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  Home > GO hierarchy > With NADH or NADPH as one donor, and incorporation

With NADH or NADPH as one donor, and incorporation

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Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   root [root] <6>
+ + 2:   Oxidoreductases [1] <23>(183|263) (202|169|83)
+ 1:   Acting on paired donors, with incorporation or red [1.14] <12>(35|37) (38|19|5)
0:   With NADH or NADPH as one donor, and incorporation [1.14.13] <156>(10|10) (12|6|2)
- 1:   (+)-abscisic acid 8'-hydroxylase [1.14.13.93](0|0) (0|0|0)
- 1:   (+)-menthofuran synthase [1.14.13.104](0|0) (0|0|0)
- 1:   (-)-menthol monooxygenase [1.14.13.46](0|0) (0|0|0)
- 1:   (R)-limonene 6-monooxygenase [1.14.13.80](0|0) (0|0|0)
- 1:   (S)-limonene 3-monooxygenase [1.14.13.47](0|0) (0|0|0)
- 1:   (S)-limonene 6-monooxygenase [1.14.13.48](0|0) (0|0|0)
- 1:   (S)-limonene 7-monooxygenase [1.14.13.49](0|0) (0|0|0)
- 1:   1-hydroxy-2-naphthoate hydroxylase [1.14.13.135](0|0) (0|0|0)
- 1:   2,4-dichlorophenol 6-monooxygenase [1.14.13.20](0|0) (0|0|0)
- 1:   2,6-dihydroxypyridine 3-monooxygenase [1.14.13.10](0|0) (0|0|0)
- 1:   2-hydroxy-1,4-benzoxazin-3-one monooxygenase [1.14.13.140](0|0) (0|0|0)
- 1:   2-hydroxybiphenyl 3-monooxygenase [1.14.13.44](0|0) (0|0|0)
- 1:   2-hydroxycyclohexanone 2-monooxygenase [1.14.13.66](0|0) (0|0|0)
- 1:   2-hydroxyisoflavanone synthase [1.14.13.86](0|0) (0|0|0)
- 1:   2-hydroxyquinoline 8-monooxygenase [1.14.13.61](0|0) (0|0|0)
- 1:   2-nitrophenol 2-monooxygenase [1.14.13.31](0|0) (0|0|0)
- 1:   24-hydroxycholesterol 7-alpha-hydroxylase [1.14.13.99](0|0) (0|0|0)
- 1:   25-hydroxycholesterol 7-alpha-hydroxylase [1.14.13.100](0|0) (0|0|0)
- 1:   27-hydroxycholesterol 7-alpha-monooxygenase [1.14.13.60](0|0) (0|0|0)
- 1:   3,9-dihydroxypterocarpan 6A-monooxygenase [1.14.13.28](0|0) (0|0|0)
- 1:   3-(3-hydroxy-phenyl)propanoic acid hydroxylase [1.14.13.127](1|1) (1|0|0)
- 1:   3-epi-6-deoxocathasterone 23-monooxygenase [1.14.13.112](0|0) (0|0|0)
- 1:   3-hydroxybenzoate 4-monooxygenase [1.14.13.23](0|0) (0|0|0)
- 1:   3-hydroxybenzoate 6-monooxygenase [1.14.13.24](1|1) (1|1|0)
- 1:   3-hydroxyindolin-2-one monooxygenase [1.14.13.139](0|0) (0|0|0)
- 1:   3-hydroxyphenylacetate 6-hydroxylase [1.14.13.63](0|0) (0|0|0)
- 1:   3-ketosteroid 9-alpha-monooxygenase [1.14.13.142](0|0) (0|0|0)
- 1:   4'-methoxyisoflavone 2'-hydroxylase [1.14.13.53](0|0) (0|0|0)
- 1:   4-aminobenzoate 1-monooxygenase [1.14.13.27](0|0) (0|0|0)
- 1:   4-hydroxyacetophenone monooxygenase [1.14.13.84](0|0) (0|0|0)
- 1:   4-hydroxybenzoate 1-hydroxylase [1.14.13.64](0|0) (0|0|0)
- 1:   4-hydroxybenzoate 3-monooxygenase [1.14.13.2](0|0) (1|1|0)
- 1:   4-hydroxybenzoate 3-monooxygenase (NAD(P)H) [1.14.13.33](0|0) (0|0|0)
- 1:   4-hydroxyphenylacetaldehyde oxime monooxygenase [1.14.13.68](0|0) (0|0|0)
- 1:   4-hydroxyphenylacetate 1-monooxygenase [1.14.13.18](0|0) (0|0|0)
- 1:   4-hydroxyquinoline 3-monooxygenase [1.14.13.62](0|0) (0|0|0)
- 1:   4-nitrophenol 2-hydroxylase [1.14.13.n7](0|0) (0|0|0)
- 1:   4-nitrophenol 2-monooxygenase [1.14.13.29](0|0) (0|0|0)
- 1:   5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase [1.14.13.36](0|0) (0|0|0)
- 1:   5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hy [1.14.13.96](0|0) (0|0|0)
- 1:   5-epiaristolochene 1,3-dihydroxylase [1.14.13.119](0|0) (0|0|0)
- 1:   6-hydroxynicotinate 3-monooxygenase [1.14.13.114](0|0) (0|0|0)
- 1:   6-oxocineole dehydrogenase [1.14.13.51](0|0) (0|0|0)
- 1:   7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxy [1.14.13.95](0|0) (0|0|0)
- 1:   7-deoxyloganin 7-hydroxylase [1.14.13.74](0|0) (0|0|0)
- 1:   7-methylxanthine demethylase [1.14.13.128](0|0) (0|0|0)
- 1:   8-dimethylallylnaringenin 2'-hydroxylase [1.14.13.103](0|0) (0|0|0)
- 1:   9-beta-pimara-7,15-diene oxidase [1.14.13.144](0|0) (0|0|0)
- 1:   Abieta-7,13-diene hydroxylase [1.14.13.108](0|0) (0|0|0)
- 1:   Abietadienol hydroxylase [1.14.13.109](0|0) (0|0|0)
- 1:   Albendazole monooxygenase [1.14.13.32](0|0) (0|0|0)
- 1:   Alkene monooxygenase [1.14.13.69](0|0) (0|0|0)
- 1:   Angelicin synthase [1.14.13.115](0|0) (0|0|0)
- 1:   Anhydrotetracycline monooxygenase [1.14.13.38](0|0) (0|0|0)
- 1:   Anthranilate 3-monooxygenase (deaminating) [1.14.13.35](0|0) (0|0|0)
- 1:   Anthraniloyl-CoA monooxygenase [1.14.13.40](0|0) (0|0|0)
- 1:   Benzoate 4-monooxygenase [1.14.13.12](0|0) (0|0|0)
- 1:   Benzoyl-CoA 3-monooxygenase [1.14.13.58](0|0) (0|0|0)
- 1:   Beta-amyrin 11-oxidase [1.14.13.134](0|0) (0|0|0)
- 1:   Beta-carotene 3-hydroxylase [1.14.13.129](0|0) (0|0|0)
- 1:   Calcidiol 1-monooxygenase [1.14.13.13](0|0) (0|0|0)
- 1:   Chlorophyllide-a oxygenase [1.14.13.122](0|0) (2|1|0)
- 1:   Cholest-4-en-3-one 26-monooxygenase [1.14.13.141](0|0) (0|0|0)
- 1:   Cholestanetriol 26-monooxygenase [1.14.13.15](0|0) (0|0|0)
- 1:   Cholesterol 24-hydroxylase [1.14.13.98](0|0) (0|0|0)
- 1:   Cholesterol 7-alpha-monooxygenase [1.14.13.17](0|0) (0|0|0)
- 1:   Costunolide synthase [1.14.13.120](0|0) (0|0|0)
- 1:   Cyclohexanone monooxygenase [1.14.13.22](0|0) (0|0|0)
- 1:   Cyclopentanone monooxygenase [1.14.13.16](0|0) (0|0|0)
- 1:   Deleted entry [1.14.13.42](0|0) (0|0|0)
- 1:   Deleted entry [1.14.13.65](0|0) (0|0|0)
- 1:   Deoxysarpagine hydroxylase [1.14.13.91](0|0) (0|0|0)
- 1:   Dihomomethionine N-hydroxylase [1.14.13.n5](0|0) (0|0|0)
- 1:   Dihydrochelirubine 12-monooxygenase [1.14.13.57](0|0) (0|0|0)
- 1:   Dihydrosanguinarine 10-monooxygenase [1.14.13.56](0|0) (0|0|0)
- 1:   Dimethyl-sulfide monooxygenase [1.14.13.131](0|0) (0|0|0)
- 1:   Ent-cassa-12,15-diene 11-hydroxylase [1.14.13.145](0|0) (0|0|0)
- 1:   Ent-isokaurene C2-hydroxylase [1.14.13.143](0|0) (0|0|0)
- 1:   Ent-kaurene oxidase [1.14.13.78](0|0) (0|0|0)
- 1:   Ent-kaurenoic acid oxidase [1.14.13.79](0|0) (0|0|0)
- 1:   Epi-isozizaene 5-monooxygenase [1.14.13.106](0|0) (0|0|0)
- 1:   FAD-dependent urate hydroxylase [1.14.13.113](0|0) (0|0|0)
- 1:   Flavin-containing monooxygenase [1.14.13.8](1|1) (1|1|0)
- 1:   Flavonoid 3',5'-hydroxylase [1.14.13.88](0|0) (0|0|0)
- 1:   Flavonoid 3'-monooxygenase [1.14.13.21](0|0) (0|0|0)
- 1:   Geranylgeraniol 18-hydroxylase [1.14.13.110](0|0) (0|0|0)
- 1:   Geranylhydroquinone 3''-hydroxylase [1.14.13.116](0|0) (0|0|0)
- 1:   Germacrene A hydroxylase [1.14.13.123](0|0) (0|0|0)
- 1:   Glyceollin synthase [1.14.13.85](0|0) (0|0|0)
- 1:   Hexahomomethionine N-hydroxylase [1.14.13.n6](0|0) (0|0|0)
- 1:   Imidazoleacetate 4-monooxygenase [1.14.13.5](0|0) (0|0|0)
- 1:   Indole-2-monooxygenase [1.14.13.137](0|0) (0|0|0)
- 1:   Indolin-2-one monooxygenase [1.14.13.138](0|0) (0|0|0)
- 1:   Isoflavone 2'-hydroxylase [1.14.13.89](0|0) (0|0|0)
- 1:   Isoflavone 3'-hydroxylase [1.14.13.52](0|0) (0|0|0)
- 1:   Isoflavonoid synthase [1.14.13.136](0|0) (0|0|0)
- 1:   Isoleucine N-monooxygenase [1.14.13.117](0|0) (0|0|0)
- 1:   Ketosteroid monooxygenase [1.14.13.54](0|0) (0|0|0)
- 1:   Kynurenine 3-monooxygenase [1.14.13.9](1|0) (1|0|0)
- 1:   L-lysine 6-monooxygenase (NADPH) [1.14.13.59](0|0) (0|1|0)
- 1:   Leukotriene-B(4) 20-monooxygenase [1.14.13.30](0|0) (0|0|0)
- 1:   Leukotriene-E(4) 20-monooxygenase [1.14.13.34](0|0) (0|0|0)
- 1:   Licodione synthase [1.14.13.87](0|0) (0|0|0)
- 1:   Limonene 1,2-monooxygenase [1.14.13.107](0|0) (0|0|0)
- 1:   Lithocholate 6-beta-hydroxylase [1.14.13.94](0|0) (0|0|0)
- 1:   Magnesium-protoporphyrin IX monomethyl ester (oxid [1.14.13.81](1|0) (1|0|0)
- 1:   Melilotate 3-monooxygenase [1.14.13.4](0|0) (0|0|0)
- 1:   Methane monooxygenase (soluble) [1.14.13.25](0|0) (0|0|0)
- 1:   Methanesulfonate monooxygenase [1.14.13.111](0|0) (0|0|0)
- 1:   Methylsterol monooxygenase [1.14.13.72](0|0) (0|0|0)
- 1:   Methyltetrahydroprotoberberine 14-monooxygenase [1.14.13.37](0|0) (0|0|0)
- 1:   Monocyclic monoterpene ketone monooxygenase [1.14.13.105](0|0) (0|0|0)
- 1:   N-methylcoclaurine 3'-monooxygenase [1.14.13.71](0|0) (0|0|0)
- 1:   Nitric-oxide synthase [1.14.13.39](5|5) (5|2|1)
- 1:   Orcinol 2-monooxygenase [1.14.13.6](0|0) (0|0|0)
- 1:   Pentachlorophenol monooxygenase [1.14.13.50](0|0) (0|0|0)
- 1:   Pentalenene oxygenase [1.14.13.133](0|0) (0|0|0)
- 1:   Phenol 2-monooxygenase [1.14.13.7](0|0) (0|0|0)
- 1:   Phenylacetone monooxygenase [1.14.13.92](0|0) (0|0|0)
- 1:   Phenylacetyl-CoA 1,2-epoxidase [1.14.13.149](0|0) (0|0|0)
- 1:   Phenylalanine N-monooxygenase [1.14.13.124](0|0) (0|0|0)
- 1:   Phosphatidylcholine 12-monooxygenase [1.14.13.26](0|0) (0|0|0)
- 1:   Precorrin-3B synthase [1.14.13.83](0|0) (0|0|0)
- 1:   Premnaspirodiene oxygenase [1.14.13.121](0|0) (0|0|0)
- 1:   Protopine 6-monooxygenase [1.14.13.55](0|0) (0|0|0)
- 1:   Psoralen synthase [1.14.13.102](0|0) (0|0|0)
- 1:   Pyrrole-2-carboxylate monooxygenase [1.14.13.130](0|0) (0|0|0)
- 1:   Questin monooxygenase [1.14.13.43](0|0) (0|0|0)
- 1:   Quinine 3-monooxygenase [1.14.13.67](0|0) (0|0|0)
- 1:   Salicylate 1-monooxygenase [1.14.13.1](0|0) (0|0|0)
- 1:   Senecionine N-oxygenase [1.14.13.101](0|0) (0|0|0)
- 1:   Squalene monooxygenase [1.14.13.132](1|0) (1|0|0)
- 1:   Sterol 14-demethylase [1.14.13.70](1|1) (1|0|0)
- 1:   Tabersonine 16-hydroxylase [1.14.13.73](0|0) (0|0|0)
- 1:   Taurochenodeoxycholate 6-alpha-hydroxylase [1.14.13.97](0|0) (0|0|0)
- 1:   Taxane 10-beta-hydroxylase [1.14.13.76](0|0) (0|0|0)
- 1:   Taxane 13-alpha-hydroxylase [1.14.13.77](0|0) (0|0|0)
- 1:   Taxifolin 8-monooxygenase [1.14.13.19](0|0) (0|0|0)
- 1:   Taxoid 14-beta-hydroxylase [1.14.13.146](0|0) (0|0|0)
- 1:   Taxoid 7-beta-hydroxylase [1.14.13.147](0|0) (0|0|0)
- 1:   Trans-cinnamate 2-monooxygenase [1.14.13.14](0|0) (0|0|0)
- 1:   Trans-cinnamate 4-monooxygenase [1.14.13.11](1|0) (1|0|0)
- 1:   Transferred entry: 1.14.13.124 [1.14.13.n1](0|0) (0|0|0)
- 1:   Transferred entry: 1.14.13.125 [1.14.13.n2](0|0) (0|0|0)
- 1:   Transferred entry: 1.14.13.126 [1.14.13.n4](0|0) (0|0|0)
- 1:   Transferred entry: 1.14.13.127 [1.14.13.n3](0|0) (0|0|0)
- 1:   Transferred entry: 1.14.14.9 [1.14.13.3](0|0) (0|0|0)
- 1:   Transferred entry: 1.14.18.2 [1.14.13.45](0|0) (0|0|0)
- 1:   Trimethylamine monooxygenase [1.14.13.148](0|0) (0|1|0)
- 1:   Tryptophan N-monooxygenase [1.14.13.125](0|0) (0|0|0)
- 1:   Tyrosine N-monooxygenase [1.14.13.41](0|0) (0|0|0)
- 1:   Valine N-monooxygenase [1.14.13.118](0|0) (0|0|0)
- 1:   Vanillate monooxygenase [1.14.13.82](0|0) (0|0|0)
- 1:   Vinorine hydroxylase [1.14.13.75](0|0) (0|0|0)
- 1:   Vitamin D(3) 24-hydroxylase [1.14.13.126](0|0) (0|0|0)
- 1:   Zeaxanthin epoxidase [1.14.13.90](1|2) (1|0|0)

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Superfamily

(show details)
SCOP term FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
FAD/NAD(P)-binding domain0Direct
SMAD/FHA domain0.000000000001841Direct
Flavoproteins0.000000000003249Direct
FAD-linked reductases, C-terminal domain0.0000000007149Direct
Ferritin-like0.000000003244Direct
PDZ domain-like0.0000003399Direct
Cytochrome P4500.02235Inherited
Riboflavin synthase domain-like0.06286Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.1139Inherited

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Family

(show details)
SCOP term FDR (all) Annotation (direct or inherited)
PHBH-like0Direct
FAD/NAD-linked reductases, N-terminal and central domains0Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
FAD-linked reductases, N-terminal domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
FHA domain0.0000000000001689Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.000000000000602Direct
PDZ domain0.0000000000009221Direct
NADPH-cytochrome p450 reductase-like0.000000000006862Direct
Cytochrome P4500.0003169Direct

Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this EC term
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Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
FAD/NAD(P)-binding domain0Direct
SMAD/FHA domain0.000000000001653Direct
Flavoproteins0.000000000003454Direct
FAD-linked reductases, C-terminal domain0.0000000007438Direct
Ferritin-like0.00000001842Direct
PDZ domain-like0.0000003148Direct
Cytochrome P4500.006965Inherited
Riboflavin synthase domain-like0.06511Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.1166Inherited
Bet v1-like0.7834Inherited
ISP domain1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
51905,51905
  • 51905 - FAD/NAD(P)-binding domain
  • 51905 - FAD/NAD(P)-binding domain
    		• 0Direct
    56512,52218
  • 56512 - Nitric oxide (NO) synthase oxygenase domain
  • 52218 - Flavoproteins
    		• 0Direct
    54292,63380
  • 54292 - 2Fe-2S ferredoxin-like
  • 63380 - Riboflavin synthase domain-like
    		• 0.0000000000746Direct
    51905,54373
  • 51905 - FAD/NAD(P)-binding domain
  • 54373 - FAD-linked reductases, C-terminal domain
    		• 0.0000000003184Direct
    52218,63380
  • 52218 - Flavoproteins
  • 63380 - Riboflavin synthase domain-like
    		• 0.0018Inherited
    50022,55961
  • 50022 - ISP domain
  • 55961 - Bet v1-like
    		• 0.4992Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    56512,52218,63380
  • 56512 - Nitric oxide (NO) synthase oxygenase domain
  • 52218 - Flavoproteins
  • 63380 - Riboflavin synthase domain-like
    		• 0Direct
    54292,63380,52343
  • 54292 - 2Fe-2S ferredoxin-like
  • 63380 - Riboflavin synthase domain-like
  • 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain
    		• 0.0000000000746Direct

    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this EC term
    Plot tree as:   Download Newick format tree:
    (show help)
    Please cite: Gough, J., Karplus, K., Hughey, R. and Chothia, C. (2001). "Assignment of Homology to Genome Sequences using a Library of Hidden Markov Models that Represent all Proteins of Known Structure." J. Mol. Biol., 313(4), 903-919.

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    © Copyright 2017 The SUPERFAMILY authors and Julian Gough.