CTD Diseases (CD): Neoplasms 

Root: CD Hierarchy (CTD diseases from Comparative Toxicogenomics Database)

Shortest distance to current term (+ for parents, - for children)	CD term [CD ID] <#Children>	#Domains (Superfamily|Family)	#Supra-domain (Single|Duplex|Triple)
+ 1:	Diseases [MESH:C] <25>
0:	Neoplasms [MESH:D009369] <18>	(68|96)	(74|65|31)
- 1:	Cysts [MESH:D003560] <36>	(1|1)	(1|0|0)
- 1:	Neoplastic Syndromes, Hereditary [MESH:D009386] <29>	(4|3)	(4|2|0)
- 1:	Neoplasms by Site [MESH:D009371] <17>	(38|55)	(44|41|19)
- 1:	Neoplasms by Histologic Type [MESH:D009370] <14>	(45|58)	(49|32|21)
- 1:	Hamartoma [MESH:D006222] <12>	(0|0)	(0|0|0)
- 1:	Neoplasms, Experimental [MESH:D009374] <10>	(3|2)	(3|1|0)
- 1:	Precancerous Conditions [MESH:D011230] <10>	(0|0)	(0|0|0)
- 1:	Neoplastic Processes [MESH:D009385] <8>	(6|8)	(8|4|2)
- 1:	Neoplasms, Multiple Primary [MESH:D009378] <4>	(0|0)	(0|0|0)
- 1:	Paraneoplastic Syndromes [MESH:D010257] <4>	(0|0)	(0|0|0)
- 1:	Neoplasms, Radiation-Induced [MESH:D009381] <3>	(0|0)	(0|0|0)
- 1:	Pregnancy Complications, Neoplastic [MESH:D011252] <1>	(0|0)	(0|0|0)
- 1:	Chromosomal Instability with Tissue-Specific Radiosensitivity [MESH:C565848]	(0|0)	(0|0|0)
- 1:	Neoplasms, Hormone-Dependent [MESH:D009376]	(1|1)	(1|0|0)
- 1:	Neoplasms, Post-Traumatic [MESH:D017169]	(0|0)	(0|0|0)
- 1:	Neoplasms, Second Primary [MESH:D016609]	(0|0)	(0|0|0)
- 1:	TUMOR PREDISPOSITION SYNDROME [OMIM:614327]	(0|0)	(0|0|0)
- 1:	abc disease [MESH:C579754]	(0|0)	(0|0|0)

Superfamily

Highlighted in gray are those with FDR_all>0.001

SCOP term	FDR (all)	Annotation (direct or inherited)
p53 tetramerization domain	0	DIRECT
Inhibitor of apoptosis (IAP) repeat	0	DIRECT
SPOC domain-like	0	DIRECT
SWIB/MDM2 domain	0	DIRECT
HSP90 C-terminal domain	0	DIRECT
Translational machinery components	0	DIRECT
Aconitase iron-sulfur domain	0	DIRECT
Bcl-2 inhibitors of programmed cell death	0	DIRECT
Glutamine synthetase/guanido kinase	0	DIRECT
Orange domain-like	0	DIRECT
DNA repair protein MutS, domain III	0	DIRECT
Nuclear receptor coactivator interlocking domain	0	DIRECT
LeuD/IlvD-like	0	DIRECT
RGC domain-like	0	DIRECT
Protein kinase-like (PK-like)	0.0003906	DIRECT
HLH, helix-loop-helix DNA-binding domain	0.00171	INHERITED FROM: Burkitt Lymphoma || Neoplasms, Neuroepithelial || Neuroectodermal Tumors
ABC transporter transmembrane region	0.002302	INHERITED FROM: Gastrointestinal Neoplasms || Digestive System Neoplasms || Neoplasms by Site || Intestinal Neoplasms || Colorectal Neoplasms || Squamous Cell Carcinoma of Head and Neck
HMG-box	0.003777	INHERITED FROM: Lymphoma, T-Cell, Cutaneous
Growth factor receptor domain	0.005306	INHERITED FROM: Skin Neoplasms || Glioma || Biliary Tract Neoplasms || Carcinoma, Ductal || Gallbladder Neoplasms
Annexin	0.007467	INHERITED FROM: Leukemia, Myeloid || Mouth Neoplasms || Leukemia, Myeloid, Acute
Cyclin-like	0.00884	INHERITED FROM: Carcinoma, Squamous Cell || Head and Neck Neoplasms || Neoplasms, Squamous Cell || Squamous Cell Carcinoma of Head and Neck
Prefoldin	0.01052	INHERITED FROM: Carcinoma
PGBD-like	0.01052	INHERITED FROM: Astrocytoma || Neoplastic Processes
SET domain	0.01775	INHERITED FROM: Cell Transformation, Neoplastic || Leukemia
PYP-like sensor domain (PAS domain)	0.02061	INHERITED FROM: Leukemia, Myelogenous, Chronic, BCR-ABL Positive || Breast Neoplasms
Cytochrome P450	0.02135	INHERITED FROM: Prostatic Neoplasms || Neoplasms by Site
STAT	0.02357	INHERITED FROM: Leukemia, Lymphoid || Precursor Cell Lymphoblastic Leukemia-Lymphoma
Metallothionein	0.02357	INHERITED FROM: Urinary Bladder Neoplasms || Carcinoma, Hepatocellular
Transcription factor STAT-4 N-domain	0.02357	INHERITED FROM: Leukemia, Lymphoid || Precursor Cell Lymphoblastic Leukemia-Lymphoma
Multidrug efflux transporter AcrB transmembrane domain	0.02357	INHERITED FROM: Neoplasms, Connective and Soft Tissue || Digestive System Neoplasms || Gastrointestinal Stromal Tumors || Neoplasms, Connective Tissue
Nuclear receptor ligand-binding domain	0.03031	INHERITED FROM: Prostatic Intraepithelial Neoplasia
Bromodomain	0.04001	INHERITED FROM: Medulloblastoma || Lymphoma, T-Cell || Small Cell Lung Carcinoma || Carcinoma, Transitional Cell || Urogenital Neoplasms
Ribosomal protein S5 domain 2-like	0.04329	INHERITED FROM: Colorectal Neoplasms, Hereditary Nonpolyposis || Neoplastic Syndromes, Hereditary
4-helical cytokines	0.04578	INHERITED FROM: Endocrine Gland Neoplasms || Sarcoma || Leukemia-Lymphoma, Adult T-Cell || Neoplasms, Experimental || Neoplasms, Plasma Cell || Carcinoma, Transitional Cell || Nevi and Melanomas
Tudor/PWWP/MBT	0.04874	INHERITED FROM: Glioma
p53-like transcription factors	0.05681	INHERITED FROM: Cell Transformation, Neoplastic || Lymphoma, T-Cell
Kringle-like	0.06143	INHERITED FROM: Astrocytoma || Neoplasms, Experimental || Bone Neoplasms || Neoplastic Processes
Glucocorticoid receptor-like (DNA-binding domain)	0.06394	INHERITED FROM: Prostatic Intraepithelial Neoplasia
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	0.06542	INHERITED FROM: Colorectal Neoplasms, Hereditary Nonpolyposis || Neoplastic Syndromes, Hereditary
Notch domain	0.07075	INHERITED FROM: Carcinoma, Squamous Cell || Skin Neoplasms || Endocrine Gland Neoplasms || Glioma || Astrocytoma || Glioblastoma || Neoplasms, Squamous Cell || Carcinoma, Ductal || Breast Neoplasms || Neoplasms, Ductal, Lobular, and Medullary || Esophageal Neoplasms || Pancreatic Neoplasms
Serum albumin-like	0.07075	INHERITED FROM: Stomach Neoplasms
E2F-DP heterodimerization region	0.07151	INHERITED FROM: Thoracic Neoplasms || Respiratory Tract Neoplasms || Lung Neoplasms || Carcinoma, Non-Small-Cell Lung
Hemopexin-like domain	0.0757	INHERITED FROM: Neoplastic Processes
vWA-like	0.09872	INHERITED FROM: Leukemia, Promyelocytic, Acute
DEATH domain	0.1029	INHERITED FROM: Lymphoma, Non-Hodgkin || Carcinoma, Renal Cell
Lamin A/C globular tail domain	0.1227	INHERITED FROM: Thoracic Neoplasms || Respiratory Tract Neoplasms || Lung Neoplasms
Cytokine	0.1399	INHERITED FROM: Mesothelioma
dsRNA-binding domain-like	0.1454	INHERITED FROM: Neoplasms, Complex and Mixed || Neoplastic Syndromes, Hereditary || Wilms Tumor
Interleukin 8-like chemokines	0.2026	INHERITED FROM: Thoracic Neoplasms || Adenoma || Mesothelioma, Malignant || Neoplasms, Mesothelial || Mesothelioma
beta-beta-alpha zinc fingers	0.2044	INHERITED FROM: Adenocarcinoma, Papillary
Integrin domains	0.2166	INHERITED FROM: Leukemia, Promyelocytic, Acute || Leukemia, Myeloid, Acute
Ran binding protein zinc finger-like	0.2507	INHERITED FROM: Sarcoma
SH2 domain	0.2519	INHERITED FROM: Leukemia
C2 domain (Calcium/lipid-binding domain, CaLB)	0.329	INHERITED FROM: Lymphoma, Non-Hodgkin || Lymphoma, Large B-Cell, Diffuse || Lymphoma
Frizzled cysteine-rich domain	0.3433	INHERITED FROM: Colorectal Neoplasms
WW domain	0.4246	INHERITED FROM: Neoplasms, Muscle Tissue || Sarcoma || Myosarcoma
SMAD MH1 domain	0.4315	INHERITED FROM: Intestinal Neoplasms || Colorectal Neoplasms
Integrin alpha N-terminal domain	0.4364	INHERITED FROM: Leukemia, Promyelocytic, Acute
L domain-like	0.4943	INHERITED FROM: Biliary Tract Neoplasms || Gallbladder Neoplasms
MHC antigen-recognition domain	0.5006	INHERITED FROM: Pharyngeal Neoplasms || Oropharyngeal Neoplasms || Otorhinolaryngologic Neoplasms
Plexin repeat	0.5006	INHERITED FROM: Endometrial Neoplasms
Immunoglobulin	0.5368	INHERITED FROM: Oropharyngeal Neoplasms
NAD(P)-linked oxidoreductase	0.5423	INHERITED FROM: Cell Transformation, Neoplastic || Neoplasms, Hormone-Dependent || Genital Neoplasms, Female || Endometrial Neoplasms || Polycystic Ovary Syndrome || Uterine Neoplasms
Ankyrin repeat	0.562	INHERITED FROM: Neoplasms, Ductal, Lobular, and Medullary
Clc chloride channel	0.6826	INHERITED FROM: Glioma
ARM repeat	0.6954	INHERITED FROM: Adenocarcinoma Of Esophagus
Sema domain	0.7798	INHERITED FROM: Endometrial Neoplasms
FAD/NAD(P)-binding domain	0.9908	INHERITED FROM: Paraganglioma

Family

Highlighted in gray are those with FDR_all>0.001

SCOP term	FDR (all)	Annotation (direct or inherited)
DNA gyrase/MutL, second domain	0	DIRECT
PDI-like	0	DIRECT
Phoshoinositide 3-kinase (PI3K) helical domain	0	DIRECT
DNA repair protein MutS, domain III	0	DIRECT
Bcl-2 inhibitors of programmed cell death	0	DIRECT
HSP90 C-terminal domain	0	DIRECT
Ubiquitin carboxyl-terminal hydrolase UCH-L	0	DIRECT
Kinase associated domain 1, KA1	0	DIRECT
Ribosomal protein L18 and S11	0	DIRECT
C5 cytosine-specific DNA methylase, DCM	0	DIRECT
Inhibitor of apoptosis (IAP) repeat	0	DIRECT
Multidrug efflux transporter AcrB transmembrane domain	0	DIRECT
DNA gyrase/MutL, N-terminal domain	0	DIRECT
CUT domain	0	DIRECT
Linker histone H1/H5	0	DIRECT
Phoshoinositide 3-kinase (PI3K), catalytic domain	0	DIRECT
Tissue inhibitor of metalloproteinases, TIMP	0	DIRECT
Formate/glycerate dehydrogenases, substrate-binding domain	0	DIRECT
Transferrin	0	DIRECT
Aconitase iron-sulfur domain	0	DIRECT
Nuclear receptor coactivator interlocking domain	0	DIRECT
p53 tetramerization domain	0	DIRECT
Hairy Orange domain	0	DIRECT
Histone lysine methyltransferases	0	DIRECT
2Fe-2S ferredoxin domains from multidomain proteins	0	DIRECT
SWIB/MDM2 domain	0	DIRECT
Heat shock protein 90, HSP90, N-terminal domain	0	DIRECT
PAS domain of steroid receptor coactivator 1A, NCo-A1	0	DIRECT
LeuD-like	0	DIRECT
RGC domain	0	DIRECT
DEATH effector domain, DED	0	DIRECT
Hsp90 middle domain	0	DIRECT
p53 DNA-binding domain-like	0	DIRECT
ABC transporter ATPase domain-like	0.000009372	DIRECT
Growth factor receptor domain	0.0006281	DIRECT
Protein kinases, catalytic subunit	0.001002	INHERITED FROM: Biliary Tract Neoplasms
HLH, helix-loop-helix DNA-binding domain	0.002336	INHERITED FROM: Burkitt Lymphoma || Neoplasms, Neuroepithelial || Neuroectodermal Tumors
PHD domain	0.003631	INHERITED FROM: Lymphoma, T-Cell, Cutaneous
ABC transporter transmembrane region	0.003986	INHERITED FROM: Gastrointestinal Neoplasms || Digestive System Neoplasms || Neoplasms by Site || Intestinal Neoplasms || Colorectal Neoplasms || Squamous Cell Carcinoma of Head and Neck
HMG-box	0.004215	INHERITED FROM: Lymphoma, T-Cell, Cutaneous
Cyclin	0.006315	INHERITED FROM: Head and Neck Neoplasms || Neoplasms, Squamous Cell || Genital Neoplasms, Female || Squamous Cell Carcinoma of Head and Neck || Carcinoma
Annexin	0.006866	INHERITED FROM: Leukemia, Myeloid || Mouth Neoplasms || Leukemia, Myeloid, Acute
ets domain	0.009987	INHERITED FROM: Prostatic Neoplasms || Precursor Cell Lymphoblastic Leukemia-Lymphoma
MMP N-terminal domain	0.01028	INHERITED FROM: Astrocytoma || Neoplastic Processes
Fibronectin type II module	0.01222	INHERITED FROM: Liver Neoplasms || Glioma || Astrocytoma || Glioblastoma || Neoplasms, Experimental || Neoplasm Invasiveness || Mammary Neoplasms, Animal || Carcinoma
Cystatins	0.01222	INHERITED FROM: Neoplasms, Nerve Tissue
Platelet-derived growth factor-like	0.01222	INHERITED FROM: Neoplasms, Connective and Soft Tissue || Neoplasms, Vascular Tissue
Matrix metalloproteases, catalytic domain	0.0154	INHERITED FROM: Astrocytoma || Neoplastic Processes
STAT	0.02161	INHERITED FROM: Leukemia, Lymphoid || Precursor Cell Lymphoblastic Leukemia-Lymphoma
Metallothionein	0.02161	INHERITED FROM: Urinary Bladder Neoplasms || Carcinoma, Hepatocellular
L domain	0.02161	INHERITED FROM: Nasopharyngeal Neoplasms || Pharyngeal Neoplasms || Biliary Tract Neoplasms || Gallbladder Neoplasms || Otorhinolaryngologic Neoplasms
STAT DNA-binding domain	0.02161	INHERITED FROM: Leukemia, Lymphoid || Precursor Cell Lymphoblastic Leukemia-Lymphoma
Transcription factor STAT-4 N-domain	0.02161	INHERITED FROM: Leukemia, Lymphoid || Precursor Cell Lymphoblastic Leukemia-Lymphoma
Cell cycle transcription factor e2f-dp	0.02604	INHERITED FROM: Thoracic Neoplasms || Respiratory Tract Neoplasms || Carcinoma, Bronchogenic || Lung Neoplasms || Carcinoma, Non-Small-Cell Lung || Bronchial Neoplasms
Nuclear receptor	0.03202	INHERITED FROM: Prostatic Intraepithelial Neoplasia || Carcinoma in Situ
Cytochrome P450	0.03202	INHERITED FROM: Prostatic Neoplasms
Nuclear receptor ligand-binding domain	0.0344	INHERITED FROM: Prostatic Intraepithelial Neoplasia || Carcinoma in Situ
Prefoldin	0.03694	INHERITED FROM: Esophageal Squamous Cell Carcinoma || Esophageal Neoplasms
E2F dimerization segment	0.03694	INHERITED FROM: Thoracic Neoplasms || Respiratory Tract Neoplasms || Carcinoma, Bronchogenic || Lung Neoplasms || Carcinoma, Non-Small-Cell Lung || Bronchial Neoplasms
S100 proteins	0.03939	INHERITED FROM: Medulloblastoma || Neuroectodermal Tumors, Primitive
p120GAP domain-like	0.04153	INHERITED FROM: Nervous System Neoplasms
Bromodomain	0.04211	INHERITED FROM: Medulloblastoma || Lymphoma, T-Cell || Small Cell Lung Carcinoma || Carcinoma, Transitional Cell || Urogenital Neoplasms
Interferons/interleukin-10 (IL-10)	0.06086	INHERITED FROM: Neuroendocrine Tumors || Leukemia, Lymphoid || Endocrine Gland Neoplasms || Leukemia-Lymphoma, Adult T-Cell || Neuroectodermal Tumors || Neoplasms, Germ Cell and Embryonal || Neoplasms, Nerve Tissue || Intestinal Neoplasms || Nevi and Melanomas || Pancreatic Neoplasms
DEATH domain, DD	0.06247	INHERITED FROM: Lymphoma, Non-Hodgkin || Carcinoma, Renal Cell || Lymphoma, Large B-Cell, Diffuse
EGF-type module	0.06321	INHERITED FROM: Glioma || Carcinoma, Pancreatic Ductal || Carcinoma, Ductal || Neoplasms, Ductal, Lobular, and Medullary
Serum albumin-like	0.06464	INHERITED FROM: Stomach Neoplasms
Notch domain	0.06464	INHERITED FROM: Carcinoma, Squamous Cell || Skin Neoplasms || Endocrine Gland Neoplasms || Glioma || Astrocytoma || Glioblastoma || Neoplasms, Squamous Cell || Carcinoma, Ductal || Breast Neoplasms || Neoplasms, Ductal, Lobular, and Medullary || Esophageal Neoplasms || Pancreatic Neoplasms
Hemopexin-like domain	0.07598	INHERITED FROM: Astrocytoma || Neoplastic Processes
PWWP domain	0.09252	INHERITED FROM: Leukemia, Myeloid, Acute
Lamin A/C globular tail domain	0.1124	INHERITED FROM: Thoracic Neoplasms || Respiratory Tract Neoplasms || Lung Neoplasms
MBT repeat	0.1124	INHERITED FROM: Medulloblastoma || Glioma || Neoplasms, Neuroepithelial || Neuroectodermal Tumors || Neoplasms, Germ Cell and Embryonal || Neoplasms, Nerve Tissue || Neuroectodermal Tumors, Primitive
PLC-like (P variant)	0.1124	INHERITED FROM: Lymphoma, T-Cell, Cutaneous || Lymphoma, Non-Hodgkin || Lymphoma, Large B-Cell, Diffuse || Lymphoma
Short-chain cytokines	0.1132	INHERITED FROM: Mesothelioma
RecA protein-like (ATPase-domain)	0.1132	INHERITED FROM: Breast Neoplasms
Integrin A (or I) domain	0.1255	INHERITED FROM: Leukemia, Promyelocytic, Acute
Ras-binding domain, RBD	0.1458	INHERITED FROM: Lymphoma, Non-Hodgkin || Lymphoma, Large B-Cell, Diffuse || Lymphoma
Kringle modules	0.197	INHERITED FROM: Neoplasm Metastasis
Interleukin 8-like chemokines	0.217	INHERITED FROM: Thoracic Neoplasms || Adenoma || Mesothelioma, Malignant || Neoplasms, Mesothelial || Mesothelioma
Integrin domains	0.2215	INHERITED FROM: Leukemia, Promyelocytic, Acute || Leukemia, Myeloid, Acute
Classic zinc finger, C2H2	0.2293	INHERITED FROM: Adenocarcinoma, Papillary || Thyroid Cancer, Papillary
Ran binding protein zinc finger-like	0.2491	INHERITED FROM: Sarcoma
SH2 domain	0.289	INHERITED FROM: Leukemia
Integrin alpha N-terminal domain	0.3447	INHERITED FROM: Leukemia, Promyelocytic, Acute
Frizzled cysteine-rich domain	0.3447	INHERITED FROM: Colorectal Neoplasms
Fibroblast growth factors (FGF)	0.3635	INHERITED FROM: Mesothelioma
SMAD MH1 domain	0.4282	INHERITED FROM: Intestinal Neoplasms || Colorectal Neoplasms
SMAD domain	0.4282	INHERITED FROM: Intestinal Neoplasms || Colorectal Neoplasms
WW domain	0.4408	INHERITED FROM: Neoplasms, Muscle Tissue || Sarcoma || Myosarcoma
C1 set domains (antibody constant domain-like)	0.4422	INHERITED FROM: Pharyngeal Neoplasms || Oropharyngeal Neoplasms || Otorhinolaryngologic Neoplasms
Plexin repeat	0.518	INHERITED FROM: Endometrial Neoplasms
MHC antigen-recognition domain	0.518	INHERITED FROM: Pharyngeal Neoplasms || Oropharyngeal Neoplasms || Otorhinolaryngologic Neoplasms
Aldo-keto reductases (NADP)	0.5462	INHERITED FROM: Cell Transformation, Neoplastic || Neoplasms, Hormone-Dependent || Cysts || Genital Neoplasms, Female || Endometrial Neoplasms || Polycystic Ovary Syndrome || Uterine Neoplasms || Ovarian Cysts
Ankyrin repeat	0.5932	INHERITED FROM: Neoplasms, Ductal, Lobular, and Medullary
Clc chloride channel	0.6803	INHERITED FROM: Glioma || Neoplasms, Neuroepithelial
Sema domain	0.7878	INHERITED FROM: Genital Neoplasms, Female || Endometrial Neoplasms
G proteins	0.8839	INHERITED FROM: Nevus, Sebaceous of Jadassohn || Adenocarcinoma, Follicular || Leukemia, Myelomonocytic, Juvenile

Supra-domain (Single|Duplex|Triple)

Supra-domain (Single)

Highlighted in gray are those with FDR>0.001

Supra-domain (Single)	FDR (all)	Annotation (direct or inherited)
p53 tetramerization domain	0	DIRECT
Aconitase iron-sulfur domain	0	DIRECT
LeuD/IlvD-like	0	DIRECT
SPOC domain-like	0	DIRECT
Bcl-2 inhibitors of programmed cell death	0	DIRECT
Inhibitor of apoptosis (IAP) repeat	0	DIRECT
Translational machinery components	0	DIRECT
SWIB/MDM2 domain	0	DIRECT
Nuclear receptor coactivator interlocking domain	0	DIRECT
Glutamine synthetase/guanido kinase	0	DIRECT
Orange domain-like	0	DIRECT
HSP90 C-terminal domain	0	DIRECT
RGC domain-like	0	DIRECT
DNA repair protein MutS, domain III	0	DIRECT
Protein kinase-like (PK-like)	0.0002374	DIRECT
HLH, helix-loop-helix DNA-binding domain	0.001142	INHERITED FROM: Neoplasms, Ductal, Lobular, and Medullary || Neoplasms, Neuroepithelial || Carcinoma, Ductal || Burkitt Lymphoma || Neuroectodermal Tumors
ABC transporter transmembrane region	0.001562	INHERITED FROM: Digestive System Neoplasms || Colorectal Neoplasms || Neoplasms by Site || Gastrointestinal Neoplasms || Squamous Cell Carcinoma of Head and Neck || Intestinal Neoplasms
HMG-box	0.002634	INHERITED FROM: Lymphoma, T-Cell, Cutaneous
Growth factor receptor domain	0.003774	INHERITED FROM: Neoplasms, Ductal, Lobular, and Medullary || Carcinoma, Ductal || Neuroectodermal Tumors || Skin Neoplasms || Biliary Tract Neoplasms || Glioma || Gallbladder Neoplasms
Annexin	0.005441	INHERITED FROM: Leukemia, Myeloid, Acute || Mouth Neoplasms || Leukemia, Myeloid
Cyclin-like	0.006437	INHERITED FROM: Head and Neck Neoplasms || Neoplasms, Squamous Cell || Squamous Cell Carcinoma of Head and Neck || Carcinoma, Squamous Cell
PGBD-like	0.007624	INHERITED FROM: Colorectal Neoplasms || Astrocytoma || Neoplastic Processes
Prefoldin	0.007624	INHERITED FROM: Neoplasms by Site || Carcinoma || Cell Transformation, Neoplastic || Neoplasms, Glandular and Epithelial
SET domain	0.01333	INHERITED FROM: Carcinogenesis || Leukemia || Cell Transformation, Neoplastic
FYVE/PHD zinc finger	0.01355	INHERITED FROM: Carcinoma, Adenoid Cystic
PYP-like sensor domain (PAS domain)	0.01561	INHERITED FROM: Leukemia, Myelogenous, Chronic, BCR-ABL Positive || Breast Neoplasms
Cytochrome P450	0.01619	INHERITED FROM: Neoplasms by Site || Prostatic Neoplasms
Multidrug efflux transporter AcrB transmembrane domain	0.01801	INHERITED FROM: Digestive System Neoplasms || Neoplasms, Connective and Soft Tissue || Gastrointestinal Stromal Tumors || Neoplasms, Connective Tissue
Transcription factor STAT-4 N-domain	0.01801	INHERITED FROM: Precursor Cell Lymphoblastic Leukemia-Lymphoma || Leukemia, Lymphoid
STAT	0.01801	INHERITED FROM: Precursor Cell Lymphoblastic Leukemia-Lymphoma || Leukemia, Lymphoid
Metallothionein	0.01801	INHERITED FROM: Carcinoma, Hepatocellular || Urologic Neoplasms || Urinary Bladder Neoplasms
Nuclear receptor ligand-binding domain	0.02361	INHERITED FROM: Prostatic Intraepithelial Neoplasia || Carcinoma in Situ
Bromodomain	0.03152	INHERITED FROM: Medulloblastoma || Urogenital Neoplasms || Lymphoma, T-Cell || Carcinoma, Transitional Cell || Small Cell Lung Carcinoma
Ribosomal protein S5 domain 2-like	0.03434	INHERITED FROM: Colorectal Neoplasms, Hereditary Nonpolyposis || Neoplastic Syndromes, Hereditary
4-helical cytokines	0.03632	INHERITED FROM: Neoplasms, Plasma Cell || Sarcoma || Carcinoma, Transitional Cell || Endocrine Gland Neoplasms || Neoplasms, Experimental || Nevi and Melanomas || Leukemia-Lymphoma, Adult T-Cell
Tudor/PWWP/MBT	0.03883	INHERITED FROM: Medulloblastoma || Glioma
p53-like transcription factors	0.04558	INHERITED FROM: Lymphoma, T-Cell || Pancreatic Neoplasms || Cell Transformation, Neoplastic
Kringle-like	0.04974	INHERITED FROM: Astrocytoma || Neoplastic Processes || Neoplasms, Experimental || Bone Neoplasms
ARID-like	0.05148	INHERITED FROM: Adenocarcinoma
Glucocorticoid receptor-like (DNA-binding domain)	0.05194	INHERITED FROM: Prostatic Intraepithelial Neoplasia
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	0.05298	INHERITED FROM: Colorectal Neoplasms, Hereditary Nonpolyposis || Neoplastic Syndromes, Hereditary
"Winged helix" DNA-binding domain	0.05605	INHERITED FROM: Carcinoma, Non-Small-Cell Lung
Serum albumin-like	0.05757	INHERITED FROM: Stomach Neoplasms
Notch domain	0.05757	INHERITED FROM: Neoplasms, Ductal, Lobular, and Medullary || Astrocytoma || Carcinoma, Ductal || Pancreatic Neoplasms || Breast Neoplasms || Esophageal Neoplasms || Neoplasms, Squamous Cell || Endocrine Gland Neoplasms || Carcinoma, Squamous Cell || Glioblastoma || Neuroectodermal Tumors || Skin Neoplasms || Glioma
E2F-DP heterodimerization region	0.05816	INHERITED FROM: Carcinoma, Non-Small-Cell Lung || Lung Neoplasms || Respiratory Tract Neoplasms || Thoracic Neoplasms
Hemopexin-like domain	0.06187	INHERITED FROM: Astrocytoma || Neoplastic Processes
vWA-like	0.08215	INHERITED FROM: Leukemia, Promyelocytic, Acute
DEATH domain	0.08605	INHERITED FROM: Lymphoma, Non-Hodgkin || Carcinoma, Renal Cell
Lamin A/C globular tail domain	0.1036	INHERITED FROM: Lung Neoplasms || Respiratory Tract Neoplasms || Thoracic Neoplasms
Cytokine	0.1188	INHERITED FROM: Mesothelioma
dsRNA-binding domain-like	0.124	INHERITED FROM: Wilms Tumor || Neoplasms, Complex and Mixed || Neoplastic Syndromes, Hereditary
Interleukin 8-like chemokines	0.1768	INHERITED FROM: Mesothelioma || Mesothelioma, Malignant || Adenoma || Thoracic Neoplasms || Neoplasms, Mesothelial
beta-beta-alpha zinc fingers	0.1786	INHERITED FROM: Adenocarcinoma, Papillary
Integrin domains	0.1902	INHERITED FROM: Leukemia, Promyelocytic, Acute || Leukemia, Myeloid, Acute
Ran binding protein zinc finger-like	0.2225	INHERITED FROM: Sarcoma
Caspase-like	0.2225	INHERITED FROM: Lymphoma, Non-Hodgkin
SH2 domain	0.2235	INHERITED FROM: Leukemia || Leukemia, Myelomonocytic, Juvenile
C2 domain (Calcium/lipid-binding domain, CaLB)	0.2965	INHERITED FROM: Lymphoma, Non-Hodgkin || Lymphoma || Lymphoma, Large B-Cell, Diffuse
Frizzled cysteine-rich domain	0.3105	INHERITED FROM: Colorectal Neoplasms
WW domain	0.3899	INHERITED FROM: Neoplasms, Muscle Tissue || Myosarcoma || Sarcoma
SMAD MH1 domain	0.3971	INHERITED FROM: Colorectal Neoplasms || Intestinal Neoplasms
Lipase/lipooxygenase domain (PLAT/LH2 domain)	0.4019	INHERITED FROM: Colonic Neoplasms
Integrin alpha N-terminal domain	0.4019	INHERITED FROM: Leukemia, Promyelocytic, Acute
Intermediate filament protein, coiled coil region	0.413	INHERITED FROM: Cell Transformation, Neoplastic
L domain-like	0.46	INHERITED FROM: Biliary Tract Neoplasms || Gallbladder Neoplasms
MHC antigen-recognition domain	0.4665	INHERITED FROM: Pharyngeal Neoplasms || Oropharyngeal Neoplasms || Otorhinolaryngologic Neoplasms
Plexin repeat	0.4665	INHERITED FROM: Endometrial Neoplasms
Immunoglobulin	0.5031	INHERITED FROM: Oropharyngeal Neoplasms
NAD(P)-linked oxidoreductase	0.5088	INHERITED FROM: Uterine Neoplasms || Neoplasms, Hormone-Dependent || Endometrial Neoplasms || Cell Transformation, Neoplastic || Ovarian Cysts || Polycystic Ovary Syndrome || Cysts || Genital Neoplasms, Female
Ankyrin repeat	0.5284	INHERITED FROM: Neoplasms, Ductal, Lobular, and Medullary
Clc chloride channel	0.65	INHERITED FROM: Neoplasms, Neuroepithelial || Glioma
ARM repeat	0.6635	INHERITED FROM: Adenocarcinoma Of Esophagus
Sema domain	0.7508	INHERITED FROM: Endometrial Neoplasms || Genital Neoplasms, Female
FAD/NAD(P)-binding domain	0.9792	INHERITED FROM: Paraganglioma

Supra-domain (Duplex) in N- to C-terminal order

Highlighted in gray are those with FDR>0.001

Supra-domain (Duplex) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
57903,57903 57903 - FYVE/PHD zinc finger 57903 - FYVE/PHD zinc finger	0	DIRECT
48371,-7 48371 - ARM repeat -7 - CATH	0	DIRECT
54236,57889 54236 - Ubiquitin-like 57889 - Cysteine-rich domain	0	DIRECT
90193,90193 90193 - Notch domain 90193 - Notch domain	0	DIRECT
49417,47719 49417 - p53-like transcription factors 47719 - p53 tetramerization domain	0	DIRECT
50729,55550 50729 - PH domain-like 55550 - SH2 domain	0	DIRECT
117839,117839 117839 - WWE domain 117839 - WWE domain	0	DIRECT
49562,48371 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat	0	DIRECT
100895,100895 100895 - Kazal-type serine protease inhibitors 100895 - Kazal-type serine protease inhibitors	0	DIRECT
53850,53850 53850 - Periplasmic binding protein-like II 53850 - Periplasmic binding protein-like II	0	DIRECT
48371,56112 48371 - ARM repeat 56112 - Protein kinase-like (PK-like)	0	DIRECT
-7,56112 -7 - CATH 56112 - Protein kinase-like (PK-like)	0	DIRECT
53732,52016 53732 - Aconitase iron-sulfur domain 52016 - LeuD/IlvD-like	0	DIRECT
103473,100895 103473 - MFS general substrate transporter 100895 - Kazal-type serine protease inhibitors	0	DIRECT
49562,48350 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48350 - GTPase activation domain, GAP	0	DIRECT
47459,158457 47459 - HLH, helix-loop-helix DNA-binding domain 158457 - Orange domain-like	0	DIRECT
57924,57924 57924 - Inhibitor of apoptosis (IAP) repeat 57924 - Inhibitor of apoptosis (IAP) repeat	0	DIRECT
52058,52047 52058 - L domain-like 52047 - RNI-like	0	DIRECT
48334,52540 48334 - DNA repair protein MutS, domain III 52540 - P-loop containing nucleoside triphosphate hydrolases	0	DIRECT
57196,90193 57196 - EGF/Laminin 90193 - Notch domain	0	DIRECT
46579,64593 46579 - Prefoldin 64593 - Intermediate filament protein, coiled coil region	0	DIRECT
55550,158235 55550 - SH2 domain 158235 - SOCS box-like	0	DIRECT
55874,54211 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 54211 - Ribosomal protein S5 domain 2-like	0	DIRECT
57184,49265 57184 - Growth factor receptor domain 49265 - Fibronectin type III	0	DIRECT
47095,47095 47095 - HMG-box 47095 - HMG-box	0	DIRECT
90123,52540 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases	0.001562	INHERITED FROM: Digestive System Neoplasms || Colorectal Neoplasms || Neoplasms by Site || Gastrointestinal Neoplasms || Squamous Cell Carcinoma of Head and Neck || Intestinal Neoplasms
57196,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain	0.002712	INHERITED FROM: Neoplasms, Ductal, Lobular, and Medullary || Astrocytoma || Carcinoma, Ductal || Pancreatic Neoplasms || Endocrine Gland Neoplasms || Carcinoma, Pancreatic Ductal || Neuroectodermal Tumors || Skin Neoplasms || Glioma
47954,47954 47954 - Cyclin-like 47954 - Cyclin-like	0.004647	INHERITED FROM: Head and Neck Neoplasms || Neoplasms by Histologic Type || Carcinoma || Neoplasms, Squamous Cell || Squamous Cell Carcinoma of Head and Neck || Genital Neoplasms, Female
52540,90123 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region	0.005441	INHERITED FROM: Colorectal Neoplasms || Gastrointestinal Neoplasms || Intestinal Neoplasms
47090,55486 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain	0.007624	INHERITED FROM: Colorectal Neoplasms || Astrocytoma || Neoplastic Processes
63748,63748 63748 - Tudor/PWWP/MBT 63748 - Tudor/PWWP/MBT	0.009938	INHERITED FROM: Medulloblastoma || Neoplasms, Nerve Tissue || Neoplasms, Germ Cell and Embryonal || Neoplasms by Histologic Type || Neoplasms, Neuroepithelial || Neuroectodermal Tumors || Glioma || Melanoma
52283,51735 52283 - Formate/glycerate dehydrogenase catalytic domain-like 51735 - NAD(P)-binding Rossmann-fold domains	0.01801	INHERITED FROM: Prostatic Neoplasms || Genital Neoplasms, Male
48092,47655 48092 - Transcription factor STAT-4 N-domain 47655 - STAT	0.01801	INHERITED FROM: Precursor Cell Lymphoblastic Leukemia-Lymphoma || Leukemia, Lymphoid
47655,49417 47655 - STAT 49417 - p53-like transcription factors	0.01801	INHERITED FROM: Precursor Cell Lymphoblastic Leukemia-Lymphoma || Leukemia, Lymphoid
49417,55550 49417 - p53-like transcription factors 55550 - SH2 domain	0.01801	INHERITED FROM: Precursor Cell Lymphoblastic Leukemia-Lymphoma || Leukemia, Lymphoid
55785,55785 55785 - PYP-like sensor domain (PAS domain) 55785 - PYP-like sensor domain (PAS domain)	0.01801	INHERITED FROM: Prostatic Neoplasms || Breast Neoplasms
57184,52058 57184 - Growth factor receptor domain 52058 - L domain-like	0.01801	INHERITED FROM: Pharyngeal Neoplasms || Nasopharyngeal Neoplasms || Otorhinolaryngologic Neoplasms || Biliary Tract Neoplasms || Gallbladder Neoplasms
52058,57184 52058 - L domain-like 57184 - Growth factor receptor domain	0.01801	INHERITED FROM: Pharyngeal Neoplasms || Nasopharyngeal Neoplasms || Otorhinolaryngologic Neoplasms || Biliary Tract Neoplasms || Gallbladder Neoplasms
54160,54160 54160 - Chromo domain-like 54160 - Chromo domain-like	0.02123	INHERITED FROM: Prostatic Neoplasms
47459,55785 47459 - HLH, helix-loop-helix DNA-binding domain 55785 - PYP-like sensor domain (PAS domain)	0.03224	INHERITED FROM: Breast Neoplasms
57440,50494 57440 - Kringle-like 50494 - Trypsin-like serine proteases	0.03513	INHERITED FROM: Neoplasm Metastasis
57440,57440 57440 - Kringle-like 57440 - Kringle-like	0.03513	INHERITED FROM: Carcinoma, Hepatocellular || Astrocytoma || Carcinoma || Neoplastic Processes || Neoplasms, Experimental || Glioma
52058,48726 52058 - L domain-like 48726 - Immunoglobulin	0.05757	INHERITED FROM: Neoplasms, Neuroepithelial || Neuroectodermal Tumors || Glioma
55550,50044 55550 - SH2 domain 50044 - SH3-domain	0.05757	INHERITED FROM: Leukemia, Lymphoid
51735,50129 51735 - NAD(P)-binding Rossmann-fold domains 50129 - GroES-like	0.05757	INHERITED FROM: Mouth Neoplasms
63501,50242 63501 - Frizzled cysteine-rich domain 50242 - TIMP-like	0.05757	INHERITED FROM: Colorectal Neoplasms || Gastrointestinal Neoplasms || Intestinal Neoplasms
48552,48552 48552 - Serum albumin-like 48552 - Serum albumin-like	0.05757	INHERITED FROM: Stomach Neoplasms
46785,144074 46785 - "Winged helix" DNA-binding domain 144074 - E2F-DP heterodimerization region	0.05816	INHERITED FROM: Carcinoma, Non-Small-Cell Lung || Lung Neoplasms || Respiratory Tract Neoplasms || Thoracic Neoplasms
50729,56112 50729 - PH domain-like 56112 - Protein kinase-like (PK-like)	0.05816	INHERITED FROM: Head and Neck Neoplasms
57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin	0.06058	INHERITED FROM: Neoplasms, Ductal, Lobular, and Medullary || Astrocytoma || Carcinoma, Ductal || Carcinoma, Pancreatic Ductal || Glioma
52833,52833 52833 - Thioredoxin-like 52833 - Thioredoxin-like	0.07986	INHERITED FROM: Prostatic Neoplasms || Genital Neoplasms, Male
47986,47986 47986 - DEATH domain 47986 - DEATH domain	0.09588	INHERITED FROM: Stomach Neoplasms
50729,49562 50729 - PH domain-like 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)	0.1036	INHERITED FROM: Prostatic Neoplasms || Genital Neoplasms, Male
49899,57196 49899 - Concanavalin A-like lectins/glucanases 57196 - EGF/Laminin	0.1121	INHERITED FROM: Esophageal Neoplasms || Esophageal Squamous Cell Carcinoma
81296,81296 81296 - E set domains 81296 - E set domains	0.1427	INHERITED FROM: Sarcoma
57184,57184 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain	0.1718	INHERITED FROM: Neoplasms, Neuroepithelial || Astrocytoma || Glioblastoma || Glioma
53300,69318 53300 - vWA-like 69318 - Integrin alpha N-terminal domain	0.2418	INHERITED FROM: Leukemia, Promyelocytic, Acute || Leukemia, Myeloid, Acute || Leukemia || Leukemia, Myeloid
69179,69179 69179 - Integrin domains 69179 - Integrin domains	0.3105	INHERITED FROM: Leukemia, Promyelocytic, Acute
69318,69179 69318 - Integrin alpha N-terminal domain 69179 - Integrin domains	0.3105	INHERITED FROM: Leukemia, Promyelocytic, Acute
54452,48726 54452 - MHC antigen-recognition domain 48726 - Immunoglobulin	0.3222	INHERITED FROM: Pharyngeal Neoplasms || Oropharyngeal Neoplasms || Otorhinolaryngologic Neoplasms
57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers	0.3289	INHERITED FROM: Adenocarcinoma, Papillary || Thyroid Cancer, Papillary
57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain)	0.373	INHERITED FROM: Leukemia, T-Cell
55550,56112 55550 - SH2 domain 56112 - Protein kinase-like (PK-like)	0.399	INHERITED FROM: Leukemia
57184,57196 57184 - Growth factor receptor domain 57196 - EGF/Laminin	0.4799	INHERITED FROM: Neoplasms, Ductal, Lobular, and Medullary || Carcinoma, Ductal || Carcinoma, Pancreatic Ductal
101912,103575 101912 - Sema domain 103575 - Plexin repeat	0.7508	INHERITED FROM: Endometrial Neoplasms || Genital Neoplasms, Female

Supra-domain (Triple) in N- to C-terminal order

Highlighted in gray are those with FDR>0.001

Supra-domain (Triple) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
47986,47986,52129 47986 - DEATH domain 47986 - DEATH domain 52129 - Caspase-like	0	DIRECT
57196,57196,90193 57196 - EGF/Laminin 57196 - EGF/Laminin 90193 - Notch domain	0	DIRECT
100895,100895,100895 100895 - Kazal-type serine protease inhibitors 100895 - Kazal-type serine protease inhibitors 100895 - Kazal-type serine protease inhibitors	0	DIRECT
49785,57184,49265 49785 - Galactose-binding domain-like 57184 - Growth factor receptor domain 49265 - Fibronectin type III	0	DIRECT
49562,48371,56112 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat 56112 - Protein kinase-like (PK-like)	0	DIRECT
55550,56112,56112 55550 - SH2 domain 56112 - Protein kinase-like (PK-like) 56112 - Protein kinase-like (PK-like)	0	DIRECT
52058,48726,48726 52058 - L domain-like 48726 - Immunoglobulin 48726 - Immunoglobulin	0	DIRECT
50729,55550,56112 50729 - PH domain-like 55550 - SH2 domain 56112 - Protein kinase-like (PK-like)	0	DIRECT
54791,54791,54791 54791 - Eukaryotic type KH-domain (KH-domain type I) 54791 - Eukaryotic type KH-domain (KH-domain type I) 54791 - Eukaryotic type KH-domain (KH-domain type I)	0	DIRECT
49503,49503,49503 49503 - Cupredoxins 49503 - Cupredoxins 49503 - Cupredoxins	0	DIRECT
57924,57924,57924 57924 - Inhibitor of apoptosis (IAP) repeat 57924 - Inhibitor of apoptosis (IAP) repeat 57924 - Inhibitor of apoptosis (IAP) repeat	0	DIRECT
57184,52058,57184 57184 - Growth factor receptor domain 52058 - L domain-like 57184 - Growth factor receptor domain	0	DIRECT
90123,52540,90123 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region	0.005441	INHERITED FROM: Colorectal Neoplasms || Gastrointestinal Neoplasms || Intestinal Neoplasms
52540,90123,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases	0.005441	INHERITED FROM: Colorectal Neoplasms || Gastrointestinal Neoplasms || Intestinal Neoplasms
47655,49417,55550 47655 - STAT 49417 - p53-like transcription factors 55550 - SH2 domain	0.01801	INHERITED FROM: Precursor Cell Lymphoblastic Leukemia-Lymphoma || Leukemia, Lymphoid
48092,47655,49417 48092 - Transcription factor STAT-4 N-domain 47655 - STAT 49417 - p53-like transcription factors	0.01801	INHERITED FROM: Precursor Cell Lymphoblastic Leukemia-Lymphoma || Leukemia, Lymphoid
52058,57184,52058 52058 - L domain-like 57184 - Growth factor receptor domain 52058 - L domain-like	0.01801	INHERITED FROM: Pharyngeal Neoplasms || Nasopharyngeal Neoplasms || Otorhinolaryngologic Neoplasms || Biliary Tract Neoplasms || Gallbladder Neoplasms
47459,55785,55785 47459 - HLH, helix-loop-helix DNA-binding domain 55785 - PYP-like sensor domain (PAS domain) 55785 - PYP-like sensor domain (PAS domain)	0.01801	INHERITED FROM: Prostatic Neoplasms || Breast Neoplasms
57184,57196,57184 57184 - Growth factor receptor domain 57196 - EGF/Laminin 57184 - Growth factor receptor domain	0.03209	INHERITED FROM: Neoplasms, Squamous Cell || Carcinoma, Squamous Cell || Skin Neoplasms
57440,57440,57440 57440 - Kringle-like 57440 - Kringle-like 57440 - Kringle-like	0.03209	INHERITED FROM: Carcinoma, Hepatocellular || Astrocytoma || Neoplasm Metastasis || Neoplastic Processes || Glioma
57196,57184,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain	0.03513	INHERITED FROM: Neoplasms, Ductal, Lobular, and Medullary || Astrocytoma || Carcinoma, Ductal || Pancreatic Neoplasms || Glioblastoma || Skin Neoplasms || Glioma || Intestinal Neoplasms
50129,51735,50129 50129 - GroES-like 51735 - NAD(P)-binding Rossmann-fold domains 50129 - GroES-like	0.05757	INHERITED FROM: Mouth Neoplasms
52833,52833,52833 52833 - Thioredoxin-like 52833 - Thioredoxin-like 52833 - Thioredoxin-like	0.1221	INHERITED FROM: Prostatic Neoplasms || Genital Neoplasms, Male
57196,57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin 57196 - EGF/Laminin	0.1345	INHERITED FROM: Neoplasms, Ductal, Lobular, and Medullary || Neoplasms, Neuroepithelial || Astrocytoma || Carcinoma, Ductal || Pancreatic Neoplasms || Carcinoma, Pancreatic Ductal || Glioblastoma || Skin Neoplasms || Glioma
57196,57184,57196 57196 - EGF/Laminin 57184 - Growth factor receptor domain 57196 - EGF/Laminin	0.2066	INHERITED FROM: Neoplasms, Ductal, Lobular, and Medullary || Astrocytoma || Carcinoma, Ductal || Carcinoma, Pancreatic Ductal || Glioblastoma || Glioma
57196,57196,57184 57196 - EGF/Laminin 57196 - EGF/Laminin 57184 - Growth factor receptor domain	0.2344	INHERITED FROM: Neoplasms, Nerve Tissue || Neoplasms, Ductal, Lobular, and Medullary || Neoplasms, Germ Cell and Embryonal || Neoplasms, Neuroepithelial || Astrocytoma || Carcinoma, Ductal || Pancreatic Neoplasms || Breast Neoplasms || Endocrine Gland Neoplasms || Esophageal Squamous Cell Carcinoma || Carcinoma, Pancreatic Ductal || Neuroectodermal Tumors || Skin Neoplasms || Glioma
53300,69318,69179 53300 - vWA-like 69318 - Integrin alpha N-terminal domain 69179 - Integrin domains	0.2418	INHERITED FROM: Leukemia, Promyelocytic, Acute || Leukemia, Myeloid, Acute || Leukemia || Leukemia, Myeloid
81296,81296,81296 81296 - E set domains 81296 - E set domains 81296 - E set domains	0.2909	INHERITED FROM: Neoplasms, Connective and Soft Tissue || Neoplasms, Connective Tissue || Sarcoma
69318,69179,69179 69318 - Integrin alpha N-terminal domain 69179 - Integrin domains 69179 - Integrin domains	0.3105	INHERITED FROM: Leukemia, Promyelocytic, Acute
49899,57196,57196 49899 - Concanavalin A-like lectins/glucanases 57196 - EGF/Laminin 57196 - EGF/Laminin	0.3971	INHERITED FROM: Esophageal Neoplasms || Esophageal Squamous Cell Carcinoma
57667,57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers	0.4577	INHERITED FROM: Gastrointestinal Stromal Tumors