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CTD Chemicals (CC): Bacterial Toxins  
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Biomedical Ontology
Like Gene Ontology (GO), biomedical ontology such as phenotype ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Biomedical ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI’s thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology Based on YP which is the major contributor to the ‘Ascomycete phenotype ontology’, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- UniProtKB KeyWords (KW) Ontology Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- CTD Diseases (CD) Ontology CD is MEDIC disease vocabulary that is modified by CTD from the "Diseases" [C] branch of Medical Subject Headings (MeSH), combined with genetic disorders from the Online Mendelian Inheritance in OMIM database.
- CTD Chemicals (CC) Ontology CC is chemical vocabulary that is adapted by CTD from the "Chemicals and Drugs" category and Supplementary Concept Records of Medical Subject Headings (MeSH, a hierarchical vocabulary used to index articles for MEDLINE/PubMed).
Jump to [ Top · Hierarchy · Annotations ]
Root: CC Hierarchy (CTD chemicals from Comparative Toxicogenomics Database)
| Shortest distance to current term (+ for parents, - for children) |
CC term [CC ID] <#Children> |
#Domains (Superfamily|Family) |
#Supra-domain (Single|Duplex|Triple) |
| + + + 3: | Chemicals [MESH:D] <13> |
| + + 2: | Biological Factors [MESH:D001685] <39> | (253|342) |
(261|248|150) |
| + 1: | Toxins, Biological [MESH:D014118] <28> | (140|196) |
(143|145|87) |
| 0: | Bacterial Toxins [MESH:D001427] <180> | (42|48) |
(44|24|8) |
| - 1: | Diphtheria Toxin [MESH:D004167] <27> | (0|0) |
(0|0|0) |
| - 1: | Cholera Toxin [MESH:D002772] <17> | (0|0) |
(0|0|0) |
| - 1: | Endotoxins [MESH:D004731] <17> | (26|33) |
(28|13|7) |
| - 1: | Botulinum Toxins [MESH:D001905] <14> | (8|8) |
(9|8|1) |
| - 1: | Virulence Factors, Bordetella [MESH:D010566] <12> | (0|1) |
(1|0|0) |
| - 1: | Cord Factors [MESH:D003311] <11> | (0|0) |
(0|0|0) |
| - 1: | Tetanus Toxin [MESH:D013744] <8> | (0|0) |
(0|0|0) |
| - 1: | Shiga Toxins [MESH:D022603] <4> | (1|1) |
(1|0|0) |
| - 1: | Streptolysins [MESH:D013301] <4> | (0|0) |
(0|0|0) |
| - 1: | 16S toxin, Clostridium botulinum [MESH:C116382] | (0|0) |
(0|0|0) |
| - 1: | 4-hydroxyhomoanatoxin-a [MESH:C482099] | (0|0) |
(0|0|0) |
| - 1: | AapA1 protein, Helicobacter pylori [MESH:C000622449] | (0|0) |
(0|0|0) |
| - 1: | BLF1 toxin, Burkholderia pseudomallei [MESH:C572779] | (0|0) |
(0|0|0) |
| - 1: | BMS-191352 protein, recombinant [MESH:C115038] | (0|0) |
(0|0|0) |
| - 1: | BPSL1549 protein, Burkholderia pseudomallei [MESH:C568181] | (0|0) |
(0|0|0) |
| - 1: | Bacillus thuringiensis ovicidal toxin [MESH:C049673] | (0|0) |
(0|0|0) |
| - 1: | Bacillus thuringiensis protoxin [MESH:C029103] | (0|0) |
(0|0|0) |
| - 1: | Bacteroides fragilis toxin [MESH:C405031] | (0|0) |
(0|0|0) |
| - 1: | CARDS toxin, Mycoplasma pneumoniae [MESH:C546120] | (0|0) |
(0|0|0) |
| - 1: | CDI toxin, Yersinia kristensenii [MESH:C000622114] | (0|0) |
(0|0|0) |
| - 1: | CNF3 protein, E coli [MESH:C000629604] | (0|0) |
(0|0|0) |
| - 1: | CPB protein, Clostridium perfringens [MESH:C031884] | (0|0) |
(0|0|0) |
| - 1: | CRY11BB protein, Bacillus thuringiensis [MESH:C115468] | (0|0) |
(0|0|0) |
| - 1: | CRY18AA protein, Paenibacillus popilliae [MESH:C107108] | (0|0) |
(0|0|0) |
| - 1: | CRY1BD protein, Bacillus thuringiensis [MESH:C406926] | (0|0) |
(0|0|0) |
| - 1: | CRY1GB protein, Bacillus thuringiensis [MESH:C406925] | (0|0) |
(0|0|0) |
| - 1: | CRY20AA protein, Bacillus thuringiensis [MESH:C110173] | (0|0) |
(0|0|0) |
| - 1: | Cbm17.1 protein, Clostridium bifermentans [MESH:C112995] | (0|0) |
(0|0|0) |
| - 1: | Cbm17.2 protein, Clostridium bifermentans [MESH:C112996] | (0|0) |
(0|0|0) |
| - 1: | Cbm72 protein, Clostridium bifermentans [MESH:C112994] | (0|0) |
(0|0|0) |
| - 1: | CdtA protein, Haemophilus ducreyi [MESH:C468508] | (0|0) |
(0|0|0) |
| - 1: | CdtB protein, Salmonella typhimurium [MESH:C000589672] | (0|0) |
(0|0|0) |
| - 1: | CdtC protein, Haemophilus ducreyi [MESH:C468509] | (0|0) |
(0|0|0) |
| - 1: | ChpAK protein, E coli [MESH:C465568] | (0|0) |
(0|0|0) |
| - 1: | ChpK protein, bacteria [MESH:C439055] | (0|0) |
(0|0|0) |
| - 1: | Clostridium difficile lethal toxin B [MESH:C488583] | (0|0) |
(0|0|0) |
| - 1: | Clostridium novyi alpha-toxin [MESH:C075216] | (0|0) |
(0|0|0) |
| - 1: | Clostridium perfringens delta-toxin [MESH:C029352] | (0|0) |
(0|0|0) |
| - 1: | Clostridium perfringens epsilon-toxin [MESH:C039811] | (0|0) |
(0|0|0) |
| - 1: | Clostridium perfringens theta-toxin [MESH:C020452] | (0|0) |
(0|0|0) |
| - 1: | Cry41Aa protein, Bacillus thuringiensis [MESH:C000620821] | (0|0) |
(0|0|0) |
| - 1: | EHEC-hlyA protein, E coli [MESH:C097321] | (0|0) |
(0|0|0) |
| - 1: | Efa1 protein, E coli [MESH:C404907] | (0|0) |
(0|0|0) |
| - 1: | Exfoliatins [MESH:D005083] | (0|0) |
(0|0|0) |
| - 1: | EzeT protein, E coli [MESH:C000606986] | (0|0) |
(0|0|0) |
| - 1: | Fst-like toxin, Streptococcus mutans [MESH:C582269] | (0|0) |
(0|0|0) |
| - 1: | Gly1 protein, Neisseria gonorrhoeae [MESH:C117489] | (0|0) |
(0|0|0) |
| - 1: | HEC toxin, Aeromonas hydrophila [MESH:C475608] | (0|0) |
(0|0|0) |
| - 1: | HS-6, Nocardia [MESH:C078066] | (0|0) |
(0|0|0) |
| - 1: | Hlg2 protein, Staphylococcus [MESH:C503458] | (0|0) |
(0|0|0) |
| - 1: | Hok protein, E coli [MESH:C087025] | (0|0) |
(0|0|0) |
| - 1: | HokB protein, E coli [MESH:C000601825] | (0|0) |
(0|0|0) |
| - 1: | HokC protein, E coli [MESH:C071524] | (0|0) |
(0|0|0) |
| - 1: | IbsC protein, E coli [MESH:C555654] | (0|0) |
(0|0|0) |
| - 1: | K99 antigen [MESH:C031429] | (0|0) |
(0|0|0) |
| - 1: | Kid protein, Bacteria [MESH:C068353] | (0|0) |
(0|0|0) |
| - 1: | LMB-11 [MESH:C000625804] | (0|0) |
(0|0|0) |
| - 1: | LdrD protein, E coli [MESH:C465558] | (0|0) |
(0|0|0) |
| - 1: | LktD protein, Actinobacillus actinomycetemcomitans [MESH:C096841] | (0|0) |
(0|0|0) |
| - 1: | LngA protein, E coli [MESH:C121921] | (0|0) |
(0|0|0) |
| - 1: | LsoA protein, E coli [MESH:C572392] | (0|0) |
(0|0|0) |
| - 1: | MazE4 protein, Mycobacterium tuberculosis [MESH:C000628727] | (0|0) |
(0|0|0) |
| - 1: | McyH protein, Microcystis aeruginosa [MESH:C496657] | (0|0) |
(0|0|0) |
| - 1: | Mtx2 protein, Bacillus sphaericus [MESH:C099210] | (0|0) |
(0|0|0) |
| - 1: | NE B-like toxin, Clostridium perfringens [MESH:C572202] | (0|0) |
(0|0|0) |
| - 1: | NetB protein, Clostridium perfringens [MESH:C534774] | (0|0) |
(0|0|0) |
| - 1: | NheA protein, Bacillus cereus [MESH:C000589183] | (0|0) |
(0|0|0) |
| - 1: | OrtT protein, E coli [MESH:C000602129] | (0|0) |
(0|0|0) |
| - 1: | PRX302 [MESH:C518473] | (0|0) |
(0|0|0) |
| - 1: | Panton-Valentine leukocidin [MESH:C078284] | (0|0) |
(0|0|0) |
| - 1: | ParE2 protein, E coli [MESH:C000610596] | (0|0) |
(0|0|0) |
| - 1: | PasB protein, Thiobacillus ferrooxidans [MESH:C110605] | (0|0) |
(0|0|0) |
| - 1: | Pasteurella multocida toxin [MESH:C062258] | (0|0) |
(0|0|0) |
| - 1: | PaxA protein, Pasteurella aerogenes [MESH:C402669] | (0|0) |
(0|0|0) |
| - 1: | Pet protein, E coli [MESH:C530786] | (0|0) |
(0|0|0) |
| - 1: | PltA protein, Salmonella typhimurium [MESH:C000589652] | (0|0) |
(0|0|0) |
| - 1: | PltB protein, Salmonella typhimurium [MESH:C000589671] | (0|0) |
(0|0|0) |
| - 1: | Pseudomonas aeruginosa O polysaccharide-toxin A conjugate vaccine [MESH:C060069] | (0|0) |
(0|0|0) |
| - 1: | PtlC protein, Bordetella pertussis [MESH:C117492] | (0|0) |
(0|0|0) |
| - 1: | Pyolysin, Arcanobacterium pyogenes [MESH:C108448] | (0|0) |
(0|0|0) |
| - 1: | RatA protein, E coli [MESH:C558779] | (0|0) |
(0|0|0) |
| - 1: | RelE protein, E coli [MESH:C465566] | (0|0) |
(0|0|0) |
| - 1: | RtxA protein, Vibrio cholerae [MESH:C434464] | (0|0) |
(0|0|0) |
| - 1: | Rv0595c protein, Mycobacterium tuberculosis [MESH:C000606753] | (0|0) |
(0|0|0) |
| - 1: | Rv3903 protein, Mycobacterium tuberculosis [MESH:C000589201] | (0|0) |
(0|0|0) |
| - 1: | SepB protein, Serratia entomophila [MESH:C413456] | (0|0) |
(0|0|0) |
| - 1: | SepC protein, Serratia entomophila [MESH:C413457] | (0|0) |
(0|0|0) |
| - 1: | SrnB protein, E coli [MESH:C087024] | (0|0) |
(0|0|0) |
| - 1: | Staphylococcal pyrogenic exotoxin C [MESH:C034933] | (0|0) |
(0|0|0) |
| - 1: | Tf-CRM107 [MESH:C404391] | (0|0) |
(0|0|0) |
| - 1: | TisB toxin, E coli [MESH:C575529] | (0|0) |
(0|0|0) |
| - 1: | VIP2 protein, Bacillus cereus [MESH:C121896] | (0|0) |
(0|0|0) |
| - 1: | VapC protein, Mycobacterium smegmatis [MESH:C000592554] | (0|0) |
(0|0|0) |
| - 1: | VapC protein, Streptomyces [MESH:C000624524] | (0|0) |
(0|0|0) |
| - 1: | VapC20 protein, Mycobacterium tuberculosis [MESH:C000625649] | (0|0) |
(0|0|0) |
| - 1: | Vibrio cholerae WO7 toxin [MESH:C420689] | (0|0) |
(0|0|0) |
| - 1: | XptA1 protein, Xenorhabdus nematophilus [MESH:C433925] | (0|0) |
(0|0|0) |
| - 1: | YafO protein, E coli [MESH:C544331] | (0|0) |
(0|0|0) |
| - 1: | YafQ protein, E coli [MESH:C523350] | (0|0) |
(0|0|0) |
| - 1: | YeeV protein, E coli [MESH:C557198] | (0|0) |
(0|0|0) |
| - 1: | YjhX protein, E coli [MESH:C000606973] | (0|0) |
(0|0|0) |
| - 1: | YjjJ protein, E coli [MESH:C000625837] | (0|0) |
(0|0|0) |
| - 1: | YoeB protein, E coli [MESH:C504245] | (0|0) |
(0|0|0) |
| - 1: | YoeB(Sa1) protein, Staphylococcus aureus [MESH:C587017] | (0|0) |
(0|0|0) |
| - 1: | ZorO protein, E coli [MESH:C587788] | (0|0) |
(0|0|0) |
| - 1: | aerolysin [MESH:C032676] | (0|0) |
(0|0|0) |
| - 1: | alpha toxin, Clostridium perfringens [MESH:C040649] | (0|0) |
(0|0|0) |
| - 1: | alpha-xenorhabdolysin, Xenorhabdus nematophila [MESH:C519450] | (0|0) |
(0|0|0) |
| - 1: | amylosin, Bacillus [MESH:C545909] | (0|0) |
(0|0|0) |
| - 1: | angubindin-1 [MESH:C000654183] | (0|0) |
(0|0|0) |
| - 1: | anthrax toxin [MESH:C030325] | (0|0) |
(0|0|0) |
| - 1: | antigen V, Pseudomonas [MESH:C118546] | (0|0) |
(0|0|0) |
| - 1: | aphantoxin [MESH:C034321] | (0|0) |
(0|0|0) |
| - 1: | binB protein, Bacillus sphaericus [MESH:C046134] | (0|0) |
(0|0|0) |
| - 1: | cell-elongating factor, Vibrio cholerae [MESH:C412287] | (0|0) |
(0|0|0) |
| - 1: | cholix toxin, Vibrio cholerae [MESH:C529269] | (2|2) |
(2|0|0) |
| - 1: | cpb2 protein, Clostridium perfringens [MESH:C109896] | (0|0) |
(0|0|0) |
| - 1: | cyanobacterial toxin [MESH:C014986] | (0|0) |
(0|0|0) |
| - 1: | cylindrospermopsin [MESH:C089595] | (6|4) |
(6|1|0) |
| - 1: | cytolethal distending toxin [MESH:C067044] | (0|0) |
(0|0|0) |
| - 1: | cytolethal distending toxin, Actinobacillus actinomycetemcomitans [MESH:C447141] | (0|0) |
(0|0|0) |
| - 1: | cytotoxic necrotizing factor type 1 [MESH:C060296] | (0|0) |
(0|0|0) |
| - 1: | cytotoxic necrotizing factor type 2 [MESH:C086995] | (0|0) |
(0|0|0) |
| - 1: | dermonecrotic toxin, Pasteurella multocida [MESH:C052804] | (0|0) |
(0|0|0) |
| - 1: | enterotoxin F, Staphylococcal [MESH:C030107] | (1|0) |
(1|0|0) |
| - 1: | enterotoxin, Vibrio hollisae [MESH:C051555] | (0|0) |
(0|0|0) |
| - 1: | exoenzyme S [MESH:C444820] | (0|0) |
(0|0|0) |
| - 1: | fst toxin, Enterococcus faecalis [MESH:C473319] | (0|0) |
(0|0|0) |
| - 1: | gamma-hemolysin, Staphylococcus aureus [MESH:C037956] | (0|0) |
(0|0|0) |
| - 1: | heat stable toxin (E coli) [MESH:C034151] | (0|0) |
(0|0|0) |
| - 1: | heat-labile enterotoxin, E coli [MESH:C027538] | (0|0) |
(0|0|0) |
| - 1: | heat-stable enterotoxin (Yersinia) [MESH:C048669] | (0|0) |
(0|0|0) |
| - 1: | hemolytic toxin, Clostridium septicum [MESH:C064270] | (0|0) |
(0|0|0) |
| - 1: | hemorrhagic toxin HT, Clostridium sordellii [MESH:C072293] | (0|0) |
(0|0|0) |
| - 1: | hemorrhagic toxin, Clostridium sporogenes [MESH:C101983] | (0|0) |
(0|0|0) |
| - 1: | hlb protein, Staphylococcus aureus [MESH:C029878] | (0|0) |
(0|0|0) |
| - 1: | hlyA protein, Listeria monocytogenes [MESH:C038705] | (0|0) |
(0|0|0) |
| - 1: | homoanatoxin-a [MESH:C524097] | (0|0) |
(0|0|0) |
| - 1: | immunotoxin 4D5MOCB-ETA [MESH:C483831] | (0|0) |
(0|0|0) |
| - 1: | immunotoxin HA22 [MESH:C541974] | (0|0) |
(0|0|0) |
| - 1: | interleukin-4-Pseudomonas exotoxin [MESH:C479467] | (0|0) |
(0|0|0) |
| - 1: | iota toxin, Clostridium perfringens [MESH:C050737] | (0|0) |
(0|0|0) |
| - 1: | iota toxin, Clostridium spiroforme [MESH:C054948] | (0|0) |
(0|0|0) |
| - 1: | larval toxin, Bacillus [MESH:C045759] | (0|0) |
(0|0|0) |
| - 1: | lethal toxin LT, Clostridium sordellii [MESH:C072292] | (0|0) |
(0|0|0) |
| - 1: | lymphostatin protein, E coli [MESH:C406587] | (0|0) |
(0|0|0) |
| - 1: | mangotoxin, Pseudomonas syringae [MESH:C574905] | (0|0) |
(0|0|0) |
| - 1: | mitilysin, Streptococcus mitis [MESH:C517494] | (0|0) |
(0|0|0) |
| - 1: | mitogenic exotoxin Z protein, Streptococcus [MESH:C107894] | (0|0) |
(0|0|0) |
| - 1: | mosquitocidal toxin SSII-1 [MESH:C068603] | (0|0) |
(0|0|0) |
| - 1: | p29 crystal protein, Bacillus thuringiensis [MESH:C507669] | (0|0) |
(0|0|0) |
| - 1: | parasporin-2Ab protein, Bacillus thuringiensis [MESH:C525212] | (0|0) |
(0|0|0) |
| - 1: | pinnamine [MESH:C503218] | (0|0) |
(0|0|0) |
| - 1: | pndA protein, E coli [MESH:C087023] | (0|0) |
(0|0|0) |
| - 1: | prlF protein, E coli [MESH:C524841] | (0|0) |
(0|0|0) |
| - 1: | proaerolysin [MESH:C107096] | (0|0) |
(0|0|0) |
| - 1: | putative killer toxin-like protein, Streptomyces sp. [MESH:C121318] | (0|0) |
(0|0|0) |
| - 1: | secreted autotransporter toxin, E coli [MESH:C506813] | (0|0) |
(0|0|0) |
| - 1: | seeligeriolysin O, Listeria seeligeri [MESH:C510990] | (0|0) |
(0|0|0) |
| - 1: | senA protein, E coli [MESH:C096906] | (0|0) |
(0|0|0) |
| - 1: | sepA protein, Serratia entomophila [MESH:C413455] | (0|0) |
(0|0|0) |
| - 1: | staphylococcal alpha-toxin [MESH:C021091] | (0|0) |
(0|0|0) |
| - 1: | staphylococcal delta toxin [MESH:C025971] | (0|0) |
(0|0|0) |
| - 1: | staphylococcal pyrogenic exotoxin type B [MESH:C091239] | (0|0) |
(0|0|0) |
| - 1: | staphylotoxin [MESH:C036117] | (0|0) |
(0|0|0) |
| - 1: | tcdA protein, Clostridium difficile [MESH:C041348] | (1|1) |
(1|0|0) |
| - 1: | thermostable direct hemolysin [MESH:C068489] | (0|0) |
(0|0|0) |
| - 1: | tosA protein, E coli [MESH:C561978] | (0|0) |
(0|0|0) |
| - 1: | toxA protein, Pseudomonas aeruginosa [MESH:C012519] | (0|0) |
(0|0|0) |
| - 1: | toxB protein, Clostridium difficile [MESH:C031815] | (0|0) |
(0|0|0) |
| - 1: | toxin 1593 (Bacillus sphaericus) [MESH:C057949] | (0|0) |
(0|0|0) |
| - 1: | toxin A (Pseudomonas) [MESH:C029294] | (0|0) |
(0|0|0) |
| - 1: | toxin A, Photorhabdus [MESH:C118454] | (0|0) |
(0|0|0) |
| - 1: | toxin B, Photorhabdus [MESH:C118455] | (0|0) |
(0|0|0) |
| - 1: | toxin L, Clostridium sordellii [MESH:C073548] | (0|0) |
(0|0|0) |
| - 1: | toxin R, Clostridium difficile [MESH:C549683] | (0|0) |
(0|0|0) |
| - 1: | toxin-LR [MESH:C038174] | (0|0) |
(0|0|0) |
| - 1: | vacuolating autotransporter toxin, E coli [MESH:C000605763] | (0|0) |
(0|0|0) |
| - 1: | vaginolysin, Gardnerella vaginalis [MESH:C542392] | (0|0) |
(0|0|0) |
| - 1: | yhaV protein, E coli [MESH:C524842] | (0|0) |
(0|0|0) |
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Superfamily( show details)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| Interleukin 8-like chemokines | 0 | DIRECT |
| Nitric oxide (NO) synthase oxygenase domain | 0 | DIRECT |
| Indolic compounds 2,3-dioxygenase-like | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| Toll/Interleukin receptor TIR domain | 0.000000001768 | DIRECT |
| 4-helical cytokines | 0.00000001195 | DIRECT |
| DEATH domain | 0.00000003167 | DIRECT |
| Histone-fold | 0.0000002019 | DIRECT |
| STAT | 0.000002816 | DIRECT |
| Transcription factor STAT-4 N-domain | 0.000002816 | DIRECT |
| Caspase-like | 0.000003692 | DIRECT |
| TNF-like | 0.0001081 | DIRECT |
| Cystine-knot cytokines | 0.0001123 | DIRECT |
| SCOP hierarchy in SUPERFAMILY | 0.0005237 | DIRECT |
| Cytochrome P450 | 0.001438 | INHERITED FROM: cylindrospermopsin |
| Class II aaRS and biotin synthetases | 0.001624 | INHERITED FROM: Lipopolysaccharides |
| Cytokine | 0.00211 | INHERITED FROM: Lipopolysaccharides || Endotoxins |
| PGBD-like | 0.004024 | INHERITED FROM: Lipopolysaccharides || Endotoxins |
| TIMP-like | 0.005073 | INHERITED FROM: lipopolysaccharide, E. coli O26-B6 |
| p53-like transcription factors | 0.005445 | INHERITED FROM: Lipopolysaccharides || Endotoxins |
| 4Fe-4S ferredoxins | 0.006235 | INHERITED FROM: Lipopolysaccharides || Endotoxins |
| Leucine zipper domain | 0.006851 | INHERITED FROM: cylindrospermopsin |
| TNF receptor-like | 0.01046 | INHERITED FROM: Lipopolysaccharides |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.01105 | INHERITED FROM: Lipopolysaccharides || Endotoxins |
| Riboflavin synthase domain-like | 0.01105 | INHERITED FROM: Lipopolysaccharides || Endotoxins |
| post-AAA+ oligomerization domain-like | 0.01133 | INHERITED FROM: Botulinum Toxins || Botulinum Toxins, Type A || incobotulinumtoxinA |
| alpha/beta knot | 0.01133 | INHERITED FROM: cylindrospermopsin |
| Somatomedin B domain | 0.01459 | INHERITED FROM: Botulinum Toxins || Botulinum Toxins, Type A || incobotulinumtoxinA |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.01505 | INHERITED FROM: Endotoxins |
| Hemopexin-like domain | 0.01556 | INHERITED FROM: Lipopolysaccharides |
| Flavoproteins | 0.01781 | INHERITED FROM: Lipopolysaccharides || Endotoxins |
| Troponin coil-coiled subunits | 0.02135 | INHERITED FROM: Botulinum Toxins || Botulinum Toxins, Type A || incobotulinumtoxinA |
| DNA clamp | 0.02135 | INHERITED FROM: cylindrospermopsin |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.02517 | INHERITED FROM: cylindrospermopsin |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0.02882 | INHERITED FROM: Endotoxins |
| Tropomyosin | 0.03553 | INHERITED FROM: Botulinum Toxins, Type A || incobotulinumtoxinA |
| Fibronectin type III | 0.05812 | INHERITED FROM: Botulinum Toxins, Type A || incobotulinumtoxinA |
| L30e-like | 0.07537 | INHERITED FROM: cylindrospermopsin |
| Protein kinase-like (PK-like) | 0.1944 | INHERITED FROM: cholix toxin, Vibrio cholerae |
| Growth factor receptor domain | 0.3255 | INHERITED FROM: Botulinum Toxins || incobotulinumtoxinA |
| P-loop containing nucleoside triphosphate hydrolases | 0.5628 | INHERITED FROM: Botulinum Toxins || incobotulinumtoxinA |
LINKTO: Domain2BO Download and Domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Family( show details)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| Interleukin 8-like chemokines | 0 | DIRECT |
| Ribonuclease H | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | DIRECT |
| Nitric oxide (NO) synthase oxygenase domain | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| Nucleosome core histones | 0.0000000002847 | DIRECT |
| Toll/Interleukin receptor TIR domain | 0.00000001128 | DIRECT |
| Interleukin-1 (IL-1) | 0.0000004546 | DIRECT |
| Short-chain cytokines | 0.0000008307 | DIRECT |
| STAT | 0.000002897 | DIRECT |
| Transcription factor STAT-4 N-domain | 0.000002897 | DIRECT |
| STAT DNA-binding domain | 0.000002897 | DIRECT |
| Caspase catalytic domain | 0.000003894 | DIRECT |
| TNF-like | 0.00009525 | DIRECT |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0.0008344 | DIRECT |
| Glutathione peroxidase-like | 0.0008344 | DIRECT |
| Transforming growth factor (TGF)-beta | 0.0009645 | DIRECT |
| Rel/Dorsal transcription factors, DNA-binding domain | 0.001189 | INHERITED FROM: Lipopolysaccharides || lipopolysaccharide, E. coli O26-B6 || Endotoxins |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0.001457 | INHERITED FROM: Botulinum Toxins || Botulinum Toxins, Type A || incobotulinumtoxinA |
| NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0.003013 | INHERITED FROM: Lipopolysaccharides || lipopolysaccharide, E. coli O26-B6 || Endotoxins |
| Cytochrome P450 | 0.00423 | INHERITED FROM: cylindrospermopsin |
| MMP N-terminal domain | 0.004531 | INHERITED FROM: Lipopolysaccharides || Endotoxins |
| NADPH-cytochrome p450 reductase FAD-binding domain-like | 0.005761 | INHERITED FROM: Lipopolysaccharides || Endotoxins |
| NADPH-cytochrome p450 reductase-like | 0.005761 | INHERITED FROM: Lipopolysaccharides || Endotoxins |
| DEATH effector domain, DED | 0.006052 | INHERITED FROM: Lipopolysaccharides || Endotoxins |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0.006052 | INHERITED FROM: Botulinum Toxins || Botulinum Toxins, Type A || incobotulinumtoxinA |
| Tissue inhibitor of metalloproteinases, TIMP | 0.006052 | INHERITED FROM: Lipopolysaccharides || lipopolysaccharide, E. coli O26-B6 || Endotoxins |
| TNF receptor-like | 0.007522 | INHERITED FROM: Lipopolysaccharides |
| Leucine zipper domain | 0.008917 | INHERITED FROM: cylindrospermopsin |
| Long-chain cytokines | 0.01076 | INHERITED FROM: Lipopolysaccharides || Virulence Factors, Bordetella || Endotoxins |
| Caspase recruitment domain, CARD | 0.01174 | INHERITED FROM: Lipopolysaccharides |
| Matrix metalloproteases, catalytic domain | 0.01174 | INHERITED FROM: Lipopolysaccharides || Endotoxins |
| Somatomedin B domain | 0.01482 | INHERITED FROM: Botulinum Toxins || Botulinum Toxins, Type A || incobotulinumtoxinA |
| Cytochrome p450 reductase N-terminal domain-like | 0.01482 | INHERITED FROM: Lipopolysaccharides || Endotoxins |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.01567 | INHERITED FROM: Endotoxins |
| Hemopexin-like domain | 0.01747 | INHERITED FROM: Lipopolysaccharides |
| DEATH domain, DD | 0.01914 | INHERITED FROM: Lipopolysaccharides || lipopolysaccharide, E. coli O26-B6 |
| Interleukin 17F, IL-17F | 0.02113 | INHERITED FROM: Lipopolysaccharides || Endotoxins |
| Interferon regulatory factor | 0.02936 | INHERITED FROM: Lipopolysaccharides || Endotoxins |
| Tropomyosin | 0.03891 | INHERITED FROM: Botulinum Toxins, Type A || incobotulinumtoxinA |
| UDPGT-like | 0.04375 | INHERITED FROM: cylindrospermopsin |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.0603 | INHERITED FROM: Lipopolysaccharides || Endotoxins |
| C2 set domains | 0.07927 | INHERITED FROM: lipopolysaccharide, E coli O55-B5 |
| Motor proteins | 0.08812 | INHERITED FROM: Botulinum Toxins || Botulinum Toxins, Type A || incobotulinumtoxinA |
| Protein kinases, catalytic subunit | 0.1907 | INHERITED FROM: cholix toxin, Vibrio cholerae |
| Extended AAA-ATPase domain | 0.2207 | INHERITED FROM: incobotulinumtoxinA |
| Dual specificity phosphatase-like | 0.4362 | INHERITED FROM: cylindrospermopsin |
| G proteins | 1 | INHERITED FROM: exoenzyme C3, Clostridium botulinum |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| Interleukin 8-like chemokines | 0 | Direct |
| Ribonuclease H | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | Direct |
| Nitric oxide (NO) synthase oxygenase domain | 0 | Direct |
| Ribosomal protein S18 | 0 | Direct |
| Nucleosome core histones | 0.0000000002847 | Direct |
| Toll/Interleukin receptor TIR domain | 0.00000001128 | Direct |
| Interleukin-1 (IL-1) | 0.0000004546 | Direct |
| Short-chain cytokines | 0.0000008307 | Direct |
| STAT | 0.000002897 | Direct |
| Transcription factor STAT-4 N-domain | 0.000002897 | Direct |
| STAT DNA-binding domain | 0.000002897 | Direct |
| Caspase catalytic domain | 0.000003894 | Direct |
| TNF-like | 0.00009525 | Direct |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0.0008344 | Direct |
| Glutathione peroxidase-like | 0.0008344 | Direct |
| Transforming growth factor (TGF)-beta | 0.0009645 | Direct |
| Rel/Dorsal transcription factors, DNA-binding domain | 0.001189 | Inherited |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0.001457 | Inherited |
| NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0.003013 | Inherited |
| Cytochrome P450 | 0.00423 | Inherited |
| MMP N-terminal domain | 0.004531 | Inherited |
| NADPH-cytochrome p450 reductase FAD-binding domain-like | 0.005761 | Inherited |
| NADPH-cytochrome p450 reductase-like | 0.005761 | Inherited |
| DEATH effector domain, DED | 0.006052 | Inherited |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0.006052 | Inherited |
| Tissue inhibitor of metalloproteinases, TIMP | 0.006052 | Inherited |
| TNF receptor-like | 0.007522 | Inherited |
| Leucine zipper domain | 0.008917 | Inherited |
| Long-chain cytokines | 0.01076 | Inherited |
| Caspase recruitment domain, CARD | 0.01174 | Inherited |
| Matrix metalloproteases, catalytic domain | 0.01174 | Inherited |
| Somatomedin B domain | 0.01482 | Inherited |
| Cytochrome p450 reductase N-terminal domain-like | 0.01482 | Inherited |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.01567 | Inherited |
| Hemopexin-like domain | 0.01747 | Inherited |
| DEATH domain, DD | 0.01914 | Inherited |
| Interleukin 17F, IL-17F | 0.02113 | Inherited |
| Interferon regulatory factor | 0.02936 | Inherited |
| Tropomyosin | 0.03891 | Inherited |
| UDPGT-like | 0.04375 | Inherited |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.0603 | Inherited |
| C2 set domains | 0.07927 | Inherited |
| Motor proteins | 0.08812 | Inherited |
| Protein kinases, catalytic subunit | 0.1907 | Inherited |
| Extended AAA-ATPase domain | 0.2207 | Inherited |
| Dual specificity phosphatase-like | 0.4362 | Inherited |
| G proteins | 1 | Inherited |
LINKTO: Domain2BO Download and Domain2BO Algorithm
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Supra-domain (Single)( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Nitric oxide (NO) synthase oxygenase domain | 0 | DIRECT |
| Interleukin 8-like chemokines | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| Indolic compounds 2,3-dioxygenase-like | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | DIRECT |
| Toll/Interleukin receptor TIR domain | 0.0000000007277 | DIRECT |
| 4-helical cytokines | 0.000000005039 | DIRECT |
| DEATH domain | 0.00000001359 | DIRECT |
| Histone-fold | 0.0000000895 | DIRECT |
| STAT | 0.000001333 | DIRECT |
| Transcription factor STAT-4 N-domain | 0.000001333 | DIRECT |
| Caspase-like | 0.00000176 | DIRECT |
| TNF-like | 0.00005815 | DIRECT |
| Cystine-knot cytokines | 0.00006048 | DIRECT |
| Polo-box domain | 0.0008219 | DIRECT |
| Cytochrome P450 | 0.0008748 | DIRECT |
| Class II aaRS and biotin synthetases | 0.000995 | DIRECT |
| Bcl-2 inhibitors of programmed cell death | 0.001131 | INHERITED FROM: Lipopolysaccharides |
| Cytokine | 0.001309 | INHERITED FROM: Endotoxins || Lipopolysaccharides |
| PGBD-like | 0.00258 | INHERITED FROM: Endotoxins || Lipopolysaccharides |
| TIMP-like | 0.003286 | INHERITED FROM: lipopolysaccharide, E. coli O26-B6 |
| p53-like transcription factors | 0.003543 | INHERITED FROM: Endotoxins || Lipopolysaccharides |
| 4Fe-4S ferredoxins | 0.004091 | INHERITED FROM: Endotoxins || Lipopolysaccharides |
| Leucine zipper domain | 0.00452 | INHERITED FROM: cylindrospermopsin || Lipopolysaccharides |
| TNF receptor-like | 0.007069 | INHERITED FROM: lipopolysaccharide, E. coli O26-B6 || Lipopolysaccharides |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.007493 | INHERITED FROM: Endotoxins || Lipopolysaccharides |
| Riboflavin synthase domain-like | 0.007493 | INHERITED FROM: Endotoxins || Lipopolysaccharides |
| post-AAA+ oligomerization domain-like | 0.007688 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins || Botulinum Toxins, Type A |
| alpha/beta knot | 0.007688 | INHERITED FROM: cylindrospermopsin |
| Somatomedin B domain | 0.01005 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins || Botulinum Toxins, Type A |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.0104 | INHERITED FROM: Endotoxins || Lipopolysaccharides |
| Hemopexin-like domain | 0.01077 | INHERITED FROM: Lipopolysaccharides |
| Flavoproteins | 0.01243 | INHERITED FROM: Endotoxins || Lipopolysaccharides |
| DNA clamp | 0.01505 | INHERITED FROM: cylindrospermopsin |
| Troponin coil-coiled subunits | 0.01505 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins || Botulinum Toxins, Type A |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.01792 | INHERITED FROM: cylindrospermopsin |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0.02065 | INHERITED FROM: Endotoxins || Lipopolysaccharides |
| Pectin lyase-like | 0.02515 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins || Botulinum Toxins, Type A |
| Tropomyosin | 0.02579 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins, Type A |
| Fibronectin type III | 0.04335 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins, Type A |
| L30e-like | 0.05707 | INHERITED FROM: cylindrospermopsin |
| Protein kinase-like (PK-like) | 0.1558 | INHERITED FROM: cholix toxin, Vibrio cholerae |
| Growth factor receptor domain | 0.2714 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins |
| P-loop containing nucleoside triphosphate hydrolases | 0.4922 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Duplex) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
49417,55550 49417 - p53-like transcription factors 55550 - SH2 domain | 0.000001333 | DIRECT |
48092,47655 48092 - Transcription factor STAT-4 N-domain 47655 - STAT | 0.000001333 | DIRECT |
47655,49417 47655 - STAT 49417 - p53-like transcription factors | 0.000001333 | DIRECT |
47986,52129 47986 - DEATH domain 52129 - Caspase-like | 0.000005593 | DIRECT |
47986,47986 47986 - DEATH domain 47986 - DEATH domain | 0.00003011 | DIRECT |
47113,-7 47113 - Histone-fold -7 - CATH | 0.0001182 | DIRECT |
49417,81296 49417 - p53-like transcription factors 81296 - E set domains | 0.0006758 | DIRECT |
53300,49899 53300 - vWA-like 49899 - Concanavalin A-like lectins/glucanases | 0.000751 | DIRECT |
82615,82615 82615 - Polo-box domain 82615 - Polo-box domain | 0.000751 | DIRECT |
49265,49265 49265 - Fibronectin type III 49265 - Fibronectin type III | 0.001372 | INHERITED FROM: Lipopolysaccharides |
57586,57586 57586 - TNF receptor-like 57586 - TNF receptor-like | 0.00258 | INHERITED FROM: lipopolysaccharide, E. coli O26-B6 || Lipopolysaccharides |
47090,55486 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain | 0.00258 | INHERITED FROM: Endotoxins || Lipopolysaccharides |
63501,50242 63501 - Frizzled cysteine-rich domain 50242 - TIMP-like | 0.004091 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins || Botulinum Toxins, Type A |
100920,100934 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.004091 | INHERITED FROM: Endotoxins || Lipopolysaccharides |
57440,57440 57440 - Kringle-like 57440 - Kringle-like | 0.006349 | INHERITED FROM: Lipopolysaccharides |
52540,48019 52540 - P-loop containing nucleoside triphosphate hydrolases 48019 - post-AAA+ oligomerization domain-like | 0.007688 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins || Botulinum Toxins, Type A |
90188,90188 90188 - Somatomedin B domain 90188 - Somatomedin B domain | 0.01505 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins || Botulinum Toxins, Type A |
53067,100920 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0.02065 | INHERITED FROM: Endotoxins || Lipopolysaccharides |
90257,90257 90257 - Myosin rod fragments 90257 - Myosin rod fragments | 0.02141 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins || Botulinum Toxins, Type A |
57184,49899 57184 - Growth factor receptor domain 49899 - Concanavalin A-like lectins/glucanases | 0.03591 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins || Botulinum Toxins, Type A |
52821,52799 52821 - Rhodanese/Cell cycle control phosphatase 52799 - (Phosphotyrosine protein) phosphatases II | 0.05604 | INHERITED FROM: cylindrospermopsin |
52113,52113 52113 - BRCT domain 52113 - BRCT domain | 0.06038 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins || Botulinum Toxins, Type A |
55486,50923 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0.06807 | INHERITED FROM: Endotoxins |
48726,49265 48726 - Immunoglobulin 49265 - Fibronectin type III | 0.08493 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins, Type A |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
49417,55550 49417 - p53-like transcription factors 55550 - SH2 domain | 0.000001333 | Direct |
48092,47655 48092 - Transcription factor STAT-4 N-domain 47655 - STAT | 0.000001333 | Direct |
47655,49417 47655 - STAT 49417 - p53-like transcription factors | 0.000001333 | Direct |
47986,52129 47986 - DEATH domain 52129 - Caspase-like | 0.000005593 | Direct |
47986,47986 47986 - DEATH domain 47986 - DEATH domain | 0.00003011 | Direct |
47113,-7 47113 - Histone-fold -7 - CATH | 0.0001182 | Direct |
49417,81296 49417 - p53-like transcription factors 81296 - E set domains | 0.0006758 | Direct |
53300,49899 53300 - vWA-like 49899 - Concanavalin A-like lectins/glucanases | 0.000751 | Direct |
82615,82615 82615 - Polo-box domain 82615 - Polo-box domain | 0.000751 | Direct |
49265,49265 49265 - Fibronectin type III 49265 - Fibronectin type III | 0.001372 | Inherited |
57586,57586 57586 - TNF receptor-like 57586 - TNF receptor-like | 0.00258 | Inherited |
47090,55486 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain | 0.00258 | Inherited |
63501,50242 63501 - Frizzled cysteine-rich domain 50242 - TIMP-like | 0.004091 | Inherited |
100920,100934 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.004091 | Inherited |
57440,57440 57440 - Kringle-like 57440 - Kringle-like | 0.006349 | Inherited |
52540,48019 52540 - P-loop containing nucleoside triphosphate hydrolases 48019 - post-AAA+ oligomerization domain-like | 0.007688 | Inherited |
90188,90188 90188 - Somatomedin B domain 90188 - Somatomedin B domain | 0.01505 | Inherited |
53067,100920 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0.02065 | Inherited |
90257,90257 90257 - Myosin rod fragments 90257 - Myosin rod fragments | 0.02141 | Inherited |
57184,49899 57184 - Growth factor receptor domain 49899 - Concanavalin A-like lectins/glucanases | 0.03591 | Inherited |
52821,52799 52821 - Rhodanese/Cell cycle control phosphatase 52799 - (Phosphotyrosine protein) phosphatases II | 0.05604 | Inherited |
52113,52113 52113 - BRCT domain 52113 - BRCT domain | 0.06038 | Inherited |
55486,50923 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0.06807 | Inherited |
48726,49265 48726 - Immunoglobulin 49265 - Fibronectin type III | 0.08493 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Triple) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
47986,47986,52129 47986 - DEATH domain 47986 - DEATH domain 52129 - Caspase-like | 0 | DIRECT |
48092,47655,49417 48092 - Transcription factor STAT-4 N-domain 47655 - STAT 49417 - p53-like transcription factors | 0.000001333 | DIRECT |
47655,49417,55550 47655 - STAT 49417 - p53-like transcription factors 55550 - SH2 domain | 0.000001333 | DIRECT |
53067,100920,100934 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.004091 | INHERITED FROM: Endotoxins || Lipopolysaccharides |
53067,53067,100920 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0.02065 | INHERITED FROM: Endotoxins || Lipopolysaccharides |
47090,55486,50923 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0.04914 | INHERITED FROM: Endotoxins || Lipopolysaccharides |
57586,57586,57586 57586 - TNF receptor-like 57586 - TNF receptor-like 57586 - TNF receptor-like | 0.06038 | INHERITED FROM: lipopolysaccharide, E. coli O26-B6 |
48726,48726,49265 48726 - Immunoglobulin 48726 - Immunoglobulin 49265 - Fibronectin type III | 0.1443 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins, Type A |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
47986,47986,52129 47986 - DEATH domain 47986 - DEATH domain 52129 - Caspase-like | 0 | Direct |
48092,47655,49417 48092 - Transcription factor STAT-4 N-domain 47655 - STAT 49417 - p53-like transcription factors | 0.000001333 | Direct |
47655,49417,55550 47655 - STAT 49417 - p53-like transcription factors 55550 - SH2 domain | 0.000001333 | Direct |
53067,100920,100934 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.004091 | Inherited |
53067,53067,100920 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0.02065 | Inherited |
47090,55486,50923 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0.04914 | Inherited |
57586,57586,57586 57586 - TNF receptor-like 57586 - TNF receptor-like 57586 - TNF receptor-like | 0.06038 | Inherited |
48726,48726,49265 48726 - Immunoglobulin 48726 - Immunoglobulin 49265 - Fibronectin type III | 0.1443 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Plot distribution on species Tree Of Life (sTOL) for Superfamily and/or Family domains annotated by this CC term
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Plot tree as:
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Download Newick format tree:
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( show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domain
architecture data for all genomes in SUPERFAMILY. The PAUP
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
Plot distribution on species Tree Of Life (sTOL) for single supra-domains annotated by this CC term
 |
Plot tree as:
| |
Download Newick format tree:
| |
Browsing in TREE OF LIFE:
|
( show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
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