Zebrafish Anatomy (ZA): cavitated compound organ 

Root: ZA Hierarchy (zebrafish anatomy from ZFIN zebrafish anatomy ontology)

Shortest distance to current term (+ for parents, - for children)	ZA term [ZA ID] <#Children>	#Domains (Superfamily|Family)	#Supra-domain (Single|Duplex|Triple)
+ + + + 4:	zebrafish anatomical entity [ZFA:0100000] <6>
+ + 2:	whole organism [ZFA:0001094] <8>	(272|295)	(272|155|71)
+ + 2:	anatomical structure [ZFA:0000037] <16>	(275|296)	(275|157|73)
+ 1:	compound organ [ZFA:0000496] <12>	(96|110)	(100|69|30)
0:	cavitated compound organ [ZFA:0001490] <15>	(78|91)	(80|55|22)
- 1:	brain [ZFA:0000008] <12>	(19|19)	(20|10|7)
- 1:	heart [ZFA:0000114] <12>	(4|5)	(4|2|2)
- 1:	spinal cord [ZFA:0000075] <12>	(3|2)	(4|1|0)
- 1:	eye [ZFA:0000107] <10>	(9|14)	(9|9|5)
- 1:	blood vasculature [ZFA:0001079] <8>	(9|7)	(11|5|1)
- 1:	kidney [ZFA:0000529] <8>	(0|1)	(0|1|0)
- 1:	heart tube [ZFA:0000360] <7>	(0|0)	(0|0|0)
- 1:	intestine [ZFA:0001338] <7>	(1|0)	(1|0|0)
- 1:	atrium [ZFA:0000471] <6>	(0|1)	(0|0|0)
- 1:	cardiac ventricle [ZFA:0000009] <6>	(1|1)	(1|1|1)
- 1:	pronephros [ZFA:0000151] <6>	(1|3)	(1|1|0)
- 1:	otolith organ [ZFA:0000559] <5>	(1|0)	(1|0|0)
- 1:	peripheral olfactory organ [ZFA:0000047] <5>	(0|0)	(0|0|0)
- 1:	swim bladder [ZFA:0000076] <5>	(1|1)	(1|0|0)
- 1:	gonad [ZFA:0000413] <4>	(2|3)	(3|0|0)

Superfamily

Highlighted in gray are those with FDR_all>0.001

SCOP term	FDR (all)	Annotation (direct or inherited)
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	0	DIRECT
Aquaporin-like	0	DIRECT
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	0	DIRECT
F-box domain	0	DIRECT
HIT-like	0	DIRECT
Moesin tail domain	0	DIRECT
ADC-like	0	DIRECT
Cap-Gly domain	0	DIRECT
Tubulin nucleotide-binding domain-like	0	DIRECT
Heat shock protein 70kD (HSP70), peptide-binding domain	0	DIRECT
Translation proteins	0	DIRECT
PLC-like phosphodiesterases	0	DIRECT
Class II aaRS ABD-related	0	DIRECT
Class II aaRS and biotin synthetases	0	DIRECT
Ferredoxin reductase-like, C-terminal NADP-linked domain	0	DIRECT
BRCT domain	0	DIRECT
PP2C-like	0	DIRECT
Cdc48 domain 2-like	0	DIRECT
Ypt/Rab-GAP domain of gyp1p	0	DIRECT
Translational machinery components	0	DIRECT
Single hybrid motif	0	DIRECT
Nuclear receptor coactivator interlocking domain	0	DIRECT
SRF-like	0	DIRECT
LCCL domain	0	DIRECT
Lipovitellin-phosvitin complex, superhelical domain	0	DIRECT
CCCH zinc finger	0	DIRECT
BRK domain-like	0	DIRECT
Sec7 domain	0	DIRECT
JAB1/MPN domain	0	DIRECT
G protein-binding domain	0	DIRECT
Tricorn protease domain 2	0	DIRECT
BPTI-like	0	DIRECT
Nucleotidylyl transferase	0	DIRECT
Cullin repeat-like	0	DIRECT
Polo-box domain	0	DIRECT
Arginase/deacetylase	0	DIRECT
Metallo-dependent hydrolases	0	DIRECT
Glutathione synthetase ATP-binding domain-like	0	DIRECT
Tubulin C-terminal domain-like	0	DIRECT
CalX-like	0	DIRECT
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit	0	DIRECT
Composite domain of metallo-dependent hydrolases	0	DIRECT
Doublecortin (DC)	0	DIRECT
Nucleotide cyclase	0	DIRECT
Formin homology 2 domain (FH2 domain)	0	DIRECT
Ras GEF	0	DIRECT
SNARE fusion complex	0	DIRECT
Riboflavin synthase domain-like	0	DIRECT
Lipovitellin-phosvitin complex; beta-sheet shell regions	0	DIRECT
Mitochondrial carrier	0.2124	INHERITED FROM: intestine
ACT-like	0.3357	INHERITED FROM: artery || dorsal aorta || ventral wall of dorsal aorta
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains	0.3357	INHERITED FROM: artery || dorsal aorta || ventral wall of dorsal aorta
Cytochrome P450	0.3359	INHERITED FROM: hypophysis
Serine protease inhibitors	0.4223	INHERITED FROM: otolith organ || otolith
WD40 repeat-like	0.474	INHERITED FROM: retinal outer nuclear layer || photoreceptor outer segment layer
Immunoglobulin	0.474	INHERITED FROM: olfactory bulb glomerulus
SMAD/FHA domain	0.5188	INHERITED FROM: vein
PDZ domain-like	0.5191	INHERITED FROM: central canal
Glucocorticoid receptor-like (DNA-binding domain)	0.5543	INHERITED FROM: cardiac ventricle || VeLD || Kolmer-Agduhr neuron
lambda repressor-like DNA-binding domains	0.5788	INHERITED FROM: diencephalon
Cyclin-like	0.6427	INHERITED FROM: cranial nerve II
Cadherin-like	0.6696	INHERITED FROM: optic tectum || diencephalic white matter || cranial nerve II
Fibronectin type III	0.6844	INHERITED FROM: glomerular layer || synencephalon
Tropomyosin	0.7144	INHERITED FROM: sinus venosus
EGF/Laminin	0.7421	INHERITED FROM: blood vasculature
Cystine-knot cytokines	0.7434	INHERITED FROM: spermatogenic cyst
Hormone receptor domain	0.7918	INHERITED FROM: artery
Subtilisin-like	0.7934	INHERITED FROM: optic tectum
Protease propeptides/inhibitors	0.7934	INHERITED FROM: optic tectum
Carbonic anhydrase	0.7934	INHERITED FROM: swim bladder
Nuclear receptor ligand-binding domain	0.7934	INHERITED FROM: gonad || ovarian follicle stage IV || hypophysis
Multidrug efflux transporter AcrB transmembrane domain	0.7934	INHERITED FROM: retinal ganglion cell layer
NAD(P)-binding Rossmann-fold domains	0.7952	INHERITED FROM: retinal inner plexiform layer || retinal outer plexiform layer
beta-beta-alpha zinc fingers	0.8075	INHERITED FROM: ventral thalamus
Growth factor receptor domain	0.8984	INHERITED FROM: blood vasculature
Homeodomain-like	0.9072	INHERITED FROM: diencephalon || forebrain || preoptic area
DEATH domain	0.9108	INHERITED FROM: blood vasculature
HLH, helix-loop-helix DNA-binding domain	1	INHERITED FROM: Kolmer-Agduhr neuron

Family

Highlighted in gray are those with FDR_all>0.001

SCOP term	FDR (all)	Annotation (direct or inherited)
SRF-like	0	DIRECT
Elongation factors	0	DIRECT
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit	0	DIRECT
Platelet-derived growth factor-like	0	DIRECT
Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A	0	DIRECT
Actin/HSP70	0	DIRECT
Mammalian PLC	0	DIRECT
F-box domain	0	DIRECT
Formin homology 2 domain (FH2 domain)	0	DIRECT
Cdc48 domain 2-like	0	DIRECT
Ephrin receptor ligand binding domain	0	DIRECT
Hydantoinase (dihydropyrimidinase)	0	DIRECT
Sec7 domain	0	DIRECT
SNARE fusion complex	0	DIRECT
L domain	0	DIRECT
Aquaporin-like	0	DIRECT
Biotinyl/lipoyl-carrier proteins and domains	0	DIRECT
CalX-beta domain	0	DIRECT
Histone lysine methyltransferases	0	DIRECT
V set domains (antibody variable domain-like)	0	DIRECT
Adenylyl and guanylyl cyclase catalytic domain	0	DIRECT
Small Kunitz-type inhibitors & BPTI-like toxins	0	DIRECT
Lipovitellin-phosvitin complex; beta-sheet shell regions	0	DIRECT
Cap-Gly domain	0	DIRECT
C5 cytosine-specific DNA methylase, DCM	0	DIRECT
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta	0	DIRECT
Histone deacetylase, HDAC	0	DIRECT
Tubulin, GTPase domain	0	DIRECT
Noncollagenous (NC1) domain of collagen IV	0	DIRECT
Pyridoxal-dependent decarboxylase	0	DIRECT
CCCH zinc finger	0	DIRECT
Tubulin, C-terminal domain	0	DIRECT
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain	0	DIRECT
Phoshoinositide 3-kinase (PI3K), catalytic domain	0	DIRECT
LCCL domain	0	DIRECT
Connexin43	0	DIRECT
Phoshoinositide 3-kinase (PI3K) helical domain	0	DIRECT
Anticodon-binding domain of Class II aaRS	0	DIRECT
Reprolysin-like	0	DIRECT
Doublecortin (DC)	0	DIRECT
Extracellular domain of cell surface receptors	0	DIRECT
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	0	DIRECT
Heat shock protein 70kD (HSP70), peptide-binding domain	0	DIRECT
Nuclear receptor coactivator interlocking domain	0	DIRECT
Chromo domain	0	DIRECT
Hydantoinase (dihydropyrimidinase), catalytic domain	0	DIRECT
Glycerophosphoryl diester phosphodiesterase	0	DIRECT
Moesin tail domain	0	DIRECT
Erythroid transcription factor GATA-1	0	DIRECT
Tetramerization domain of potassium channels	0	DIRECT
Long-chain cytokines	0	DIRECT
Cell cycle transcription factor e2f-dp	0	DIRECT
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain	0	DIRECT
PP2C-like	0	DIRECT
Ras GEF	0	DIRECT
Pentraxin (pentaxin)	0	DIRECT
Cdc48 N-terminal domain-like	0	DIRECT
FHA domain	0	DIRECT
Rel/Dorsal transcription factors, DNA-binding domain	0	DIRECT
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	0	DIRECT
Class I aminoacyl-tRNA synthetases (RS), catalytic domain	0	DIRECT
Ovomucoid domain III-like	0	DIRECT
Single strand DNA-binding domain, SSB	0	DIRECT
Lipovitellin-phosvitin complex, superhelical domain	0	DIRECT
BRK domain-like	0	DIRECT
SWIRM domain	0	DIRECT
Motor proteins	0.03144	INHERITED FROM: renal corpuscle || pronephric podocyte || photoreceptor outer segment layer
Protein kinases, catalytic subunit	0.0833	INHERITED FROM: dorsal longitudinal anastomotic vessel
POU-specific domain	0.1818	INHERITED FROM: diencephalon || forebrain
Cytochrome P450	0.3003	INHERITED FROM: hypophysis
Phenylalanine metabolism regulatory domain	0.3014	INHERITED FROM: artery || dorsal aorta || ventral wall of dorsal aorta
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains	0.3014	INHERITED FROM: artery || dorsal aorta || ventral wall of dorsal aorta
Multidrug efflux transporter AcrB transmembrane domain	0.3014	INHERITED FROM: retinal ganglion cell layer
PDZ domain	0.3067	INHERITED FROM: central canal
Tetratricopeptide repeat (TPR)	0.3325	INHERITED FROM: retinal rod cell
T-box	0.3496	INHERITED FROM: atrioventricular canal || pronephros
LIM domain	0.3521	INHERITED FROM: cardiac ventricle
WD40-repeat	0.4099	INHERITED FROM: retinal cone cell || photoreceptor outer segment layer
Calcium ATPase, transmembrane domain M	0.4867	INHERITED FROM: atrium
Fibronectin type III	0.6341	INHERITED FROM: glomerular layer || synencephalon
Tropomyosin	0.6799	INHERITED FROM: sinus venosus
Cadherin	0.6859	INHERITED FROM: optic tectum || diencephalic white matter || cranial nerve II
I set domains	0.7049	INHERITED FROM: synencephalon
Nuclear receptor ligand-binding domain	0.7664	INHERITED FROM: gonad || ovarian follicle stage IV || hypophysis
Hormone receptor domain	0.769	INHERITED FROM: artery
Carbonic anhydrase	0.7738	INHERITED FROM: swim bladder
Nuclear receptor	0.7814	INHERITED FROM: gonad || ovarian follicle stage IV || hypophysis
Classic zinc finger, C2H2	0.8492	INHERITED FROM: ventral thalamus || thalamus
Transforming growth factor (TGF)-beta	0.8595	INHERITED FROM: spermatogenic cyst || pineal complex
Homeodomain	0.9435	INHERITED FROM: diencephalon || forebrain || dorsal telencephalon || preoptic area
HLH, helix-loop-helix DNA-binding domain	1	INHERITED FROM: Kolmer-Agduhr neuron

Supra-domain (Single|Duplex|Triple)

Supra-domain (Single)

Highlighted in gray are those with FDR>0.001

Supra-domain (Single)	FDR (all)	Annotation (direct or inherited)
Ras GEF	0	DIRECT
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	0	DIRECT
Class II aaRS ABD-related	0	DIRECT
BRK domain-like	0	DIRECT
Formin homology 2 domain (FH2 domain)	0	DIRECT
BRCT domain	0	DIRECT
Lipovitellin-phosvitin complex; beta-sheet shell regions	0	DIRECT
Tubulin C-terminal domain-like	0	DIRECT
Nuclear receptor coactivator interlocking domain	0	DIRECT
Ferredoxin reductase-like, C-terminal NADP-linked domain	0	DIRECT
SRF-like	0	DIRECT
Nucleotidylyl transferase	0	DIRECT
Tubulin nucleotide-binding domain-like	0	DIRECT
Metallo-dependent hydrolases	0	DIRECT
PLC-like phosphodiesterases	0	DIRECT
Cap-Gly domain	0	DIRECT
Tricorn protease domain 2	0	DIRECT
LCCL domain	0	DIRECT
Arginase/deacetylase	0	DIRECT
CCCH zinc finger	0	DIRECT
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	0	DIRECT
Heat shock protein 70kD (HSP70), peptide-binding domain	0	DIRECT
Aquaporin-like	0	DIRECT
Polo-box domain	0	DIRECT
Doublecortin (DC)	0	DIRECT
Single hybrid motif	0	DIRECT
Riboflavin synthase domain-like	0	DIRECT
Sec7 domain	0	DIRECT
Cullin repeat-like	0	DIRECT
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit	0	DIRECT
JAB1/MPN domain	0	DIRECT
Translation proteins	0	DIRECT
BPTI-like	0	DIRECT
Glutathione synthetase ATP-binding domain-like	0	DIRECT
Moesin tail domain	0	DIRECT
Nucleotide cyclase	0	DIRECT
Ypt/Rab-GAP domain of gyp1p	0	DIRECT
Composite domain of metallo-dependent hydrolases	0	DIRECT
SNARE fusion complex	0	DIRECT
ADC-like	0	DIRECT
PP2C-like	0	DIRECT
F-box domain	0	DIRECT
G protein-binding domain	0	DIRECT
Lipovitellin-phosvitin complex, superhelical domain	0	DIRECT
Translational machinery components	0	DIRECT
CalX-like	0	DIRECT
HIT-like	0	DIRECT
Cdc48 domain 2-like	0	DIRECT
Class II aaRS and biotin synthetases	0	DIRECT
Protein kinase-like (PK-like)	0.06282	INHERITED FROM: intersegmental vein
Mitochondrial carrier	0.1823	INHERITED FROM: intestine
ACT-like	0.3021	INHERITED FROM: ventral wall of dorsal aorta || artery || dorsal aorta
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains	0.3021	INHERITED FROM: ventral wall of dorsal aorta || artery || dorsal aorta
Cytochrome P450	0.3024	INHERITED FROM: hypophysis
Serine protease inhibitors	0.3875	INHERITED FROM: otolith || otolith organ
WD40 repeat-like	0.4401	INHERITED FROM: retinal photoreceptor layer || retinal outer nuclear layer || eye || photoreceptor outer segment layer
Immunoglobulin	0.4401	INHERITED FROM: synencephalon || glomerular layer || olfactory bulb glomerulus
SMAD/FHA domain	0.4869	INHERITED FROM: vein
PDZ domain-like	0.4873	INHERITED FROM: central canal
Glucocorticoid receptor-like (DNA-binding domain)	0.5233	INHERITED FROM: ovarian follicle stage IV || cardiac ventricle || Kolmer-Agduhr neuron || VeLD
lambda repressor-like DNA-binding domains	0.5482	INHERITED FROM: diencephalon
Cyclin-like	0.6149	INHERITED FROM: cranial nerve II
Cadherin-like	0.6423	INHERITED FROM: diencephalic white matter || optic tectum || cranial nerve II
Fibronectin type III	0.6583	INHERITED FROM: synencephalon || glomerular layer
Tropomyosin	0.6899	INHERITED FROM: sinus venosus
EGF/Laminin	0.72	INHERITED FROM: blood vasculature
Cystine-knot cytokines	0.7214	INHERITED FROM: spermatogenic cyst || cranial blood vessel || pineal complex
Hormone receptor domain	0.7745	INHERITED FROM: artery
Subtilisin-like	0.7762	INHERITED FROM: optic tectum
Protease propeptides/inhibitors	0.7762	INHERITED FROM: optic tectum
Multidrug efflux transporter AcrB transmembrane domain	0.7762	INHERITED FROM: retinal ganglion cell layer
Carbonic anhydrase	0.7762	INHERITED FROM: swim bladder
Nuclear receptor ligand-binding domain	0.7763	INHERITED FROM: hypophysis || ovarian follicle stage IV || gonad
NAD(P)-binding Rossmann-fold domains	0.7782	INHERITED FROM: retinal outer plexiform layer || retinal inner plexiform layer
Neurotransmitter-gated ion-channel transmembrane pore	0.781	INHERITED FROM: spinal cord
beta-beta-alpha zinc fingers	0.7916	INHERITED FROM: ventral thalamus
Growth factor receptor domain	0.8884	INHERITED FROM: blood vasculature
Homeodomain-like	0.8989	INHERITED FROM: preoptic area || dorsal telencephalon || forebrain || diencephalon
DEATH domain	0.9031	INHERITED FROM: blood vasculature
HLH, helix-loop-helix DNA-binding domain	1	INHERITED FROM: Kolmer-Agduhr neuron

Supra-domain (Duplex) in N- to C-terminal order

Highlighted in gray are those with FDR>0.001

Supra-domain (Duplex) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
54160,54160 54160 - Chromo domain-like 54160 - Chromo domain-like	0	DIRECT
89837,89837 89837 - Doublecortin (DC) 89837 - Doublecortin (DC)	0	DIRECT
57903,57903 57903 - FYVE/PHD zinc finger 57903 - FYVE/PHD zinc finger	0	DIRECT
141072,141072 141072 - CalX-like 141072 - CalX-like	0	DIRECT
52374,47323 52374 - Nucleotidylyl transferase 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	0	DIRECT
46785,46785 46785 - "Winged helix" DNA-binding domain 46785 - "Winged helix" DNA-binding domain	0	DIRECT
47473,51695 47473 - EF-hand 51695 - PLC-like phosphodiesterases	0	DIRECT
57362,57362 57362 - BPTI-like 57362 - BPTI-like	0	DIRECT
46966,47473 46966 - Spectrin repeat 47473 - EF-hand	0	DIRECT
56968,48431 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions 48431 - Lipovitellin-phosvitin complex, superhelical domain	0	DIRECT
57603,57603 57603 - FnI-like domain 57603 - FnI-like domain	0	DIRECT
52058,49265 52058 - L domain-like 49265 - Fibronectin type III	0	DIRECT
57196,63825 57196 - EGF/Laminin 63825 - YWTD domain	0	DIRECT
52490,55307 52490 - Tubulin nucleotide-binding domain-like 55307 - Tubulin C-terminal domain-like	0	DIRECT
48371,56112 48371 - ARM repeat 56112 - Protein kinase-like (PK-like)	0	DIRECT
53067,100920 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain	0	DIRECT
52058,57184 52058 - L domain-like 57184 - Growth factor receptor domain	0	DIRECT
50692,54585 50692 - ADC-like 54585 - Cdc48 domain 2-like	0	DIRECT
49417,81296 49417 - p53-like transcription factors 81296 - E set domains	0	DIRECT
57196,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases	0	DIRECT
54585,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases	0	DIRECT
52799,49562 52799 - (Phosphotyrosine protein) phosphatases II 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)	0	DIRECT
54160,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases	0	DIRECT
48097,56112 48097 - Regulator of G-protein signaling, RGS 56112 - Protein kinase-like (PK-like)	0	DIRECT
54791,54791 54791 - Eukaryotic type KH-domain (KH-domain type I) 54791 - Eukaryotic type KH-domain (KH-domain type I)	0	DIRECT
50978,50998 50978 - WD40 repeat-like 50998 - Quinoprotein alcohol dehydrogenase-like	0	DIRECT
48371,48371 48371 - ARM repeat 48371 - ARM repeat	0	DIRECT
52540,50447 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins	0	DIRECT
50447,50465 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	0	DIRECT
50729,56112 50729 - PH domain-like 56112 - Protein kinase-like (PK-like)	0	DIRECT
57184,52058 57184 - Growth factor receptor domain 52058 - L domain-like	0	DIRECT
55550,55550 55550 - SH2 domain 55550 - SH2 domain	0	DIRECT
56112,47769 56112 - Protein kinase-like (PK-like) 47769 - SAM/Pointed domain	0	DIRECT
51556,51338 51556 - Metallo-dependent hydrolases 51338 - Composite domain of metallo-dependent hydrolases	0	DIRECT
50729,47473 50729 - PH domain-like 47473 - EF-hand	0	DIRECT
49265,49899 49265 - Fibronectin type III 49899 - Concanavalin A-like lectins/glucanases	0	DIRECT
103575,81296 103575 - Plexin repeat 81296 - E set domains	0	DIRECT
48425,50729 48425 - Sec7 domain 50729 - PH domain-like	0	DIRECT
49562,48371 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat	0	DIRECT
63380,52343 63380 - Riboflavin synthase domain-like 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain	0	DIRECT
54001,143791 54001 - Cysteine proteinases 143791 - DUSP-like	0	DIRECT
57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain)	0.0574	INHERITED FROM: heart || cardiac ventricle || Kolmer-Agduhr neuron || VeLD
57184,57184 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain	0.1077	INHERITED FROM: blood vasculature || blood vessel
90257,90257 90257 - Myosin rod fragments 90257 - Myosin rod fragments	0.1823	INHERITED FROM: midbrain hindbrain boundary
55021,56534 55021 - ACT-like 56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains	0.3021	INHERITED FROM: ventral wall of dorsal aorta || artery || dorsal aorta
48726,49265 48726 - Immunoglobulin 49265 - Fibronectin type III	0.386	INHERITED FROM: brain nucleus || synencephalon
49562,48350 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48350 - GTPase activation domain, GAP	0.3875	INHERITED FROM: hindbrain
48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin	0.4922	INHERITED FROM: synencephalon
57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers	0.5688	INHERITED FROM: thalamus || ventral thalamus
54897,52743 54897 - Protease propeptides/inhibitors 52743 - Subtilisin-like	0.5773	INHERITED FROM: optic tectum
49265,49265 49265 - Fibronectin type III 49265 - Fibronectin type III	0.6584	INHERITED FROM: head kidney
48452,48452 48452 - TPR-like 48452 - TPR-like	0.6742	INHERITED FROM: pronephros
49313,49313 49313 - Cadherin-like 49313 - Cadherin-like	0.7443	INHERITED FROM: diencephalic white matter || optic tectum || cranial nerve II || retinal ganglion cell layer
50156,50156 50156 - PDZ domain-like 50156 - PDZ domain-like	0.781	INHERITED FROM: retinal outer nuclear layer || eye photoreceptor cell
57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin	0.8707	INHERITED FROM: blood vasculature

Supra-domain (Triple) in N- to C-terminal order

Highlighted in gray are those with FDR>0.001

Supra-domain (Triple) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
54585,52540,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases	0	DIRECT
57184,52058,57184 57184 - Growth factor receptor domain 52058 - L domain-like 57184 - Growth factor receptor domain	0	DIRECT
54160,54160,52540 54160 - Chromo domain-like 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases	0	DIRECT
57184,57184,57196 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain 57196 - EGF/Laminin	0	DIRECT
50729,47473,51695 50729 - PH domain-like 47473 - EF-hand 51695 - PLC-like phosphodiesterases	0	DIRECT
52058,57184,52058 52058 - L domain-like 57184 - Growth factor receptor domain 52058 - L domain-like	0	DIRECT
46966,46966,47473 46966 - Spectrin repeat 46966 - Spectrin repeat 47473 - EF-hand	0	DIRECT
57196,49899,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases	0	DIRECT
103575,81296,81296 103575 - Plexin repeat 81296 - E set domains 81296 - E set domains	0	DIRECT
49562,48371,56112 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat 56112 - Protein kinase-like (PK-like)	0	DIRECT
52058,49265,49265 52058 - L domain-like 49265 - Fibronectin type III 49265 - Fibronectin type III	0	DIRECT
90257,90257,90257 90257 - Myosin rod fragments 90257 - Myosin rod fragments 90257 - Myosin rod fragments	0	DIRECT
52540,50447,50465 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	0	DIRECT
57184,52058,49265 57184 - Growth factor receptor domain 52058 - L domain-like 49265 - Fibronectin type III	0	DIRECT
50692,54585,52540 50692 - ADC-like 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases	0	DIRECT
54160,52540,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases	0	DIRECT
53067,53067,100920 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain	0	DIRECT
57603,57603,57603 57603 - FnI-like domain 57603 - FnI-like domain 57603 - FnI-like domain	0	DIRECT
57716,57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain)	0.3024	INHERITED FROM: cardiac ventricle
48726,48726,49265 48726 - Immunoglobulin 48726 - Immunoglobulin 49265 - Fibronectin type III	0.5619	INHERITED FROM: brain nucleus || synencephalon
49313,49313,49313 49313 - Cadherin-like 49313 - Cadherin-like 49313 - Cadherin-like	0.617	INHERITED FROM: diencephalic white matter || optic tectum || cranial nerve II || retinal ganglion cell layer
48726,48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin 48726 - Immunoglobulin	0.631	INHERITED FROM: synencephalon