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Acting on carbon-nitrogen bonds, other than peptid
(show info)
Enzyme Commission (EC)
Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed. To navigate hierarchical structure of EC, we display all parental EC terms to the current EC term of interest ordered by their shortest distances to the current term. Also, only direct children EC terms of the current EC term are listed.
Structural Classification of Proteins (SCOP)
SCOP classifies evolutionary-related domains into Superfamily level and Family level. Accordingly, we have generated the domain-centric EC annotations for each of the three concepts at each of the two domain levels.
Structural Domain Enzyme Commission Ontology (SDEO)
As domain-centric ontology, SDEO only refers to those EC terms which are the most informative to annotate SCOP domains.
EC annotations for SCOP domains
For details, please visit Documentation: EC annotations for SCOP domains. Therein, we provide several relevant files ( Data Availability) for the download, including an annotation file (i.e., Domain2EC.txt) and the corresponding ontology (i.e., SDEO.txt).
Supra-domain Enzyme Commission Ontology (SPEO)
As an extension, SPEO includes those EC terms which are the most informative to annotate supra-domains and individual SCOP domains at the Superfamily level.
EC annotations for Supra-domains
For details, please visit Documentation: EC annotations for Supra-domains. Therein, we provide several relevant files ( Data Availability) for the download, including a annotation file (i.e., SP2EC.txt) and an ontology (i.e., SPEO.txt). For the sake of being browsable, listed below are those supra-domains (single, dual, triple, quad).
Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]
Root: EC Hierarchy (from IntEnz release 70)
Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this EC term (Not in SDEO)
Highlighted in gray are those with FDR_all>0.001
Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this (SDEO level: Moderately Informative)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| Arginase-like amidino hydrolases | 0 | DIRECT |
| LmbE-like | 0 | DIRECT |
| beta-Lactamase/D-ala carboxypeptidase | 0 | DIRECT |
| alpha-subunit of urease, catalytic domain | 0 | DIRECT |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
| Ureidoglycolate hydrolase AllA | 0 | DIRECT |
| Isochorismatase-like hydrolases | 0 | DIRECT |
| GW domain | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase) | 0 | DIRECT |
| Urease, gamma-subunit | 0 | DIRECT |
| Inosicase | 0 | DIRECT |
| 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB | 0 | DIRECT |
| Putative cyclase | 0 | DIRECT |
| Urease, beta-subunit | 0 | DIRECT |
| dUTPase-like | 0 | DIRECT |
| SAH/MTA deaminase-like | 0 | DIRECT |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
| Transglutaminase core | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, catalytic C-terminal domain | 0 | DIRECT |
| Dimethylarginine dimethylaminohydrolase DDAH | 0 | DIRECT |
| AstE/AspA-like | 0 | DIRECT |
| Porphyromonas-type peptidylarginine deiminase | 0 | DIRECT |
| Deoxycytidylate deaminase-like | 0 | DIRECT |
| Zn metallo-beta-lactamase | 0 | DIRECT |
| Imidazolonepropionase-like | 0 | DIRECT |
| PUG domain | 0 | DIRECT |
| Bacterial dinuclear zinc exopeptidases | 0 | DIRECT |
| Transthyretin (synonym: prealbumin) | 0 | DIRECT |
| CheD-like | 0 | DIRECT |
| Methenyltetrahydromethanopterin cyclohydrolase | 0 | DIRECT |
| Histone deacetylase, HDAC | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, N-terminal domain | 0 | DIRECT |
| Creatininase | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| Extended PAW domain | 0 | DIRECT |
| Archaeal IMP cyclohydrolase PurO | 0 | DIRECT |
| GTP cyclohydrolase I | 0 | DIRECT |
| Adenosine/AMP deaminase | 0 | DIRECT |
| Imidazolonepropionase-like | 0 | DIRECT |
| Glutaminase | 0 | DIRECT |
| NagB-like | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | DIRECT |
| RibA-like | 0 | DIRECT |
| AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC | 0 | DIRECT |
| Tetrahydrofolate dehydrogenase/cyclohydrolase | 0 | DIRECT |
| Dihydroorotase | 0 | DIRECT |
| Allantoicase repeat | 0 | DIRECT |
| alpha-Subunit of urease | 0 | DIRECT |
| Carbamilase | 0 | DIRECT |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Succinylarginine dihydrolase-like | 0 | DIRECT |
| Cytidine deaminase | 0 | DIRECT |
| Penicillin acylase, catalytic domain | 0 | DIRECT |
| Arginine deiminase | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Peptide deformylase | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
| SAH/MTA deaminase-like | 0 | DIRECT |
| HisI-like | 0 | DIRECT |
| Glutaminase/Asparaginase | 0 | DIRECT |
| Putative serine hydrolase Ydr428c | 0 | DIRECT |
| N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain | 0 | DIRECT |
| HCP-like | 0.00000000000002878 | DIRECT |
| (Glycosyl)asparaginase | 0.0000000000004683 | DIRECT |
| RibD C-terminal domain-like | 0.0000000000005455 | DIRECT |
| TENA/THI-4 | 0.00000000006701 | DIRECT |
| Nitrilase | 0.000000827 | DIRECT |
| Peptidoglycan binding domain, PGBD | 0.00001773 | DIRECT |
| NodB-like polysaccharide deacetylase | 0.00008073 | DIRECT |
| Ankyrin repeat | 0.0008188 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0.0009364 | DIRECT |
| LysM domain | 0.003583 | INHERITED FROM: N-acetylmuramoyl-L-alanine amidase || In linear amides |
| HisE-like (PRA-PH) | 0.5141 | INHERITED FROM: In cyclic amidines || Phosphoribosyl-AMP cyclohydrolase |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 0.8809 | INHERITED FROM: Dihydroorotase || In cyclic amides |
| L-histidinol dehydrogenase HisD | 0.9048 | INHERITED FROM: Phosphoribosyl-AMP cyclohydrolase |
| BC N-terminal domain-like | 1 | INHERITED FROM: Dihydroorotase |
| BC ATP-binding domain-like | 1 | INHERITED FROM: Dihydroorotase |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | INHERITED FROM: Dihydroorotase |
| Formyltransferase | 1 | INHERITED FROM: Formyltetrahydrofolate deformylase |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| Arginase-like amidino hydrolases | 0 | Direct |
| LmbE-like | 0 | Direct |
| beta-Lactamase/D-ala carboxypeptidase | 0 | Direct |
| alpha-subunit of urease, catalytic domain | 0 | Direct |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
| Ureidoglycolate hydrolase AllA | 0 | Direct |
| Isochorismatase-like hydrolases | 0 | Direct |
| GW domain | 0 | Direct |
| Hydantoinase (dihydropyrimidinase) | 0 | Direct |
| Urease, gamma-subunit | 0 | Direct |
| Inosicase | 0 | Direct |
| 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB | 0 | Direct |
| Putative cyclase | 0 | Direct |
| Urease, beta-subunit | 0 | Direct |
| dUTPase-like | 0 | Direct |
| SAH/MTA deaminase-like | 0 | Direct |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
| Transglutaminase core | 0 | Direct |
| Peptidylarginine deiminase Pad4, catalytic C-terminal domain | 0 | Direct |
| Dimethylarginine dimethylaminohydrolase DDAH | 0 | Direct |
| AstE/AspA-like | 0 | Direct |
| Porphyromonas-type peptidylarginine deiminase | 0 | Direct |
| Deoxycytidylate deaminase-like | 0 | Direct |
| Zn metallo-beta-lactamase | 0 | Direct |
| Imidazolonepropionase-like | 0 | Direct |
| PUG domain | 0 | Direct |
| Bacterial dinuclear zinc exopeptidases | 0 | Direct |
| Transthyretin (synonym: prealbumin) | 0 | Direct |
| CheD-like | 0 | Direct |
| Methenyltetrahydromethanopterin cyclohydrolase | 0 | Direct |
| Histone deacetylase, HDAC | 0 | Direct |
| Peptidylarginine deiminase Pad4, N-terminal domain | 0 | Direct |
| Creatininase | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| Extended PAW domain | 0 | Direct |
| Archaeal IMP cyclohydrolase PurO | 0 | Direct |
| GTP cyclohydrolase I | 0 | Direct |
| Adenosine/AMP deaminase | 0 | Direct |
| Imidazolonepropionase-like | 0 | Direct |
| Glutaminase | 0 | Direct |
| NagB-like | 0 | Direct |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | Direct |
| RibA-like | 0 | Direct |
| AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC | 0 | Direct |
| Tetrahydrofolate dehydrogenase/cyclohydrolase | 0 | Direct |
| Dihydroorotase | 0 | Direct |
| Allantoicase repeat | 0 | Direct |
| alpha-Subunit of urease | 0 | Direct |
| Carbamilase | 0 | Direct |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | Direct |
| Succinylarginine dihydrolase-like | 0 | Direct |
| Cytidine deaminase | 0 | Direct |
| Penicillin acylase, catalytic domain | 0 | Direct |
| Arginine deiminase | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Peptide deformylase | 0 | Direct |
| Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
| SAH/MTA deaminase-like | 0 | Direct |
| HisI-like | 0 | Direct |
| Glutaminase/Asparaginase | 0 | Direct |
| Putative serine hydrolase Ydr428c | 0 | Direct |
| N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain | 0 | Direct |
| HCP-like | 0.00000000000002878 | Direct |
| (Glycosyl)asparaginase | 0.0000000000004683 | Direct |
| RibD C-terminal domain-like | 0.0000000000005455 | Direct |
| TENA/THI-4 | 0.00000000006701 | Direct |
| Nitrilase | 0.000000827 | Direct |
| Peptidoglycan binding domain, PGBD | 0.00001773 | Direct |
| NodB-like polysaccharide deacetylase | 0.00008073 | Direct |
| Ankyrin repeat | 0.0008188 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0.0009364 | Direct |
| LysM domain | 0.003583 | Inherited |
| HisE-like (PRA-PH) | 0.5141 | Inherited |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 0.8809 | Inherited |
| L-histidinol dehydrogenase HisD | 0.9048 | Inherited |
| BC N-terminal domain-like | 1 | Inherited |
| BC ATP-binding domain-like | 1 | Inherited |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | Inherited |
| Formyltransferase | 1 | Inherited |
Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this EC term
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Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
(show details)
Supra-domains annotated to this EC term (SPEO level: Moderately Informative)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
101386,53720
101386 - all-alpha NTP pyrophosphatases
53720 - ALDH-like | 0 | DIRECT |
53927,53927
53927 - Cytidine deaminase-like
53927 - Cytidine deaminase-like | 0 | DIRECT |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
51278,51338
51278 - Urease, beta-subunit
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
54111,51278
54111 - Urease, gamma-subunit
51278 - Urease, beta-subunit | 0 | DIRECT |
49503,110083
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
56601,52091
56601 - beta-lactamase/transpeptidase-like
52091 - SpoIIaa-like | 0 | DIRECT |
55821,142695
55821 - YrdC/RibB
142695 - RibA-like | 0 | DIRECT |
52768,52768
52768 - Arginase/deacetylase
52768 - Arginase/deacetylase | 0 | DIRECT |
53927,53597
53927 - Cytidine deaminase-like
53597 - Dihydrofolate reductase-like | 0 | DIRECT |
55021,53328
55021 - ACT-like
53328 - Formyltransferase | 0 | DIRECT |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | DIRECT |
53774,48403
53774 - Glutaminase/Asparaginase
48403 - Ankyrin repeat | 0 | DIRECT |
55846,47090
55846 - N-acetylmuramoyl-L-alanine amidase-like
47090 - PGBD-like | 0 | DIRECT |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
54001,49785
54001 - Cysteine proteinases
49785 - Galactose-binding domain-like | 0 | DIRECT |
143503,54001
143503 - PUG domain-like
54001 - Cysteine proteinases | 0 | DIRECT |
56601,48403
56601 - beta-lactamase/transpeptidase-like
48403 - Ankyrin repeat | 0 | DIRECT |
110083,55909
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | DIRECT |
141734,101386
141734 - HisI-like
101386 - all-alpha NTP pyrophosphatases | 0 | DIRECT |
52335,51556
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases | 0.0000001707 | DIRECT |
52317,52440
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain | 0.000004723 | DIRECT |
54106,54001
54106 - LysM domain
54001 - Cysteine proteinases | 0.00001069 | DIRECT |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0.0005074 | DIRECT |
54106,54106
54106 - LysM domain
54106 - LysM domain | 0.01523 | INHERITED FROM: N-acetylmuramoyl-L-alanine amidase || In linear amides |
52021,52317
52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
52317 - Class I glutamine amidotransferase-like | 0.8622 | INHERITED FROM: Dihydroorotase || In cyclic amides |
56059,52335
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like | 0.9575 | INHERITED FROM: Dihydroorotase || In cyclic amides |
48108,52440
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain | 0.997 | INHERITED FROM: Dihydroorotase || In cyclic amides |
53092,55920
53092 - Creatinase/prolidase N-terminal domain
55920 - Creatinase/aminopeptidase | 1 | INHERITED FROM: In linear amidines || Creatinase |
56059,48108
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain | 1 | INHERITED FROM: Dihydroorotase || In cyclic amides |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
101386,53720
101386 - all-alpha NTP pyrophosphatases
53720 - ALDH-like | 0 | Direct |
53927,53927
53927 - Cytidine deaminase-like
53927 - Cytidine deaminase-like | 0 | Direct |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
51278,51338
51278 - Urease, beta-subunit
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
54111,51278
54111 - Urease, gamma-subunit
51278 - Urease, beta-subunit | 0 | Direct |
49503,110083
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
56601,52091
56601 - beta-lactamase/transpeptidase-like
52091 - SpoIIaa-like | 0 | Direct |
55821,142695
55821 - YrdC/RibB
142695 - RibA-like | 0 | Direct |
52768,52768
52768 - Arginase/deacetylase
52768 - Arginase/deacetylase | 0 | Direct |
53927,53597
53927 - Cytidine deaminase-like
53597 - Dihydrofolate reductase-like | 0 | Direct |
55021,53328
55021 - ACT-like
53328 - Formyltransferase | 0 | Direct |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | Direct |
53774,48403
53774 - Glutaminase/Asparaginase
48403 - Ankyrin repeat | 0 | Direct |
55846,47090
55846 - N-acetylmuramoyl-L-alanine amidase-like
47090 - PGBD-like | 0 | Direct |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | Direct |
54001,49785
54001 - Cysteine proteinases
49785 - Galactose-binding domain-like | 0 | Direct |
143503,54001
143503 - PUG domain-like
54001 - Cysteine proteinases | 0 | Direct |
56601,48403
56601 - beta-lactamase/transpeptidase-like
48403 - Ankyrin repeat | 0 | Direct |
110083,55909
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | Direct |
141734,101386
141734 - HisI-like
101386 - all-alpha NTP pyrophosphatases | 0 | Direct |
52335,51556
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases | 0.0000001707 | Direct |
52317,52440
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain | 0.000004723 | Direct |
54106,54001
54106 - LysM domain
54001 - Cysteine proteinases | 0.00001069 | Direct |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0.0005074 | Direct |
54106,54106
54106 - LysM domain
54106 - LysM domain | 0.01523 | Inherited |
52021,52317
52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
52317 - Class I glutamine amidotransferase-like | 0.8622 | Inherited |
56059,52335
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like | 0.9575 | Inherited |
48108,52440
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain | 0.997 | Inherited |
53092,55920
53092 - Creatinase/prolidase N-terminal domain
55920 - Creatinase/aminopeptidase | 1 | Inherited |
56059,48108
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain | 1 | Inherited |
(show details)
Supra-domains annotated to this EC term (SPEO level: Moderately Informative)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
51338,51556,51338
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
51278,51338,51556
51278 - Urease, beta-subunit
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | DIRECT |
49503,110083,55909
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | DIRECT |
141734,101386,53720
141734 - HisI-like
101386 - all-alpha NTP pyrophosphatases
53720 - ALDH-like | 0 | DIRECT |
54111,51278,51338
54111 - Urease, gamma-subunit
51278 - Urease, beta-subunit
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
143503,54001,49785
143503 - PUG domain-like
54001 - Cysteine proteinases
49785 - Galactose-binding domain-like | 0 | DIRECT |
52335,51556,51338
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0.000000006745 | DIRECT |
56059,52335,51556
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases | 0.0000001707 | DIRECT |
52317,52440,56059
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0.000004723 | DIRECT |
52021,52317,52440
52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain | 0.000004723 | DIRECT |
54106,54106,54001
54106 - LysM domain
54106 - LysM domain
54001 - Cysteine proteinases | 0.00001069 | DIRECT |
54106,54106,54106
54106 - LysM domain
54106 - LysM domain
54106 - LysM domain | 0.001622 | INHERITED FROM: N-acetylmuramoyl-L-alanine amidase || In linear amides |
52440,56059,52335
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like | 0.9546 | INHERITED FROM: Dihydroorotase || In cyclic amides |
56059,48108,52440
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain | 0.995 | INHERITED FROM: Dihydroorotase || In cyclic amides |
48108,52440,56059
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0.997 | INHERITED FROM: Dihydroorotase || In cyclic amides |
52440,56059,48108
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain | 1 | INHERITED FROM: Dihydroorotase || In cyclic amides |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
51338,51556,51338
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
51278,51338,51556
51278 - Urease, beta-subunit
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | Direct |
49503,110083,55909
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | Direct |
141734,101386,53720
141734 - HisI-like
101386 - all-alpha NTP pyrophosphatases
53720 - ALDH-like | 0 | Direct |
54111,51278,51338
54111 - Urease, gamma-subunit
51278 - Urease, beta-subunit
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
143503,54001,49785
143503 - PUG domain-like
54001 - Cysteine proteinases
49785 - Galactose-binding domain-like | 0 | Direct |
52335,51556,51338
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0.000000006745 | Direct |
56059,52335,51556
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases | 0.0000001707 | Direct |
52317,52440,56059
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0.000004723 | Direct |
52021,52317,52440
52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain | 0.000004723 | Direct |
54106,54106,54001
54106 - LysM domain
54106 - LysM domain
54001 - Cysteine proteinases | 0.00001069 | Direct |
54106,54106,54106
54106 - LysM domain
54106 - LysM domain
54106 - LysM domain | 0.001622 | Inherited |
52440,56059,52335
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like | 0.9546 | Inherited |
56059,48108,52440
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain | 0.995 | Inherited |
48108,52440,56059
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0.997 | Inherited |
52440,56059,48108
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain | 1 | Inherited |
Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this EC term
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Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
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