DNA polymerase beta-like, second domain family

SCOP classification

• Root: SCOP hierarchy in SUPERFAMILY [ 0] (11)
• Class: All alpha proteins [ 46456] (284)
• Fold: SAM domain-like [ 47768] (16)
• Superfamily: PsbU/PolX domain-like [ 81585] (2)
• Family: DNA polymerase beta-like, second domain [ 81584] (3)

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Family statistics

	Genomes (46)	Uniprot 2018_03 genome	PDB chains (SCOP 1.75)
Domains	124	285	14
Proteins	124	285	14

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Enzyme Commission (EC)

Highlighted in gray are those with FDR_all>0.001

	EC term	FDR (all)	IC level	SDEO level	Annotation (direct or inherited)
Enzyme Commission (EC)	DNA nucleotidylexotransferase	0	2.264	--	DIRECT
Enzyme Commission (EC)	Transferring phosphorous-containing groups	0	0.2728	--	DIRECT
Enzyme Commission (EC)	Transferases	0	0	--	DIRECT
Enzyme Commission (EC)	Nucleotidyltransferases	0	0.6958	Least Informative	DIRECT
Enzyme Commission (EC)	DNA-directed DNA polymerase	0.00000000008333	1.31	Informative	DIRECT

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Mouse Phenotype (MP)

Highlighted in gray are those with FDR_all>0.001

	MP term	FDR (all)	IC level	SDMP level	Annotation (direct or inherited)
Mammalian Phenotype (MP)	abnormal hematopoietic cell number	0	0.8473	--	DIRECT
Mammalian Phenotype (MP)	abnormal immune system morphology	0	0.7223	--	DIRECT
Mammalian Phenotype (MP)	abnormal leukocyte cell number	0	0.9129	--	DIRECT
Mammalian Phenotype (MP)	abnormal mononuclear cell morphology	0	0.8473	--	DIRECT
Mammalian Phenotype (MP)	decreased lymphocyte cell number	0	1.156	--	DIRECT
Mammalian Phenotype (MP)	abnormal immune system cell morphology	0	0.8038	--	DIRECT
Mammalian Phenotype (MP)	abnormal definitive hematopoiesis	0	1.072	--	DIRECT
Mammalian Phenotype (MP)	abnormal lymphocyte morphology	0	0.9404	--	DIRECT
Mammalian Phenotype (MP)	decreased leukocyte cell number	0	1.156	--	DIRECT
Mammalian Phenotype (MP)	abnormal lymphopoiesis	0	1.205	--	DIRECT
Mammalian Phenotype (MP)	abnormal hemopoiesis	0	1.072	--	DIRECT
Mammalian Phenotype (MP)	abnormal hematopoietic cell morphology	0	0.7167	--	DIRECT
Mammalian Phenotype (MP)	abnormal hematopoietic system morphology/development	0	0.6686	--	DIRECT
Mammalian Phenotype (MP)	abnormal leukopoiesis	0	1.156	--	DIRECT
Mammalian Phenotype (MP)	abnormal leukocyte morphology	0	0.8108	--	DIRECT
Mammalian Phenotype (MP)	hematopoietic system phenotype	0	0.5945	Least Informative	DIRECT
Mammalian Phenotype (MP)	immune system phenotype	0	0.5462	Least Informative	DIRECT
Mammalian Phenotype (MP)	abnormal B cell morphology	0	1.156	Moderately Informative	DIRECT
Mammalian Phenotype (MP)	abnormal blood cell morphology/development	0	1.059	Moderately Informative	DIRECT
Mammalian Phenotype (MP)	abnormal blood cell morphology	0	0.9129	Moderately Informative	DIRECT
Mammalian Phenotype (MP)	abnormal lymphocyte cell number	0	1.023	Moderately Informative	DIRECT
Mammalian Phenotype (MP)	decreased hematopoietic cell number	0	1.072	Moderately Informative	DIRECT
Mammalian Phenotype (MP)	abnormal B cell differentiation	0	1.373	Informative	DIRECT
Mammalian Phenotype (MP)	abnormal immunoglobulin V(D)J recombination	0	2.126	Highly Informative	DIRECT

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Enzyme Commission (EC)

Highlighted in gray are those with FDR_all>0.001

	EC term	FDR (all)	IC level	SDEC level	Annotation (direct or inherited)
Enzyme Commission (EC)	Transferring phosphorus-containing groups	0	0.7021	--	DIRECT
Enzyme Commission (EC)	DNA nucleotidylexotransferase	0	2.753	--	DIRECT
Enzyme Commission (EC)	Transferases	0	0.3972	Least Informative	DIRECT
Enzyme Commission (EC)	Nucleotidyltransferases	0	1.126	Moderately Informative	DIRECT
Enzyme Commission (EC)	DNA-directed DNA polymerase	0.0000000000003579	1.725	Informative	DIRECT

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