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CTD Chemicals (CC): Arsenicals 
(show info)
Biomedical Ontology
Like Gene Ontology (GO), biomedical ontology such as phenotype ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Biomedical ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI’s thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology Based on YP which is the major contributor to the ‘Ascomycete phenotype ontology’, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- UniProtKB KeyWords (KW) Ontology Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- CTD Diseases (CD) Ontology CD is MEDIC disease vocabulary that is modified by CTD from the "Diseases" [C] branch of Medical Subject Headings (MeSH), combined with genetic disorders from the Online Mendelian Inheritance in OMIM database.
- CTD Chemicals (CC) Ontology CC is chemical vocabulary that is adapted by CTD from the "Chemicals and Drugs" category and Supplementary Concept Records of Medical Subject Headings (MeSH, a hierarchical vocabulary used to index articles for MEDLINE/PubMed).
Jump to [ Top · Hierarchy · Annotations ]
Root: CC Hierarchy (CTD chemicals from Comparative Toxicogenomics Database)
| Shortest distance to current term (+ for parents, - for children) |
CC term [CC ID] <#Children> |
#Domains (Superfamily|Family) |
#Supra-domain (Single|Duplex|Triple) |
| + + 2: | Chemicals [MESH:D] <13> |
| + 1: | Organic Chemicals [MESH:D009930] <621> | (617|829) |
(620|532|254) |
| + 1: | Inorganic Chemicals [MESH:D007287] <48> | (506|690) |
(514|450|213) |
| 0: | Arsenicals [MESH:D001152] <152> | (61|86) |
(65|65|36) |
| - 1: | Arsenates [MESH:D001149] <19> | (3|5) |
(4|3|0) |
| - 1: | Arsanilic Acid [MESH:D001147] <7> | (0|0) |
(0|0|0) |
| - 1: | Arsenites [MESH:D018053] <7> | (26|31) |
(29|18|16) |
| - 1: | Cacodylic Acid [MESH:D002101] <7> | (7|9) |
(9|3|0) |
| - 1: | Arsenazo III [MESH:D001150] <4> | (0|0) |
(0|0|0) |
| - 1: | p-Azobenzenearsonate [MESH:D010132] <4> | (0|0) |
(0|0|0) |
| - 1: | Arsphenamine [MESH:D001153] <1> | (0|0) |
(0|0|0) |
| - 1: | 1-S-dimethylarsino-1-thio-beta-D-glucopyranoside [MESH:C026637] | (0|0) |
(0|0|0) |
| - 1: | 1-naphthylarsonic acid [MESH:C574937] | (0|0) |
(0|0|0) |
| - 1: | 10,10'-oxybisphenoxarsine [MESH:C499044] | (0|0) |
(0|0|0) |
| - 1: | 2,3,4-trihydroxybutylarsonic acid [MESH:C523361] | (0|0) |
(0|0|0) |
| - 1: | 2,3-dihydroxybutane-1,4-bis(arsonic acid) [MESH:C523362] | (0|0) |
(0|0|0) |
| - 1: | 2-(4-aminophenyl)-1,3,2-dithiarsinane [MESH:C000591344] | (0|0) |
(0|0|0) |
| - 1: | 2-aminoethylarsonic acid [MESH:C060619] | (0|0) |
(0|0|0) |
| - 1: | 2-chlorovinylarsine oxide [MESH:C063691] | (0|0) |
(0|0|0) |
| - 1: | 2-chlorovinylarsonous acid [MESH:C419383] | (0|0) |
(0|0|0) |
| - 1: | 2-hydroxy-3-sulfoxypropyl 5-(2-carboxy-3-((2,3-dihydroxypropoxy)propyl)dimethylarseno)-5-deoxyribofu [MESH:C413737] | (0|0) |
(0|0|0) |
| - 1: | 2-p-aminophenyl-1,3,2-dithiarsenolane [MESH:C000600810] | (0|0) |
(0|0|0) |
| - 1: | 2-phenyl-((1,3,2)dithiarsolan-4-yl)-methanol [MESH:C521278] | (0|0) |
(0|0|0) |
| - 1: | 2-phenylene-bis-dimethylarsine [MESH:C041937] | (0|0) |
(0|0|0) |
| - 1: | 3,4-dihydroxybutylarsonic acid [MESH:C095814] | (0|0) |
(0|0|0) |
| - 1: | 3-(2,6-dibromo-4-sulfophenylazo)-6-(2-arsenophenylazo)-4,5-dihydroxynaphthalene-2,7-disulfonic acid [MESH:C534149] | (0|0) |
(0|0|0) |
| - 1: | 3-aminopropylarsonic acid [MESH:C076738] | (0|0) |
(0|0|0) |
| - 1: | 3-arsono-2-(hydroxymethyl)propanoic acid [MESH:C094717] | (0|0) |
(0|0|0) |
| - 1: | 3-arsonoalanine [MESH:C082448] | (0|0) |
(0|0|0) |
| - 1: | 3-arsonopyruvate [MESH:C102551] | (0|0) |
(0|0|0) |
| - 1: | 3-o-chlorophenyl-5-(2'-arsenoxylphenylazo)rhodanine [MESH:C539725] | (0|0) |
(0|0|0) |
| - 1: | 4',5'-bis(1,2,3-dithioarsolan-2-yl)fluorescein-5-carboxylic acid [MESH:C000613298] | (0|0) |
(0|0|0) |
| - 1: | 4-((bromoacetyl)amino)phenyl arsenoxide [MESH:C031672] | (0|0) |
(0|0|0) |
| - 1: | 4-(4-aminophenylazo)phenylarsonic acid [MESH:C013807] | (0|0) |
(0|0|0) |
| - 1: | 4-(4-bromoacetylphenylazoamide)phenylarsonic acid [MESH:C006807] | (0|0) |
(0|0|0) |
| - 1: | 4-(N-(4-azido-2-nitrophenyl)aminoacetamido)phenylarsine oxide [MESH:C110916] | (0|0) |
(0|0|0) |
| - 1: | 4-(N-(S-glutathionylacetyl)amino)phenylarsenoxide [MESH:C426645] | (0|0) |
(0|0|0) |
| - 1: | 4-(dansylamino)phenylarsenoxide [MESH:C417263] | (0|0) |
(0|0|0) |
| - 1: | 4-(hydroxybutyl)dichloroarsine [MESH:C052184] | (0|0) |
(0|0|0) |
| - 1: | 4-aminophenylarsenoxide [MESH:C032642] | (5|4) |
(6|1|0) |
| - 1: | 4-aminophenyldichloroarsine [MESH:C053801] | (0|0) |
(0|0|0) |
| - 1: | 4-hydroxy-3-aminophenylarsonic acid [MESH:C511221] | (0|0) |
(0|0|0) |
| - 1: | 4-iodophenylarsine oxide [MESH:C075599] | (0|0) |
(0|0|0) |
| - 1: | 5'-dimethylarsinoyladenosine [MESH:C490151] | (0|0) |
(0|0|0) |
| - 1: | Arsenamide [MESH:D001148] | (0|0) |
(0|0|0) |
| - 1: | Arsenic Trioxide [MESH:D000077237] | (10|18) |
(13|11|7) |
| - 1: | Arsenicum Album-200 [MESH:C488405] | (0|0) |
(0|0|0) |
| - 1: | AsCy3 compound [MESH:C000597252] | (0|0) |
(0|0|0) |
| - 1: | Clark 1 [MESH:C098345] | (0|0) |
(0|0|0) |
| - 1: | Clark 2 [MESH:C098346] | (0|0) |
(0|0|0) |
| - 1: | F151 [MESH:C013747] | (0|0) |
(0|0|0) |
| - 1: | IMOL 881 [MESH:C084448] | (0|0) |
(0|0|0) |
| - 1: | Mel T [MESH:C087030] | (0|0) |
(0|0|0) |
| - 1: | Melarsoprol [MESH:D008549] | (1|1) |
(1|0|0) |
| - 1: | N-(4-(1,3,2)dithiarsolan-2-yl-phenyl)hexahydro-2-oxo-(3aS,4S,6aR)-1H-trieno(3,4-d)imidazole-4-pentam [MESH:C530735] | (0|0) |
(0|0|0) |
| - 1: | N-(bromoacetyl)-3-((4-arsonophenyl)azo)tyrosine [MESH:C030301] | (0|0) |
(0|0|0) |
| - 1: | NSC48300 [MESH:C571012] | (0|0) |
(0|0|0) |
| - 1: | Navjeenan [MESH:C083969] | (0|0) |
(0|0|0) |
| - 1: | R 7-45 [MESH:C065461] | (0|0) |
(0|0|0) |
| - 1: | ReAsH-EDT2 compound [MESH:C454115] | (0|0) |
(0|0|0) |
| - 1: | Roxarsone [MESH:D012406] | (1|0) |
(1|1|1) |
| - 1: | S-dimethylaminoarsino-thiosuccinic acid [MESH:C552033] | (0|0) |
(0|0|0) |
| - 1: | V5851 [MESH:C013768] | (0|0) |
(0|0|0) |
| - 1: | Valpani [MESH:C083967] | (0|0) |
(0|0|0) |
| - 1: | acetarsol [MESH:C005284] | (0|0) |
(0|0|0) |
| - 1: | acetarsol, dimethicone, neomycin, nystatin, polymyxin drug combination [MESH:C006119] | (0|0) |
(0|0|0) |
| - 1: | acetylaminophenylarsine oxide [MESH:C065413] | (0|0) |
(0|0|0) |
| - 1: | acetylarsenocholine [MESH:C035463] | (0|0) |
(0|0|0) |
| - 1: | arsabenzene [MESH:C519089] | (0|0) |
(0|0|0) |
| - 1: | arsacetyl [MESH:C469857] | (0|0) |
(0|0|0) |
| - 1: | arsenic disulfide [MESH:C058317] | (2|2) |
(2|0|0) |
| - 1: | arsenic pentafluoride [MESH:C049320] | (0|0) |
(0|0|0) |
| - 1: | arsenic pentoxide [MESH:C042120] | (0|0) |
(0|0|0) |
| - 1: | arsenic trichloride [MESH:C050510] | (0|0) |
(0|0|0) |
| - 1: | arsenic triiodide [MESH:C530601] | (0|0) |
(0|0|0) |
| - 1: | arsenic trisulfide [MESH:C045816] | (0|0) |
(0|0|0) |
| - 1: | arsenicin A [MESH:C517594] | (0|0) |
(0|0|0) |
| - 1: | arsenicum album-30 [MESH:C121243] | (0|0) |
(0|0|0) |
| - 1: | arsenobetaine [MESH:C038992] | (0|0) |
(0|0|0) |
| - 1: | arsenocholine [MESH:C039920] | (0|0) |
(0|0|0) |
| - 1: | arsenophenylglycine [MESH:C014751] | (0|0) |
(0|0|0) |
| - 1: | arsenopyrite [MESH:C064510] | (0|0) |
(0|0|0) |
| - 1: | arsenotriglutathione [MESH:C093363] | (0|0) |
(0|0|0) |
| - 1: | arsenous carbonate [MESH:C049895] | (0|0) |
(0|0|0) |
| - 1: | arsine [MESH:C006633] | (0|0) |
(0|0|0) |
| - 1: | arsonate tyrosine [MESH:C012753] | (0|0) |
(0|0|0) |
| - 1: | arsonic acid [MESH:C054806] | (0|0) |
(0|0|0) |
| - 1: | arsonoacetic acid [MESH:C033355] | (0|0) |
(0|0|0) |
| - 1: | arsonomethylphosphonic acid [MESH:C023528] | (0|0) |
(0|0|0) |
| - 1: | arsthinol [MESH:C546471] | (0|0) |
(0|0|0) |
| - 1: | austinite [MESH:C000598706] | (0|0) |
(0|0|0) |
| - 1: | benzenearsonic acid [MESH:C020979] | (0|0) |
(0|0|0) |
| - 1: | compound E (Friedheim) [MESH:C018022] | (0|0) |
(0|0|0) |
| - 1: | darinaparsin [MESH:C515055] | (6|6) |
(6|3|1) |
| - 1: | dimethylarsine [MESH:C062856] | (2|2) |
(2|1|0) |
| - 1: | dimethylarsino-cysteine [MESH:C587955] | (0|0) |
(0|0|0) |
| - 1: | dimethylarsinomercaptoethanol [MESH:C044975] | (0|0) |
(0|0|0) |
| - 1: | dimethylarsinopenicillamine [MESH:C044974] | (0|0) |
(0|0|0) |
| - 1: | dimethylarsinoylacetic acid [MESH:C477455] | (0|0) |
(0|0|0) |
| - 1: | dimethylthioarsinic acid [MESH:C547156] | (0|0) |
(0|0|0) |
| - 1: | dimethylthioarsinic anhydride [MESH:C520159] | (0|0) |
(0|0|0) |
| - 1: | dinitrophenyl-6-aminocaproyltyrosylazobenzene-4-arsonate [MESH:C007492] | (0|0) |
(0|0|0) |
| - 1: | dipalmitoylphosphatidylarsenocholine [MESH:C561216] | (0|0) |
(0|0|0) |
| - 1: | diphenylarsinic acid [MESH:C493087] | (0|0) |
(0|0|0) |
| - 1: | diphenylthioarsinic acid [MESH:C000594118] | (0|0) |
(0|0|0) |
| - 1: | diphetarsone [MESH:C037924] | (0|0) |
(0|0|0) |
| - 1: | drocarbil [MESH:C028308] | (0|0) |
(0|0|0) |
| - 1: | ferric methanearsonate [MESH:C016449] | (0|0) |
(0|0|0) |
| - 1: | gallium arsenide [MESH:C043055] | (0|0) |
(0|0|0) |
| - 1: | indium arsenide [MESH:C076773] | (0|0) |
(0|0|0) |
| - 1: | lewisite [MESH:C035965] | (0|0) |
(0|0|0) |
| - 1: | melaminylthioarsenate [MESH:C062789] | (0|0) |
(0|0|0) |
| - 1: | melarsen [MESH:C008345] | (0|0) |
(0|0|0) |
| - 1: | melarsen oxide [MESH:C044719] | (0|0) |
(0|0|0) |
| - 1: | melarsomine [MESH:C076253] | (0|0) |
(0|0|0) |
| - 1: | melarsonic acid [MESH:C015980] | (0|0) |
(0|0|0) |
| - 1: | methanearsonous acid [MESH:C046653] | (0|0) |
(0|0|0) |
| - 1: | methylarsenic diglutathione [MESH:C571174] | (0|0) |
(0|0|0) |
| - 1: | methylarsine [MESH:C543395] | (0|0) |
(0|0|0) |
| - 1: | methylarsine oxide [MESH:C080197] | (2|2) |
(2|1|0) |
| - 1: | methyldichloroarsine [MESH:C074483] | (0|0) |
(0|0|0) |
| - 1: | methylenediarsonic acid [MESH:C023529] | (0|0) |
(0|0|0) |
| - 1: | mimetite [MESH:C560237] | (0|0) |
(0|0|0) |
| - 1: | monomethylarsonic acid [MESH:C020300] | (1|0) |
(2|0|0) |
| - 1: | monomethylmonothioarsonic acid [MESH:C552934] | (0|0) |
(0|0|0) |
| - 1: | nickel arsenide [MESH:C038376] | (0|0) |
(0|0|0) |
| - 1: | nitarsone [MESH:C015389] | (0|0) |
(0|0|0) |
| - 1: | oxophenarsine [MESH:C100059] | (0|0) |
(0|0|0) |
| - 1: | oxophenylarsine [MESH:C029341] | (4|3) |
(4|0|0) |
| - 1: | p-aminophenylarsine oxide [MESH:C530734] | (0|0) |
(0|0|0) |
| - 1: | p-azidophenylarsenoxide [MESH:C000628142] | (0|0) |
(0|0|0) |
| - 1: | phenarsazine chloride [MESH:C010283] | (0|0) |
(0|0|0) |
| - 1: | phenarsazine oxide [MESH:C017615] | (0|0) |
(0|0|0) |
| - 1: | phenoxarsine oxide [MESH:C017617] | (0|0) |
(0|0|0) |
| - 1: | phenylarsane [MESH:C521509] | (0|0) |
(0|0|0) |
| - 1: | phenylarsonous acid [MESH:C046652] | (0|0) |
(0|0|0) |
| - 1: | phenyldichloroarsine [MESH:C053663] | (0|0) |
(0|0|0) |
| - 1: | polyanilineTi(IV)arsenophosphate [MESH:C000592031] | (0|0) |
(0|0|0) |
| - 1: | qinghuang [MESH:C570774] | (0|0) |
(0|0|0) |
| - 1: | scorodite [MESH:C548094] | (0|0) |
(0|0|0) |
| - 1: | spiroarsorane I [MESH:C102882] | (0|0) |
(0|0|0) |
| - 1: | spiroarsorane II [MESH:C102883] | (0|0) |
(0|0|0) |
| - 1: | spiroarsorane III [MESH:C102884] | (0|0) |
(0|0|0) |
| - 1: | spirotrypan [MESH:C009306] | (0|0) |
(0|0|0) |
| - 1: | technetium Tc 99m 15-(bis(3,4-dimethyl arsino)phenyl)pentadecanoic acid [MESH:C054747] | (0|0) |
(0|0|0) |
| - 1: | tetraarsenic tetrasulfide [MESH:C534735] | (3|3) |
(3|3|1) |
| - 1: | tetramethylarsonium [MESH:C064748] | (0|0) |
(0|0|0) |
| - 1: | tetraphenylarsonium [MESH:C009439] | (0|0) |
(0|0|0) |
| - 1: | tetraphenylarsonium oxotechnetiumbis(ethanedithiolate) [MESH:C024228] | (0|0) |
(0|0|0) |
| - 1: | thoron (reagent) [MESH:C012578] | (0|0) |
(0|0|0) |
| - 1: | toluene-3,4-dithiolatoarsenic(III) [MESH:C578322] | (0|0) |
(0|0|0) |
| - 1: | trimethylarsine [MESH:C009572] | (0|0) |
(0|0|0) |
| - 1: | trimethylarsine oxide [MESH:C052920] | (0|0) |
(0|0|0) |
| - 1: | triphenylarsine [MESH:C000613766] | (2|2) |
(2|1|0) |
| - 1: | tryparsamide [MESH:C073345] | (0|0) |
(0|0|0) |
| - 1: | urbacid [MESH:C049110] | (0|0) |
(0|0|0) |
Jump to [ Top · Hierarchy ]
Family( show details)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| p53 tetramerization domain | 0 | DIRECT |
| Caspase catalytic domain | 0 | DIRECT |
| Serine carboxypeptidase-like | 0 | DIRECT |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | DIRECT |
| LON domain-like | 0 | DIRECT |
| Ferritin | 0 | DIRECT |
| Methyl-CpG-binding domain, MBD | 0 | DIRECT |
| DNA gyrase/MutL, N-terminal domain | 0 | DIRECT |
| S-adenosylhomocystein hydrolase | 0 | DIRECT |
| alpha-catenin/vinculin | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Arginase-like amidino hydrolases | 0 | DIRECT |
| P-domain of calnexin/calreticulin | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| E2F dimerization segment | 0 | DIRECT |
| Platelet-derived growth factor-like | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| p53 DNA-binding domain-like | 0 | DIRECT |
| Apolipoprotein A-I | 0 | DIRECT |
| (Glycosyl)asparaginase | 0 | DIRECT |
| Homocysteine S-methyltransferase | 0 | DIRECT |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | DIRECT |
| Retinoblastoma tumor suppressor domains | 0 | DIRECT |
| Serum albumin-like | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Nitric oxide (NO) synthase oxygenase domain | 0 | DIRECT |
| Calnexin/calreticulin | 0 | DIRECT |
| PCI domain (PINT motif) | 0 | DIRECT |
| N-terminal domain of cbl (N-cbl) | 0 | DIRECT |
| L-aspartase/fumarase | 0 | DIRECT |
| Variant SAM domain | 0 | DIRECT |
| Hsp90 middle domain | 0 | DIRECT |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | DIRECT |
| SMAD domain | 0 | DIRECT |
| DNA gyrase/MutL, second domain | 0 | DIRECT |
| Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | DIRECT |
| TNF receptor-like | 0.0000005502 | DIRECT |
| Leucine zipper domain | 0.00001857 | DIRECT |
| Protein kinases, catalytic subunit | 0.00004916 | DIRECT |
| DEATH domain, DD | 0.00008819 | DIRECT |
| Interleukin 8-like chemokines | 0.0001169 | DIRECT |
| Thyroglobulin type-1 domain | 0.0002153 | DIRECT |
| SH2 domain | 0.0004101 | DIRECT |
| Metallothionein | 0.0004922 | DIRECT |
| Integrin A (or I) domain | 0.0005245 | DIRECT |
| Integrin domains | 0.0005266 | DIRECT |
| Integrin alpha N-terminal domain | 0.0005273 | DIRECT |
| Caspase recruitment domain, CARD | 0.0005273 | DIRECT |
| Nuclear receptor ligand-binding domain | 0.0006456 | DIRECT |
| Serpins | 0.0008123 | DIRECT |
| Complement control module/SCR domain | 0.0008338 | DIRECT |
| Nuclear receptor | 0.001563 | INHERITED FROM: triphenylarsine |
| Ovomucoid domain III-like | 0.001719 | INHERITED FROM: Arsenites |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.002096 | INHERITED FROM: Arsenic Trioxide || sodium arsenite || darinaparsin |
| Laminin G-like module | 0.002147 | INHERITED FROM: Arsenites |
| A DNA-binding domain in eukaryotic transcription factors | 0.002888 | INHERITED FROM: dimethylarsine || Arsenites || methylarsine oxide |
| MMP N-terminal domain | 0.003196 | INHERITED FROM: Cacodylic Acid || dimethylarsinous acid |
| Hemopexin-like domain | 0.006755 | INHERITED FROM: dimethylarsinous acid |
| Homeodomain | 0.01039 | INHERITED FROM: arsenite || Arsenites |
| Cell cycle transcription factor e2f-dp | 0.01095 | INHERITED FROM: Arsenic Trioxide |
| Nucleosome core histones | 0.0133 | INHERITED FROM: dimethylarsinous acid |
| L domain | 0.0169 | INHERITED FROM: sodium arsenite |
| Netrin-like domain (NTR/C345C module) | 0.03274 | INHERITED FROM: Arsenic Trioxide |
| Aldo-keto reductases (NADP) | 0.03478 | INHERITED FROM: 4-aminophenylarsenoxide |
| Cytochrome P450 | 0.0394 | INHERITED FROM: Melarsoprol |
| Ephrin receptor ligand binding domain | 0.04349 | INHERITED FROM: Arsenates |
| Bcl-2 inhibitors of programmed cell death | 0.04349 | INHERITED FROM: arsenic disulfide || Arsenic Trioxide || Cacodylic Acid |
| HLH, helix-loop-helix DNA-binding domain | 0.0529 | INHERITED FROM: arsenite |
| Matrix metalloproteases, catalytic domain | 0.05576 | INHERITED FROM: Cacodylic Acid || dimethylarsinous acid |
| Hexokinase | 0.06202 | INHERITED FROM: 4-aminophenylarsenoxide |
| Cyclin | 0.0634 | INHERITED FROM: tetraarsenic tetrasulfide |
| Long-chain cytokines | 0.06843 | INHERITED FROM: oxophenylarsine |
| Frizzled cysteine-rich domain | 0.07213 | INHERITED FROM: Arsenates |
| Fibronectin type II module | 0.09773 | INHERITED FROM: Cacodylic Acid || dimethylarsinous acid |
| Cadherin | 0.1128 | INHERITED FROM: arsenite |
| HSP40/DnaJ peptide-binding domain | 0.1348 | INHERITED FROM: darinaparsin |
| FAD/NAD-linked reductases, N-terminal and central domains | 0.1744 | INHERITED FROM: Arsenates |
| Actin/HSP70 | 0.236 | INHERITED FROM: darinaparsin |
| PDI-like | 0.3407 | INHERITED FROM: tetraarsenic tetrasulfide |
| Carbonic anhydrase | 0.5276 | INHERITED FROM: Cacodylic Acid |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0.5793 | INHERITED FROM: Arsenates |
| Chaperone J-domain | 0.8411 | INHERITED FROM: darinaparsin |
| Forkhead DNA-binding domain | 0.8631 | INHERITED FROM: arsenite |
| Tetratricopeptide repeat (TPR) | 0.9262 | INHERITED FROM: 4-aminophenylarsenoxide |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| p53 tetramerization domain | 0 | Direct |
| Caspase catalytic domain | 0 | Direct |
| Serine carboxypeptidase-like | 0 | Direct |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | Direct |
| LON domain-like | 0 | Direct |
| Ferritin | 0 | Direct |
| Methyl-CpG-binding domain, MBD | 0 | Direct |
| DNA gyrase/MutL, N-terminal domain | 0 | Direct |
| S-adenosylhomocystein hydrolase | 0 | Direct |
| alpha-catenin/vinculin | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Arginase-like amidino hydrolases | 0 | Direct |
| P-domain of calnexin/calreticulin | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| E2F dimerization segment | 0 | Direct |
| Platelet-derived growth factor-like | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| p53 DNA-binding domain-like | 0 | Direct |
| Apolipoprotein A-I | 0 | Direct |
| (Glycosyl)asparaginase | 0 | Direct |
| Homocysteine S-methyltransferase | 0 | Direct |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | Direct |
| Retinoblastoma tumor suppressor domains | 0 | Direct |
| Serum albumin-like | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Nitric oxide (NO) synthase oxygenase domain | 0 | Direct |
| Calnexin/calreticulin | 0 | Direct |
| PCI domain (PINT motif) | 0 | Direct |
| N-terminal domain of cbl (N-cbl) | 0 | Direct |
| L-aspartase/fumarase | 0 | Direct |
| Variant SAM domain | 0 | Direct |
| Hsp90 middle domain | 0 | Direct |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | Direct |
| SMAD domain | 0 | Direct |
| DNA gyrase/MutL, second domain | 0 | Direct |
| Cell cycle control phosphatase, catalytic domain | 0 | Direct |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | Direct |
| TNF receptor-like | 0.0000005502 | Direct |
| Leucine zipper domain | 0.00001857 | Direct |
| Protein kinases, catalytic subunit | 0.00004916 | Direct |
| DEATH domain, DD | 0.00008819 | Direct |
| Interleukin 8-like chemokines | 0.0001169 | Direct |
| Thyroglobulin type-1 domain | 0.0002153 | Direct |
| SH2 domain | 0.0004101 | Direct |
| Metallothionein | 0.0004922 | Direct |
| Integrin A (or I) domain | 0.0005245 | Direct |
| Integrin domains | 0.0005266 | Direct |
| Integrin alpha N-terminal domain | 0.0005273 | Direct |
| Caspase recruitment domain, CARD | 0.0005273 | Direct |
| Nuclear receptor ligand-binding domain | 0.0006456 | Direct |
| Serpins | 0.0008123 | Direct |
| Complement control module/SCR domain | 0.0008338 | Direct |
| Nuclear receptor | 0.001563 | Inherited |
| Ovomucoid domain III-like | 0.001719 | Inherited |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.002096 | Inherited |
| Laminin G-like module | 0.002147 | Inherited |
| A DNA-binding domain in eukaryotic transcription factors | 0.002888 | Inherited |
| MMP N-terminal domain | 0.003196 | Inherited |
| Hemopexin-like domain | 0.006755 | Inherited |
| Homeodomain | 0.01039 | Inherited |
| Cell cycle transcription factor e2f-dp | 0.01095 | Inherited |
| Nucleosome core histones | 0.0133 | Inherited |
| L domain | 0.0169 | Inherited |
| Netrin-like domain (NTR/C345C module) | 0.03274 | Inherited |
| Aldo-keto reductases (NADP) | 0.03478 | Inherited |
| Cytochrome P450 | 0.0394 | Inherited |
| Ephrin receptor ligand binding domain | 0.04349 | Inherited |
| Bcl-2 inhibitors of programmed cell death | 0.04349 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.0529 | Inherited |
| Matrix metalloproteases, catalytic domain | 0.05576 | Inherited |
| Hexokinase | 0.06202 | Inherited |
| Cyclin | 0.0634 | Inherited |
| Long-chain cytokines | 0.06843 | Inherited |
| Frizzled cysteine-rich domain | 0.07213 | Inherited |
| Fibronectin type II module | 0.09773 | Inherited |
| Cadherin | 0.1128 | Inherited |
| HSP40/DnaJ peptide-binding domain | 0.1348 | Inherited |
| FAD/NAD-linked reductases, N-terminal and central domains | 0.1744 | Inherited |
| Actin/HSP70 | 0.236 | Inherited |
| PDI-like | 0.3407 | Inherited |
| Carbonic anhydrase | 0.5276 | Inherited |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0.5793 | Inherited |
| Chaperone J-domain | 0.8411 | Inherited |
| Forkhead DNA-binding domain | 0.8631 | Inherited |
| Tetratricopeptide repeat (TPR) | 0.9262 | Inherited |
LINKTO: Domain2BO Download and Domain2BO Algorithm
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Supra-domain (Single)( show details)
Highlighted in gray are those with FDR>0.001
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Duplex) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
63748,57903
63748 - Tudor/PWWP/MBT
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
57850,88697
57850 - RING/U-box
88697 - PUA domain-like | 0 | DIRECT |
54236,57889
54236 - Ubiquitin-like
57889 - Cysteine-rich domain | 0 | DIRECT |
57184,49854
57184 - Growth factor receptor domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
47576,48065
47576 - Calponin-homology domain, CH-domain
48065 - DBL homology domain (DH-domain) | 0 | DIRECT |
54236,50729
54236 - Ubiquitin-like
50729 - PH domain-like | 0 | DIRECT |
103637,103637
103637 - CCHHC domain
103637 - CCHHC domain | 0 | DIRECT |
49265,53300
49265 - Fibronectin type III
53300 - vWA-like | 0 | DIRECT |
81606,81601
81606 - PP2C-like
81601 - Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | DIRECT |
103575,48726
103575 - Plexin repeat
48726 - Immunoglobulin | 0 | DIRECT |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
49417,47719
49417 - p53-like transcription factors
47719 - p53 tetramerization domain | 0 | DIRECT |
49899,63887
49899 - Concanavalin A-like lectins/glucanases
63887 - P-domain of calnexin/calreticulin | 0 | DIRECT |
48452,57850
48452 - TPR-like
57850 - RING/U-box | 0 | DIRECT |
55550,57850
55550 - SH2 domain
57850 - RING/U-box | 0 | DIRECT |
57414,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like | 0 | DIRECT |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
56436,57535
56436 - C-type lectin-like
57535 - Complement control module/SCR domain | 0 | DIRECT |
47473,55550
47473 - EF-hand
55550 - SH2 domain | 0 | DIRECT |
53300,49899
53300 - vWA-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
82754,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins | 0 | DIRECT |
57850,48452
57850 - RING/U-box
48452 - TPR-like | 0 | DIRECT |
57184,49265
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | DIRECT |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
47986,52129
47986 - DEATH domain
52129 - Caspase-like | 0 | DIRECT |
47986,47986
47986 - DEATH domain
47986 - DEATH domain | 0 | DIRECT |
48403,47986
48403 - Ankyrin repeat
47986 - DEATH domain | 0 | DIRECT |
55753,47050
55753 - Actin depolymerizing proteins
47050 - VHP, Villin headpiece domain | 0 | DIRECT |
55753,82754
55753 - Actin depolymerizing proteins
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
64593,90257
64593 - Intermediate filament protein, coiled coil region
90257 - Myosin rod fragments | 0 | DIRECT |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
82895,57424
82895 - TSP-1 type 1 repeat
57424 - LDL receptor-like module | 0 | DIRECT |
48350,55961
48350 - GTPase activation domain, GAP
55961 - Bet v1-like | 0 | DIRECT |
48552,48552
48552 - Serum albumin-like
48552 - Serum albumin-like | 0 | DIRECT |
47668,47473
47668 - N-terminal domain of cbl (N-cbl)
47473 - EF-hand | 0 | DIRECT |
57889,49562
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
100934,100934
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
53300,49265
53300 - vWA-like
49265 - Fibronectin type III | 0 | DIRECT |
82754,82754
82754 - C-terminal, gelsolin-like domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like | 0.0000008147 | DIRECT |
69318,69179
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains | 0.0004335 | DIRECT |
69179,69179
69179 - Integrin domains
69179 - Integrin domains | 0.0004335 | DIRECT |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0.0004559 | DIRECT |
52821,52799
52821 - Rhodanese/Cell cycle control phosphatase
52799 - (Phosphotyrosine protein) phosphatases II | 0.0005123 | DIRECT |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0.001088 | INHERITED FROM: triphenylarsine |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.001185 | INHERITED FROM: Arsenites |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0.001507 | INHERITED FROM: Cacodylic Acid || dimethylarsinous acid |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0.00178 | INHERITED FROM: Arsenites |
47454,57959
47454 - A DNA-binding domain in eukaryotic transcription factors
57959 - Leucine zipper domain | 0.002752 | INHERITED FROM: Arsenites || methylarsine oxide || dimethylarsine |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.0049 | INHERITED FROM: arsenite |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0.005204 | INHERITED FROM: 4-aminophenylarsenoxide |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0.008531 | INHERITED FROM: Arsenic Trioxide |
52058,57184
52058 - L domain-like
57184 - Growth factor receptor domain | 0.01096 | INHERITED FROM: sodium arsenite |
57184,52058
57184 - Growth factor receptor domain
52058 - L domain-like | 0.01096 | INHERITED FROM: sodium arsenite |
50729,55550
50729 - PH domain-like
55550 - SH2 domain | 0.01096 | INHERITED FROM: Arsenic Trioxide |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0.01165 | INHERITED FROM: tetraarsenic tetrasulfide |
46785,144074
46785 - "Winged helix" DNA-binding domain
144074 - E2F-DP heterodimerization region | 0.02349 | INHERITED FROM: Arsenic Trioxide |
56112,47769
56112 - Protein kinase-like (PK-like)
47769 - SAM/Pointed domain | 0.02736 | INHERITED FROM: Arsenates |
57440,57440
57440 - Kringle-like
57440 - Kringle-like | 0.03218 | INHERITED FROM: Cacodylic Acid || dimethylarsinous acid || Roxarsone |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0.04318 | INHERITED FROM: darinaparsin |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0.04854 | INHERITED FROM: arsenite |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.06184 | INHERITED FROM: tetraarsenic tetrasulfide |
49785,57184
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0.1866 | INHERITED FROM: Arsenates |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0.5023 | INHERITED FROM: Arsenates |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
63748,57903
63748 - Tudor/PWWP/MBT
57903 - FYVE/PHD zinc finger | 0 | Direct |
57850,88697
57850 - RING/U-box
88697 - PUA domain-like | 0 | Direct |
54236,57889
54236 - Ubiquitin-like
57889 - Cysteine-rich domain | 0 | Direct |
57184,49854
57184 - Growth factor receptor domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
47576,48065
47576 - Calponin-homology domain, CH-domain
48065 - DBL homology domain (DH-domain) | 0 | Direct |
54236,50729
54236 - Ubiquitin-like
50729 - PH domain-like | 0 | Direct |
103637,103637
103637 - CCHHC domain
103637 - CCHHC domain | 0 | Direct |
49265,53300
49265 - Fibronectin type III
53300 - vWA-like | 0 | Direct |
81606,81601
81606 - PP2C-like
81601 - Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | Direct |
103575,48726
103575 - Plexin repeat
48726 - Immunoglobulin | 0 | Direct |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
49417,47719
49417 - p53-like transcription factors
47719 - p53 tetramerization domain | 0 | Direct |
49899,63887
49899 - Concanavalin A-like lectins/glucanases
63887 - P-domain of calnexin/calreticulin | 0 | Direct |
48452,57850
48452 - TPR-like
57850 - RING/U-box | 0 | Direct |
55550,57850
55550 - SH2 domain
57850 - RING/U-box | 0 | Direct |
57414,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like | 0 | Direct |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | Direct |
56436,57535
56436 - C-type lectin-like
57535 - Complement control module/SCR domain | 0 | Direct |
47473,55550
47473 - EF-hand
55550 - SH2 domain | 0 | Direct |
53300,49899
53300 - vWA-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
82754,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins | 0 | Direct |
57850,48452
57850 - RING/U-box
48452 - TPR-like | 0 | Direct |
57184,49265
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | Direct |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
47986,52129
47986 - DEATH domain
52129 - Caspase-like | 0 | Direct |
47986,47986
47986 - DEATH domain
47986 - DEATH domain | 0 | Direct |
48403,47986
48403 - Ankyrin repeat
47986 - DEATH domain | 0 | Direct |
55753,47050
55753 - Actin depolymerizing proteins
47050 - VHP, Villin headpiece domain | 0 | Direct |
55753,82754
55753 - Actin depolymerizing proteins
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
64593,90257
64593 - Intermediate filament protein, coiled coil region
90257 - Myosin rod fragments | 0 | Direct |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
82895,57424
82895 - TSP-1 type 1 repeat
57424 - LDL receptor-like module | 0 | Direct |
48350,55961
48350 - GTPase activation domain, GAP
55961 - Bet v1-like | 0 | Direct |
48552,48552
48552 - Serum albumin-like
48552 - Serum albumin-like | 0 | Direct |
47668,47473
47668 - N-terminal domain of cbl (N-cbl)
47473 - EF-hand | 0 | Direct |
57889,49562
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
100934,100934
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
53300,49265
53300 - vWA-like
49265 - Fibronectin type III | 0 | Direct |
82754,82754
82754 - C-terminal, gelsolin-like domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like | 0.0000008147 | Direct |
69318,69179
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains | 0.0004335 | Direct |
69179,69179
69179 - Integrin domains
69179 - Integrin domains | 0.0004335 | Direct |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0.0004559 | Direct |
52821,52799
52821 - Rhodanese/Cell cycle control phosphatase
52799 - (Phosphotyrosine protein) phosphatases II | 0.0005123 | Direct |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0.001088 | Inherited |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.001185 | Inherited |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0.001507 | Inherited |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0.00178 | Inherited |
47454,57959
47454 - A DNA-binding domain in eukaryotic transcription factors
57959 - Leucine zipper domain | 0.002752 | Inherited |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.0049 | Inherited |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0.005204 | Inherited |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0.008531 | Inherited |
52058,57184
52058 - L domain-like
57184 - Growth factor receptor domain | 0.01096 | Inherited |
57184,52058
57184 - Growth factor receptor domain
52058 - L domain-like | 0.01096 | Inherited |
50729,55550
50729 - PH domain-like
55550 - SH2 domain | 0.01096 | Inherited |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0.01165 | Inherited |
46785,144074
46785 - "Winged helix" DNA-binding domain
144074 - E2F-DP heterodimerization region | 0.02349 | Inherited |
56112,47769
56112 - Protein kinase-like (PK-like)
47769 - SAM/Pointed domain | 0.02736 | Inherited |
57440,57440
57440 - Kringle-like
57440 - Kringle-like | 0.03218 | Inherited |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0.04318 | Inherited |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0.04854 | Inherited |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.06184 | Inherited |
49785,57184
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0.1866 | Inherited |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0.5023 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Triple) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
63748,57903,57903
63748 - Tudor/PWWP/MBT
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
50044,55550,50044
50044 - SH3-domain
55550 - SH2 domain
50044 - SH3-domain | 0 | DIRECT |
82754,82754,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins | 0 | DIRECT |
47668,47473,55550
47668 - N-terminal domain of cbl (N-cbl)
47473 - EF-hand
55550 - SH2 domain | 0 | DIRECT |
47220,47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
57889,57889,49562
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
57196,57535,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
55753,55753,47050
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins
47050 - VHP, Villin headpiece domain | 0 | DIRECT |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
55550,56112,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57586,57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like
57586 - TNF receptor-like | 0 | DIRECT |
50729,55550,56112
50729 - PH domain-like
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57414,57440,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like
57440 - Kringle-like | 0 | DIRECT |
101912,103575,48726
101912 - Sema domain
103575 - Plexin repeat
48726 - Immunoglobulin | 0 | DIRECT |
55753,82754,82754
55753 - Actin depolymerizing proteins
82754 - C-terminal, gelsolin-like domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
48452,57850,88697
48452 - TPR-like
57850 - RING/U-box
88697 - PUA domain-like | 0 | DIRECT |
48552,48552,48552
48552 - Serum albumin-like
48552 - Serum albumin-like
48552 - Serum albumin-like | 0 | DIRECT |
82754,55753,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | DIRECT |
103637,103637,103637
103637 - CCHHC domain
103637 - CCHHC domain
103637 - CCHHC domain | 0 | DIRECT |
47986,47986,52129
47986 - DEATH domain
47986 - DEATH domain
52129 - Caspase-like | 0 | DIRECT |
57184,52058,57184
57184 - Growth factor receptor domain
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
49899,57196,49899
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
47473,55550,57850
47473 - EF-hand
55550 - SH2 domain
57850 - RING/U-box | 0 | DIRECT |
49265,49265,53300
49265 - Fibronectin type III
49265 - Fibronectin type III
53300 - vWA-like | 0 | DIRECT |
47576,48065,50729
47576 - Calponin-homology domain, CH-domain
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | DIRECT |
49785,57184,49265
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | DIRECT |
57850,48452,57850
57850 - RING/U-box
48452 - TPR-like
57850 - RING/U-box | 0 | DIRECT |
69179,69179,69179
69179 - Integrin domains
69179 - Integrin domains
69179 - Integrin domains | 0.0001841 | DIRECT |
69318,69179,69179
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains
69179 - Integrin domains | 0.0004335 | DIRECT |
52058,57184,52058
52058 - L domain-like
57184 - Growth factor receptor domain
52058 - L domain-like | 0.01096 | INHERITED FROM: sodium arsenite |
57196,57196,57184
57196 - EGF/Laminin
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0.02523 | INHERITED FROM: Arsenites |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0.04211 | INHERITED FROM: Arsenites |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0.06001 | INHERITED FROM: arsenite |
57440,57440,57440
57440 - Kringle-like
57440 - Kringle-like
57440 - Kringle-like | 0.0725 | INHERITED FROM: Roxarsone |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.1361 | INHERITED FROM: tetraarsenic tetrasulfide |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
63748,57903,57903
63748 - Tudor/PWWP/MBT
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0 | Direct |
50044,55550,50044
50044 - SH3-domain
55550 - SH2 domain
50044 - SH3-domain | 0 | Direct |
82754,82754,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins | 0 | Direct |
47668,47473,55550
47668 - N-terminal domain of cbl (N-cbl)
47473 - EF-hand
55550 - SH2 domain | 0 | Direct |
47220,47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | Direct |
57889,57889,49562
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
57196,57535,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
55753,55753,47050
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins
47050 - VHP, Villin headpiece domain | 0 | Direct |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
55550,56112,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57586,57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like
57586 - TNF receptor-like | 0 | Direct |
50729,55550,56112
50729 - PH domain-like
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57414,57440,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like
57440 - Kringle-like | 0 | Direct |
101912,103575,48726
101912 - Sema domain
103575 - Plexin repeat
48726 - Immunoglobulin | 0 | Direct |
55753,82754,82754
55753 - Actin depolymerizing proteins
82754 - C-terminal, gelsolin-like domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
48452,57850,88697
48452 - TPR-like
57850 - RING/U-box
88697 - PUA domain-like | 0 | Direct |
48552,48552,48552
48552 - Serum albumin-like
48552 - Serum albumin-like
48552 - Serum albumin-like | 0 | Direct |
82754,55753,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | Direct |
103637,103637,103637
103637 - CCHHC domain
103637 - CCHHC domain
103637 - CCHHC domain | 0 | Direct |
47986,47986,52129
47986 - DEATH domain
47986 - DEATH domain
52129 - Caspase-like | 0 | Direct |
57184,52058,57184
57184 - Growth factor receptor domain
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | Direct |
49899,57196,49899
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
47473,55550,57850
47473 - EF-hand
55550 - SH2 domain
57850 - RING/U-box | 0 | Direct |
49265,49265,53300
49265 - Fibronectin type III
49265 - Fibronectin type III
53300 - vWA-like | 0 | Direct |
47576,48065,50729
47576 - Calponin-homology domain, CH-domain
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | Direct |
49785,57184,49265
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | Direct |
57850,48452,57850
57850 - RING/U-box
48452 - TPR-like
57850 - RING/U-box | 0 | Direct |
69179,69179,69179
69179 - Integrin domains
69179 - Integrin domains
69179 - Integrin domains | 0.0001841 | Direct |
69318,69179,69179
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains
69179 - Integrin domains | 0.0004335 | Direct |
52058,57184,52058
52058 - L domain-like
57184 - Growth factor receptor domain
52058 - L domain-like | 0.01096 | Inherited |
57196,57196,57184
57196 - EGF/Laminin
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0.02523 | Inherited |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0.04211 | Inherited |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0.06001 | Inherited |
57440,57440,57440
57440 - Kringle-like
57440 - Kringle-like
57440 - Kringle-like | 0.0725 | Inherited |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.1361 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Plot distribution on species Tree Of Life (sTOL) for Superfamily and/or Family domains annotated by this CC term
 |
Plot tree as:
| |
Download Newick format tree:
|
( show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domain
architecture data for all genomes in SUPERFAMILY. The PAUP
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
Plot distribution on species Tree Of Life (sTOL) for single supra-domains annotated by this CC term
|
Plot tree as:
| |
Download Newick format tree:
| |
Browsing in TREE OF LIFE:
|
( show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
|
|
> BO Hierarchy > Arsenicals
