-related | 1 | INHERITED FROM: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase |
| Class I aldolase | 1 | INHERITED FROM: 5-dehydro-4-deoxyglucarate dehydratase || 3-dehydroquinate synthase || 3-dehydroquinate dehydratase || Hydro-lyases |
| Aminoacid dehydrogenase-like, C-terminal domain | 1 | INHERITED FROM: 3-dehydroquinate synthase || 3-dehydroquinate dehydratase |
| L-aspartase/fumarase | 1 | INHERITED FROM: Fumarate hydratase || Hydro-lyases |
| GABA-aminotransferase-like | 1 | INHERITED FROM: Ethanolamine-phosphate phospho-lyase |
| Decarboxylase | 1 | INHERITED FROM: 5,6,7,8-tetrahydromethanopterin hydro-lyase |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| HCDH C-domain-like | 0 | Direct |
| Rhamnogalacturonase B, RhgB, middle domain | 0 | Direct |
| D-glucarate dehydratase-like | 0 | Direct |
| Terpenoid cyclase N-terminal domain | 0 | Direct |
| Cyanase C-terminal domain | 0 | Direct |
| UxuA-like | 0 | Direct |
| Ribosomal protein S3 C-terminal domain | 0 | Direct |
| Bacterial muramidases | 0 | Direct |
| IlvD/EDD C-terminal domain-like | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| Scytalone dehydratase | 0 | Direct |
| Bacterial muramidase, catalytic domain | 0 | Direct |
| FumA C-terminal domain-like | 0 | Direct |
| Terpenoid cyclase C-terminal domain | 0 | Direct |
| 6-phosphogluconate dehydrogenase-like, N-terminal domain | 0 | Direct |
| beta-Hydroxydecanol thiol ester dehydrase | 0 | Direct |
| FabZ-like | 0 | Direct |
| C-terminal, Zn-finger domain of MutM-like DNA repair proteins | 0 | Direct |
| lvD/EDD N-terminal domain-like | 0 | Direct |
| Cyanase N-terminal domain | 0 | Direct |
| Hyaluronate lyase-like, central domain | 0 | Direct |
| Nitrile hydratase beta chain | 0 | Direct |
| AraD-like aldolase/epimerase | 0 | Direct |
| Aristolochene/pentalenene synthase | 0 | Direct |
| Dimeric chorismate mutase | 0 | Direct |
| YjeF C-terminal domain-like | 0 | Direct |
| Hypothetical protein VC1974 | 0 | Direct |
| Dehydroquinate synthase, DHQS | 0 | Direct |
| LeuD-like | 0 | Direct |
| Rhamnogalacturonase B, RhgB, N-terminal domain | 0 | Direct |
| MaoC-like | 0 | Direct |
| AttH-like | 0 | Direct |
| mono-SIS domain | 0 | Direct |
| 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) | 0 | Direct |
| Hyaluronate lyase-like catalytic, N-terminal domain | 0 | Direct |
| HemD-like | 0 | Direct |
| Alginate lyase A1-III | 0 | Direct |
| MLTA-like | 0 | Direct |
| Rhamnogalacturonase B, RhgB, C-terminal domain | 0 | Direct |
| Formaldehyde-activating enzyme, FAE | 0 | Direct |
| Hyaluronate lyase-like, C-terminal domain | 0 | Direct |
| N-terminal domain of MutM-like DNA repair proteins | 0 | Direct |
| Chorismate synthase, AroC | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| Type II 3-dehydroquinate dehydratase | 0 | Direct |
| Trichodiene synthase | 0 | Direct |
| Crotonase-like | 0 | Direct |
| Enolase N-terminal domain-like | 0 | Direct |
| Methylglyoxal synthase, MgsA | 0 | Direct |
| Prokaryotic type KH domain (KH-domain type II) | 0 | Direct |
| Histidinol phosphatase-like | 0 | Direct |
| Pectate lyase-like | 0 | Direct |
| PCD-like | 0 | Direct |
| Endonuclease III | 0 | Direct |
| Enolase | 0 | Direct |
| Urocanase | 0 | Direct |
| Indigoidine synthase A-like | 0 | Direct |
| AgoG-like | 0 | Direct |
| beta-carbonic anhydrase, cab | 0 | Direct |
| Middle domain of MutM-like DNA repair proteins | 0 | Direct |
| Pectate transeliminase | 0 | Direct |
| Pectin lyase | 0 | Direct |
| Chondroitin ABC lyase I, N-terminal domain | 0 | Direct |
| Aconitase B, N-terminal domain | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| Imidazole glycerol phosphate dehydratase | 0 | Direct |
| Phosphate binding protein-like | 5.532e-16 | Direct |
| Shikimate kinase (AroK) | 0.000000000000001463 | Direct |
| DNase I-like | 0.00000000000001797 | Direct |
| Proline racemase | 0.0000000000001325 | Direct |
| YjeF N-terminal domain-like | 0.0000000000005668 | Direct |
| Phenylalanine metabolism regulatory domain | 0.000000000002454 | Direct |
| Nitrile hydratase alpha chain | 0.000000000006128 | Direct |
| Shikimate dehydrogenase-like | 0.00000000002744 | Direct |
| Tryptophan biosynthesis enzymes | 0.00000001882 | Direct |
| Co-chaperone p23-like | 0.00000006216 | Direct |
| DNA repair glycosylase, N-terminal domain | 0.00000006216 | Direct |
| DNA repair glycosylase, 2 C-terminal domains | 0.0000002264 | Direct |
| Acyl-carrier protein (ACP) | 0.0000002309 | Direct |
| DJ-1/PfpI | 0.000007246 | Direct |
| Thioesterase domain of polypeptide, polyketide and fatty acid synthases | 0.0001042 | Direct |
| FabD-like | 0.000178 | Direct |
| Carboxylesterase | 0.0008217 | Direct |
| Sterol carrier protein, SCP | 0.001689 | Inherited |
| 2-methylcitrate dehydratase PrpD | 0.006482 | Inherited |
| Animal lipoxigenases | 0.008202 | Inherited |
| Terpene synthases | 0.02332 | Inherited |
| CBS-domain pair | 0.03615 | Inherited |
| Ran binding protein zinc finger-like | 0.06445 | Inherited |
| Cytochrome P450 | 0.07241 | Inherited |
| FAH | 0.1044 | Inherited |
| Tyrosine-dependent oxidoreductases | 0.1505 | Inherited |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0.1895 | Inherited |
| Enolase-phosphatase E1 | 0.2741 | Inherited |
| Enolpyruvate transferase, EPT | 0.2803 | Inherited |
| Lipoxigenase N-terminal domain | 0.4143 | Inherited |
| FHA domain | 0.4542 | Inherited |
| Triosephosphate isomerase (TIM) | 0.9886 | Inherited |
| 6-pyruvoyl tetrahydropterin synthase | 0.9924 | Inherited |
| Thiolase-related | 1 | Inherited |
| Class I aldolase | 1 | Inherited |
| Aminoacid dehydrogenase-like, C-terminal domain | 1 | Inherited |
| L-aspartase/fumarase | 1 | Inherited |
| GABA-aminotransferase-like | 1 | Inherited |
| Decarboxylase | 1 | Inherited |
LINKTO: Domain2BO Download and Domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Single)( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| IlvD/EDD N-terminal domain-like | 0 | DIRECT |
| Enolase N-terminal domain-like | 0 | DIRECT |
| Ribosomal protein S5 domain 2-like | 0 | DIRECT |
| DNA-glycosylase | 0 | DIRECT |
| FumA C-terminal domain-like | 0 | DIRECT |
| Urocanase | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| Chondroitin AC/alginate lyase | 0 | DIRECT |
| Cyanase C-terminal domain | 0 | DIRECT |
| Lysozyme-like | 0 | DIRECT |
| ClpP/crotonase | 0 | DIRECT |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| Methylglyoxal synthase-like | 0 | DIRECT |
| lambda repressor-like DNA-binding domains | 0 | DIRECT |
| S13-like H2TH domain | 0 | DIRECT |
| Hyaluronate lyase-like, C-terminal domain | 0 | DIRECT |
| Aconitase B, N-terminal domain | 0 | DIRECT |
| Dehydroquinate synthase-like | 0 | DIRECT |
| Indigoidine synthase A-like | 0 | DIRECT |
| beta-carbonic anhydrase, cab | 0 | DIRECT |
| Prokaryotic type KH domain (KH-domain type II) | 0 | DIRECT |
| Chorismate synthase, AroC | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| AraD/HMP-PK domain-like | 0 | DIRECT |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| Ribosomal protein S3 C-terminal domain | 0 | DIRECT |
| Pectin lyase-like | 0 | DIRECT |
| HemD-like | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| N-terminal domain of MutM-like DNA repair proteins | 0 | DIRECT |
| PCD-like | 0 | DIRECT |
| Type II 3-dehydroquinate dehydratase | 0 | DIRECT |
| Bacterial muramidases | 0 | DIRECT |
| Xylose isomerase-like | 0 | DIRECT |
| Enolase C-terminal domain-like | 0 | DIRECT |
| AttH-like | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
| LeuD/IlvD-like | 0 | DIRECT |
| YjeF N-terminal domain-like | 0.000000000000118 | DIRECT |
| Nitrile hydratase alpha chain | 0.00000000000351 | DIRECT |
| Ribokinase-like | 0.000000000003932 | DIRECT |
| Starch-binding domain-like | 0.00000000006462 | DIRECT |
| Electron transport accessory proteins | 0.000000001965 | DIRECT |
| Chorismate mutase II | 0.000000004837 | DIRECT |
| TATA-box binding protein-like | 0.00000004063 | DIRECT |
| Galactose mutarotase-like | 0.0000002628 | DIRECT |
| HSP20-like chaperones | 0.00006978 | DIRECT |
| Barwin-like endoglucanases | 0.0001534 | DIRECT |
| DNase I-like | 0.0005851 | DIRECT |
| Integrin alpha N-terminal domain | 0.0008454 | DIRECT |
| SCP-like | 0.001344 | INHERITED FROM: Enoyl-CoA hydratase 2 || hydratase || Hydro-lyases |
| 2-methylcitrate dehydratase PrpD | 0.006443 | INHERITED FROM: 2-methylcitrate dehydratase || Aconitate hydratase || Hydro-lyases |
| Cytochrome P450 | 0.0258 | INHERITED FROM: Hydroperoxy icosatetraenoate dehydratase || Hydro-lyases || Colneleate synthase || Hydroperoxide dehydratase |
| CBS-domain pair | 0.03171 | INHERITED FROM: Cystathionine beta-synthase |
| Ran binding protein zinc finger-like | 0.0534 | INHERITED FROM: Other carbon-oxygen lyases || DNA-(apurinic or apyrimidinic site) lyase |
| FAH | 0.0792 | INHERITED FROM: 2-oxopent-4-enoate hydratase || Hydro-lyases |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0.1217 | INHERITED FROM: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase |
| FabD/lysophospholipase-like | 0.1226 | INHERITED FROM: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase |
| Carbon-nitrogen hydrolase | 0.1666 | INHERITED FROM: Cyanide hydratase || 3-cyanoalanine hydratase |
| ACP-like | 0.1968 | INHERITED FROM: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase |
| NTF2-like | 0.1968 | INHERITED FROM: Scytalone dehydratase |
| HAD-like | 0.2589 | INHERITED FROM: Imidazoleglycerol-phosphate dehydratase || Methylthioribulose 1-phosphate dehydratase || Hydro-lyases |
| Bet v1-like | 0.2725 | INHERITED FROM: (S)-norcoclaurine synthase |
| ACT-like | 0.2843 | INHERITED FROM: Prephenate dehydratase || Arogenate dehydratase |
| Lipoxigenase | 0.3256 | INHERITED FROM: Hydroperoxy icosatetraenoate dehydratase |
| Diaminopimelate epimerase-like | 0.3353 | INHERITED FROM: Trans-L-3-hydroxyproline dehydratase |
| EPT/RTPC-like | 0.3404 | INHERITED FROM: Acting on phosphates || 3-dehydroquinate dehydratase || 3-dehydroquinate synthase |
| Galactose-binding domain-like | 0.3773 | INHERITED FROM: Rhamnogalacturonan endolyase || Chondroitin-sulfate-ABC exolyase || Acting on polysaccharides |
| UBA-like | 0.389 | INHERITED FROM: N-acetylmuramic acid 6-phosphate etherase |
| SMAD/FHA domain | 0.4388 | INHERITED FROM: Other carbon-oxygen lyases || DNA-(apurinic or apyrimidinic site) lyase |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0.6761 | INHERITED FROM: Hydroperoxy icosatetraenoate dehydratase |
| RmlC-like cupins | 0.7403 | INHERITED FROM: Ectoine synthase || Hydro-lyases |
| Aminoacid dehydrogenase-like, N-terminal domain | 0.8589 | INHERITED FROM: Acting on phosphates || 3-dehydroquinate dehydratase || 3-dehydroquinate synthase |
| Triosephosphate isomerase (TIM) | 0.92 | INHERITED FROM: Methylglyoxal synthase || Acting on phosphates |
| FAD/NAD(P)-binding domain | 1 | INHERITED FROM: Oleate hydratase |
| PLP-dependent transferases | 1 | INHERITED FROM: Ethanolamine-phosphate phospho-lyase |
| P-loop containing nucleoside triphosphate hydrolases | 1 | INHERITED FROM: 3-dehydroquinate synthase |
| NAD(P)-binding Rossmann-fold domains | 1 | INHERITED FROM: UDP-glucose 4,6-dehydratase || UDP-N-acetylglucosamine 4,6-dehydratase (inverting) || Enoyl-CoA hydratase || GDP-mannose 4,6-dehydratase || dTDP-glucose 4,6-dehydratase || Enoyl-CoA hydratase 2 || hydratase || 3-dehydroquinate dehydratase || 3-dehydroquinate synthase |
| alpha/beta-Hydrolases | 1 | INHERITED FROM: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase || Other carbon-oxygen lyases || Tuliposide A-converting enzyme |
| Tetrahydrobiopterin biosynthesis enzymes-like | 1 | INHERITED FROM: 6-pyruvoyltetrahydropterin synthase |
| Aldolase | 1 | INHERITED FROM: Porphobilinogen synthase || (5-formylfuran-3-yl)methyl phosphate synthase || 5-dehydro-4-deoxyglucarate dehydratase || 3-dehydroquinate dehydratase || Hydro-lyases || 3-dehydroquinate synthase |
| Class I glutamine amidotransferase-like | 1 | INHERITED FROM: D-lactate dehydratase |
| Ribulose-phoshate binding barrel | 1 | INHERITED FROM: (5-formylfuran-3-yl)methyl phosphate synthase || 5,6,7,8-tetrahydromethanopterin hydro-lyase || Tryptophan synthase || Hydro-lyases |
| L-aspartase-like | 1 | INHERITED FROM: Fumarate hydratase || Hydro-lyases |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Duplex) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
54637,55718
54637 - Thioesterase/thiol ester dehydrase-isomerase
55718 - SCP-like | 0 | DIRECT |
143975,52016
143975 - IlvD/EDD N-terminal domain-like
52016 - LeuD/IlvD-like | 0 | DIRECT |
47413,55234
47413 - lambda repressor-like DNA-binding domains
55234 - Cyanase C-terminal domain | 0 | DIRECT |
46946,57716
46946 - S13-like H2TH domain
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
53639,56784
53639 - AraD/HMP-PK domain-like
56784 - HAD-like | 0 | DIRECT |
52016,53732
52016 - LeuD/IlvD-like
53732 - Aconitase iron-sulfur domain | 0 | DIRECT |
48600,53850
48600 - Chorismate mutase II
53850 - Periplasmic binding protein-like II | 0 | DIRECT |
48576,48576
48576 - Terpenoid synthases
48576 - Terpenoid synthases | 0 | DIRECT |
56796,55205
56796 - Dehydroquinate synthase-like
55205 - EPT/RTPC-like | 0 | DIRECT |
51735,54637
51735 - NAD(P)-binding Rossmann-fold domains
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
48179,48179
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
52151,51412
52151 - FabD/lysophospholipase-like
51412 - Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
74650,49863
74650 - Galactose mutarotase-like
49863 - Hyaluronate lyase-like, C-terminal domain | 0 | DIRECT |
51366,53686
51366 - Ribulose-phoshate binding barrel
53686 - Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
55205,52540
55205 - EPT/RTPC-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
56784,54211
56784 - HAD-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
48435,53955
48435 - Bacterial muramidases
53955 - Lysozyme-like | 0 | DIRECT |
53850,55021
53850 - Periplasmic binding protein-like II
55021 - ACT-like | 0 | DIRECT |
49785,48230
49785 - Galactose-binding domain-like
48230 - Chondroitin AC/alginate lyase | 0 | DIRECT |
52540,51569
52540 - P-loop containing nucleoside triphosphate hydrolases
51569 - Aldolase | 0 | DIRECT |
54211,54637
54211 - Ribosomal protein S5 domain 2-like
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
53686,54631
53686 - Tryptophan synthase beta subunit-like PLP-dependent enzymes
54631 - CBS-domain pair | 0 | DIRECT |
53697,46934
53697 - SIS domain
46934 - UBA-like | 0 | DIRECT |
49452,49785
49452 - Starch-binding domain-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
51569,53223
51569 - Aldolase
53223 - Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
54637,52151
54637 - Thioesterase/thiol ester dehydrase-isomerase
52151 - FabD/lysophospholipase-like | 0 | DIRECT |
54814,54821
54814 - Prokaryotic type KH domain (KH-domain type II)
54821 - Ribosomal protein S3 C-terminal domain | 0 | DIRECT |
48239,48576
48239 - Terpenoid cyclases/Protein prenyltransferases
48576 - Terpenoid synthases | 0 | DIRECT |
81624,46946
81624 - N-terminal domain of MutM-like DNA repair proteins
46946 - S13-like H2TH domain | 0 | DIRECT |
54211,54211
54211 - Ribosomal protein S5 domain 2-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
74778,52016
74778 - Aconitase B, N-terminal domain
52016 - LeuD/IlvD-like | 0 | DIRECT |
53732,52016
53732 - Aconitase iron-sulfur domain
52016 - LeuD/IlvD-like | 0 | DIRECT |
51569,51366
51569 - Aldolase
51366 - Ribulose-phoshate binding barrel | 0 | DIRECT |
48239,48239
48239 - Terpenoid cyclases/Protein prenyltransferases
48239 - Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
52096,51735
52096 - ClpP/crotonase
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
74650,49452
74650 - Galactose mutarotase-like
49452 - Starch-binding domain-like | 0 | DIRECT |
48230,74650
48230 - Chondroitin AC/alginate lyase
74650 - Galactose mutarotase-like | 0 | DIRECT |
64153,53613
64153 - YjeF N-terminal domain-like
53613 - Ribokinase-like | 0 | DIRECT |
54211,51366
54211 - Ribosomal protein S5 domain 2-like
51366 - Ribulose-phoshate binding barrel | 0 | DIRECT |
53850,53955
53850 - Periplasmic binding protein-like II
53955 - Lysozyme-like | 0 | DIRECT |
51735,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
54826,51604
54826 - Enolase N-terminal domain-like
51604 - Enolase C-terminal domain-like | 0 | DIRECT |
54637,54637
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0.00000000007867 | DIRECT |
55945,48150
55945 - TATA-box binding protein-like
48150 - DNA-glycosylase | 0.00000004063 | DIRECT |
47336,53474
47336 - ACP-like
53474 - alpha/beta-Hydrolases | 0.000004052 | DIRECT |
48179,52096
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
52096 - ClpP/crotonase | 0.000008787 | DIRECT |
51735,51735
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains | 0.00134 | INHERITED FROM: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase || Enoyl-CoA hydratase 2 || Hydro-lyases |
51735,47336
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like | 0.01076 | INHERITED FROM: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase |
53686,-9
53686 - Tryptophan synthase beta subunit-like PLP-dependent enzymes
-9 - PDB | 0.05572 | INHERITED FROM: Tryptophan synthase || Hydro-lyases |
52151,55048
52151 - FabD/lysophospholipase-like
55048 - Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0.1217 | INHERITED FROM: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase |
49723,48484
49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
48484 - Lipoxigenase | 0.2227 | INHERITED FROM: Hydroperoxy icosatetraenoate dehydratase |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0.5843 | INHERITED FROM: Acting on phosphates || 3-dehydroquinate dehydratase || 3-dehydroquinate synthase |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
54637,55718
54637 - Thioesterase/thiol ester dehydrase-isomerase
55718 - SCP-like | 0 | Direct |
143975,52016
143975 - IlvD/EDD N-terminal domain-like
52016 - LeuD/IlvD-like | 0 | Direct |
47413,55234
47413 - lambda repressor-like DNA-binding domains
55234 - Cyanase C-terminal domain | 0 | Direct |
46946,57716
46946 - S13-like H2TH domain
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
53639,56784
53639 - AraD/HMP-PK domain-like
56784 - HAD-like | 0 | Direct |
52016,53732
52016 - LeuD/IlvD-like
53732 - Aconitase iron-sulfur domain | 0 | Direct |
48600,53850
48600 - Chorismate mutase II
53850 - Periplasmic binding protein-like II | 0 | Direct |
48576,48576
48576 - Terpenoid synthases
48576 - Terpenoid synthases | 0 | Direct |
56796,55205
56796 - Dehydroquinate synthase-like
55205 - EPT/RTPC-like | 0 | Direct |
51735,54637
51735 - NAD(P)-binding Rossmann-fold domains
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
48179,48179
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
52151,51412
52151 - FabD/lysophospholipase-like
51412 - Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
74650,49863
74650 - Galactose mutarotase-like
49863 - Hyaluronate lyase-like, C-terminal domain | 0 | Direct |
51366,53686
51366 - Ribulose-phoshate binding barrel
53686 - Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
55205,52540
55205 - EPT/RTPC-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
56784,54211
56784 - HAD-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
48435,53955
48435 - Bacterial muramidases
53955 - Lysozyme-like | 0 | Direct |
53850,55021
53850 - Periplasmic binding protein-like II
55021 - ACT-like | 0 | Direct |
49785,48230
49785 - Galactose-binding domain-like
48230 - Chondroitin AC/alginate lyase | 0 | Direct |
52540,51569
52540 - P-loop containing nucleoside triphosphate hydrolases
51569 - Aldolase | 0 | Direct |
54211,54637
54211 - Ribosomal protein S5 domain 2-like
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
53686,54631
53686 - Tryptophan synthase beta subunit-like PLP-dependent enzymes
54631 - CBS-domain pair | 0 | Direct |
53697,46934
53697 - SIS domain
46934 - UBA-like | 0 | Direct |
49452,49785
49452 - Starch-binding domain-like
49785 - Galactose-binding domain-like | 0 | Direct |
51569,53223
51569 - Aldolase
53223 - Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
54637,52151
54637 - Thioesterase/thiol ester dehydrase-isomerase
52151 - FabD/lysophospholipase-like | 0 | Direct |
54814,54821
54814 - Prokaryotic type KH domain (KH-domain type II)
54821 - Ribosomal protein S3 C-terminal domain | 0 | Direct |
48239,48576
48239 - Terpenoid cyclases/Protein prenyltransferases
48576 - Terpenoid synthases | 0 | Direct |
81624,46946
81624 - N-terminal domain of MutM-like DNA repair proteins
46946 - S13-like H2TH domain | 0 | Direct |
54211,54211
54211 - Ribosomal protein S5 domain 2-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
74778,52016
74778 - Aconitase B, N-terminal domain
52016 - LeuD/IlvD-like | 0 | Direct |
53732,52016
53732 - Aconitase iron-sulfur domain
52016 - LeuD/IlvD-like | 0 | Direct |
51569,51366
51569 - Aldolase
51366 - Ribulose-phoshate binding barrel | 0 | Direct |
48239,48239
48239 - Terpenoid cyclases/Protein prenyltransferases
48239 - Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
52096,51735
52096 - ClpP/crotonase
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
74650,49452
74650 - Galactose mutarotase-like
49452 - Starch-binding domain-like | 0 | Direct |
48230,74650
48230 - Chondroitin AC/alginate lyase
74650 - Galactose mutarotase-like | 0 | Direct |
64153,53613
64153 - YjeF N-terminal domain-like
53613 - Ribokinase-like | 0 | Direct |
54211,51366
54211 - Ribosomal protein S5 domain 2-like
51366 - Ribulose-phoshate binding barrel | 0 | Direct |
53850,53955
53850 - Periplasmic binding protein-like II
53955 - Lysozyme-like | 0 | Direct |
51735,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
54826,51604
54826 - Enolase N-terminal domain-like
51604 - Enolase C-terminal domain-like | 0 | Direct |
54637,54637
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0.00000000007867 | Direct |
55945,48150
55945 - TATA-box binding protein-like
48150 - DNA-glycosylase | 0.00000004063 | Direct |
47336,53474
47336 - ACP-like
53474 - alpha/beta-Hydrolases | 0.000004052 | Direct |
48179,52096
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
52096 - ClpP/crotonase | 0.000008787 | Direct |
51735,51735
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains | 0.00134 | Inherited |
51735,47336
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like | 0.01076 | Inherited |
53686,-9
53686 - Tryptophan synthase beta subunit-like PLP-dependent enzymes
-9 - PDB | 0.05572 | Inherited |
52151,55048
52151 - FabD/lysophospholipase-like
55048 - Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0.1217 | Inherited |
49723,48484
49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
48484 - Lipoxigenase | 0.2227 | Inherited |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0.5843 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Triple) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
48239,48239,48576
48239 - Terpenoid cyclases/Protein prenyltransferases
48239 - Terpenoid cyclases/Protein prenyltransferases
48576 - Terpenoid synthases | 0 | DIRECT |
52096,51735,48179
52096 - ClpP/crotonase
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
56784,54211,54211
56784 - HAD-like
54211 - Ribosomal protein S5 domain 2-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
49785,48230,74650
49785 - Galactose-binding domain-like
48230 - Chondroitin AC/alginate lyase
74650 - Galactose mutarotase-like | 0 | DIRECT |
74778,52016,53732
74778 - Aconitase B, N-terminal domain
52016 - LeuD/IlvD-like
53732 - Aconitase iron-sulfur domain | 0 | DIRECT |
51735,48179,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
51735,51735,54637
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
81624,46946,57716
81624 - N-terminal domain of MutM-like DNA repair proteins
46946 - S13-like H2TH domain
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
55205,52540,51569
55205 - EPT/RTPC-like
52540 - P-loop containing nucleoside triphosphate hydrolases
51569 - Aldolase | 0 | DIRECT |
74650,49452,49785
74650 - Galactose mutarotase-like
49452 - Starch-binding domain-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
48600,53850,55021
48600 - Chorismate mutase II
53850 - Periplasmic binding protein-like II
55021 - ACT-like | 0 | DIRECT |
51735,54637,54637
51735 - NAD(P)-binding Rossmann-fold domains
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
51569,53223,51735
51569 - Aldolase
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
48230,74650,49863
48230 - Chondroitin AC/alginate lyase
74650 - Galactose mutarotase-like
49863 - Hyaluronate lyase-like, C-terminal domain | 0 | DIRECT |
52540,51569,53223
52540 - P-loop containing nucleoside triphosphate hydrolases
51569 - Aldolase
53223 - Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
54637,54637,55718
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase
55718 - SCP-like | 0 | DIRECT |
54211,54211,54637
54211 - Ribosomal protein S5 domain 2-like
54211 - Ribosomal protein S5 domain 2-like
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
56796,55205,52540
56796 - Dehydroquinate synthase-like
55205 - EPT/RTPC-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51735,47336,53474
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like
53474 - alpha/beta-Hydrolases | 0.00000002438 | DIRECT |
48179,48179,52096
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
52096 - ClpP/crotonase | 0.000008787 | DIRECT |
50129,51735,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains | 0.0001664 | DIRECT |
51735,51735,47336
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like | 0.007012 | INHERITED FROM: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
48239,48239,48576
48239 - Terpenoid cyclases/Protein prenyltransferases
48239 - Terpenoid cyclases/Protein prenyltransferases
48576 - Terpenoid synthases | 0 | Direct |
52096,51735,48179
52096 - ClpP/crotonase
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
56784,54211,54211
56784 - HAD-like
54211 - Ribosomal protein S5 domain 2-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
49785,48230,74650
49785 - Galactose-binding domain-like
48230 - Chondroitin AC/alginate lyase
74650 - Galactose mutarotase-like | 0 | Direct |
74778,52016,53732
74778 - Aconitase B, N-terminal domain
52016 - LeuD/IlvD-like
53732 - Aconitase iron-sulfur domain | 0 | Direct |
51735,48179,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
51735,51735,54637
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
81624,46946,57716
81624 - N-terminal domain of MutM-like DNA repair proteins
46946 - S13-like H2TH domain
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
55205,52540,51569
55205 - EPT/RTPC-like
52540 - P-loop containing nucleoside triphosphate hydrolases
51569 - Aldolase | 0 | Direct |
74650,49452,49785
74650 - Galactose mutarotase-like
49452 - Starch-binding domain-like
49785 - Galactose-binding domain-like | 0 | Direct |
48600,53850,55021
48600 - Chorismate mutase II
53850 - Periplasmic binding protein-like II
55021 - ACT-like | 0 | Direct |
51735,54637,54637
51735 - NAD(P)-binding Rossmann-fold domains
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
51569,53223,51735
51569 - Aldolase
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
48230,74650,49863
48230 - Chondroitin AC/alginate lyase
74650 - Galactose mutarotase-like
49863 - Hyaluronate lyase-like, C-terminal domain | 0 | Direct |
52540,51569,53223
52540 - P-loop containing nucleoside triphosphate hydrolases
51569 - Aldolase
53223 - Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
54637,54637,55718
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase
55718 - SCP-like | 0 | Direct |
54211,54211,54637
54211 - Ribosomal protein S5 domain 2-like
54211 - Ribosomal protein S5 domain 2-like
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
56796,55205,52540
56796 - Dehydroquinate synthase-like
55205 - EPT/RTPC-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51735,47336,53474
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like
53474 - alpha/beta-Hydrolases | 0.00000002438 | Direct |
48179,48179,52096
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
52096 - ClpP/crotonase | 0.000008787 | Direct |
50129,51735,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains | 0.0001664 | Direct |
51735,51735,47336
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like | 0.007012 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Plot distribution on species Tree Of Life (sTOL) for Superfamily and/or Family domains annotated by this EC term
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Plot tree as:
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Download Newick format tree:
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( show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domain
architecture data for all genomes in SUPERFAMILY. The PAUP
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
Plot distribution on species Tree Of Life (sTOL) for single supra-domains annotated by this EC term
|
Plot tree as:
| |
Download Newick format tree:
| |
Browsing in TREE OF LIFE:
|
( show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
|
|
> BO Hierarchy > Carbon-oxygen lyases
