NADH oxidase/flavin reductase family

SCOP classification

• Root: SCOP hierarchy in SUPERFAMILY [ 0] (11)
• Class: Alpha and beta proteins (a+b) [ 53931] (376)
• Fold: FMN-dependent nitroreductase-like [ 55468]
• Superfamily: FMN-dependent nitroreductase-like [ 55469] (2)
• Family: NADH oxidase/flavin reductase [ 55470] (8)

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Family statistics

	Genomes (1,361)	Uniprot 2018_03 genome	PDB chains (SCOP 1.75)
Domains	2,260	16,095	13
Proteins	2,260	16,094	13

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Enzyme Commission (EC)

Highlighted in gray are those with FDR_all>0.001

	EC term	FDR (all)	IC level	SDEO level	Annotation (direct or inherited)
Enzyme Commission (EC)	3-hydroxypropionate dehydrogenase (NADP(+))	0	2.741	--	DIRECT
Enzyme Commission (EC)	Acting on halogen in donors	0	2.741	--	DIRECT
Enzyme Commission (EC)	Acting on the CH-OH group of donors	0.00007396	0.935	--	DIRECT
Enzyme Commission (EC)	Oxidoreductases	0	0.3212	Least Informative	DIRECT
Enzyme Commission (EC)	With NAD(+) or NADP(+) as acceptor	0	0.9853	Moderately Informative	DIRECT

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Enzyme Commission (EC)

Highlighted in gray are those with FDR_all>0.001

	EC term	FDR (all)	IC level	SDEC level	Annotation (direct or inherited)
Enzyme Commission (EC)	Aerobic 5,6-dimethylbenzimidazole synthase	0	3.23	--	DIRECT
Enzyme Commission (EC)	Coenzyme F420-1:gamma-L-glutamate ligase	0	2.929	--	DIRECT
Enzyme Commission (EC)	With NAD(+) or NADP(+) as acceptor	0	3.23	--	DIRECT
Enzyme Commission (EC)	Coenzyme F420-0:L-glutamate ligase	0	2.929	--	DIRECT
Enzyme Commission (EC)	3-hydroxypropionate dehydrogenase (NADP(+))	0	3.23	--	DIRECT
Enzyme Commission (EC)	Catalyzing the reaction X-H + Y-H = 'X-Y'	0.0000000002756	2.628	--	DIRECT
Enzyme Commission (EC)	Acting on the CH-OH group of donors	0.0007104	1.372	--	DIRECT
Enzyme Commission (EC)	Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated	0.002593	1.907	--	INHERITED FROM: Aerobic 5,6-dimethylbenzimidazole synthase || With incorporation of two atoms of oxygen
Enzyme Commission (EC)	Oxidoreductases	0	0.7328	Least Informative	DIRECT
Enzyme Commission (EC)	Ligases	0.112	1.14	Moderately Informative	INHERITED FROM: Coenzyme F420-1:gamma-L-glutamate ligase || Acid--amino-acid ligases (peptide synthases) || Coenzyme F420-0:L-glutamate ligase || Forming carbon-nitrogen bonds
Enzyme Commission (EC)	With NAD(+) or NADP(+) as acceptor	0	1.437	Informative	DIRECT
Enzyme Commission (EC)	Forming carbon-nitrogen bonds	0.0005653	1.338	Informative	DIRECT
Enzyme Commission (EC)	Acting on the CH-NH group of donors	0.1076	1.686	Informative	INHERITED FROM: With NAD(+) or NADP(+) as acceptor
Enzyme Commission (EC)	Acid--amino-acid ligases (peptide synthases)	0.00000006814	1.832	Highly Informative	DIRECT
Enzyme Commission (EC)	With incorporation of two atoms of oxygen	0.0000004887	1.974	Highly Informative	DIRECT
Enzyme Commission (EC)	With NAD(+) or NADP(+) as acceptor	0.0001567	1.907	Highly Informative	DIRECT

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