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CTD Chemicals (CC): Toxins, Biological 
(show info)
Biomedical Ontology
Like Gene Ontology (GO), biomedical ontology such as phenotype ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Biomedical ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI’s thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology Based on YP which is the major contributor to the ‘Ascomycete phenotype ontology’, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- UniProtKB KeyWords (KW) Ontology Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- CTD Diseases (CD) Ontology CD is MEDIC disease vocabulary that is modified by CTD from the "Diseases" [C] branch of Medical Subject Headings (MeSH), combined with genetic disorders from the Online Mendelian Inheritance in OMIM database.
- CTD Chemicals (CC) Ontology CC is chemical vocabulary that is adapted by CTD from the "Chemicals and Drugs" category and Supplementary Concept Records of Medical Subject Headings (MeSH, a hierarchical vocabulary used to index articles for MEDLINE/PubMed).
Jump to [ Top · Hierarchy · Annotations ]
Root: CC Hierarchy (CTD chemicals from Comparative Toxicogenomics Database)
Jump to [ Top · Hierarchy ]
Superfamily( show details)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| occludin/ELL-like | 0 | DIRECT |
| Serum albumin-like | 0 | DIRECT |
| BolA-like | 0 | DIRECT |
| Hypothetical protein YjiA, C-terminal domain | 0 | DIRECT |
| BAG domain | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| GINS helical bundle-like | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| Nitric oxide (NO) synthase oxygenase domain | 0 | DIRECT |
| PAH2 domain | 0 | DIRECT |
| I/LWEQ domain | 0 | DIRECT |
| LCCL domain | 0 | DIRECT |
| MAPEG domain-like | 0 | DIRECT |
| AXH domain | 0 | DIRECT |
| PUG domain-like | 0 | DIRECT |
| PHM/PNGase F | 0 | DIRECT |
| P-domain of calnexin/calreticulin | 0 | DIRECT |
| AhpD-like | 0 | DIRECT |
| LanC-like | 0 | DIRECT |
| MgtE membrane domain-like | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
| ClpS-like | 0 | DIRECT |
| Indolic compounds 2,3-dioxygenase-like | 0 | DIRECT |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| FAD-binding/transporter-associated domain-like | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| DNA clamp | 0 | DIRECT |
| FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
| ITPase-like | 0 | DIRECT |
| tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| Hairpin loop containing domain-like | 0 | DIRECT |
| ATP-dependent DNA ligase DNA-binding domain | 0 | DIRECT |
| Phosphofructokinase | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| N-terminal domain of cbl (N-cbl) | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Fibrinogen coiled-coil and central regions | 0 | DIRECT |
| p53 tetramerization domain | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| RGC domain-like | 0 | DIRECT |
| PriA/YqbF domain | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Flavoproteins | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| Transglutaminase, two C-terminal domains | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| FAS1 domain | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| FAD-linked oxidoreductase | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| TATA-box binding protein-like | 0 | DIRECT |
| DEATH domain | 0.0002094 | DIRECT |
| Tropomyosin | 0.00133 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins, Type A |
| Fibronectin type III | 0.003625 | INHERITED FROM: aflatoxin B2 || incobotulinumtoxinA || Botulinum Toxins, Type A |
| Protein kinase-like (PK-like) | 0.004524 | INHERITED FROM: Melitten || Sterigmatocystin || convulxin || 5-7-oxo-zeaenol || aflatoxin B2 || NKCT1 protein, Naja kaouthia || Ochratoxins || cholix toxin, Vibrio cholerae |
| Cadherin-like | 0.008324 | INHERITED FROM: Aflatoxins |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.01367 | INHERITED FROM: aflatoxin B2 |
| PH domain-like | 0.04272 | INHERITED FROM: Mycotoxins || aflatoxin B2 |
| Caspase-like | 0.04382 | INHERITED FROM: Venoms || Melitten || Enterotoxins || Endotoxins || Snake Venoms || Lipopolysaccharides || Trichothecenes || Ochratoxins || deoxynivalenol || cholix toxin, Vibrio cholerae || Bee Venoms || Bacterial Toxins || tcdA protein, Clostridium difficile |
| Bcl-2 inhibitors of programmed cell death | 0.05985 | INHERITED FROM: Trichothecenes || Ochratoxins || deoxynivalenol |
| Cytokine | 0.06324 | INHERITED FROM: Endotoxins || Lipopolysaccharides || Bee Venoms |
| SMAD/FHA domain | 0.09294 | INHERITED FROM: Cytochalasin D || Cytochalasins |
| Toll/Interleukin receptor TIR domain | 0.1392 | INHERITED FROM: lipopolysaccharide, E. coli O26-B6 || Endotoxins || Lipopolysaccharides || Bacterial Toxins |
| Voltage-gated potassium channels | 0.1416 | INHERITED FROM: Apamin || Tetrodotoxin || Arthropod Venoms |
| PDZ domain-like | 0.1775 | INHERITED FROM: aflatoxin B2 |
| Sema domain | 0.1886 | INHERITED FROM: Mycotoxins |
| Rhodanese/Cell cycle control phosphatase | 0.1901 | INHERITED FROM: Trichothecenes |
| PYP-like sensor domain (PAS domain) | 0.205 | INHERITED FROM: azaspiracid |
| EGF/Laminin | 0.207 | INHERITED FROM: aflatoxin B2 |
| Fibrinogen C-terminal domain-like | 0.2228 | INHERITED FROM: azaspiracid |
| Cytochrome P450 | 0.2653 | INHERITED FROM: cylindrospermopsin || Sterigmatocystin || HT-2 toxin || aflatoxin B1-DNA adduct || Sporidesmins || Amphibian Venoms || Trichothecenes || aflatoxin G1 || deoxynivalenol || Bufotenin |
| DBL homology domain (DH-domain) | 0.2807 | INHERITED FROM: aflatoxin B2 |
| ABC transporter transmembrane region | 0.2848 | INHERITED FROM: Zeranol || zearalenol |
| Cysteine-rich domain | 0.2969 | INHERITED FROM: aflatoxin B2 |
| Metallothionein | 0.3508 | INHERITED FROM: azaspiracid || Marine Toxins |
| Interleukin 8-like chemokines | 0.3706 | INHERITED FROM: Enterotoxins || lipopolysaccharide, E. coli O26-B6 || Virulence Factors || fumonisin B1 || Endotoxins || lipopolysaccharide, Helicobacter pylori || Lipopolysaccharides || Shiga Toxin 2 || Trichothecenes || Zearalenone || Fumonisins || Bacterial Toxins |
| P-loop containing nucleoside triphosphate hydrolases | 0.407 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.412 | INHERITED FROM: Zearalenone |
| TNF receptor-like | 0.416 | INHERITED FROM: Venoms || Melitten || Lipopolysaccharides || Bee Venoms |
| Nuclear receptor ligand-binding domain | 0.4272 | INHERITED FROM: Virulence Factors || Zeranol || Mycotoxins || Trichothecenes || Zearalenone |
| Class II aaRS and biotin synthetases | 0.4504 | INHERITED FROM: Lipopolysaccharides |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0.4705 | INHERITED FROM: Endotoxins || Ochratoxins |
| PGBD-like | 0.479 | INHERITED FROM: Endotoxins || Lipopolysaccharides || Bee Venoms || Arthropod Venoms |
| alpha/beta knot | 0.4964 | INHERITED FROM: cylindrospermopsin |
| Histone-fold | 0.4972 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins || Botulinum Toxins, Type A || Bacterial Toxins |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.5135 | INHERITED FROM: Venoms || Cnidarian Venoms || Endotoxins || Marine Toxins || palytoxin || Lipopolysaccharides |
| Riboflavin synthase domain-like | 0.5135 | INHERITED FROM: Venoms || Cnidarian Venoms || Endotoxins || Marine Toxins || palytoxin || Lipopolysaccharides |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.5189 | INHERITED FROM: Endotoxins |
| Somatomedin B domain | 0.5189 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins || Botulinum Toxins, Type A |
| Periplasmic binding protein-like I | 0.5348 | INHERITED FROM: conotoxin GV || Mollusk Venoms |
| TNF-like | 0.5371 | INHERITED FROM: Endotoxins || Lipopolysaccharides || brevetoxin 2 || Bacterial Toxins |
| E2F-DP heterodimerization region | 0.5695 | INHERITED FROM: Ochratoxins |
| STAT | 0.5695 | INHERITED FROM: Endotoxins || Lipopolysaccharides || Bacterial Toxins |
| Transcription factor STAT-4 N-domain | 0.5695 | INHERITED FROM: Endotoxins || Lipopolysaccharides || Bacterial Toxins |
| Cation efflux protein transmembrane domain-like | 0.5945 | INHERITED FROM: Ochratoxins |
| Complement control module/SCR domain | 0.5962 | INHERITED FROM: Aflatoxin B1 |
| p53-like transcription factors | 0.6079 | INHERITED FROM: Endotoxins || Lipopolysaccharides || deoxynivalenol || Bee Venoms || Cytochalasins |
| Hemopexin-like domain | 0.6196 | INHERITED FROM: Lipopolysaccharides || Bee Venoms || Arthropod Venoms |
| Troponin coil-coiled subunits | 0.6274 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins || Botulinum Toxins, Type A |
| Thioredoxin-like | 0.6638 | INHERITED FROM: Marine Toxins |
| TIMP-like | 0.6704 | INHERITED FROM: lipopolysaccharide, E. coli O26-B6 |
| HLH, helix-loop-helix DNA-binding domain | 0.6811 | INHERITED FROM: azaspiracid |
| 4Fe-4S ferredoxins | 0.6897 | INHERITED FROM: Endotoxins || Lipopolysaccharides |
| Second domain of FERM | 0.6915 | INHERITED FROM: aflatoxin B2 |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.7059 | INHERITED FROM: Zearalenone |
| Metalloproteases ("zincins"), catalytic domain | 0.7123 | INHERITED FROM: Bee Venoms || Arthropod Venoms |
| Leucine zipper domain | 0.7201 | INHERITED FROM: Virulence Factors || cylindrospermopsin || Trichothecenes || Ochratoxins || Citrinin |
| Bromodomain | 0.7282 | INHERITED FROM: deoxynivalenol |
| Cyclin-like | 0.7313 | INHERITED FROM: Ochratoxins || Citrinin |
| MFS general substrate transporter | 0.7412 | INHERITED FROM: Cytochalasin B |
| SH3-domain | 0.7965 | INHERITED FROM: aflatoxin B2 |
| Cystine-knot cytokines | 0.7993 | INHERITED FROM: Enterotoxins || Marine Toxins || Lipopolysaccharides || Zearalenone || Bacterial Toxins |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.8045 | INHERITED FROM: cylindrospermopsin |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.8214 | INHERITED FROM: Venoms || Muscimol || Mollusk Venoms |
| Nicotinic receptor ligand binding domain-like | 0.8214 | INHERITED FROM: Venoms || Muscimol || Mollusk Venoms |
| Periplasmic binding protein-like II | 0.8584 | INHERITED FROM: conotoxin GV || Mollusk Venoms |
| Arginase/deacetylase | 0.9055 | INHERITED FROM: Viper Venoms || Snake Venoms || Crotalid Venoms |
| Growth factor receptor domain | 0.9505 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins |
| post-AAA+ oligomerization domain-like | 0.9523 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins || Botulinum Toxins, Type A |
| S15/NS1 RNA-binding domain | 0.9523 | INHERITED FROM: Ochratoxins |
| 4-helical cytokines | 0.955 | INHERITED FROM: Enterotoxins || Virulence Factors || fumonisin B1 || lipopolysaccharide, E coli O55-B5 || Endotoxins || Marine Toxins || Lipopolysaccharides || brevetoxin 2 || Trichothecenes || Patulin || Fumonisins || enterotoxin F, Staphylococcal || deoxynivalenol || Bacterial Toxins || Cytochalasins |
| L30e-like | 0.9859 | INHERITED FROM: cylindrospermopsin |
| KRAB domain (Kruppel-associated box) | 1 | INHERITED FROM: Aflatoxin M1 |
| A DNA-binding domain in eukaryotic transcription factors | 1 | INHERITED FROM: Trichothecenes || deoxynivalenol |
| beta-beta-alpha zinc fingers | 1 | INHERITED FROM: Aflatoxin M1 |
| SCOP hierarchy in SUPERFAMILY | 1 | INHERITED FROM: Bacterial Toxins |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| occludin/ELL-like | 0 | Direct |
| Serum albumin-like | 0 | Direct |
| BolA-like | 0 | Direct |
| Hypothetical protein YjiA, C-terminal domain | 0 | Direct |
| BAG domain | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| GINS helical bundle-like | 0 | Direct |
| SIS domain | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| Nitric oxide (NO) synthase oxygenase domain | 0 | Direct |
| PAH2 domain | 0 | Direct |
| I/LWEQ domain | 0 | Direct |
| LCCL domain | 0 | Direct |
| MAPEG domain-like | 0 | Direct |
| AXH domain | 0 | Direct |
| PUG domain-like | 0 | Direct |
| PHM/PNGase F | 0 | Direct |
| P-domain of calnexin/calreticulin | 0 | Direct |
| AhpD-like | 0 | Direct |
| LanC-like | 0 | Direct |
| MgtE membrane domain-like | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
| ClpS-like | 0 | Direct |
| Indolic compounds 2,3-dioxygenase-like | 0 | Direct |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| FAD-binding/transporter-associated domain-like | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| DNA clamp | 0 | Direct |
| FAD-linked oxidases, C-terminal domain | 0 | Direct |
| ITPase-like | 0 | Direct |
| tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| Hairpin loop containing domain-like | 0 | Direct |
| ATP-dependent DNA ligase DNA-binding domain | 0 | Direct |
| Phosphofructokinase | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| N-terminal domain of cbl (N-cbl) | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Fibrinogen coiled-coil and central regions | 0 | Direct |
| p53 tetramerization domain | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| RGC domain-like | 0 | Direct |
| PriA/YqbF domain | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Flavoproteins | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| Transglutaminase, two C-terminal domains | 0 | Direct |
| Ribosomal protein S18 | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| FAS1 domain | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| FAD-linked oxidoreductase | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| TATA-box binding protein-like | 0 | Direct |
| DEATH domain | 0.0002094 | Direct |
| Tropomyosin | 0.00133 | Inherited |
| Fibronectin type III | 0.003625 | Inherited |
| Protein kinase-like (PK-like) | 0.004524 | Inherited |
| Cadherin-like | 0.008324 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.01367 | Inherited |
| PH domain-like | 0.04272 | Inherited |
| Caspase-like | 0.04382 | Inherited |
| Bcl-2 inhibitors of programmed cell death | 0.05985 | Inherited |
| Cytokine | 0.06324 | Inherited |
| SMAD/FHA domain | 0.09294 | Inherited |
| Toll/Interleukin receptor TIR domain | 0.1392 | Inherited |
| Voltage-gated potassium channels | 0.1416 | Inherited |
| PDZ domain-like | 0.1775 | Inherited |
| Sema domain | 0.1886 | Inherited |
| Rhodanese/Cell cycle control phosphatase | 0.1901 | Inherited |
| PYP-like sensor domain (PAS domain) | 0.205 | Inherited |
| EGF/Laminin | 0.207 | Inherited |
| Fibrinogen C-terminal domain-like | 0.2228 | Inherited |
| Cytochrome P450 | 0.2653 | Inherited |
| DBL homology domain (DH-domain) | 0.2807 | Inherited |
| ABC transporter transmembrane region | 0.2848 | Inherited |
| Cysteine-rich domain | 0.2969 | Inherited |
| Metallothionein | 0.3508 | Inherited |
| Interleukin 8-like chemokines | 0.3706 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.407 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.412 | Inherited |
| TNF receptor-like | 0.416 | Inherited |
| Nuclear receptor ligand-binding domain | 0.4272 | Inherited |
| Class II aaRS and biotin synthetases | 0.4504 | Inherited |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0.4705 | Inherited |
| PGBD-like | 0.479 | Inherited |
| alpha/beta knot | 0.4964 | Inherited |
| Histone-fold | 0.4972 | Inherited |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.5135 | Inherited |
| Riboflavin synthase domain-like | 0.5135 | Inherited |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.5189 | Inherited |
| Somatomedin B domain | 0.5189 | Inherited |
| Periplasmic binding protein-like I | 0.5348 | Inherited |
| TNF-like | 0.5371 | Inherited |
| E2F-DP heterodimerization region | 0.5695 | Inherited |
| STAT | 0.5695 | Inherited |
| Transcription factor STAT-4 N-domain | 0.5695 | Inherited |
| Cation efflux protein transmembrane domain-like | 0.5945 | Inherited |
| Complement control module/SCR domain | 0.5962 | Inherited |
| p53-like transcription factors | 0.6079 | Inherited |
| Hemopexin-like domain | 0.6196 | Inherited |
| Troponin coil-coiled subunits | 0.6274 | Inherited |
| Thioredoxin-like | 0.6638 | Inherited |
| TIMP-like | 0.6704 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.6811 | Inherited |
| 4Fe-4S ferredoxins | 0.6897 | Inherited |
| Second domain of FERM | 0.6915 | Inherited |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.7059 | Inherited |
| Metalloproteases ("zincins"), catalytic domain | 0.7123 | Inherited |
| Leucine zipper domain | 0.7201 | Inherited |
| Bromodomain | 0.7282 | Inherited |
| Cyclin-like | 0.7313 | Inherited |
| MFS general substrate transporter | 0.7412 | Inherited |
| SH3-domain | 0.7965 | Inherited |
| Cystine-knot cytokines | 0.7993 | Inherited |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.8045 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.8214 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.8214 | Inherited |
| Periplasmic binding protein-like II | 0.8584 | Inherited |
| Arginase/deacetylase | 0.9055 | Inherited |
| Growth factor receptor domain | 0.9505 | Inherited |
| post-AAA+ oligomerization domain-like | 0.9523 | Inherited |
| S15/NS1 RNA-binding domain | 0.9523 | Inherited |
| 4-helical cytokines | 0.955 | Inherited |
| L30e-like | 0.9859 | Inherited |
| KRAB domain (Kruppel-associated box) | 1 | Inherited |
| A DNA-binding domain in eukaryotic transcription factors | 1 | Inherited |
| beta-beta-alpha zinc fingers | 1 | Inherited |
| SCOP hierarchy in SUPERFAMILY | 1 | Inherited |
LINKTO: Domain2BO Download and Domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Family( show details)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| Sec63 N-terminal domain | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| Other IPT/TIG domains | 0 | DIRECT |
| C5 cytosine-specific DNA methylase, DCM | 0 | DIRECT |
| PreBEACH PH-like domain | 0 | DIRECT |
| p53 tetramerization domain | 0 | DIRECT |
| Proprotein convertase P-domain | 0 | DIRECT |
| BolA-like | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| AXH domain | 0 | DIRECT |
| NADPH-cytochrome p450 reductase FAD-binding domain-like | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | DIRECT |
| Phenylalanine metabolism regulatory domain | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase) | 0 | DIRECT |
| DNA ligase | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| Ribonuclease H | 0 | DIRECT |
| Methyl-CpG-binding domain, MBD | 0 | DIRECT |
| DEATH effector domain, DED | 0 | DIRECT |
| DNA gyrase/MutL, N-terminal domain | 0 | DIRECT |
| CUT domain | 0 | DIRECT |
| MHCK/EF2 kinase | 0 | DIRECT |
| tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
| MAPEG domain | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | DIRECT |
| Phosphofructokinase | 0 | DIRECT |
| alpha-catenin/vinculin | 0 | DIRECT |
| NagB-like | 0 | DIRECT |
| Arginase-like amidino hydrolases | 0 | DIRECT |
| PAS domain of steroid receptor coactivator 1A, NCo-A1 | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, catalytic C-terminal domain | 0 | DIRECT |
| Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | DIRECT |
| P-domain of calnexin/calreticulin | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | DIRECT |
| acyl-CoA oxidase C-terminal domains | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Troponin T | 0 | DIRECT |
| Fibrinogen coiled-coil and central regions | 0 | DIRECT |
| Selenoprotein W-related | 0 | DIRECT |
| PUG domain | 0 | DIRECT |
| Tetrahydrofolate dehydrogenase/cyclohydrolase | 0 | DIRECT |
| Crotonase-like | 0 | DIRECT |
| Alpha-adaptin ear subdomain-like | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | DIRECT |
| Prohormone convertase 1 pro-domain | 0 | DIRECT |
| Trunk domain of Sec23/24 | 0 | DIRECT |
| Vertebrate phospholipase A2 | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| ATP-dependent DNA ligase catalytic domain | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| Transglutaminase N-terminal domain | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| p53 DNA-binding domain-like | 0 | DIRECT |
| Synapsin domain | 0 | DIRECT |
| NIPSNAP | 0 | DIRECT |
| Occludin/ELL domain | 0 | DIRECT |
| Clathrin heavy-chain linker domain | 0 | DIRECT |
| FAS1 domain | 0 | DIRECT |
| NagD-like | 0 | DIRECT |
| Adenylyltransferase | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| LanC-like | 0 | DIRECT |
| NADPH-cytochrome p450 reductase-like | 0 | DIRECT |
| LCCL domain | 0 | DIRECT |
| Retinoblastoma tumor suppressor domains | 0 | DIRECT |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| Serum albumin-like | 0 | DIRECT |
| Transglutaminase, two C-terminal domains | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| Kringle modules | 0 | DIRECT |
| 5' to 3' exonuclease catalytic domain | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, N-terminal domain | 0 | DIRECT |
| Nitric oxide (NO) synthase oxygenase domain | 0 | DIRECT |
| Hexokinase | 0 | DIRECT |
| Synapsin C-terminal domain | 0 | DIRECT |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| RPR domain (SMART 00582 ) | 0 | DIRECT |
| Calnexin/calreticulin | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| GHMP Kinase, N-terminal domain | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| N-terminal domain of cbl (N-cbl) | 0 | DIRECT |
| L-aspartase/fumarase | 0 | DIRECT |
| Variant SAM domain | 0 | DIRECT |
| acyl-CoA oxidase N-terminal domains | 0 | DIRECT |
| Sec63 C-terminal domain-like | 0 | DIRECT |
| I/LWEQ domain | 0 | DIRECT |
| Transglutaminase core | 0 | DIRECT |
| Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
| Ferredoxin domains from multidomain proteins | 0 | DIRECT |
| Tissue inhibitor of metalloproteinases, TIMP | 0 | DIRECT |
| SH3BGR (SH3-binding, glutamic acid-rich protein-like) | 0 | DIRECT |
| Clathrin adaptor appendage, alpha and beta chain-specific domain | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| Malic enzyme N-domain | 0 | DIRECT |
| TATA-box binding protein (TBP), C-terminal domain | 0 | DIRECT |
| Interleukin-1 (IL-1) | 0 | DIRECT |
| SMAD domain | 0 | DIRECT |
| RNA methyltransferase FtsJ | 0 | DIRECT |
| Cytochrome p450 reductase N-terminal domain-like | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme postcatalytic domain | 0 | DIRECT |
| Cripto EGF-like domain-like | 0 | DIRECT |
| BAG domain | 0 | DIRECT |
| DNA gyrase/MutL, second domain | 0 | DIRECT |
| CAD domain | 0 | DIRECT |
| RGC domain | 0 | DIRECT |
| Hypothetical protein YjiA, C-terminal domain | 0 | DIRECT |
| HCDH C-domain-like | 0 | DIRECT |
| Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
| GRAM domain | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| PAH2 domain | 0 | DIRECT |
| Laminin G-like module | 0.00007527 | DIRECT |
| DEATH domain, DD | 0.0004022 | DIRECT |
| Tropomyosin | 0.00122 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins, Type A |
| Caspase recruitment domain, CARD | 0.00122 | INHERITED FROM: Lipopolysaccharides || deoxynivalenol |
| Fibronectin type III | 0.002406 | INHERITED FROM: aflatoxin B2 |
| Motor proteins | 0.002683 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins || Botulinum Toxins, Type A |
| Cadherin | 0.007274 | INHERITED FROM: Aflatoxins |
| Protein kinases, catalytic subunit | 0.007649 | INHERITED FROM: convulxin || 5-7-oxo-zeaenol || aflatoxin B2 || NKCT1 protein, Naja kaouthia || Ochratoxins || Citrinin || cholix toxin, Vibrio cholerae |
| Glutathione peroxidase-like | 0.01544 | INHERITED FROM: Bacterial Toxins |
| Bcl-2 inhibitors of programmed cell death | 0.05625 | INHERITED FROM: Trichothecenes || Ochratoxins || deoxynivalenol |
| I set domains | 0.07155 | INHERITED FROM: aflatoxin B2 |
| Caspase catalytic domain | 0.07615 | INHERITED FROM: Venoms || Melitten || Enterotoxins || Endotoxins || Snake Venoms || Lipopolysaccharides || Trichothecenes || Ochratoxins || deoxynivalenol || cholix toxin, Vibrio cholerae || Bee Venoms || Bacterial Toxins || tcdA protein, Clostridium difficile |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0.0832 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins || Botulinum Toxins, Type A |
| ABC transporter transmembrane region | 0.1057 | INHERITED FROM: Zeranol || zearalenol |
| Toll/Interleukin receptor TIR domain | 0.1327 | INHERITED FROM: lipopolysaccharide, E. coli O26-B6 || Endotoxins || Lipopolysaccharides || Bacterial Toxins |
| Sema domain | 0.1629 | INHERITED FROM: Mycotoxins |
| TNF receptor-like | 0.1659 | INHERITED FROM: Venoms || Melitten || Lipopolysaccharides || Bee Venoms |
| Fibrinogen C-terminal domain-like | 0.1944 | INHERITED FROM: azaspiracid |
| Dual specificity phosphatase-like | 0.2326 | INHERITED FROM: cylindrospermopsin |
| Cytochrome P450 | 0.245 | INHERITED FROM: cylindrospermopsin || Sterigmatocystin || HT-2 toxin || aflatoxin B1-DNA adduct || Sporidesmins || Amphibian Venoms || Trichothecenes || aflatoxin G1 || deoxynivalenol || Bufotenin |
| DBL homology domain (DH-domain) | 0.245 | INHERITED FROM: aflatoxin B2 |
| Cyclin | 0.2742 | INHERITED FROM: Ochratoxins || Citrinin |
| Short-chain cytokines | 0.2857 | INHERITED FROM: Cytochalasin B || Endotoxins || Marine Toxins || Lipopolysaccharides || brevetoxin 2 || Trichothecenes || Zearalenone || deoxynivalenol || Bacterial Toxins || Cytochalasins |
| Metallothionein | 0.3173 | INHERITED FROM: azaspiracid || Marine Toxins |
| Interleukin 8-like chemokines | 0.3309 | INHERITED FROM: Enterotoxins || lipopolysaccharide, E. coli O26-B6 || Virulence Factors || fumonisin B1 || Endotoxins || lipopolysaccharide, Helicobacter pylori || Lipopolysaccharides || Shiga Toxin 2 || Trichothecenes || Zearalenone || Fumonisins || Bacterial Toxins |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0.3309 | INHERITED FROM: aflatoxin B2 |
| Voltage-gated potassium channels | 0.3516 | INHERITED FROM: Venoms || Apamin || Arthropod Venoms |
| Nuclear receptor ligand-binding domain | 0.384 | INHERITED FROM: Virulence Factors || Zeranol || Mycotoxins || Trichothecenes || Zearalenone || 3-acetyldeoxynivalenol |
| Rel/Dorsal transcription factors, DNA-binding domain | 0.3911 | INHERITED FROM: lipopolysaccharide, E. coli O26-B6 || Endotoxins || Lipopolysaccharides || Trichothecenes || deoxynivalenol |
| PLC-like (P variant) | 0.3951 | INHERITED FROM: aflatoxin B2 |
| Nuclear receptor | 0.4253 | INHERITED FROM: Virulence Factors || Zeranol || Mycotoxins || Trichothecenes || Zearalenone || 3-acetyldeoxynivalenol |
| Glutathione S-transferase (GST), C-terminal domain | 0.4303 | INHERITED FROM: Marine Toxins |
| Interferon regulatory factor | 0.4336 | INHERITED FROM: Endotoxins || Lipopolysaccharides |
| Cell cycle transcription factor e2f-dp | 0.4336 | INHERITED FROM: Ochratoxins |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0.4394 | INHERITED FROM: Lipopolysaccharides || Bacterial Toxins |
| MMP N-terminal domain | 0.4394 | INHERITED FROM: Endotoxins || Lipopolysaccharides || Bee Venoms || Arthropod Venoms |
| UDPGT-like | 0.4743 | INHERITED FROM: cylindrospermopsin || Zearalenone |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0.4812 | INHERITED FROM: Ochratoxins |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0.4812 | INHERITED FROM: Ochratoxins |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.4812 | INHERITED FROM: Endotoxins |
| Somatomedin B domain | 0.4812 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins || Botulinum Toxins, Type A |
| LIM domain | 0.4925 | INHERITED FROM: Aflatoxin B1 |
| Nucleosome core histones | 0.5056 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins || Botulinum Toxins, Type A || Bacterial Toxins |
| STAT | 0.5318 | INHERITED FROM: Endotoxins || Lipopolysaccharides || Bacterial Toxins |
| Transcription factor STAT-4 N-domain | 0.5318 | INHERITED FROM: Endotoxins || Lipopolysaccharides || Bacterial Toxins |
| STAT DNA-binding domain | 0.5318 | INHERITED FROM: Endotoxins || Lipopolysaccharides || Bacterial Toxins |
| TNF-like | 0.5378 | INHERITED FROM: Endotoxins || Lipopolysaccharides || brevetoxin 2 || Bacterial Toxins |
| TBP-associated factors, TAFs | 0.5454 | INHERITED FROM: Aflatoxin M1 |
| Complement control module/SCR domain | 0.5485 | INHERITED FROM: Aflatoxin B1 |
| Pleckstrin-homology domain (PH domain) | 0.5592 | INHERITED FROM: aflatoxin B2 |
| ABC transporter ATPase domain-like | 0.5691 | INHERITED FROM: Zeranol || zearalenol |
| Hemopexin-like domain | 0.5774 | INHERITED FROM: Lipopolysaccharides || Bee Venoms || Arthropod Venoms |
| Interleukin 17F, IL-17F | 0.5898 | INHERITED FROM: Endotoxins || Lipopolysaccharides |
| HLH, helix-loop-helix DNA-binding domain | 0.6311 | INHERITED FROM: azaspiracid |
| TRASH domain | 0.6524 | INHERITED FROM: Aflatoxin M1 |
| E2F dimerization segment | 0.6524 | INHERITED FROM: Ochratoxins |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0.6524 | INHERITED FROM: incobotulinumtoxinA || Botulinum Toxins || Botulinum Toxins, Type A |
| Cation efflux protein transmembrane domain-like | 0.6619 | INHERITED FROM: Ochratoxins |
| Leucine zipper domain | 0.6749 | INHERITED FROM: Virulence Factors || cylindrospermopsin || Trichothecenes || Ochratoxins || Citrinin |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.6764 | INHERITED FROM: Endotoxins || Lipopolysaccharides |
| Phosphate binding protein-like | 0.7119 | INHERITED FROM: conotoxin GV || Mollusk Venoms |
| Bromodomain | 0.7234 | INHERITED FROM: deoxynivalenol |
| a tRNA synthase domain | 0.7234 | INHERITED FROM: Ochratoxins |
| SH3-domain | 0.7458 | INHERITED FROM: aflatoxin B2 |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.7844 | INHERITED FROM: Venoms || Muscimol || Mollusk Venoms |
| Extended AAA-ATPase domain | 0.7844 | INHERITED FROM: incobotulinumtoxinA |
| Matrix metalloproteases, catalytic domain | 0.7988 | INHERITED FROM: Endotoxins || Lipopolysaccharides || Bee Venoms || Arthropod Venoms |
| C2 set domains | 0.801 | INHERITED FROM: lipopolysaccharide, E coli O55-B5 |
| Nicotinic receptor ligand binding domain-like | 0.8071 | INHERITED FROM: Venoms || Muscimol || Mollusk Venoms |
| Transforming growth factor (TGF)-beta | 0.8147 | INHERITED FROM: Marine Toxins || Lipopolysaccharides || brevetoxin 2 || Bacterial Toxins |
| NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0.8796 | INHERITED FROM: lipopolysaccharide, E. coli O26-B6 || Endotoxins || Lipopolysaccharides || Trichothecenes || deoxynivalenol |
| Histone deacetylase, HDAC | 0.9663 | INHERITED FROM: Venoms || Viper Venoms || Snake Venoms || Crotalid Venoms |
| Long-chain cytokines | 0.9674 | INHERITED FROM: Virulence Factors, Bordetella || Virulence Factors || Endotoxins || Lipopolysaccharides || Trichothecenes || deoxynivalenol |
| A DNA-binding domain in eukaryotic transcription factors | 0.9901 | INHERITED FROM: Trichothecenes || deoxynivalenol |
| G proteins | 1 | INHERITED FROM: exoenzyme C3, Clostridium botulinum || 15-acetyldeoxynivalenol |
| KRAB domain (Kruppel-associated box) | 1 | INHERITED FROM: Aflatoxin M1 |
| Classic zinc finger, C2H2 | 1 | INHERITED FROM: Aflatoxin M1 |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| Sec63 N-terminal domain | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| Other IPT/TIG domains | 0 | Direct |
| C5 cytosine-specific DNA methylase, DCM | 0 | Direct |
| PreBEACH PH-like domain | 0 | Direct |
| p53 tetramerization domain | 0 | Direct |
| Proprotein convertase P-domain | 0 | Direct |
| BolA-like | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| AXH domain | 0 | Direct |
| NADPH-cytochrome p450 reductase FAD-binding domain-like | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | Direct |
| Phenylalanine metabolism regulatory domain | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| Hydantoinase (dihydropyrimidinase) | 0 | Direct |
| DNA ligase | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| Ribonuclease H | 0 | Direct |
| Methyl-CpG-binding domain, MBD | 0 | Direct |
| DEATH effector domain, DED | 0 | Direct |
| DNA gyrase/MutL, N-terminal domain | 0 | Direct |
| CUT domain | 0 | Direct |
| MHCK/EF2 kinase | 0 | Direct |
| tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
| MAPEG domain | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | Direct |
| Phosphofructokinase | 0 | Direct |
| alpha-catenin/vinculin | 0 | Direct |
| NagB-like | 0 | Direct |
| Arginase-like amidino hydrolases | 0 | Direct |
| PAS domain of steroid receptor coactivator 1A, NCo-A1 | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Peptidylarginine deiminase Pad4, catalytic C-terminal domain | 0 | Direct |
| Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | Direct |
| P-domain of calnexin/calreticulin | 0 | Direct |
| Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | Direct |
| acyl-CoA oxidase C-terminal domains | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Troponin T | 0 | Direct |
| Fibrinogen coiled-coil and central regions | 0 | Direct |
| Selenoprotein W-related | 0 | Direct |
| PUG domain | 0 | Direct |
| Tetrahydrofolate dehydrogenase/cyclohydrolase | 0 | Direct |
| Crotonase-like | 0 | Direct |
| Alpha-adaptin ear subdomain-like | 0 | Direct |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | Direct |
| Prohormone convertase 1 pro-domain | 0 | Direct |
| Trunk domain of Sec23/24 | 0 | Direct |
| Vertebrate phospholipase A2 | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| ATP-dependent DNA ligase catalytic domain | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| Transglutaminase N-terminal domain | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| p53 DNA-binding domain-like | 0 | Direct |
| Synapsin domain | 0 | Direct |
| NIPSNAP | 0 | Direct |
| Occludin/ELL domain | 0 | Direct |
| Clathrin heavy-chain linker domain | 0 | Direct |
| FAS1 domain | 0 | Direct |
| NagD-like | 0 | Direct |
| Adenylyltransferase | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| LanC-like | 0 | Direct |
| NADPH-cytochrome p450 reductase-like | 0 | Direct |
| LCCL domain | 0 | Direct |
| Retinoblastoma tumor suppressor domains | 0 | Direct |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| Serum albumin-like | 0 | Direct |
| Transglutaminase, two C-terminal domains | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| Kringle modules | 0 | Direct |
| 5' to 3' exonuclease catalytic domain | 0 | Direct |
| Peptidylarginine deiminase Pad4, N-terminal domain | 0 | Direct |
| Nitric oxide (NO) synthase oxygenase domain | 0 | Direct |
| Hexokinase | 0 | Direct |
| Synapsin C-terminal domain | 0 | Direct |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| RPR domain (SMART 00582 ) | 0 | Direct |
| Calnexin/calreticulin | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| GHMP Kinase, N-terminal domain | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| N-terminal domain of cbl (N-cbl) | 0 | Direct |
| L-aspartase/fumarase | 0 | Direct |
| Variant SAM domain | 0 | Direct |
| acyl-CoA oxidase N-terminal domains | 0 | Direct |
| Sec63 C-terminal domain-like | 0 | Direct |
| I/LWEQ domain | 0 | Direct |
| Transglutaminase core | 0 | Direct |
| Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
| Ferredoxin domains from multidomain proteins | 0 | Direct |
| Tissue inhibitor of metalloproteinases, TIMP | 0 | Direct |
| SH3BGR (SH3-binding, glutamic acid-rich protein-like) | 0 | Direct |
| Clathrin adaptor appendage, alpha and beta chain-specific domain | 0 | Direct |
| Ribosomal protein S18 | 0 | Direct |
| Malic enzyme N-domain | 0 | Direct |
| TATA-box binding protein (TBP), C-terminal domain | 0 | Direct |
| Interleukin-1 (IL-1) | 0 | Direct |
| SMAD domain | 0 | Direct |
| RNA methyltransferase FtsJ | 0 | Direct |
| Cytochrome p450 reductase N-terminal domain-like | 0 | Direct |
| DNA ligase/mRNA capping enzyme postcatalytic domain | 0 | Direct |
| Cripto EGF-like domain-like | 0 | Direct |
| BAG domain | 0 | Direct |
| DNA gyrase/MutL, second domain | 0 | Direct |
| CAD domain | 0 | Direct |
| RGC domain | 0 | Direct |
| Hypothetical protein YjiA, C-terminal domain | 0 | Direct |
| HCDH C-domain-like | 0 | Direct |
| Cell cycle control phosphatase, catalytic domain | 0 | Direct |
| GRAM domain | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| PAH2 domain | 0 | Direct |
| Laminin G-like module | 0.00007527 | Direct |
| DEATH domain, DD | 0.0004022 | Direct |
| Tropomyosin | 0.00122 | Inherited |
| Caspase recruitment domain, CARD | 0.00122 | Inherited |
| Fibronectin type III | 0.002406 | Inherited |
| Motor proteins | 0.002683 | Inherited |
| Cadherin | 0.007274 | Inherited |
| Protein kinases, catalytic subunit | 0.007649 | Inherited |
| Glutathione peroxidase-like | 0.01544 | Inherited |
| Bcl-2 inhibitors of programmed cell death | 0.05625 | Inherited |
| I set domains | 0.07155 | Inherited |
| Caspase catalytic domain | 0.07615 | Inherited |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0.0832 | Inherited |
| ABC transporter transmembrane region | 0.1057 | Inherited |
| Toll/Interleukin receptor TIR domain | 0.1327 | Inherited |
| Sema domain | 0.1629 | Inherited |
| TNF receptor-like | 0.1659 | Inherited |
| Fibrinogen C-terminal domain-like | 0.1944 | Inherited |
| Dual specificity phosphatase-like | 0.2326 | Inherited |
| Cytochrome P450 | 0.245 | Inherited |
| DBL homology domain (DH-domain) | 0.245 | Inherited |
| Cyclin | 0.2742 | Inherited |
| Short-chain cytokines | 0.2857 | Inherited |
| Metallothionein | 0.3173 | Inherited |
| Interleukin 8-like chemokines | 0.3309 | Inherited |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0.3309 | Inherited |
| Voltage-gated potassium channels | 0.3516 | Inherited |
| Nuclear receptor ligand-binding domain | 0.384 | Inherited |
| Rel/Dorsal transcription factors, DNA-binding domain | 0.3911 | Inherited |
| PLC-like (P variant) | 0.3951 | Inherited |
| Nuclear receptor | 0.4253 | Inherited |
| Glutathione S-transferase (GST), C-terminal domain | 0.4303 | Inherited |
| Interferon regulatory factor | 0.4336 | Inherited |
| Cell cycle transcription factor e2f-dp | 0.4336 | Inherited |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0.4394 | Inherited |
| MMP N-terminal domain | 0.4394 | Inherited |
| UDPGT-like | 0.4743 | Inherited |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0.4812 | Inherited |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0.4812 | Inherited |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.4812 | Inherited |
| Somatomedin B domain | 0.4812 | Inherited |
| LIM domain | 0.4925 | Inherited |
| Nucleosome core histones | 0.5056 | Inherited |
| STAT | 0.5318 | Inherited |
| Transcription factor STAT-4 N-domain | 0.5318 | Inherited |
| STAT DNA-binding domain | 0.5318 | Inherited |
| TNF-like | 0.5378 | Inherited |
| TBP-associated factors, TAFs | 0.5454 | Inherited |
| Complement control module/SCR domain | 0.5485 | Inherited |
| Pleckstrin-homology domain (PH domain) | 0.5592 | Inherited |
| ABC transporter ATPase domain-like | 0.5691 | Inherited |
| Hemopexin-like domain | 0.5774 | Inherited |
| Interleukin 17F, IL-17F | 0.5898 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.6311 | Inherited |
| TRASH domain | 0.6524 | Inherited |
| E2F dimerization segment | 0.6524 | Inherited |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0.6524 | Inherited |
| Cation efflux protein transmembrane domain-like | 0.6619 | Inherited |
| Leucine zipper domain | 0.6749 | Inherited |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.6764 | Inherited |
| Phosphate binding protein-like | 0.7119 | Inherited |
| Bromodomain | 0.7234 | Inherited |
| a tRNA synthase domain | 0.7234 | Inherited |
| SH3-domain | 0.7458 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.7844 | Inherited |
| Extended AAA-ATPase domain | 0.7844 | Inherited |
| Matrix metalloproteases, catalytic domain | 0.7988 | Inherited |
| C2 set domains | 0.801 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.8071 | Inherited |
| Transforming growth factor (TGF)-beta | 0.8147 | Inherited |
| NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0.8796 | Inherited |
| Histone deacetylase, HDAC | 0.9663 | Inherited |
| Long-chain cytokines | 0.9674 | Inherited |
| A DNA-binding domain in eukaryotic transcription factors | 0.9901 | Inherited |
| G proteins | 1 | Inherited |
| KRAB domain (Kruppel-associated box) | 1 | Inherited |
| Classic zinc finger, C2H2 | 1 | Inherited |
LINKTO: Domain2BO Download and Domain2BO Algorithm
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Supra-domain (Single)( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
| Flavoproteins | 0 | DIRECT |
| ATP-dependent DNA ligase DNA-binding domain | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| Fibrinogen coiled-coil and central regions | 0 | DIRECT |
| BAG domain | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| PHM/PNGase F | 0 | DIRECT |
| occludin/ELL-like | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| ITPase-like | 0 | DIRECT |
| P-domain of calnexin/calreticulin | 0 | DIRECT |
| p53 tetramerization domain | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | DIRECT |
| Nitric oxide (NO) synthase oxygenase domain | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| LanC-like | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| PriA/YqbF domain | 0 | DIRECT |
| MAPEG domain-like | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| N-terminal domain of cbl (N-cbl) | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Hypothetical protein YjiA, C-terminal domain | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| LCCL domain | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | DIRECT |
| Serum albumin-like | 0 | DIRECT |
| RGC domain-like | 0 | DIRECT |
| PUG domain-like | 0 | DIRECT |
| PAH2 domain | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| MgtE membrane domain-like | 0 | DIRECT |
| DNA clamp | 0 | DIRECT |
| AXH domain | 0 | DIRECT |
| Transglutaminase, two C-terminal domains | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
| Indolic compounds 2,3-dioxygenase-like | 0 | DIRECT |
| FAD-binding/transporter-associated domain-like | 0 | DIRECT |
| FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| ClpS-like | 0 | DIRECT |
| FAD-linked oxidoreductase | 0 | DIRECT |
| AhpD-like | 0 | DIRECT |
| Phosphofructokinase | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| TATA-box binding protein-like | 0 | DIRECT |
| Hairpin loop containing domain-like | 0 | DIRECT |
| I/LWEQ domain | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
| FAS1 domain | 0 | DIRECT |
| GINS helical bundle-like | 0 | DIRECT |
| BolA-like | 0 | DIRECT |
| DEATH domain | 0.0001159 | DIRECT |
| Tropomyosin | 0.0008061 | DIRECT |
| Fibronectin type III | 0.002309 | INHERITED FROM: Botulinum Toxins, Type A || aflatoxin B2 || incobotulinumtoxinA |
| Protein kinase-like (PK-like) | 0.002917 | INHERITED FROM: convulxin || Citrinin || 5-7-oxo-zeaenol || aflatoxin B2 || Ochratoxins || Melitten || NKCT1 protein, Naja kaouthia || Sterigmatocystin || cholix toxin, Vibrio cholerae |
| Cadherin-like | 0.005553 | INHERITED FROM: Aflatoxins |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.009378 | INHERITED FROM: aflatoxin B2 |
| PH domain-like | 0.03133 | INHERITED FROM: aflatoxin B2 || Mycotoxins |
| Caspase-like | 0.03219 | INHERITED FROM: deoxynivalenol || Bacterial Toxins || Endotoxins || Trichothecenes || Enterotoxins || Ochratoxins || Zearalenone || Snake Venoms || Melitten || Venoms || tcdA protein, Clostridium difficile || Lipopolysaccharides || cholix toxin, Vibrio cholerae || Bee Venoms |
| Bcl-2 inhibitors of programmed cell death | 0.0447 | INHERITED FROM: deoxynivalenol || Trichothecenes || Ochratoxins || Lipopolysaccharides |
| Cytokine | 0.04736 | INHERITED FROM: Endotoxins || Lipopolysaccharides || Bee Venoms |
| SMAD/FHA domain | 0.07113 | INHERITED FROM: Cytochalasin D || Cytochalasins |
| GTPase activation domain, GAP | 0.09621 | INHERITED FROM: aflatoxin B2 |
| Toll/Interleukin receptor TIR domain | 0.1091 | INHERITED FROM: Bacterial Toxins || Endotoxins || lipopolysaccharide, E. coli O26-B6 || Lipopolysaccharides |
| Voltage-gated potassium channels | 0.1111 | INHERITED FROM: Arthropod Venoms || Tetrodotoxin || Venoms || Apamin |
| Polo-box domain | 0.141 | INHERITED FROM: Bacterial Toxins |
| PDZ domain-like | 0.1412 | INHERITED FROM: aflatoxin B2 |
| Sema domain | 0.1507 | INHERITED FROM: Mycotoxins |
| Rhodanese/Cell cycle control phosphatase | 0.1521 | INHERITED FROM: Trichothecenes |
| PYP-like sensor domain (PAS domain) | 0.1649 | INHERITED FROM: azaspiracid |
| EGF/Laminin | 0.1667 | INHERITED FROM: aflatoxin B2 |
| Fibrinogen C-terminal domain-like | 0.1803 | INHERITED FROM: azaspiracid |
| Cytochrome P450 | 0.2175 | INHERITED FROM: Bufotenin || deoxynivalenol || Bacterial Toxins || aflatoxin G1 || Aflatoxin B1 || Trichothecenes || Sporidesmins || aflatoxin B1-DNA adduct || Sterigmatocystin || HT-2 toxin || Amphibian Venoms || cylindrospermopsin |
| DBL homology domain (DH-domain) | 0.2309 | INHERITED FROM: aflatoxin B2 |
| ABC transporter transmembrane region | 0.2346 | INHERITED FROM: Zeranol || zearalenol |
| Cysteine-rich domain | 0.2452 | INHERITED FROM: aflatoxin B2 |
| Metallothionein | 0.2943 | INHERITED FROM: Marine Toxins || azaspiracid |
| Interleukin 8-like chemokines | 0.3122 | INHERITED FROM: Virulence Factors || Bacterial Toxins || Endotoxins || lipopolysaccharide, Helicobacter pylori || Virulence Factors, Bordetella || Trichothecenes || Enterotoxins || lipopolysaccharide, E. coli O26-B6 || Zearalenone || fumonisin B1 || Shiga Toxin 2 || Fumonisins || Lipopolysaccharides |
| WW domain | 0.3316 | INHERITED FROM: aflatoxin B2 |
| P-loop containing nucleoside triphosphate hydrolases | 0.3454 | INHERITED FROM: Botulinum Toxins || incobotulinumtoxinA |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.35 | INHERITED FROM: Zearalenone || 3-acetyldeoxynivalenol || Zeranol |
| TNF receptor-like | 0.3538 | INHERITED FROM: lipopolysaccharide, E. coli O26-B6 || Melitten || Venoms || Lipopolysaccharides || Bee Venoms |
| Nuclear receptor ligand-binding domain | 0.3642 | INHERITED FROM: Virulence Factors || Trichothecenes || Zearalenone || 3-acetyldeoxynivalenol || Mycotoxins || Zeranol |
| Class II aaRS and biotin synthetases | 0.3859 | INHERITED FROM: Bacterial Toxins || Lipopolysaccharides |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0.4047 | INHERITED FROM: Endotoxins || Ochratoxins || Lipopolysaccharides |
| PGBD-like | 0.4129 | INHERITED FROM: Arthropod Venoms || Endotoxins || Lipopolysaccharides || Bee Venoms |
| alpha/beta knot | 0.4295 | INHERITED FROM: cylindrospermopsin |
| Histone-fold | 0.4302 | INHERITED FROM: Botulinum Toxins, Type A || Bacterial Toxins || Botulinum Toxins || incobotulinumtoxinA |
| Riboflavin synthase domain-like | 0.4456 | INHERITED FROM: palytoxin || Endotoxins || Marine Toxins || Venoms || Cnidarian Venoms || Lipopolysaccharides |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.4456 | INHERITED FROM: palytoxin || Endotoxins || Marine Toxins || Venoms || Cnidarian Venoms || Lipopolysaccharides |
| Somatomedin B domain | 0.4508 | INHERITED FROM: Botulinum Toxins, Type A || Botulinum Toxins || incobotulinumtoxinA |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.4508 | INHERITED FROM: Endotoxins || Lipopolysaccharides |
| Periplasmic binding protein-like I | 0.4659 | INHERITED FROM: conotoxin GV || Mollusk Venoms |
| TNF-like | 0.468 | INHERITED FROM: brevetoxin 2 || Bacterial Toxins || Endotoxins || Lipopolysaccharides |
| STAT | 0.4989 | INHERITED FROM: Bacterial Toxins || Endotoxins || Lipopolysaccharides |
| E2F-DP heterodimerization region | 0.4989 | INHERITED FROM: Ochratoxins |
| Transcription factor STAT-4 N-domain | 0.4989 | INHERITED FROM: Bacterial Toxins || Endotoxins || Lipopolysaccharides |
| Cation efflux protein transmembrane domain-like | 0.5234 | INHERITED FROM: Ochratoxins |
| Complement control module/SCR domain | 0.5249 | INHERITED FROM: Aflatoxin B1 |
| p53-like transcription factors | 0.5365 | INHERITED FROM: deoxynivalenol || Endotoxins || Trichothecenes || Venoms || Lipopolysaccharides || Bee Venoms || Cytochalasins |
| Hemopexin-like domain | 0.5482 | INHERITED FROM: Arthropod Venoms || Lipopolysaccharides || Bee Venoms |
| Troponin coil-coiled subunits | 0.5559 | INHERITED FROM: Botulinum Toxins, Type A || Botulinum Toxins || incobotulinumtoxinA |
| Thioredoxin-like | 0.5922 | INHERITED FROM: Marine Toxins |
| TIMP-like | 0.5986 | INHERITED FROM: lipopolysaccharide, E. coli O26-B6 || Snake Venoms |
| HLH, helix-loop-helix DNA-binding domain | 0.6092 | INHERITED FROM: azaspiracid |
| 4Fe-4S ferredoxins | 0.6179 | INHERITED FROM: Endotoxins || Lipopolysaccharides |
| Second domain of FERM | 0.6196 | INHERITED FROM: aflatoxin B2 |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.6343 | INHERITED FROM: Zearalenone |
| Metalloproteases ("zincins"), catalytic domain | 0.6408 | INHERITED FROM: Arthropod Venoms || Bee Venoms |
| Leucine zipper domain | 0.6489 | INHERITED FROM: Virulence Factors || Citrinin || Trichothecenes || Ochratoxins || cylindrospermopsin || Lipopolysaccharides |
| Bromodomain | 0.6568 | INHERITED FROM: deoxynivalenol || Trichothecenes |
| Cyclin-like | 0.6597 | INHERITED FROM: Citrinin || Ochratoxins |
| MFS general substrate transporter | 0.6696 | INHERITED FROM: Cytochalasin B |
| SH3-domain | 0.7272 | INHERITED FROM: aflatoxin B2 |
| Cystine-knot cytokines | 0.7302 | INHERITED FROM: Bacterial Toxins || Marine Toxins || Enterotoxins || Zearalenone || Lipopolysaccharides |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.7356 | INHERITED FROM: cylindrospermopsin |
| Nicotinic receptor ligand binding domain-like | 0.7531 | INHERITED FROM: Muscimol || Venoms || Mollusk Venoms |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.7531 | INHERITED FROM: Muscimol || Venoms || Mollusk Venoms |
| Periplasmic binding protein-like II | 0.7924 | INHERITED FROM: conotoxin GV || Mollusk Venoms |
| Arginase/deacetylase | 0.8429 | INHERITED FROM: Viper Venoms || Crotalid Venoms || Snake Venoms || Venoms |
| Growth factor receptor domain | 0.8921 | INHERITED FROM: Botulinum Toxins || incobotulinumtoxinA |
| S15/NS1 RNA-binding domain | 0.8941 | INHERITED FROM: Ochratoxins |
| post-AAA+ oligomerization domain-like | 0.8941 | INHERITED FROM: Botulinum Toxins, Type A || Botulinum Toxins || incobotulinumtoxinA |
| Pectin lyase-like | 0.8941 | INHERITED FROM: Botulinum Toxins, Type A || Botulinum Toxins || incobotulinumtoxinA |
| 4-helical cytokines | 0.8972 | INHERITED FROM: deoxynivalenol || brevetoxin 2 || Virulence Factors || Bacterial Toxins || Endotoxins || enterotoxin F, Staphylococcal || Lipid A || Marine Toxins || Trichothecenes || Enterotoxins || fumonisin B1 || Patulin || Fumonisins || lipopolysaccharide, E coli O55-B5 || Lipopolysaccharides || Cytochalasins |
| L30e-like | 0.9325 | INHERITED FROM: cylindrospermopsin |
| A DNA-binding domain in eukaryotic transcription factors | 0.9532 | INHERITED FROM: deoxynivalenol || Trichothecenes || Venoms |
| KRAB domain (Kruppel-associated box) | 1 | INHERITED FROM: Aflatoxin M1 |
| beta-beta-alpha zinc fingers | 1 | INHERITED FROM: Aflatoxin M1 |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
| Flavoproteins | 0 | Direct |
| ATP-dependent DNA ligase DNA-binding domain | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| Fibrinogen coiled-coil and central regions | 0 | Direct |
| BAG domain | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| PHM/PNGase F | 0 | Direct |
| occludin/ELL-like | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| ITPase-like | 0 | Direct |
| P-domain of calnexin/calreticulin | 0 | Direct |
| p53 tetramerization domain | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | Direct |
| Nitric oxide (NO) synthase oxygenase domain | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| LanC-like | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| PriA/YqbF domain | 0 | Direct |
| MAPEG domain-like | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| N-terminal domain of cbl (N-cbl) | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Hypothetical protein YjiA, C-terminal domain | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| LCCL domain | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | Direct |
| Serum albumin-like | 0 | Direct |
| RGC domain-like | 0 | Direct |
| PUG domain-like | 0 | Direct |
| PAH2 domain | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| MgtE membrane domain-like | 0 | Direct |
| DNA clamp | 0 | Direct |
| AXH domain | 0 | Direct |
| Transglutaminase, two C-terminal domains | 0 | Direct |
| Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
| Indolic compounds 2,3-dioxygenase-like | 0 | Direct |
| FAD-binding/transporter-associated domain-like | 0 | Direct |
| FAD-linked oxidases, C-terminal domain | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| ClpS-like | 0 | Direct |
| FAD-linked oxidoreductase | 0 | Direct |
| AhpD-like | 0 | Direct |
| Phosphofructokinase | 0 | Direct |
| SIS domain | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| TATA-box binding protein-like | 0 | Direct |
| Hairpin loop containing domain-like | 0 | Direct |
| I/LWEQ domain | 0 | Direct |
| Ribosomal protein S18 | 0 | Direct |
| Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
| FAS1 domain | 0 | Direct |
| GINS helical bundle-like | 0 | Direct |
| BolA-like | 0 | Direct |
| DEATH domain | 0.0001159 | Direct |
| Tropomyosin | 0.0008061 | Direct |
| Fibronectin type III | 0.002309 | Inherited |
| Protein kinase-like (PK-like) | 0.002917 | Inherited |
| Cadherin-like | 0.005553 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.009378 | Inherited |
| PH domain-like | 0.03133 | Inherited |
| Caspase-like | 0.03219 | Inherited |
| Bcl-2 inhibitors of programmed cell death | 0.0447 | Inherited |
| Cytokine | 0.04736 | Inherited |
| SMAD/FHA domain | 0.07113 | Inherited |
| GTPase activation domain, GAP | 0.09621 | Inherited |
| Toll/Interleukin receptor TIR domain | 0.1091 | Inherited |
| Voltage-gated potassium channels | 0.1111 | Inherited |
| Polo-box domain | 0.141 | Inherited |
| PDZ domain-like | 0.1412 | Inherited |
| Sema domain | 0.1507 | Inherited |
| Rhodanese/Cell cycle control phosphatase | 0.1521 | Inherited |
| PYP-like sensor domain (PAS domain) | 0.1649 | Inherited |
| EGF/Laminin | 0.1667 | Inherited |
| Fibrinogen C-terminal domain-like | 0.1803 | Inherited |
| Cytochrome P450 | 0.2175 | Inherited |
| DBL homology domain (DH-domain) | 0.2309 | Inherited |
| ABC transporter transmembrane region | 0.2346 | Inherited |
| Cysteine-rich domain | 0.2452 | Inherited |
| Metallothionein | 0.2943 | Inherited |
| Interleukin 8-like chemokines | 0.3122 | Inherited |
| WW domain | 0.3316 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.3454 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.35 | Inherited |
| TNF receptor-like | 0.3538 | Inherited |
| Nuclear receptor ligand-binding domain | 0.3642 | Inherited |
| Class II aaRS and biotin synthetases | 0.3859 | Inherited |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0.4047 | Inherited |
| PGBD-like | 0.4129 | Inherited |
| alpha/beta knot | 0.4295 | Inherited |
| Histone-fold | 0.4302 | Inherited |
| Riboflavin synthase domain-like | 0.4456 | Inherited |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.4456 | Inherited |
| Somatomedin B domain | 0.4508 | Inherited |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.4508 | Inherited |
| Periplasmic binding protein-like I | 0.4659 | Inherited |
| TNF-like | 0.468 | Inherited |
| STAT | 0.4989 | Inherited |
| E2F-DP heterodimerization region | 0.4989 | Inherited |
| Transcription factor STAT-4 N-domain | 0.4989 | Inherited |
| Cation efflux protein transmembrane domain-like | 0.5234 | Inherited |
| Complement control module/SCR domain | 0.5249 | Inherited |
| p53-like transcription factors | 0.5365 | Inherited |
| Hemopexin-like domain | 0.5482 | Inherited |
| Troponin coil-coiled subunits | 0.5559 | Inherited |
| Thioredoxin-like | 0.5922 | Inherited |
| TIMP-like | 0.5986 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.6092 | Inherited |
| 4Fe-4S ferredoxins | 0.6179 | Inherited |
| Second domain of FERM | 0.6196 | Inherited |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.6343 | Inherited |
| Metalloproteases ("zincins"), catalytic domain | 0.6408 | Inherited |
| Leucine zipper domain | 0.6489 | Inherited |
| Bromodomain | 0.6568 | Inherited |
| Cyclin-like | 0.6597 | Inherited |
| MFS general substrate transporter | 0.6696 | Inherited |
| SH3-domain | 0.7272 | Inherited |
| Cystine-knot cytokines | 0.7302 | Inherited |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.7356 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.7531 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.7531 | Inherited |
| Periplasmic binding protein-like II | 0.7924 | Inherited |
| Arginase/deacetylase | 0.8429 | Inherited |
| Growth factor receptor domain | 0.8921 | Inherited |
| S15/NS1 RNA-binding domain | 0.8941 | Inherited |
| post-AAA+ oligomerization domain-like | 0.8941 | Inherited |
| Pectin lyase-like | 0.8941 | Inherited |
| 4-helical cytokines | 0.8972 | Inherited |
| L30e-like | 0.9325 | Inherited |
| A DNA-binding domain in eukaryotic transcription factors | 0.9532 | Inherited |
| KRAB domain (Kruppel-associated box) | 1 | Inherited |
| beta-beta-alpha zinc fingers | 1 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Duplex) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
82153,82153
82153 - FAS1 domain
82153 - FAS1 domain | 0 | DIRECT |
57184,82895
57184 - Growth factor receptor domain
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
55550,55550
55550 - SH2 domain
55550 - SH2 domain | 0 | DIRECT |
51045,47473
51045 - WW domain
47473 - EF-hand | 0 | DIRECT |
49899,57424
49899 - Concanavalin A-like lectins/glucanases
57424 - LDL receptor-like module | 0 | DIRECT |
82199,57667
82199 - SET domain
57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
50156,52540
50156 - PDZ domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
46966,51045
46966 - Spectrin repeat
51045 - WW domain | 0 | DIRECT |
53784,53784
53784 - Phosphofructokinase
53784 - Phosphofructokinase | 0 | DIRECT |
56176,55103
56176 - FAD-binding/transporter-associated domain-like
55103 - FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
49265,56112
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
49742,49742
49742 - PHM/PNGase F
49742 - PHM/PNGase F | 0 | DIRECT |
52025,53187
52025 - PA domain
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
48452,48403
48452 - TPR-like
48403 - Ankyrin repeat | 0 | DIRECT |
57196,90193
57196 - EGF/Laminin
90193 - Notch domain | 0 | DIRECT |
49309,49309
49309 - Transglutaminase, two C-terminal domains
49309 - Transglutaminase, two C-terminal domains | 0 | DIRECT |
57414,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like | 0 | DIRECT |
48552,48552
48552 - Serum albumin-like
48552 - Serum albumin-like | 0 | DIRECT |
57184,49265
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | DIRECT |
53187,47672
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | DIRECT |
49854,57196
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin | 0 | DIRECT |
55945,55945
55945 - TATA-box binding protein-like
55945 - TATA-box binding protein-like | 0 | DIRECT |
50729,50156
50729 - PH domain-like
50156 - PDZ domain-like | 0 | DIRECT |
52540,90002
52540 - P-loop containing nucleoside triphosphate hydrolases
90002 - Hypothetical protein YjiA, C-terminal domain | 0 | DIRECT |
81296,54001
81296 - E set domains
54001 - Cysteine proteinases | 0 | DIRECT |
52058,52047
52058 - L domain-like
52047 - RNI-like | 0 | DIRECT |
82109,82109
82109 - MIR domain
82109 - MIR domain | 0 | DIRECT |
48726,82895
48726 - Immunoglobulin
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
47986,47986
47986 - DEATH domain
47986 - DEATH domain | 0 | DIRECT |
46689,57667
46689 - Homeodomain-like
57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
53300,53300
53300 - vWA-like
53300 - vWA-like | 0 | DIRECT |
82895,57424
82895 - TSP-1 type 1 repeat
57424 - LDL receptor-like module | 0 | DIRECT |
57424,49899
57424 - LDL receptor-like module
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
54909,54909
54909 - Dimeric alpha+beta barrel
54909 - Dimeric alpha+beta barrel | 0 | DIRECT |
57535,50494
57535 - Complement control module/SCR domain
50494 - Trypsin-like serine proteases | 0 | DIRECT |
57196,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain | 0 | DIRECT |
50729,49562
50729 - PH domain-like
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
48403,48452
48403 - Ankyrin repeat
48452 - TPR-like | 0 | DIRECT |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
54001,49309
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains | 0 | DIRECT |
117018,56091
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
81995,81811
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | DIRECT |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | DIRECT |
57424,57196
57424 - LDL receptor-like module
57196 - EGF/Laminin | 0 | DIRECT |
57184,49899
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
49417,47719
49417 - p53-like transcription factors
47719 - p53 tetramerization domain | 0 | DIRECT |
46565,57938
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
57196,49265
57196 - EGF/Laminin
49265 - Fibronectin type III | 0 | DIRECT |
117839,117839
117839 - WWE domain
117839 - WWE domain | 0 | DIRECT |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
53927,53927
53927 - Cytidine deaminase-like
53927 - Cytidine deaminase-like | 0 | DIRECT |
57667,90229
57667 - beta-beta-alpha zinc fingers
90229 - CCCH zinc finger | 0 | DIRECT |
56112,50729
56112 - Protein kinase-like (PK-like)
50729 - PH domain-like | 0 | DIRECT |
49265,53300
49265 - Fibronectin type III
53300 - vWA-like | 0 | DIRECT |
57889,49562
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
57440,50494
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
47668,47473
47668 - N-terminal domain of cbl (N-cbl)
47473 - EF-hand | 0 | DIRECT |
54236,50729
54236 - Ubiquitin-like
50729 - PH domain-like | 0 | DIRECT |
49562,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain | 0 | DIRECT |
57196,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
52540,-7
52540 - P-loop containing nucleoside triphosphate hydrolases
-7 - CATH | 0 | DIRECT |
48366,47473
48366 - Ras GEF
47473 - EF-hand | 0 | DIRECT |
57603,82895
57603 - FnI-like domain
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
54826,51604
54826 - Enolase N-terminal domain-like
51604 - Enolase C-terminal domain-like | 0 | DIRECT |
52087,48350
52087 - CRAL/TRIO domain
48350 - GTPase activation domain, GAP | 0 | DIRECT |
81296,48239
81296 - E set domains
48239 - Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
48350,55961
48350 - GTPase activation domain, GAP
55961 - Bet v1-like | 0 | DIRECT |
100934,100934
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
49899,63887
49899 - Concanavalin A-like lectins/glucanases
63887 - P-domain of calnexin/calreticulin | 0 | DIRECT |
47473,55550
47473 - EF-hand
55550 - SH2 domain | 0 | DIRECT |
55550,57850
55550 - SH2 domain
57850 - RING/U-box | 0 | DIRECT |
81324,81327
81324 - Voltage-gated potassium channels
81327 - Small-conductance potassium channel | 0 | DIRECT |
53300,69318
53300 - vWA-like
69318 - Integrin alpha N-terminal domain | 0 | DIRECT |
161093,161093
161093 - MgtE membrane domain-like
161093 - MgtE membrane domain-like | 0 | DIRECT |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
90188,90188
90188 - Somatomedin B domain
90188 - Somatomedin B domain | 0 | DIRECT |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | DIRECT |
47473,57889
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | DIRECT |
82109,100909
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
49265,56496
49265 - Fibronectin type III
56496 - Fibrinogen C-terminal domain-like | 0 | DIRECT |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
69572,69572
69572 - Activating enzymes of the ubiquitin-like proteins
69572 - Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
90188,53649
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | DIRECT |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | DIRECT |
52980,47781
52980 - Restriction endonuclease-like
47781 - RuvA domain 2-like | 0 | DIRECT |
57667,140996
57667 - beta-beta-alpha zinc fingers
140996 - Hermes dimerisation domain | 0 | DIRECT |
48726,56112
48726 - Immunoglobulin
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56801,56801
56801 - Acetyl-CoA synthetase-like
56801 - Acetyl-CoA synthetase-like | 0 | DIRECT |
55021,56534
55021 - ACT-like
56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | DIRECT |
103575,81296
103575 - Plexin repeat
81296 - E set domains | 0 | DIRECT |
53300,81995
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24 | 0 | DIRECT |
49503,110083
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
50044,48065
50044 - SH3-domain
48065 - DBL homology domain (DH-domain) | 0 | DIRECT |
-7,56112
-7 - CATH
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
110083,55909
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | DIRECT |
52540,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain | 0 | DIRECT |
103637,103637
103637 - CCHHC domain
103637 - CCHHC domain | 0 | DIRECT |
47459,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain) | 0.00189 | INHERITED FROM: Mycotoxins |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0.006752 | INHERITED FROM: Aflatoxins |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.01261 | INHERITED FROM: Botulinum Toxins, Type A || aflatoxin B2 || incobotulinumtoxinA |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.02184 | INHERITED FROM: candoxin || Lipopolysaccharides |
57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like | 0.03628 | INHERITED FROM: lipopolysaccharide, E. coli O26-B6 || Melitten || Venoms || Lipopolysaccharides || Bee Venoms |
49899,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0.03628 | INHERITED FROM: aflatoxin B2 |
47986,52129
47986 - DEATH domain
52129 - Caspase-like | 0.04738 | INHERITED FROM: Bacterial Toxins || Endotoxins || Snake Venoms || Venoms || Lipopolysaccharides |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0.0856 | INHERITED FROM: Mycotoxins |
57440,57440
57440 - Kringle-like
57440 - Kringle-like | 0.1134 | INHERITED FROM: Lipopolysaccharides |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.1338 | INHERITED FROM: aflatoxin B2 |
90257,90257
90257 - Myosin rod fragments
90257 - Myosin rod fragments | 0.1442 | INHERITED FROM: Botulinum Toxins, Type A || Botulinum Toxins || incobotulinumtoxinA |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0.1507 | INHERITED FROM: Mycotoxins |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0.1726 | INHERITED FROM: Aflatoxin B1 || Aflatoxins |
63501,50242
63501 - Frizzled cysteine-rich domain
50242 - TIMP-like | 0.1997 | INHERITED FROM: Botulinum Toxins, Type A || Botulinum Toxins || incobotulinumtoxinA |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.2346 | INHERITED FROM: Zeranol || zearalenol |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0.2608 | INHERITED FROM: aflatoxin B2 |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0.2809 | INHERITED FROM: Bacterial Toxins |
52821,52799
52821 - Rhodanese/Cell cycle control phosphatase
52799 - (Phosphotyrosine protein) phosphatases II | 0.3271 | INHERITED FROM: Trichothecenes || cylindrospermopsin |
49417,81296
49417 - p53-like transcription factors
81296 - E set domains | 0.3645 | INHERITED FROM: deoxynivalenol || Bacterial Toxins || Endotoxins || Trichothecenes || lipopolysaccharide, E. coli O26-B6 || Lipopolysaccharides |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0.4047 | INHERITED FROM: Endotoxins || Ochratoxins || Lipopolysaccharides |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0.4129 | INHERITED FROM: Arthropod Venoms || Endotoxins || Lipopolysaccharides || Bee Venoms |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0.4508 | INHERITED FROM: Ochratoxins |
47655,49417
47655 - STAT
49417 - p53-like transcription factors | 0.4989 | INHERITED FROM: Bacterial Toxins || Endotoxins || Lipopolysaccharides |
46785,144074
46785 - "Winged helix" DNA-binding domain
144074 - E2F-DP heterodimerization region | 0.4989 | INHERITED FROM: Ochratoxins |
53822,53850
53822 - Periplasmic binding protein-like I
53850 - Periplasmic binding protein-like II | 0.4989 | INHERITED FROM: Marine Toxins || conotoxin GV || Venoms || Mollusk Venoms |
49417,55550
49417 - p53-like transcription factors
55550 - SH2 domain | 0.4989 | INHERITED FROM: Bacterial Toxins || Endotoxins || Lipopolysaccharides |
48092,47655
48092 - Transcription factor STAT-4 N-domain
47655 - STAT | 0.4989 | INHERITED FROM: Bacterial Toxins || Endotoxins || Lipopolysaccharides |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.5386 | INHERITED FROM: Mycotoxins |
47113,-7
47113 - Histone-fold
-7 - CATH | 0.5537 | INHERITED FROM: Botulinum Toxins, Type A || Bacterial Toxins || incobotulinumtoxinA |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0.5968 | INHERITED FROM: Trichothecenes || Zearalenone || 3-acetyldeoxynivalenol |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.6179 | INHERITED FROM: Endotoxins || Ochratoxins || Lipopolysaccharides |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0.6245 | INHERITED FROM: Marine Toxins |
53300,49899
53300 - vWA-like
49899 - Concanavalin A-like lectins/glucanases | 0.6866 | INHERITED FROM: Bacterial Toxins |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0.712 | INHERITED FROM: Endotoxins |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.7531 | INHERITED FROM: Muscimol || Venoms || Mollusk Venoms |
47454,57959
47454 - A DNA-binding domain in eukaryotic transcription factors
57959 - Leucine zipper domain | 0.8429 | INHERITED FROM: deoxynivalenol || Trichothecenes || Venoms |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0.8941 | INHERITED FROM: Botulinum Toxins, Type A || Botulinum Toxins || incobotulinumtoxinA |
109640,57667
109640 - KRAB domain (Kruppel-associated box)
57667 - beta-beta-alpha zinc fingers | 1 | INHERITED FROM: Aflatoxin M1 |
57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 1 | INHERITED FROM: Aflatoxin M1 |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
82153,82153
82153 - FAS1 domain
82153 - FAS1 domain | 0 | Direct |
57184,82895
57184 - Growth factor receptor domain
82895 - TSP-1 type 1 repeat | 0 | Direct |
55550,55550
55550 - SH2 domain
55550 - SH2 domain | 0 | Direct |
51045,47473
51045 - WW domain
47473 - EF-hand | 0 | Direct |
49899,57424
49899 - Concanavalin A-like lectins/glucanases
57424 - LDL receptor-like module | 0 | Direct |
82199,57667
82199 - SET domain
57667 - beta-beta-alpha zinc fingers | 0 | Direct |
50156,52540
50156 - PDZ domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
46966,51045
46966 - Spectrin repeat
51045 - WW domain | 0 | Direct |
53784,53784
53784 - Phosphofructokinase
53784 - Phosphofructokinase | 0 | Direct |
56176,55103
56176 - FAD-binding/transporter-associated domain-like
55103 - FAD-linked oxidases, C-terminal domain | 0 | Direct |
49265,56112
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | Direct |
49742,49742
49742 - PHM/PNGase F
49742 - PHM/PNGase F | 0 | Direct |
52025,53187
52025 - PA domain
53187 - Zn-dependent exopeptidases | 0 | Direct |
48452,48403
48452 - TPR-like
48403 - Ankyrin repeat | 0 | Direct |
57196,90193
57196 - EGF/Laminin
90193 - Notch domain | 0 | Direct |
49309,49309
49309 - Transglutaminase, two C-terminal domains
49309 - Transglutaminase, two C-terminal domains | 0 | Direct |
57414,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like | 0 | Direct |
48552,48552
48552 - Serum albumin-like
48552 - Serum albumin-like | 0 | Direct |
57184,49265
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | Direct |
53187,47672
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | Direct |
49854,57196
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin | 0 | Direct |
55945,55945
55945 - TATA-box binding protein-like
55945 - TATA-box binding protein-like | 0 | Direct |
50729,50156
50729 - PH domain-like
50156 - PDZ domain-like | 0 | Direct |
52540,90002
52540 - P-loop containing nucleoside triphosphate hydrolases
90002 - Hypothetical protein YjiA, C-terminal domain | 0 | Direct |
81296,54001
81296 - E set domains
54001 - Cysteine proteinases | 0 | Direct |
52058,52047
52058 - L domain-like
52047 - RNI-like | 0 | Direct |
82109,82109
82109 - MIR domain
82109 - MIR domain | 0 | Direct |
48726,82895
48726 - Immunoglobulin
82895 - TSP-1 type 1 repeat | 0 | Direct |
47986,47986
47986 - DEATH domain
47986 - DEATH domain | 0 | Direct |
46689,57667
46689 - Homeodomain-like
57667 - beta-beta-alpha zinc fingers | 0 | Direct |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
53300,53300
53300 - vWA-like
53300 - vWA-like | 0 | Direct |
82895,57424
82895 - TSP-1 type 1 repeat
57424 - LDL receptor-like module | 0 | Direct |
57424,49899
57424 - LDL receptor-like module
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
54909,54909
54909 - Dimeric alpha+beta barrel
54909 - Dimeric alpha+beta barrel | 0 | Direct |
57535,50494
57535 - Complement control module/SCR domain
50494 - Trypsin-like serine proteases | 0 | Direct |
57196,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain | 0 | Direct |
50729,49562
50729 - PH domain-like
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
48403,48452
48403 - Ankyrin repeat
48452 - TPR-like | 0 | Direct |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | Direct |
54001,49309
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains | 0 | Direct |
117018,56091
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
81995,81811
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | Direct |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | Direct |
57424,57196
57424 - LDL receptor-like module
57196 - EGF/Laminin | 0 | Direct |
57184,49899
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
49417,47719
49417 - p53-like transcription factors
47719 - p53 tetramerization domain | 0 | Direct |
46565,57938
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
57196,49265
57196 - EGF/Laminin
49265 - Fibronectin type III | 0 | Direct |
117839,117839
117839 - WWE domain
117839 - WWE domain | 0 | Direct |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
53927,53927
53927 - Cytidine deaminase-like
53927 - Cytidine deaminase-like | 0 | Direct |
57667,90229
57667 - beta-beta-alpha zinc fingers
90229 - CCCH zinc finger | 0 | Direct |
56112,50729
56112 - Protein kinase-like (PK-like)
50729 - PH domain-like | 0 | Direct |
49265,53300
49265 - Fibronectin type III
53300 - vWA-like | 0 | Direct |
57889,49562
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
57440,50494
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | Direct |
47668,47473
47668 - N-terminal domain of cbl (N-cbl)
47473 - EF-hand | 0 | Direct |
54236,50729
54236 - Ubiquitin-like
50729 - PH domain-like | 0 | Direct |
49562,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain | 0 | Direct |
57196,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | Direct |
52540,-7
52540 - P-loop containing nucleoside triphosphate hydrolases
-7 - CATH | 0 | Direct |
48366,47473
48366 - Ras GEF
47473 - EF-hand | 0 | Direct |
57603,82895
57603 - FnI-like domain
82895 - TSP-1 type 1 repeat | 0 | Direct |
54826,51604
54826 - Enolase N-terminal domain-like
51604 - Enolase C-terminal domain-like | 0 | Direct |
52087,48350
52087 - CRAL/TRIO domain
48350 - GTPase activation domain, GAP | 0 | Direct |
81296,48239
81296 - E set domains
48239 - Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
48350,55961
48350 - GTPase activation domain, GAP
55961 - Bet v1-like | 0 | Direct |
100934,100934
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
49899,63887
49899 - Concanavalin A-like lectins/glucanases
63887 - P-domain of calnexin/calreticulin | 0 | Direct |
47473,55550
47473 - EF-hand
55550 - SH2 domain | 0 | Direct |
55550,57850
55550 - SH2 domain
57850 - RING/U-box | 0 | Direct |
81324,81327
81324 - Voltage-gated potassium channels
81327 - Small-conductance potassium channel | 0 | Direct |
53300,69318
53300 - vWA-like
69318 - Integrin alpha N-terminal domain | 0 | Direct |
161093,161093
161093 - MgtE membrane domain-like
161093 - MgtE membrane domain-like | 0 | Direct |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
90188,90188
90188 - Somatomedin B domain
90188 - Somatomedin B domain | 0 | Direct |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | Direct |
47473,57889
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | Direct |
82109,100909
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
49265,56496
49265 - Fibronectin type III
56496 - Fibrinogen C-terminal domain-like | 0 | Direct |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
69572,69572
69572 - Activating enzymes of the ubiquitin-like proteins
69572 - Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
90188,53649
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | Direct |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | Direct |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | Direct |
52980,47781
52980 - Restriction endonuclease-like
47781 - RuvA domain 2-like | 0 | Direct |
57667,140996
57667 - beta-beta-alpha zinc fingers
140996 - Hermes dimerisation domain | 0 | Direct |
48726,56112
48726 - Immunoglobulin
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56801,56801
56801 - Acetyl-CoA synthetase-like
56801 - Acetyl-CoA synthetase-like | 0 | Direct |
55021,56534
55021 - ACT-like
56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | Direct |
103575,81296
103575 - Plexin repeat
81296 - E set domains | 0 | Direct |
53300,81995
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24 | 0 | Direct |
49503,110083
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
50044,48065
50044 - SH3-domain
48065 - DBL homology domain (DH-domain) | 0 | Direct |
-7,56112
-7 - CATH
56112 - Protein kinase-like (PK-like) | 0 | Direct |
110083,55909
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | Direct |
52540,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain | 0 | Direct |
103637,103637
103637 - CCHHC domain
103637 - CCHHC domain | 0 | Direct |
47459,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain) | 0.00189 | Inherited |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0.006752 | Inherited |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.01261 | Inherited |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.02184 | Inherited |
57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like | 0.03628 | Inherited |
49899,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0.03628 | Inherited |
47986,52129
47986 - DEATH domain
52129 - Caspase-like | 0.04738 | Inherited |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0.0856 | Inherited |
57440,57440
57440 - Kringle-like
57440 - Kringle-like | 0.1134 | Inherited |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.1338 | Inherited |
90257,90257
90257 - Myosin rod fragments
90257 - Myosin rod fragments | 0.1442 | Inherited |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0.1507 | Inherited |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0.1726 | Inherited |
63501,50242
63501 - Frizzled cysteine-rich domain
50242 - TIMP-like | 0.1997 | Inherited |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.2346 | Inherited |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0.2608 | Inherited |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0.2809 | Inherited |
52821,52799
52821 - Rhodanese/Cell cycle control phosphatase
52799 - (Phosphotyrosine protein) phosphatases II | 0.3271 | Inherited |
49417,81296
49417 - p53-like transcription factors
81296 - E set domains | 0.3645 | Inherited |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0.4047 | Inherited |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0.4129 | Inherited |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0.4508 | Inherited |
47655,49417
47655 - STAT
49417 - p53-like transcription factors | 0.4989 | Inherited |
46785,144074
46785 - "Winged helix" DNA-binding domain
144074 - E2F-DP heterodimerization region | 0.4989 | Inherited |
53822,53850
53822 - Periplasmic binding protein-like I
53850 - Periplasmic binding protein-like II | 0.4989 | Inherited |
49417,55550
49417 - p53-like transcription factors
55550 - SH2 domain | 0.4989 | Inherited |
48092,47655
48092 - Transcription factor STAT-4 N-domain
47655 - STAT | 0.4989 | Inherited |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.5386 | Inherited |
47113,-7
47113 - Histone-fold
-7 - CATH | 0.5537 | Inherited |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0.5968 | Inherited |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.6179 | Inherited |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0.6245 | Inherited |
53300,49899
53300 - vWA-like
49899 - Concanavalin A-like lectins/glucanases | 0.6866 | Inherited |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0.712 | Inherited |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.7531 | Inherited |
47454,57959
47454 - A DNA-binding domain in eukaryotic transcription factors
57959 - Leucine zipper domain | 0.8429 | Inherited |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0.8941 | Inherited |
109640,57667
109640 - KRAB domain (Kruppel-associated box)
57667 - beta-beta-alpha zinc fingers | 1 | Inherited |
57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 1 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Triple) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
47459,55785,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
47473,47473,47473
47473 - EF-hand
47473 - EF-hand
47473 - EF-hand | 0 | DIRECT |
53300,69318,69179
53300 - vWA-like
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains | 0 | DIRECT |
81296,54001,49309
81296 - E set domains
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains | 0 | DIRECT |
52540,51045,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain
51045 - WW domain | 0 | DIRECT |
57424,57424,57196
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57196 - EGF/Laminin | 0 | DIRECT |
47473,57889,57889
47473 - EF-hand
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
49899,57196,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
57196,57184,49899
57196 - EGF/Laminin
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
47668,47473,55550
47668 - N-terminal domain of cbl (N-cbl)
47473 - EF-hand
55550 - SH2 domain | 0 | DIRECT |
50729,50729,57863
50729 - PH domain-like
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | DIRECT |
103575,81296,81296
103575 - Plexin repeat
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
57424,57196,57196
57424 - LDL receptor-like module
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
48726,48726,82895
48726 - Immunoglobulin
48726 - Immunoglobulin
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
48726,82895,82895
48726 - Immunoglobulin
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
49503,110083,55909
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | DIRECT |
57196,49854,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
47473,55550,57850
47473 - EF-hand
55550 - SH2 domain
57850 - RING/U-box | 0 | DIRECT |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
81995,81811,82754
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
50156,50729,50729
50156 - PDZ domain-like
50729 - PH domain-like
50729 - PH domain-like | 0 | DIRECT |
46565,57938,49493
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
53300,81995,81811
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | DIRECT |
47986,47986,52129
47986 - DEATH domain
47986 - DEATH domain
52129 - Caspase-like | 0 | DIRECT |
49265,49265,53300
49265 - Fibronectin type III
49265 - Fibronectin type III
53300 - vWA-like | 0 | DIRECT |
49854,57196,49854
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
54001,49309,49309
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains
49309 - Transglutaminase, two C-terminal domains | 0 | DIRECT |
57196,57535,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
57196,57196,63825
57196 - EGF/Laminin
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
48726,49265,56112
48726 - Immunoglobulin
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
51045,47473,47473
51045 - WW domain
47473 - EF-hand
47473 - EF-hand | 0 | DIRECT |
64268,50044,50044
64268 - PX domain
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
82199,57667,57667
82199 - SET domain
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
82109,82109,100909
82109 - MIR domain
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
57535,57535,50494
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
50494 - Trypsin-like serine proteases | 0 | DIRECT |
57889,57889,49562
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
57184,49899,49899
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
52743,49785,57184
52743 - Subtilisin-like
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
46966,46966,51045
46966 - Spectrin repeat
46966 - Spectrin repeat
51045 - WW domain | 0 | DIRECT |
57196,49854,57535
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
52540,52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
57440,57440,50494
57440 - Kringle-like
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
75399,75399,75399
75399 - Plakin repeat
75399 - Plakin repeat
75399 - Plakin repeat | 0 | DIRECT |
46966,51045,47473
46966 - Spectrin repeat
51045 - WW domain
47473 - EF-hand | 0 | DIRECT |
103657,50729,48350
103657 - BAR/IMD domain-like
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | DIRECT |
90188,90188,53649
90188 - Somatomedin B domain
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | DIRECT |
49562,57889,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
48552,48552,48552
48552 - Serum albumin-like
48552 - Serum albumin-like
48552 - Serum albumin-like | 0 | DIRECT |
103637,103637,103637
103637 - CCHHC domain
103637 - CCHHC domain
103637 - CCHHC domain | 0 | DIRECT |
47473,47473,57889
47473 - EF-hand
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | DIRECT |
52058,48726,48726
52058 - L domain-like
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
49899,57424,49899
49899 - Concanavalin A-like lectins/glucanases
57424 - LDL receptor-like module
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
50729,50729,48350
50729 - PH domain-like
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | DIRECT |
49265,48726,49265
49265 - Fibronectin type III
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | DIRECT |
57924,57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
52025,53187,47672
52025 - PA domain
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | DIRECT |
57184,57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
53067,53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | DIRECT |
57414,57440,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like
57440 - Kringle-like | 0 | DIRECT |
57196,57196,90193
57196 - EGF/Laminin
57196 - EGF/Laminin
90193 - Notch domain | 0 | DIRECT |
50044,48065,50729
50044 - SH3-domain
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | DIRECT |
50156,52540,51045
50156 - PDZ domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain | 0 | DIRECT |
49265,48726,48726
49265 - Fibronectin type III
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
117018,56091,50249
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
54768,54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
48366,47473,57889
48366 - Ras GEF
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | DIRECT |
50729,49562,48350
50729 - PH domain-like
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48350 - GTPase activation domain, GAP | 0 | DIRECT |
47220,47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
53300,53300,53300
53300 - vWA-like
53300 - vWA-like
53300 - vWA-like | 0 | DIRECT |
50729,50156,50156
50729 - PH domain-like
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | DIRECT |
51338,51556,51338
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
49785,57184,49265
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | DIRECT |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.00006109 | DIRECT |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0.00259 | INHERITED FROM: Aflatoxins |
57586,57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like
57586 - TNF receptor-like | 0.06871 | INHERITED FROM: lipopolysaccharide, E. coli O26-B6 |
57196,57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.07014 | INHERITED FROM: Aflatoxin B1 || Mycotoxins |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0.1507 | INHERITED FROM: aflatoxin B2 || Mycotoxins |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0.4047 | INHERITED FROM: Endotoxins || Ochratoxins || Lipopolysaccharides |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0.4508 | INHERITED FROM: Ochratoxins |
47655,49417,55550
47655 - STAT
49417 - p53-like transcription factors
55550 - SH2 domain | 0.4989 | INHERITED FROM: Bacterial Toxins || Endotoxins || Lipopolysaccharides |
48092,47655,49417
48092 - Transcription factor STAT-4 N-domain
47655 - STAT
49417 - p53-like transcription factors | 0.4989 | INHERITED FROM: Bacterial Toxins || Endotoxins || Lipopolysaccharides |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0.5148 | INHERITED FROM: Endotoxins || Lipopolysaccharides |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.6179 | INHERITED FROM: Endotoxins || Ochratoxins || Lipopolysaccharides |
109640,57667,57667
109640 - KRAB domain (Kruppel-associated box)
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0.9647 | INHERITED FROM: Aflatoxin M1 |
57667,57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 1 | INHERITED FROM: Aflatoxin M1 |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
47459,55785,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
47473,47473,47473
47473 - EF-hand
47473 - EF-hand
47473 - EF-hand | 0 | Direct |
53300,69318,69179
53300 - vWA-like
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains | 0 | Direct |
81296,54001,49309
81296 - E set domains
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains | 0 | Direct |
52540,51045,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain
51045 - WW domain | 0 | Direct |
57424,57424,57196
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57196 - EGF/Laminin | 0 | Direct |
47473,57889,57889
47473 - EF-hand
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
49899,57196,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
57196,57184,49899
57196 - EGF/Laminin
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
47668,47473,55550
47668 - N-terminal domain of cbl (N-cbl)
47473 - EF-hand
55550 - SH2 domain | 0 | Direct |
50729,50729,57863
50729 - PH domain-like
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | Direct |
103575,81296,81296
103575 - Plexin repeat
81296 - E set domains
81296 - E set domains | 0 | Direct |
57424,57196,57196
57424 - LDL receptor-like module
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
48726,48726,82895
48726 - Immunoglobulin
48726 - Immunoglobulin
82895 - TSP-1 type 1 repeat | 0 | Direct |
48726,82895,82895
48726 - Immunoglobulin
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
49503,110083,55909
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | Direct |
57196,49854,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
47473,55550,57850
47473 - EF-hand
55550 - SH2 domain
57850 - RING/U-box | 0 | Direct |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
81995,81811,82754
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
50156,50729,50729
50156 - PDZ domain-like
50729 - PH domain-like
50729 - PH domain-like | 0 | Direct |
46565,57938,49493
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
53300,81995,81811
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | Direct |
47986,47986,52129
47986 - DEATH domain
47986 - DEATH domain
52129 - Caspase-like | 0 | Direct |
49265,49265,53300
49265 - Fibronectin type III
49265 - Fibronectin type III
53300 - vWA-like | 0 | Direct |
49854,57196,49854
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | Direct |
54001,49309,49309
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains
49309 - Transglutaminase, two C-terminal domains | 0 | Direct |
57196,57535,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
57196,57196,63825
57196 - EGF/Laminin
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
48726,49265,56112
48726 - Immunoglobulin
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | Direct |
51045,47473,47473
51045 - WW domain
47473 - EF-hand
47473 - EF-hand | 0 | Direct |
64268,50044,50044
64268 - PX domain
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
82199,57667,57667
82199 - SET domain
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0 | Direct |
82109,82109,100909
82109 - MIR domain
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
57535,57535,50494
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
50494 - Trypsin-like serine proteases | 0 | Direct |
57889,57889,49562
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
57184,49899,49899
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
52743,49785,57184
52743 - Subtilisin-like
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | Direct |
46966,46966,51045
46966 - Spectrin repeat
46966 - Spectrin repeat
51045 - WW domain | 0 | Direct |
57196,49854,57535
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | Direct |
52540,52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
57440,57440,50494
57440 - Kringle-like
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | Direct |
75399,75399,75399
75399 - Plakin repeat
75399 - Plakin repeat
75399 - Plakin repeat | 0 | Direct |
46966,51045,47473
46966 - Spectrin repeat
51045 - WW domain
47473 - EF-hand | 0 | Direct |
103657,50729,48350
103657 - BAR/IMD domain-like
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | Direct |
90188,90188,53649
90188 - Somatomedin B domain
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | Direct |
49562,57889,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
48552,48552,48552
48552 - Serum albumin-like
48552 - Serum albumin-like
48552 - Serum albumin-like | 0 | Direct |
103637,103637,103637
103637 - CCHHC domain
103637 - CCHHC domain
103637 - CCHHC domain | 0 | Direct |
47473,47473,57889
47473 - EF-hand
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | Direct |
52058,48726,48726
52058 - L domain-like
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | Direct |
49899,57424,49899
49899 - Concanavalin A-like lectins/glucanases
57424 - LDL receptor-like module
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
50729,50729,48350
50729 - PH domain-like
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | Direct |
49265,48726,49265
49265 - Fibronectin type III
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | Direct |
57924,57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
52025,53187,47672
52025 - PA domain
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | Direct |
57184,57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
53067,53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | Direct |
57414,57440,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like
57440 - Kringle-like | 0 | Direct |
57196,57196,90193
57196 - EGF/Laminin
57196 - EGF/Laminin
90193 - Notch domain | 0 | Direct |
50044,48065,50729
50044 - SH3-domain
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | Direct |
50156,52540,51045
50156 - PDZ domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain | 0 | Direct |
49265,48726,48726
49265 - Fibronectin type III
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | Direct |
117018,56091,50249
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
54768,54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
48366,47473,57889
48366 - Ras GEF
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | Direct |
50729,49562,48350
50729 - PH domain-like
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48350 - GTPase activation domain, GAP | 0 | Direct |
47220,47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | Direct |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
53300,53300,53300
53300 - vWA-like
53300 - vWA-like
53300 - vWA-like | 0 | Direct |
50729,50156,50156
50729 - PH domain-like
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | Direct |
51338,51556,51338
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
49785,57184,49265
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | Direct |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.00006109 | Direct |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0.00259 | Inherited |
57586,57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like
57586 - TNF receptor-like | 0.06871 | Inherited |
57196,57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.07014 | Inherited |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0.1507 | Inherited |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0.4047 | Inherited |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0.4508 | Inherited |
47655,49417,55550
47655 - STAT
49417 - p53-like transcription factors
55550 - SH2 domain | 0.4989 | Inherited |
48092,47655,49417
48092 - Transcription factor STAT-4 N-domain
47655 - STAT
49417 - p53-like transcription factors | 0.4989 | Inherited |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0.5148 | Inherited |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.6179 | Inherited |
109640,57667,57667
109640 - KRAB domain (Kruppel-associated box)
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0.9647 | Inherited |
57667,57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 1 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Plot distribution on species Tree Of Life (sTOL) for Superfamily and/or Family domains annotated by this CC term
 |
Plot tree as:
| |
Download Newick format tree:
|
( show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domain
architecture data for all genomes in SUPERFAMILY. The PAUP
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
Plot distribution on species Tree Of Life (sTOL) for single supra-domains annotated by this CC term
|
Plot tree as:
| |
Download Newick format tree:
| |
Browsing in TREE OF LIFE:
|
( show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
|
|
> BO Hierarchy > Toxins, Biological
