DNA polymerase III chi subunit superfamily

SCOP classification

• Root: SCOP hierarchy in SUPERFAMILY [ 0] (11)
• Class: Alpha and beta proteins (a/b) [ 51349] (147)
• Fold: DNA polymerase III chi subunit [ 102399]
• Superfamily: DNA polymerase III chi subunit [ 102400]
• Families: DNA polymerase III chi subunit [ 102401]

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Superfamily statistics

	Genomes (932)	Uniprot 2018_03 genome	PDB chains (SCOP 1.75)
Domains	934	7,539	1
Proteins	934	7,537	1

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Functional annotation

• General category: Information
• Detailed category: DNA replication/repair

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Enzyme Commission (EC)

Highlighted in gray are those with FDR_all>0.001

	EC term	FDR (all)	IC level	SDEC level	Annotation (direct or inherited)
Enzyme Commission (EC)	Transferases	0	0.3035	--	DIRECT
Enzyme Commission (EC)	Transferring phosphorus-containing groups	0	0.5453	Least Informative	DIRECT
Enzyme Commission (EC)	Nucleotidyltransferases	0	0.9432	Moderately Informative	DIRECT
Enzyme Commission (EC)	DNA-directed DNA polymerase	0	1.59	Informative	DIRECT

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InterPro annotation

• Cross references: IPR007459 SSF102400 Protein matches
• Abstract: The DNA polymerase III holoenzyme is the polymerase responsible for the replication of the Escherichia coli chromosome. The holoenzyme is composed of the DNA polymerase III core, the sliding clamp, and the DnaX clamp loading complex. The DnaX complex contains either the tau or gamma product of gene dnax, complexed to delta.delta and to chi psi. Chi forms a 1:1 heterodimer with psi. The chi psi complex functions by increasing the affinity of tau and gamma for delta.delta allowing a functional clamp-loading complex to form at physiological subunit concentrations. Psi is responsible for the interaction with DnaX (gamma/tau), but psi is insoluble unless it is in a complex with chi [7494000].

InterPro database

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