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  Home > GO hierarchy > With NAD(+) or NADP(+) as acceptor

With NAD(+) or NADP(+) as acceptor

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Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   root [root] <6>
+ + 2:   Oxidoreductases [1] <23>(183|263) (202|169|83)
+ 1:   Acting on the CH-CH group of donors [1.3] <8>(32|36) (34|23|12)
0:   With NAD(+) or NADP(+) as acceptor [1.3.1] <92>(23|22) (24|17|10)
- 1:   (+)-pulegone reductase [1.3.1.81](0|0) (0|0|0)
- 1:   (-)-isopiperitenone reductase [1.3.1.82](0|0) (0|0|0)
- 1:   (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicar [1.3.1.53](0|0) (0|0|0)
- 1:   1,2-dihydrovomilenine reductase [1.3.1.73](0|0) (0|0|0)
- 1:   1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxyla [1.3.1.68](0|0) (0|0|0)
- 1:   1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate deh [1.3.1.25](0|0) (0|0|0)
- 1:   12-oxophytodienoate reductase [1.3.1.42](1|1) (1|0|0)
- 1:   15-oxoprostaglandin 13-oxidase [1.3.1.48](1|2) (1|2|1)
- 1:   2'-hydroxydaidzein reductase [1.3.1.51](0|0) (0|0|0)
- 1:   2'-hydroxyisoflavone reductase [1.3.1.45](0|0) (0|0|0)
- 1:   2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase [1.3.1.28](0|0) (0|0|0)
- 1:   2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase [1.3.1.58](0|0) (0|0|0)
- 1:   2,4-dichlorobenzoyl-CoA reductase [1.3.1.63](0|0) (0|0|0)
- 1:   2,4-dienoyl-CoA reductase (NADPH) [1.3.1.34](0|1) (0|0|0)
- 1:   2-alkenal reductase [1.3.1.74](1|2) (1|2|1)
- 1:   2-coumarate reductase [1.3.1.11](0|0) (0|0|0)
- 1:   2-enoate reductase [1.3.1.31](0|0) (0|0|0)
- 1:   2-hexadecenal reductase [1.3.1.27](0|0) (0|0|0)
- 1:   2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductas [1.3.1.40](0|0) (0|0|0)
- 1:   2-methyl-branched-chain-enoyl-CoA reductase [1.3.1.52](0|0) (0|0|0)
- 1:   3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propan [1.3.1.87](0|1) (0|0|0)
- 1:   3-methyleneoxindole reductase [1.3.1.17](0|0) (0|0|0)
- 1:   5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroqui [1.3.1.65](0|0) (0|0|0)
- 1:   7-dehydrocholesterol reductase [1.3.1.21](0|0) (0|0|0)
- 1:   Acrylyl-CoA reductase (NADPH) [1.3.1.84](0|0) (0|0|0)
- 1:   Acyl-CoA dehydrogenase (NADP(+)) [1.3.1.8](0|0) (0|0|0)
- 1:   Alpha-santonin 1,2-reductase [1.3.1.47](0|0) (0|0|0)
- 1:   Anthocyanidin reductase [1.3.1.77](0|0) (0|0|0)
- 1:   Arogenate dehydrogenase [1.3.1.43](0|0) (0|0|0)
- 1:   Arogenate dehydrogenase (NAD(P)(+)) [1.3.1.79](0|0) (0|0|0)
- 1:   Arogenate dehydrogenase (NADP(+)) [1.3.1.78](0|0) (0|0|0)
- 1:   Beta-nitroacrylate reductase [1.3.1.16](0|0) (0|0|0)
- 1:   Biliverdin reductase [1.3.1.24](0|0) (0|0|0)
- 1:   Biochanin-A reductase [1.3.1.46](0|0) (0|0|0)
- 1:   Cholestenone 5-alpha-reductase [1.3.1.22](0|0) (0|0|0)
- 1:   Cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydroge [1.3.1.29](0|0) (0|0|0)
- 1:   Cis-1,2-dihydrobenzene-1,2-diol dehydrogenase [1.3.1.19](0|0) (0|0|0)
- 1:   Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase [1.3.1.56](0|1) (0|0|0)
- 1:   Cis-2-enoyl-CoA reductase (NADPH) [1.3.1.37](0|0) (0|0|0)
- 1:   Cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase [1.3.1.49](0|0) (0|0|0)
- 1:   Cis-dihydroethylcatechol dehydrogenase [1.3.1.66](0|0) (0|0|0)
- 1:   Cortisone alpha-reductase [1.3.1.4](0|0) (0|0|0)
- 1:   Crotonyl-CoA carboxylase/reductase [1.3.1.85](0|0) (0|0|0)
- 1:   Crotonyl-CoA reductase [1.3.1.86](0|0) (0|0|0)
- 1:   Cucurbitacin Delta(23)-reductase [1.3.1.5](0|0) (0|0|0)
- 1:   Deleted entry [1.3.1.23](0|0) (0|0|0)
- 1:   Deleted entry [1.3.1.61](0|0) (0|0|0)
- 1:   Deleted entry [1.3.1.59](0|0) (0|0|0)
- 1:   Deleted entry [1.3.1.55](0|0) (0|0|0)
- 1:   Delta(14)-sterol reductase [1.3.1.70](0|0) (0|0|0)
- 1:   Delta(24(24(1)))-sterol reductase [1.3.1.71](0|0) (0|0|0)
- 1:   Delta(24)-sterol reductase [1.3.1.72](1|0) (1|0|0)
- 1:   Delta(4)-3-oxosteroid 5-beta-reductase [1.3.1.3](0|0) (1|0|0)
- 1:   Dibenzothiophene dihydrodiol dehydrogenase [1.3.1.60](0|0) (0|0|0)
- 1:   Dihydrodipicolinate reductase [1.3.1.26](2|2) (2|1|0)
- 1:   Dihydroorotate dehydrogenase (NAD(+)) [1.3.1.14](1|1) (1|0|0)
- 1:   Dihydroorotate dehydrogenase (NADP(+)) [1.3.1.15](0|0) (0|0|0)
- 1:   Dihydropyrimidine dehydrogenase (NADP(+)) [1.3.1.2](4|4) (4|4|3)
- 1:   Dihydrouracil dehydrogenase (NAD(+)) [1.3.1.1](0|0) (3|2|0)
- 1:   Divinyl chlorophyllide a 8-vinyl-reductase [1.3.1.75](0|0) (0|0|0)
- 1:   Enoyl-[acyl-carrier-protein] reductase (NADH) [1.3.1.9](2|3) (2|1|0)
- 1:   Enoyl-[acyl-carrier-protein] reductase (NADPH, A-s [1.3.1.39](0|0) (0|0|0)
- 1:   Enoyl-[acyl-carrier-protein] reductase (NADPH, B-s [1.3.1.10](7|7) (7|5|3)
- 1:   Fumarate reductase (NADH) [1.3.1.6](0|0) (0|0|0)
- 1:   Geissoschizine dehydrogenase [1.3.1.36](0|0) (0|0|0)
- 1:   Geranylgeranyl diphosphate reductase [1.3.1.83](1|0) (1|0|0)
- 1:   Kynurenate-7,8-dihydrodiol dehydrogenase [1.3.1.18](0|0) (0|0|0)
- 1:   Maleylacetate reductase [1.3.1.32](1|1) (1|0|0)
- 1:   Meso-tartrate dehydrogenase [1.3.1.7](0|0) (0|0|0)
- 1:   Phloroglucinol reductase [1.3.1.57](0|0) (0|0|0)
- 1:   Phosphatidylcholine desaturase [1.3.1.35](0|0) (0|0|0)
- 1:   Phthalate 4,5-cis-dihydrodiol dehydrogenase [1.3.1.64](0|0) (0|0|0)
- 1:   Pimeloyl-CoA dehydrogenase [1.3.1.62](0|0) (0|0|0)
- 1:   Precorrin-2 dehydrogenase [1.3.1.76](2|3) (2|2|1)
- 1:   Precorrin-6A reductase [1.3.1.54](0|0) (0|0|0)
- 1:   Prephenate dehydrogenase [1.3.1.12](2|2) (3|3|2)
- 1:   Prephenate dehydrogenase (NADP(+)) [1.3.1.13](0|0) (0|0|0)
- 1:   Progesterone 5-alpha-reductase [1.3.1.30](0|0) (0|0|0)
- 1:   Protochlorophyllide reductase [1.3.1.33](0|1) (0|0|0)
- 1:   Red chlorophyll catabolite reductase [1.3.1.80](0|0) (0|0|0)
- 1:   Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase [1.3.1.20](0|1) (1|0|0)
- 1:   Trans-2-enoyl-CoA reductase (NAD(+)) [1.3.1.44](0|0) (0|0|0)
- 1:   Trans-2-enoyl-CoA reductase (NADPH) [1.3.1.38](2|2) (2|1|0)
- 1:   Transferred entry: 1.1.1.252 [1.3.1.50](0|0) (0|0|0)
- 1:   Transferred entry: 1.3.1.87 [1.3.1.n1](0|0) (0|0|0)
- 1:   Xanthommatin reductase [1.3.1.41](0|0) (0|0|0)
- 1:   Zeatin reductase [1.3.1.69](0|0) (0|0|0)
- 1:   dehydrogenase [1.3.1.67](0|0) (0|0|0)
- 1:   tRNA-dihydrouridine(16/17) synthase (NAD(P)(+)) [1.3.1.88](0|0) (0|0|0)
- 1:   tRNA-dihydrouridine(20) synthase (NAD(P)(+)) [1.3.1.91](0|0) (0|0|0)
- 1:   tRNA-dihydrouridine(20a/20b) synthase (NAD(P)(+)) [1.3.1.90](0|0) (0|0|0)
- 1:   tRNA-dihydrouridine(47) synthase (NAD(P)(+)) [1.3.1.89](1|1) (1|0|0)

Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP term FDR (all) Annotation (direct or inherited)
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain0Direct
Tetrapyrrole methylase0Direct
GroES-like0Direct
NAD(P)-binding Rossmann-fold domains0Direct
Siroheme synthase middle domains-like0Direct
Nucleotide-binding domain0Direct
FabD/lysophospholipase-like0.000000005964Direct
NAD(P)-linked oxidoreductase0.0000000233Direct
Probable ACP-binding domain of malonyl-CoA ACP transacylase0.0000005828Direct
ACP-like0.00003892Direct
ACT-like0.0001141Direct
Ubiquitin-like0.0001199Direct
4Fe-4S ferredoxins0.0002449Direct
6-phosphogluconate dehydrogenase C-terminal domain-like0.001254Inherited
Thioesterase/thiol ester dehydrase-isomerase0.001394Inherited
Dehydroquinate synthase-like0.03655Inherited
Thiolase-like0.4019Inherited
FAD-binding/transporter-associated domain-like0.4375Inherited
alpha/beta-Hydrolases0.8558Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
alpha-helical ferredoxin1Inherited
FAD/NAD(P)-binding domain1Inherited
FMN-linked oxidoreductases1Inherited

Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP term FDR (all) Annotation (direct or inherited)
Siroheme synthase middle domains-like0Direct
Tyrosine-dependent oxidoreductases0Direct
Dihydrodipicolinate reductase-like0Direct
Alcohol dehydrogenase-like, N-terminal domain0Direct
Siroheme synthase N-terminal domain-like0Direct
TyrA dimerization domain-like0Direct
Alcohol dehydrogenase-like, C-terminal domain0Direct
Tetrapyrrole methylase0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain0Direct
Dihydropyrimidine dehydrogenase, N-terminal domain0Direct
N-terminal domain of adrenodoxin reductase-like0Direct
Acyl-carrier protein (ACP)0.00000000000007829Direct
FabD-like0.0000000000001159Direct
Glucose 6-phosphate dehydrogenase-like0.0000000000009211Direct
Thioesterase domain of polypeptide, polyketide and fatty acid synthases0.0000000001222Direct
MaoC-like0.0000000008482Direct
Aldo-keto reductases (NADP)0.0000000261Direct
Iron-containing alcohol dehydrogenase0.0000003122Direct
Ferredoxin domains from multidomain proteins0.000001422Direct
Thiolase-related0.01279Inherited
6-phosphogluconate dehydrogenase-like, N-terminal domain0.01378Inherited
FMN-linked oxidoreductases1Inherited

Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this EC term
Plot tree as:   Download Newick format tree:
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Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
NAD(P)-binding Rossmann-fold domains0Direct
GroES-like0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain0Direct
Siroheme synthase middle domains-like0Direct
Tetrapyrrole methylase0Direct
Nucleotide-binding domain0Direct
FabD/lysophospholipase-like0.000000004601Direct
NAD(P)-linked oxidoreductase0.00000001819Direct
Chorismate mutase II0.000000354Direct
Probable ACP-binding domain of malonyl-CoA ACP transacylase0.0000004653Direct
ACP-like0.00003183Direct
ACT-like0.00009346Direct
Ubiquitin-like0.00009904Direct
4Fe-4S ferredoxins0.0002069Direct
6-phosphogluconate dehydrogenase C-terminal domain-like0.001171Inherited
Thioesterase/thiol ester dehydrase-isomerase0.001305Inherited
Dehydroquinate synthase-like0.03191Inherited
Thiolase-like0.3697Inherited
FAD-binding/transporter-associated domain-like0.4065Inherited
alpha/beta-Hydrolases0.8067Inherited
FAD/NAD(P)-binding domain1Inherited
FMN-linked oxidoreductases1Inherited
alpha-helical ferredoxin1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
46548,51971
  • 46548 - alpha-helical ferredoxin
  • 51971 - Nucleotide-binding domain
    		• 0Direct
    48179,55021
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 55021 - ACT-like
    		• 0Direct
    48600,51735
  • 48600 - Chorismate mutase II
  • 51735 - NAD(P)-binding Rossmann-fold domains
    		• 0Direct
    51395,54862
  • 51395 - FMN-linked oxidoreductases
  • 54862 - 4Fe-4S ferredoxins
    		• 0Direct
    51971,51395
  • 51971 - Nucleotide-binding domain
  • 51395 - FMN-linked oxidoreductases
    		• 0Direct
    51735,55347
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
    		• 0Direct
    54637,52151
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 52151 - FabD/lysophospholipase-like
    		• 0Direct
    75615,53790
  • 75615 - Siroheme synthase middle domains-like
  • 53790 - Tetrapyrrole methylase
    		• 0Direct
    50129,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
    		• 0Direct
    51735,75615
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 75615 - Siroheme synthase middle domains-like
    		• 0Direct
    51971,51971
  • 51971 - Nucleotide-binding domain
  • 51971 - Nucleotide-binding domain
    		• 3.502e-16Direct
    47336,53474
  • 47336 - ACP-like
  • 53474 - alpha/beta-Hydrolases
    		• 0.0000000000004171Direct
    51735,50129
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 50129 - GroES-like
    		• 0.00000000001654Direct
    51735,51735
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
    		• 0.0000000002668Direct
    51735,47336
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
    		• 0.000000003834Direct
    52151,55048
  • 52151 - FabD/lysophospholipase-like
  • 55048 - Probable ACP-binding domain of malonyl-CoA ACP transacylase
    		• 0.0000004653Direct
    51735,48179
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
    		• 0.001162Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    51971,51971,51395
  • 51971 - Nucleotide-binding domain
  • 51971 - Nucleotide-binding domain
  • 51395 - FMN-linked oxidoreductases
    		• 0Direct
    51735,48179,55021
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 55021 - ACT-like
    		• 0Direct
    46548,51971,51971
  • 46548 - alpha-helical ferredoxin
  • 51971 - Nucleotide-binding domain
  • 51971 - Nucleotide-binding domain
    		• 0Direct
    48600,51735,48179
  • 48600 - Chorismate mutase II
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
    		• 0Direct
    51735,75615,53790
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 75615 - Siroheme synthase middle domains-like
  • 53790 - Tetrapyrrole methylase
    		• 0Direct
    51971,51395,54862
  • 51971 - Nucleotide-binding domain
  • 51395 - FMN-linked oxidoreductases
  • 54862 - 4Fe-4S ferredoxins
    		• 0Direct
    51735,47336,53474
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 53474 - alpha/beta-Hydrolases
    		• 0.00000000000006057Direct
    50129,51735,50129
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 50129 - GroES-like
    		• 0.000000000009095Direct
    50129,51735,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
    		• 0.00000000005187Direct
    51735,51735,47336
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
    		• 0.000000002023Direct

    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this EC term
    Plot tree as:   Download Newick format tree:
    (show help)
    Please cite: Gough, J., Karplus, K., Hughey, R. and Chothia, C. (2001). "Assignment of Homology to Genome Sequences using a Library of Hidden Markov Models that Represent all Proteins of Known Structure." J. Mol. Biol., 313(4), 903-919.

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    © Copyright 2013 The SUPERFAMILY authors and Julian Gough.