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Enzyme Commission (EC): Acting on acid anhydrides 
(show info)
Biomedical Ontology
Like Gene Ontology (GO), biomedical ontology such as phenotype ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Biomedical ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI’s thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology Based on YP which is the major contributor to the ‘Ascomycete phenotype ontology’, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- UniProtKB KeyWords (KW) Ontology Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- CTD Diseases (CD) Ontology CD is MEDIC disease vocabulary that is modified by CTD from the "Diseases" [C] branch of Medical Subject Headings (MeSH), combined with genetic disorders from the Online Mendelian Inheritance in OMIM database.
- CTD Chemicals (CC) Ontology CC is chemical vocabulary that is adapted by CTD from the "Chemicals and Drugs" category and Supplementary Concept Records of Medical Subject Headings (MeSH, a hierarchical vocabulary used to index articles for MEDLINE/PubMed).
Jump to [ Top · Hierarchy · Annotations ]
Root: EC Hierarchy (from IntEnz release 70)
Jump to [ Top · Hierarchy ]
Superfamily( show details)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| Nucleic acid-binding proteins | 0 | DIRECT |
| "Winged helix" DNA-binding domain | 0 | DIRECT |
| Apyrase | 0 | DIRECT |
| EF-G C-terminal domain-like | 0 | DIRECT |
| C-terminal domain of Ku80 | 0 | DIRECT |
| RuvA domain 2-like | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Positive stranded ssRNA viruses | 0 | DIRECT |
| Nudix | 0 | DIRECT |
| mRNA decapping enzyme DcpS N-terminal domain | 0 | DIRECT |
| EndoU-like | 0 | DIRECT |
| Dcp2 domain-like | 0 | DIRECT |
| N-terminal domain of DnaB helicase | 0 | DIRECT |
| Acylphosphatase/BLUF domain-like | 0 | DIRECT |
| Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
| all-alpha NTP pyrophosphatases | 0 | DIRECT |
| ITPase-like | 0 | DIRECT |
| HIT-like | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| Flavivirus capsid protein C | 0 | DIRECT |
| DHH phosphoesterases | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Viral leader polypeptide zinc finger | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| DNA primase core | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Rap30/74 interaction domains | 0 | DIRECT |
| DNA helicase RuvA subunit, C-terminal domain | 0 | DIRECT |
| P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
| Inorganic pyrophosphatase | 0 | DIRECT |
| Origin of replication-binding domain, RBD-like | 0 | DIRECT |
| Initiation factor IF2/eIF5b, domain 3 | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| Translation proteins | 0 | DIRECT |
| Viral glycoprotein, central and dimerisation domains | 0 | DIRECT |
| Metallo-dependent phosphatases | 0 | DIRECT |
| dUTPase-like | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| Trypsin-like serine proteases | 0.00000000000002806 | DIRECT |
| vWA-like | 0.0000000000001715 | DIRECT |
| Tudor/PWWP/MBT | 0.00000000007254 | DIRECT |
| HMA, heavy metal-associated domain | 0.0000000003308 | DIRECT |
| SAP domain | 0.000000007375 | DIRECT |
| Replicase NSP9 | 0.00000001504 | DIRECT |
| Coronavirus NSP10-like | 0.00000001504 | DIRECT |
| Coronavirus NSP8-like | 0.00000001504 | DIRECT |
| Coronavirus NSP7-like | 0.00000001504 | DIRECT |
| Prokaryotic type I DNA topoisomerase | 0.00000002077 | DIRECT |
| MIT domain | 0.00000003368 | DIRECT |
| SCOP hierarchy in SUPERFAMILY | 0.00000003907 | DIRECT |
| E set domains | 0.0000000759 | DIRECT |
| Homing endonucleases | 0.0000002979 | DIRECT |
| HRDC-like | 0.000001084 | DIRECT |
| Hedgehog/intein (Hint) domain | 0.00000149 | DIRECT |
| NSP3A-like | 0.000007894 | DIRECT |
| F-box domain | 0.00001953 | DIRECT |
| RNA-binding domain, RBD | 0.00007272 | DIRECT |
| Somatomedin B domain | 0.000095 | DIRECT |
| FYVE/PHD zinc finger | 0.000257 | DIRECT |
| R3H domain | 0.0005598 | DIRECT |
| CYTH-like phosphatases | 0.002048 | INHERITED FROM: Thiamine-triphosphatase || Triphosphatase || In phosphorus-containing anhydrides |
| Bromodomain | 0.002075 | INHERITED FROM: Adenosinetriphosphatase |
| His-Me finger endonucleases | 0.002095 | INHERITED FROM: Nucleotide diphosphatase || In phosphorus-containing anhydrides |
| post-AAA+ oligomerization domain-like | 0.003208 | INHERITED FROM: Adenosinetriphosphatase || In phosphorus-containing anhydrides |
| Ankyrin repeat | 0.003949 | INHERITED FROM: NAD(+) diphosphatase || Adenosinetriphosphatase |
| WW domain | 0.01106 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement || RNA helicase |
| SARS Nsp1-like | 0.01418 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement || DNA helicase || RNA helicase |
| Ribonuclease Rh-like | 0.01747 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement || Nucleoside-triphosphate phosphatase || RNA helicase || In phosphorus-containing anhydrides |
| CCCH zinc finger | 0.06486 | INHERITED FROM: RNA helicase |
| 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0.07683 | INHERITED FROM: Apyrase || UDP-sugar diphosphatase || In phosphorus-containing anhydrides |
| Retrovirus zinc finger-like domains | 0.1237 | INHERITED FROM: dUTP diphosphatase || RNA helicase |
| ADC-like | 0.1738 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement || Vesicle-fusing ATPase |
| HD-domain/PDEase-like | 0.2032 | INHERITED FROM: Guanosine-5'-triphosphate,3'-diphosphate diphosphatase || Exopolyphosphatase || In phosphorus-containing anhydrides |
| UBA-like | 0.2173 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement |
| Calcium ATPase, transduction domain A | 0.2348 | INHERITED FROM: Acting on acid anhydrides; catalyzing transmembrane movement of substances |
| Calcium ATPase, transmembrane domain M | 0.2379 | INHERITED FROM: Acting on acid anhydrides; catalyzing transmembrane movement of substances |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0.284 | INHERITED FROM: Undecaprenyl-diphosphate phosphatase || Dolichyldiphosphatase || In phosphorus-containing anhydrides |
| NTF2-like | 0.2943 | INHERITED FROM: RNA helicase |
| Actin-like ATPase domain | 0.4656 | INHERITED FROM: Guanosine-5'-triphosphate,3'-diphosphate diphosphatase || Non-chaperonin molecular chaperone ATPase || Adenosinetriphosphatase || Exopolyphosphatase || In phosphorus-containing anhydrides |
| Retrovirus capsid dimerization domain-like | 0.6318 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
| Clavaminate synthase-like | 0.6437 | INHERITED FROM: RNA helicase |
| HisI-like | 0.7675 | INHERITED FROM: Phosphoribosyl-ATP diphosphatase || In phosphorus-containing anhydrides |
| Retrovirus capsid protein, N-terminal core domain | 0.9467 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
| N-terminal Zn binding domain of HIV integrase | 0.9795 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
| PH domain-like | 1 | INHERITED FROM: Dynamin GTPase || Acting on GTP; involved in cellular and subcellular movement |
| Cysteine proteinases | 1 | INHERITED FROM: Nucleoside-triphosphate phosphatase |
| S-adenosyl-L-methionine-dependent methyltransferases | 1 | INHERITED FROM: Nucleoside-triphosphate phosphatase || RNA helicase |
| Retroviral matrix proteins | 1 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
| Alkaline phosphatase-like | 1 | INHERITED FROM: Nucleotide diphosphatase || Bis(5'-adenosyl)-triphosphatase |
| HAD-like | 1 | INHERITED FROM: Inorganic diphosphatase || Acting on acid anhydrides; catalyzing transmembrane movement of substances |
| Ribonuclease H-like | 1 | INHERITED FROM: dUTP diphosphatase |
| SurE-like | 1 | INHERITED FROM: Exopolyphosphatase || In phosphorus-containing anhydrides |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | INHERITED FROM: Adenosinetriphosphatase |
| Acid proteases | 1 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
| Macro domain-like | 1 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement || Nucleoside-triphosphate phosphatase || RNA helicase |
| DNA-binding domain of retroviral integrase | 1 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| Nucleic acid-binding proteins | 0 | Direct |
| "Winged helix" DNA-binding domain | 0 | Direct |
| Apyrase | 0 | Direct |
| EF-G C-terminal domain-like | 0 | Direct |
| C-terminal domain of Ku80 | 0 | Direct |
| RuvA domain 2-like | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Positive stranded ssRNA viruses | 0 | Direct |
| Nudix | 0 | Direct |
| mRNA decapping enzyme DcpS N-terminal domain | 0 | Direct |
| EndoU-like | 0 | Direct |
| Dcp2 domain-like | 0 | Direct |
| N-terminal domain of DnaB helicase | 0 | Direct |
| Acylphosphatase/BLUF domain-like | 0 | Direct |
| Soluble domain of poliovirus core protein 3a | 0 | Direct |
| all-alpha NTP pyrophosphatases | 0 | Direct |
| ITPase-like | 0 | Direct |
| HIT-like | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| Flavivirus capsid protein C | 0 | Direct |
| DHH phosphoesterases | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Viral leader polypeptide zinc finger | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| DNA primase core | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Rap30/74 interaction domains | 0 | Direct |
| DNA helicase RuvA subunit, C-terminal domain | 0 | Direct |
| P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
| Inorganic pyrophosphatase | 0 | Direct |
| Origin of replication-binding domain, RBD-like | 0 | Direct |
| Initiation factor IF2/eIF5b, domain 3 | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| Translation proteins | 0 | Direct |
| Viral glycoprotein, central and dimerisation domains | 0 | Direct |
| Metallo-dependent phosphatases | 0 | Direct |
| dUTPase-like | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| BRK domain-like | 0 | Direct |
| Trypsin-like serine proteases | 0.00000000000002806 | Direct |
| vWA-like | 0.0000000000001715 | Direct |
| Tudor/PWWP/MBT | 0.00000000007254 | Direct |
| HMA, heavy metal-associated domain | 0.0000000003308 | Direct |
| SAP domain | 0.000000007375 | Direct |
| Replicase NSP9 | 0.00000001504 | Direct |
| Coronavirus NSP10-like | 0.00000001504 | Direct |
| Coronavirus NSP8-like | 0.00000001504 | Direct |
| Coronavirus NSP7-like | 0.00000001504 | Direct |
| Prokaryotic type I DNA topoisomerase | 0.00000002077 | Direct |
| MIT domain | 0.00000003368 | Direct |
| SCOP hierarchy in SUPERFAMILY | 0.00000003907 | Direct |
| E set domains | 0.0000000759 | Direct |
| Homing endonucleases | 0.0000002979 | Direct |
| HRDC-like | 0.000001084 | Direct |
| Hedgehog/intein (Hint) domain | 0.00000149 | Direct |
| NSP3A-like | 0.000007894 | Direct |
| F-box domain | 0.00001953 | Direct |
| RNA-binding domain, RBD | 0.00007272 | Direct |
| Somatomedin B domain | 0.000095 | Direct |
| FYVE/PHD zinc finger | 0.000257 | Direct |
| R3H domain | 0.0005598 | Direct |
| CYTH-like phosphatases | 0.002048 | Inherited |
| Bromodomain | 0.002075 | Inherited |
| His-Me finger endonucleases | 0.002095 | Inherited |
| post-AAA+ oligomerization domain-like | 0.003208 | Inherited |
| Ankyrin repeat | 0.003949 | Inherited |
| WW domain | 0.01106 | Inherited |
| SARS Nsp1-like | 0.01418 | Inherited |
| Ribonuclease Rh-like | 0.01747 | Inherited |
| CCCH zinc finger | 0.06486 | Inherited |
| 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0.07683 | Inherited |
| Retrovirus zinc finger-like domains | 0.1237 | Inherited |
| ADC-like | 0.1738 | Inherited |
| HD-domain/PDEase-like | 0.2032 | Inherited |
| UBA-like | 0.2173 | Inherited |
| Calcium ATPase, transduction domain A | 0.2348 | Inherited |
| Calcium ATPase, transmembrane domain M | 0.2379 | Inherited |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0.284 | Inherited |
| NTF2-like | 0.2943 | Inherited |
| Actin-like ATPase domain | 0.4656 | Inherited |
| Retrovirus capsid dimerization domain-like | 0.6318 | Inherited |
| Clavaminate synthase-like | 0.6437 | Inherited |
| HisI-like | 0.7675 | Inherited |
| Retrovirus capsid protein, N-terminal core domain | 0.9467 | Inherited |
| N-terminal Zn binding domain of HIV integrase | 0.9795 | Inherited |
| PH domain-like | 1 | Inherited |
| Cysteine proteinases | 1 | Inherited |
| S-adenosyl-L-methionine-dependent methyltransferases | 1 | Inherited |
| Retroviral matrix proteins | 1 | Inherited |
| Alkaline phosphatase-like | 1 | Inherited |
| HAD-like | 1 | Inherited |
| Ribonuclease H-like | 1 | Inherited |
| SurE-like | 1 | Inherited |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | Inherited |
| Acid proteases | 1 | Inherited |
| Macro domain-like | 1 | Inherited |
| DNA-binding domain of retroviral integrase | 1 | Inherited |
LINKTO: Domain2BO Download and Domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Family( show details)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| ITPase (Ham1) | 0 | DIRECT |
| Exodeoxyribonuclease V beta chain (RecB), C-terminal domain | 0 | DIRECT |
| Tandem AAA-ATPase domain | 0 | DIRECT |
| ADPRibase-Mn-like | 0 | DIRECT |
| HIT (HINT, histidine triad) family of protein kinase-interacting proteins | 0 | DIRECT |
| CDH-like | 0 | DIRECT |
| XPF/Rad1/Mus81 nuclease | 0 | DIRECT |
| Ppx/GppA phosphatase | 0 | DIRECT |
| Viral proteases | 0 | DIRECT |
| GUCT domain | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| Viral cysteine protease of trypsin fold | 0 | DIRECT |
| Elongation factors | 0 | DIRECT |
| RecQ helicase DNA-binding domain-like | 0 | DIRECT |
| mRNA decapping enzyme DcpS C-terminal domain | 0 | DIRECT |
| mRNA decapping enzyme DcpS N-terminal domain | 0 | DIRECT |
| Apyrase | 0 | DIRECT |
| MgsA/YrvN C-terminal domain-like | 0 | DIRECT |
| Initiation factor IF2/eIF5b, domain 3 | 0 | DIRECT |
| FMDV leader protease | 0 | DIRECT |
| RNA helicase | 0 | DIRECT |
| Sec63 C-terminal domain-like | 0 | DIRECT |
| Dcp2 box A domain | 0 | DIRECT |
| Ku70 subunit middle domain | 0 | DIRECT |
| Sec63 N-terminal domain | 0 | DIRECT |
| Nsp15 N-terminal domain-like | 0 | DIRECT |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Viral glycoprotein, central and dimerisation domains | 0 | DIRECT |
| DNA-binding domain from rap30 | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| Ku70 subunit N-terminal domain | 0 | DIRECT |
| C-terminal domain of Ku80 | 0 | DIRECT |
| Picornaviridae-like VP (VP1, VP2, VP3 and VP4) | 0 | DIRECT |
| Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
| Replication initiation protein E1 | 0 | DIRECT |
| Actin/HSP70 | 0 | DIRECT |
| Class II viral fusion proteins C-terminal domain | 0 | DIRECT |
| Cdc48 N-terminal domain-like | 0 | DIRECT |
| Flavivirus capsid protein C | 0 | DIRECT |
| HRDC domain from helicases | 0 | DIRECT |
| Chromo domain | 0 | DIRECT |
| Caliciviridae-like VP | 0 | DIRECT |
| Nsp15 C-terminal domain-like | 0 | DIRECT |
| G proteins | 0 | DIRECT |
| NADH pyrophosphatase | 0 | DIRECT |
| DNA helicase RuvA subunit, middle domain | 0 | DIRECT |
| Achaeal helicase C-terminal domain | 0 | DIRECT |
| MutT-like | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| Helicase-like "domain" of reverse gyrase | 0 | DIRECT |
| mRNA decapping enzyme-like | 0 | DIRECT |
| DNA helicase RuvA subunit, C-terminal domain | 0 | DIRECT |
| Ppx associated domain | 0 | DIRECT |
| Ku80 subunit middle domain | 0 | DIRECT |
| MazG-like | 0 | DIRECT |
| RecG "wedge" domain | 0 | DIRECT |
| Macro domain | 0 | DIRECT |
| DNA helicase RuvA subunit, N-terminal domain | 0 | DIRECT |
| Helicase DNA-binding domain | 0 | DIRECT |
| Rap30/74 interaction domains | 0 | DIRECT |
| Maf-like | 0 | DIRECT |
| N-terminal domain of DnaB helicase | 0 | DIRECT |
| mRNA cap methylase | 0 | DIRECT |
| Inorganic pyrophosphatase | 0 | DIRECT |
| RNA-dependent RNA-polymerase | 0 | DIRECT |
| Acylphosphatase-like | 0 | DIRECT |
| TIP49 domain | 0 | DIRECT |
| Viral leader polypeptide zinc finger | 0 | DIRECT |
| dUTPase-like | 0 | DIRECT |
| Extended AAA-ATPase domain | 0 | DIRECT |
| Ku80 subunit N-terminal domain | 0 | DIRECT |
| HisE-like (PRA-PH) | 0 | DIRECT |
| EF-G/eEF-2 domains III and V | 0 | DIRECT |
| Manganese-dependent inorganic pyrophosphatase (family II) | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| CYTH domain | 0.000000000000001463 | DIRECT |
| Mason-Pfizer monkey virus matrix protein | 0.0000000000226 | DIRECT |
| HMA, heavy metal-associated domain | 0.000000000138 | DIRECT |
| SAP domain | 0.000000003152 | DIRECT |
| Coronavirus NSP7-like | 0.000000003491 | DIRECT |
| Coronavirus NSP10-like | 0.000000003491 | DIRECT |
| Coronavirus NSP8-like | 0.000000003491 | DIRECT |
| Replicase NSP9 | 0.000000003491 | DIRECT |
| MIT domain | 0.000000007073 | DIRECT |
| Prokaryotic type I DNA topoisomerase | 0.000000008891 | DIRECT |
| Tudor domain | 0.00000181 | DIRECT |
| NSP3A-like | 0.000002782 | DIRECT |
| Intein (protein splicing domain) | 0.000003518 | DIRECT |
| F-box domain | 0.00001364 | DIRECT |
| Somatomedin B domain | 0.0000513 | DIRECT |
| AlkB-like | 0.0001434 | DIRECT |
| Protein serine/threonine phosphatase | 0.0002872 | DIRECT |
| R3H domain | 0.000314 | DIRECT |
| Bromodomain | 0.001422 | INHERITED FROM: Adenosinetriphosphatase |
| PHD domain | 0.001544 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement || DNA helicase |
| Ankyrin repeat | 0.002141 | INHERITED FROM: NAD(+) diphosphatase || Adenosinetriphosphatase |
| WW domain | 0.007869 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement || RNA helicase |
| SARS Nsp1-like | 0.009821 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement || DNA helicase || RNA helicase |
| Ribonuclease Rh-like | 0.01281 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement || Nucleoside-triphosphate phosphatase || RNA helicase || In phosphorus-containing anhydrides |
| SPRY domain | 0.0148 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement || RNA helicase |
| Pleckstrin-homology domain (PH domain) | 0.04578 | INHERITED FROM: Dynamin GTPase || Acting on GTP; involved in cellular and subcellular movement |
| CCCH zinc finger | 0.05112 | INHERITED FROM: RNA helicase |
| 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0.05136 | INHERITED FROM: Apyrase || UDP-sugar diphosphatase || In phosphorus-containing anhydrides |
| 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain | 0.05136 | INHERITED FROM: Apyrase || UDP-sugar diphosphatase || In phosphorus-containing anhydrides |
| Meta-cation ATPase, catalytic domain P | 0.05566 | INHERITED FROM: Acting on acid anhydrides; catalyzing transmembrane movement of substances |
| Retrovirus zinc finger-like domains | 0.06424 | INHERITED FROM: dUTP diphosphatase || RNA helicase |
| NagD-like | 0.1225 | INHERITED FROM: Inorganic diphosphatase || In phosphorus-containing anhydrides |
| Calcium ATPase, transduction domain A | 0.23 | INHERITED FROM: Acting on acid anhydrides; catalyzing transmembrane movement of substances |
| Canonical RBD | 0.2346 | INHERITED FROM: RNA helicase |
| Retrovirus capsid protein C-terminal domain | 0.487 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
| HisI-like | 0.535 | INHERITED FROM: Phosphoribosyl-ATP diphosphatase || In phosphorus-containing anhydrides |
| beta-Phosphoglucomutase-like | 0.6067 | INHERITED FROM: Inorganic diphosphatase || In phosphorus-containing anhydrides |
| RecA protein-like (ATPase-domain) | 0.6588 | INHERITED FROM: Nucleoside-triphosphate phosphatase |
| Calcium ATPase, transmembrane domain M | 0.6916 | INHERITED FROM: Acting on acid anhydrides; catalyzing transmembrane movement of substances |
| Retroviral protease (retropepsin) | 0.7122 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
| L-histidinol dehydrogenase HisD | 0.779 | INHERITED FROM: Phosphoribosyl-ATP diphosphatase |
| Retrovirus capsid protein, N-terminal core domain | 0.7798 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
| N-terminal Zn binding domain of HIV integrase | 0.8565 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
| DNA-binding domain of retroviral integrase | 0.8843 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
| Ribonuclease H | 1 | INHERITED FROM: dUTP diphosphatase |
| Retroviral integrase, catalytic domain | 1 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
| SurE-like | 1 | INHERITED FROM: Exopolyphosphatase || In phosphorus-containing anhydrides |
| Reverse transcriptase | 1 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| ITPase (Ham1) | 0 | Direct |
| Exodeoxyribonuclease V beta chain (RecB), C-terminal domain | 0 | Direct |
| Tandem AAA-ATPase domain | 0 | Direct |
| ADPRibase-Mn-like | 0 | Direct |
| HIT (HINT, histidine triad) family of protein kinase-interacting proteins | 0 | Direct |
| CDH-like | 0 | Direct |
| XPF/Rad1/Mus81 nuclease | 0 | Direct |
| Ppx/GppA phosphatase | 0 | Direct |
| Viral proteases | 0 | Direct |
| GUCT domain | 0 | Direct |
| BRK domain-like | 0 | Direct |
| Viral cysteine protease of trypsin fold | 0 | Direct |
| Elongation factors | 0 | Direct |
| RecQ helicase DNA-binding domain-like | 0 | Direct |
| mRNA decapping enzyme DcpS C-terminal domain | 0 | Direct |
| mRNA decapping enzyme DcpS N-terminal domain | 0 | Direct |
| Apyrase | 0 | Direct |
| MgsA/YrvN C-terminal domain-like | 0 | Direct |
| Initiation factor IF2/eIF5b, domain 3 | 0 | Direct |
| FMDV leader protease | 0 | Direct |
| RNA helicase | 0 | Direct |
| Sec63 C-terminal domain-like | 0 | Direct |
| Dcp2 box A domain | 0 | Direct |
| Ku70 subunit middle domain | 0 | Direct |
| Sec63 N-terminal domain | 0 | Direct |
| Nsp15 N-terminal domain-like | 0 | Direct |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Viral glycoprotein, central and dimerisation domains | 0 | Direct |
| DNA-binding domain from rap30 | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| Ku70 subunit N-terminal domain | 0 | Direct |
| C-terminal domain of Ku80 | 0 | Direct |
| Picornaviridae-like VP (VP1, VP2, VP3 and VP4) | 0 | Direct |
| Soluble domain of poliovirus core protein 3a | 0 | Direct |
| Replication initiation protein E1 | 0 | Direct |
| Actin/HSP70 | 0 | Direct |
| Class II viral fusion proteins C-terminal domain | 0 | Direct |
| Cdc48 N-terminal domain-like | 0 | Direct |
| Flavivirus capsid protein C | 0 | Direct |
| HRDC domain from helicases | 0 | Direct |
| Chromo domain | 0 | Direct |
| Caliciviridae-like VP | 0 | Direct |
| Nsp15 C-terminal domain-like | 0 | Direct |
| G proteins | 0 | Direct |
| NADH pyrophosphatase | 0 | Direct |
| DNA helicase RuvA subunit, middle domain | 0 | Direct |
| Achaeal helicase C-terminal domain | 0 | Direct |
| MutT-like | 0 | Direct |
| NTF2-like | 0 | Direct |
| Helicase-like "domain" of reverse gyrase | 0 | Direct |
| mRNA decapping enzyme-like | 0 | Direct |
| DNA helicase RuvA subunit, C-terminal domain | 0 | Direct |
| Ppx associated domain | 0 | Direct |
| Ku80 subunit middle domain | 0 | Direct |
| MazG-like | 0 | Direct |
| RecG "wedge" domain | 0 | Direct |
| Macro domain | 0 | Direct |
| DNA helicase RuvA subunit, N-terminal domain | 0 | Direct |
| Helicase DNA-binding domain | 0 | Direct |
| Rap30/74 interaction domains | 0 | Direct |
| Maf-like | 0 | Direct |
| N-terminal domain of DnaB helicase | 0 | Direct |
| mRNA cap methylase | 0 | Direct |
| Inorganic pyrophosphatase | 0 | Direct |
| RNA-dependent RNA-polymerase | 0 | Direct |
| Acylphosphatase-like | 0 | Direct |
| TIP49 domain | 0 | Direct |
| Viral leader polypeptide zinc finger | 0 | Direct |
| dUTPase-like | 0 | Direct |
| Extended AAA-ATPase domain | 0 | Direct |
| Ku80 subunit N-terminal domain | 0 | Direct |
| HisE-like (PRA-PH) | 0 | Direct |
| EF-G/eEF-2 domains III and V | 0 | Direct |
| Manganese-dependent inorganic pyrophosphatase (family II) | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| CYTH domain | 0.000000000000001463 | Direct |
| Mason-Pfizer monkey virus matrix protein | 0.0000000000226 | Direct |
| HMA, heavy metal-associated domain | 0.000000000138 | Direct |
| SAP domain | 0.000000003152 | Direct |
| Coronavirus NSP7-like | 0.000000003491 | Direct |
| Coronavirus NSP10-like | 0.000000003491 | Direct |
| Coronavirus NSP8-like | 0.000000003491 | Direct |
| Replicase NSP9 | 0.000000003491 | Direct |
| MIT domain | 0.000000007073 | Direct |
| Prokaryotic type I DNA topoisomerase | 0.000000008891 | Direct |
| Tudor domain | 0.00000181 | Direct |
| NSP3A-like | 0.000002782 | Direct |
| Intein (protein splicing domain) | 0.000003518 | Direct |
| F-box domain | 0.00001364 | Direct |
| Somatomedin B domain | 0.0000513 | Direct |
| AlkB-like | 0.0001434 | Direct |
| Protein serine/threonine phosphatase | 0.0002872 | Direct |
| R3H domain | 0.000314 | Direct |
| Bromodomain | 0.001422 | Inherited |
| PHD domain | 0.001544 | Inherited |
| Ankyrin repeat | 0.002141 | Inherited |
| WW domain | 0.007869 | Inherited |
| SARS Nsp1-like | 0.009821 | Inherited |
| Ribonuclease Rh-like | 0.01281 | Inherited |
| SPRY domain | 0.0148 | Inherited |
| Pleckstrin-homology domain (PH domain) | 0.04578 | Inherited |
| CCCH zinc finger | 0.05112 | Inherited |
| 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0.05136 | Inherited |
| 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain | 0.05136 | Inherited |
| Meta-cation ATPase, catalytic domain P | 0.05566 | Inherited |
| Retrovirus zinc finger-like domains | 0.06424 | Inherited |
| NagD-like | 0.1225 | Inherited |
| Calcium ATPase, transduction domain A | 0.23 | Inherited |
| Canonical RBD | 0.2346 | Inherited |
| Retrovirus capsid protein C-terminal domain | 0.487 | Inherited |
| HisI-like | 0.535 | Inherited |
| beta-Phosphoglucomutase-like | 0.6067 | Inherited |
| RecA protein-like (ATPase-domain) | 0.6588 | Inherited |
| Calcium ATPase, transmembrane domain M | 0.6916 | Inherited |
| Retroviral protease (retropepsin) | 0.7122 | Inherited |
| L-histidinol dehydrogenase HisD | 0.779 | Inherited |
| Retrovirus capsid protein, N-terminal core domain | 0.7798 | Inherited |
| N-terminal Zn binding domain of HIV integrase | 0.8565 | Inherited |
| DNA-binding domain of retroviral integrase | 0.8843 | Inherited |
| Ribonuclease H | 1 | Inherited |
| Retroviral integrase, catalytic domain | 1 | Inherited |
| SurE-like | 1 | Inherited |
| Reverse transcriptase | 1 | Inherited |
LINKTO: Domain2BO Download and Domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Single)( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| EF-G C-terminal domain-like | 0 | DIRECT |
| Rap30/74 interaction domains | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| RuvA domain 2-like | 0 | DIRECT |
| Flavivirus capsid protein C | 0 | DIRECT |
| HIT-like | 0 | DIRECT |
| Metallo-dependent phosphatases | 0 | DIRECT |
| Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
| dUTPase-like | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| N-terminal domain of DnaB helicase | 0 | DIRECT |
| Viral glycoprotein, central and dimerisation domains | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| Positive stranded ssRNA viruses | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Translation proteins | 0 | DIRECT |
| Nudix | 0 | DIRECT |
| Origin of replication-binding domain, RBD-like | 0 | DIRECT |
| Nucleic acid-binding proteins | 0 | DIRECT |
| P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
| Initiation factor IF2/eIF5b, domain 3 | 0 | DIRECT |
| C-terminal domain of Ku80 | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| EndoU-like | 0 | DIRECT |
| DHH phosphoesterases | 0 | DIRECT |
| mRNA decapping enzyme DcpS N-terminal domain | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| "Winged helix" DNA-binding domain | 0 | DIRECT |
| Acylphosphatase/BLUF domain-like | 0 | DIRECT |
| DNA helicase RuvA subunit, C-terminal domain | 0 | DIRECT |
| Apyrase | 0 | DIRECT |
| Dcp2 domain-like | 0 | DIRECT |
| Inorganic pyrophosphatase | 0 | DIRECT |
| ITPase-like | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Viral leader polypeptide zinc finger | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| all-alpha NTP pyrophosphatases | 0 | DIRECT |
| DNA primase core | 0 | DIRECT |
| Trypsin-like serine proteases | 0.00000000000001978 | DIRECT |
| vWA-like | 0.0000000000001217 | DIRECT |
| Tudor/PWWP/MBT | 0.00000000005312 | DIRECT |
| HMA, heavy metal-associated domain | 0.0000000002445 | DIRECT |
| SAP domain | 0.000000005555 | DIRECT |
| Coronavirus NSP10-like | 0.00000001137 | DIRECT |
| Replicase NSP9 | 0.00000001137 | DIRECT |
| Coronavirus NSP7-like | 0.00000001137 | DIRECT |
| Coronavirus NSP8-like | 0.00000001137 | DIRECT |
| Prokaryotic type I DNA topoisomerase | 0.00000001573 | DIRECT |
| MIT domain | 0.00000002557 | DIRECT |
| E set domains | 0.00000005792 | DIRECT |
| Homing endonucleases | 0.0000002295 | DIRECT |
| HRDC-like | 0.000000844 | DIRECT |
| Hedgehog/intein (Hint) domain | 0.000001163 | DIRECT |
| NSP3A-like | 0.000006227 | DIRECT |
| F-box domain | 0.00001555 | DIRECT |
| RNA-binding domain, RBD | 0.00005837 | DIRECT |
| Somatomedin B domain | 0.0000765 | DIRECT |
| FYVE/PHD zinc finger | 0.0002089 | DIRECT |
| R3H domain | 0.0004584 | DIRECT |
| CYTH-like phosphatases | 0.001704 | INHERITED FROM: Thiamine-triphosphatase || Triphosphatase || In phosphorus-containing anhydrides |
| Bromodomain | 0.001727 | INHERITED FROM: Adenosinetriphosphatase |
| His-Me finger endonucleases | 0.001743 | INHERITED FROM: In phosphorus-containing anhydrides || Nucleotide diphosphatase |
| post-AAA+ oligomerization domain-like | 0.002681 | INHERITED FROM: In phosphorus-containing anhydrides || Adenosinetriphosphatase |
| Ankyrin repeat | 0.003305 | INHERITED FROM: NAD(+) diphosphatase || Adenosinetriphosphatase |
| WW domain | 0.00938 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement || RNA helicase |
| SARS Nsp1-like | 0.01206 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement || DNA helicase || RNA helicase |
| Ribonuclease Rh-like | 0.0149 | INHERITED FROM: Nucleoside-triphosphate phosphatase || Acting on ATP; involved in cellular and subcellular movement || In phosphorus-containing anhydrides || RNA helicase |
| CCCH zinc finger | 0.05626 | INHERITED FROM: RNA helicase |
| 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0.06675 | INHERITED FROM: UDP-sugar diphosphatase || In phosphorus-containing anhydrides || Apyrase |
| Retrovirus zinc finger-like domains | 0.1082 | INHERITED FROM: dUTP diphosphatase || RNA helicase |
| ADC-like | 0.1534 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement || Vesicle-fusing ATPase |
| HD-domain/PDEase-like | 0.1802 | INHERITED FROM: In phosphorus-containing anhydrides || Guanosine-5'-triphosphate,3'-diphosphate diphosphatase || Exopolyphosphatase |
| UBA-like | 0.193 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement |
| Calcium ATPase, transduction domain A | 0.209 | INHERITED FROM: Acting on acid anhydrides; catalyzing transmembrane movement of substances |
| Calcium ATPase, transmembrane domain M | 0.212 | INHERITED FROM: Acting on acid anhydrides; catalyzing transmembrane movement of substances |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0.2558 | INHERITED FROM: In phosphorus-containing anhydrides || Dolichyldiphosphatase || Undecaprenyl-diphosphate phosphatase |
| NTF2-like | 0.2653 | INHERITED FROM: RNA helicase |
| Actin-like ATPase domain | 0.4244 | INHERITED FROM: In phosphorus-containing anhydrides || Guanosine-5'-triphosphate,3'-diphosphate diphosphatase || Exopolyphosphatase || Non-chaperonin molecular chaperone ATPase || Adenosinetriphosphatase |
| Retrovirus capsid dimerization domain-like | 0.58 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
| Clavaminate synthase-like | 0.5909 | INHERITED FROM: RNA helicase |
| HisI-like | 0.7063 | INHERITED FROM: In phosphorus-containing anhydrides || Phosphoribosyl-ATP diphosphatase |
| Retrovirus capsid protein, N-terminal core domain | 0.8755 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
| N-terminal Zn binding domain of HIV integrase | 0.9067 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
| DNA-binding domain of retroviral integrase | 0.9283 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | INHERITED FROM: Adenosinetriphosphatase |
| PH domain-like | 1 | INHERITED FROM: Dynamin GTPase || Acting on GTP; involved in cellular and subcellular movement |
| Cysteine proteinases | 1 | INHERITED FROM: Nucleoside-triphosphate phosphatase |
| SurE-like | 1 | INHERITED FROM: In phosphorus-containing anhydrides || Exopolyphosphatase |
| Ribonuclease H-like | 1 | INHERITED FROM: dUTP diphosphatase |
| Acid proteases | 1 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
| Alkaline phosphatase-like | 1 | INHERITED FROM: Nucleotide diphosphatase || Bis(5'-adenosyl)-triphosphatase |
| Macro domain-like | 1 | INHERITED FROM: Nucleoside-triphosphate phosphatase || Acting on ATP; involved in cellular and subcellular movement || RNA helicase |
| S-adenosyl-L-methionine-dependent methyltransferases | 1 | INHERITED FROM: Nucleoside-triphosphate phosphatase || RNA helicase |
| Retroviral matrix proteins | 1 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
| HAD-like | 1 | INHERITED FROM: Inorganic diphosphatase || Acting on acid anhydrides; catalyzing transmembrane movement of substances |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| EF-G C-terminal domain-like | 0 | Direct |
| Rap30/74 interaction domains | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| BRK domain-like | 0 | Direct |
| RuvA domain 2-like | 0 | Direct |
| Flavivirus capsid protein C | 0 | Direct |
| HIT-like | 0 | Direct |
| Metallo-dependent phosphatases | 0 | Direct |
| Soluble domain of poliovirus core protein 3a | 0 | Direct |
| dUTPase-like | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| N-terminal domain of DnaB helicase | 0 | Direct |
| Viral glycoprotein, central and dimerisation domains | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| Positive stranded ssRNA viruses | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Translation proteins | 0 | Direct |
| Nudix | 0 | Direct |
| Origin of replication-binding domain, RBD-like | 0 | Direct |
| Nucleic acid-binding proteins | 0 | Direct |
| P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
| Initiation factor IF2/eIF5b, domain 3 | 0 | Direct |
| C-terminal domain of Ku80 | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| EndoU-like | 0 | Direct |
| DHH phosphoesterases | 0 | Direct |
| mRNA decapping enzyme DcpS N-terminal domain | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| "Winged helix" DNA-binding domain | 0 | Direct |
| Acylphosphatase/BLUF domain-like | 0 | Direct |
| DNA helicase RuvA subunit, C-terminal domain | 0 | Direct |
| Apyrase | 0 | Direct |
| Dcp2 domain-like | 0 | Direct |
| Inorganic pyrophosphatase | 0 | Direct |
| ITPase-like | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Viral leader polypeptide zinc finger | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| all-alpha NTP pyrophosphatases | 0 | Direct |
| DNA primase core | 0 | Direct |
| Trypsin-like serine proteases | 0.00000000000001978 | Direct |
| vWA-like | 0.0000000000001217 | Direct |
| Tudor/PWWP/MBT | 0.00000000005312 | Direct |
| HMA, heavy metal-associated domain | 0.0000000002445 | Direct |
| SAP domain | 0.000000005555 | Direct |
| Coronavirus NSP10-like | 0.00000001137 | Direct |
| Replicase NSP9 | 0.00000001137 | Direct |
| Coronavirus NSP7-like | 0.00000001137 | Direct |
| Coronavirus NSP8-like | 0.00000001137 | Direct |
| Prokaryotic type I DNA topoisomerase | 0.00000001573 | Direct |
| MIT domain | 0.00000002557 | Direct |
| E set domains | 0.00000005792 | Direct |
| Homing endonucleases | 0.0000002295 | Direct |
| HRDC-like | 0.000000844 | Direct |
| Hedgehog/intein (Hint) domain | 0.000001163 | Direct |
| NSP3A-like | 0.000006227 | Direct |
| F-box domain | 0.00001555 | Direct |
| RNA-binding domain, RBD | 0.00005837 | Direct |
| Somatomedin B domain | 0.0000765 | Direct |
| FYVE/PHD zinc finger | 0.0002089 | Direct |
| R3H domain | 0.0004584 | Direct |
| CYTH-like phosphatases | 0.001704 | Inherited |
| Bromodomain | 0.001727 | Inherited |
| His-Me finger endonucleases | 0.001743 | Inherited |
| post-AAA+ oligomerization domain-like | 0.002681 | Inherited |
| Ankyrin repeat | 0.003305 | Inherited |
| WW domain | 0.00938 | Inherited |
| SARS Nsp1-like | 0.01206 | Inherited |
| Ribonuclease Rh-like | 0.0149 | Inherited |
| CCCH zinc finger | 0.05626 | Inherited |
| 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0.06675 | Inherited |
| Retrovirus zinc finger-like domains | 0.1082 | Inherited |
| ADC-like | 0.1534 | Inherited |
| HD-domain/PDEase-like | 0.1802 | Inherited |
| UBA-like | 0.193 | Inherited |
| Calcium ATPase, transduction domain A | 0.209 | Inherited |
| Calcium ATPase, transmembrane domain M | 0.212 | Inherited |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0.2558 | Inherited |
| NTF2-like | 0.2653 | Inherited |
| Actin-like ATPase domain | 0.4244 | Inherited |
| Retrovirus capsid dimerization domain-like | 0.58 | Inherited |
| Clavaminate synthase-like | 0.5909 | Inherited |
| HisI-like | 0.7063 | Inherited |
| Retrovirus capsid protein, N-terminal core domain | 0.8755 | Inherited |
| N-terminal Zn binding domain of HIV integrase | 0.9067 | Inherited |
| DNA-binding domain of retroviral integrase | 0.9283 | Inherited |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | Inherited |
| PH domain-like | 1 | Inherited |
| Cysteine proteinases | 1 | Inherited |
| SurE-like | 1 | Inherited |
| Ribonuclease H-like | 1 | Inherited |
| Acid proteases | 1 | Inherited |
| Alkaline phosphatase-like | 1 | Inherited |
| Macro domain-like | 1 | Inherited |
| S-adenosyl-L-methionine-dependent methyltransferases | 1 | Inherited |
| Retroviral matrix proteins | 1 | Inherited |
| HAD-like | 1 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Duplex) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | DIRECT |
52540,48403
52540 - P-loop containing nucleoside triphosphate hydrolases
48403 - Ankyrin repeat | 0 | DIRECT |
52540,49899
52540 - P-loop containing nucleoside triphosphate hydrolases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
141734,101386
141734 - HisI-like
101386 - all-alpha NTP pyrophosphatases | 0 | DIRECT |
52540,56672
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | DIRECT |
50249,52540
50249 - Nucleic acid-binding proteins
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
50494,52540
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,89043
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
50494,56672
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases | 0 | DIRECT |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
47781,46929
47781 - RuvA domain 2-like
46929 - DNA helicase RuvA subunit, C-terminal domain | 0 | DIRECT |
54585,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,54928
52540 - P-loop containing nucleoside triphosphate hydrolases
54928 - RNA-binding domain, RBD | 0 | DIRECT |
88633,50494
88633 - Positive stranded ssRNA viruses
50494 - Trypsin-like serine proteases | 0 | DIRECT |
55811,55811
55811 - Nudix
55811 - Nudix | 0 | DIRECT |
56983,81296
56983 - Viral glycoprotein, central and dimerisation domains
81296 - E set domains | 0 | DIRECT |
53335,52949
53335 - S-adenosyl-L-methionine-dependent methyltransferases
52949 - Macro domain-like | 0 | DIRECT |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
100939,68906
100939 - SPOC domain-like
68906 - SAP domain | 0 | DIRECT |
46785,47819
46785 - "Winged helix" DNA-binding domain
47819 - HRDC-like | 0 | DIRECT |
50916,46785
50916 - Rap30/74 interaction domains
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
56672,88633
56672 - DNA/RNA polymerases
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
48024,52540
48024 - N-terminal domain of DnaB helicase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
158702,52540
158702 - Sec63 N-terminal domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54980,54980
54980 - EF-G C-terminal domain-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
52156,50447
52156 - Initiation factor IF2/eIF5b, domain 3
50447 - Translation proteins | 0 | DIRECT |
53335,56672
53335 - S-adenosyl-L-methionine-dependent methyltransferases
56672 - DNA/RNA polymerases | 0 | DIRECT |
102860,54197
102860 - mRNA decapping enzyme DcpS N-terminal domain
54197 - HIT-like | 0 | DIRECT |
52540,-9
52540 - P-loop containing nucleoside triphosphate hydrolases
-9 - PDB | 0 | DIRECT |
50249,47781
50249 - Nucleic acid-binding proteins
47781 - RuvA domain 2-like | 0 | DIRECT |
52540,47819
52540 - P-loop containing nucleoside triphosphate hydrolases
47819 - HRDC-like | 0 | DIRECT |
55464,52540
55464 - Origin of replication-binding domain, RBD-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
101386,101386
101386 - all-alpha NTP pyrophosphatases
101386 - all-alpha NTP pyrophosphatases | 0 | DIRECT |
46785,158702
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like | 0 | DIRECT |
101386,53720
101386 - all-alpha NTP pyrophosphatases
53720 - ALDH-like | 0 | DIRECT |
56731,52540
56731 - DNA primase core
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51283,51283
51283 - dUTPase-like
51283 - dUTPase-like | 0 | DIRECT |
52540,-8
52540 - P-loop containing nucleoside triphosphate hydrolases
-8 - ECOD | 0 | DIRECT |
-9,52540
-9 - PDB
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
88633,88633
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
52540,56712
52540 - P-loop containing nucleoside triphosphate hydrolases
56712 - Prokaryotic type I DNA topoisomerase | 0 | DIRECT |
158702,81296
158702 - Sec63 N-terminal domain-like
81296 - E set domains | 0 | DIRECT |
55608,56712
55608 - Homing endonucleases
56712 - Prokaryotic type I DNA topoisomerase | 0 | DIRECT |
52980,47781
52980 - Restriction endonuclease-like
47781 - RuvA domain 2-like | 0 | DIRECT |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0 | DIRECT |
53335,142877
53335 - S-adenosyl-L-methionine-dependent methyltransferases
142877 - EndoU-like | 0 | DIRECT |
89043,50494
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases | 0 | DIRECT |
116846,52540
116846 - MIT domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
56672,52540
56672 - DNA/RNA polymerases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53067,109604
53067 - Actin-like ATPase domain
109604 - HD-domain/PDEase-like | 0 | DIRECT |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | DIRECT |
140586,55811
140586 - Dcp2 domain-like
55811 - Nudix | 0 | DIRECT |
54001,88633
54001 - Cysteine proteinases
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
52540,57756
52540 - P-loop containing nucleoside triphosphate hydrolases
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
52540,47370
52540 - P-loop containing nucleoside triphosphate hydrolases
47370 - Bromodomain | 0 | DIRECT |
52540,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
52540,52156
52540 - P-loop containing nucleoside triphosphate hydrolases
52156 - Initiation factor IF2/eIF5b, domain 3 | 0 | DIRECT |
160481,160481
160481 - BRK domain-like
160481 - BRK domain-like | 0 | DIRECT |
52540,142877
52540 - P-loop containing nucleoside triphosphate hydrolases
142877 - EndoU-like | 0 | DIRECT |
100939,101420
100939 - SPOC domain-like
101420 - C-terminal domain of Ku80 | 0 | DIRECT |
53300,100939
53300 - vWA-like
100939 - SPOC domain-like | 0 | DIRECT |
49899,52540
49899 - Concanavalin A-like lectins/glucanases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,51294
52540 - P-loop containing nucleoside triphosphate hydrolases
51294 - Hedgehog/intein (Hint) domain | 0.0000000000003508 | DIRECT |
48403,52540
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.00000000001872 | DIRECT |
57756,51283
57756 - Retrovirus zinc finger-like domains
51283 - dUTPase-like | 0.00000000004607 | DIRECT |
51283,50630
51283 - dUTPase-like
50630 - Acid proteases | 0.00000000004607 | DIRECT |
51197,52540
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.00000000007906 | DIRECT |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0.000000005555 | DIRECT |
143076,101816
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9 | 0.00000001137 | DIRECT |
140367,143076
140367 - Coronavirus NSP7-like
143076 - Coronavirus NSP8-like | 0.00000001137 | DIRECT |
101816,144246
101816 - Replicase NSP9
144246 - Coronavirus NSP10-like | 0.00000001137 | DIRECT |
51294,55608
51294 - Hedgehog/intein (Hint) domain
55608 - Homing endonucleases | 0.00000003829 | DIRECT |
56712,51294
56712 - Prokaryotic type I DNA topoisomerase
51294 - Hedgehog/intein (Hint) domain | 0.000003274 | DIRECT |
53649,54060
53649 - Alkaline phosphatase-like
54060 - His-Me finger endonucleases | 0.000005345 | DIRECT |
90188,53649
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0.0000765 | DIRECT |
90188,90188
90188 - Somatomedin B domain
90188 - Somatomedin B domain | 0.0000765 | DIRECT |
53098,51283
53098 - Ribonuclease H-like
51283 - dUTPase-like | 0.0000765 | DIRECT |
51283,46919
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase | 0.0000765 | DIRECT |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0.00009518 | DIRECT |
55608,52540
55608 - Homing endonucleases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.0001909 | DIRECT |
56672,46919
56672 - DNA/RNA polymerases
46919 - N-terminal Zn binding domain of HIV integrase | 0.001909 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
-8,52540
-8 - ECOD
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.001909 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement || RNA helicase |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0.002681 | INHERITED FROM: In phosphorus-containing anhydrides || Adenosinetriphosphatase |
159936,52949
159936 - NSP3A-like
52949 - Macro domain-like | 0.01206 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement || DNA helicase || RNA helicase |
159936,53335
159936 - NSP3A-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0.01958 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement || DNA helicase || RNA helicase |
56300,55816
56300 - Metallo-dependent phosphatases
55816 - 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0.06675 | INHERITED FROM: UDP-sugar diphosphatase || In phosphorus-containing anhydrides || Apyrase |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.2644 | INHERITED FROM: Acting on acid anhydrides; catalyzing transmembrane movement of substances |
47943,47353
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like | 0.58 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
46919,53098
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0.9067 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
53098,50122
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0.9283 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
47353,57756
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains | 0.9828 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
56672,53098
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like | 1 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
50630,56672
50630 - Acid proteases
56672 - DNA/RNA polymerases | 1 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
57756,50630
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 1 | INHERITED FROM: dUTP diphosphatase |
53098,46919
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase | 1 | INHERITED FROM: dUTP diphosphatase |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | Direct |
52540,48403
52540 - P-loop containing nucleoside triphosphate hydrolases
48403 - Ankyrin repeat | 0 | Direct |
52540,49899
52540 - P-loop containing nucleoside triphosphate hydrolases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
141734,101386
141734 - HisI-like
101386 - all-alpha NTP pyrophosphatases | 0 | Direct |
52540,56672
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | Direct |
50249,52540
50249 - Nucleic acid-binding proteins
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
50494,52540
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,89043
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a | 0 | Direct |
50494,56672
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases | 0 | Direct |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
47781,46929
47781 - RuvA domain 2-like
46929 - DNA helicase RuvA subunit, C-terminal domain | 0 | Direct |
54585,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,54928
52540 - P-loop containing nucleoside triphosphate hydrolases
54928 - RNA-binding domain, RBD | 0 | Direct |
88633,50494
88633 - Positive stranded ssRNA viruses
50494 - Trypsin-like serine proteases | 0 | Direct |
55811,55811
55811 - Nudix
55811 - Nudix | 0 | Direct |
56983,81296
56983 - Viral glycoprotein, central and dimerisation domains
81296 - E set domains | 0 | Direct |
53335,52949
53335 - S-adenosyl-L-methionine-dependent methyltransferases
52949 - Macro domain-like | 0 | Direct |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
100939,68906
100939 - SPOC domain-like
68906 - SAP domain | 0 | Direct |
46785,47819
46785 - "Winged helix" DNA-binding domain
47819 - HRDC-like | 0 | Direct |
50916,46785
50916 - Rap30/74 interaction domains
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
56672,88633
56672 - DNA/RNA polymerases
88633 - Positive stranded ssRNA viruses | 0 | Direct |
48024,52540
48024 - N-terminal domain of DnaB helicase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
158702,52540
158702 - Sec63 N-terminal domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54980,54980
54980 - EF-G C-terminal domain-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
52156,50447
52156 - Initiation factor IF2/eIF5b, domain 3
50447 - Translation proteins | 0 | Direct |
53335,56672
53335 - S-adenosyl-L-methionine-dependent methyltransferases
56672 - DNA/RNA polymerases | 0 | Direct |
102860,54197
102860 - mRNA decapping enzyme DcpS N-terminal domain
54197 - HIT-like | 0 | Direct |
52540,-9
52540 - P-loop containing nucleoside triphosphate hydrolases
-9 - PDB | 0 | Direct |
50249,47781
50249 - Nucleic acid-binding proteins
47781 - RuvA domain 2-like | 0 | Direct |
52540,47819
52540 - P-loop containing nucleoside triphosphate hydrolases
47819 - HRDC-like | 0 | Direct |
55464,52540
55464 - Origin of replication-binding domain, RBD-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
101386,101386
101386 - all-alpha NTP pyrophosphatases
101386 - all-alpha NTP pyrophosphatases | 0 | Direct |
46785,158702
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like | 0 | Direct |
101386,53720
101386 - all-alpha NTP pyrophosphatases
53720 - ALDH-like | 0 | Direct |
56731,52540
56731 - DNA primase core
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51283,51283
51283 - dUTPase-like
51283 - dUTPase-like | 0 | Direct |
52540,-8
52540 - P-loop containing nucleoside triphosphate hydrolases
-8 - ECOD | 0 | Direct |
-9,52540
-9 - PDB
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
88633,88633
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | Direct |
52540,56712
52540 - P-loop containing nucleoside triphosphate hydrolases
56712 - Prokaryotic type I DNA topoisomerase | 0 | Direct |
158702,81296
158702 - Sec63 N-terminal domain-like
81296 - E set domains | 0 | Direct |
55608,56712
55608 - Homing endonucleases
56712 - Prokaryotic type I DNA topoisomerase | 0 | Direct |
52980,47781
52980 - Restriction endonuclease-like
47781 - RuvA domain 2-like | 0 | Direct |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0 | Direct |
53335,142877
53335 - S-adenosyl-L-methionine-dependent methyltransferases
142877 - EndoU-like | 0 | Direct |
89043,50494
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases | 0 | Direct |
116846,52540
116846 - MIT domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
56672,52540
56672 - DNA/RNA polymerases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53067,109604
53067 - Actin-like ATPase domain
109604 - HD-domain/PDEase-like | 0 | Direct |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | Direct |
140586,55811
140586 - Dcp2 domain-like
55811 - Nudix | 0 | Direct |
54001,88633
54001 - Cysteine proteinases
88633 - Positive stranded ssRNA viruses | 0 | Direct |
52540,57756
52540 - P-loop containing nucleoside triphosphate hydrolases
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
52540,47370
52540 - P-loop containing nucleoside triphosphate hydrolases
47370 - Bromodomain | 0 | Direct |
52540,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
54980 - EF-G C-terminal domain-like | 0 | Direct |
52540,52156
52540 - P-loop containing nucleoside triphosphate hydrolases
52156 - Initiation factor IF2/eIF5b, domain 3 | 0 | Direct |
160481,160481
160481 - BRK domain-like
160481 - BRK domain-like | 0 | Direct |
52540,142877
52540 - P-loop containing nucleoside triphosphate hydrolases
142877 - EndoU-like | 0 | Direct |
100939,101420
100939 - SPOC domain-like
101420 - C-terminal domain of Ku80 | 0 | Direct |
53300,100939
53300 - vWA-like
100939 - SPOC domain-like | 0 | Direct |
49899,52540
49899 - Concanavalin A-like lectins/glucanases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,51294
52540 - P-loop containing nucleoside triphosphate hydrolases
51294 - Hedgehog/intein (Hint) domain | 0.0000000000003508 | Direct |
48403,52540
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.00000000001872 | Direct |
57756,51283
57756 - Retrovirus zinc finger-like domains
51283 - dUTPase-like | 0.00000000004607 | Direct |
51283,50630
51283 - dUTPase-like
50630 - Acid proteases | 0.00000000004607 | Direct |
51197,52540
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.00000000007906 | Direct |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0.000000005555 | Direct |
143076,101816
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9 | 0.00000001137 | Direct |
140367,143076
140367 - Coronavirus NSP7-like
143076 - Coronavirus NSP8-like | 0.00000001137 | Direct |
101816,144246
101816 - Replicase NSP9
144246 - Coronavirus NSP10-like | 0.00000001137 | Direct |
51294,55608
51294 - Hedgehog/intein (Hint) domain
55608 - Homing endonucleases | 0.00000003829 | Direct |
56712,51294
56712 - Prokaryotic type I DNA topoisomerase
51294 - Hedgehog/intein (Hint) domain | 0.000003274 | Direct |
53649,54060
53649 - Alkaline phosphatase-like
54060 - His-Me finger endonucleases | 0.000005345 | Direct |
90188,53649
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0.0000765 | Direct |
90188,90188
90188 - Somatomedin B domain
90188 - Somatomedin B domain | 0.0000765 | Direct |
53098,51283
53098 - Ribonuclease H-like
51283 - dUTPase-like | 0.0000765 | Direct |
51283,46919
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase | 0.0000765 | Direct |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0.00009518 | Direct |
55608,52540
55608 - Homing endonucleases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.0001909 | Direct |
56672,46919
56672 - DNA/RNA polymerases
46919 - N-terminal Zn binding domain of HIV integrase | 0.001909 | Inherited |
-8,52540
-8 - ECOD
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.001909 | Inherited |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0.002681 | Inherited |
159936,52949
159936 - NSP3A-like
52949 - Macro domain-like | 0.01206 | Inherited |
159936,53335
159936 - NSP3A-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0.01958 | Inherited |
56300,55816
56300 - Metallo-dependent phosphatases
55816 - 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0.06675 | Inherited |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.2644 | Inherited |
47943,47353
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like | 0.58 | Inherited |
46919,53098
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0.9067 | Inherited |
53098,50122
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0.9283 | Inherited |
47353,57756
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains | 0.9828 | Inherited |
56672,53098
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like | 1 | Inherited |
50630,56672
50630 - Acid proteases
56672 - DNA/RNA polymerases | 1 | Inherited |
57756,50630
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 1 | Inherited |
53098,46919
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase | 1 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Triple) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
141734,101386,53720
141734 - HisI-like
101386 - all-alpha NTP pyrophosphatases
53720 - ALDH-like | 0 | DIRECT |
52540,52540,47370
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
47370 - Bromodomain | 0 | DIRECT |
50494,52540,52540
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54585,52540,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50249,52540,52540
50249 - Nucleic acid-binding proteins
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50630,56672,46919
50630 - Acid proteases
56672 - DNA/RNA polymerases
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
46785,158702,81296
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like
81296 - E set domains | 0 | DIRECT |
52540,52540,56672
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | DIRECT |
53300,100939,101420
53300 - vWA-like
100939 - SPOC domain-like
101420 - C-terminal domain of Ku80 | 0 | DIRECT |
52540,52540,56712
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
56712 - Prokaryotic type I DNA topoisomerase | 0 | DIRECT |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,52540,47819
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
47819 - HRDC-like | 0 | DIRECT |
50692,54585,52540
50692 - ADC-like
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,52156,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
52156 - Initiation factor IF2/eIF5b, domain 3
50447 - Translation proteins | 0 | DIRECT |
52540,48403,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
52540,54980,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
54980 - EF-G C-terminal domain-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
52540,46785,47819
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain
47819 - HRDC-like | 0 | DIRECT |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
89043,50494,56672
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases | 0 | DIRECT |
50494,56672,88633
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
53067,53067,109604
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
109604 - HD-domain/PDEase-like | 0 | DIRECT |
48024,52540,51294
48024 - N-terminal domain of DnaB helicase
52540 - P-loop containing nucleoside triphosphate hydrolases
51294 - Hedgehog/intein (Hint) domain | 0 | DIRECT |
51197,52540,56672
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | DIRECT |
88633,50494,52540
88633 - Positive stranded ssRNA viruses
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
158702,52540,52540
158702 - Sec63 N-terminal domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
46785,158702,52540
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50494,52540,56672
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | DIRECT |
56672,52540,52540
56672 - DNA/RNA polymerases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,52540,142877
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
142877 - EndoU-like | 0 | DIRECT |
51197,52540,52540
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,46785,158702
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like | 0 | DIRECT |
88633,88633,88633
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
52540,89043,50494
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases | 0 | DIRECT |
53300,100939,68906
53300 - vWA-like
100939 - SPOC domain-like
68906 - SAP domain | 0 | DIRECT |
50494,52540,89043
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
52540,56712,51294
52540 - P-loop containing nucleoside triphosphate hydrolases
56712 - Prokaryotic type I DNA topoisomerase
51294 - Hedgehog/intein (Hint) domain | 0 | DIRECT |
52540,49899,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
49899 - Concanavalin A-like lectins/glucanases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50249,47781,46929
50249 - Nucleic acid-binding proteins
47781 - RuvA domain 2-like
46929 - DNA helicase RuvA subunit, C-terminal domain | 0 | DIRECT |
54001,88633,88633
54001 - Cysteine proteinases
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
50447,54980,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
57756,51283,50630
57756 - Retrovirus zinc finger-like domains
51283 - dUTPase-like
50630 - Acid proteases | 0.00000000004607 | DIRECT |
140367,143076,101816
140367 - Coronavirus NSP7-like
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9 | 0.00000001137 | DIRECT |
143076,101816,144246
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9
144246 - Coronavirus NSP10-like | 0.00000001137 | DIRECT |
52540,51294,55608
52540 - P-loop containing nucleoside triphosphate hydrolases
51294 - Hedgehog/intein (Hint) domain
55608 - Homing endonucleases | 0.00000006142 | DIRECT |
57756,57756,51283
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains
51283 - dUTPase-like | 0.0000006664 | DIRECT |
47353,57756,57756
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0.0000006664 | DIRECT |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.000003274 | DIRECT |
51283,50630,56672
51283 - dUTPase-like
50630 - Acid proteases
56672 - DNA/RNA polymerases | 0.000003281 | DIRECT |
90188,53649,54060
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like
54060 - His-Me finger endonucleases | 0.000005345 | DIRECT |
90188,90188,53649
90188 - Somatomedin B domain
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0.0000765 | DIRECT |
53098,51283,46919
53098 - Ribonuclease H-like
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase | 0.0000765 | DIRECT |
51283,46919,53098
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0.0000765 | DIRECT |
56672,53098,51283
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
51283 - dUTPase-like | 0.0000765 | DIRECT |
56672,46919,53098
56672 - DNA/RNA polymerases
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0.001909 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
46919,53098,50122
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0.8824 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
47943,47353,57756
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains | 0.9828 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
53098,46919,53098
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 1 | INHERITED FROM: dUTP diphosphatase |
50630,56672,53098
50630 - Acid proteases
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like | 1 | INHERITED FROM: dUTP diphosphatase || In phosphorus-containing anhydrides |
56672,53098,46919
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase | 1 | INHERITED FROM: dUTP diphosphatase |
57756,50630,56672
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases
56672 - DNA/RNA polymerases | 1 | INHERITED FROM: dUTP diphosphatase |
47353,57756,50630
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 1 | INHERITED FROM: dUTP diphosphatase |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
141734,101386,53720
141734 - HisI-like
101386 - all-alpha NTP pyrophosphatases
53720 - ALDH-like | 0 | Direct |
52540,52540,47370
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
47370 - Bromodomain | 0 | Direct |
50494,52540,52540
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54585,52540,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50249,52540,52540
50249 - Nucleic acid-binding proteins
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50630,56672,46919
50630 - Acid proteases
56672 - DNA/RNA polymerases
46919 - N-terminal Zn binding domain of HIV integrase | 0 | Direct |
46785,158702,81296
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like
81296 - E set domains | 0 | Direct |
52540,52540,56672
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | Direct |
53300,100939,101420
53300 - vWA-like
100939 - SPOC domain-like
101420 - C-terminal domain of Ku80 | 0 | Direct |
52540,52540,56712
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
56712 - Prokaryotic type I DNA topoisomerase | 0 | Direct |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,52540,47819
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
47819 - HRDC-like | 0 | Direct |
50692,54585,52540
50692 - ADC-like
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,52156,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
52156 - Initiation factor IF2/eIF5b, domain 3
50447 - Translation proteins | 0 | Direct |
52540,48403,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
52540,54980,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
54980 - EF-G C-terminal domain-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
52540,46785,47819
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain
47819 - HRDC-like | 0 | Direct |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
89043,50494,56672
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases | 0 | Direct |
50494,56672,88633
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases
88633 - Positive stranded ssRNA viruses | 0 | Direct |
53067,53067,109604
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
109604 - HD-domain/PDEase-like | 0 | Direct |
48024,52540,51294
48024 - N-terminal domain of DnaB helicase
52540 - P-loop containing nucleoside triphosphate hydrolases
51294 - Hedgehog/intein (Hint) domain | 0 | Direct |
51197,52540,56672
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | Direct |
88633,50494,52540
88633 - Positive stranded ssRNA viruses
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
158702,52540,52540
158702 - Sec63 N-terminal domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
46785,158702,52540
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50494,52540,56672
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | Direct |
56672,52540,52540
56672 - DNA/RNA polymerases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,52540,142877
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
142877 - EndoU-like | 0 | Direct |
51197,52540,52540
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,46785,158702
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like | 0 | Direct |
88633,88633,88633
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | Direct |
52540,89043,50494
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases | 0 | Direct |
53300,100939,68906
53300 - vWA-like
100939 - SPOC domain-like
68906 - SAP domain | 0 | Direct |
50494,52540,89043
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a | 0 | Direct |
52540,56712,51294
52540 - P-loop containing nucleoside triphosphate hydrolases
56712 - Prokaryotic type I DNA topoisomerase
51294 - Hedgehog/intein (Hint) domain | 0 | Direct |
52540,49899,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
49899 - Concanavalin A-like lectins/glucanases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50249,47781,46929
50249 - Nucleic acid-binding proteins
47781 - RuvA domain 2-like
46929 - DNA helicase RuvA subunit, C-terminal domain | 0 | Direct |
54001,88633,88633
54001 - Cysteine proteinases
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | Direct |
50447,54980,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
57756,51283,50630
57756 - Retrovirus zinc finger-like domains
51283 - dUTPase-like
50630 - Acid proteases | 0.00000000004607 | Direct |
140367,143076,101816
140367 - Coronavirus NSP7-like
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9 | 0.00000001137 | Direct |
143076,101816,144246
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9
144246 - Coronavirus NSP10-like | 0.00000001137 | Direct |
52540,51294,55608
52540 - P-loop containing nucleoside triphosphate hydrolases
51294 - Hedgehog/intein (Hint) domain
55608 - Homing endonucleases | 0.00000006142 | Direct |
57756,57756,51283
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains
51283 - dUTPase-like | 0.0000006664 | Direct |
47353,57756,57756
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0.0000006664 | Direct |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.000003274 | Direct |
51283,50630,56672
51283 - dUTPase-like
50630 - Acid proteases
56672 - DNA/RNA polymerases | 0.000003281 | Direct |
90188,53649,54060
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like
54060 - His-Me finger endonucleases | 0.000005345 | Direct |
90188,90188,53649
90188 - Somatomedin B domain
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0.0000765 | Direct |
53098,51283,46919
53098 - Ribonuclease H-like
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase | 0.0000765 | Direct |
51283,46919,53098
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0.0000765 | Direct |
56672,53098,51283
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
51283 - dUTPase-like | 0.0000765 | Direct |
56672,46919,53098
56672 - DNA/RNA polymerases
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0.001909 | Inherited |
46919,53098,50122
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0.8824 | Inherited |
47943,47353,57756
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains | 0.9828 | Inherited |
53098,46919,53098
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 1 | Inherited |
50630,56672,53098
50630 - Acid proteases
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like | 1 | Inherited |
56672,53098,46919
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase | 1 | Inherited |
57756,50630,56672
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases
56672 - DNA/RNA polymerases | 1 | Inherited |
47353,57756,50630
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 1 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Plot distribution on species Tree Of Life (sTOL) for Superfamily and/or Family domains annotated by this EC term
 |
Plot tree as:
| |
Download Newick format tree:
|
( show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domain
architecture data for all genomes in SUPERFAMILY. The PAUP
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
Plot distribution on species Tree Of Life (sTOL) for single supra-domains annotated by this EC term
|
Plot tree as:
| |
Download Newick format tree:
| |
Browsing in TREE OF LIFE:
|
( show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
|
|
> BO Hierarchy > Acting on acid anhydrides
