Acting on CH or CH(2) groups

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children)	EC term [EC ID] <#Children>	(#SF|#FA)	#Supra-domain (Single|Duplex|Triple)
+ + 2:	root [root] <6>
+ 1:	Oxidoreductases [1] <23>	(183|263)	(202|169|83)
0:	Acting on CH or CH(2) groups [1.17] <7>	(13|13)	(18|15|6)
- 1:	With NAD(+) or NADP(+) as acceptor [1.17.1] <7>	(6|6)	(7|6|5)
- 1:	With other acceptors [1.17.99] <5>	(0|0)	(2|2|1)
- 1:	With a disulfide as acceptor [1.17.4] <3>	(3|4)	(5|2|0)
- 1:	With oxygen as acceptor [1.17.3] <3>	(6|6)	(6|5|4)
- 1:	With a quinone or similar compound as acceptor [1.17.5] <2>	(0|0)	(0|0|0)
- 1:	With an iron-sulfur protein as acceptor [1.17.7] <2>	(4|3)	(4|5|0)
- 1:	With a cytochrome as acceptor [1.17.2] <1>	(0|0)	(0|0|0)

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Superfamily

Superfamily domains annotated to this EC term (SDEO level: Informative)
Highlighted in gray are those with FDR_all>0.001

SCOP term	FDR (all)	Annotation (direct or inherited)
Dihydropteroate synthetase-like	0	DIRECT
R1 subunit of ribonucleotide reductase, N-terminal domain	0	DIRECT
Nitrite and sulphite reductase 4Fe-4S domain-like	0	DIRECT
PFL-like glycyl radical enzymes	0	DIRECT
Ferritin-like	0	DIRECT
Molybdenum cofactor-binding domain	0	DIRECT
CO dehydrogenase flavoprotein C-terminal domain-like	0	DIRECT
CO dehydrogenase molybdoprotein N-domain-like	0	DIRECT
Enolase C-terminal domain-like	0	DIRECT
CO dehydrogenase ISP C-domain like	7.054e-16	DIRECT
Inosine monophosphate dehydrogenase (IMPDH)	0.0000001951	DIRECT
2Fe-2S ferredoxin-like	0.000003125	DIRECT
FAD-binding/transporter-associated domain-like	0.02818	INHERITED FROM: With oxygen as acceptor || With NAD(+) or NADP(+) as acceptor

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Family

Family domains annotated to this (SDEO level: Informative)
Highlighted in gray are those with FDR_all>0.001

SCOP term	FDR (all)	Annotation (direct or inherited)
CO dehydrogenase flavoprotein N-terminal domain-like	0	DIRECT
CO dehydrogenase molybdoprotein N-domain-like	0	DIRECT
R1 subunit of ribonucleotide reductase, C-terminal domain	0	DIRECT
Nitrite and sulphite reductase 4Fe-4S domain-like	0	DIRECT
Ribonucleotide reductase-like	0	DIRECT
R1 subunit of ribonucleotide reductase, N-terminal domain	0	DIRECT
B12-dependent (class II) ribonucleotide reductase	0	DIRECT
CO dehydrogenase flavoprotein C-terminal domain-like	0	DIRECT
Molybdenum cofactor-binding domain	0	DIRECT
CO dehydrogenase ISP C-domain like	5.205e-16	DIRECT
Dihydropteroate synthetase	0.0000000000000556	DIRECT
2Fe-2S ferredoxin domains from multidomain proteins	0.00000001958	DIRECT
Inosine monophosphate dehydrogenase (IMPDH)	0.005057	INHERITED FROM: (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synth || With an iron-sulfur protein as acceptor

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Supra-domain (including individual superfamily)

Supra-domains annotated to this EC term (SPEO level: Informative)
Highlighted in gray are those with FDR>0.001

Supra-domain (Single)	FDR (all)	Annotation (direct or inherited)
Dihydropteroate synthetase-like	0	DIRECT
Enolase C-terminal domain-like	0	DIRECT
Ferritin-like	0	DIRECT
Nitrite and sulphite reductase 4Fe-4S domain-like	0	DIRECT
Molybdenum cofactor-binding domain	0	DIRECT
PFL-like glycyl radical enzymes	0	DIRECT
CO dehydrogenase ISP C-domain like	0	DIRECT
CO dehydrogenase flavoprotein C-terminal domain-like	0	DIRECT
YebC-like	0	DIRECT
R1 subunit of ribonucleotide reductase, N-terminal domain	0	DIRECT
CO dehydrogenase molybdoprotein N-domain-like	0	DIRECT
2Fe-2S ferredoxin-like	0.00000002382	DIRECT
Inosine monophosphate dehydrogenase (IMPDH)	0.0000001749	DIRECT
Hedgehog/intein (Hint) domain	0.0000632	DIRECT
FAD-binding/transporter-associated domain-like	0.00405	INHERITED FROM: Xanthine dehydrogenase || With oxygen as acceptor || With NAD(+) or NADP(+) as acceptor
Acyl-CoA dehydrogenase NM domain-like	0.07064	INHERITED FROM: 24-hydroxylase || With other acceptors
Acyl-CoA dehydrogenase C-terminal domain-like	0.07336	INHERITED FROM: 24-hydroxylase || With other acceptors
Nucleic acid-binding proteins	1	INHERITED FROM: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Supra-domains annotated to this EC term (SPEO level: Informative)
Highlighted in gray are those with FDR>0.001

Supra-domain (Duplex) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
56176,55447 56176 - FAD-binding/transporter-associated domain-like 55447 - CO dehydrogenase flavoprotein C-terminal domain-like	0	DIRECT
54665,56003 54665 - CO dehydrogenase molybdoprotein N-domain-like 56003 - Molybdenum cofactor-binding domain	0	DIRECT
51366,56014 51366 - Ribulose-phoshate binding barrel 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like	0	DIRECT
54292,47741 54292 - 2Fe-2S ferredoxin-like 47741 - CO dehydrogenase ISP C-domain like	0	DIRECT
48168,51998 48168 - R1 subunit of ribonucleotide reductase, N-terminal domain 51998 - PFL-like glycyl radical enzymes	0	DIRECT
75625,51998 75625 - YebC-like 51998 - PFL-like glycyl radical enzymes	0	DIRECT
51412,56014 51412 - Inosine monophosphate dehydrogenase (IMPDH) 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like	0	DIRECT
51717,56014 51717 - Dihydropteroate synthetase-like 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like	0	DIRECT
51604,56014 51604 - Enolase C-terminal domain-like 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like	0	DIRECT
47741,56176 47741 - CO dehydrogenase ISP C-domain like 56176 - FAD-binding/transporter-associated domain-like	0	DIRECT
51395,56014 51395 - FMN-linked oxidoreductases 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like	0	DIRECT
55447,54665 55447 - CO dehydrogenase flavoprotein C-terminal domain-like 54665 - CO dehydrogenase molybdoprotein N-domain-like	0.00000000000001034	DIRECT
50249,50249 50249 - Nucleic acid-binding proteins 50249 - Nucleic acid-binding proteins	0.0002693	DIRECT
47203,47203 47203 - Acyl-CoA dehydrogenase C-terminal domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like	0.002492	INHERITED FROM: 24-hydroxylase || With other acceptors
56645,47203 56645 - Acyl-CoA dehydrogenase NM domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like	0.07064	INHERITED FROM: 24-hydroxylase || With other acceptors

Supra-domains annotated to this EC term (SPEO level: Informative)
Highlighted in gray are those with FDR>0.001

Supra-domain (Triple) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
50249,50249,50249 50249 - Nucleic acid-binding proteins 50249 - Nucleic acid-binding proteins 50249 - Nucleic acid-binding proteins	0	DIRECT
47741,56176,55447 47741 - CO dehydrogenase ISP C-domain like 56176 - FAD-binding/transporter-associated domain-like 55447 - CO dehydrogenase flavoprotein C-terminal domain-like	0	DIRECT
54292,47741,56176 54292 - 2Fe-2S ferredoxin-like 47741 - CO dehydrogenase ISP C-domain like 56176 - FAD-binding/transporter-associated domain-like	0	DIRECT
56176,55447,54665 56176 - FAD-binding/transporter-associated domain-like 55447 - CO dehydrogenase flavoprotein C-terminal domain-like 54665 - CO dehydrogenase molybdoprotein N-domain-like	0.00000000000001034	DIRECT
55447,54665,56003 55447 - CO dehydrogenase flavoprotein C-terminal domain-like 54665 - CO dehydrogenase molybdoprotein N-domain-like 56003 - Molybdenum cofactor-binding domain	0.00000000000001034	DIRECT
56645,47203,47203 56645 - Acyl-CoA dehydrogenase NM domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like	0.002492	INHERITED FROM: 24-hydroxylase || With other acceptors