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CTD Chemicals (CC): Nucleic Acids, Nucleotides, and Nucleosides 

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Root: CC Hierarchy (CTD chemicals from Comparative Toxicogenomics Database)

Shortest distance to current term
(+ for parents, - for children)		 CC term [CC ID] <#Children> #Domains
(Superfamily|Family)		 #Supra-domain
(Single|Duplex|Triple)
+ 1:   Chemicals [MESH:D] <13>
0:   Nucleic Acids, Nucleotides, and Nucleosides [MESH:D009706] <2>(102|135) (111|70|25)
- 1:   Nucleosides [MESH:D009705] <138>(75|110) (83|57|23)
- 1:   Nucleotides [MESH:D009711] <57>(42|48) (45|17|2)

Superfamily

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Superfamily

(show details)
SCOP term FDR (all) Annotation (direct or inherited)
SIS domain0Direct
beta-lactamase/transpeptidase-like0Direct
MOSC N-terminal domain-like0Direct
Nucleoplasmin-like core domain0Direct
P-domain of calnexin/calreticulin0Direct
AhpD-like0Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain0Direct
Uracil-DNA glycosylase-like0Direct
Nop domain0Direct
FMT C-terminal domain-like0Direct
beta-beta-alpha zinc fingers0Direct
Fibrinogen coiled-coil and central regions0Direct
HSP90 C-terminal domain0Direct
PWI domain0Direct
SPOC domain-like0Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
NAD(P)-binding Rossmann-fold domains0.00000000000001094Direct
KRAB domain (Kruppel-associated box)0.000000001091Direct
Leucine zipper domain0.0000008033Direct
Nuclear receptor ligand-binding domain0.000002773Direct
Bromodomain0.00003591Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.00004249Direct
Growth factor receptor domain0.00004665Direct
Thyroglobulin type-1 domain0.0001303Direct
Retrovirus capsid dimerization domain-like0.000157Direct
HMG-box0.0001571Direct
ALDH-like0.0002117Direct
DNA/RNA polymerases0.0002981Direct
Caspase-like0.0006702Direct
Glucocorticoid receptor-like (DNA-binding domain)0.0008533Direct
Cytochrome P4500.001134Inherited
SCOP hierarchy in SUPERFAMILY0.001456Inherited
Nucleic acid-binding proteins0.001711Inherited
Tubulin C-terminal domain-like0.001834Inherited
DNA-binding domain0.002007Inherited
A DNA-binding domain in eukaryotic transcription factors0.002098Inherited
Cyclin-like0.002417Inherited
Ribosomal protein S5 domain 2-like0.004252Inherited
P-loop containing nucleoside triphosphate hydrolases0.005185Inherited
NAD(P)-linked oxidoreductase0.005272Inherited
Metallothionein0.006849Inherited
"Winged helix" DNA-binding domain0.007631Inherited
TB module/8-cys domain0.0101Inherited
post-AAA+ oligomerization domain-like0.01224Inherited
SAP domain0.01248Inherited
RNA-binding domain, RBD0.01307Inherited
ARID-like0.01902Inherited
ABC transporter transmembrane region0.02039Inherited
BRCT domain0.02118Inherited
Nuclear receptor coactivator interlocking domain0.02856Inherited
PK beta-barrel domain-like0.02856Inherited
FnI-like domain0.02858Inherited
Cystine-knot cytokines0.03074Inherited
Bcl-2 inhibitors of programmed cell death0.03447Inherited
Tudor/PWWP/MBT0.04179Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.04465Inherited
S15/NS1 RNA-binding domain0.04465Inherited
HD-domain/PDEase-like0.05123Inherited
GINS helical bundle-like0.06429Inherited
Domain of poly(ADP-ribose) polymerase0.06429Inherited
PurM N-terminal domain-like0.06429Inherited
PurM C-terminal domain-like0.06429Inherited
DEATH domain0.06724Inherited
MHC antigen-recognition domain0.07108Inherited
PYP-like sensor domain (PAS domain)0.08202Inherited
MFS general substrate transporter0.08318Inherited
4-helical cytokines0.08704Inherited
Inhibitor of apoptosis (IAP) repeat0.09892Inherited
Cytochrome b5-like heme/steroid binding domain0.09962Inherited
Integrin domains0.1081Inherited
Nudix0.1333Inherited
EGF/Laminin0.1523Inherited
SpoIIaa-like0.165Inherited
Serpins0.1687Inherited
Ferritin-like0.1735Inherited
LuxS/MPP-like metallohydrolase0.1735Inherited
Mitochondrial carrier0.1747Inherited
FYVE/PHD zinc finger0.2014Inherited
SMAD/FHA domain0.218Inherited
Translation proteins SH3-like domain0.2209Inherited
PGBD-like0.249Inherited
Flavoproteins0.2548Inherited
Protein kinase-like (PK-like)0.2631Inherited
Interleukin 8-like chemokines0.2867Inherited
PIN domain-like0.3171Inherited
FAD/NAD(P)-binding domain0.3232Inherited
Cation efflux protein transmembrane domain-like0.344Inherited
Hemopexin-like domain0.346Inherited
Nucleotidylyl transferase0.4053Inherited
SNF-like0.4055Inherited
ADP-ribosylation0.407Inherited
Proton glutamate symport protein0.4108Inherited
TNF receptor-like0.5649Inherited
Fibrinogen C-terminal domain-like0.5681Inherited
Fibronectin type III0.6517Inherited
Toll/Interleukin receptor TIR domain0.6824Inherited
FAD-linked reductases, C-terminal domain0.759Inherited
POZ domain0.8027Inherited
HSP20-like chaperones0.9821Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.9902Inherited
Metalloproteases ("zincins"), catalytic domain1Inherited
PH domain-like1Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

Family

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Family

(show details)
SCOP term FDR (all) Annotation (direct or inherited)
alpha-ketoacid dehydrogenase kinase, N-terminal domain0Direct
C5 cytosine-specific DNA methylase, DCM0Direct
TRASH domain0Direct
IP3 receptor type 1 binding core, domain 20Direct
Heat shock protein 90, HSP90, N-terminal domain0Direct
MOSC N-terminal domain-like0Direct
Methyl-CpG-binding domain, MBD0Direct
DEATH effector domain, DED0Direct
PWI domain0Direct
Lesion bypass DNA polymerase (Y-family), catalytic domain0Direct
P-domain of calnexin/calreticulin0Direct
HSP90 C-terminal domain0Direct
Fibrinogen coiled-coil and central regions0Direct
alpha-ketoacid dehydrogenase kinase, C-terminal domain0Direct
SPOC domain0Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
Cystathionine synthase-like0Direct
Retinoblastoma tumor suppressor domains0Direct
Biotin dependent carboxylase carboxyltransferase domain0Direct
Calnexin/calreticulin0Direct
Hsp90 middle domain0Direct
Nucleoplasmin-like core domain0Direct
Nop domain0Direct
Ferredoxin domains from multidomain proteins0Direct
Variant RING domain0Direct
Tyrosine-dependent oxidoreductases0Direct
Splicing factor U2AF subunits0Direct
Classic zinc finger, C2H20.00000000000001845Direct
KRAB domain (Kruppel-associated box)0.0000002546Direct
Nuclear receptor0.000001081Direct
Leucine zipper domain0.000001894Direct
Tandem AAA-ATPase domain0.00000567Direct
Nuclear receptor ligand-binding domain0.000005981Direct
Bromodomain0.00006673Direct
Thyroglobulin type-1 domain0.0001692Direct
ALDH-like0.0002823Direct
HMG-box0.0003048Direct
SCAN domain0.0003151Direct
Caspase catalytic domain0.000443Direct
PWWP domain0.0006016Direct
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.001791Inherited
Tubulin, C-terminal domain0.002471Inherited
A DNA-binding domain in eukaryotic transcription factors0.002584Inherited
Growth factor receptor domain0.002948Inherited
Cytochrome P4500.003261Inherited
Short-chain cytokines0.003783Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.005085Inherited
PHD domain0.006084Inherited
Cold shock DNA-binding domain-like0.006202Inherited
Aldo-keto reductases (NADP)0.006433Inherited
Metallothionein0.007819Inherited
Cyclin0.009942Inherited
Interferon regulatory factor0.01097Inherited
TB module/8-cys domain0.01097Inherited
DNA gyrase/MutL, N-terminal domain0.01265Inherited
DNA gyrase/MutL, second domain0.01265Inherited
Glutathione peroxidase-like0.01356Inherited
Cell cycle transcription factor e2f-dp0.0157Inherited
SAP domain0.01595Inherited
ABC transporter ATPase domain-like0.01919Inherited
MutT-like0.02207Inherited
ARID domain0.02207Inherited
DNA replication initiator (cdc21/cdc54) N-terminal domain0.02306Inherited
ABC transporter transmembrane region0.0263Inherited
Nuclear receptor coactivator interlocking domain0.02895Inherited
a tRNA synthase domain0.02895Inherited
Cytochrome b50.0305Inherited
Bcl-2 inhibitors of programmed cell death0.03902Inherited
L domain0.04668Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.04668Inherited
Glycerol-3-phosphate transporter0.04668Inherited
DNA polymerase I0.04668Inherited
C2 set domains0.05709Inherited
Domain of poly(ADP-ribose) polymerase0.06395Inherited
2'-5'-oligoadenylate synthetase 1, OAS1, second domain0.06395Inherited
2'-5'-oligoadenylate synthetase 1, OAS1, N-terminal domain0.06395Inherited
Tetrahydrofolate dehydrogenase/cyclohydrolase0.06395Inherited
GS domain0.06395Inherited
PurM C-terminal domain-like0.06395Inherited
PurM N-terminal domain-like0.06395Inherited
XPF/Rad1/Mus81 nuclease0.06395Inherited
Enolase0.06395Inherited
PDEase0.06572Inherited
FAD/NAD-linked reductases, N-terminal and central domains0.06646Inherited
Phoshoinositide 3-kinase (PI3K), catalytic domain0.06783Inherited
S100 proteins0.06792Inherited
DEATH domain, DD0.08336Inherited
MHC antigen-recognition domain0.08965Inherited
GABARAP-like0.09027Inherited
Frizzled cysteine-rich domain0.09949Inherited
Platelet-derived growth factor-like0.1026Inherited
Inhibitor of apoptosis (IAP) repeat0.1026Inherited
Double-stranded RNA-binding domain (dsRBD)0.1031Inherited
Transforming growth factor (TGF)-beta0.1219Inherited
C1 set domains (antibody constant domain-like)0.1219Inherited
Integrin domains0.1251Inherited
Myb/SANT domain0.1251Inherited
Canonical RBD0.1324Inherited
Serpins0.1622Inherited
PDI-like0.1673Inherited
Long-chain cytokines0.1673Inherited
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains0.1729Inherited
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain0.1729Inherited
Extended AAA-ATPase domain0.1762Inherited
MPP-like0.1764Inherited
Mitochondrial carrier0.1851Inherited
BTB/POZ domain0.2226Inherited
Matrix metalloproteases, catalytic domain0.2359Inherited
Cation efflux protein transmembrane domain-like0.263Inherited
MMP N-terminal domain0.2686Inherited
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.311Inherited
Interleukin 8-like chemokines0.3313Inherited
Gonadodropin/Follitropin0.3537Inherited
Hemopexin-like domain0.3732Inherited
TNF receptor-like0.3997Inherited
FAD-linked reductases, N-terminal domain0.4136Inherited
RecA protein-like (ATPase-domain)0.4136Inherited
Proton glutamate symport protein0.414Inherited
STAT0.414Inherited
Transcription factor STAT-4 N-domain0.414Inherited
Poly(ADP-ribose) polymerase, C-terminal domain0.414Inherited
STAT DNA-binding domain0.414Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.428Inherited
SNF-like0.428Inherited
Protein kinases, catalytic subunit0.5648Inherited
PAPS sulfotransferase0.5944Inherited
Fibrinogen C-terminal domain-like0.6072Inherited
G proteins0.6137Inherited
FHA domain0.7269Inherited
Toll/Interleukin receptor TIR domain0.7499Inherited
Fibronectin type III0.782Inherited
cAMP-binding domain0.818Inherited
Pyrin domain, PYD0.9163Inherited
Interferons/interleukin-10 (IL-10)0.971Inherited
Pleckstrin-homology domain (PH domain)1Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

Supra-domain (Single|Duplex|Triple)

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Supra-domain (Single)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
FMT C-terminal domain-like0Direct
Nop domain0Direct
AhpD-like0Direct
P-domain of calnexin/calreticulin0Direct
PWI domain0Direct
SPOC domain-like0Direct
Nucleoplasmin-like core domain0Direct
MOSC N-terminal domain-like0Direct
HSP90 C-terminal domain0Direct
SIS domain0Direct
Uracil-DNA glycosylase-like0Direct
Fibrinogen coiled-coil and central regions0Direct
beta-lactamase/transpeptidase-like0Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
beta-beta-alpha zinc fingers0Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain0Direct
NAD(P)-binding Rossmann-fold domains0.00000000000000423Direct
KRAB domain (Kruppel-associated box)0.0000000004469Direct
Leucine zipper domain0.0000003681Direct
Nuclear receptor ligand-binding domain0.000001312Direct
Bromodomain0.00001847Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.00002198Direct
Growth factor receptor domain0.00002422Direct
Thyroglobulin type-1 domain0.00007063Direct
Retrovirus capsid dimerization domain-like0.00008586Direct
HMG-box0.00008591Direct
ALDH-like0.0001172Direct
DNA/RNA polymerases0.0001676Direct
Caspase-like0.0003922Direct
Glucocorticoid receptor-like (DNA-binding domain)0.0005051Direct
Cytochrome P4500.0006814Direct
Nucleic acid-binding proteins0.00105Inherited
Tubulin C-terminal domain-like0.00113Inherited
DNA-binding domain0.001242Inherited
A DNA-binding domain in eukaryotic transcription factors0.001301Inherited
Cyclin-like0.001508Inherited
Ribosomal protein S5 domain 2-like0.002734Inherited
P-loop containing nucleoside triphosphate hydrolases0.003363Inherited
NAD(P)-linked oxidoreductase0.003422Inherited
Metallothionein0.004519Inherited
"Winged helix" DNA-binding domain0.005068Inherited
TB module/8-cys domain0.006812Inherited
post-AAA+ oligomerization domain-like0.008345Inherited
SAP domain0.008521Inherited
RNA-binding domain, RBD0.008943Inherited
ARID-like0.01332Inherited
ABC transporter transmembrane region0.01434Inherited
BRCT domain0.01492Inherited
PK beta-barrel domain-like0.02045Inherited
Nuclear receptor coactivator interlocking domain0.02045Inherited
Chromo domain-like0.02047Inherited
FnI-like domain0.02047Inherited
Cystine-knot cytokines0.02213Inherited
Bcl-2 inhibitors of programmed cell death0.02498Inherited
Tudor/PWWP/MBT0.03059Inherited
S15/NS1 RNA-binding domain0.03282Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.03282Inherited
HD-domain/PDEase-like0.03799Inherited
GINS helical bundle-like0.04819Inherited
PurM C-terminal domain-like0.04819Inherited
PurM N-terminal domain-like0.04819Inherited
Domain of poly(ADP-ribose) polymerase0.04819Inherited
DEATH domain0.05056Inherited
MHC antigen-recognition domain0.05364Inherited
PYP-like sensor domain (PAS domain)0.06239Inherited
MFS general substrate transporter0.06327Inherited
4-helical cytokines0.06634Inherited
Frizzled cysteine-rich domain0.06664Inherited
Inhibitor of apoptosis (IAP) repeat0.076Inherited
Cytochrome b5-like heme/steroid binding domain0.07658Inherited
Integrin domains0.08339Inherited
Nudix0.1042Inherited
EGF/Laminin0.1199Inherited
SpoIIaa-like0.1306Inherited
Serpins0.1338Inherited
LuxS/MPP-like metallohydrolase0.1378Inherited
Ferritin-like0.1378Inherited
Mitochondrial carrier0.1389Inherited
FYVE/PHD zinc finger0.1619Inherited
SMAD/FHA domain0.1762Inherited
Translation proteins SH3-like domain0.1787Inherited
PGBD-like0.2032Inherited
Flavoproteins0.2082Inherited
Protein kinase-like (PK-like)0.2156Inherited
VHP, Villin headpiece domain0.2234Inherited
Interleukin 8-like chemokines0.2362Inherited
PIN domain-like0.2635Inherited
FAD/NAD(P)-binding domain0.2692Inherited
Cation efflux protein transmembrane domain-like0.2881Inherited
Hemopexin-like domain0.29Inherited
Nucleotidylyl transferase0.3437Inherited
SNF-like0.3439Inherited
Ribonuclease H-like0.3446Inherited
ADP-ribosylation0.3453Inherited
Proton glutamate symport protein0.3489Inherited
STAT0.3489Inherited
Transcription factor STAT-4 N-domain0.3489Inherited
TNF receptor-like0.4942Inherited
Fibrinogen C-terminal domain-like0.4975Inherited
Chaperone J-domain0.5394Inherited
Fibronectin type III0.58Inherited
Toll/Interleukin receptor TIR domain0.6106Inherited
FAD-linked reductases, C-terminal domain0.6878Inherited
PAP/OAS1 substrate-binding domain0.7327Inherited
POZ domain0.7337Inherited
TSP-1 type 1 repeat0.743Inherited
HSP20-like chaperones0.9281Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.9373Inherited
RING/U-box0.9859Inherited
Metalloproteases ("zincins"), catalytic domain0.9918Inherited
PH domain-like1Inherited

LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm

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Supra-domain (Duplex) in N- to C-terminal order

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
100934,100934
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
    		• 0Direct
    57414,57440
  • 57414 - Hairpin loop containing domain-like
  • 57440 - Kringle-like
    		• 0Direct
    56672,100879
  • 56672 - DNA/RNA polymerases
  • 100879 - Lesion bypass DNA polymerase (Y-family), little finger domain
    		• 0Direct
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
    		• 0Direct
    47986,52129
  • 47986 - DEATH domain
  • 52129 - Caspase-like
    		• 0Direct
    141673,50800
  • 141673 - MOSC N-terminal domain-like
  • 50800 - PK beta-barrel domain-like
    		• 0Direct
    47781,47781
  • 47781 - RuvA domain 2-like
  • 47781 - RuvA domain 2-like
    		• 0Direct
    81698,81698
  • 81698 - FF domain
  • 81698 - FF domain
    		• 0Direct
    55021,56534
  • 55021 - ACT-like
  • 56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains
    		• 0Direct
    54826,51604
  • 54826 - Enolase N-terminal domain-like
  • 51604 - Enolase C-terminal domain-like
    		• 0Direct
    49899,63887
  • 49899 - Concanavalin A-like lectins/glucanases
  • 63887 - P-domain of calnexin/calreticulin
    		• 0Direct
    53328,50486
  • 53328 - Formyltransferase
  • 50486 - FMT C-terminal domain-like
    		• 0Direct
    63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
    		• 0Direct
    69012,55874
  • 69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
    		• 0Direct
    46689,57667
  • 46689 - Homeodomain-like
  • 57667 - beta-beta-alpha zinc fingers
    		• 0Direct
    57667,140996
  • 57667 - beta-beta-alpha zinc fingers
  • 140996 - Hermes dimerisation domain
    		• 0Direct
    57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
    		• 0Direct
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
    		• 0.000002Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
    		• 0.000006142Direct
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
    		• 0.000006757Direct
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
    		• 0.00002609Direct
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
    		• 0.0002737Direct
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
    		• 0.0004922Direct
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
    		• 0.0006421Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
    		• 0.00113Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
    		• 0.001242Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
    		• 0.001308Inherited
    47454,57959
  • 47454 - A DNA-binding domain in eukaryotic transcription factors
  • 57959 - Leucine zipper domain
    		• 0.002787Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
    		• 0.002941Inherited
    47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
    		• 0.003314Inherited
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
    		• 0.003314Inherited
    52540,48019
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48019 - post-AAA+ oligomerization domain-like
    		• 0.008345Inherited
    57184,57610
  • 57184 - Growth factor receptor domain
  • 57610 - Thyroglobulin type-1 domain
    		• 0.008345Inherited
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
    		• 0.008438Inherited
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
    		• 0.01434Inherited
    57184,57603
  • 57184 - Growth factor receptor domain
  • 57603 - FnI-like domain
    		• 0.02045Inherited
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
    		• 0.02045Inherited
    54236,50729
  • 54236 - Ubiquitin-like
  • 50729 - PH domain-like
    		• 0.02045Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
    		• 0.03282Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
    		• 0.03282Inherited
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
    		• 0.03282Inherited
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
    		• 0.03282Inherited
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
    		• 0.03988Inherited
    52821,52799
  • 52821 - Rhodanese/Cell cycle control phosphatase
  • 52799 - (Phosphotyrosine protein) phosphatases II
    		• 0.04361Inherited
    53098,56672
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
    		• 0.04819Inherited
    55326,56042
  • 55326 - PurM N-terminal domain-like
  • 56042 - PurM C-terminal domain-like
    		• 0.04819Inherited
    81995,81811
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
    		• 0.04819Inherited
    53300,81995
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
    		• 0.04819Inherited
    47587,56399
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 56399 - ADP-ribosylation
    		• 0.04819Inherited
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
    		• 0.04855Inherited
    52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
    		• 0.1099Inherited
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
    		• 0.1099Inherited
    46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
    		• 0.1126Inherited
    109640,57667
  • 109640 - KRAB domain (Kruppel-associated box)
  • 57667 - beta-beta-alpha zinc fingers
    		• 0.1217Inherited
    52540,90123
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
    		• 0.1358Inherited
    53901,53901
  • 53901 - Thiolase-like
  • 53901 - Thiolase-like
    		• 0.1358Inherited
    57903,51197
  • 57903 - FYVE/PHD zinc finger
  • 51197 - Clavaminate synthase-like
    		• 0.1378Inherited
    63411,63411
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
    		• 0.1378Inherited
    -7,52540
  • -7 - CATH
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
    		• 0.1378Inherited
    111418,81321
  • 111418 - Hormone receptor domain
  • 81321 - Family A G protein-coupled receptor-like
    		• 0.1787Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
    		• 0.2032Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
    		• 0.2032Inherited
    51206,51206
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
    		• 0.2082Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
    		• 0.3489Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
    		• 0.3489Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
    		• 0.3489Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
    		• 0.3626Inherited
    51905,54373
  • 51905 - FAD/NAD(P)-binding domain
  • 54373 - FAD-linked reductases, C-terminal domain
    		• 0.5582Inherited
    81301,81631
  • 81301 - Nucleotidyltransferase
  • 81631 - PAP/OAS1 substrate-binding domain
    		• 0.7327Inherited
    82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
    		• 0.9343Inherited

    LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm

    Jump to [ Top · Hierarchy ]

    Supra-domain (Triple) in N- to C-terminal order

    (    show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    100895,100895,100895
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
    		• 0Direct
    81698,81698,81698
  • 81698 - FF domain
  • 81698 - FF domain
  • 81698 - FF domain
    		• 0Direct
    57924,57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
    		• 0Direct
    47986,47986,52129
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 52129 - Caspase-like
    		• 0Direct
    57196,57535,57535
  • 57196 - EGF/Laminin
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
    		• 0Direct
    57414,57440,57440
  • 57414 - Hairpin loop containing domain-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
    		• 0Direct
    57196,57581,57196
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
    		• 0Direct
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
    		• 0.00000000000001479Direct
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
    		• 0.0004922Direct
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
    		• 0.0004922Direct
    57184,57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
    		• 0.0004922Direct
    57440,57440,50494
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
    		• 0.008345Inherited
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
    		• 0.02045Inherited
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
    		• 0.03282Inherited
    55550,56112,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
    		• 0.04819Inherited
    53300,81995,81811
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
    		• 0.04819Inherited
    81995,81811,82754
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
    		• 0.04819Inherited
    50729,55550,56112
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
    		• 0.04819Inherited
    52833,52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
    		• 0.1172Inherited
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
    		• 0.1172Inherited
    90123,52540,90123
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
    		• 0.1358Inherited
    52540,90123,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
    		• 0.1358Inherited
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
    		• 0.2234Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
    		• 0.3489Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
    		• 0.3489Inherited

    LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm

    Distribution on sTOL

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    Locations of visitors to this page Using dcGO in your work, please cite Nucleic Acids Research 2013, 41(Database issue):D536-44.
    On questions and detailed information, please contact Dr. Hai Fang or Prof. Julian Gough