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CTD Chemicals (CC): Carbohydrates 
(show info)
Biomedical Ontology
Like Gene Ontology (GO), biomedical ontology such as phenotype ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Biomedical ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI’s thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology Based on YP which is the major contributor to the ‘Ascomycete phenotype ontology’, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- UniProtKB KeyWords (KW) Ontology Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- CTD Diseases (CD) Ontology CD is MEDIC disease vocabulary that is modified by CTD from the "Diseases" [C] branch of Medical Subject Headings (MeSH), combined with genetic disorders from the Online Mendelian Inheritance in OMIM database.
- CTD Chemicals (CC) Ontology CC is chemical vocabulary that is adapted by CTD from the "Chemicals and Drugs" category and Supplementary Concept Records of Medical Subject Headings (MeSH, a hierarchical vocabulary used to index articles for MEDLINE/PubMed).
Jump to [ Top · Hierarchy · Annotations ]
Root: CC Hierarchy (CTD chemicals from Comparative Toxicogenomics Database)
Jump to [ Top · Hierarchy ]
Superfamily( show details)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| DEK C-terminal domain | 0 | DIRECT |
| BAG domain | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| Mediator hinge subcomplex-like | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| Di-copper centre-containing domain | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| Nitric oxide (NO) synthase oxygenase domain | 0 | DIRECT |
| PAH2 domain | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Trimeric LpxA-like enzymes | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| Nucleoplasmin-like core domain | 0 | DIRECT |
| P-domain of calnexin/calreticulin | 0 | DIRECT |
| AhpD-like | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Indolic compounds 2,3-dioxygenase-like | 0 | DIRECT |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| Uracil-DNA glycosylase-like | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Stathmin | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| Release factor | 0 | DIRECT |
| FMT C-terminal domain-like | 0 | DIRECT |
| Alanine racemase C-terminal domain-like | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| ATP-dependent DNA ligase DNA-binding domain | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| Phosphofructokinase | 0 | DIRECT |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| Proteasome activator | 0 | DIRECT |
| 4Fe-4S ferredoxins | 0 | DIRECT |
| Fe-S cluster assembly (FSCA) domain-like | 0 | DIRECT |
| A heparin-binding domain | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| PWI domain | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| GFP-like | 0 | DIRECT |
| RGC domain-like | 0 | DIRECT |
| DLC | 0 | DIRECT |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | DIRECT |
| STAT | 0 | DIRECT |
| Connexin43 | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| C-terminal domain of PLC-beta | 0 | DIRECT |
| LuxS/MPP-like metallohydrolase | 0 | DIRECT |
| Ribosomal protein L16p/L10e | 0 | DIRECT |
| Transcription factor STAT-4 N-domain | 0 | DIRECT |
| beta-beta-alpha zinc fingers | 0.000002396 | DIRECT |
| Nucleic acid-binding proteins | 0.00003393 | DIRECT |
| SCOP hierarchy in SUPERFAMILY | 0.00006572 | DIRECT |
| Class II aaRS and biotin synthetases | 0.0002702 | DIRECT |
| Bromodomain | 0.0002986 | DIRECT |
| Protein kinase-like (PK-like) | 0.0008678 | DIRECT |
| HMG-box | 0.001478 | INHERITED FROM: Ascorbic Acid || Glycosides || beta-glycerophosphoric acid |
| Nuclear receptor ligand-binding domain | 0.001748 | INHERITED FROM: Saponins || Epirubicin || Hexoses || Oligosaccharides || pirarubicin || Glucosides || iron(II)-ascorbic acid complex || Sugars || Cardiac Glycosides || Trifluridine || Teniposide || Digitoxin || Digitalis Glycosides || Idarubicin || Cardenolides |
| Leucine zipper domain | 0.004134 | INHERITED FROM: Glucose || Sugar Alcohols || Monosaccharides || Amino Sugars || Hexoses || MLN7243 || Sugar Phosphates || Sugars || Glycerophosphates || Pyrimidine Nucleosides || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine || Glucosamine |
| BRCT domain | 0.004397 | INHERITED FROM: Daunorubicin || Anthracyclines || MLN7243 || Etoposide || fludarabine |
| KRAB domain (Kruppel-associated box) | 0.005308 | INHERITED FROM: MLN7243 || Glycosides || Nucleosides |
| Cyclin-like | 0.005372 | INHERITED FROM: Deoxyribonucleosides || allose || Deoxycytidine || acteoside || Thymidine || Zidovudine || Zalcitabine || fludarabine || Lamivudine || Cardenolides |
| Interleukin 8-like chemokines | 0.006086 | INHERITED FROM: Polysaccharides, Bacterial || Lanatosides || Glycerophospholipids || Amino Sugars || Deoxycytidine || Puromycin || acteoside || Lipopolysaccharides || beta-Glucans || Proscillaridin || Zymosan || peracetylated N-azidoacetylmannosamine || lipopolysaccharide, Helicobacter pylori || Digoxin || Chondroitin Sulfates || lipopolysaccharide, E. coli O26-B6 || gemcitabine || Digitoxigenin || Strophanthins || Digitoxin || Hesperidin || Polysaccharides || Glycoconjugates || polydatin || Digitalis Glycosides || Bufanolides |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.01023 | INHERITED FROM: Saponins || Epirubicin || Oligosaccharides || pirarubicin || Glucosides || Sugars || Trifluridine || Aclarubicin || Teniposide || Digitalis Glycosides || Idarubicin || Cardenolides |
| DNA/RNA polymerases | 0.0132 | INHERITED FROM: N6-(2-hydroxy-3-buten-1-yl)-2'-deoxyadenosine || 2'-deoxyadenosine || Deoxyadenosines |
| A DNA-binding domain in eukaryotic transcription factors | 0.0132 | INHERITED FROM: Sugar Acids || Ascorbic Acid || S-Adenosylmethionine |
| Growth factor receptor domain | 0.01366 | INHERITED FROM: secoisolariciresinol diglucoside |
| DNA-binding domain | 0.0151 | INHERITED FROM: Decitabine || pyrimidin-2-one beta-ribofuranoside || Azacitidine |
| Cysteine-rich domain | 0.01845 | INHERITED FROM: Dietary Carbohydrates |
| Caspase-like | 0.01962 | INHERITED FROM: Polysaccharides, Bacterial || WP 631 || Sugar Acids || Deoxyribonucleosides || Glucose || Uridine || Sugar Alcohols || Saponins || Monosaccharides || ginsenoside Rk1 || cyanidin 3-O-glucoside || Ceramides || methyl protodioscin || 28-O-acetylbetulin-3-ylglucopyranoside || Epirubicin || Hyaluronic Acid || paederosidic acid || Purine Nucleosides || Glycolipids || Hexoses || 2-Chloroadenosine || codonoposide || cinobufotalin || Adenosine || Ascorbic Acid || Lipopolysaccharides || 5-phenylselenylmethyl-2'-deoxyuridine || Sugar Phosphates || indioside D || ginsenoside Rg3 || Phosphatidylcholines || Meglumine || pyrimidin-2-one beta-ribofuranoside || Glucosides || Cardiac Glycosides || Trifluridine || Ribavirin || Glycosphingolipids || Hexosamines || Bleomycin || Deoxyadenosines || 5-methylselenylmethyl-2'-deoxyuridine || Gentamicins || Digitoxin || Pyrimidine Nucleosides || Glycopeptides || Neutral Glycosphingolipids || Vidarabine || Anthocyanins || Polysaccharides || dihydroceramide || Phosphatidic Acids || fludarabine || Glycoconjugates || obacunone glucoside || Bufanolides || Cladribine || Clofarabine |
| SMAD/FHA domain | 0.02249 | INHERITED FROM: aucubin || Iridoid Glucosides || Glucosides || Iridoid Glycosides || Vidarabine || fludarabine |
| Tudor/PWWP/MBT | 0.02339 | INHERITED FROM: MLN7243 |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.02352 | INHERITED FROM: Polysaccharides, Bacterial || Sugar Alcohols |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0.02352 | INHERITED FROM: Polysaccharides, Bacterial || Sugar Alcohols |
| FYVE/PHD zinc finger | 0.02744 | INHERITED FROM: MLN7243 || beta-glycerophosphoric acid |
| Complement control module/SCR domain | 0.02897 | INHERITED FROM: Platelet Activating Factor || Glyceryl Ethers || Phospholipid Ethers |
| Integrin domains | 0.03043 | INHERITED FROM: Saponins || ginsenoside M1 || peracetylated N-azidoacetylmannosamine || ginsenoside Rh1 |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.03543 | INHERITED FROM: Azacitidine || Pyrimidine Nucleosides || Nucleosides |
| Retrovirus capsid dimerization domain-like | 0.03593 | INHERITED FROM: MLN7243 |
| HSP40/DnaJ peptide-binding domain | 0.03626 | INHERITED FROM: Sugar Alcohols || Glycerophospholipids || Sugar Phosphates || Phosphatidylcholines || Triose Sugar Alcohols || Glycerophosphates || Phosphatidic Acids || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine |
| TIMP-like | 0.04105 | INHERITED FROM: Chondroitin || Chondroitin Sulfates || lipopolysaccharide, E. coli O26-B6 |
| FAD/NAD(P)-binding domain | 0.04432 | INHERITED FROM: Purine Nucleosides |
| DEATH domain | 0.05124 | INHERITED FROM: Deoxyribonucleosides || Glucose || Uridine || Sugar Alcohols || Saponins || Amino Sugars || Deoxycytidine || Purine Nucleosides || cinobufotalin || Adenosine || Lipopolysaccharides || 5-phenylselenylmethyl-2'-deoxyuridine || Sugar Phosphates || indioside D || Phosphatidylcholines || lipopolysaccharide, E. coli O26-B6 || Aclarubicin || Glycerophosphates || 5-methylselenylmethyl-2'-deoxyuridine || Digitoxin || Vidarabine || Polysaccharides || fludarabine || Glycoconjugates || Cladribine |
| Tubulin C-terminal domain-like | 0.0549 | INHERITED FROM: Pyrimidine Nucleosides |
| Toll/Interleukin receptor TIR domain | 0.05965 | INHERITED FROM: Lipopolysaccharides || lipopolysaccharide, E. coli O26-B6 || Polysaccharides || Glycoconjugates |
| Metallothionein | 0.06061 | INHERITED FROM: Decitabine || Bleomycin || Glycopeptides || bleomycetin || Glycoconjugates |
| DHS-like NAD/FAD-binding domain | 0.06061 | INHERITED FROM: Glucose || Monosaccharides || Hexoses |
| FnI-like domain | 0.06534 | INHERITED FROM: Glucose || Monosaccharides || Amino Sugars || ascorbate-2-phosphate || Hexoses || Ascorbic Acid || Sugar Phosphates || Hexosamines || Triose Sugar Alcohols || Glycerophosphates || Phosphatidic Acids |
| ARID-like | 0.07715 | INHERITED FROM: MLN7243 |
| SET domain | 0.08279 | INHERITED FROM: beta-glycerophosphoric acid |
| Ferritin-like | 0.0841 | INHERITED FROM: Tunicamycin |
| S15/NS1 RNA-binding domain | 0.0841 | INHERITED FROM: Sugar Acids || Deoxycytidine || Ascorbic Acid || Thymidine || Zidovudine || Tunicamycin || Zalcitabine || Dideoxynucleosides || Lamivudine |
| Cation efflux protein transmembrane domain-like | 0.08648 | INHERITED FROM: Deoxyribonucleosides || Thymidine || Zidovudine || Dideoxynucleosides |
| Single hybrid motif | 0.08648 | INHERITED FROM: Monosaccharides || Hexoses |
| PH domain-like | 0.09529 | INHERITED FROM: Daunorubicin || Aminoglycosides |
| SAP domain | 0.0999 | INHERITED FROM: MLN7243 |
| RNA-binding domain, RBD | 0.1022 | INHERITED FROM: MLN7243 |
| ABC transporter transmembrane region | 0.1027 | INHERITED FROM: Sugar Acids || Deoxyribonucleosides || Glucuronates || Saponins || Epirubicin || Ginsenosides || hesperetin || Thymidine || notoginsenoside R1 || Zidovudine || antibiotic G 418 || Gentamicins || Uronic Acids || Hesperidin |
| GroEL equatorial domain-like | 0.105 | INHERITED FROM: Glycerophospholipids || Sugar Phosphates || Phosphatidylcholines || Triose Sugar Alcohols || Glycerophosphates || Phosphatidic Acids || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine |
| Bcl-2 inhibitors of programmed cell death | 0.105 | INHERITED FROM: Polysaccharides, Bacterial || Sugar Acids || Sugar Alcohols || Saponins || ziyuglycoside II || Amino Sugars || platycodin D || paederosidic acid || Purine Nucleosides || delphinidin || Puromycin || Adenosine || Ascorbic Acid || Sugar Phosphates || indioside D || Meglumine || Plicamycin || Glucosides || Cardiac Glycosides || Hexosamines || Glycerophosphates || Deoxyadenosines || Etoposide || chan su || cordycepin || gemcitabine || Vidarabine || Anthocyanins || Deoxyglucose || Deoxy Sugars || Phosphatidic Acids || fludarabine || Bufanolides || Arabinonucleosides || N-(2-hydroxypropyl)methacrylamide co-polymer-doxorubicin conjugate |
| NAD(P)-linked oxidoreductase | 0.1165 | INHERITED FROM: Sugar Acids || Glyceraldehyde || Thionucleosides || Azathioprine || Trioses || daunorubicinol |
| 2Fe-2S ferredoxin-like | 0.1258 | INHERITED FROM: Polysaccharides, Bacterial |
| Rudiment single hybrid motif | 0.1258 | INHERITED FROM: Monosaccharides || Hexoses || Sugars |
| Kringle-like | 0.129 | INHERITED FROM: Sugar Acids || Sugar Alcohols || Saponins || Ascorbic Acid || Ouabain || Sugar Phosphates || Triose Sugar Alcohols || Glycerophosphates || Strophanthins || Polysaccharides || Phosphatidic Acids || Glycosaminoglycans |
| Nucleotidylyl transferase | 0.1294 | INHERITED FROM: Ascorbic Acid || Zalcitabine || Lamivudine |
| "Winged helix" DNA-binding domain | 0.1461 | INHERITED FROM: MLN7243 |
| SH2 domain | 0.1505 | INHERITED FROM: 6-hydroxy-3-O-methylkaempferol 6-O-glucopyranoside |
| Glutamine synthetase/guanido kinase | 0.1681 | INHERITED FROM: Etoposide |
| Nuclear receptor coactivator interlocking domain | 0.186 | INHERITED FROM: MLN7243 |
| GroEL-intermediate domain like | 0.1871 | INHERITED FROM: Sugar Alcohols || Glycerophospholipids || Sugar Phosphates || Phosphatidylcholines || Triose Sugar Alcohols || Glycerophosphates || Phosphatidic Acids || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine |
| Thioredoxin-like | 0.2127 | INHERITED FROM: 6-O-palmitoylascorbic acid || Streptozocin || Glucosamine |
| Fibronectin type III | 0.2128 | INHERITED FROM: Ribonucleosides || Cytidine |
| EGF/Laminin | 0.2173 | INHERITED FROM: Platelet Activating Factor || peracetylated N-azidoacetylmannosamine || Cytidine |
| MHC antigen-recognition domain | 0.2426 | INHERITED FROM: Glycerophospholipids || Lincosamides || Vancomycin || Phosphatidylcholines || Glycopeptides || Dideoxynucleosides || Phosphatidic Acids || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine |
| Carbonic anhydrase | 0.2482 | INHERITED FROM: Monosaccharides || Hexoses || 4-(4-((glucopyranosyl)thiomethyl)-5-iodo-1-H-1,2,3-triazol-1-yl)benzenesulfonamide || Ketoses || Sugars || Topiramate || 4-(4-((2',3',4',6'-tetra-O-acetylglucopyranosyl)thiomethyl)-5-iodo-1-H-1,2,3-triazol-1-yl)benzenesul || Fructose |
| GroEL apical domain-like | 0.2489 | INHERITED FROM: Sugar Alcohols || Glycerophospholipids || Sugar Phosphates || Phosphatidylcholines || Triose Sugar Alcohols || Glycerophosphates || Phosphatidic Acids || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine |
| Translation proteins SH3-like domain | 0.2489 | INHERITED FROM: MLN7243 |
| Mitochondrial carrier | 0.2548 | INHERITED FROM: Deoxyribonucleosides || Thymidine || Tunicamycin |
| Alkaline phosphatase-like | 0.261 | INHERITED FROM: Triose Sugar Alcohols || Glycerophosphates |
| GINS helical bundle-like | 0.2713 | INHERITED FROM: Thionucleosides || Azathioprine |
| PurM N-terminal domain-like | 0.2713 | INHERITED FROM: Decitabine |
| PurM C-terminal domain-like | 0.2713 | INHERITED FROM: Decitabine |
| GST C-terminal domain-like | 0.2714 | INHERITED FROM: Glucosamine |
| Serpins | 0.2821 | INHERITED FROM: periodate-oxidized adenosine || Polysaccharides |
| Cytokine | 0.2933 | INHERITED FROM: Lipopolysaccharides || Chondroitin Sulfates || Thioglycosides || Polysaccharides || Glycoconjugates || Glycosaminoglycans |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0.3073 | INHERITED FROM: Purine Nucleosides |
| Proton glutamate symport protein | 0.3073 | INHERITED FROM: Thymidine || Zidovudine || Dideoxynucleosides |
| Heme-dependent peroxidases | 0.3148 | INHERITED FROM: Glycerophospholipids || Sugar Phosphates || Triose Sugar Alcohols || Glycerophosphates || Phosphatidic Acids |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0.3254 | INHERITED FROM: Glycerophospholipids || Phosphatidylcholines || Heparin || Phosphatidic Acids || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine |
| TNF receptor-like | 0.3305 | INHERITED FROM: Amino Sugars || Lipopolysaccharides || gemcitabine || Vidarabine || Polysaccharides || fludarabine || Glycoconjugates |
| vWA-like | 0.3623 | INHERITED FROM: ginsenoside M1 || ginsenoside Rh1 |
| Cystine-knot cytokines | 0.371 | INHERITED FROM: delphinidin || cyanidin || Lipopolysaccharides || Plicamycin || Cardiac Glycosides || Chondroitin Sulfates || Digoxigenin || Strophanthins || Anthocyanins || Polysaccharides || Glycoconjugates || Cardenolides |
| TB module/8-cys domain | 0.3976 | INHERITED FROM: MLN7243 |
| PYP-like sensor domain (PAS domain) | 0.4212 | INHERITED FROM: 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || Digoxin || Anthocyanins || Digitalis Glycosides |
| Glutathione synthetase ATP-binding domain-like | 0.4212 | INHERITED FROM: Monosaccharides || Hexoses |
| p53-like transcription factors | 0.4401 | INHERITED FROM: Sugar Acids || Saponins || Amino Sugars || Ceramides || Glycolipids || Ascorbic Acid || Lipopolysaccharides || fucoidan || WP 744 || Glycosphingolipids || Hexosamines || 6-hydroxy-3-O-methylkaempferol 6-O-glucopyranoside || Thioglycosides || Gentamicins || Neutral Glycosphingolipids || Anthocyanins || Polysaccharides || Deoxy Sugars || Glycoconjugates |
| GLA-domain | 0.4447 | INHERITED FROM: Heparin |
| MFS general substrate transporter | 0.4475 | INHERITED FROM: Deoxyribonucleosides || 7-(deoxyadenosin-N(6)-yl)aristolactam I || 7-(deoxyguanosin-N(2)-yl)aristolactam I || Ketoses || Thymidine || Dehydroascorbic Acid || Dideoxynucleosides || Fructose |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.4701 | INHERITED FROM: Polysaccharides, Bacterial || Glucose || Sugar Alcohols || Glycerol || Hexoses || N-(4-O-glycerol-3-methoxybenzyl)nonivamide || Lipopolysaccharides || Sugars || Polysaccharides || Glycoconjugates |
| Riboflavin synthase domain-like | 0.4701 | INHERITED FROM: Polysaccharides, Bacterial || Glucose || Sugar Alcohols || Glycerol || Hexoses || N-(4-O-glycerol-3-methoxybenzyl)nonivamide || Lipopolysaccharides || Sugars || Polysaccharides || Glycoconjugates |
| PGBD-like | 0.4701 | INHERITED FROM: Sugar Acids || Glucose || Saponins || Monosaccharides || Amino Sugars || Deoxycytidine || Hexoses || Ascorbic Acid || Ouabain || Lipopolysaccharides || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || fucoidan || Sugars || Cardiac Glycosides || Hexosamines || bufalin || Polysaccharides || Streptozocin || Glycoconjugates || Glucosamine |
| FAD-linked reductases, C-terminal domain | 0.4701 | INHERITED FROM: periodate-oxidized adenosine |
| EF-hand | 0.5068 | INHERITED FROM: 1-Deoxynojirimycin || miglitol || Imino Pyranoses || Imino Sugars |
| Hemopexin-like domain | 0.5489 | INHERITED FROM: Glucose || Saponins || Amino Sugars || Purine Nucleosides || Ouabain || Lipopolysaccharides || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || fucoidan || Cardiac Glycosides || Hexosamines || bufalin || Polysaccharides || Streptozocin || Glycoconjugates || Glucosamine |
| Flavoproteins | 0.5598 | INHERITED FROM: Polysaccharides, Bacterial || Sugar Acids || Glucose || Sugar Alcohols || Saponins || Monosaccharides || Hexoses || Ascorbic Acid || Lipopolysaccharides || Sugars || Anthocyanins || Polysaccharides || Glycoconjugates |
| TNF-like | 0.5604 | INHERITED FROM: Amino Sugars || Lipopolysaccharides || Plicamycin || Hexosamines || Polysaccharides || Glycoconjugates |
| Metalloproteases ("zincins"), catalytic domain | 0.5671 | INHERITED FROM: Amino Sugars || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || fucoidan || Hexosamines || Streptozocin || Glucosamine |
| PreATP-grasp domain | 0.6128 | INHERITED FROM: Monosaccharides || Hexoses || Sugars |
| Chaperone J-domain | 0.6283 | INHERITED FROM: Sugar Alcohols || Glycerophospholipids || Sugar Phosphates || Phosphatidylcholines || Triose Sugar Alcohols || Glycerophosphates || Phosphatidic Acids || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine |
| Arginase/deacetylase | 0.6559 | INHERITED FROM: Saponins || Ginsenosides || ginsenoside Rh2 |
| Cytochrome P450 | 0.663 | INHERITED FROM: Mannitol || Sugar Alcohols || Purine Nucleosides || stevioside || hesperetin || Guanosine || Dietary Carbohydrates || Oligosaccharides || Cyclodextrins || Starch || Celsior || Disaccharides || Sugars || Dextrins || tamarixetin || Hesperidin || Polysaccharides || Deoxyguanosine |
| GroES-like | 0.6827 | INHERITED FROM: Phosphatidylcholines |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.6859 | INHERITED FROM: S-Adenosylmethionine |
| SpoIIaa-like | 0.7032 | INHERITED FROM: Deoxyribonucleosides || Thymidine || Zidovudine || Dideoxynucleosides |
| 4-helical cytokines | 0.7279 | INHERITED FROM: Polysaccharides, Bacterial || Sugar Acids || Deoxyribonucleosides || Glucose || Sugar Alcohols || Amino Sugars || Deoxycytidine || Epirubicin || Ribonucleosides || lipopolysaccharide, E coli O55-B5 || Lipopolysaccharides || hesperetin || Sugar Phosphates || Gluconates || beta-Glucans || Thymidine || Zymosan || FEC protocol || Thionucleosides || Muramic Acids || Ribavirin || Azathioprine || gemcitabine || Glycopeptides || Antimony Sodium Gluconate || Hesperidin || Polysaccharides || Phosphatidic Acids || Glycoconjugates || Glucosamine || Acetylmuramyl-Alanyl-Isoglutamine || Teichoic Acids |
| SNF-like | 0.8118 | INHERITED FROM: Thymidine || Dideoxynucleosides |
| Calcium ATPase, transmembrane domain M | 0.8403 | INHERITED FROM: Ouabain || Strophanthins || Cardenolides |
| E set domains | 0.8673 | INHERITED FROM: fucoidan |
| POZ domain | 0.8713 | INHERITED FROM: MLN7243 |
| LDH C-terminal domain-like | 0.8763 | INHERITED FROM: Glucose || Monosaccharides || Hexoses || Sugars |
| Calcium ATPase, transduction domain A | 0.88 | INHERITED FROM: Ouabain || Strophanthins || Cardenolides |
| HLH, helix-loop-helix DNA-binding domain | 0.9397 | INHERITED FROM: Anthocyanins |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0.94 | INHERITED FROM: Glyceryl Ethers || Phospholipid Ethers |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.9489 | INHERITED FROM: Ouabain || Strophanthins || Cardenolides |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.9535 | INHERITED FROM: Sugar Acids || Glucuronates || 4-((methylnitrosoamino)-1-(3-pyridyl)but-1-yl)beta-omega-glucosiduronic acid || Uronic Acids |
| Cysteine proteinases | 0.9617 | INHERITED FROM: Chondroitin || Chondroitin Sulfates |
| Aquaporin-like | 0.9625 | INHERITED FROM: Glycerol |
| C-type lectin-like | 1 | INHERITED FROM: Glycerophospholipids || Platelet Activating Factor || Glyceryl Ethers || Polysaccharides |
| L domain-like | 1 | INHERITED FROM: secoisolariciresinol diglucoside || phosphatidylinositol 3,4,5-triphosphate |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: oleandrin |
| RNI-like | 1 | INHERITED FROM: Muramic Acids || Acetylmuramyl-Alanyl-Isoglutamine |
| Immunoglobulin | 1 | INHERITED FROM: Lincosamides || glucuronoxylomannan |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| DEK C-terminal domain | 0 | Direct |
| BAG domain | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| Mediator hinge subcomplex-like | 0 | Direct |
| SIS domain | 0 | Direct |
| Di-copper centre-containing domain | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| Nitric oxide (NO) synthase oxygenase domain | 0 | Direct |
| PAH2 domain | 0 | Direct |
| FF domain | 0 | Direct |
| Trimeric LpxA-like enzymes | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| Nucleoplasmin-like core domain | 0 | Direct |
| P-domain of calnexin/calreticulin | 0 | Direct |
| AhpD-like | 0 | Direct |
| BRK domain-like | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Indolic compounds 2,3-dioxygenase-like | 0 | Direct |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| Uracil-DNA glycosylase-like | 0 | Direct |
| Nop domain | 0 | Direct |
| Stathmin | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| Release factor | 0 | Direct |
| FMT C-terminal domain-like | 0 | Direct |
| Alanine racemase C-terminal domain-like | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| ATP-dependent DNA ligase DNA-binding domain | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| Phosphofructokinase | 0 | Direct |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| Proteasome activator | 0 | Direct |
| 4Fe-4S ferredoxins | 0 | Direct |
| Fe-S cluster assembly (FSCA) domain-like | 0 | Direct |
| A heparin-binding domain | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| PWI domain | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| GFP-like | 0 | Direct |
| RGC domain-like | 0 | Direct |
| DLC | 0 | Direct |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | Direct |
| STAT | 0 | Direct |
| Connexin43 | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Ribosomal protein S18 | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| C-terminal domain of PLC-beta | 0 | Direct |
| LuxS/MPP-like metallohydrolase | 0 | Direct |
| Ribosomal protein L16p/L10e | 0 | Direct |
| Transcription factor STAT-4 N-domain | 0 | Direct |
| beta-beta-alpha zinc fingers | 0.000002396 | Direct |
| Nucleic acid-binding proteins | 0.00003393 | Direct |
| SCOP hierarchy in SUPERFAMILY | 0.00006572 | Direct |
| Class II aaRS and biotin synthetases | 0.0002702 | Direct |
| Bromodomain | 0.0002986 | Direct |
| Protein kinase-like (PK-like) | 0.0008678 | Direct |
| HMG-box | 0.001478 | Inherited |
| Nuclear receptor ligand-binding domain | 0.001748 | Inherited |
| Leucine zipper domain | 0.004134 | Inherited |
| BRCT domain | 0.004397 | Inherited |
| KRAB domain (Kruppel-associated box) | 0.005308 | Inherited |
| Cyclin-like | 0.005372 | Inherited |
| Interleukin 8-like chemokines | 0.006086 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.01023 | Inherited |
| DNA/RNA polymerases | 0.0132 | Inherited |
| A DNA-binding domain in eukaryotic transcription factors | 0.0132 | Inherited |
| Growth factor receptor domain | 0.01366 | Inherited |
| DNA-binding domain | 0.0151 | Inherited |
| Cysteine-rich domain | 0.01845 | Inherited |
| Caspase-like | 0.01962 | Inherited |
| SMAD/FHA domain | 0.02249 | Inherited |
| Tudor/PWWP/MBT | 0.02339 | Inherited |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.02352 | Inherited |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0.02352 | Inherited |
| FYVE/PHD zinc finger | 0.02744 | Inherited |
| Complement control module/SCR domain | 0.02897 | Inherited |
| Integrin domains | 0.03043 | Inherited |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.03543 | Inherited |
| Retrovirus capsid dimerization domain-like | 0.03593 | Inherited |
| HSP40/DnaJ peptide-binding domain | 0.03626 | Inherited |
| TIMP-like | 0.04105 | Inherited |
| FAD/NAD(P)-binding domain | 0.04432 | Inherited |
| DEATH domain | 0.05124 | Inherited |
| Tubulin C-terminal domain-like | 0.0549 | Inherited |
| Toll/Interleukin receptor TIR domain | 0.05965 | Inherited |
| Metallothionein | 0.06061 | Inherited |
| DHS-like NAD/FAD-binding domain | 0.06061 | Inherited |
| FnI-like domain | 0.06534 | Inherited |
| ARID-like | 0.07715 | Inherited |
| SET domain | 0.08279 | Inherited |
| Ferritin-like | 0.0841 | Inherited |
| S15/NS1 RNA-binding domain | 0.0841 | Inherited |
| Cation efflux protein transmembrane domain-like | 0.08648 | Inherited |
| Single hybrid motif | 0.08648 | Inherited |
| PH domain-like | 0.09529 | Inherited |
| SAP domain | 0.0999 | Inherited |
| RNA-binding domain, RBD | 0.1022 | Inherited |
| ABC transporter transmembrane region | 0.1027 | Inherited |
| GroEL equatorial domain-like | 0.105 | Inherited |
| Bcl-2 inhibitors of programmed cell death | 0.105 | Inherited |
| NAD(P)-linked oxidoreductase | 0.1165 | Inherited |
| 2Fe-2S ferredoxin-like | 0.1258 | Inherited |
| Rudiment single hybrid motif | 0.1258 | Inherited |
| Kringle-like | 0.129 | Inherited |
| Nucleotidylyl transferase | 0.1294 | Inherited |
| "Winged helix" DNA-binding domain | 0.1461 | Inherited |
| SH2 domain | 0.1505 | Inherited |
| Glutamine synthetase/guanido kinase | 0.1681 | Inherited |
| Nuclear receptor coactivator interlocking domain | 0.186 | Inherited |
| GroEL-intermediate domain like | 0.1871 | Inherited |
| Thioredoxin-like | 0.2127 | Inherited |
| Fibronectin type III | 0.2128 | Inherited |
| EGF/Laminin | 0.2173 | Inherited |
| MHC antigen-recognition domain | 0.2426 | Inherited |
| Carbonic anhydrase | 0.2482 | Inherited |
| GroEL apical domain-like | 0.2489 | Inherited |
| Translation proteins SH3-like domain | 0.2489 | Inherited |
| Mitochondrial carrier | 0.2548 | Inherited |
| Alkaline phosphatase-like | 0.261 | Inherited |
| GINS helical bundle-like | 0.2713 | Inherited |
| PurM N-terminal domain-like | 0.2713 | Inherited |
| PurM C-terminal domain-like | 0.2713 | Inherited |
| GST C-terminal domain-like | 0.2714 | Inherited |
| Serpins | 0.2821 | Inherited |
| Cytokine | 0.2933 | Inherited |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0.3073 | Inherited |
| Proton glutamate symport protein | 0.3073 | Inherited |
| Heme-dependent peroxidases | 0.3148 | Inherited |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0.3254 | Inherited |
| TNF receptor-like | 0.3305 | Inherited |
| vWA-like | 0.3623 | Inherited |
| Cystine-knot cytokines | 0.371 | Inherited |
| TB module/8-cys domain | 0.3976 | Inherited |
| PYP-like sensor domain (PAS domain) | 0.4212 | Inherited |
| Glutathione synthetase ATP-binding domain-like | 0.4212 | Inherited |
| p53-like transcription factors | 0.4401 | Inherited |
| GLA-domain | 0.4447 | Inherited |
| MFS general substrate transporter | 0.4475 | Inherited |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.4701 | Inherited |
| Riboflavin synthase domain-like | 0.4701 | Inherited |
| PGBD-like | 0.4701 | Inherited |
| FAD-linked reductases, C-terminal domain | 0.4701 | Inherited |
| EF-hand | 0.5068 | Inherited |
| Hemopexin-like domain | 0.5489 | Inherited |
| Flavoproteins | 0.5598 | Inherited |
| TNF-like | 0.5604 | Inherited |
| Metalloproteases ("zincins"), catalytic domain | 0.5671 | Inherited |
| PreATP-grasp domain | 0.6128 | Inherited |
| Chaperone J-domain | 0.6283 | Inherited |
| Arginase/deacetylase | 0.6559 | Inherited |
| Cytochrome P450 | 0.663 | Inherited |
| GroES-like | 0.6827 | Inherited |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.6859 | Inherited |
| SpoIIaa-like | 0.7032 | Inherited |
| 4-helical cytokines | 0.7279 | Inherited |
| SNF-like | 0.8118 | Inherited |
| Calcium ATPase, transmembrane domain M | 0.8403 | Inherited |
| E set domains | 0.8673 | Inherited |
| POZ domain | 0.8713 | Inherited |
| LDH C-terminal domain-like | 0.8763 | Inherited |
| Calcium ATPase, transduction domain A | 0.88 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.9397 | Inherited |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0.94 | Inherited |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.9489 | Inherited |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.9535 | Inherited |
| Cysteine proteinases | 0.9617 | Inherited |
| Aquaporin-like | 0.9625 | Inherited |
| C-type lectin-like | 1 | Inherited |
| L domain-like | 1 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
| RNI-like | 1 | Inherited |
| Immunoglobulin | 1 | Inherited |
LINKTO: Domain2BO Download and Domain2BO Algorithm
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Family( show details)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| RWD domain | 0 | DIRECT |
| Stathmin | 0 | DIRECT |
| Connexin43 | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| C5 cytosine-specific DNA methylase, DCM | 0 | DIRECT |
| PreBEACH PH-like domain | 0 | DIRECT |
| Release factor | 0 | DIRECT |
| TRASH domain | 0 | DIRECT |
| Alkaline phosphatase | 0 | DIRECT |
| eIF5a N-terminal domain-like | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| 2'-5'-oligoadenylate synthetase 1, OAS1, second domain | 0 | DIRECT |
| Serine carboxypeptidase-like | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| RNB domain-like | 0 | DIRECT |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | DIRECT |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| DNA ligase | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| Methyl-CpG-binding domain, MBD | 0 | DIRECT |
| DEATH effector domain, DED | 0 | DIRECT |
| PWI domain | 0 | DIRECT |
| S-adenosylhomocystein hydrolase | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | DIRECT |
| Phosphofructokinase | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| DLC | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | DIRECT |
| P-domain of calnexin/calreticulin | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| E2F dimerization segment | 0 | DIRECT |
| 2'-5'-oligoadenylate synthetase 1, OAS1, N-terminal domain | 0 | DIRECT |
| STAT | 0 | DIRECT |
| TatD Mg-dependent DNase-like | 0 | DIRECT |
| DEK C-terminal domain | 0 | DIRECT |
| Pseudouridine synthase RsuA/RluD | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| a tRNA synthase domain | 0 | DIRECT |
| Interferon regulatory factor 3 (IRF3), transactivation domain | 0 | DIRECT |
| Tetrahydrofolate dehydrogenase/cyclohydrolase | 0 | DIRECT |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
| NOL1/NOP2/sun | 0 | DIRECT |
| Proteasome activator | 0 | DIRECT |
| Interferon regulatory factor | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, C-terminal domain | 0 | DIRECT |
| ATP-dependent DNA ligase catalytic domain | 0 | DIRECT |
| Starch-binding domain | 0 | DIRECT |
| Transcription factor STAT-4 N-domain | 0 | DIRECT |
| SPOC domain | 0 | DIRECT |
| Transferrin | 0 | DIRECT |
| MIF4G domain-like | 0 | DIRECT |
| AAT-like | 0 | DIRECT |
| DNA/RNA non-specific endonuclease | 0 | DIRECT |
| Troponin I | 0 | DIRECT |
| Phoshatidylinositol transfer protein, PITP | 0 | DIRECT |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| Anticodon-binding domain | 0 | DIRECT |
| Eukaryotic ODC-like | 0 | DIRECT |
| B56-like | 0 | DIRECT |
| Cystathionine synthase-like | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| CPH domain | 0 | DIRECT |
| Protein prenyltransferases | 0 | DIRECT |
| Retinoblastoma tumor suppressor domains | 0 | DIRECT |
| MPP-like | 0 | DIRECT |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | DIRECT |
| Phosphoribulokinase/pantothenate kinase | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| 5' to 3' exonuclease catalytic domain | 0 | DIRECT |
| Oligosaccharide phosphorylase | 0 | DIRECT |
| Alanine racemase-like, N-terminal domain | 0 | DIRECT |
| Nitric oxide (NO) synthase oxygenase domain | 0 | DIRECT |
| DNA polymerase beta-like | 0 | DIRECT |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | DIRECT |
| Pseudouridine synthase II TruB | 0 | DIRECT |
| Calnexin/calreticulin | 0 | DIRECT |
| GHMP Kinase, N-terminal domain | 0 | DIRECT |
| Ccg1/TafII250-interacting factor B (Cib) | 0 | DIRECT |
| AlaX-M N-terminal domain-like | 0 | DIRECT |
| Cytidylyltransferase | 0 | DIRECT |
| beta-glycanases | 0 | DIRECT |
| Variant SAM domain | 0 | DIRECT |
| Hsp90 middle domain | 0 | DIRECT |
| Phosphoribosyltransferases (PRTases) | 0 | DIRECT |
| Nucleoplasmin-like core domain | 0 | DIRECT |
| Neurotrophin | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Domain G2 of nidogen-1 | 0 | DIRECT |
| Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
| Ferredoxin domains from multidomain proteins | 0 | DIRECT |
| Tissue inhibitor of metalloproteinases, TIMP | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| DNA polymerase I | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| A heparin-binding domain | 0 | DIRECT |
| Variant RING domain | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| SMAD domain | 0 | DIRECT |
| RNA methyltransferase FtsJ | 0 | DIRECT |
| HD domain | 0 | DIRECT |
| STAT DNA-binding domain | 0 | DIRECT |
| C-terminal domain of PLC-beta | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme postcatalytic domain | 0 | DIRECT |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| BAG domain | 0 | DIRECT |
| RGC domain | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| PAH2 domain | 0 | DIRECT |
| Splicing factor U2AF subunits | 0 | DIRECT |
| Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain | 0 | DIRECT |
| Ecto-ART | 0 | DIRECT |
| Tandem AAA-ATPase domain | 0.00006098 | DIRECT |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0.0000788 | DIRECT |
| Classic zinc finger, C2H2 | 0.0001062 | DIRECT |
| Histone lysine methyltransferases | 0.0001286 | DIRECT |
| Bromodomain | 0.0003363 | DIRECT |
| PWWP domain | 0.0005522 | DIRECT |
| Nuclear receptor | 0.001197 | INHERITED FROM: Saponins || Epirubicin || Hexoses || Oligosaccharides || pirarubicin || Glucosides || iron(II)-ascorbic acid complex || Sugars || Cardiac Glycosides || Trifluridine || Teniposide || Digitoxin || Digitalis Glycosides || Idarubicin || Cardenolides |
| HMG-box | 0.001727 | INHERITED FROM: Ascorbic Acid || Glycosides || beta-glycerophosphoric acid |
| Nuclear receptor ligand-binding domain | 0.00201 | INHERITED FROM: Saponins || Epirubicin || Hexoses || Oligosaccharides || pirarubicin || Glucosides || iron(II)-ascorbic acid complex || Sugars || Cardiac Glycosides || Trifluridine || Teniposide || ginsenoside Re || Digitoxin || Digitalis Glycosides || Idarubicin || Cardenolides |
| DEATH domain, DD | 0.003178 | INHERITED FROM: Lipopolysaccharides || lipopolysaccharide, E. coli O26-B6 || gemcitabine || Polysaccharides || Glycoconjugates |
| Leucine zipper domain | 0.004763 | INHERITED FROM: Glucose || Sugar Alcohols || Monosaccharides || Amino Sugars || Hexoses || MLN7243 || Sugar Phosphates || Sugars || Glycerophosphates || Pyrimidine Nucleosides || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine || Glucosamine |
| Protein kinases, catalytic subunit | 0.006735 | INHERITED FROM: aucubin || beta-Cyclodextrins || Saponins || platycodin D || Tubercidin || Ascorbic Acid || Ouabain || quercetin 4'-O-glucopyranoside || didymin || N-acetylglucosaminono-1,5-lactone O-(phenylcarbamoyl)oxime || Cyclodextrins || Glucosides || Cardiac Glycosides || phosphoramidon || 5-iodotubercidin || Hexosamines || Iridoid Glycosides || Inositol Phosphates || Deoxy Sugars || liposomal doxorubicin |
| Interleukin 8-like chemokines | 0.006774 | INHERITED FROM: Polysaccharides, Bacterial || Lanatosides || Glycerophospholipids || Amino Sugars || Puromycin || acteoside || Lipopolysaccharides || beta-Glucans || Proscillaridin || Zymosan || peracetylated N-azidoacetylmannosamine || lipopolysaccharide, Helicobacter pylori || Digoxin || Chondroitin Sulfates || lipopolysaccharide, E. coli O26-B6 || gemcitabine || Digitoxigenin || Strophanthins || Digitoxin || Hesperidin || Polysaccharides || Glycoconjugates || polydatin || Digitalis Glycosides || Bufanolides |
| Cold shock DNA-binding domain-like | 0.009319 | INHERITED FROM: MLN7243 |
| Third domain of FERM | 0.009319 | INHERITED FROM: Doxorubicin || Daunorubicin || Anthracyclines |
| PHD domain | 0.01089 | INHERITED FROM: MLN7243 || beta-glycerophosphoric acid |
| A DNA-binding domain in eukaryotic transcription factors | 0.01296 | INHERITED FROM: Sugar Acids || Ascorbic Acid || S-Adenosylmethionine |
| Cell cycle transcription factor e2f-dp | 0.01441 | INHERITED FROM: Thionucleosides || Azathioprine |
| KRAB domain (Kruppel-associated box) | 0.01851 | INHERITED FROM: MLN7243 || Nucleosides |
| ABC transporter transmembrane region | 0.01873 | INHERITED FROM: Sugar Acids || Deoxyribonucleosides || Glucuronates || Saponins || Epirubicin || Daunorubicin || Anthracyclines || Ginsenosides || hesperetin || Thymidine || notoginsenoside R1 || Zidovudine || Etoposide || antibiotic G 418 || Gentamicins || Uronic Acids || Hesperidin |
| Cation efflux protein transmembrane domain-like | 0.0224 | INHERITED FROM: Deoxyribonucleosides || Thymidine || Zidovudine || Dideoxynucleosides |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.0224 | INHERITED FROM: Polysaccharides, Bacterial || Sugar Alcohols |
| Anticodon-binding domain of Class II aaRS | 0.0224 | INHERITED FROM: Ascorbic Acid |
| Interleukin-1 (IL-1) | 0.0224 | INHERITED FROM: Polysaccharides, Bacterial || Lipopolysaccharides || Polysaccharides || Glycoconjugates |
| Cyclin | 0.02667 | INHERITED FROM: allose || Deoxycytidine || acteoside || Thymidine || Zidovudine || Zalcitabine || fludarabine || Lamivudine || Cardenolides |
| Double-stranded RNA-binding domain (dsRBD) | 0.02821 | INHERITED FROM: MLN7243 |
| Integrin domains | 0.0312 | INHERITED FROM: Saponins || ginsenoside M1 || peracetylated N-azidoacetylmannosamine || ginsenoside Rh1 |
| Complement control module/SCR domain | 0.03265 | INHERITED FROM: Platelet Activating Factor || Glyceryl Ethers || Phospholipid Ethers |
| ABC transporter ATPase domain-like | 0.03296 | INHERITED FROM: Sugar Acids || Deoxyribonucleosides || Glucuronates || hesperetin || Thymidine || notoginsenoside R1 || Zidovudine || Dichlororibofuranosylbenzimidazole || antibiotic G 418 || Gentamicins || Dideoxynucleosides |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0.03445 | INHERITED FROM: Sugar Alcohols |
| HSP40/DnaJ peptide-binding domain | 0.03445 | INHERITED FROM: Sugar Alcohols || Glycerophospholipids || Sugar Phosphates || Phosphatidylcholines || Triose Sugar Alcohols || Glycerophosphates || Phosphatidic Acids || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine |
| SCAN domain | 0.04024 | INHERITED FROM: MLN7243 |
| Caspase catalytic domain | 0.041 | INHERITED FROM: Polysaccharides, Bacterial || WP 631 || Sugar Acids || Deoxyribonucleosides || Glucose || Uridine || Sugar Alcohols || Saponins || Monosaccharides || ginsenoside Rk1 || cyanidin 3-O-glucoside || Ceramides || methyl protodioscin || 28-O-acetylbetulin-3-ylglucopyranoside || Epirubicin || Hyaluronic Acid || paederosidic acid || Purine Nucleosides || Glycolipids || Hexoses || 2-Chloroadenosine || codonoposide || cinobufotalin || Adenosine || Ascorbic Acid || Lipopolysaccharides || 5-phenylselenylmethyl-2'-deoxyuridine || Sugar Phosphates || indioside D || ginsenoside Rg3 || Phosphatidylcholines || Meglumine || pyrimidin-2-one beta-ribofuranoside || Glucosides || Sugars || Cardiac Glycosides || Trifluridine || Ribavirin || Glycosphingolipids || Hexosamines || Bleomycin || Deoxyadenosines || 5-methylselenylmethyl-2'-deoxyuridine || Gentamicins || Digitoxin || Pyrimidine Nucleosides || Glycopeptides || Neutral Glycosphingolipids || Vidarabine || Anthocyanins || Polysaccharides || Phosphatidic Acids || fludarabine || Glycoconjugates || obacunone glucoside || Bufanolides || Cladribine || Clofarabine |
| Short-chain cytokines | 0.041 | INHERITED FROM: Polysaccharides, Bacterial || Deoxyribonucleosides || Deoxycytidine || Lipopolysaccharides || Ribavirin || gemcitabine || Polysaccharides || Glycoconjugates |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0.05265 | INHERITED FROM: Thionucleosides || Azathioprine || Etoposide |
| Tubulin, C-terminal domain | 0.05559 | INHERITED FROM: Pyrimidine Nucleosides |
| Metallothionein | 0.05874 | INHERITED FROM: Decitabine || Bleomycin || Glycopeptides || bleomycetin || Glycoconjugates |
| Proteasome subunits | 0.06545 | INHERITED FROM: Sugar Alcohols || Glycerophospholipids || Sugar Phosphates || Phosphatidylcholines || Triose Sugar Alcohols || Glycerophosphates || Heparin || Phosphatidic Acids || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine || Glycosaminoglycans |
| Caspase recruitment domain, CARD | 0.06545 | INHERITED FROM: Polysaccharides, Bacterial || Lipopolysaccharides || Phosphatidylcholines || Bufanolides |
| Hypoxia-inducible factor Hif2a, C-terminal domain | 0.07555 | INHERITED FROM: Anthocyanins |
| ARID domain | 0.07555 | INHERITED FROM: MLN7243 |
| Papain-like | 0.07555 | INHERITED FROM: Chondroitin || Chondroitin Sulfates || Glycosaminoglycans |
| L domain | 0.07937 | INHERITED FROM: Deoxyribonucleosides || secoisolariciresinol diglucoside || Glucose || Saponins || Monosaccharides || platycodin D || Epirubicin || Hexoses || Glucosides || Sugars || Etoposide || Deoxyglucose || Deoxy Sugars |
| Glutathione S-transferase (GST), C-terminal domain | 0.08259 | INHERITED FROM: Hexosamines || Glucosamine |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0.08314 | INHERITED FROM: Glycerophospholipids || Phosphatidylcholines || Triose Sugar Alcohols || Glycerophosphates || Phosphatidic Acids || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine |
| Biotinyl/lipoyl-carrier proteins and domains | 0.08314 | INHERITED FROM: Monosaccharides || Hexoses |
| Glutathione peroxidase-like | 0.08705 | INHERITED FROM: Hexosamines || Acetylglucosamine || Pyrimidine Nucleosides || Streptozocin || Glucosamine |
| TNF receptor-like | 0.09528 | INHERITED FROM: Amino Sugars || Lipopolysaccharides || gemcitabine || Vidarabine || Polysaccharides || fludarabine || Glycoconjugates |
| SAP domain | 0.1007 | INHERITED FROM: MLN7243 |
| Toll/Interleukin receptor TIR domain | 0.1007 | INHERITED FROM: Lipopolysaccharides || lipopolysaccharide, E. coli O26-B6 || Polysaccharides || Glycoconjugates |
| Bcl-2 inhibitors of programmed cell death | 0.1024 | INHERITED FROM: Polysaccharides, Bacterial || Sugar Acids || Sugar Alcohols || Saponins || ziyuglycoside II || Amino Sugars || platycodin D || paederosidic acid || Purine Nucleosides || delphinidin || Puromycin || Adenosine || Ascorbic Acid || Sugar Phosphates || indioside D || Meglumine || Plicamycin || Glucosides || Cardiac Glycosides || Hexosamines || Glycerophosphates || Deoxyadenosines || Etoposide || chan su || cordycepin || gemcitabine || Vidarabine || Anthocyanins || Deoxyglucose || Deoxy Sugars || Phosphatidic Acids || fludarabine || Bufanolides || Arabinonucleosides || N-(2-hydroxypropyl)methacrylamide co-polymer-doxorubicin conjugate |
| NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0.1024 | INHERITED FROM: Polysaccharides, Bacterial || Decitabine || Lipopolysaccharides || fucoidan || lipopolysaccharide, E. coli O26-B6 || gemcitabine || Polysaccharides || Glycoconjugates || Nucleosides |
| C1 set domains (antibody constant domain-like) | 0.1082 | INHERITED FROM: Lincosamides || Vancomycin || Phosphatidylcholines || Glycopeptides || Dideoxynucleosides || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine |
| S100 proteins | 0.1149 | INHERITED FROM: 1-Deoxynojirimycin || Decitabine || Ribonucleosides || miglitol || Imino Pyranoses || Imino Sugars || Azacitidine || Cytidine |
| Aldo-keto reductases (NADP) | 0.1149 | INHERITED FROM: Sugar Acids || Glyceraldehyde || Thionucleosides || Azathioprine || Trioses || daunorubicinol |
| Rel/Dorsal transcription factors, DNA-binding domain | 0.1166 | INHERITED FROM: Polysaccharides, Bacterial || Ascorbic Acid || Lipopolysaccharides || fucoidan || lipopolysaccharide, E. coli O26-B6 || gemcitabine || Glycopeptides || Polysaccharides || Glycoconjugates |
| NADPH-cytochrome p450 reductase FAD-binding domain-like | 0.1186 | INHERITED FROM: Polysaccharides, Bacterial || Glucose || Sugar Alcohols || Monosaccharides || Hexoses || Lipopolysaccharides || Sugars || Polysaccharides || Glycoconjugates |
| BC C-terminal domain-like | 0.1186 | INHERITED FROM: Monosaccharides || Hexoses || Sugars |
| DNA gyrase/MutL, N-terminal domain | 0.1186 | INHERITED FROM: Decitabine || Azacitidine |
| NADPH-cytochrome p450 reductase-like | 0.1186 | INHERITED FROM: Polysaccharides, Bacterial || Glucose || Sugar Alcohols || Monosaccharides || Hexoses || Lipopolysaccharides || Sugars || Polysaccharides || Glycoconjugates |
| GABARAP-like | 0.1186 | INHERITED FROM: Decitabine || Azacitidine |
| Interleukin 17F, IL-17F | 0.1186 | INHERITED FROM: Polysaccharides, Bacterial || Lipopolysaccharides |
| DNA gyrase/MutL, second domain | 0.1186 | INHERITED FROM: Decitabine || Azacitidine |
| Laminin-type module | 0.1227 | INHERITED FROM: lysophosphatidic acid || Triose Sugar Alcohols || Glycerophosphates || sphingosine 1-phosphate || Lysophosphatidylcholines || Phosphatidic Acids |
| Glutathione S-transferase (GST), N-terminal domain | 0.1275 | INHERITED FROM: Amino Sugars || Hexosamines || Glucosamine |
| BTB/POZ domain | 0.137 | INHERITED FROM: MLN7243 |
| PDI-like | 0.1374 | INHERITED FROM: Tunicamycin |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.1561 | INHERITED FROM: Polysaccharides, Bacterial || Deoxycytidine || Ascorbic Acid || Lipopolysaccharides || Zidovudine || Tunicamycin || Zalcitabine || Dideoxynucleosides || Lamivudine |
| EGF-type module | 0.1599 | INHERITED FROM: Platelet Activating Factor || Glyceryl Ethers || Phospholipid Ethers || Oligosaccharides |
| C2 set domains | 0.1609 | INHERITED FROM: Sugar Acids || Amino Sugars || Ribonucleosides || lipopolysaccharide, E coli O55-B5 || Dietary Carbohydrates |
| Myb/SANT domain | 0.1611 | INHERITED FROM: MLN7243 |
| SH2 domain | 0.1726 | INHERITED FROM: 6-hydroxy-3-O-methylkaempferol 6-O-glucopyranoside |
| Nuclear receptor coactivator interlocking domain | 0.1754 | INHERITED FROM: MLN7243 |
| Fibronectin type II module | 0.1816 | INHERITED FROM: Glucose || Saponins || Amino Sugars || Ouabain || Cardiac Glycosides || Hexosamines || Glycerophosphates || Strophanthins || Polysaccharides || Phosphatidic Acids || Glycoconjugates || Cardenolides |
| Transforming growth factor (TGF)-beta | 0.1855 | INHERITED FROM: Lipopolysaccharides || Polysaccharides || Glycoconjugates |
| Canonical RBD | 0.191 | INHERITED FROM: MLN7243 |
| VWC domain | 0.1963 | INHERITED FROM: Amino Sugars || Hexosamines |
| Mitochondrial carrier | 0.213 | INHERITED FROM: Deoxyribonucleosides || Thymidine || Tunicamycin |
| Growth factor receptor domain | 0.2135 | INHERITED FROM: secoisolariciresinol diglucoside || Ribonucleosides || Deoxyglucose |
| Serpins | 0.2192 | INHERITED FROM: periodate-oxidized adenosine |
| Platelet-derived growth factor-like | 0.2196 | INHERITED FROM: delphinidin || cyanidin || Etoposide || Anthocyanins |
| BC ATP-binding domain-like | 0.2196 | INHERITED FROM: Monosaccharides || Hexoses || Sugars |
| BC N-terminal domain-like | 0.2196 | INHERITED FROM: Monosaccharides || Hexoses || Sugars |
| Frizzled cysteine-rich domain | 0.2433 | INHERITED FROM: Arabinonucleosides |
| FAD-linked reductases, N-terminal domain | 0.2438 | INHERITED FROM: periodate-oxidized adenosine |
| Carbonic anhydrase | 0.2451 | INHERITED FROM: Monosaccharides || Hexoses || 4-(4-((glucopyranosyl)thiomethyl)-5-iodo-1-H-1,2,3-triazol-1-yl)benzenesulfonamide || Ketoses || Sugars || Topiramate || 4-(4-((2',3',4',6'-tetra-O-acetylglucopyranosyl)thiomethyl)-5-iodo-1-H-1,2,3-triazol-1-yl)benzenesul || Fructose |
| MHC antigen-recognition domain | 0.2495 | INHERITED FROM: Glycerophospholipids || Lincosamides || Vancomycin || Phosphatidylcholines || Glycopeptides || Dideoxynucleosides || Phosphatidic Acids || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine |
| PurM C-terminal domain-like | 0.2571 | INHERITED FROM: Decitabine |
| PurM N-terminal domain-like | 0.2571 | INHERITED FROM: Decitabine |
| XPF/Rad1/Mus81 nuclease | 0.2571 | INHERITED FROM: MLN7243 |
| Enolase | 0.2571 | INHERITED FROM: Decitabine |
| Fibronectin type III | 0.2585 | INHERITED FROM: Cytidine |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0.2607 | INHERITED FROM: Dietary Carbohydrates |
| Extended AAA-ATPase domain | 0.2864 | INHERITED FROM: MLN7243 |
| Proton glutamate symport protein | 0.295 | INHERITED FROM: Deoxyribonucleosides || Thymidine || Zidovudine || Dideoxynucleosides |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0.295 | INHERITED FROM: Purine Nucleosides |
| Glycerol-3-phosphate transporter | 0.295 | INHERITED FROM: Thymidine || Zidovudine || Dideoxynucleosides |
| Kringle modules | 0.3011 | INHERITED FROM: Glycosaminoglycans |
| Long-chain cytokines | 0.3049 | INHERITED FROM: Polysaccharides, Bacterial || Glucose || Sugar Alcohols || Glycerophospholipids || Monosaccharides || Amino Sugars || Hexoses || Lipopolysaccharides || Thionucleosides || Sugars || Azathioprine || gemcitabine || Polysaccharides || Phosphatidic Acids || Glycoconjugates |
| FAD/NAD-linked reductases, N-terminal and central domains | 0.3049 | INHERITED FROM: Purine Nucleosides |
| Myeloperoxidase-like | 0.3049 | INHERITED FROM: Glycerophospholipids || Sugar Phosphates || Triose Sugar Alcohols || Glycerophosphates || Phosphatidic Acids |
| Integrin A (or I) domain | 0.3233 | INHERITED FROM: ginsenoside M1 || peracetylated N-azidoacetylmannosamine || ginsenoside Rh1 |
| PLC-like (P variant) | 0.3352 | INHERITED FROM: Sugar Alcohols || Dietary Carbohydrates || Sugar Phosphates |
| FHA domain | 0.3557 | INHERITED FROM: Vidarabine || fludarabine |
| Group II chaperonin (CCT, TRIC), apical domain | 0.3762 | INHERITED FROM: Glycerophospholipids || Phosphatidylcholines || Glycerophosphates || Phosphatidic Acids || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine |
| TB module/8-cys domain | 0.3858 | INHERITED FROM: MLN7243 |
| GLA-domain | 0.4371 | INHERITED FROM: Heparin |
| Histone deacetylase, HDAC | 0.4578 | INHERITED FROM: Saponins || Ginsenosides || ginsenoside Rh2 |
| MMP N-terminal domain | 0.467 | INHERITED FROM: Sugar Acids || Glucose || Saponins || Monosaccharides || Amino Sugars || Deoxycytidine || Hexoses || Ascorbic Acid || Ouabain || Lipopolysaccharides || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || fucoidan || Sugars || Cardiac Glycosides || Hexosamines || bufalin || Polysaccharides || Streptozocin || Glycoconjugates || Glucosamine |
| Actin/HSP70 | 0.5435 | INHERITED FROM: bufalin |
| Hemopexin-like domain | 0.5476 | INHERITED FROM: Glucose || Saponins || Amino Sugars || Purine Nucleosides || Ouabain || Lipopolysaccharides || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || fucoidan || Cardiac Glycosides || Hexosamines || bufalin || Polysaccharides || Streptozocin || Glycoconjugates || Glucosamine |
| Matrix metalloproteases, catalytic domain | 0.5476 | INHERITED FROM: Sugar Acids || Glucose || Saponins || Amino Sugars || Purine Nucleosides || Ascorbic Acid || Ouabain || Lipopolysaccharides || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || fucoidan || Cardiac Glycosides || Hexosamines || bufalin || Polysaccharides || Streptozocin || Glycoconjugates || Glucosamine |
| TNF-like | 0.5516 | INHERITED FROM: Amino Sugars || Lipopolysaccharides || Plicamycin || Hexosamines || Polysaccharides || Glycoconjugates |
| Mammalian PLC | 0.5662 | INHERITED FROM: Sugar Alcohols || Sugar Phosphates |
| Cytochrome p450 reductase N-terminal domain-like | 0.588 | INHERITED FROM: Polysaccharides, Bacterial || Glucose || Sugar Alcohols || Monosaccharides || Hexoses || Lipopolysaccharides || Sugars || Polysaccharides || Glycoconjugates |
| Fibroblast growth factors (FGF) | 0.6136 | INHERITED FROM: Heparitin Sulfate || Polysaccharides || Glycosaminoglycans |
| Chaperone J-domain | 0.64 | INHERITED FROM: Sugar Alcohols || Glycerophospholipids || Sugar Phosphates || Phosphatidylcholines || Triose Sugar Alcohols || Glycerophosphates || Phosphatidic Acids || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine |
| Reprolysin-like | 0.6918 | INHERITED FROM: Arbutin || Glucosamine |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0.6926 | INHERITED FROM: Tunicamycin |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0.6926 | INHERITED FROM: Tunicamycin |
| Cytochrome P450 | 0.7186 | INHERITED FROM: Mannitol || Sugar Alcohols || Purine Nucleosides || stevioside || hesperetin || Guanosine || Dietary Carbohydrates || Oligosaccharides || Cyclodextrins || Starch || Celsior || Disaccharides || Sugars || Dextrins || tamarixetin || Hesperidin || Polysaccharides || Deoxyguanosine |
| Meta-cation ATPase, catalytic domain P | 0.7456 | INHERITED FROM: Ouabain || Cardiac Glycosides || Strophanthins || Cardenolides |
| UDPGT-like | 0.7456 | INHERITED FROM: Sugar Acids || Glucuronates || 4-((methylnitrosoamino)-1-(3-pyridyl)but-1-yl)beta-omega-glucosiduronic acid || Uronic Acids |
| Calcium ATPase, transmembrane domain M | 0.7604 | INHERITED FROM: Ouabain || Cardiac Glycosides || Strophanthins || Cardenolides |
| SNF-like | 0.8085 | INHERITED FROM: Thymidine || Dideoxynucleosides |
| LDH N-terminal domain-like | 0.8676 | INHERITED FROM: Glucose || Monosaccharides || Hexoses || Sugars |
| Lactate & malate dehydrogenases, C-terminal domain | 0.8676 | INHERITED FROM: Glucose || Monosaccharides || Hexoses || Sugars |
| Calcium ATPase, transduction domain A | 0.8847 | INHERITED FROM: Ouabain || Strophanthins || Cardenolides |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.927 | INHERITED FROM: Ouabain || Cardiac Glycosides || Strophanthins || Cardenolides |
| HLH, helix-loop-helix DNA-binding domain | 0.957 | INHERITED FROM: Anthocyanins |
| Ngr ectodomain-like | 0.9572 | INHERITED FROM: Phosphatidylinositol Phosphates || phosphatidylinositol 3,4,5-triphosphate |
| Aquaporin-like | 0.9588 | INHERITED FROM: Glycerol |
| C-type lectin domain | 1 | INHERITED FROM: Platelet Activating Factor || Glyceryl Ethers || Polysaccharides |
| Rhodopsin-like | 1 | INHERITED FROM: oleandrin |
| Interferons/interleukin-10 (IL-10) | 1 | INHERITED FROM: Ribavirin |
| V set domains (antibody variable domain-like) | 1 | INHERITED FROM: glucuronoxylomannan |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| RWD domain | 0 | Direct |
| Stathmin | 0 | Direct |
| Connexin43 | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| C5 cytosine-specific DNA methylase, DCM | 0 | Direct |
| PreBEACH PH-like domain | 0 | Direct |
| Release factor | 0 | Direct |
| TRASH domain | 0 | Direct |
| Alkaline phosphatase | 0 | Direct |
| eIF5a N-terminal domain-like | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| 2'-5'-oligoadenylate synthetase 1, OAS1, second domain | 0 | Direct |
| Serine carboxypeptidase-like | 0 | Direct |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
| FF domain | 0 | Direct |
| RNB domain-like | 0 | Direct |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | Direct |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| DNA ligase | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| Methyl-CpG-binding domain, MBD | 0 | Direct |
| DEATH effector domain, DED | 0 | Direct |
| PWI domain | 0 | Direct |
| S-adenosylhomocystein hydrolase | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | Direct |
| Phosphofructokinase | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| DLC | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | Direct |
| P-domain of calnexin/calreticulin | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| E2F dimerization segment | 0 | Direct |
| 2'-5'-oligoadenylate synthetase 1, OAS1, N-terminal domain | 0 | Direct |
| STAT | 0 | Direct |
| TatD Mg-dependent DNase-like | 0 | Direct |
| DEK C-terminal domain | 0 | Direct |
| Pseudouridine synthase RsuA/RluD | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| a tRNA synthase domain | 0 | Direct |
| Interferon regulatory factor 3 (IRF3), transactivation domain | 0 | Direct |
| Tetrahydrofolate dehydrogenase/cyclohydrolase | 0 | Direct |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
| NOL1/NOP2/sun | 0 | Direct |
| Proteasome activator | 0 | Direct |
| Interferon regulatory factor | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, C-terminal domain | 0 | Direct |
| ATP-dependent DNA ligase catalytic domain | 0 | Direct |
| Starch-binding domain | 0 | Direct |
| Transcription factor STAT-4 N-domain | 0 | Direct |
| SPOC domain | 0 | Direct |
| Transferrin | 0 | Direct |
| MIF4G domain-like | 0 | Direct |
| AAT-like | 0 | Direct |
| DNA/RNA non-specific endonuclease | 0 | Direct |
| Troponin I | 0 | Direct |
| Phoshatidylinositol transfer protein, PITP | 0 | Direct |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| BRK domain-like | 0 | Direct |
| Anticodon-binding domain | 0 | Direct |
| Eukaryotic ODC-like | 0 | Direct |
| B56-like | 0 | Direct |
| Cystathionine synthase-like | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| CPH domain | 0 | Direct |
| Protein prenyltransferases | 0 | Direct |
| Retinoblastoma tumor suppressor domains | 0 | Direct |
| MPP-like | 0 | Direct |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | Direct |
| Phosphoribulokinase/pantothenate kinase | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| 5' to 3' exonuclease catalytic domain | 0 | Direct |
| Oligosaccharide phosphorylase | 0 | Direct |
| Alanine racemase-like, N-terminal domain | 0 | Direct |
| Nitric oxide (NO) synthase oxygenase domain | 0 | Direct |
| DNA polymerase beta-like | 0 | Direct |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | Direct |
| Pseudouridine synthase II TruB | 0 | Direct |
| Calnexin/calreticulin | 0 | Direct |
| GHMP Kinase, N-terminal domain | 0 | Direct |
| Ccg1/TafII250-interacting factor B (Cib) | 0 | Direct |
| AlaX-M N-terminal domain-like | 0 | Direct |
| Cytidylyltransferase | 0 | Direct |
| beta-glycanases | 0 | Direct |
| Variant SAM domain | 0 | Direct |
| Hsp90 middle domain | 0 | Direct |
| Phosphoribosyltransferases (PRTases) | 0 | Direct |
| Nucleoplasmin-like core domain | 0 | Direct |
| Neurotrophin | 0 | Direct |
| Nop domain | 0 | Direct |
| Domain G2 of nidogen-1 | 0 | Direct |
| Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
| Ferredoxin domains from multidomain proteins | 0 | Direct |
| Tissue inhibitor of metalloproteinases, TIMP | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| DNA polymerase I | 0 | Direct |
| Ribosomal protein S18 | 0 | Direct |
| A heparin-binding domain | 0 | Direct |
| Variant RING domain | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| SMAD domain | 0 | Direct |
| RNA methyltransferase FtsJ | 0 | Direct |
| HD domain | 0 | Direct |
| STAT DNA-binding domain | 0 | Direct |
| C-terminal domain of PLC-beta | 0 | Direct |
| DNA ligase/mRNA capping enzyme postcatalytic domain | 0 | Direct |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| BAG domain | 0 | Direct |
| RGC domain | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| PAH2 domain | 0 | Direct |
| Splicing factor U2AF subunits | 0 | Direct |
| Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain | 0 | Direct |
| Ecto-ART | 0 | Direct |
| Tandem AAA-ATPase domain | 0.00006098 | Direct |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0.0000788 | Direct |
| Classic zinc finger, C2H2 | 0.0001062 | Direct |
| Histone lysine methyltransferases | 0.0001286 | Direct |
| Bromodomain | 0.0003363 | Direct |
| PWWP domain | 0.0005522 | Direct |
| Nuclear receptor | 0.001197 | Inherited |
| HMG-box | 0.001727 | Inherited |
| Nuclear receptor ligand-binding domain | 0.00201 | Inherited |
| DEATH domain, DD | 0.003178 | Inherited |
| Leucine zipper domain | 0.004763 | Inherited |
| Protein kinases, catalytic subunit | 0.006735 | Inherited |
| Interleukin 8-like chemokines | 0.006774 | Inherited |
| Cold shock DNA-binding domain-like | 0.009319 | Inherited |
| Third domain of FERM | 0.009319 | Inherited |
| PHD domain | 0.01089 | Inherited |
| A DNA-binding domain in eukaryotic transcription factors | 0.01296 | Inherited |
| Cell cycle transcription factor e2f-dp | 0.01441 | Inherited |
| KRAB domain (Kruppel-associated box) | 0.01851 | Inherited |
| ABC transporter transmembrane region | 0.01873 | Inherited |
| Cation efflux protein transmembrane domain-like | 0.0224 | Inherited |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.0224 | Inherited |
| Anticodon-binding domain of Class II aaRS | 0.0224 | Inherited |
| Interleukin-1 (IL-1) | 0.0224 | Inherited |
| Cyclin | 0.02667 | Inherited |
| Double-stranded RNA-binding domain (dsRBD) | 0.02821 | Inherited |
| Integrin domains | 0.0312 | Inherited |
| Complement control module/SCR domain | 0.03265 | Inherited |
| ABC transporter ATPase domain-like | 0.03296 | Inherited |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0.03445 | Inherited |
| HSP40/DnaJ peptide-binding domain | 0.03445 | Inherited |
| SCAN domain | 0.04024 | Inherited |
| Caspase catalytic domain | 0.041 | Inherited |
| Short-chain cytokines | 0.041 | Inherited |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0.05265 | Inherited |
| Tubulin, C-terminal domain | 0.05559 | Inherited |
| Metallothionein | 0.05874 | Inherited |
| Proteasome subunits | 0.06545 | Inherited |
| Caspase recruitment domain, CARD | 0.06545 | Inherited |
| Hypoxia-inducible factor Hif2a, C-terminal domain | 0.07555 | Inherited |
| ARID domain | 0.07555 | Inherited |
| Papain-like | 0.07555 | Inherited |
| L domain | 0.07937 | Inherited |
| Glutathione S-transferase (GST), C-terminal domain | 0.08259 | Inherited |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0.08314 | Inherited |
| Biotinyl/lipoyl-carrier proteins and domains | 0.08314 | Inherited |
| Glutathione peroxidase-like | 0.08705 | Inherited |
| TNF receptor-like | 0.09528 | Inherited |
| SAP domain | 0.1007 | Inherited |
| Toll/Interleukin receptor TIR domain | 0.1007 | Inherited |
| Bcl-2 inhibitors of programmed cell death | 0.1024 | Inherited |
| NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0.1024 | Inherited |
| C1 set domains (antibody constant domain-like) | 0.1082 | Inherited |
| S100 proteins | 0.1149 | Inherited |
| Aldo-keto reductases (NADP) | 0.1149 | Inherited |
| Rel/Dorsal transcription factors, DNA-binding domain | 0.1166 | Inherited |
| NADPH-cytochrome p450 reductase FAD-binding domain-like | 0.1186 | Inherited |
| BC C-terminal domain-like | 0.1186 | Inherited |
| DNA gyrase/MutL, N-terminal domain | 0.1186 | Inherited |
| NADPH-cytochrome p450 reductase-like | 0.1186 | Inherited |
| GABARAP-like | 0.1186 | Inherited |
| Interleukin 17F, IL-17F | 0.1186 | Inherited |
| DNA gyrase/MutL, second domain | 0.1186 | Inherited |
| Laminin-type module | 0.1227 | Inherited |
| Glutathione S-transferase (GST), N-terminal domain | 0.1275 | Inherited |
| BTB/POZ domain | 0.137 | Inherited |
| PDI-like | 0.1374 | Inherited |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.1561 | Inherited |
| EGF-type module | 0.1599 | Inherited |
| C2 set domains | 0.1609 | Inherited |
| Myb/SANT domain | 0.1611 | Inherited |
| SH2 domain | 0.1726 | Inherited |
| Nuclear receptor coactivator interlocking domain | 0.1754 | Inherited |
| Fibronectin type II module | 0.1816 | Inherited |
| Transforming growth factor (TGF)-beta | 0.1855 | Inherited |
| Canonical RBD | 0.191 | Inherited |
| VWC domain | 0.1963 | Inherited |
| Mitochondrial carrier | 0.213 | Inherited |
| Growth factor receptor domain | 0.2135 | Inherited |
| Serpins | 0.2192 | Inherited |
| Platelet-derived growth factor-like | 0.2196 | Inherited |
| BC ATP-binding domain-like | 0.2196 | Inherited |
| BC N-terminal domain-like | 0.2196 | Inherited |
| Frizzled cysteine-rich domain | 0.2433 | Inherited |
| FAD-linked reductases, N-terminal domain | 0.2438 | Inherited |
| Carbonic anhydrase | 0.2451 | Inherited |
| MHC antigen-recognition domain | 0.2495 | Inherited |
| PurM C-terminal domain-like | 0.2571 | Inherited |
| PurM N-terminal domain-like | 0.2571 | Inherited |
| XPF/Rad1/Mus81 nuclease | 0.2571 | Inherited |
| Enolase | 0.2571 | Inherited |
| Fibronectin type III | 0.2585 | Inherited |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0.2607 | Inherited |
| Extended AAA-ATPase domain | 0.2864 | Inherited |
| Proton glutamate symport protein | 0.295 | Inherited |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0.295 | Inherited |
| Glycerol-3-phosphate transporter | 0.295 | Inherited |
| Kringle modules | 0.3011 | Inherited |
| Long-chain cytokines | 0.3049 | Inherited |
| FAD/NAD-linked reductases, N-terminal and central domains | 0.3049 | Inherited |
| Myeloperoxidase-like | 0.3049 | Inherited |
| Integrin A (or I) domain | 0.3233 | Inherited |
| PLC-like (P variant) | 0.3352 | Inherited |
| FHA domain | 0.3557 | Inherited |
| Group II chaperonin (CCT, TRIC), apical domain | 0.3762 | Inherited |
| TB module/8-cys domain | 0.3858 | Inherited |
| GLA-domain | 0.4371 | Inherited |
| Histone deacetylase, HDAC | 0.4578 | Inherited |
| MMP N-terminal domain | 0.467 | Inherited |
| Actin/HSP70 | 0.5435 | Inherited |
| Hemopexin-like domain | 0.5476 | Inherited |
| Matrix metalloproteases, catalytic domain | 0.5476 | Inherited |
| TNF-like | 0.5516 | Inherited |
| Mammalian PLC | 0.5662 | Inherited |
| Cytochrome p450 reductase N-terminal domain-like | 0.588 | Inherited |
| Fibroblast growth factors (FGF) | 0.6136 | Inherited |
| Chaperone J-domain | 0.64 | Inherited |
| Reprolysin-like | 0.6918 | Inherited |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0.6926 | Inherited |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0.6926 | Inherited |
| Cytochrome P450 | 0.7186 | Inherited |
| Meta-cation ATPase, catalytic domain P | 0.7456 | Inherited |
| UDPGT-like | 0.7456 | Inherited |
| Calcium ATPase, transmembrane domain M | 0.7604 | Inherited |
| SNF-like | 0.8085 | Inherited |
| LDH N-terminal domain-like | 0.8676 | Inherited |
| Lactate & malate dehydrogenases, C-terminal domain | 0.8676 | Inherited |
| Calcium ATPase, transduction domain A | 0.8847 | Inherited |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.927 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.957 | Inherited |
| Ngr ectodomain-like | 0.9572 | Inherited |
| Aquaporin-like | 0.9588 | Inherited |
| C-type lectin domain | 1 | Inherited |
| Rhodopsin-like | 1 | Inherited |
| Interferons/interleukin-10 (IL-10) | 1 | Inherited |
| V set domains (antibody variable domain-like) | 1 | Inherited |
LINKTO: Domain2BO Download and Domain2BO Algorithm
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Supra-domain (Single)( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| BAG domain | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| GFP-like | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Stathmin | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | DIRECT |
| 4Fe-4S ferredoxins | 0 | DIRECT |
| Phosphofructokinase | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| ATP-dependent DNA ligase DNA-binding domain | 0 | DIRECT |
| Fe-S cluster assembly (FSCA) domain-like | 0 | DIRECT |
| A heparin-binding domain | 0 | DIRECT |
| Ribosomal protein L16p/L10e | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| PWI domain | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| Nitric oxide (NO) synthase oxygenase domain | 0 | DIRECT |
| Mediator hinge subcomplex-like | 0 | DIRECT |
| DLC | 0 | DIRECT |
| RGC domain-like | 0 | DIRECT |
| Di-copper centre-containing domain | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| Connexin43 | 0 | DIRECT |
| Alanine racemase C-terminal domain-like | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Transcription factor STAT-4 N-domain | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | DIRECT |
| Indolic compounds 2,3-dioxygenase-like | 0 | DIRECT |
| AhpD-like | 0 | DIRECT |
| C-terminal domain of PLC-beta | 0 | DIRECT |
| Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | DIRECT |
| Trimeric LpxA-like enzymes | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| DEK C-terminal domain | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| LuxS/MPP-like metallohydrolase | 0 | DIRECT |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | DIRECT |
| Uracil-DNA glycosylase-like | 0 | DIRECT |
| Proteasome activator | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| STAT | 0 | DIRECT |
| Nucleoplasmin-like core domain | 0 | DIRECT |
| FMT C-terminal domain-like | 0 | DIRECT |
| PAH2 domain | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| P-domain of calnexin/calreticulin | 0 | DIRECT |
| Release factor | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| beta-beta-alpha zinc fingers | 0.000001129 | DIRECT |
| Nucleic acid-binding proteins | 0.00001741 | DIRECT |
| Class II aaRS and biotin synthetases | 0.0001513 | DIRECT |
| Bromodomain | 0.0001679 | DIRECT |
| Protein kinase-like (PK-like) | 0.0005142 | DIRECT |
| HMG-box | 0.0009004 | DIRECT |
| Nuclear receptor ligand-binding domain | 0.001074 | INHERITED FROM: Teniposide || Cardenolides || Oligosaccharides || Hexoses || Saponins || Epirubicin || Digitoxin || pirarubicin || Cardiac Glycosides || iron(II)-ascorbic acid complex || Sugars || Idarubicin || Digitalis Glycosides || Trifluridine || Glucosides |
| Leucine zipper domain | 0.002656 | INHERITED FROM: Monosaccharides || Hexoses || Pyrimidine Nucleosides || Sugar Alcohols || Amino Sugars || Glucose || Sugars || Glycerophosphates || Lipopolysaccharides || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine || Sugar Phosphates || Glucosamine || Nucleosides || Heparin || MLN7243 |
| BRCT domain | 0.00283 | INHERITED FROM: Daunorubicin || Anthracyclines || Etoposide || MLN7243 || fludarabine |
| P-loop containing nucleoside triphosphate hydrolases | 0.00321 | INHERITED FROM: antibiotic G 418 |
| KRAB domain (Kruppel-associated box) | 0.003447 | INHERITED FROM: Glycosides || Nucleosides || MLN7243 |
| Cyclin-like | 0.003492 | INHERITED FROM: Cardenolides || acteoside || Deoxycytidine || Lamivudine || Zidovudine || allose || Thymidine || Deoxyribonucleosides || Zalcitabine || fludarabine |
| Interleukin 8-like chemokines | 0.003987 | INHERITED FROM: Cardenolides || acteoside || polydatin || lipopolysaccharide, Helicobacter pylori || Hesperidin || Deoxycytidine || Puromycin || Glycerophospholipids || Digoxin || Polysaccharides, Bacterial || Lanatosides || Digitoxin || Polysaccharides || Glycopeptides || beta-Glucans || Strophanthins || Glycoconjugates || lipopolysaccharide, E. coli O26-B6 || Chondroitin Sulfates || Zymosan || Proscillaridin || Amino Sugars || Deoxyribonucleosides || Lipopolysaccharides || Bufanolides || peracetylated N-azidoacetylmannosamine || Digitalis Glycosides || gemcitabine || Digitoxigenin |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.006902 | INHERITED FROM: Teniposide || Cardenolides || Oligosaccharides || Saponins || Epirubicin || Aclarubicin || pirarubicin || Cardiac Glycosides || iron(II)-ascorbic acid complex || Sugars || Idarubicin || Digitalis Glycosides || Trifluridine || Glucosides |
| DNA/RNA polymerases | 0.009038 | INHERITED FROM: Deoxyadenosines || N6-(2-hydroxy-3-buten-1-yl)-2'-deoxyadenosine || 2'-deoxyadenosine |
| A DNA-binding domain in eukaryotic transcription factors | 0.009038 | INHERITED FROM: Sugar Acids || S-Adenosylmethionine || Ascorbic Acid |
| Growth factor receptor domain | 0.009366 | INHERITED FROM: secoisolariciresinol diglucoside || rosavin || Ribonucleosides |
| DNA-binding domain | 0.01043 | INHERITED FROM: Azacitidine || Decitabine || pyrimidin-2-one beta-ribofuranoside |
| Cysteine-rich domain | 0.01289 | INHERITED FROM: Dietary Carbohydrates || Ouabain |
| Caspase-like | 0.01377 | INHERITED FROM: Purine Nucleosides || WP 631 || Sugar Acids || 28-O-acetylbetulin-3-ylglucopyranoside || Vidarabine || Phosphatidic Acids || Monosaccharides || Cladribine || Neutral Glycosphingolipids || Ceramides || Anthocyanins || cyanidin 3-O-glucoside || Gentamicins || Hexoses || ginsenoside Rg3 || Polysaccharides, Bacterial || Ascorbic Acid || Saponins || dihydroceramide || Hexosamines || Epirubicin || obacunone glucoside || Digitoxin || Deoxyadenosines || Polysaccharides || Pyrimidine Nucleosides || 5-phenylselenylmethyl-2'-deoxyuridine || Uridine || Glycopeptides || Bleomycin || Glycoconjugates || Sugar Alcohols || pyrimidin-2-one beta-ribofuranoside || Phosphatidylcholines || Glycolipids || Hyaluronic Acid || paederosidic acid || Deoxyribonucleosides || cinobufotalin || Glucose || Cardiac Glycosides || 2-Chloroadenosine || methyl protodioscin || Sugars || Glycosphingolipids || ginsenoside Rk1 || Lipopolysaccharides || Bufanolides || Sugar Phosphates || 5-methylselenylmethyl-2'-deoxyuridine || Meglumine || Trifluridine || Glucosides || Clofarabine || codonoposide || Ribavirin || indioside D || fludarabine || Adenosine |
| SMAD/FHA domain | 0.01589 | INHERITED FROM: Vidarabine || aucubin || Iridoid Glucosides || Glucosides || Iridoid Glycosides || fludarabine |
| Tudor/PWWP/MBT | 0.01657 | INHERITED FROM: MLN7243 |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0.01667 | INHERITED FROM: Polysaccharides, Bacterial || Sugar Alcohols || Lipopolysaccharides |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.01667 | INHERITED FROM: Polysaccharides, Bacterial || Sugar Alcohols || Lipopolysaccharides |
| FYVE/PHD zinc finger | 0.01962 | INHERITED FROM: beta-glycerophosphoric acid || MLN7243 |
| Complement control module/SCR domain | 0.02077 | INHERITED FROM: Glyceryl Ethers || Phospholipid Ethers || Platelet Activating Factor |
| Integrin domains | 0.02189 | INHERITED FROM: ginsenoside Rh1 || Saponins || peracetylated N-azidoacetylmannosamine || ginsenoside M1 |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.02572 | INHERITED FROM: Azacitidine || Pyrimidine Nucleosides || Nucleosides |
| Retrovirus capsid dimerization domain-like | 0.02609 | INHERITED FROM: MLN7243 |
| BEACH domain | 0.02636 | INHERITED FROM: Daunorubicin || Aminoglycosides || Anthracyclines || Doxorubicin |
| HSP40/DnaJ peptide-binding domain | 0.02636 | INHERITED FROM: Phosphatidic Acids || Glycerophospholipids || Sugar Alcohols || Phosphatidylcholines || Triose Sugar Alcohols || Glycerophosphates || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine || Sugar Phosphates |
| Thyroglobulin type-1 domain | 0.02917 | INHERITED FROM: Dietary Carbohydrates |
| TIMP-like | 0.03001 | INHERITED FROM: Chondroitin || lipopolysaccharide, E. coli O26-B6 || Chondroitin Sulfates |
| FAD/NAD(P)-binding domain | 0.03257 | INHERITED FROM: Purine Nucleosides |
| DEATH domain | 0.03799 | INHERITED FROM: Purine Nucleosides || Vidarabine || Monosaccharides || Cladribine || Deoxycytidine || Hexoses || Saponins || Digitoxin || Polysaccharides || 5-phenylselenylmethyl-2'-deoxyuridine || Uridine || Glycoconjugates || lipopolysaccharide, E. coli O26-B6 || Sugar Alcohols || Phosphatidylcholines || Amino Sugars || Aclarubicin || Deoxyribonucleosides || cinobufotalin || Glucose || Cardiac Glycosides || Glycerophosphates || Lipopolysaccharides || Sugar Phosphates || 5-methylselenylmethyl-2'-deoxyuridine || indioside D || fludarabine || Adenosine |
| Tubulin C-terminal domain-like | 0.04082 | INHERITED FROM: Pyrimidine Nucleosides |
| Toll/Interleukin receptor TIR domain | 0.04454 | INHERITED FROM: Polysaccharides || Glycoconjugates || lipopolysaccharide, E. coli O26-B6 || Lipopolysaccharides |
| Metallothionein | 0.04532 | INHERITED FROM: Decitabine || bleomycetin || Pyrimidine Nucleosides || Glycopeptides || Bleomycin || Glycoconjugates |
| DHS-like NAD/FAD-binding domain | 0.04532 | INHERITED FROM: Monosaccharides || Hexoses || Glucose |
| FnI-like domain | 0.04902 | INHERITED FROM: Phosphatidic Acids || Monosaccharides || ascorbate-2-phosphate || Hexoses || Ascorbic Acid || Hexosamines || Sugar Alcohols || Amino Sugars || Glucose || Triose Sugar Alcohols || Glycerophosphates || Sugar Phosphates || peracetylated N-azidoacetylmannosamine |
| ARID-like | 0.0585 | INHERITED FROM: MLN7243 |
| SET domain | 0.06299 | INHERITED FROM: beta-glycerophosphoric acid |
| S15/NS1 RNA-binding domain | 0.06398 | INHERITED FROM: Sugar Acids || Deoxycytidine || Lamivudine || Ascorbic Acid || Zidovudine || Thymidine || Zalcitabine || Tunicamycin || Dideoxynucleosides |
| Ferritin-like | 0.06398 | INHERITED FROM: Tunicamycin |
| Single hybrid motif | 0.0659 | INHERITED FROM: Monosaccharides || Hexoses |
| Cation efflux protein transmembrane domain-like | 0.0659 | INHERITED FROM: Zidovudine || Thymidine || Deoxyribonucleosides || Dideoxynucleosides |
| PH domain-like | 0.07306 | INHERITED FROM: Daunorubicin || Aminoglycosides |
| SAP domain | 0.07681 | INHERITED FROM: MLN7243 |
| RNA-binding domain, RBD | 0.07867 | INHERITED FROM: MLN7243 |
| ABC transporter transmembrane region | 0.07911 | INHERITED FROM: Sugar Acids || Daunorubicin || Ginsenosides || Hesperidin || Anthracyclines || Gentamicins || Saponins || Glucuronates || Epirubicin || Zidovudine || antibiotic G 418 || Uronic Acids || Thymidine || Deoxyribonucleosides || Etoposide || notoginsenoside R1 || hesperetin |
| Bcl-2 inhibitors of programmed cell death | 0.08094 | INHERITED FROM: Purine Nucleosides || Sugar Acids || Vidarabine || Phosphatidic Acids || Arabinonucleosides || Anthocyanins || N-(2-hydroxypropyl)methacrylamide co-polymer-doxorubicin conjugate || Puromycin || Polysaccharides, Bacterial || Deoxy Sugars || Ascorbic Acid || Saponins || Hexosamines || Deoxyadenosines || cordycepin || ziyuglycoside II || Deoxyglucose || Sugar Alcohols || Amino Sugars || chan su || Plicamycin || paederosidic acid || delphinidin || Cardiac Glycosides || Glycerophosphates || Lipopolysaccharides || Bufanolides || Sugar Phosphates || Meglumine || gemcitabine || Glucosides || platycodin D || Etoposide || indioside D || fludarabine || Adenosine |
| GroEL equatorial domain-like | 0.08094 | INHERITED FROM: Phosphatidic Acids || Glycerophospholipids || Sugar Alcohols || Phosphatidylcholines || Triose Sugar Alcohols || Glycerophosphates || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine || Sugar Phosphates |
| NAD(P)-linked oxidoreductase | 0.09024 | INHERITED FROM: Sugar Acids || Thionucleosides || Azathioprine || Glyceraldehyde || Trioses || daunorubicinol |
| Rudiment single hybrid motif | 0.09793 | INHERITED FROM: Monosaccharides || Hexoses || Sugars |
| 2Fe-2S ferredoxin-like | 0.09793 | INHERITED FROM: Polysaccharides, Bacterial |
| Chromo domain-like | 0.1003 | INHERITED FROM: MLN7243 |
| Kringle-like | 0.1005 | INHERITED FROM: Sugar Acids || Ginsenosides || Phosphatidic Acids || Ascorbic Acid || Saponins || Polysaccharides || Strophanthins || Sugar Alcohols || Glucose || Triose Sugar Alcohols || Glycerophosphates || Glycosaminoglycans || Sugar Phosphates || Ouabain |
| Nucleotidylyl transferase | 0.1008 | INHERITED FROM: Lamivudine || Ascorbic Acid || Zalcitabine |
| Class II aaRS ABD-related | 0.1109 | INHERITED FROM: Ascorbic Acid |
| "Winged helix" DNA-binding domain | 0.1149 | INHERITED FROM: MLN7243 |
| SH2 domain | 0.1185 | INHERITED FROM: 6-hydroxy-3-O-methylkaempferol 6-O-glucopyranoside |
| Glutamine synthetase/guanido kinase | 0.1332 | INHERITED FROM: Etoposide |
| Nuclear receptor coactivator interlocking domain | 0.1485 | INHERITED FROM: Polysaccharides || MLN7243 |
| GroEL-intermediate domain like | 0.1495 | INHERITED FROM: Phosphatidic Acids || Glycerophospholipids || Sugar Alcohols || Phosphatidylcholines || Triose Sugar Alcohols || Glycerophosphates || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine || Sugar Phosphates |
| Fibronectin type III | 0.1716 | INHERITED FROM: Cytidine || Ribonucleosides |
| Thioredoxin-like | 0.1716 | INHERITED FROM: Acetylglucosamine || Streptozocin || 6-O-palmitoylascorbic acid || Glucosamine |
| EGF/Laminin | 0.1755 | INHERITED FROM: Cytidine || Glyceryl Ethers || Glycosaminoglycans || peracetylated N-azidoacetylmannosamine || Ribonucleosides || Phospholipid Ethers || Platelet Activating Factor |
| MHC antigen-recognition domain | 0.1976 | INHERITED FROM: Phosphatidic Acids || Vancomycin || Glycerophospholipids || Glycopeptides || Phosphatidylcholines || Glycerophosphates || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine || Dideoxynucleosides || Lincosamides |
| Frizzled cysteine-rich domain | 0.1995 | INHERITED FROM: Arabinonucleosides |
| Carbonic anhydrase | 0.2025 | INHERITED FROM: Monosaccharides || Hexoses || 4-(4-((2',3',4',6'-tetra-O-acetylglucopyranosyl)thiomethyl)-5-iodo-1-H-1,2,3-triazol-1-yl)benzenesul || Ketoses || Sugars || 4-(4-((glucopyranosyl)thiomethyl)-5-iodo-1-H-1,2,3-triazol-1-yl)benzenesulfonamide || Fructose || Topiramate |
| GroEL apical domain-like | 0.2031 | INHERITED FROM: Phosphatidic Acids || Glycerophospholipids || Sugar Alcohols || Phosphatidylcholines || Triose Sugar Alcohols || Glycerophosphates || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine || Sugar Phosphates |
| Translation proteins SH3-like domain | 0.2031 | INHERITED FROM: MLN7243 |
| Mitochondrial carrier | 0.2083 | INHERITED FROM: Thymidine || Deoxyribonucleosides || Tunicamycin || Stavudine |
| Alkaline phosphatase-like | 0.2137 | INHERITED FROM: Triose Sugar Alcohols || Glycerophosphates || Sugar Phosphates |
| PurM C-terminal domain-like | 0.2226 | INHERITED FROM: Azacitidine || Decitabine |
| PurM N-terminal domain-like | 0.2226 | INHERITED FROM: Azacitidine || Decitabine |
| GINS helical bundle-like | 0.2226 | INHERITED FROM: Thionucleosides || Azathioprine |
| GST C-terminal domain-like | 0.2227 | INHERITED FROM: Hexosamines || Glucosamine |
| Serpins | 0.2322 | INHERITED FROM: periodate-oxidized adenosine || Polysaccharides |
| Cytokine | 0.2419 | INHERITED FROM: Polysaccharides || Glycoconjugates || Chondroitin Sulfates || Thioglycosides || Lipopolysaccharides || Glycosaminoglycans |
| Ras GEF | 0.253 | INHERITED FROM: Strophanthins || Ouabain |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0.2546 | INHERITED FROM: Purine Nucleosides |
| Proton glutamate symport protein | 0.2546 | INHERITED FROM: Zidovudine || Thymidine || Deoxyribonucleosides || Dideoxynucleosides |
| Heme-dependent peroxidases | 0.2614 | INHERITED FROM: Phosphatidic Acids || Glycerophospholipids || Sugar Alcohols || Triose Sugar Alcohols || Glycerophosphates || Sugar Phosphates |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0.2712 | INHERITED FROM: Phosphatidic Acids || Glycerophospholipids || Phosphatidylcholines || Triose Sugar Alcohols || Glycerophosphates || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine || Heparin |
| TNF receptor-like | 0.2758 | INHERITED FROM: Vidarabine || Polysaccharides || Glycoconjugates || lipopolysaccharide, E. coli O26-B6 || Amino Sugars || Lipopolysaccharides || gemcitabine || fludarabine |
| vWA-like | 0.3047 | INHERITED FROM: ginsenoside Rh1 || peracetylated N-azidoacetylmannosamine || ginsenoside M1 |
| TSP-1 type 1 repeat | 0.3069 | INHERITED FROM: Cytarabine |
| Cystine-knot cytokines | 0.3126 | INHERITED FROM: Cardenolides || Anthocyanins || cyanidin || Polysaccharides || Strophanthins || Glycoconjugates || Chondroitin Sulfates || Plicamycin || delphinidin || Cardiac Glycosides || Lipopolysaccharides || Digoxigenin |
| TB module/8-cys domain | 0.3367 | INHERITED FROM: MLN7243 |
| PYP-like sensor domain (PAS domain) | 0.3586 | INHERITED FROM: Anthocyanins || Digoxin || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || Digitalis Glycosides || Ouabain |
| Glutathione synthetase ATP-binding domain-like | 0.3586 | INHERITED FROM: Monosaccharides || Hexoses |
| p53-like transcription factors | 0.3763 | INHERITED FROM: WP 744 || Sugar Acids || 6-hydroxy-3-O-methylkaempferol 6-O-glucopyranoside || Neutral Glycosphingolipids || Ceramides || Anthocyanins || Gentamicins || fucoidan || Deoxy Sugars || Ascorbic Acid || Saponins || Hexosamines || Polysaccharides || Glycopeptides || Glycoconjugates || Amino Sugars || Thioglycosides || Glycolipids || Glycosphingolipids || Lipopolysaccharides |
| GLA-domain | 0.3805 | INHERITED FROM: Heparin |
| MFS general substrate transporter | 0.3832 | INHERITED FROM: Dehydroascorbic Acid || Pyrimidine Nucleosides || Thymidine || Deoxyribonucleosides || Ketoses || 7-(deoxyguanosin-N(2)-yl)aristolactam I || Fructose || Dideoxynucleosides || 7-(deoxyadenosin-N(6)-yl)aristolactam I |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.4043 | INHERITED FROM: Hexoses || Glycerol || Polysaccharides, Bacterial || Polysaccharides || N-(4-O-glycerol-3-methoxybenzyl)nonivamide || Glycoconjugates || Sugar Alcohols || Glucose || Sugars || Lipopolysaccharides |
| Riboflavin synthase domain-like | 0.4043 | INHERITED FROM: Hexoses || Glycerol || Polysaccharides, Bacterial || Polysaccharides || N-(4-O-glycerol-3-methoxybenzyl)nonivamide || Glycoconjugates || Sugar Alcohols || Glucose || Sugars || Lipopolysaccharides |
| FAD-linked reductases, C-terminal domain | 0.4043 | INHERITED FROM: periodate-oxidized adenosine |
| PGBD-like | 0.4043 | INHERITED FROM: Sugar Acids || Monosaccharides || bufalin || Deoxycytidine || fucoidan || Hexoses || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || Ascorbic Acid || Saponins || Hexosamines || Polysaccharides || Streptozocin || Glycoconjugates || Amino Sugars || Glucose || Cardiac Glycosides || Sugars || Lipopolysaccharides || Glucosamine || Ouabain |
| RING/U-box | 0.4249 | INHERITED FROM: MLN7243 |
| EF-hand | 0.4394 | INHERITED FROM: 1-Deoxynojirimycin || miglitol || Imino Pyranoses || Imino Sugars |
| Hemopexin-like domain | 0.4789 | INHERITED FROM: Purine Nucleosides || Monosaccharides || bufalin || Deoxycytidine || fucoidan || Hexoses || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || Ascorbic Acid || Saponins || Hexosamines || Polysaccharides || Streptozocin || Glycoconjugates || Amino Sugars || Glucose || Cardiac Glycosides || Lipopolysaccharides || Glucosamine || Ouabain |
| Flavoproteins | 0.4894 | INHERITED FROM: Sugar Acids || Monosaccharides || Anthocyanins || Hexoses || Polysaccharides, Bacterial || Ascorbic Acid || Saponins || Polysaccharides || Glycoconjugates || Sugar Alcohols || Glucose || Sugars || Lipopolysaccharides |
| TNF-like | 0.49 | INHERITED FROM: Hexosamines || Polysaccharides || Glycoconjugates || Amino Sugars || Plicamycin || Lipopolysaccharides |
| Metalloproteases ("zincins"), catalytic domain | 0.4964 | INHERITED FROM: fucoidan || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || Ascorbic Acid || Hexosamines || Streptozocin || Amino Sugars || Glucosamine |
| PreATP-grasp domain | 0.5414 | INHERITED FROM: Monosaccharides || Hexoses || Sugars |
| Chaperone J-domain | 0.5569 | INHERITED FROM: Phosphatidic Acids || Glycerophospholipids || Sugar Alcohols || Phosphatidylcholines || Triose Sugar Alcohols || Glycerophosphates || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine || Sugar Phosphates || Tunicamycin |
| PAP/OAS1 substrate-binding domain | 0.5843 | INHERITED FROM: Zidovudine |
| Arginase/deacetylase | 0.5843 | INHERITED FROM: ginsenoside Rh2 || Ginsenosides || Saponins |
| Cytochrome P450 | 0.5914 | INHERITED FROM: Purine Nucleosides || Starch || Hesperidin || Oligosaccharides || Cyclodextrins || Dietary Carbohydrates || Deoxyguanosine || Mannitol || Polysaccharides || Guanosine || Sugar Alcohols || tamarixetin || stevioside || Celsior || Sugars || Disaccharides || Dextrins || hesperetin |
| GroES-like | 0.6109 | INHERITED FROM: Phosphatidylcholines |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.614 | INHERITED FROM: S-Adenosylmethionine |
| SpoIIaa-like | 0.6315 | INHERITED FROM: Zidovudine || Thymidine || Deoxyribonucleosides || Dideoxynucleosides |
| 4-helical cytokines | 0.6565 | INHERITED FROM: Sugar Acids || Phosphatidic Acids || Hesperidin || Thionucleosides || Acetylmuramyl-Alanyl-Isoglutamine || Azathioprine || Deoxycytidine || Gluconates || Muramic Acids || Hexoses || Polysaccharides, Bacterial || Antimony Sodium Gluconate || Epirubicin || Polysaccharides || lipopolysaccharide, E coli O55-B5 || Glycopeptides || beta-Glucans || Glycoconjugates || Lipid A || Sugar Alcohols || Zymosan || Amino Sugars || Thymidine || Deoxyribonucleosides || Glucose || FEC protocol || Teichoic Acids || Lipopolysaccharides || Sugar Phosphates || Glucosamine || gemcitabine || Ribonucleosides || Ribavirin || hesperetin |
| Actin-like ATPase domain | 0.7297 | INHERITED FROM: bufalin |
| SNF-like | 0.7431 | INHERITED FROM: Thymidine || Deoxyribonucleosides || Dideoxynucleosides |
| Calcium ATPase, transmembrane domain M | 0.7734 | INHERITED FROM: Cardenolides || Strophanthins || Ouabain |
| E set domains | 0.8019 | INHERITED FROM: fucoidan |
| POZ domain | 0.8062 | INHERITED FROM: MLN7243 |
| LDH C-terminal domain-like | 0.8117 | INHERITED FROM: Monosaccharides || Hexoses || Glucose || Sugars |
| Calcium ATPase, transduction domain A | 0.8157 | INHERITED FROM: Cardenolides || Strophanthins || Cardiac Glycosides || Ouabain |
| HLH, helix-loop-helix DNA-binding domain | 0.8802 | INHERITED FROM: Anthocyanins |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0.8805 | INHERITED FROM: Glyceryl Ethers || Phospholipid Ethers |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.8903 | INHERITED FROM: Cardenolides || Strophanthins || Cardiac Glycosides || Ouabain |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.8954 | INHERITED FROM: Sugar Acids || 4-((methylnitrosoamino)-1-(3-pyridyl)but-1-yl)beta-omega-glucosiduronic acid || Glucuronates || Uronic Acids |
| Cysteine proteinases | 0.9049 | INHERITED FROM: Chondroitin || Chondroitin Sulfates |
| Aquaporin-like | 0.9059 | INHERITED FROM: Glycerol |
| C-type lectin-like | 0.9628 | INHERITED FROM: Glyceryl Ethers || Glycerophospholipids || Polysaccharides || Platelet Activating Factor |
| L domain-like | 1 | INHERITED FROM: secoisolariciresinol diglucoside || phosphatidylinositol 3,4,5-triphosphate || Phosphatidylinositol Phosphates |
| Immunoglobulin | 1 | INHERITED FROM: Muramic Acids || glucuronoxylomannan || Lincosamides |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: oleandrin |
| RNI-like | 1 | INHERITED FROM: Acetylmuramyl-Alanyl-Isoglutamine || Muramic Acids |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| BAG domain | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| GFP-like | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Stathmin | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| SIS domain | 0 | Direct |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | Direct |
| 4Fe-4S ferredoxins | 0 | Direct |
| Phosphofructokinase | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| ATP-dependent DNA ligase DNA-binding domain | 0 | Direct |
| Fe-S cluster assembly (FSCA) domain-like | 0 | Direct |
| A heparin-binding domain | 0 | Direct |
| Ribosomal protein L16p/L10e | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| PWI domain | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| Nitric oxide (NO) synthase oxygenase domain | 0 | Direct |
| Mediator hinge subcomplex-like | 0 | Direct |
| DLC | 0 | Direct |
| RGC domain-like | 0 | Direct |
| Di-copper centre-containing domain | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| Connexin43 | 0 | Direct |
| Alanine racemase C-terminal domain-like | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Transcription factor STAT-4 N-domain | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | Direct |
| Indolic compounds 2,3-dioxygenase-like | 0 | Direct |
| AhpD-like | 0 | Direct |
| C-terminal domain of PLC-beta | 0 | Direct |
| Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | Direct |
| Trimeric LpxA-like enzymes | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Nop domain | 0 | Direct |
| Ribosomal protein S18 | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| DEK C-terminal domain | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| LuxS/MPP-like metallohydrolase | 0 | Direct |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | Direct |
| Uracil-DNA glycosylase-like | 0 | Direct |
| Proteasome activator | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| BRK domain-like | 0 | Direct |
| STAT | 0 | Direct |
| Nucleoplasmin-like core domain | 0 | Direct |
| FMT C-terminal domain-like | 0 | Direct |
| PAH2 domain | 0 | Direct |
| FF domain | 0 | Direct |
| P-domain of calnexin/calreticulin | 0 | Direct |
| Release factor | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| beta-beta-alpha zinc fingers | 0.000001129 | Direct |
| Nucleic acid-binding proteins | 0.00001741 | Direct |
| Class II aaRS and biotin synthetases | 0.0001513 | Direct |
| Bromodomain | 0.0001679 | Direct |
| Protein kinase-like (PK-like) | 0.0005142 | Direct |
| HMG-box | 0.0009004 | Direct |
| Nuclear receptor ligand-binding domain | 0.001074 | Inherited |
| Leucine zipper domain | 0.002656 | Inherited |
| BRCT domain | 0.00283 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.00321 | Inherited |
| KRAB domain (Kruppel-associated box) | 0.003447 | Inherited |
| Cyclin-like | 0.003492 | Inherited |
| Interleukin 8-like chemokines | 0.003987 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.006902 | Inherited |
| DNA/RNA polymerases | 0.009038 | Inherited |
| A DNA-binding domain in eukaryotic transcription factors | 0.009038 | Inherited |
| Growth factor receptor domain | 0.009366 | Inherited |
| DNA-binding domain | 0.01043 | Inherited |
| Cysteine-rich domain | 0.01289 | Inherited |
| Caspase-like | 0.01377 | Inherited |
| SMAD/FHA domain | 0.01589 | Inherited |
| Tudor/PWWP/MBT | 0.01657 | Inherited |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0.01667 | Inherited |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.01667 | Inherited |
| FYVE/PHD zinc finger | 0.01962 | Inherited |
| Complement control module/SCR domain | 0.02077 | Inherited |
| Integrin domains | 0.02189 | Inherited |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.02572 | Inherited |
| Retrovirus capsid dimerization domain-like | 0.02609 | Inherited |
| BEACH domain | 0.02636 | Inherited |
| HSP40/DnaJ peptide-binding domain | 0.02636 | Inherited |
| Thyroglobulin type-1 domain | 0.02917 | Inherited |
| TIMP-like | 0.03001 | Inherited |
| FAD/NAD(P)-binding domain | 0.03257 | Inherited |
| DEATH domain | 0.03799 | Inherited |
| Tubulin C-terminal domain-like | 0.04082 | Inherited |
| Toll/Interleukin receptor TIR domain | 0.04454 | Inherited |
| Metallothionein | 0.04532 | Inherited |
| DHS-like NAD/FAD-binding domain | 0.04532 | Inherited |
| FnI-like domain | 0.04902 | Inherited |
| ARID-like | 0.0585 | Inherited |
| SET domain | 0.06299 | Inherited |
| S15/NS1 RNA-binding domain | 0.06398 | Inherited |
| Ferritin-like | 0.06398 | Inherited |
| Single hybrid motif | 0.0659 | Inherited |
| Cation efflux protein transmembrane domain-like | 0.0659 | Inherited |
| PH domain-like | 0.07306 | Inherited |
| SAP domain | 0.07681 | Inherited |
| RNA-binding domain, RBD | 0.07867 | Inherited |
| ABC transporter transmembrane region | 0.07911 | Inherited |
| Bcl-2 inhibitors of programmed cell death | 0.08094 | Inherited |
| GroEL equatorial domain-like | 0.08094 | Inherited |
| NAD(P)-linked oxidoreductase | 0.09024 | Inherited |
| Rudiment single hybrid motif | 0.09793 | Inherited |
| 2Fe-2S ferredoxin-like | 0.09793 | Inherited |
| Chromo domain-like | 0.1003 | Inherited |
| Kringle-like | 0.1005 | Inherited |
| Nucleotidylyl transferase | 0.1008 | Inherited |
| Class II aaRS ABD-related | 0.1109 | Inherited |
| "Winged helix" DNA-binding domain | 0.1149 | Inherited |
| SH2 domain | 0.1185 | Inherited |
| Glutamine synthetase/guanido kinase | 0.1332 | Inherited |
| Nuclear receptor coactivator interlocking domain | 0.1485 | Inherited |
| GroEL-intermediate domain like | 0.1495 | Inherited |
| Fibronectin type III | 0.1716 | Inherited |
| Thioredoxin-like | 0.1716 | Inherited |
| EGF/Laminin | 0.1755 | Inherited |
| MHC antigen-recognition domain | 0.1976 | Inherited |
| Frizzled cysteine-rich domain | 0.1995 | Inherited |
| Carbonic anhydrase | 0.2025 | Inherited |
| GroEL apical domain-like | 0.2031 | Inherited |
| Translation proteins SH3-like domain | 0.2031 | Inherited |
| Mitochondrial carrier | 0.2083 | Inherited |
| Alkaline phosphatase-like | 0.2137 | Inherited |
| PurM C-terminal domain-like | 0.2226 | Inherited |
| PurM N-terminal domain-like | 0.2226 | Inherited |
| GINS helical bundle-like | 0.2226 | Inherited |
| GST C-terminal domain-like | 0.2227 | Inherited |
| Serpins | 0.2322 | Inherited |
| Cytokine | 0.2419 | Inherited |
| Ras GEF | 0.253 | Inherited |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0.2546 | Inherited |
| Proton glutamate symport protein | 0.2546 | Inherited |
| Heme-dependent peroxidases | 0.2614 | Inherited |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0.2712 | Inherited |
| TNF receptor-like | 0.2758 | Inherited |
| vWA-like | 0.3047 | Inherited |
| TSP-1 type 1 repeat | 0.3069 | Inherited |
| Cystine-knot cytokines | 0.3126 | Inherited |
| TB module/8-cys domain | 0.3367 | Inherited |
| PYP-like sensor domain (PAS domain) | 0.3586 | Inherited |
| Glutathione synthetase ATP-binding domain-like | 0.3586 | Inherited |
| p53-like transcription factors | 0.3763 | Inherited |
| GLA-domain | 0.3805 | Inherited |
| MFS general substrate transporter | 0.3832 | Inherited |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.4043 | Inherited |
| Riboflavin synthase domain-like | 0.4043 | Inherited |
| FAD-linked reductases, C-terminal domain | 0.4043 | Inherited |
| PGBD-like | 0.4043 | Inherited |
| RING/U-box | 0.4249 | Inherited |
| EF-hand | 0.4394 | Inherited |
| Hemopexin-like domain | 0.4789 | Inherited |
| Flavoproteins | 0.4894 | Inherited |
| TNF-like | 0.49 | Inherited |
| Metalloproteases ("zincins"), catalytic domain | 0.4964 | Inherited |
| PreATP-grasp domain | 0.5414 | Inherited |
| Chaperone J-domain | 0.5569 | Inherited |
| PAP/OAS1 substrate-binding domain | 0.5843 | Inherited |
| Arginase/deacetylase | 0.5843 | Inherited |
| Cytochrome P450 | 0.5914 | Inherited |
| GroES-like | 0.6109 | Inherited |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.614 | Inherited |
| SpoIIaa-like | 0.6315 | Inherited |
| 4-helical cytokines | 0.6565 | Inherited |
| Actin-like ATPase domain | 0.7297 | Inherited |
| SNF-like | 0.7431 | Inherited |
| Calcium ATPase, transmembrane domain M | 0.7734 | Inherited |
| E set domains | 0.8019 | Inherited |
| POZ domain | 0.8062 | Inherited |
| LDH C-terminal domain-like | 0.8117 | Inherited |
| Calcium ATPase, transduction domain A | 0.8157 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.8802 | Inherited |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0.8805 | Inherited |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.8903 | Inherited |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0.8954 | Inherited |
| Cysteine proteinases | 0.9049 | Inherited |
| Aquaporin-like | 0.9059 | Inherited |
| C-type lectin-like | 0.9628 | Inherited |
| L domain-like | 1 | Inherited |
| Immunoglobulin | 1 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
| RNI-like | 1 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Duplex) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50447,-8
50447 - Translation proteins
-8 - ECOD | 0 | DIRECT |
54826,51604
54826 - Enolase N-terminal domain-like
51604 - Enolase C-terminal domain-like | 0 | DIRECT |
-8,54980
-8 - ECOD
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
117018,56091
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
47986,52129
47986 - DEATH domain
52129 - Caspase-like | 0 | DIRECT |
54768,-9
54768 - dsRNA-binding domain-like
-9 - PDB | 0 | DIRECT |
57903,63748
57903 - FYVE/PHD zinc finger
63748 - Tudor/PWWP/MBT | 0 | DIRECT |
63501,50242
63501 - Frizzled cysteine-rich domain
50242 - TIMP-like | 0 | DIRECT |
57667,140996
57667 - beta-beta-alpha zinc fingers
140996 - Hermes dimerisation domain | 0 | DIRECT |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
69012,55874
69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
47005,52777
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
53328,50486
53328 - Formyltransferase
50486 - FMT C-terminal domain-like | 0 | DIRECT |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | DIRECT |
56491,89811
56491 - A heparin-binding domain
89811 - Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | DIRECT |
48371,49899
48371 - ARM repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
49562,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain | 0 | DIRECT |
57184,57610
57184 - Growth factor receptor domain
57610 - Thyroglobulin type-1 domain | 0 | DIRECT |
56112,50729
56112 - Protein kinase-like (PK-like)
50729 - PH domain-like | 0 | DIRECT |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
57414,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like | 0 | DIRECT |
52540,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain | 0 | DIRECT |
57196,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain | 0 | DIRECT |
49417,55550
49417 - p53-like transcription factors
55550 - SH2 domain | 0 | DIRECT |
49265,56112
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
-7,56112
-7 - CATH
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
47060,55681
47060 - S15/NS1 RNA-binding domain
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
48350,55961
48350 - GTPase activation domain, GAP
55961 - Bet v1-like | 0 | DIRECT |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
46565,57938
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | DIRECT |
90188,53649
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | DIRECT |
46966,51045
46966 - Spectrin repeat
51045 - WW domain | 0 | DIRECT |
57196,49265
57196 - EGF/Laminin
49265 - Fibronectin type III | 0 | DIRECT |
47781,47781
47781 - RuvA domain 2-like
47781 - RuvA domain 2-like | 0 | DIRECT |
100934,100934
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
82109,100909
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | DIRECT |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | DIRECT |
48366,47473
48366 - Ras GEF
47473 - EF-hand | 0 | DIRECT |
47576,48065
47576 - Calponin-homology domain, CH-domain
48065 - DBL homology domain (DH-domain) | 0 | DIRECT |
57196,57424
57196 - EGF/Laminin
57424 - LDL receptor-like module | 0 | DIRECT |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
63825,57196
63825 - YWTD domain
57196 - EGF/Laminin | 0 | DIRECT |
51230,47005
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
50104,50249
50104 - Translation proteins SH3-like domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
63748,82199
63748 - Tudor/PWWP/MBT
82199 - SET domain | 0 | DIRECT |
46689,57667
46689 - Homeodomain-like
57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
51419,50621
51419 - PLP-binding barrel
50621 - Alanine racemase C-terminal domain-like | 0 | DIRECT |
48350,50044
48350 - GTPase activation domain, GAP
50044 - SH3-domain | 0 | DIRECT |
102712,-7
102712 - JAB1/MPN domain
-7 - CATH | 0 | DIRECT |
51045,47473
51045 - WW domain
47473 - EF-hand | 0 | DIRECT |
47676,46942
47676 - Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
46942 - Elongation factor TFIIS domain 2 | 0 | DIRECT |
82199,57903
82199 - SET domain
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
53850,53850
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II | 0 | DIRECT |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | DIRECT |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
53300,49899
53300 - vWA-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
49899,63887
49899 - Concanavalin A-like lectins/glucanases
63887 - P-domain of calnexin/calreticulin | 0 | DIRECT |
49785,53187
49785 - Galactose-binding domain-like
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
57667,90229
57667 - beta-beta-alpha zinc fingers
90229 - CCCH zinc finger | 0 | DIRECT |
50447,55186
50447 - Translation proteins
55186 - ThrRS/AlaRS common domain | 0 | DIRECT |
53784,53784
53784 - Phosphofructokinase
53784 - Phosphofructokinase | 0 | DIRECT |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
54236,57889
54236 - Ubiquitin-like
57889 - Cysteine-rich domain | 0 | DIRECT |
82109,82109
82109 - MIR domain
82109 - MIR domain | 0 | DIRECT |
-7,52540
-7 - CATH
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
54534,47473
54534 - FKBP-like
47473 - EF-hand | 0 | DIRECT |
54511,57184
54511 - GFP-like
57184 - Growth factor receptor domain | 0 | DIRECT |
50156,52540
50156 - PDZ domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48092,47655
48092 - Transcription factor STAT-4 N-domain
47655 - STAT | 0 | DIRECT |
47655,49417
47655 - STAT
49417 - p53-like transcription factors | 0 | DIRECT |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0.000004293 | DIRECT |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0.0002661 | DIRECT |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0.00388 | INHERITED FROM: Teniposide || Cardenolides || ginsenoside Re || Oligosaccharides || Hexoses || Saponins || Epirubicin || Digitoxin || pirarubicin || Cardiac Glycosides || Sugars || Idarubicin || Digitalis Glycosides || Trifluridine || Glucosides |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0.006404 | INHERITED FROM: rosavin || Oligosaccharides || Disaccharides |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0.006474 | INHERITED FROM: Nucleosides |
47454,57959
47454 - A DNA-binding domain in eukaryotic transcription factors
57959 - Leucine zipper domain | 0.01377 | INHERITED FROM: S-Adenosylmethionine || Glucose |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0.01667 | INHERITED FROM: Polysaccharides, Bacterial || Sugar Alcohols || Lipopolysaccharides |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0.02189 | INHERITED FROM: Cardenolides || acteoside || Deoxycytidine || Lamivudine || Zidovudine || allose || Thymidine || Deoxyribonucleosides || Cardiac Glycosides || Zalcitabine || Dideoxynucleosides || Ouabain || fludarabine |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0.02636 | INHERITED FROM: Zidovudine || Thymidine || Deoxyribonucleosides || Dideoxynucleosides |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0.02636 | INHERITED FROM: Purine Nucleosides |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.02636 | INHERITED FROM: Nucleosides |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.0282 | INHERITED FROM: MLN7243 |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.02917 | INHERITED FROM: Tunicamycin |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.02922 | INHERITED FROM: Lipopolysaccharides || Ribonucleosides |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0.03134 | INHERITED FROM: Daunorubicin || Doxorubicin |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0.04082 | INHERITED FROM: Pyrimidine Nucleosides |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0.04127 | INHERITED FROM: Phosphatidic Acids || Glycerophospholipids || Sugar Alcohols || Phosphatidylcholines || Triose Sugar Alcohols || Glycerophosphates || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine || Sugar Phosphates |
55486,82895
55486 - Metalloproteases ("zincins"), catalytic domain
82895 - TSP-1 type 1 repeat | 0.04928 | INHERITED FROM: Hexosamines || Amino Sugars || Glucosamine |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0.05123 | INHERITED FROM: Glyceryl Ethers || Heparin || Phospholipid Ethers || Platelet Activating Factor |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0.06398 | INHERITED FROM: Decitabine |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0.06398 | INHERITED FROM: MLN7243 |
47986,47986
47986 - DEATH domain
47986 - DEATH domain | 0.06398 | INHERITED FROM: Sugar Acids || Monosaccharides || Cytidine || Hexoses || Polysaccharides, Bacterial || Polysaccharides || Glycoconjugates || Sugar Alcohols || Glucose || Triose Sugar Alcohols || Sugars || Glycerophosphates || Lipopolysaccharides || Sugar Phosphates || Ribonucleosides |
57184,52058
57184 - Growth factor receptor domain
52058 - L domain-like | 0.06398 | INHERITED FROM: secoisolariciresinol diglucoside || Monosaccharides || Hexoses || Deoxy Sugars || Saponins || Epirubicin || Deoxyglucose || Deoxyribonucleosides || Glucose || Sugars || Glucosides || platycodin D || Ribonucleosides || Etoposide |
52058,57184
52058 - L domain-like
57184 - Growth factor receptor domain | 0.06398 | INHERITED FROM: secoisolariciresinol diglucoside || Monosaccharides || Hexoses || Deoxy Sugars || Saponins || Epirubicin || Deoxyglucose || Deoxyribonucleosides || Glucose || Sugars || Glucosides || platycodin D || Ribonucleosides || Etoposide |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0.06398 | INHERITED FROM: MLN7243 |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0.0659 | INHERITED FROM: Phosphatidic Acids || Glycerophospholipids || Sugar Alcohols || Phosphatidylcholines || Triose Sugar Alcohols || Glycerophosphates || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine || Sugar Phosphates |
57440,57440
57440 - Kringle-like
57440 - Kringle-like | 0.0659 | INHERITED FROM: Sugar Acids || Cardenolides || Ginsenosides || Phosphatidic Acids || Monosaccharides || Hexoses || Ascorbic Acid || Saponins || Hexosamines || Polysaccharides || Strophanthins || Sugar Alcohols || Amino Sugars || Glucose || Triose Sugar Alcohols || Cardiac Glycosides || Sugars || Glycerophosphates || Lipopolysaccharides || Sugar Phosphates || Heparin || Ouabain |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.07911 | INHERITED FROM: Sugar Acids || Daunorubicin || Ginsenosides || Hesperidin || Anthracyclines || Gentamicins || Saponins || Glucuronates || Epirubicin || Zidovudine || antibiotic G 418 || Uronic Acids || Thymidine || Deoxyribonucleosides || Etoposide || notoginsenoside R1 || hesperetin |
54452,48726
54452 - MHC antigen-recognition domain
48726 - Immunoglobulin | 0.08016 | INHERITED FROM: Vancomycin || Glycerophospholipids || Glycopeptides || Phosphatidylcholines || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine || Dideoxynucleosides || Lincosamides |
47459,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain) | 0.09024 | INHERITED FROM: Anthocyanins || Sugars || Adenosine |
49417,81296
49417 - p53-like transcription factors
81296 - E set domains | 0.09435 | INHERITED FROM: Sugar Acids || fucoidan || Polysaccharides, Bacterial || Ascorbic Acid || Polysaccharides || Glycopeptides || Glycoconjugates || lipopolysaccharide, E. coli O26-B6 || Lipopolysaccharides || gemcitabine |
47095,47095
47095 - HMG-box
47095 - HMG-box | 0.09793 | INHERITED FROM: Sugar Acids || Ascorbic Acid |
55550,55550
55550 - SH2 domain
55550 - SH2 domain | 0.09793 | INHERITED FROM: Sugar Alcohols || Sugar Phosphates |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0.09793 | INHERITED FROM: Monosaccharides || Hexoses || Sugars |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.1164 | INHERITED FROM: rosavin || Lysophosphatidylcholines || lysophosphatidic acid |
57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like | 0.1246 | INHERITED FROM: Sugar Acids || Vidarabine || Polysaccharides || Glycoconjugates || lipopolysaccharide, E. coli O26-B6 || Amino Sugars || Lipopolysaccharides || gemcitabine || fludarabine |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0.1495 | INHERITED FROM: Phosphatidic Acids || Glycerophospholipids || Sugar Alcohols || Phosphatidylcholines || Triose Sugar Alcohols || Glycerophosphates || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine || Sugar Phosphates |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0.1668 | INHERITED FROM: Hexosamines || Cytarabine |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0.1855 | INHERITED FROM: Phosphatidic Acids || Sugar Alcohols || Triose Sugar Alcohols || Glycerophosphates || Sugar Phosphates |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0.2025 | INHERITED FROM: periodate-oxidized adenosine |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0.2219 | INHERITED FROM: Hexosamines || Amino Sugars || Glucosamine |
81995,81811
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0.2226 | INHERITED FROM: Tunicamycin |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0.2226 | INHERITED FROM: Azacitidine || Decitabine |
53300,81995
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24 | 0.2226 | INHERITED FROM: Tunicamycin |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0.2546 | INHERITED FROM: Purine Nucleosides |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0.3367 | INHERITED FROM: Anthocyanins || delphinidin |
57440,50494
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0.3367 | INHERITED FROM: Phosphatidic Acids || Polysaccharides || Sugar Alcohols || Triose Sugar Alcohols || Glycerophosphates || Sugar Phosphates || Heparin || Ribonucleosides |
56436,57535
56436 - C-type lectin-like
57535 - Complement control module/SCR domain | 0.3431 | INHERITED FROM: Polysaccharides |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0.4043 | INHERITED FROM: Sugar Acids || Monosaccharides || bufalin || Deoxycytidine || fucoidan || Hexoses || 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine || Ascorbic Acid || Saponins || Hexosamines || Polysaccharides || Streptozocin || Glycoconjugates || Amino Sugars || Glucose || Cardiac Glycosides || Sugars || Lipopolysaccharides || Glucosamine || Ouabain |
109640,57667
109640 - KRAB domain (Kruppel-associated box)
57667 - beta-beta-alpha zinc fingers | 0.4194 | INHERITED FROM: MLN7243 |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0.4271 | INHERITED FROM: Inositol Phosphates || Sugar Alcohols || Inositol || Sugar Phosphates |
46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like | 0.4541 | INHERITED FROM: MLN7243 |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0.4578 | INHERITED FROM: Sugar Alcohols || Sugar Phosphates |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0.5732 | INHERITED FROM: bufalin |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0.5843 | INHERITED FROM: Monosaccharides || Hexoses || Dietary Carbohydrates || Glucans || Glucose || Sugars |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0.5843 | INHERITED FROM: Zidovudine |
51695,49562
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.5843 | INHERITED FROM: Sugar Alcohols || Sugar Phosphates |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0.6315 | INHERITED FROM: Monosaccharides || Hexoses || Sugars |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0.6509 | INHERITED FROM: Hexosamines || Polysaccharides || Amino Sugars || Glucosamine |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0.8117 | INHERITED FROM: Monosaccharides || Hexoses || Glucose || Sugars |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.8222 | INHERITED FROM: Cardenolides || Strophanthins || Cardiac Glycosides || Ouabain |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0.8903 | INHERITED FROM: Cardenolides || Strophanthins || Cardiac Glycosides || Ouabain |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50447,-8
50447 - Translation proteins
-8 - ECOD | 0 | Direct |
54826,51604
54826 - Enolase N-terminal domain-like
51604 - Enolase C-terminal domain-like | 0 | Direct |
-8,54980
-8 - ECOD
54980 - EF-G C-terminal domain-like | 0 | Direct |
117018,56091
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
47986,52129
47986 - DEATH domain
52129 - Caspase-like | 0 | Direct |
54768,-9
54768 - dsRNA-binding domain-like
-9 - PDB | 0 | Direct |
57903,63748
57903 - FYVE/PHD zinc finger
63748 - Tudor/PWWP/MBT | 0 | Direct |
63501,50242
63501 - Frizzled cysteine-rich domain
50242 - TIMP-like | 0 | Direct |
57667,140996
57667 - beta-beta-alpha zinc fingers
140996 - Hermes dimerisation domain | 0 | Direct |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
69012,55874
69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
47005,52777
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | Direct |
53328,50486
53328 - Formyltransferase
50486 - FMT C-terminal domain-like | 0 | Direct |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | Direct |
56491,89811
56491 - A heparin-binding domain
89811 - Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | Direct |
48371,49899
48371 - ARM repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
49562,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain | 0 | Direct |
57184,57610
57184 - Growth factor receptor domain
57610 - Thyroglobulin type-1 domain | 0 | Direct |
56112,50729
56112 - Protein kinase-like (PK-like)
50729 - PH domain-like | 0 | Direct |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
57414,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like | 0 | Direct |
52540,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain | 0 | Direct |
57196,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain | 0 | Direct |
49417,55550
49417 - p53-like transcription factors
55550 - SH2 domain | 0 | Direct |
49265,56112
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | Direct |
-7,56112
-7 - CATH
56112 - Protein kinase-like (PK-like) | 0 | Direct |
47060,55681
47060 - S15/NS1 RNA-binding domain
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
48350,55961
48350 - GTPase activation domain, GAP
55961 - Bet v1-like | 0 | Direct |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
46565,57938
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | Direct |
90188,53649
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | Direct |
46966,51045
46966 - Spectrin repeat
51045 - WW domain | 0 | Direct |
57196,49265
57196 - EGF/Laminin
49265 - Fibronectin type III | 0 | Direct |
47781,47781
47781 - RuvA domain 2-like
47781 - RuvA domain 2-like | 0 | Direct |
100934,100934
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
82109,100909
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | Direct |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | Direct |
48366,47473
48366 - Ras GEF
47473 - EF-hand | 0 | Direct |
47576,48065
47576 - Calponin-homology domain, CH-domain
48065 - DBL homology domain (DH-domain) | 0 | Direct |
57196,57424
57196 - EGF/Laminin
57424 - LDL receptor-like module | 0 | Direct |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
63825,57196
63825 - YWTD domain
57196 - EGF/Laminin | 0 | Direct |
51230,47005
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
50104,50249
50104 - Translation proteins SH3-like domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
63748,82199
63748 - Tudor/PWWP/MBT
82199 - SET domain | 0 | Direct |
46689,57667
46689 - Homeodomain-like
57667 - beta-beta-alpha zinc fingers | 0 | Direct |
51419,50621
51419 - PLP-binding barrel
50621 - Alanine racemase C-terminal domain-like | 0 | Direct |
48350,50044
48350 - GTPase activation domain, GAP
50044 - SH3-domain | 0 | Direct |
102712,-7
102712 - JAB1/MPN domain
-7 - CATH | 0 | Direct |
51045,47473
51045 - WW domain
47473 - EF-hand | 0 | Direct |
47676,46942
47676 - Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
46942 - Elongation factor TFIIS domain 2 | 0 | Direct |
82199,57903
82199 - SET domain
57903 - FYVE/PHD zinc finger | 0 | Direct |
53850,53850
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II | 0 | Direct |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | Direct |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
53300,49899
53300 - vWA-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
49899,63887
49899 - Concanavalin A-like lectins/glucanases
63887 - P-domain of calnexin/calreticulin | 0 | Direct |
49785,53187
49785 - Galactose-binding domain-like
53187 - Zn-dependent exopeptidases | 0 | Direct |
57667,90229
57667 - beta-beta-alpha zinc fingers
90229 - CCCH zinc finger | 0 | Direct |
50447,55186
50447 - Translation proteins
55186 - ThrRS/AlaRS common domain | 0 | Direct |
53784,53784
53784 - Phosphofructokinase
53784 - Phosphofructokinase | 0 | Direct |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
54236,57889
54236 - Ubiquitin-like
57889 - Cysteine-rich domain | 0 | Direct |
82109,82109
82109 - MIR domain
82109 - MIR domain | 0 | Direct |
-7,52540
-7 - CATH
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
54534,47473
54534 - FKBP-like
47473 - EF-hand | 0 | Direct |
54511,57184
54511 - GFP-like
57184 - Growth factor receptor domain | 0 | Direct |
50156,52540
50156 - PDZ domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48092,47655
48092 - Transcription factor STAT-4 N-domain
47655 - STAT | 0 | Direct |
47655,49417
47655 - STAT
49417 - p53-like transcription factors | 0 | Direct |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | Direct |
57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0.000004293 | Direct |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0.0002661 | Direct |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0.00388 | Inherited |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0.006404 | Inherited |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0.006474 | Inherited |
47454,57959
47454 - A DNA-binding domain in eukaryotic transcription factors
57959 - Leucine zipper domain | 0.01377 | Inherited |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0.01667 | Inherited |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0.02189 | Inherited |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0.02636 | Inherited |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0.02636 | Inherited |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.02636 | Inherited |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.0282 | Inherited |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.02917 | Inherited |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.02922 | Inherited |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0.03134 | Inherited |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0.04082 | Inherited |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0.04127 | Inherited |
55486,82895
55486 - Metalloproteases ("zincins"), catalytic domain
82895 - TSP-1 type 1 repeat | 0.04928 | Inherited |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0.05123 | Inherited |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0.06398 | Inherited |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0.06398 | Inherited |
47986,47986
47986 - DEATH domain
47986 - DEATH domain | 0.06398 | Inherited |
57184,52058
57184 - Growth factor receptor domain
52058 - L domain-like | 0.06398 | Inherited |
52058,57184
52058 - L domain-like
57184 - Growth factor receptor domain | 0.06398 | Inherited |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0.06398 | Inherited |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0.0659 | Inherited |
57440,57440
57440 - Kringle-like
57440 - Kringle-like | 0.0659 | Inherited |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.07911 | Inherited |
54452,48726
54452 - MHC antigen-recognition domain
48726 - Immunoglobulin | 0.08016 | Inherited |
47459,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain) | 0.09024 | Inherited |
49417,81296
49417 - p53-like transcription factors
81296 - E set domains | 0.09435 | Inherited |
47095,47095
47095 - HMG-box
47095 - HMG-box | 0.09793 | Inherited |
55550,55550
55550 - SH2 domain
55550 - SH2 domain | 0.09793 | Inherited |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0.09793 | Inherited |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.1164 | Inherited |
57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like | 0.1246 | Inherited |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0.1495 | Inherited |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0.1668 | Inherited |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0.1855 | Inherited |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0.2025 | Inherited |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0.2219 | Inherited |
81995,81811
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0.2226 | Inherited |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0.2226 | Inherited |
53300,81995
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24 | 0.2226 | Inherited |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0.2546 | Inherited |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0.3367 | Inherited |
57440,50494
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0.3367 | Inherited |
56436,57535
56436 - C-type lectin-like
57535 - Complement control module/SCR domain | 0.3431 | Inherited |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0.4043 | Inherited |
109640,57667
109640 - KRAB domain (Kruppel-associated box)
57667 - beta-beta-alpha zinc fingers | 0.4194 | Inherited |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0.4271 | Inherited |
46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like | 0.4541 | Inherited |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0.4578 | Inherited |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0.5732 | Inherited |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0.5843 | Inherited |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0.5843 | Inherited |
51695,49562
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.5843 | Inherited |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0.6315 | Inherited |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0.6509 | Inherited |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0.8117 | Inherited |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.8222 | Inherited |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0.8903 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Jump to [ Top · Hierarchy ]
Supra-domain (Triple) in N- to C-terminal order( show details)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50729,50729,48350
50729 - PH domain-like
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | DIRECT |
57414,57440,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like
57440 - Kringle-like | 0 | DIRECT |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
48366,47473,57889
48366 - Ras GEF
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | DIRECT |
57903,63748,82199
57903 - FYVE/PHD zinc finger
63748 - Tudor/PWWP/MBT
82199 - SET domain | 0 | DIRECT |
57196,57424,57424
57196 - EGF/Laminin
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | DIRECT |
50729,55550,56112
50729 - PH domain-like
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
57196,63825,57196
57196 - EGF/Laminin
63825 - YWTD domain
57196 - EGF/Laminin | 0 | DIRECT |
63825,57196,63825
63825 - YWTD domain
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
51230,47005,52777
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
57196,57581,57196
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | DIRECT |
48726,49265,56112
48726 - Immunoglobulin
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
90188,90188,53649
90188 - Somatomedin B domain
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | DIRECT |
54768,54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
100895,100895,100895
100895 - Kazal-type serine protease inhibitors
100895 - Kazal-type serine protease inhibitors
100895 - Kazal-type serine protease inhibitors | 0 | DIRECT |
51045,47473,47473
51045 - WW domain
47473 - EF-hand
47473 - EF-hand | 0 | DIRECT |
57184,52058,57184
57184 - Growth factor receptor domain
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
47655,49417,55550
47655 - STAT
49417 - p53-like transcription factors
55550 - SH2 domain | 0 | DIRECT |
82109,82109,100909
82109 - MIR domain
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
57924,57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
50156,52540,51045
50156 - PDZ domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain | 0 | DIRECT |
47576,48065,50729
47576 - Calponin-homology domain, CH-domain
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | DIRECT |
52540,51045,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain
51045 - WW domain | 0 | DIRECT |
46565,57938,49493
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
81698,81698,81698
81698 - FF domain
81698 - FF domain
81698 - FF domain | 0 | DIRECT |
49265,48726,48726
49265 - Fibronectin type III
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
47220,47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
50729,50729,57863
50729 - PH domain-like
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | DIRECT |
49562,57889,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
63748,82199,57903
63748 - Tudor/PWWP/MBT
82199 - SET domain
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
52058,48726,48726
52058 - L domain-like
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
47986,47986,52129
47986 - DEATH domain
47986 - DEATH domain
52129 - Caspase-like | 0 | DIRECT |
46966,46966,51045
46966 - Spectrin repeat
46966 - Spectrin repeat
51045 - WW domain | 0 | DIRECT |
48092,47655,49417
48092 - Transcription factor STAT-4 N-domain
47655 - STAT
49417 - p53-like transcription factors | 0 | DIRECT |
63411,63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | DIRECT |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
63825,57196,57424
63825 - YWTD domain
57196 - EGF/Laminin
57424 - LDL receptor-like module | 0 | DIRECT |
49785,53187,49464
49785 - Galactose-binding domain-like
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | DIRECT |
55550,56112,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
117018,56091,50249
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
57196,57535,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
50447,-8,54980
50447 - Translation proteins
-8 - ECOD
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
46966,51045,47473
46966 - Spectrin repeat
51045 - WW domain
47473 - EF-hand | 0 | DIRECT |
57667,57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0.00009536 | DIRECT |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0.01667 | INHERITED FROM: Polysaccharides, Bacterial || Sugar Alcohols || Lipopolysaccharides |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0.02636 | INHERITED FROM: Zidovudine || Thymidine || Deoxyribonucleosides || Dideoxynucleosides |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.02636 | INHERITED FROM: Zidovudine || Thymidine || Deoxyribonucleosides || Dideoxynucleosides |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.02636 | INHERITED FROM: Nucleosides |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.02636 | INHERITED FROM: Nucleosides |
57196,57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.04065 | INHERITED FROM: Lysophosphatidylcholines || lysophosphatidic acid |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.0585 | INHERITED FROM: Tunicamycin |
48726,49265,49265
48726 - Immunoglobulin
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.0585 | INHERITED FROM: Cytidine || Ribonucleosides |
57440,57440,57440
57440 - Kringle-like
57440 - Kringle-like
57440 - Kringle-like | 0.06398 | INHERITED FROM: Sugar Acids || Phosphatidic Acids || Lysophospholipids || Ascorbic Acid || sphingosine 1-phosphate || Sugar Alcohols || Triose Sugar Alcohols || Glycerophosphates || Glycosaminoglycans || Sugar Phosphates || Heparin |
52058,57184,52058
52058 - L domain-like
57184 - Growth factor receptor domain
52058 - L domain-like | 0.06398 | INHERITED FROM: secoisolariciresinol diglucoside || Monosaccharides || Hexoses || Deoxy Sugars || Saponins || Epirubicin || Deoxyglucose || Deoxyribonucleosides || Glucose || Sugars || Glucosides || platycodin D || Ribonucleosides || Etoposide |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0.0659 | INHERITED FROM: Phosphatidic Acids || Glycerophospholipids || Sugar Alcohols || Phosphatidylcholines || Triose Sugar Alcohols || Glycerophosphates || oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine || Sugar Phosphates |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0.09793 | INHERITED FROM: Monosaccharides || Hexoses || Sugars |
57440,57440,50494
57440 - Kringle-like
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0.09793 | INHERITED FROM: Ribonucleosides |
57586,57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like
57586 - TNF receptor-like | 0.1855 | INHERITED FROM: Purine Nucleosides || lipopolysaccharide, E. coli O26-B6 || Adenosine |
81995,81811,82754
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0.2226 | INHERITED FROM: Tunicamycin |
53300,81995,81811
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0.2226 | INHERITED FROM: Tunicamycin |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0.3367 | INHERITED FROM: Etoposide |
47459,55785,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0.4271 | INHERITED FROM: Anthocyanins || delphinidin |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0.6197 | INHERITED FROM: Hexosamines || Polysaccharides || Glycoconjugates || Amino Sugars || Lipopolysaccharides || Glucosamine |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.8903 | INHERITED FROM: Cardenolides || Strophanthins || Cardiac Glycosides || Ouabain |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50729,50729,48350
50729 - PH domain-like
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | Direct |
57414,57440,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like
57440 - Kringle-like | 0 | Direct |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
48366,47473,57889
48366 - Ras GEF
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | Direct |
57903,63748,82199
57903 - FYVE/PHD zinc finger
63748 - Tudor/PWWP/MBT
82199 - SET domain | 0 | Direct |
57196,57424,57424
57196 - EGF/Laminin
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | Direct |
50729,55550,56112
50729 - PH domain-like
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
57196,63825,57196
57196 - EGF/Laminin
63825 - YWTD domain
57196 - EGF/Laminin | 0 | Direct |
63825,57196,63825
63825 - YWTD domain
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
51230,47005,52777
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | Direct |
57196,57581,57196
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | Direct |
48726,49265,56112
48726 - Immunoglobulin
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | Direct |
90188,90188,53649
90188 - Somatomedin B domain
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | Direct |
54768,54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
100895,100895,100895
100895 - Kazal-type serine protease inhibitors
100895 - Kazal-type serine protease inhibitors
100895 - Kazal-type serine protease inhibitors | 0 | Direct |
51045,47473,47473
51045 - WW domain
47473 - EF-hand
47473 - EF-hand | 0 | Direct |
57184,52058,57184
57184 - Growth factor receptor domain
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | Direct |
47655,49417,55550
47655 - STAT
49417 - p53-like transcription factors
55550 - SH2 domain | 0 | Direct |
82109,82109,100909
82109 - MIR domain
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
57924,57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
50156,52540,51045
50156 - PDZ domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain | 0 | Direct |
47576,48065,50729
47576 - Calponin-homology domain, CH-domain
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | Direct |
52540,51045,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain
51045 - WW domain | 0 | Direct |
46565,57938,49493
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
81698,81698,81698
81698 - FF domain
81698 - FF domain
81698 - FF domain | 0 | Direct |
49265,48726,48726
49265 - Fibronectin type III
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | Direct |
47220,47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | Direct |
50729,50729,57863
50729 - PH domain-like
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | Direct |
49562,57889,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
63748,82199,57903
63748 - Tudor/PWWP/MBT
82199 - SET domain
57903 - FYVE/PHD zinc finger | 0 | Direct |
52058,48726,48726
52058 - L domain-like
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | Direct |
47986,47986,52129
47986 - DEATH domain
47986 - DEATH domain
52129 - Caspase-like | 0 | Direct |
46966,46966,51045
46966 - Spectrin repeat
46966 - Spectrin repeat
51045 - WW domain | 0 | Direct |
48092,47655,49417
48092 - Transcription factor STAT-4 N-domain
47655 - STAT
49417 - p53-like transcription factors | 0 | Direct |
63411,63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | Direct |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
63825,57196,57424
63825 - YWTD domain
57196 - EGF/Laminin
57424 - LDL receptor-like module | 0 | Direct |
49785,53187,49464
49785 - Galactose-binding domain-like
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | Direct |
55550,56112,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
117018,56091,50249
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
57196,57535,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
50447,-8,54980
50447 - Translation proteins
-8 - ECOD
54980 - EF-G C-terminal domain-like | 0 | Direct |
46966,51045,47473
46966 - Spectrin repeat
51045 - WW domain
47473 - EF-hand | 0 | Direct |
57667,57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0.00009536 | Direct |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0.01667 | Inherited |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0.02636 | Inherited |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.02636 | Inherited |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.02636 | Inherited |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.02636 | Inherited |
57196,57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.04065 | Inherited |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.0585 | Inherited |
48726,49265,49265
48726 - Immunoglobulin
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.0585 | Inherited |
57440,57440,57440
57440 - Kringle-like
57440 - Kringle-like
57440 - Kringle-like | 0.06398 | Inherited |
52058,57184,52058
52058 - L domain-like
57184 - Growth factor receptor domain
52058 - L domain-like | 0.06398 | Inherited |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0.0659 | Inherited |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0.09793 | Inherited |
57440,57440,50494
57440 - Kringle-like
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0.09793 | Inherited |
57586,57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like
57586 - TNF receptor-like | 0.1855 | Inherited |
81995,81811,82754
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0.2226 | Inherited |
53300,81995,81811
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0.2226 | Inherited |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0.3367 | Inherited |
47459,55785,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0.4271 | Inherited |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0.6197 | Inherited |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.8903 | Inherited |
LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm
Plot distribution on species Tree Of Life (sTOL) for Superfamily and/or Family domains annotated by this CC term
 |
Plot tree as:
| |
Download Newick format tree:
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( show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domain
architecture data for all genomes in SUPERFAMILY. The PAUP
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
Plot distribution on species Tree Of Life (sTOL) for single supra-domains annotated by this CC term
|
Plot tree as:
| |
Download Newick format tree:
| |
Browsing in TREE OF LIFE:
|
( show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
|
|
> BO Hierarchy > Carbohydrates
